Serping1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Serping1
Entrez Gene ID	12258
Full Name	serine (or cysteine) peptidase inhibitor, clade G, member 1
Synonyms	C1INH,C1nh
General protein information	Preferred Names serine (or cysteine) peptidase inhibitor, clade G, member 1 Names plasma protease C1 inhibitor C1 Inh C1 esterase inhibitor C1 inhibitor C1-inhibiting factor complement component 1 inhibitor serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 serine (or cysteine) proteinase inhibitor, clade G, member 1 serpin G1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 D

mRNA and Protein(s)

mRNA	Protein	Name
NM_009776.3	NP_033906.2	plasma protease C1 inhibitor precursor
XM_006498623.2	XP_006498686.1	plasma protease C1 inhibitor isoform X1
XM_006498623.3	XP_006498686.1	plasma protease C1 inhibitor isoform X1

Pathways from BioSystems

Homologies

	SERPING1	XP_001092271.2
Homo sapiens (human)	SERPING1	NP_000053.2
Canis lupus familiaris (dog)	SERPING1	XP_005631775.1
Bos taurus (cattle)	SERPING1	NP_777246.1
Rattus norvegicus (Norway rat)	Serping1	NP_954524.1
Danio rerio (zebrafish)	serping1	NP_001116757.1
Pan troglodytes (chimpanzee)	SERPING1	XP_003318026.1
Mus musculus (house mouse)	Serping1	NP_033906.2
Gallus gallus (chicken)	SERPING1	XP_003641424.1

Gene Ontology
Bibliography

Related articles in PubMed

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A
Developmental cell41(4)349-365.e3(2017 05)

Update of the human and mouse SERPIN gene superfamily.
Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman GA, Nebert DW, Vasiliou V
Human genomics722(2013 Oct)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S
Proceedings of the National Academy of Sciences of the United States of America110(6)E507-16(2013 Feb)

The effect of C1 inhibitor on myocardial ischemia and reperfusion injury.
Lu F, Fernandes SM, Davis AE 3rd
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology22(1)75-80(2013 Jan-Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

C1INH prevented myocardial ischemia reperfusion injury in mice.
Title: The effect of C1 inhibitor on myocardial ischemia and reperfusion injury.

In addition to the protective activities mediated via inhibition of the complement system, these studies indicate that C1INH also plays a direct role in suppression of leukocyte transmigration into reperfused tissue.
Title: The effect of C1 inhibitor on intestinal ischemia and reperfusion injury.

C1-inhibitor limits neointimal plaque formation and inflammation. This may involve blockade of complement activation, inhibition of leukocyte recruitment, and reduced triglyceride levels
Title: C1-esterase inhibitor protects against neointima formation after arterial injury in atherosclerosis-prone mice.

In vivo, C1 inhibitor (C1INH) reduces the number of viable bacteria in the blood and peritoneal fluid and accelerates killing of bacteria by blood neutrophils and peritoneal macrophages.
Title: C1 inhibitor-mediated protection from sepsis.

Transgenic mice have been generated that express human C1 inhibitor mRNA and protein under the control of the human promoter and regulatory elements; C1nh production is demonstrated in mouse brain, spleen, liver, heart, kidney, and lung.
Title: In vivo biosynthesis of endogenous and of human C1 inhibitor in transgenic mice: tissue distribution and colocalization of their expression.

The following Serping1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Serping1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04814	NM_009776.3 Latest version!	Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
OMu04814	XM_006498623.3 Latest version!	Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
View Old Accession Versions >>
OMu04814	XM_006498623.2	Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Serping1 ( NM_009776.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033906.2 Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), mRNA.

Price & Availability↑

CloneID	OMu04814
Clone ID Related Accession (Same CDS sequence)	NM_009776.3 , XM_006498623.2 , XM_006498623.3
Accession Version	NM_009776.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	plasma protease C1 inhibitor precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA458230.1, Y10386.1, AA237518.1 and BQ031701.1. On Dec 22, 2007 this sequence version replaced NM_009776.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y10386.1, AF010254.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCCA GGCTGACCCC ACTGACCCTC CTGCTGCTGC TGCTGGCTGG GGATAGAGCC 
TTCTCAGATC CCGAAGCTAC CAGCCACAGC ACCCAGGATC CACTGGAGGC TCAAGCGAAA 
AGCAGAGAGA GCTTCCCTGA AAGAGATGAC TCCTGGAGTC CCCCAGAGCC TACAGTACTG 
CCCTCTACCT GGCCAACAAC CAGTGTAGCC ATCACAATAA CAAATGACAC CATGGGTAAA 
GTAGCCAACG AGTCCTTCAG CCAGCACAGC CAGCCAGCTG CTCAGCTACC CACAGATTCT 
CCAGGACAGC CCCCTCTGAA TTCTTCCAGC CAGCCCTCCA CTGCCTCAGA TCTTCCCACC 
CAGGCTACTA CTGAACCCTT CTGCCCGGAG CCGCTTGCTC AGTGCTCTGA TTCAGACAGA 
GACTCCTCAG AGGCAAAGCT CTCAGAGGCT TTGACAGATT TCTCTGTGAA GCTCTACCAC 
GCCTTCTCAG CTACCAAGAT GGCTAAGACC AACATGGCCT TTTCCCCATT CAGCATTGCC 
AGCCTCCTCA CACAGGTTCT TCTTGGGGCT GGAGACAGCA CCAAGAGCAA CTTGGAGAGC 
ATCCTTTCCT ACCCCAAGGA TTTTGCCTGT GTCCACCAAG CACTAAAGGG CTTTTCATCC 
AAAGGTGTCA CTTCTGTGTC TCAGATTTTC CACAGCCCAG ATCTGGCCAT AAGGGACACC 
TATGTGAATG CATCTCAGAG CCTGTATGGA AGCAGCCCCA GAGTCCTGGG CCCAGACAGT 
GCTGCTAACT TAGAACTCAT CAACACCTGG GTGGCTGAGA ACACCAACCA TAAGATCCGC 
AAGCTGCTGG ACAGCCTGCC TTCTGACACC TGCCTCGTCC TTCTCAATGC TGTCTACTTG 
AGTGCCAAGT GGAAGATAAC ATTTGAACCA AAAAAGATGA TGGCGCCTTT CTTCTACAAA 
AACTCTATGA TTAAAGTGCC CATGATGAGT AGCGTAAAGT ACCCTGTGGC CCAATTCGAT 
GACCATACTT TGAAGGCCAA GGTGGGACAG CTGCAGCTCT CTCACAACCT GAGCTTTGTG 
ATCGTGGTAC CCGTGTTCCC AAAGCACCAA CTTAAAGATG TAGAAAAGGC TCTCAACCCC 
ACTGTCTTCA AGGCCATCAT GAAGAAGCTG GAGCTGTCCA AATTCCTGCC CACTTACCTG 
ACGATGCCTC ATATAAAAGT AAAGAGCAGC CAAGACATGC TGTCAGTCAT GGAGAAACTG 
GAATTCTTTG ACTTCACTTA CGATCTCAAC CTGTGCGGGC TGACCGAGGA CCCAGATCTT 
CAGGTGTCTG CCATGAAACA CGAGACAGTG CTGGAACTGA CAGAGTCAGG GGTGGAAGCA 
GCTGCAGCCT CTGCCATCTC CTTTGGCCGA AGCTTACCCA TCTTTGAGGT GCAGCGACCT 
TTCCTCTTCC TGCTCTGGGA CCAGCAACAC AGGTTCCCAG TCTTCATGGG TCGTGTATAT 
GACCCCAGGG GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033906.2
CDS	92..1606
Translation	MASRLTPLTLLLLLLAGDRAFSDPEATSHSTQDPLEAQAKSRESFPERDDSWSPPEPTVLPSTWPTTSVAITITNDTMGKVANESFSQHSQPAAQLPTDSPGQPPLNSSSQPSTASDLPTQATTEPFCPEPLAQCSDSDRDSSEAKLSEALTDFSVKLYHAFSATKMAKTNMAFSPFSIASLLTQVLLGAGDSTKSNLESILSYPKDFACVHQALKGFSSKGVTSVSQIFHSPDLAIRDTYVNASQSLYGSSPRVLGPDSAANLELINTWVAENTNHKIRKLLDSLPSDTCLVLLNAVYLSAKWKITFEPKKMMAPFFYKNSMIKVPMMSSVKYPVAQFDDHTLKAKVGQLQLSHNLSFVIVVPVFPKHQLKDVEKALNPTVFKAIMKKLELSKFLPTYLTMPHIKVKSSQDMLSVMEKLEFFDFTYDLNLCGLTEDPDLQVSAMKHETVLELTESGVEAAAASAISFGRSLPIFEVQRPFLFLLWDQQHRFPVFMGRVYDPRG

Target ORF information:

RefSeq Version	NM_009776.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009776.3

ORF Insert Sequence:

ATGGCCTCCA GGCTGACCCC ACTGACCCTC CTGCTGCTGC TGCTGGCTGG GGATAGAGCC 
TTCTCAGATC CCGAAGCTAC CAGCCACAGC ACCCAGGATC CACTGGAGGC TCAAGCGAAA 
AGCAGAGAGA GCTTCCCTGA AAGAGATGAC TCCTGGAGTC CCCCAGAGCC TACAGTACTG 
CCCTCTACCT GGCCAACAAC CAGTGTAGCC ATCACAATAA CAAATGACAC CATGGGTAAA 
GTAGCCAACG AGTCCTTCAG CCAGCACAGC CAGCCAGCTG CTCAGCTACC CACAGATTCT 
CCAGGACAGC CCCCTCTGAA TTCTTCCAGC CAGCCCTCCA CTGCCTCAGA TCTTCCCACC 
CAGGCTACTA CTGAACCCTT CTGCCCGGAG CCGCTTGCTC AGTGCTCTGA TTCAGACAGA 
GACTCCTCAG AGGCAAAGCT CTCAGAGGCT TTGACAGATT TCTCTGTGAA GCTCTACCAC 
GCCTTCTCAG CTACCAAGAT GGCTAAGACC AACATGGCCT TTTCCCCATT CAGCATTGCC 
AGCCTCCTCA CACAGGTTCT TCTTGGGGCT GGAGACAGCA CCAAGAGCAA CTTGGAGAGC 
ATCCTTTCCT ACCCCAAGGA TTTTGCCTGT GTCCACCAAG CACTAAAGGG CTTTTCATCC 
AAAGGTGTCA CTTCTGTGTC TCAGATTTTC CACAGCCCAG ATCTGGCCAT AAGGGACACC 
TATGTGAATG CATCTCAGAG CCTGTATGGA AGCAGCCCCA GAGTCCTGGG CCCAGACAGT 
GCTGCTAACT TAGAACTCAT CAACACCTGG GTGGCTGAGA ACACCAACCA TAAGATCCGC 
AAGCTGCTGG ACAGCCTGCC TTCTGACACC TGCCTCGTCC TTCTCAATGC TGTCTACTTG 
AGTGCCAAGT GGAAGATAAC ATTTGAACCA AAAAAGATGA TGGCGCCTTT CTTCTACAAA 
AACTCTATGA TTAAAGTGCC CATGATGAGT AGCGTAAAGT ACCCTGTGGC CCAATTCGAT 
GACCATACTT TGAAGGCCAA GGTGGGACAG CTGCAGCTCT CTCACAACCT GAGCTTTGTG 
ATCGTGGTAC CCGTGTTCCC AAAGCACCAA CTTAAAGATG TAGAAAAGGC TCTCAACCCC 
ACTGTCTTCA AGGCCATCAT GAAGAAGCTG GAGCTGTCCA AATTCCTGCC CACTTACCTG 
ACGATGCCTC ATATAAAAGT AAAGAGCAGC CAAGACATGC TGTCAGTCAT GGAGAAACTG 
GAATTCTTTG ACTTCACTTA CGATCTCAAC CTGTGCGGGC TGACCGAGGA CCCAGATCTT 
CAGGTGTCTG CCATGAAACA CGAGACAGTG CTGGAACTGA CAGAGTCAGG GGTGGAAGCA 
GCTGCAGCCT CTGCCATCTC CTTTGGCCGA AGCTTACCCA TCTTTGAGGT GCAGCGACCT 
TTCCTCTTCC TGCTCTGGGA CCAGCAACAC AGGTTCCCAG TCTTCATGGG TCGTGTATAT 
GACCCCAGGG GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Serping1 ( XM_006498623.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498686.1 Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu04814
Clone ID Related Accession (Same CDS sequence)	NM_009776.3 , XM_006498623.2 , XM_006498623.3
Accession Version	XM_006498623.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	plasma protease C1 inhibitor isoform X1
Comment

ATGGCCTCCA GGCTGACCCC ACTGACCCTC CTGCTGCTGC TGCTGGCTGG GGATAGAGCC 
TTCTCAGATC CCGAAGCTAC CAGCCACAGC ACCCAGGATC CACTGGAGGC TCAAGCGAAA 
AGCAGAGAGA GCTTCCCTGA AAGAGATGAC TCCTGGAGTC CCCCAGAGCC TACAGTACTG 
CCCTCTACCT GGCCAACAAC CAGTGTAGCC ATCACAATAA CAAATGACAC CATGGGTAAA 
GTAGCCAACG AGTCCTTCAG CCAGCACAGC CAGCCAGCTG CTCAGCTACC CACAGATTCT 
CCAGGACAGC CCCCTCTGAA TTCTTCCAGC CAGCCCTCCA CTGCCTCAGA TCTTCCCACC 
CAGGCTACTA CTGAACCCTT CTGCCCGGAG CCGCTTGCTC AGTGCTCTGA TTCAGACAGA 
GACTCCTCAG AGGCAAAGCT CTCAGAGGCT TTGACAGATT TCTCTGTGAA GCTCTACCAC 
GCCTTCTCAG CTACCAAGAT GGCTAAGACC AACATGGCCT TTTCCCCATT CAGCATTGCC 
AGCCTCCTCA CACAGGTTCT TCTTGGGGCT GGAGACAGCA CCAAGAGCAA CTTGGAGAGC 
ATCCTTTCCT ACCCCAAGGA TTTTGCCTGT GTCCACCAAG CACTAAAGGG CTTTTCATCC 
AAAGGTGTCA CTTCTGTGTC TCAGATTTTC CACAGCCCAG ATCTGGCCAT AAGGGACACC 
TATGTGAATG CATCTCAGAG CCTGTATGGA AGCAGCCCCA GAGTCCTGGG CCCAGACAGT 
GCTGCTAACT TAGAACTCAT CAACACCTGG GTGGCTGAGA ACACCAACCA TAAGATCCGC 
AAGCTGCTGG ACAGCCTGCC TTCTGACACC TGCCTCGTCC TTCTCAATGC TGTCTACTTG 
AGTGCCAAGT GGAAGATAAC ATTTGAACCA AAAAAGATGA TGGCGCCTTT CTTCTACAAA 
AACTCTATGA TTAAAGTGCC CATGATGAGT AGCGTAAAGT ACCCTGTGGC CCAATTCGAT 
GACCATACTT TGAAGGCCAA GGTGGGACAG CTGCAGCTCT CTCACAACCT GAGCTTTGTG 
ATCGTGGTAC CCGTGTTCCC AAAGCACCAA CTTAAAGATG TAGAAAAGGC TCTCAACCCC 
ACTGTCTTCA AGGCCATCAT GAAGAAGCTG GAGCTGTCCA AATTCCTGCC CACTTACCTG 
ACGATGCCTC ATATAAAAGT AAAGAGCAGC CAAGACATGC TGTCAGTCAT GGAGAAACTG 
GAATTCTTTG ACTTCACTTA CGATCTCAAC CTGTGCGGGC TGACCGAGGA CCCAGATCTT 
CAGGTGTCTG CCATGAAACA CGAGACAGTG CTGGAACTGA CAGAGTCAGG GGTGGAAGCA 
GCTGCAGCCT CTGCCATCTC CTTTGGCCGA AGCTTACCCA TCTTTGAGGT GCAGCGACCT 
TTCCTCTTCC TGCTCTGGGA CCAGCAACAC AGGTTCCCAG TCTTCATGGG TCGTGTATAT 
GACCCCAGGG GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_006498686.1

Translation

MASRLTPLTLLLLLLAGDRAFSDPEATSHSTQDPLEAQAKSRESFPERDDSWSPPEPTVLPSTWPTTSVAITITNDTMGKVANESFSQHSQPAAQLPTDSPGQPPLNSSSQPSTASDLPTQATTEPFCPEPLAQCSDSDRDSSEAKLSEALTDFSVKLYHAFSATKMAKTNMAFSPFSIASLLTQVLLGAGDSTKSNLESILSYPKDFACVHQALKGFSSKGVTSVSQIFHSPDLAIRDTYVNASQSLYGSSPRVLGPDSAANLELINTWVAENTNHKIRKLLDSLPSDTCLVLLNAVYLSAKWKITFEPKKMMAPFFYKNSMIKVPMMSSVKYPVAQFDDHTLKAKVGQLQLSHNLSFVIVVPVFPKHQLKDVEKALNPTVFKAIMKKLELSKFLPTYLTMPHIKVKSSQDMLSVMEKLEFFDFTYDLNLCGLTEDPDLQVSAMKHETVLELTESGVEAAAASAISFGRSLPIFEVQRPFLFLLWDQQHRFPVFMGRVYDPRG

Target ORF information:

RefSeq Version	XM_006498623.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498623.2

ORF Insert Sequence:

ATGGCCTCCA GGCTGACCCC ACTGACCCTC CTGCTGCTGC TGCTGGCTGG GGATAGAGCC 
TTCTCAGATC CCGAAGCTAC CAGCCACAGC ACCCAGGATC CACTGGAGGC TCAAGCGAAA 
AGCAGAGAGA GCTTCCCTGA AAGAGATGAC TCCTGGAGTC CCCCAGAGCC TACAGTACTG 
CCCTCTACCT GGCCAACAAC CAGTGTAGCC ATCACAATAA CAAATGACAC CATGGGTAAA 
GTAGCCAACG AGTCCTTCAG CCAGCACAGC CAGCCAGCTG CTCAGCTACC CACAGATTCT 
CCAGGACAGC CCCCTCTGAA TTCTTCCAGC CAGCCCTCCA CTGCCTCAGA TCTTCCCACC 
CAGGCTACTA CTGAACCCTT CTGCCCGGAG CCGCTTGCTC AGTGCTCTGA TTCAGACAGA 
GACTCCTCAG AGGCAAAGCT CTCAGAGGCT TTGACAGATT TCTCTGTGAA GCTCTACCAC 
GCCTTCTCAG CTACCAAGAT GGCTAAGACC AACATGGCCT TTTCCCCATT CAGCATTGCC 
AGCCTCCTCA CACAGGTTCT TCTTGGGGCT GGAGACAGCA CCAAGAGCAA CTTGGAGAGC 
ATCCTTTCCT ACCCCAAGGA TTTTGCCTGT GTCCACCAAG CACTAAAGGG CTTTTCATCC 
AAAGGTGTCA CTTCTGTGTC TCAGATTTTC CACAGCCCAG ATCTGGCCAT AAGGGACACC 
TATGTGAATG CATCTCAGAG CCTGTATGGA AGCAGCCCCA GAGTCCTGGG CCCAGACAGT 
GCTGCTAACT TAGAACTCAT CAACACCTGG GTGGCTGAGA ACACCAACCA TAAGATCCGC 
AAGCTGCTGG ACAGCCTGCC TTCTGACACC TGCCTCGTCC TTCTCAATGC TGTCTACTTG 
AGTGCCAAGT GGAAGATAAC ATTTGAACCA AAAAAGATGA TGGCGCCTTT CTTCTACAAA 
AACTCTATGA TTAAAGTGCC CATGATGAGT AGCGTAAAGT ACCCTGTGGC CCAATTCGAT 
GACCATACTT TGAAGGCCAA GGTGGGACAG CTGCAGCTCT CTCACAACCT GAGCTTTGTG 
ATCGTGGTAC CCGTGTTCCC AAAGCACCAA CTTAAAGATG TAGAAAAGGC TCTCAACCCC 
ACTGTCTTCA AGGCCATCAT GAAGAAGCTG GAGCTGTCCA AATTCCTGCC CACTTACCTG 
ACGATGCCTC ATATAAAAGT AAAGAGCAGC CAAGACATGC TGTCAGTCAT GGAGAAACTG 
GAATTCTTTG ACTTCACTTA CGATCTCAAC CTGTGCGGGC TGACCGAGGA CCCAGATCTT 
CAGGTGTCTG CCATGAAACA CGAGACAGTG CTGGAACTGA CAGAGTCAGG GGTGGAAGCA 
GCTGCAGCCT CTGCCATCTC CTTTGGCCGA AGCTTACCCA TCTTTGAGGT GCAGCGACCT 
TTCCTCTTCC TGCTCTGGGA CCAGCAACAC AGGTTCCCAG TCTTCATGGG TCGTGTATAT 
GACCCCAGGG GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Serping1 ( XM_006498623.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006498686.1 Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu04814
Clone ID Related Accession (Same CDS sequence)	NM_009776.3 , XM_006498623.2 , XM_006498623.3
Accession Version	XM_006498623.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	plasma protease C1 inhibitor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006498623.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTCCA GGCTGACCCC ACTGACCCTC CTGCTGCTGC TGCTGGCTGG GGATAGAGCC 
TTCTCAGATC CCGAAGCTAC CAGCCACAGC ACCCAGGATC CACTGGAGGC TCAAGCGAAA 
AGCAGAGAGA GCTTCCCTGA AAGAGATGAC TCCTGGAGTC CCCCAGAGCC TACAGTACTG 
CCCTCTACCT GGCCAACAAC CAGTGTAGCC ATCACAATAA CAAATGACAC CATGGGTAAA 
GTAGCCAACG AGTCCTTCAG CCAGCACAGC CAGCCAGCTG CTCAGCTACC CACAGATTCT 
CCAGGACAGC CCCCTCTGAA TTCTTCCAGC CAGCCCTCCA CTGCCTCAGA TCTTCCCACC 
CAGGCTACTA CTGAACCCTT CTGCCCGGAG CCGCTTGCTC AGTGCTCTGA TTCAGACAGA 
GACTCCTCAG AGGCAAAGCT CTCAGAGGCT TTGACAGATT TCTCTGTGAA GCTCTACCAC 
GCCTTCTCAG CTACCAAGAT GGCTAAGACC AACATGGCCT TTTCCCCATT CAGCATTGCC 
AGCCTCCTCA CACAGGTTCT TCTTGGGGCT GGAGACAGCA CCAAGAGCAA CTTGGAGAGC 
ATCCTTTCCT ACCCCAAGGA TTTTGCCTGT GTCCACCAAG CACTAAAGGG CTTTTCATCC 
AAAGGTGTCA CTTCTGTGTC TCAGATTTTC CACAGCCCAG ATCTGGCCAT AAGGGACACC 
TATGTGAATG CATCTCAGAG CCTGTATGGA AGCAGCCCCA GAGTCCTGGG CCCAGACAGT 
GCTGCTAACT TAGAACTCAT CAACACCTGG GTGGCTGAGA ACACCAACCA TAAGATCCGC 
AAGCTGCTGG ACAGCCTGCC TTCTGACACC TGCCTCGTCC TTCTCAATGC TGTCTACTTG 
AGTGCCAAGT GGAAGATAAC ATTTGAACCA AAAAAGATGA TGGCGCCTTT CTTCTACAAA 
AACTCTATGA TTAAAGTGCC CATGATGAGT AGCGTAAAGT ACCCTGTGGC CCAATTCGAT 
GACCATACTT TGAAGGCCAA GGTGGGACAG CTGCAGCTCT CTCACAACCT GAGCTTTGTG 
ATCGTGGTAC CCGTGTTCCC AAAGCACCAA CTTAAAGATG TAGAAAAGGC TCTCAACCCC 
ACTGTCTTCA AGGCCATCAT GAAGAAGCTG GAGCTGTCCA AATTCCTGCC CACTTACCTG 
ACGATGCCTC ATATAAAAGT AAAGAGCAGC CAAGACATGC TGTCAGTCAT GGAGAAACTG 
GAATTCTTTG ACTTCACTTA CGATCTCAAC CTGTGCGGGC TGACCGAGGA CCCAGATCTT 
CAGGTGTCTG CCATGAAACA CGAGACAGTG CTGGAACTGA CAGAGTCAGG GGTGGAAGCA 
GCTGCAGCCT CTGCCATCTC CTTTGGCCGA AGCTTACCCA TCTTTGAGGT GCAGCGACCT 
TTCCTCTTCC TGCTCTGGGA CCAGCAACAC AGGTTCCCAG TCTTCATGGG TCGTGTATAT 
GACCCCAGGG GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006498686.1
CDS	112..1626
Translation	MASRLTPLTLLLLLLAGDRAFSDPEATSHSTQDPLEAQAKSRESFPERDDSWSPPEPTVLPSTWPTTSVAITITNDTMGKVANESFSQHSQPAAQLPTDSPGQPPLNSSSQPSTASDLPTQATTEPFCPEPLAQCSDSDRDSSEAKLSEALTDFSVKLYHAFSATKMAKTNMAFSPFSIASLLTQVLLGAGDSTKSNLESILSYPKDFACVHQALKGFSSKGVTSVSQIFHSPDLAIRDTYVNASQSLYGSSPRVLGPDSAANLELINTWVAENTNHKIRKLLDSLPSDTCLVLLNAVYLSAKWKITFEPKKMMAPFFYKNSMIKVPMMSSVKYPVAQFDDHTLKAKVGQLQLSHNLSFVIVVPVFPKHQLKDVEKALNPTVFKAIMKKLELSKFLPTYLTMPHIKVKSSQDMLSVMEKLEFFDFTYDLNLCGLTEDPDLQVSAMKHETVLELTESGVEAAAASAISFGRSLPIFEVQRPFLFLLWDQQHRFPVFMGRVYDPRG

Target ORF information:

RefSeq Version	XM_006498623.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006498623.3

ORF Insert Sequence:

ATGGCCTCCA GGCTGACCCC ACTGACCCTC CTGCTGCTGC TGCTGGCTGG GGATAGAGCC 
TTCTCAGATC CCGAAGCTAC CAGCCACAGC ACCCAGGATC CACTGGAGGC TCAAGCGAAA 
AGCAGAGAGA GCTTCCCTGA AAGAGATGAC TCCTGGAGTC CCCCAGAGCC TACAGTACTG 
CCCTCTACCT GGCCAACAAC CAGTGTAGCC ATCACAATAA CAAATGACAC CATGGGTAAA 
GTAGCCAACG AGTCCTTCAG CCAGCACAGC CAGCCAGCTG CTCAGCTACC CACAGATTCT 
CCAGGACAGC CCCCTCTGAA TTCTTCCAGC CAGCCCTCCA CTGCCTCAGA TCTTCCCACC 
CAGGCTACTA CTGAACCCTT CTGCCCGGAG CCGCTTGCTC AGTGCTCTGA TTCAGACAGA 
GACTCCTCAG AGGCAAAGCT CTCAGAGGCT TTGACAGATT TCTCTGTGAA GCTCTACCAC 
GCCTTCTCAG CTACCAAGAT GGCTAAGACC AACATGGCCT TTTCCCCATT CAGCATTGCC 
AGCCTCCTCA CACAGGTTCT TCTTGGGGCT GGAGACAGCA CCAAGAGCAA CTTGGAGAGC 
ATCCTTTCCT ACCCCAAGGA TTTTGCCTGT GTCCACCAAG CACTAAAGGG CTTTTCATCC 
AAAGGTGTCA CTTCTGTGTC TCAGATTTTC CACAGCCCAG ATCTGGCCAT AAGGGACACC 
TATGTGAATG CATCTCAGAG CCTGTATGGA AGCAGCCCCA GAGTCCTGGG CCCAGACAGT 
GCTGCTAACT TAGAACTCAT CAACACCTGG GTGGCTGAGA ACACCAACCA TAAGATCCGC 
AAGCTGCTGG ACAGCCTGCC TTCTGACACC TGCCTCGTCC TTCTCAATGC TGTCTACTTG 
AGTGCCAAGT GGAAGATAAC ATTTGAACCA AAAAAGATGA TGGCGCCTTT CTTCTACAAA 
AACTCTATGA TTAAAGTGCC CATGATGAGT AGCGTAAAGT ACCCTGTGGC CCAATTCGAT 
GACCATACTT TGAAGGCCAA GGTGGGACAG CTGCAGCTCT CTCACAACCT GAGCTTTGTG 
ATCGTGGTAC CCGTGTTCCC AAAGCACCAA CTTAAAGATG TAGAAAAGGC TCTCAACCCC 
ACTGTCTTCA AGGCCATCAT GAAGAAGCTG GAGCTGTCCA AATTCCTGCC CACTTACCTG 
ACGATGCCTC ATATAAAAGT AAAGAGCAGC CAAGACATGC TGTCAGTCAT GGAGAAACTG 
GAATTCTTTG ACTTCACTTA CGATCTCAAC CTGTGCGGGC TGACCGAGGA CCCAGATCTT 
CAGGTGTCTG CCATGAAACA CGAGACAGTG CTGGAACTGA CAGAGTCAGG GGTGGAAGCA 
GCTGCAGCCT CTGCCATCTC CTTTGGCCGA AGCTTACCCA TCTTTGAGGT GCAGCGACCT 
TTCCTCTTCC TGCTCTGGGA CCAGCAACAC AGGTTCCCAG TCTTCATGGG TCGTGTATAT 
GACCCCAGGG GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Developmental cell41(4)349-365.e3(2017 05)
Naiman N,Fujioka K,Fujino M,Valerius MT,Potter SS,McMahon AP,Kobayashi A

Update of the human and mouse SERPIN gene superfamily.
Human genomics722(2013 Oct)
Heit C,Jackson BC,McAndrews M,Wright MW,Thompson DC,Silverman GA,Nebert DW,Vasiliou V

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Proceedings of the National Academy of Sciences of the United States of America110(6)E507-16(2013 Feb)
Lumayag S,Haldin CE,Corbett NJ,Wahlin KJ,Cowan C,Turturro S,Larsen PE,Kovacs B,Witmer PD,Valle D,Zack DJ,Nicholson DA,Xu S

The effect of C1 inhibitor on myocardial ischemia and reperfusion injury.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology22(1)75-80(2013 Jan-Feb)
Lu F,Fernandes SM,Davis AE 3rd

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Serping1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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