Bmpr2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bmpr2
Entrez Gene ID	12168
Full Name	bone morphogenetic protein receptor, type II (serine/threonine kinase)
Synonyms	2610024H22Rik,AL117858,AW546137,BB189135,BMP-2,BMPR-2,BMPR-II,BMPRII,BRK-3,Gm20272
General protein information	Preferred Names bone morphogenetic protein receptor, type II (serine/threonine kinase) Names bone morphogenetic protein receptor type-2 BMP type II receptor BMP type-2 receptor bone morphogenic protein receptor, type II (serine/threonine kinase)
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 C2
Summary	This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. [provided by RefSeq, Mar 2013].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006495633.2	XP_006495696.1	bone morphogenetic protein receptor type-2 isoform X1
NM_007561.4	NP_031587.1	bone morphogenetic protein receptor type-2 precursor
XM_006495633.1	XP_006495696.1	bone morphogenetic protein receptor type-2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	BMPR2	NP_001195.2
	BMPR2	XP_001101663.1
Danio rerio (zebrafish)	bmpr2b	NP_001034896.1
Pan troglodytes (chimpanzee)	BMPR2	XP_001172748.1
Mus musculus (house mouse)	Bmpr2	NP_031587.1
Bos taurus (cattle)	BMPR2	XP_002685538.2
Gallus gallus (chicken)	BMPR2	NP_001001465.1
Canis lupus familiaris (dog)	BMPR2	XP_536035.3
Rattus norvegicus (Norway rat)	Bmpr2	NP_536332.1
Xenopus tropicalis (tropical clawed frog)	bmpr2	XP_002937761.2

Gene Ontology
Bibliography

Related articles in PubMed

Bone morphogenetic protein receptors and signal transduction.
Miyazono K, Kamiya Y, Morikawa M
Journal of biochemistry147(1)35-51(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Dual luciferase report assay verified that miR-3065-5p could bind to the 3'UTR of bone morphogenetic protein receptor type II (BMPR2), which dramatically increased in the beginning of odontoblastic differentiation but decreased in the terminal differentiation stage.
Title: miR-3065-5p regulates mouse odontoblastic differentiation partially through bone morphogenetic protein receptor type II.

Disrupting BMPR2 impairs TGFbeta1- and BMP4-mediated elastic fiber assembly and is of pathophysiologic significance in pulmonary arterial hypertension.
Title: Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-? in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension.

Cav-1 depletion, oxidative stress-mediated reduction in BMPRII expression, and enhanced TGF-beta-driven SMAD-2/3 signaling promote pulmonary vascular remodeling in inflamed lungs.
Title: Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-?-driven pulmonary vascular remodeling.

These results suggested that endogenous PTH enhanced BMPR2 expression by a cAMP/PKA/CREB pathway in osteoblasts, and increased RUNX2 expression through transduction of the BMP/pSMAD1/5/8 signaling pathway
Title: Endogenous Parathyroid Hormone Promotes Fracture Healing by Increasing Expression of BMPR2 through cAMP/PKA/CREB Pathway in Mice.

increased BMPR2 signal transduction is linked to fragile X syndrome (FXS) and that the BMPR2-LIMK1 pathway is a putative therapeutic target in patients with FXS and possibly other forms of autism
Title: Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome.

The following Bmpr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bmpr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu27218	XM_006495633.2 Latest version!	Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OMu20171	NM_007561.4 Latest version!	Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OMu27218	XM_006495633.1	Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bmpr2 ( XM_006495633.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495696.1 Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu27218
Clone ID Related Accession (Same CDS sequence)	XM_006495633.2 , XM_006495633.1
Accession Version	XM_006495633.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	bone morphogenetic protein receptor type-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006495633.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTTCCT CGCTGCATCG GCCCTTTCGG GTGCCCTGGC TGCTATGGGC CGTCCTGCTG 
GTCAGCACTA CGGCTGCTTC TCAGAATCAA GAACGGCTGT GTGCATTTAA AGATCCATAT 
CAACAAGATC TTGGGATAGG TGAGAGTCGA ATCTCTCATG AAAATGGGAC AATATTATGT 
TCCAAAGGGA GCACGTGTTA TGGTCTGTGG GAGAAATCAA AAGGGGACAT CAATCTTGTG 
AAACAAGGAT GTTGGTCTCA CATCGGTGAT CCCCAAGAGT GCCACTATGA AGAGTGTGTA 
GTAACTACCA CCCCACCCTC AATTCAGAAT GGAACGTACC GCTTTTGCTG CTGTAGTACA 
GATTTATGTA ATGTCAACTT TACTGAGAAC TTTCCACCCC CTGACACAAC ACCACTCAGT 
CCACCTCATT CATTTAATCG AGATGAAACG ATAATCATTG CTTTGGCATC AGTTTCTGTG 
TTAGCTGTTT TGATAGTCGC CTTATGTTTT GGATACAGAA TGTTGACAGG AGACCGGAAA 
CAGGGTCTTC ACAGCATGAA CATGATGGAG GCGGCAGCAG CAGAGCCCTC CCTTGACCTG 
GATAACCTGA AGCTGCTGGA GCTGATTGGA CGGGGTCGAT ACGGAGCAGT ATATAAAGGT 
TCCTTGGATG AGCGTCCAGT TGCTGTAAAA GTATTTTCTT TTGCAAACCG TCAGAATTTT 
ATAAATGAAA AAAACATTTA CAGAGTGCCT TTGATGGAAC ATGACAACAT TGCTCGCTTC 
ATAGTTGGAG ACGAGAGGCT CACTGCAGAC GGCCGCATGG AGTATTTGCT TGTGATGGAG 
TATTATCCCA ATGGATCTCT GTGCAAATAT CTGAGTCTCC ACACAAGTGA TTGGGTAAGC 
TCTTGCCGTC TGGCTCATTC TGTGACTAGA GGACTGGCTT ATCTTCACAC AGAATTACCA 
CGAGGAGATC ATTATAAACC CGCAATCTCC CACCGAGATT TAAACAGCAG GAATGTCCTG 
GTAAAGAATG ACGGCGCGTG TGTTATCAGT GACTTTGGTT TATCCATGAG GCTAACTGGA 
AATCGGCTGG TGCGCCCAGG GGAAGAAGAT AATGCGGCTA TAAGTGAGGT TGGCACAATT 
CGCTATATGG CACCAGAAGT GCTAGAAGGA GCTGTGAACC TGAGGGACTG TGAGTCAGCT 
CTGAAGCAAG TGGACATGTA TGCGCTTGGA CTCATCTACT GGGAGGTGTT TATGAGGTGT 
ACAGACCTCT TCCCAGGTGA ATCTGTACCA GATTACCAGA TGGCTTTTCA GACAGAAGTT 
GGAAACCATC CCACATTTGA GGATATGCAG GTTCTTGTGT CCAGAGAGAA GCAGAGACCC 
AAGTTCCCAG AAGCCTGGAA AGAAAATAGC CTGGCAGTGA GGTCACTCAA GGAAACAATT 
GAAGACTGCT GGGACCAGGA TGCAGAGGCT CGGCTCACTG CACAGTGTGC TGAGGAGAGG 
ATGGCTGAAC TCATGATGAT ATGGGAGAGA AACAAGTCTG TGAGCCCAAC GGTCAACCCA 
ATGTCAACTG CTATGCAGAA TGAACGCAAC CTGTCACATA ATAGGCGTGT GCCAAAAATC 
GGGCCTTACC CAGATTATTC CTCTTCCTCA TATATTGAAG ACTCTATCCA TCATACTGAC 
AGCATTGTGA AGAATATTTC CTCTGAGCAT TCGATGTCCA GCACACCATT GACAATAGGA 
GAAAAGAATC GAAATTCAAT TAATTATGAA CGACAGCAAG CACAAGCTCG AATCCCTAGC 
CCAGAAACAA GCGTCACAAG CCTGTCCACA AACACAACCA CCACAAACAC CACCGGCCTC 
ACTCCAAGTA CTGGCATGAC CACTATATCT GAGATGCCAT ACCCAGATGA GACACATTTG 
CACGCCACAA ATGTTGCACA GTCAATCGGG CCAACCCCTG TCTGCTTACA GCTGACAGAA 
GAAGACTTGG AGACTAATAA GCTAGATCCA AAAGAAGTTG ATAAGAACCT CAAGGAAAGC 
TCTGATGAGA ATCTCATGGA GCATTCTCTG AAGCAGTTCA GTGGGCCAGA CCCATTGAGC 
AGTACCAGTT CTAGCTTGCT TTATCCACTC ATAAAGCTCG CAGTGGAAGT GACTGGACAA 
CAGGACTTCA CACAGGCTGC AAATGGGCAA GCATGTTTAA TTCCTGATGT TCCACCTGCT 
CAGATCTATC CTCTCCCTAA GCAACAGAAC CTTCCTAAGA GACCTACTAG TTTGCCTTTG 
AACACCAAAA ATTCAACAAA AGAACCCCGG CTAAAATTTG GCAACAAGCA CAAATCAAAC 
TTGAAACAAG TAGAAACTGG AGTTGCCAAG ATGAATACAA TCAATGCAGC AGAGCCTCAT 
GTGGTGACAG TAACTATGAA TGGTGTGGCA GGTAGAAGCC ACAATGTTAA TTCCCATGCT 
GCCACAACCC AGTATGCCAA TGGCGCAGTG CCAGCTGGCC AGGCAGCCAA CATAGTGGCA 
CATAGGTCCC AAGAAATGCT GCAGAATCAA TTTATTGGTG AGGATACCAG GCTGAATATC 
AATTCCAGTC CTGATGAGCA TGAACCTTTA CTGAGACGAG AGCAACAGGC TGGCCATGAT 
GAAGGGGTTC TGGATCGTTT GGTAGATAGG AGGGAACGGC CATTAGAAGG TGGCCGAACA 
AATTCCAATA ACAACAACAG CAATCCATGT TCAGAACAAG ATATCCTTAC ACAAGGTGTT 
ACAAGCACAG CTGCAGATCC TGGGCCATCA AAGCCCAGAA GAGCACAGAG GCCCAATTCT 
CTGGATCTTT CAGCCACAAA TATCCTGGAT GGCAGCAGTA TACAGAGTGA GTCAACACAA 
GATGGCAAAT CAGGATCAGG TGAAAAGATC AAGAGACGTG TGAAAACTCC ATACTCTCTT 
AAGCGGTGGC GCCCGTCCAC CTGGGTCATC TCCACCGAGC CGCTGGACTG TGAGGTCAAC 
AACAATGGCA GTGACAGGGC AGTCCATTCT AAATCTAGCA CTGCTGTGTA CCTTGCAGAG 
GGAGGCACTG CCACGACCAC AGTGTCTAAA GATATAGGAA TGAATTGTCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495696.1
CDS	343..3456
Translation	MTSSLHRPFRVPWLLWAVLLVSTTAASQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDETIIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAAAEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERLTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGACVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEVFMRCTDLFPGESVPDYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSIVKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDETHLHATNVAQSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLSSTSSSLLYPLIKLAVEVTGQQDFTQAANGQACLIPDVPPAQIYPLPKQQNLPKRPTSLPLNTKNSTKEPRLKFGNKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRSHNVNSHAATTQYANGAVPAGQAANIVAHRSQEMLQNQFIGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRTNSNNNNSNPCSEQDILTQGVTSTAADPGPSKPRRAQRPNSLDLSATNILDGSSIQSESTQDGKSGSGEKIKRRVKTPYSLKRWRPSTWVISTEPLDCEVNNNGSDRAVHSKSSTAVYLAEGGTATTTVSKDIGMNCL

Target ORF information:

RefSeq Version	XM_006495633.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495633.2

ORF Insert Sequence:

ATGACTTCCT CGCTGCATCG GCCCTTTCGG GTGCCCTGGC TGCTATGGGC CGTCCTGCTG 
GTCAGCACTA CGGCTGCTTC TCAGAATCAA GAACGGCTGT GTGCATTTAA AGATCCATAT 
CAACAAGATC TTGGGATAGG TGAGAGTCGA ATCTCTCATG AAAATGGGAC AATATTATGT 
TCCAAAGGGA GCACGTGTTA TGGTCTGTGG GAGAAATCAA AAGGGGACAT CAATCTTGTG 
AAACAAGGAT GTTGGTCTCA CATCGGTGAT CCCCAAGAGT GCCACTATGA AGAGTGTGTA 
GTAACTACCA CCCCACCCTC AATTCAGAAT GGAACGTACC GCTTTTGCTG CTGTAGTACA 
GATTTATGTA ATGTCAACTT TACTGAGAAC TTTCCACCCC CTGACACAAC ACCACTCAGT 
CCACCTCATT CATTTAATCG AGATGAAACG ATAATCATTG CTTTGGCATC AGTTTCTGTG 
TTAGCTGTTT TGATAGTCGC CTTATGTTTT GGATACAGAA TGTTGACAGG AGACCGGAAA 
CAGGGTCTTC ACAGCATGAA CATGATGGAG GCGGCAGCAG CAGAGCCCTC CCTTGACCTG 
GATAACCTGA AGCTGCTGGA GCTGATTGGA CGGGGTCGAT ACGGAGCAGT ATATAAAGGT 
TCCTTGGATG AGCGTCCAGT TGCTGTAAAA GTATTTTCTT TTGCAAACCG TCAGAATTTT 
ATAAATGAAA AAAACATTTA CAGAGTGCCT TTGATGGAAC ATGACAACAT TGCTCGCTTC 
ATAGTTGGAG ACGAGAGGCT CACTGCAGAC GGCCGCATGG AGTATTTGCT TGTGATGGAG 
TATTATCCCA ATGGATCTCT GTGCAAATAT CTGAGTCTCC ACACAAGTGA TTGGGTAAGC 
TCTTGCCGTC TGGCTCATTC TGTGACTAGA GGACTGGCTT ATCTTCACAC AGAATTACCA 
CGAGGAGATC ATTATAAACC CGCAATCTCC CACCGAGATT TAAACAGCAG GAATGTCCTG 
GTAAAGAATG ACGGCGCGTG TGTTATCAGT GACTTTGGTT TATCCATGAG GCTAACTGGA 
AATCGGCTGG TGCGCCCAGG GGAAGAAGAT AATGCGGCTA TAAGTGAGGT TGGCACAATT 
CGCTATATGG CACCAGAAGT GCTAGAAGGA GCTGTGAACC TGAGGGACTG TGAGTCAGCT 
CTGAAGCAAG TGGACATGTA TGCGCTTGGA CTCATCTACT GGGAGGTGTT TATGAGGTGT 
ACAGACCTCT TCCCAGGTGA ATCTGTACCA GATTACCAGA TGGCTTTTCA GACAGAAGTT 
GGAAACCATC CCACATTTGA GGATATGCAG GTTCTTGTGT CCAGAGAGAA GCAGAGACCC 
AAGTTCCCAG AAGCCTGGAA AGAAAATAGC CTGGCAGTGA GGTCACTCAA GGAAACAATT 
GAAGACTGCT GGGACCAGGA TGCAGAGGCT CGGCTCACTG CACAGTGTGC TGAGGAGAGG 
ATGGCTGAAC TCATGATGAT ATGGGAGAGA AACAAGTCTG TGAGCCCAAC GGTCAACCCA 
ATGTCAACTG CTATGCAGAA TGAACGCAAC CTGTCACATA ATAGGCGTGT GCCAAAAATC 
GGGCCTTACC CAGATTATTC CTCTTCCTCA TATATTGAAG ACTCTATCCA TCATACTGAC 
AGCATTGTGA AGAATATTTC CTCTGAGCAT TCGATGTCCA GCACACCATT GACAATAGGA 
GAAAAGAATC GAAATTCAAT TAATTATGAA CGACAGCAAG CACAAGCTCG AATCCCTAGC 
CCAGAAACAA GCGTCACAAG CCTGTCCACA AACACAACCA CCACAAACAC CACCGGCCTC 
ACTCCAAGTA CTGGCATGAC CACTATATCT GAGATGCCAT ACCCAGATGA GACACATTTG 
CACGCCACAA ATGTTGCACA GTCAATCGGG CCAACCCCTG TCTGCTTACA GCTGACAGAA 
GAAGACTTGG AGACTAATAA GCTAGATCCA AAAGAAGTTG ATAAGAACCT CAAGGAAAGC 
TCTGATGAGA ATCTCATGGA GCATTCTCTG AAGCAGTTCA GTGGGCCAGA CCCATTGAGC 
AGTACCAGTT CTAGCTTGCT TTATCCACTC ATAAAGCTCG CAGTGGAAGT GACTGGACAA 
CAGGACTTCA CACAGGCTGC AAATGGGCAA GCATGTTTAA TTCCTGATGT TCCACCTGCT 
CAGATCTATC CTCTCCCTAA GCAACAGAAC CTTCCTAAGA GACCTACTAG TTTGCCTTTG 
AACACCAAAA ATTCAACAAA AGAACCCCGG CTAAAATTTG GCAACAAGCA CAAATCAAAC 
TTGAAACAAG TAGAAACTGG AGTTGCCAAG ATGAATACAA TCAATGCAGC AGAGCCTCAT 
GTGGTGACAG TAACTATGAA TGGTGTGGCA GGTAGAAGCC ACAATGTTAA TTCCCATGCT 
GCCACAACCC AGTATGCCAA TGGCGCAGTG CCAGCTGGCC AGGCAGCCAA CATAGTGGCA 
CATAGGTCCC AAGAAATGCT GCAGAATCAA TTTATTGGTG AGGATACCAG GCTGAATATC 
AATTCCAGTC CTGATGAGCA TGAACCTTTA CTGAGACGAG AGCAACAGGC TGGCCATGAT 
GAAGGGGTTC TGGATCGTTT GGTAGATAGG AGGGAACGGC CATTAGAAGG TGGCCGAACA 
AATTCCAATA ACAACAACAG CAATCCATGT TCAGAACAAG ATATCCTTAC ACAAGGTGTT 
ACAAGCACAG CTGCAGATCC TGGGCCATCA AAGCCCAGAA GAGCACAGAG GCCCAATTCT 
CTGGATCTTT CAGCCACAAA TATCCTGGAT GGCAGCAGTA TACAGAGTGA GTCAACACAA 
GATGGCAAAT CAGGATCAGG TGAAAAGATC AAGAGACGTG TGAAAACTCC ATACTCTCTT 
AAGCGGTGGC GCCCGTCCAC CTGGGTCATC TCCACCGAGC CGCTGGACTG TGAGGTCAAC 
AACAATGGCA GTGACAGGGC AGTCCATTCT AAATCTAGCA CTGCTGTGTA CCTTGCAGAG 
GGAGGCACTG CCACGACCAC AGTGTCTAAA GATATAGGAA TGAATTGTCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bmpr2 ( NM_007561.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031587.1 Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), mRNA.

Price & Availability↑

CloneID	OMu20171
Clone ID Related Accession (Same CDS sequence)	NM_007561.4
Accession Version	NM_007561.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3117bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-26
Organism	Mus musculus(house mouse)
Product	bone morphogenetic protein receptor type-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK149385.1, AK138715.1, AK148180.1, AC125377.5 and BM940059.1. On Mar 20, 2013 this sequence version replaced NM_007561.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF003942.1, U78048.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTTCCT CGCTGCATCG GCCCTTTCGG GTGCCCTGGC TGCTATGGGC CGTCCTGCTG 
GTCAGCACTA CGGCTGCTTC TCAGAATCAA GAACGGCTGT GTGCATTTAA AGATCCATAT 
CAACAAGATC TTGGGATAGG TGAGAGTCGA ATCTCTCATG AAAATGGGAC AATATTATGT 
TCCAAAGGGA GCACGTGTTA TGGTCTGTGG GAGAAATCAA AAGGGGACAT CAATCTTGTG 
AAACAAGGAT GTTGGTCTCA CATCGGTGAT CCCCAAGAGT GCCACTATGA AGAGTGTGTA 
GTAACTACCA CCCCACCCTC AATTCAGAAT GGAACGTACC GCTTTTGCTG CTGTAGTACA 
GATTTATGTA ATGTCAACTT TACTGAGAAC TTTCCACCCC CTGACACAAC ACCACTCAGT 
CCACCTCATT CATTTAATCG AGATGAAACG ATAATCATTG CTTTGGCATC AGTTTCTGTG 
TTAGCTGTTT TGATAGTCGC CTTATGTTTT GGATACAGAA TGTTGACAGG AGACCGGAAA 
CAGGGTCTTC ACAGCATGAA CATGATGGAG GCGGCAGCAG CAGAGCCCTC CCTTGACCTG 
GATAACCTGA AGCTGCTGGA GCTGATTGGA CGGGGTCGAT ACGGAGCAGT ATATAAAGGT 
TCCTTGGATG AGCGTCCAGT TGCTGTAAAA GTATTTTCTT TTGCAAACCG TCAGAATTTT 
ATAAATGAAA AAAACATTTA CAGAGTGCCT TTGATGGAAC ATGACAACAT TGCTCGCTTC 
ATAGTTGGAG ACGAGAGGCT CACTGCAGAC GGCCGCATGG AGTATTTGCT TGTGATGGAG 
TATTATCCCA ATGGATCTCT GTGCAAATAT CTGAGTCTCC ACACAAGTGA TTGGGTAAGC 
TCTTGCCGTC TGGCTCATTC TGTGACTAGA GGACTGGCTT ATCTTCACAC AGAATTACCA 
CGAGGAGATC ATTATAAACC CGCAATCTCC CACCGAGATT TAAACAGCAG GAATGTCCTG 
GTAAAGAATG ACGGCGCGTG TGTTATCAGT GACTTTGGTT TATCCATGAG GCTAACTGGA 
AATCGGCTGG TGCGCCCAGG GGAAGAAGAT AATGCGGCTA TAAGTGAGGT TGGCACAATT 
CGCTATATGG CACCAGAAGT GCTAGAAGGA GCTGTGAACC TGAGGGACTG TGAGTCAGCT 
CTGAAGCAAG TGGACATGTA TGCGCTTGGA CTCATCTACT GGGAGGTGTT TATGAGGTGT 
ACAGACCTCT TCCCAGGTGA ATCTGTACCA GATTACCAGA TGGCTTTTCA GACAGAAGTT 
GGAAACCATC CCACATTTGA GGATATGCAG GTTCTTGTGT CCAGAGAGAA GCAGAGACCC 
AAGTTCCCAG AAGCCTGGAA AGAAAATAGC CTGGCAGTGA GGTCACTCAA GGAAACAATT 
GAAGACTGCT GGGACCAGGA TGCAGAGGCT CGGCTCACTG CACAGTGTGC TGAGGAGAGG 
ATGGCTGAAC TCATGATGAT ATGGGAGAGA AACAAGTCTG TGAGCCCAAC GGTCAACCCA 
ATGTCAACTG CTATGCAGAA TGAACGCAAC CTGTCACATA ATAGGCGTGT GCCAAAAATC 
GGGCCTTACC CAGATTATTC CTCTTCCTCA TATATTGAAG ACTCTATCCA TCATACTGAC 
AGCATTGTGA AGAATATTTC CTCTGAGCAT TCGATGTCCA GCACACCATT GACAATAGGA 
GAAAAGAATC GAAATTCAAT TAATTATGAA CGACAGCAAG CACAAGCTCG AATCCCTAGC 
CCAGAAACAA GCGTCACAAG CCTGTCCACA AACACAACCA CCACAAACAC CACCGGCCTC 
ACTCCAAGTA CTGGCATGAC CACTATATCT GAGATGCCAT ACCCAGATGA GACACATTTG 
CACGCCACAA ATGTTGCACA GTCAATCGGG CCAACCCCTG TCTGCTTACA GCTGACAGAA 
GAAGACTTGG AGACTAATAA GCTAGATCCA AAAGAAGTTG ATAAGAACCT CAAGGAAAGC 
TCTGATGAGA ATCTCATGGA GCATTCTCTG AAGCAGTTCA GTGGGCCAGA CCCATTGAGC 
AGTACCAGTT CTAGCTTGCT TTATCCACTC ATAAAGCTCG CAGTGGAAGT GACTGGACAA 
CAGGACTTCA CACAGGCTGC AAATGGGCAA GCATGTTTAA TTCCTGATGT TCCACCTGCT 
CAGATCTATC CTCTCCCTAA GCAACAGAAC CTTCCTAAGA GACCTACTAG TTTGCCTTTG 
AACACCAAAA ATTCAACAAA AGAACCCCGG CTAAAATTTG GCAACAAGCA CAAATCAAAC 
TTGAAACAAG TAGAAACTGG AGTTGCCAAG ATGAATACAA TCAATGCAGC AGAGCCTCAT 
GTGGTGACAG TAACTATGAA TGGTGTGGCA GGTAGAAGCC ACAATGTTAA TTCCCATGCT 
GCCACAACCC AGTATGCCAA TGGCGCAGTG CCAGCTGGCC AGGCAGCCAA CATAGTGGCA 
CATAGGTCCC AAGAAATGCT GCAGAATCAA TTTATTGGTG AGGATACCAG GCTGAATATC 
AATTCCAGTC CTGATGAGCA TGAACCTTTA CTGAGACGAG AGCAACAGGC TGGCCATGAT 
GAAGGGGTTC TGGATCGTTT GGTAGATAGG AGGGAACGGC CATTAGAAGG TGGCCGAACA 
AATTCCAATA ACAACAACAG CAATCCATGT TCAGAACAAG ATATCCTTAC ACAAGGTGTT 
ACAAGCACAG CTGCAGATCC TGGGCCATCA AAGCCCAGAA GAGCACAGAG GCCCAATTCT 
CTGGATCTTT CAGCCACAAA TATCCTGGAT GGCAGCAGTA TACAGATAGG TGAGTCAACA 
CAAGATGGCA AATCAGGATC AGGTGAAAAG ATCAAGAGAC GTGTGAAAAC TCCATACTCT 
CTTAAGCGGT GGCGCCCGTC CACCTGGGTC ATCTCCACCG AGCCGCTGGA CTGTGAGGTC 
AACAACAATG GCAGTGACAG GGCAGTCCAT TCTAAATCTA GCACTGCTGT GTACCTTGCA 
GAGGGAGGCA CTGCCACGAC CACAGTGTCT AAAGATATAG GAATGAATTG TCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031587.1
CDS	375..3491
Translation	MTSSLHRPFRVPWLLWAVLLVSTTAASQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDETIIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAAAEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERLTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGACVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEVFMRCTDLFPGESVPDYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSIVKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDETHLHATNVAQSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLSSTSSSLLYPLIKLAVEVTGQQDFTQAANGQACLIPDVPPAQIYPLPKQQNLPKRPTSLPLNTKNSTKEPRLKFGNKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRSHNVNSHAATTQYANGAVPAGQAANIVAHRSQEMLQNQFIGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRTNSNNNNSNPCSEQDILTQGVTSTAADPGPSKPRRAQRPNSLDLSATNILDGSSIQIGESTQDGKSGSGEKIKRRVKTPYSLKRWRPSTWVISTEPLDCEVNNNGSDRAVHSKSSTAVYLAEGGTATTTVSKDIGMNCL

Target ORF information:

RefSeq Version	NM_007561.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007561.4

ORF Insert Sequence:

ATGACTTCCT CGCTGCATCG GCCCTTTCGG GTGCCCTGGC TGCTATGGGC CGTCCTGCTG 
GTCAGCACTA CGGCTGCTTC TCAGAATCAA GAACGGCTGT GTGCATTTAA AGATCCATAT 
CAACAAGATC TTGGGATAGG TGAGAGTCGA ATCTCTCATG AAAATGGGAC AATATTATGT 
TCCAAAGGGA GCACGTGTTA TGGTCTGTGG GAGAAATCAA AAGGGGACAT CAATCTTGTG 
AAACAAGGAT GTTGGTCTCA CATCGGTGAT CCCCAAGAGT GCCACTATGA AGAGTGTGTA 
GTAACTACCA CCCCACCCTC AATTCAGAAT GGAACGTACC GCTTTTGCTG CTGTAGTACA 
GATTTATGTA ATGTCAACTT TACTGAGAAC TTTCCACCCC CTGACACAAC ACCACTCAGT 
CCACCTCATT CATTTAATCG AGATGAAACG ATAATCATTG CTTTGGCATC AGTTTCTGTG 
TTAGCTGTTT TGATAGTCGC CTTATGTTTT GGATACAGAA TGTTGACAGG AGACCGGAAA 
CAGGGTCTTC ACAGCATGAA CATGATGGAG GCGGCAGCAG CAGAGCCCTC CCTTGACCTG 
GATAACCTGA AGCTGCTGGA GCTGATTGGA CGGGGTCGAT ACGGAGCAGT ATATAAAGGT 
TCCTTGGATG AGCGTCCAGT TGCTGTAAAA GTATTTTCTT TTGCAAACCG TCAGAATTTT 
ATAAATGAAA AAAACATTTA CAGAGTGCCT TTGATGGAAC ATGACAACAT TGCTCGCTTC 
ATAGTTGGAG ACGAGAGGCT CACTGCAGAC GGCCGCATGG AGTATTTGCT TGTGATGGAG 
TATTATCCCA ATGGATCTCT GTGCAAATAT CTGAGTCTCC ACACAAGTGA TTGGGTAAGC 
TCTTGCCGTC TGGCTCATTC TGTGACTAGA GGACTGGCTT ATCTTCACAC AGAATTACCA 
CGAGGAGATC ATTATAAACC CGCAATCTCC CACCGAGATT TAAACAGCAG GAATGTCCTG 
GTAAAGAATG ACGGCGCGTG TGTTATCAGT GACTTTGGTT TATCCATGAG GCTAACTGGA 
AATCGGCTGG TGCGCCCAGG GGAAGAAGAT AATGCGGCTA TAAGTGAGGT TGGCACAATT 
CGCTATATGG CACCAGAAGT GCTAGAAGGA GCTGTGAACC TGAGGGACTG TGAGTCAGCT 
CTGAAGCAAG TGGACATGTA TGCGCTTGGA CTCATCTACT GGGAGGTGTT TATGAGGTGT 
ACAGACCTCT TCCCAGGTGA ATCTGTACCA GATTACCAGA TGGCTTTTCA GACAGAAGTT 
GGAAACCATC CCACATTTGA GGATATGCAG GTTCTTGTGT CCAGAGAGAA GCAGAGACCC 
AAGTTCCCAG AAGCCTGGAA AGAAAATAGC CTGGCAGTGA GGTCACTCAA GGAAACAATT 
GAAGACTGCT GGGACCAGGA TGCAGAGGCT CGGCTCACTG CACAGTGTGC TGAGGAGAGG 
ATGGCTGAAC TCATGATGAT ATGGGAGAGA AACAAGTCTG TGAGCCCAAC GGTCAACCCA 
ATGTCAACTG CTATGCAGAA TGAACGCAAC CTGTCACATA ATAGGCGTGT GCCAAAAATC 
GGGCCTTACC CAGATTATTC CTCTTCCTCA TATATTGAAG ACTCTATCCA TCATACTGAC 
AGCATTGTGA AGAATATTTC CTCTGAGCAT TCGATGTCCA GCACACCATT GACAATAGGA 
GAAAAGAATC GAAATTCAAT TAATTATGAA CGACAGCAAG CACAAGCTCG AATCCCTAGC 
CCAGAAACAA GCGTCACAAG CCTGTCCACA AACACAACCA CCACAAACAC CACCGGCCTC 
ACTCCAAGTA CTGGCATGAC CACTATATCT GAGATGCCAT ACCCAGATGA GACACATTTG 
CACGCCACAA ATGTTGCACA GTCAATCGGG CCAACCCCTG TCTGCTTACA GCTGACAGAA 
GAAGACTTGG AGACTAATAA GCTAGATCCA AAAGAAGTTG ATAAGAACCT CAAGGAAAGC 
TCTGATGAGA ATCTCATGGA GCATTCTCTG AAGCAGTTCA GTGGGCCAGA CCCATTGAGC 
AGTACCAGTT CTAGCTTGCT TTATCCACTC ATAAAGCTCG CAGTGGAAGT GACTGGACAA 
CAGGACTTCA CACAGGCTGC AAATGGGCAA GCATGTTTAA TTCCTGATGT TCCACCTGCT 
CAGATCTATC CTCTCCCTAA GCAACAGAAC CTTCCTAAGA GACCTACTAG TTTGCCTTTG 
AACACCAAAA ATTCAACAAA AGAACCCCGG CTAAAATTTG GCAACAAGCA CAAATCAAAC 
TTGAAACAAG TAGAAACTGG AGTTGCCAAG ATGAATACAA TCAATGCAGC AGAGCCTCAT 
GTGGTGACAG TAACTATGAA TGGTGTGGCA GGTAGAAGCC ACAATGTTAA TTCCCATGCT 
GCCACAACCC AGTATGCCAA TGGCGCAGTG CCAGCTGGCC AGGCAGCCAA CATAGTGGCA 
CATAGGTCCC AAGAAATGCT GCAGAATCAA TTTATTGGTG AGGATACCAG GCTGAATATC 
AATTCCAGTC CTGATGAGCA TGAACCTTTA CTGAGACGAG AGCAACAGGC TGGCCATGAT 
GAAGGGGTTC TGGATCGTTT GGTAGATAGG AGGGAACGGC CATTAGAAGG TGGCCGAACA 
AATTCCAATA ACAACAACAG CAATCCATGT TCAGAACAAG ATATCCTTAC ACAAGGTGTT 
ACAAGCACAG CTGCAGATCC TGGGCCATCA AAGCCCAGAA GAGCACAGAG GCCCAATTCT 
CTGGATCTTT CAGCCACAAA TATCCTGGAT GGCAGCAGTA TACAGATAGG TGAGTCAACA 
CAAGATGGCA AATCAGGATC AGGTGAAAAG ATCAAGAGAC GTGTGAAAAC TCCATACTCT 
CTTAAGCGGT GGCGCCCGTC CACCTGGGTC ATCTCCACCG AGCCGCTGGA CTGTGAGGTC 
AACAACAATG GCAGTGACAG GGCAGTCCAT TCTAAATCTA GCACTGCTGT GTACCTTGCA 
GAGGGAGGCA CTGCCACGAC CACAGTGTCT AAAGATATAG GAATGAATTG TCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bmpr2 ( XM_006495633.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495696.1 Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), transcript variant X1, mRNA.

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CloneID	OMu27218
Clone ID Related Accession (Same CDS sequence)	XM_006495633.2 , XM_006495633.1
Accession Version	XM_006495633.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	bone morphogenetic protein receptor type-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTTCCT CGCTGCATCG GCCCTTTCGG GTGCCCTGGC TGCTATGGGC CGTCCTGCTG 
GTCAGCACTA CGGCTGCTTC TCAGAATCAA GAACGGCTGT GTGCATTTAA AGATCCATAT 
CAACAAGATC TTGGGATAGG TGAGAGTCGA ATCTCTCATG AAAATGGGAC AATATTATGT 
TCCAAAGGGA GCACGTGTTA TGGTCTGTGG GAGAAATCAA AAGGGGACAT CAATCTTGTG 
AAACAAGGAT GTTGGTCTCA CATCGGTGAT CCCCAAGAGT GCCACTATGA AGAGTGTGTA 
GTAACTACCA CCCCACCCTC AATTCAGAAT GGAACGTACC GCTTTTGCTG CTGTAGTACA 
GATTTATGTA ATGTCAACTT TACTGAGAAC TTTCCACCCC CTGACACAAC ACCACTCAGT 
CCACCTCATT CATTTAATCG AGATGAAACG ATAATCATTG CTTTGGCATC AGTTTCTGTG 
TTAGCTGTTT TGATAGTCGC CTTATGTTTT GGATACAGAA TGTTGACAGG AGACCGGAAA 
CAGGGTCTTC ACAGCATGAA CATGATGGAG GCGGCAGCAG CAGAGCCCTC CCTTGACCTG 
GATAACCTGA AGCTGCTGGA GCTGATTGGA CGGGGTCGAT ACGGAGCAGT ATATAAAGGT 
TCCTTGGATG AGCGTCCAGT TGCTGTAAAA GTATTTTCTT TTGCAAACCG TCAGAATTTT 
ATAAATGAAA AAAACATTTA CAGAGTGCCT TTGATGGAAC ATGACAACAT TGCTCGCTTC 
ATAGTTGGAG ACGAGAGGCT CACTGCAGAC GGCCGCATGG AGTATTTGCT TGTGATGGAG 
TATTATCCCA ATGGATCTCT GTGCAAATAT CTGAGTCTCC ACACAAGTGA TTGGGTAAGC 
TCTTGCCGTC TGGCTCATTC TGTGACTAGA GGACTGGCTT ATCTTCACAC AGAATTACCA 
CGAGGAGATC ATTATAAACC CGCAATCTCC CACCGAGATT TAAACAGCAG GAATGTCCTG 
GTAAAGAATG ACGGCGCGTG TGTTATCAGT GACTTTGGTT TATCCATGAG GCTAACTGGA 
AATCGGCTGG TGCGCCCAGG GGAAGAAGAT AATGCGGCTA TAAGTGAGGT TGGCACAATT 
CGCTATATGG CACCAGAAGT GCTAGAAGGA GCTGTGAACC TGAGGGACTG TGAGTCAGCT 
CTGAAGCAAG TGGACATGTA TGCGCTTGGA CTCATCTACT GGGAGGTGTT TATGAGGTGT 
ACAGACCTCT TCCCAGGTGA ATCTGTACCA GATTACCAGA TGGCTTTTCA GACAGAAGTT 
GGAAACCATC CCACATTTGA GGATATGCAG GTTCTTGTGT CCAGAGAGAA GCAGAGACCC 
AAGTTCCCAG AAGCCTGGAA AGAAAATAGC CTGGCAGTGA GGTCACTCAA GGAAACAATT 
GAAGACTGCT GGGACCAGGA TGCAGAGGCT CGGCTCACTG CACAGTGTGC TGAGGAGAGG 
ATGGCTGAAC TCATGATGAT ATGGGAGAGA AACAAGTCTG TGAGCCCAAC GGTCAACCCA 
ATGTCAACTG CTATGCAGAA TGAACGCAAC CTGTCACATA ATAGGCGTGT GCCAAAAATC 
GGGCCTTACC CAGATTATTC CTCTTCCTCA TATATTGAAG ACTCTATCCA TCATACTGAC 
AGCATTGTGA AGAATATTTC CTCTGAGCAT TCGATGTCCA GCACACCATT GACAATAGGA 
GAAAAGAATC GAAATTCAAT TAATTATGAA CGACAGCAAG CACAAGCTCG AATCCCTAGC 
CCAGAAACAA GCGTCACAAG CCTGTCCACA AACACAACCA CCACAAACAC CACCGGCCTC 
ACTCCAAGTA CTGGCATGAC CACTATATCT GAGATGCCAT ACCCAGATGA GACACATTTG 
CACGCCACAA ATGTTGCACA GTCAATCGGG CCAACCCCTG TCTGCTTACA GCTGACAGAA 
GAAGACTTGG AGACTAATAA GCTAGATCCA AAAGAAGTTG ATAAGAACCT CAAGGAAAGC 
TCTGATGAGA ATCTCATGGA GCATTCTCTG AAGCAGTTCA GTGGGCCAGA CCCATTGAGC 
AGTACCAGTT CTAGCTTGCT TTATCCACTC ATAAAGCTCG CAGTGGAAGT GACTGGACAA 
CAGGACTTCA CACAGGCTGC AAATGGGCAA GCATGTTTAA TTCCTGATGT TCCACCTGCT 
CAGATCTATC CTCTCCCTAA GCAACAGAAC CTTCCTAAGA GACCTACTAG TTTGCCTTTG 
AACACCAAAA ATTCAACAAA AGAACCCCGG CTAAAATTTG GCAACAAGCA CAAATCAAAC 
TTGAAACAAG TAGAAACTGG AGTTGCCAAG ATGAATACAA TCAATGCAGC AGAGCCTCAT 
GTGGTGACAG TAACTATGAA TGGTGTGGCA GGTAGAAGCC ACAATGTTAA TTCCCATGCT 
GCCACAACCC AGTATGCCAA TGGCGCAGTG CCAGCTGGCC AGGCAGCCAA CATAGTGGCA 
CATAGGTCCC AAGAAATGCT GCAGAATCAA TTTATTGGTG AGGATACCAG GCTGAATATC 
AATTCCAGTC CTGATGAGCA TGAACCTTTA CTGAGACGAG AGCAACAGGC TGGCCATGAT 
GAAGGGGTTC TGGATCGTTT GGTAGATAGG AGGGAACGGC CATTAGAAGG TGGCCGAACA 
AATTCCAATA ACAACAACAG CAATCCATGT TCAGAACAAG ATATCCTTAC ACAAGGTGTT 
ACAAGCACAG CTGCAGATCC TGGGCCATCA AAGCCCAGAA GAGCACAGAG GCCCAATTCT 
CTGGATCTTT CAGCCACAAA TATCCTGGAT GGCAGCAGTA TACAGAGTGA GTCAACACAA 
GATGGCAAAT CAGGATCAGG TGAAAAGATC AAGAGACGTG TGAAAACTCC ATACTCTCTT 
AAGCGGTGGC GCCCGTCCAC CTGGGTCATC TCCACCGAGC CGCTGGACTG TGAGGTCAAC 
AACAATGGCA GTGACAGGGC AGTCCATTCT AAATCTAGCA CTGCTGTGTA CCTTGCAGAG 
GGAGGCACTG CCACGACCAC AGTGTCTAAA GATATAGGAA TGAATTGTCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495696.1
CDS	384..3497
Translation	MTSSLHRPFRVPWLLWAVLLVSTTAASQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDETIIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAAAEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERLTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGACVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEVFMRCTDLFPGESVPDYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSIVKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDETHLHATNVAQSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLSSTSSSLLYPLIKLAVEVTGQQDFTQAANGQACLIPDVPPAQIYPLPKQQNLPKRPTSLPLNTKNSTKEPRLKFGNKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRSHNVNSHAATTQYANGAVPAGQAANIVAHRSQEMLQNQFIGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRTNSNNNNSNPCSEQDILTQGVTSTAADPGPSKPRRAQRPNSLDLSATNILDGSSIQSESTQDGKSGSGEKIKRRVKTPYSLKRWRPSTWVISTEPLDCEVNNNGSDRAVHSKSSTAVYLAEGGTATTTVSKDIGMNCL

Target ORF information:

RefSeq Version	XM_006495633.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495633.1

ORF Insert Sequence:

ATGACTTCCT CGCTGCATCG GCCCTTTCGG GTGCCCTGGC TGCTATGGGC CGTCCTGCTG 
GTCAGCACTA CGGCTGCTTC TCAGAATCAA GAACGGCTGT GTGCATTTAA AGATCCATAT 
CAACAAGATC TTGGGATAGG TGAGAGTCGA ATCTCTCATG AAAATGGGAC AATATTATGT 
TCCAAAGGGA GCACGTGTTA TGGTCTGTGG GAGAAATCAA AAGGGGACAT CAATCTTGTG 
AAACAAGGAT GTTGGTCTCA CATCGGTGAT CCCCAAGAGT GCCACTATGA AGAGTGTGTA 
GTAACTACCA CCCCACCCTC AATTCAGAAT GGAACGTACC GCTTTTGCTG CTGTAGTACA 
GATTTATGTA ATGTCAACTT TACTGAGAAC TTTCCACCCC CTGACACAAC ACCACTCAGT 
CCACCTCATT CATTTAATCG AGATGAAACG ATAATCATTG CTTTGGCATC AGTTTCTGTG 
TTAGCTGTTT TGATAGTCGC CTTATGTTTT GGATACAGAA TGTTGACAGG AGACCGGAAA 
CAGGGTCTTC ACAGCATGAA CATGATGGAG GCGGCAGCAG CAGAGCCCTC CCTTGACCTG 
GATAACCTGA AGCTGCTGGA GCTGATTGGA CGGGGTCGAT ACGGAGCAGT ATATAAAGGT 
TCCTTGGATG AGCGTCCAGT TGCTGTAAAA GTATTTTCTT TTGCAAACCG TCAGAATTTT 
ATAAATGAAA AAAACATTTA CAGAGTGCCT TTGATGGAAC ATGACAACAT TGCTCGCTTC 
ATAGTTGGAG ACGAGAGGCT CACTGCAGAC GGCCGCATGG AGTATTTGCT TGTGATGGAG 
TATTATCCCA ATGGATCTCT GTGCAAATAT CTGAGTCTCC ACACAAGTGA TTGGGTAAGC 
TCTTGCCGTC TGGCTCATTC TGTGACTAGA GGACTGGCTT ATCTTCACAC AGAATTACCA 
CGAGGAGATC ATTATAAACC CGCAATCTCC CACCGAGATT TAAACAGCAG GAATGTCCTG 
GTAAAGAATG ACGGCGCGTG TGTTATCAGT GACTTTGGTT TATCCATGAG GCTAACTGGA 
AATCGGCTGG TGCGCCCAGG GGAAGAAGAT AATGCGGCTA TAAGTGAGGT TGGCACAATT 
CGCTATATGG CACCAGAAGT GCTAGAAGGA GCTGTGAACC TGAGGGACTG TGAGTCAGCT 
CTGAAGCAAG TGGACATGTA TGCGCTTGGA CTCATCTACT GGGAGGTGTT TATGAGGTGT 
ACAGACCTCT TCCCAGGTGA ATCTGTACCA GATTACCAGA TGGCTTTTCA GACAGAAGTT 
GGAAACCATC CCACATTTGA GGATATGCAG GTTCTTGTGT CCAGAGAGAA GCAGAGACCC 
AAGTTCCCAG AAGCCTGGAA AGAAAATAGC CTGGCAGTGA GGTCACTCAA GGAAACAATT 
GAAGACTGCT GGGACCAGGA TGCAGAGGCT CGGCTCACTG CACAGTGTGC TGAGGAGAGG 
ATGGCTGAAC TCATGATGAT ATGGGAGAGA AACAAGTCTG TGAGCCCAAC GGTCAACCCA 
ATGTCAACTG CTATGCAGAA TGAACGCAAC CTGTCACATA ATAGGCGTGT GCCAAAAATC 
GGGCCTTACC CAGATTATTC CTCTTCCTCA TATATTGAAG ACTCTATCCA TCATACTGAC 
AGCATTGTGA AGAATATTTC CTCTGAGCAT TCGATGTCCA GCACACCATT GACAATAGGA 
GAAAAGAATC GAAATTCAAT TAATTATGAA CGACAGCAAG CACAAGCTCG AATCCCTAGC 
CCAGAAACAA GCGTCACAAG CCTGTCCACA AACACAACCA CCACAAACAC CACCGGCCTC 
ACTCCAAGTA CTGGCATGAC CACTATATCT GAGATGCCAT ACCCAGATGA GACACATTTG 
CACGCCACAA ATGTTGCACA GTCAATCGGG CCAACCCCTG TCTGCTTACA GCTGACAGAA 
GAAGACTTGG AGACTAATAA GCTAGATCCA AAAGAAGTTG ATAAGAACCT CAAGGAAAGC 
TCTGATGAGA ATCTCATGGA GCATTCTCTG AAGCAGTTCA GTGGGCCAGA CCCATTGAGC 
AGTACCAGTT CTAGCTTGCT TTATCCACTC ATAAAGCTCG CAGTGGAAGT GACTGGACAA 
CAGGACTTCA CACAGGCTGC AAATGGGCAA GCATGTTTAA TTCCTGATGT TCCACCTGCT 
CAGATCTATC CTCTCCCTAA GCAACAGAAC CTTCCTAAGA GACCTACTAG TTTGCCTTTG 
AACACCAAAA ATTCAACAAA AGAACCCCGG CTAAAATTTG GCAACAAGCA CAAATCAAAC 
TTGAAACAAG TAGAAACTGG AGTTGCCAAG ATGAATACAA TCAATGCAGC AGAGCCTCAT 
GTGGTGACAG TAACTATGAA TGGTGTGGCA GGTAGAAGCC ACAATGTTAA TTCCCATGCT 
GCCACAACCC AGTATGCCAA TGGCGCAGTG CCAGCTGGCC AGGCAGCCAA CATAGTGGCA 
CATAGGTCCC AAGAAATGCT GCAGAATCAA TTTATTGGTG AGGATACCAG GCTGAATATC 
AATTCCAGTC CTGATGAGCA TGAACCTTTA CTGAGACGAG AGCAACAGGC TGGCCATGAT 
GAAGGGGTTC TGGATCGTTT GGTAGATAGG AGGGAACGGC CATTAGAAGG TGGCCGAACA 
AATTCCAATA ACAACAACAG CAATCCATGT TCAGAACAAG ATATCCTTAC ACAAGGTGTT 
ACAAGCACAG CTGCAGATCC TGGGCCATCA AAGCCCAGAA GAGCACAGAG GCCCAATTCT 
CTGGATCTTT CAGCCACAAA TATCCTGGAT GGCAGCAGTA TACAGAGTGA GTCAACACAA 
GATGGCAAAT CAGGATCAGG TGAAAAGATC AAGAGACGTG TGAAAACTCC ATACTCTCTT 
AAGCGGTGGC GCCCGTCCAC CTGGGTCATC TCCACCGAGC CGCTGGACTG TGAGGTCAAC 
AACAATGGCA GTGACAGGGC AGTCCATTCT AAATCTAGCA CTGCTGTGTA CCTTGCAGAG 
GGAGGCACTG CCACGACCAC AGTGTCTAAA GATATAGGAA TGAATTGTCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Bone morphogenetic protein receptors and signal transduction.
Journal of biochemistry147(1)35-51(2010 Jan)
Miyazono K,Kamiya Y,Morikawa M

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Bmpr2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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