Bdkrb1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bdkrb1
Entrez Gene ID	12061
Full Name	bradykinin receptor, beta 1
Synonyms	B1BKR,B1R,BKR1,BRADYB1,Bdkrb
General protein information	Preferred Names bradykinin receptor, beta 1 Names B1 bradykinin receptor BK-1 receptor kinin B1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 E

mRNA and Protein(s)

mRNA	Protein	Name
NM_007539.2	NP_031565.1	B1 bradykinin receptor
NM_007539.3	NP_031565.1	B1 bradykinin receptor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BDKRB1	NP_001103469.1
Canis lupus familiaris (dog)	BDKRB1	NP_001014306.1
Pan troglodytes (chimpanzee)	BDKRB1	XP_003314558.1
Mus musculus (house mouse)	Bdkrb1	NP_031565.1
Homo sapiens (human)	BDKRB1	NP_000701.2
Rattus norvegicus (Norway rat)	Bdkrb1	NP_110478.1
Gallus gallus (chicken)	BDKRB1	NP_001074189.1

Gene Ontology
Bibliography

Related articles in PubMed

Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg
Sodhi CP, Wohlford-Lenane C, Yamaguchi Y, Prindle T, Fulton WB, Wang S, McCray PB Jr., Chappell M, Hackam DJ, Jia H
American journal of physiology. Lung cellular and molecular physiology314(1)L17-L31(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

study revealed that TRPA1 positively modulates the mechanical hyperalgesia induced by B1 receptor activation in the spinal cord and that the classical GPCR downstream molecules
Title: The transient receptor potential ankyrin-1 mediates mechanical hyperalgesia induced by the activation of B

Host kinin B1 receptor plays a protective role against melanoma progression.
Title: Host kinin B1 receptor plays a protective role against melanoma progression.

Kinin B1R contributes to acute gouty attacks, including the ones facilitated by ACEi.
Title: The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents.

Kinin B1 receptor deletion affects bone healing in type 1 diabetic mice with femoral defects.
Title: Kinin B1 Receptor Deletion Affects Bone Healing in Type 1 Diabetic Mice.

Studied nitric oxide (NO) release, L-arginine (L-Arg) uptake and the expression of the cationic amino acid transporter (CAT) -1 in endothelial cells obtained from B1 receptor knockout (B1-/-) and wild type (WT) mice.
Title: L-Arginine Transport and Nitric Oxide Production in Kinin Receptor B1-/- Endothelial Cells.

The following Bdkrb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bdkrb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu20388	NM_007539.3 Latest version!	Mus musculus bradykinin receptor, beta 1 (Bdkrb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
View Old Accession Versions >>
OMu20388	NM_007539.2	Mus musculus bradykinin receptor, beta 1 (Bdkrb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bdkrb1 ( NM_007539.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031565.1 Mus musculus bradykinin receptor, beta 1 (Bdkrb1), mRNA.

Price & Availability↑

CloneID	OMu20388
Clone ID Related Accession (Same CDS sequence)	NM_007539.2 , NM_007539.3
Accession Version	NM_007539.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2014-05-10
Organism	Mus musculus(House mouse)
Product	B1 bradykinin receptor
Comment

ATGGCGTCCC AGGCCTCGCT GAAGCTACAG CCTTCTAACC AAAGCCAGCA GGCCCCTCCC 
AACATCACCT CCTGCGAGGG CGCCCCGGAA GCCTGGGATC TGCTGTGTCG GGTGCTGCCA 
GGGTTTGTCA TCACTGTCTG TTTCTTTGGC CTCCTGGGGA ACCTTTTAGT CCTGTCCTTC 
TTCCTTTTGC CTTGGCGACG ATGGTGGCAG CAGCGGCGGC AGCGCCTAAC CATAGCAGAA 
ATCTACCTGG CTAACTTGGC AGCTTCTGAT CTGGTGTTTG TGCTGGGCCT GCCCTTCTGG 
GCAGAGAACG TTGGGAACCG TTTCAACTGG CCCTTTGGAA GTGACCTCTG CCGGGTGGTC 
AGCGGGGTCA TCAAGGCCAA CCTGTTCATC AGCATCTTCC TGGTGGTGGC CATCAGTCAG 
GACCGCTACA GGTTGCTGGT ATACCCCATG ACCAGCTGGG GGAACCGGCG GCGACGGCAA 
GCCCAAGTGA CCTGCCTGCT CATCTGGGTA GCTGGGGGCC TCTTGAGCAC CCCCACGTTC 
CTTCTGCGTT CCGTCAAAGT CGTCCCTGAT CTGAACATCT CTGCCTGCAT CCTGCTTTTC 
CCCCACGAAG CTTGGCACTT TGTAAGGATG GTGGAGTTGA ACGTTTTGGG TTTCCTCCTC 
CCATTGGCTG CCATCCTCTA CTTCAACTTT CACATCCTGG CCTCCCTGAG AGGACAGAAG 
GAGGCCAGCA GAACCCGGTG TGGGGGACCC AAGGACAGCA AGACAATGGG GCTGATCCTC 
ACACTGGTAG CCTCCTTCCT GGTCTGCTGG GCCCCTTACC ACTTCTTTGC CTTCCTGGAT 
TTCCTGGTCC AGGTGAGAGT GATCCAGGAC TGCTTCTGGA AGGAGCTCAC AGACCTGGGC 
CTGCAGCTGG CCAACTTCTT TGCTTTTGTC AACAGCTGCC TGAACCCACT GATTTATGTC 
TTTGCAGGCC GGCTCTTTAA GACCAGGGTT CTGGGAACTT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031565.1
Translation	MASQASLKLQPSNQSQQAPPNITSCEGAPEAWDLLCRVLPGFVITVCFFGLLGNLLVLSFFLLPWRRWWQQRRQRLTIAEIYLANLAASDLVFVLGLPFWAENVGNRFNWPFGSDLCRVVSGVIKANLFISIFLVVAISQDRYRLLVYPMTSWGNRRRRQAQVTCLLIWVAGGLLSTPTFLLRSVKVVPDLNISACILLFPHEAWHFVRMVELNVLGFLLPLAAILYFNFHILASLRGQKEASRTRCGGPKDSKTMGLILTLVASFLVCWAPYHFFAFLDFLVQVRVIQDCFWKELTDLGLQLANFFAFVNSCLNPLIYVFAGRLFKTRVLGTL

Target ORF information:

RefSeq Version	NM_007539.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus bradykinin receptor, beta 1 (Bdkrb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007539.2

ORF Insert Sequence:

ATGGCGTCCC AGGCCTCGCT GAAGCTACAG CCTTCTAACC AAAGCCAGCA GGCCCCTCCC 
AACATCACCT CCTGCGAGGG CGCCCCGGAA GCCTGGGATC TGCTGTGTCG GGTGCTGCCA 
GGGTTTGTCA TCACTGTCTG TTTCTTTGGC CTCCTGGGGA ACCTTTTAGT CCTGTCCTTC 
TTCCTTTTGC CTTGGCGACG ATGGTGGCAG CAGCGGCGGC AGCGCCTAAC CATAGCAGAA 
ATCTACCTGG CTAACTTGGC AGCTTCTGAT CTGGTGTTTG TGCTGGGCCT GCCCTTCTGG 
GCAGAGAACG TTGGGAACCG TTTCAACTGG CCCTTTGGAA GTGACCTCTG CCGGGTGGTC 
AGCGGGGTCA TCAAGGCCAA CCTGTTCATC AGCATCTTCC TGGTGGTGGC CATCAGTCAG 
GACCGCTACA GGTTGCTGGT ATACCCCATG ACCAGCTGGG GGAACCGGCG GCGACGGCAA 
GCCCAAGTGA CCTGCCTGCT CATCTGGGTA GCTGGGGGCC TCTTGAGCAC CCCCACGTTC 
CTTCTGCGTT CCGTCAAAGT CGTCCCTGAT CTGAACATCT CTGCCTGCAT CCTGCTTTTC 
CCCCACGAAG CTTGGCACTT TGTAAGGATG GTGGAGTTGA ACGTTTTGGG TTTCCTCCTC 
CCATTGGCTG CCATCCTCTA CTTCAACTTT CACATCCTGG CCTCCCTGAG AGGACAGAAG 
GAGGCCAGCA GAACCCGGTG TGGGGGACCC AAGGACAGCA AGACAATGGG GCTGATCCTC 
ACACTGGTAG CCTCCTTCCT GGTCTGCTGG GCCCCTTACC ACTTCTTTGC CTTCCTGGAT 
TTCCTGGTCC AGGTGAGAGT GATCCAGGAC TGCTTCTGGA AGGAGCTCAC AGACCTGGGC 
CTGCAGCTGG CCAACTTCTT TGCTTTTGTC AACAGCTGCC TGAACCCACT GATTTATGTC 
TTTGCAGGCC GGCTCTTTAA GACCAGGGTT CTGGGAACTT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bdkrb1 ( NM_007539.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031565.1 Mus musculus bradykinin receptor, beta 1 (Bdkrb1), mRNA.

Price & Availability↑

CloneID	OMu20388
Clone ID Related Accession (Same CDS sequence)	NM_007539.2 , NM_007539.3
Accession Version	NM_007539.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	B1 bradykinin receptor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC068459.9. On Dec 23, 2016 this sequence version replaced NM_007539.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGGCGTCCC AGGCCTCGCT GAAGCTACAG CCTTCTAACC AAAGCCAGCA GGCCCCTCCC 
AACATCACCT CCTGCGAGGG CGCCCCGGAA GCCTGGGATC TGCTGTGTCG GGTGCTGCCA 
GGGTTTGTCA TCACTGTCTG TTTCTTTGGC CTCCTGGGGA ACCTTTTAGT CCTGTCCTTC 
TTCCTTTTGC CTTGGCGACG ATGGTGGCAG CAGCGGCGGC AGCGCCTAAC CATAGCAGAA 
ATCTACCTGG CTAACTTGGC AGCTTCTGAT CTGGTGTTTG TGCTGGGCCT GCCCTTCTGG 
GCAGAGAACG TTGGGAACCG TTTCAACTGG CCCTTTGGAA GTGACCTCTG CCGGGTGGTC 
AGCGGGGTCA TCAAGGCCAA CCTGTTCATC AGCATCTTCC TGGTGGTGGC CATCAGTCAG 
GACCGCTACA GGTTGCTGGT ATACCCCATG ACCAGCTGGG GGAACCGGCG GCGACGGCAA 
GCCCAAGTGA CCTGCCTGCT CATCTGGGTA GCTGGGGGCC TCTTGAGCAC CCCCACGTTC 
CTTCTGCGTT CCGTCAAAGT CGTCCCTGAT CTGAACATCT CTGCCTGCAT CCTGCTTTTC 
CCCCACGAAG CTTGGCACTT TGTAAGGATG GTGGAGTTGA ACGTTTTGGG TTTCCTCCTC 
CCATTGGCTG CCATCCTCTA CTTCAACTTT CACATCCTGG CCTCCCTGAG AGGACAGAAG 
GAGGCCAGCA GAACCCGGTG TGGGGGACCC AAGGACAGCA AGACAATGGG GCTGATCCTC 
ACACTGGTAG CCTCCTTCCT GGTCTGCTGG GCCCCTTACC ACTTCTTTGC CTTCCTGGAT 
TTCCTGGTCC AGGTGAGAGT GATCCAGGAC TGCTTCTGGA AGGAGCTCAC AGACCTGGGC 
CTGCAGCTGG CCAACTTCTT TGCTTTTGTC AACAGCTGCC TGAACCCACT GATTTATGTC 
TTTGCAGGCC GGCTCTTTAA GACCAGGGTT CTGGGAACTT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031565.1
CDS	87..1091
Translation	MASQASLKLQPSNQSQQAPPNITSCEGAPEAWDLLCRVLPGFVITVCFFGLLGNLLVLSFFLLPWRRWWQQRRQRLTIAEIYLANLAASDLVFVLGLPFWAENVGNRFNWPFGSDLCRVVSGVIKANLFISIFLVVAISQDRYRLLVYPMTSWGNRRRRQAQVTCLLIWVAGGLLSTPTFLLRSVKVVPDLNISACILLFPHEAWHFVRMVELNVLGFLLPLAAILYFNFHILASLRGQKEASRTRCGGPKDSKTMGLILTLVASFLVCWAPYHFFAFLDFLVQVRVIQDCFWKELTDLGLQLANFFAFVNSCLNPLIYVFAGRLFKTRVLGTL

Target ORF information:

RefSeq Version	NM_007539.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus bradykinin receptor, beta 1 (Bdkrb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007539.3

ORF Insert Sequence:

ATGGCGTCCC AGGCCTCGCT GAAGCTACAG CCTTCTAACC AAAGCCAGCA GGCCCCTCCC 
AACATCACCT CCTGCGAGGG CGCCCCGGAA GCCTGGGATC TGCTGTGTCG GGTGCTGCCA 
GGGTTTGTCA TCACTGTCTG TTTCTTTGGC CTCCTGGGGA ACCTTTTAGT CCTGTCCTTC 
TTCCTTTTGC CTTGGCGACG ATGGTGGCAG CAGCGGCGGC AGCGCCTAAC CATAGCAGAA 
ATCTACCTGG CTAACTTGGC AGCTTCTGAT CTGGTGTTTG TGCTGGGCCT GCCCTTCTGG 
GCAGAGAACG TTGGGAACCG TTTCAACTGG CCCTTTGGAA GTGACCTCTG CCGGGTGGTC 
AGCGGGGTCA TCAAGGCCAA CCTGTTCATC AGCATCTTCC TGGTGGTGGC CATCAGTCAG 
GACCGCTACA GGTTGCTGGT ATACCCCATG ACCAGCTGGG GGAACCGGCG GCGACGGCAA 
GCCCAAGTGA CCTGCCTGCT CATCTGGGTA GCTGGGGGCC TCTTGAGCAC CCCCACGTTC 
CTTCTGCGTT CCGTCAAAGT CGTCCCTGAT CTGAACATCT CTGCCTGCAT CCTGCTTTTC 
CCCCACGAAG CTTGGCACTT TGTAAGGATG GTGGAGTTGA ACGTTTTGGG TTTCCTCCTC 
CCATTGGCTG CCATCCTCTA CTTCAACTTT CACATCCTGG CCTCCCTGAG AGGACAGAAG 
GAGGCCAGCA GAACCCGGTG TGGGGGACCC AAGGACAGCA AGACAATGGG GCTGATCCTC 
ACACTGGTAG CCTCCTTCCT GGTCTGCTGG GCCCCTTACC ACTTCTTTGC CTTCCTGGAT 
TTCCTGGTCC AGGTGAGAGT GATCCAGGAC TGCTTCTGGA AGGAGCTCAC AGACCTGGGC 
CTGCAGCTGG CCAACTTCTT TGCTTTTGTC AACAGCTGCC TGAACCCACT GATTTATGTC 
TTTGCAGGCC GGCTCTTTAA GACCAGGGTT CTGGGAACTT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg
American journal of physiology. Lung cellular and molecular physiology314(1)L17-L31(2018 Jan)
Sodhi CP,Wohlford-Lenane C,Yamaguchi Y,Prindle T,Fulton WB,Wang S,McCray PB Jr.,Chappell M,Hackam DJ,Jia H

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Bdkrb1 cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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