Bcl2l2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bcl2l2
Entrez Gene ID	12050
Full Name	BCL2-like 2
Synonyms	AW048834,Bcl-w,Gtrgal2,Gtrosa41,bclw,c98
General protein information	Preferred Names BCL2-like 2 Names bcl-2-like protein 2 apoptosis regulator Bcl-W bcl2-L-2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14 C2\|14 27.98 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006518457.3	XP_006518520.1	bcl-2-like protein 2 isoform X1
XM_006518458.3	XP_006518521.1	bcl-2-like protein 2 isoform X1
XM_006518458.2	XP_006518521.1	bcl-2-like protein 2 isoform X1
NM_007537.1	NP_031563.1	bcl-2-like protein 2
XM_006518457.4	XP_006518520.1	bcl-2-like protein 2 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	BCL2L2	XP_003314309.1
Rattus norvegicus (Norway rat)	Bcl2l2	NP_068622.1
Mus musculus (house mouse)	Bcl2l2	NP_031563.1
Bos taurus (cattle)	BCL2L2	NP_001070001.1
Xenopus tropicalis (tropical clawed frog)	bcl2l2	NP_001011065.1
Homo sapiens (human)	BCL2L2	NP_004041.1
Canis lupus familiaris (dog)	BCL2L2	NP_001026805.1

Gene Ontology
Bibliography

Related articles in PubMed

Long noncoding RNA FTX regulates cardiomyocyte apoptosis by targeting miR-29b-1-5p and Bcl2l2.
Long B, Li N, Xu XX, Li XX, Xu XJ, Guo D, Zhang D, Wu ZH, Zhang SY
Biochemical and biophysical research communications495(1)312-318(2018 01)

Paclitaxel Reduces Axonal Bclw to Initiate IP
Pease-Raissi SE, Pazyra-Murphy MF, Li Y, Wachter F, Fukuda Y, Fenstermacher SJ, Barclay LA, Bird GH, Walensky LD, Segal RA
Neuron96(2)373-386.e6(2017 Oct)

BCL-W has a fundamental role in B cell survival and lymphomagenesis.
Adams CM, Kim AS, Mitra R, Choi JK, Gong JZ, Eischen CM
The Journal of clinical investigation127(2)635-650(2017 Feb)

The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability.
Cosker KE, Fenstermacher SJ, Pazyra-Murphy MF, Elliott HL, Segal RA
Nature neuroscience19(5)690-696(2016 05)

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
Yosef R, Pilpel N, Tokarsky-Amiel R, Biran A, Ovadya Y, Cohen S, Vadai E, Dassa L, Shahar E, Condiotti R, Ben-Porath I, Krizhanovsky V
Nature communications711190(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Bcl2l2
Title: Long noncoding RNA FTX regulates cardiomyocyte apoptosis by targeting miR-29b-1-5p and Bcl2l2.

MYC regulates BCL-W expression through its transcriptional regulation of specific miR.
Title: BCL-W has a fundamental role in B cell survival and lymphomagenesis.

Genetic and pharmacological inhibition of BCL-W and BCL-XL causes directed elimination of senescent cells.
Title: Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.

NF-kappaB p65/p52 signaling mediated the effects of GDNF on Bcl-2 and Bcl-w expressions
Title: NF-?B p65/p52 plays a role in GDNF up-regulating Bcl-2 and Bcl-w expression in 6-OHDA-induced apoptosis of MN9D cell.

Target-derived neurotrophins coordinate transcription of the antiapoptotic gene bclw with transport of bclw mRNA to the axon, and thereby prevent axonal degeneration in rat and mouse sensory neurons.
Title: Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration.

The following Bcl2l2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bcl2l2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu18835	NM_007537.1 Latest version!	Mus musculus BCL2-like 2 (Bcl2l2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu18835	XM_006518457.4 Latest version!	Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu18835	XM_006518458.3 Latest version!	Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu18835	XM_006518458.2	Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu18835	XM_006518457.3	Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bcl2l2 ( NM_007537.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031563.1 Mus musculus BCL2-like 2 (Bcl2l2), mRNA.

Price & Availability↑

CloneID	OMu18835
Clone ID Related Accession (Same CDS sequence)	XM_006518457.3 , XM_006518458.3 , XM_006518458.2 , NM_007537.1 , XM_006518457.4
Accession Version	NM_007537.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	bcl-2-like protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF030769.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF030769.1, AK004680.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031563.1
CDS	179..760
Translation	MATPASTPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQDWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK

Target ORF information:

RefSeq Version	NM_007537.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus BCL2-like 2 (Bcl2l2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007537.1

ORF Insert Sequence:

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bcl2l2 ( XM_006518457.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006518520.1 Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu18835
Clone ID Related Accession (Same CDS sequence)	XM_006518457.3 , XM_006518458.3 , XM_006518458.2 , NM_007537.1 , XM_006518457.4
Accession Version	XM_006518457.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	bcl-2-like protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006518457.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006518520.1
CDS	262..843
Translation	MATPASTPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQDWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK

Target ORF information:

RefSeq Version	XM_006518457.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006518457.3

ORF Insert Sequence:

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bcl2l2 ( XM_006518458.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006518521.1 Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu18835
Clone ID Related Accession (Same CDS sequence)	XM_006518457.3 , XM_006518458.3 , XM_006518458.2 , NM_007537.1 , XM_006518457.4
Accession Version	XM_006518458.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	bcl-2-like protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006518458.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006518521.1
CDS	295..876
Translation	MATPASTPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQDWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK

Target ORF information:

RefSeq Version	XM_006518458.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006518458.2

ORF Insert Sequence:

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bcl2l2 ( XM_006518458.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006518521.1 Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu18835
Clone ID Related Accession (Same CDS sequence)	XM_006518457.3 , XM_006518458.3 , XM_006518458.2 , NM_007537.1 , XM_006518457.4
Accession Version	XM_006518458.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	bcl-2-like protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006518458.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006518521.1
CDS	297..878
Translation	MATPASTPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQDWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK

Target ORF information:

RefSeq Version	XM_006518458.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006518458.3

ORF Insert Sequence:

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bcl2l2 ( XM_006518457.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006518520.1 Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu18835
Clone ID Related Accession (Same CDS sequence)	XM_006518457.3 , XM_006518458.3 , XM_006518458.2 , NM_007537.1 , XM_006518457.4
Accession Version	XM_006518457.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	bcl-2-like protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006518457.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006518520.1
CDS	261..842
Translation	MATPASTPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQDWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK

Target ORF information:

RefSeq Version	XM_006518457.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus BCL2-like 2 (Bcl2l2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006518457.4

ORF Insert Sequence:

ATGGCGACCC CAGCCTCAAC CCCAGACACA CGGGCTCTAG TGGCTGACTT TGTAGGCTAT 
AAGCTGAGGC AGAAGGGTTA TGTCTGTGGA GCTGGCCCTG GGGAAGGCCC AGCCGCCGAC 
CCGCTGCACC AAGCCATGCG GGCTGCTGGA GACGAGTTTG AGACCCGTTT CCGCCGCACC 
TTCTCTGACC TGGCCGCTCA GCTACACGTG ACCCCAGGCT CAGCCCAGCA ACGCTTCACC 
CAGGTTTCCG ACGAACTTTT CCAAGGGGGC CCTAACTGGG GCCGTCTTGT GGCATTCTTT 
GTCTTTGGGG CTGCCCTGTG TGCTGAGAGT GTCAACAAAG AAATGGAGCC TTTGGTGGGA 
CAAGTGCAGG ATTGGATGGT GGCCTACCTG GAGACACGTC TGGCTGACTG GATCCACAGC 
AGTGGGGGCT GGGCGGAGTT CACAGCTCTA TACGGGGACG GGGCCCTGGA GGAGGCACGG 
CGTCTGCGGG AGGGGAACTG GGCATCAGTG AGGACAGTGC TGACGGGGGC CGTGGCACTG 
GGGGCCCTGG TAACTGTAGG GGCCTTTTTT GCTAGCAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Long noncoding RNA FTX regulates cardiomyocyte apoptosis by targeting miR-29b-1-5p and Bcl2l2.
Biochemical and biophysical research communications495(1)312-318(2018 01)
Long B,Li N,Xu XX,Li XX,Xu XJ,Guo D,Zhang D,Wu ZH,Zhang SY

Paclitaxel Reduces Axonal Bclw to Initiate IP
Neuron96(2)373-386.e6(2017 Oct)
Pease-Raissi SE,Pazyra-Murphy MF,Li Y,Wachter F,Fukuda Y,Fenstermacher SJ,Barclay LA,Bird GH,Walensky LD,Segal RA

BCL-W has a fundamental role in B cell survival and lymphomagenesis.
The Journal of clinical investigation127(2)635-650(2017 Feb)
Adams CM,Kim AS,Mitra R,Choi JK,Gong JZ,Eischen CM

The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability.
Nature neuroscience19(5)690-696(2016 05)
Cosker KE,Fenstermacher SJ,Pazyra-Murphy MF,Elliott HL,Segal RA

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
Nature communications711190(2016 Apr)
Yosef R,Pilpel N,Tokarsky-Amiel R,Biran A,Ovadya Y,Cohen S,Vadai E,Dassa L,Shahar E,Condiotti R,Ben-Porath I,Krizhanovsky V

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Bcl2l2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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