Aqp6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Aqp6
Entrez Gene ID	11831
Full Name	aquaporin 6
Synonyms	AI790337
General protein information	Preferred Names aquaporin 6 Names aquaporin-6 AQP-6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 F1\|15 56.13 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006520350.4	XP_006520413.1	aquaporin-6 isoform X1
NM_175087.4	NP_780296.1	aquaporin-6
XM_006520350.3	XP_006520413.1	aquaporin-6 isoform X1
NM_175087.5	NP_780296.1	aquaporin-6

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Aqp6	NP_780296.1
Homo sapiens (human)	AQP6	NP_001643.2
Bos taurus (cattle)	AQP6	XP_002687325.1
Canis lupus familiaris (dog)	AQP6	XP_850452.1
Pan troglodytes (chimpanzee)	AQP6	XP_001157230.1
Rattus norvegicus (Norway rat)	Aqp6	NP_071517.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.
Tanahashi H, Tian QB, Hara Y, Sakagami H, Endo S, Suzuki T
Scientific reports620241(2016 Feb)

Ezh2 represses the basal cell lineage during lung endoderm development.
Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE
Development (Cambridge, England)142(1)108-17(2015 Jan)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney.
Nagalakshmi VK, Ren Q, Pugh MM, Valerius MT, McMahon AP, Yu J
Kidney international79(3)317-30(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that in the inner ear aquaporin-6 is expressed, in both vestibular and acoustic sensory epithelia, by the supporting cells directly contacting hair cells.
Title: Aquaporin-6 expression in the cochlear sensory epithelium is downregulated by salicylates.

AQP6 channel is functionally expressed in parotid acinar cells and contributes to secretion of anions in these cells.
Title: Electrophysiological properties of AQP6 in mouse parotid acinar cells.

Functional analyses of water and ion permeation revealed that mAQP6a functions like rat AQP6 and that mAQP6b does not function as either a water channel or an ion channel under our experimental conditions
Title: Molecular cloning and characterization of mouse aquaporin 6.

The following Aqp6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Aqp6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04833	NM_175087.5 Latest version!	Mus musculus aquaporin 6 (Aqp6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu50885	XM_006520350.4 Latest version!	Mus musculus aquaporin 6 (Aqp6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu50885	XM_006520350.3	Mus musculus aquaporin 6 (Aqp6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu04833	NM_175087.4	Mus musculus aquaporin 6 (Aqp6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Aqp6 ( NM_175087.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780296.1 Mus musculus aquaporin 6 (Aqp6), mRNA.

Price & Availability↑

CloneID	OMu04833
Clone ID Related Accession (Same CDS sequence)	NM_175087.4 , NM_175087.5
Accession Version	NM_175087.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-31
Organism	Mus musculus(house mouse)
Product	aquaporin-6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC139317.4. On May 2, 2007 this sequence version replaced NM_175087.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK082699.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849385, SAMN01164136 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCCAG GGCTGTGTAG CAGGGCTTAC CTTCTGGTTG GCGGGCTTTG GACCGCCATC 
AGCAAGGCGC TTTTTGCTGA GTTCCTGGCC ACGGGGCTGT ACGTTTTCTT TGGTGTGGGC 
TCTGTTCTGC CCTGGCCTGT GGCGCTTCCC TCTGTGCTCC AGATCGCCAT CACCTTCAAT 
CTGGCCACAG CCACAGCCGT GCAGATCTCC TGGAAGACCA GCGGGGCCCA CGCCAACCCT 
GCTGTGACCC TGGCCTACCT CGTGGGATCC CATATCTCTC TGCCTCGGGC TATGGCCTAT 
ATCGCTGCGC AGCTGGCTGG GGCCACAGCT GGGGCTGCTC TTCTTTACGG GGTAACTCCA 
GGAGGTATTC GAGAGACCCT TGGGGTCAAC GTGGTCCACA ACAGCACATC AACTGGCCAG 
GCGGTGGCCG TGGAGCTGGT TCTGACGCTG CAGCTGGTGC TCTGTGTCTT TGCTTCCATG 
GATGGCCGGC AGACCTTGGC GTCCCCAGCT GCCATGATTG GAACCTCTGT GGCACTGGGC 
CACCTCATTG GGATCTACTT CACTGGCTGT TCCATGAACC CAGCCCGCTC CTTCGGCCCT 
GCCGTCATTG TTGGGAAGTT CGCAGTCCAT TGGATCTTCT GGGTAGGACC GCTCACAGGG 
GCTGTCCTGG CTTCGCTGAT CTACAACTTT ATCTTGTTCC CTGACACCAA GACTGTAGCC 
CAGCGATTGG CCATCCTTGT GGGCACCACA AAGGTGGAGA AAGTGGTAGA CCTGGAGCCC 
CAGAAGAAAG AATCACAGAC AAACTCTGAG GACACAGAAT GTTTGACTTC TCCGTGTGAG 
GAGGCTGTCC GGTCATTTTC ATTCACGCTT GGCCTTTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780296.1
CDS	9..890
Translation	MEPGLCSRAYLLVGGLWTAISKALFAEFLATGLYVFFGVGSVLPWPVALPSVLQIAITFNLATATAVQISWKTSGAHANPAVTLAYLVGSHISLPRAMAYIAAQLAGATAGAALLYGVTPGGIRETLGVNVVHNSTSTGQAVAVELVLTLQLVLCVFASMDGRQTLASPAAMIGTSVALGHLIGIYFTGCSMNPARSFGPAVIVGKFAVHWIFWVGPLTGAVLASLIYNFILFPDTKTVAQRLAILVGTTKVEKVVDLEPQKKESQTNSEDTECLTSPCEEAVRSFSFTLGLC

Target ORF information:

RefSeq Version	NM_175087.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus aquaporin 6 (Aqp6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175087.4

ORF Insert Sequence:

ATGGAGCCAG GGCTGTGTAG CAGGGCTTAC CTTCTGGTTG GCGGGCTTTG GACCGCCATC 
AGCAAGGCGC TTTTTGCTGA GTTCCTGGCC ACGGGGCTGT ACGTTTTCTT TGGTGTGGGC 
TCTGTTCTGC CCTGGCCTGT GGCGCTTCCC TCTGTGCTCC AGATCGCCAT CACCTTCAAT 
CTGGCCACAG CCACAGCCGT GCAGATCTCC TGGAAGACCA GCGGGGCCCA CGCCAACCCT 
GCTGTGACCC TGGCCTACCT CGTGGGATCC CATATCTCTC TGCCTCGGGC TATGGCCTAT 
ATCGCTGCGC AGCTGGCTGG GGCCACAGCT GGGGCTGCTC TTCTTTACGG GGTAACTCCA 
GGAGGTATTC GAGAGACCCT TGGGGTCAAC GTGGTCCACA ACAGCACATC AACTGGCCAG 
GCGGTGGCCG TGGAGCTGGT TCTGACGCTG CAGCTGGTGC TCTGTGTCTT TGCTTCCATG 
GATGGCCGGC AGACCTTGGC GTCCCCAGCT GCCATGATTG GAACCTCTGT GGCACTGGGC 
CACCTCATTG GGATCTACTT CACTGGCTGT TCCATGAACC CAGCCCGCTC CTTCGGCCCT 
GCCGTCATTG TTGGGAAGTT CGCAGTCCAT TGGATCTTCT GGGTAGGACC GCTCACAGGG 
GCTGTCCTGG CTTCGCTGAT CTACAACTTT ATCTTGTTCC CTGACACCAA GACTGTAGCC 
CAGCGATTGG CCATCCTTGT GGGCACCACA AAGGTGGAGA AAGTGGTAGA CCTGGAGCCC 
CAGAAGAAAG AATCACAGAC AAACTCTGAG GACACAGAAT GTTTGACTTC TCCGTGTGAG 
GAGGCTGTCC GGTCATTTTC ATTCACGCTT GGCCTTTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aqp6 ( NM_175087.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780296.1 Mus musculus aquaporin 6 (Aqp6), mRNA.

Price & Availability↑

CloneID	OMu04833
Clone ID Related Accession (Same CDS sequence)	NM_175087.4 , NM_175087.5
Accession Version	NM_175087.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	aquaporin-6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC139317.4 and AK082699.1. On Mar 28, 2018 this sequence version replaced NM_175087.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK082699.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849385, SAMN01164136 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCAG GGCTGTGTAG CAGGGCTTAC CTTCTGGTTG GCGGGCTTTG GACCGCCATC 
AGCAAGGCGC TTTTTGCTGA GTTCCTGGCC ACGGGGCTGT ACGTTTTCTT TGGTGTGGGC 
TCTGTTCTGC CCTGGCCTGT GGCGCTTCCC TCTGTGCTCC AGATCGCCAT CACCTTCAAT 
CTGGCCACAG CCACAGCCGT GCAGATCTCC TGGAAGACCA GCGGGGCCCA CGCCAACCCT 
GCTGTGACCC TGGCCTACCT CGTGGGATCC CATATCTCTC TGCCTCGGGC TATGGCCTAT 
ATCGCTGCGC AGCTGGCTGG GGCCACAGCT GGGGCTGCTC TTCTTTACGG GGTAACTCCA 
GGAGGTATTC GAGAGACCCT TGGGGTCAAC GTGGTCCACA ACAGCACATC AACTGGCCAG 
GCGGTGGCCG TGGAGCTGGT TCTGACGCTG CAGCTGGTGC TCTGTGTCTT TGCTTCCATG 
GATGGCCGGC AGACCTTGGC GTCCCCAGCT GCCATGATTG GAACCTCTGT GGCACTGGGC 
CACCTCATTG GGATCTACTT CACTGGCTGT TCCATGAACC CAGCCCGCTC CTTCGGCCCT 
GCCGTCATTG TTGGGAAGTT CGCAGTCCAT TGGATCTTCT GGGTAGGACC GCTCACAGGG 
GCTGTCCTGG CTTCGCTGAT CTACAACTTT ATCTTGTTCC CTGACACCAA GACTGTAGCC 
CAGCGATTGG CCATCCTTGT GGGCACCACA AAGGTGGAGA AAGTGGTAGA CCTGGAGCCC 
CAGAAGAAAG AATCACAGAC AAACTCTGAG GACACAGAAT GTTTGACTTC TCCGTGTGAG 
GAGGCTGTCC GGTCATTTTC ATTCACGCTT GGCCTTTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780296.1
CDS	209..1090
Translation	MEPGLCSRAYLLVGGLWTAISKALFAEFLATGLYVFFGVGSVLPWPVALPSVLQIAITFNLATATAVQISWKTSGAHANPAVTLAYLVGSHISLPRAMAYIAAQLAGATAGAALLYGVTPGGIRETLGVNVVHNSTSTGQAVAVELVLTLQLVLCVFASMDGRQTLASPAAMIGTSVALGHLIGIYFTGCSMNPARSFGPAVIVGKFAVHWIFWVGPLTGAVLASLIYNFILFPDTKTVAQRLAILVGTTKVEKVVDLEPQKKESQTNSEDTECLTSPCEEAVRSFSFTLGLC

Target ORF information:

RefSeq Version	NM_175087.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus aquaporin 6 (Aqp6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175087.5

ORF Insert Sequence:

ATGGAGCCAG GGCTGTGTAG CAGGGCTTAC CTTCTGGTTG GCGGGCTTTG GACCGCCATC 
AGCAAGGCGC TTTTTGCTGA GTTCCTGGCC ACGGGGCTGT ACGTTTTCTT TGGTGTGGGC 
TCTGTTCTGC CCTGGCCTGT GGCGCTTCCC TCTGTGCTCC AGATCGCCAT CACCTTCAAT 
CTGGCCACAG CCACAGCCGT GCAGATCTCC TGGAAGACCA GCGGGGCCCA CGCCAACCCT 
GCTGTGACCC TGGCCTACCT CGTGGGATCC CATATCTCTC TGCCTCGGGC TATGGCCTAT 
ATCGCTGCGC AGCTGGCTGG GGCCACAGCT GGGGCTGCTC TTCTTTACGG GGTAACTCCA 
GGAGGTATTC GAGAGACCCT TGGGGTCAAC GTGGTCCACA ACAGCACATC AACTGGCCAG 
GCGGTGGCCG TGGAGCTGGT TCTGACGCTG CAGCTGGTGC TCTGTGTCTT TGCTTCCATG 
GATGGCCGGC AGACCTTGGC GTCCCCAGCT GCCATGATTG GAACCTCTGT GGCACTGGGC 
CACCTCATTG GGATCTACTT CACTGGCTGT TCCATGAACC CAGCCCGCTC CTTCGGCCCT 
GCCGTCATTG TTGGGAAGTT CGCAGTCCAT TGGATCTTCT GGGTAGGACC GCTCACAGGG 
GCTGTCCTGG CTTCGCTGAT CTACAACTTT ATCTTGTTCC CTGACACCAA GACTGTAGCC 
CAGCGATTGG CCATCCTTGT GGGCACCACA AAGGTGGAGA AAGTGGTAGA CCTGGAGCCC 
CAGAAGAAAG AATCACAGAC AAACTCTGAG GACACAGAAT GTTTGACTTC TCCGTGTGAG 
GAGGCTGTCC GGTCATTTTC ATTCACGCTT GGCCTTTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aqp6 ( XM_006520350.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520413.1 Mus musculus aquaporin 6 (Aqp6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu50885
Clone ID Related Accession (Same CDS sequence)	XM_006520350.4 , XM_006520350.3
Accession Version	XM_006520350.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	aquaporin-6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520350.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCAG GGCTGTGTAG CAGGGCTTAC CTTCTGGTTG GCGGGCTTTG GACCGCCATC 
AGCAAGGCGC TTTTTGCTGA GTTCCTGGCC ACGGGGCTGT ACGTTTTCTT TGGTGTGGGC 
TCTGTTCTGC CCTGGCCTGT GGCGCTTCCC TCTGTGCTCC AGATCGCCAT CACCTTCAAT 
CTGGCCACAG CCACAGCCGT GCAGATCTCC TGGAAGACCA GCGGGGCCCA CGCCAACCCT 
GCTGTGACCC TGGCCTACCT CGTGGGATCC CATATCTCTC TGCCTCGGGC TATGGCCTAT 
ATCGCTGCGC AGCTGGCTGG GGCCACAGCT GGGGCTGCTC TTCTTTACGG GGTAACTCCA 
GGAGGTATTC GAGAGACCCT TGGGGTCAAC GTGGTCCACA ACAGCACATC AACTGGCCAG 
GCGGTGGCCG TGGAGCTGGT TCTGACGCTG CAGCTGGTGC TCTGTGTCTT TGCTTCCATG 
GATGGCCGGC AGACCTTGGC GTCCCCAGCT GCCATGATTG GAACCTCTGT GGCACTGGGC 
CACCTCATTG GGATCTACTT CACTGGCTGT TCCATGAACC CAGCCCGCTC CTTCGGCCCT 
GCCGTCATTG TTGGGAAGTT CGCAGTCCAT TGGTGTTTGA CTTCTCCGTG TGAGGAGGCT 
GTCCGGTCAT TTTCATTCAC GCTTGGCCTT TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520413.1
CDS	720..1415
Translation	MEPGLCSRAYLLVGGLWTAISKALFAEFLATGLYVFFGVGSVLPWPVALPSVLQIAITFNLATATAVQISWKTSGAHANPAVTLAYLVGSHISLPRAMAYIAAQLAGATAGAALLYGVTPGGIRETLGVNVVHNSTSTGQAVAVELVLTLQLVLCVFASMDGRQTLASPAAMIGTSVALGHLIGIYFTGCSMNPARSFGPAVIVGKFAVHWCLTSPCEEAVRSFSFTLGLC

Target ORF information:

RefSeq Version	XM_006520350.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus aquaporin 6 (Aqp6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520350.3

ORF Insert Sequence:

ATGGAGCCAG GGCTGTGTAG CAGGGCTTAC CTTCTGGTTG GCGGGCTTTG GACCGCCATC 
AGCAAGGCGC TTTTTGCTGA GTTCCTGGCC ACGGGGCTGT ACGTTTTCTT TGGTGTGGGC 
TCTGTTCTGC CCTGGCCTGT GGCGCTTCCC TCTGTGCTCC AGATCGCCAT CACCTTCAAT 
CTGGCCACAG CCACAGCCGT GCAGATCTCC TGGAAGACCA GCGGGGCCCA CGCCAACCCT 
GCTGTGACCC TGGCCTACCT CGTGGGATCC CATATCTCTC TGCCTCGGGC TATGGCCTAT 
ATCGCTGCGC AGCTGGCTGG GGCCACAGCT GGGGCTGCTC TTCTTTACGG GGTAACTCCA 
GGAGGTATTC GAGAGACCCT TGGGGTCAAC GTGGTCCACA ACAGCACATC AACTGGCCAG 
GCGGTGGCCG TGGAGCTGGT TCTGACGCTG CAGCTGGTGC TCTGTGTCTT TGCTTCCATG 
GATGGCCGGC AGACCTTGGC GTCCCCAGCT GCCATGATTG GAACCTCTGT GGCACTGGGC 
CACCTCATTG GGATCTACTT CACTGGCTGT TCCATGAACC CAGCCCGCTC CTTCGGCCCT 
GCCGTCATTG TTGGGAAGTT CGCAGTCCAT TGGTGTTTGA CTTCTCCGTG TGAGGAGGCT 
GTCCGGTCAT TTTCATTCAC GCTTGGCCTT TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aqp6 ( XM_006520350.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520413.1 Mus musculus aquaporin 6 (Aqp6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu50885
Clone ID Related Accession (Same CDS sequence)	XM_006520350.4 , XM_006520350.3
Accession Version	XM_006520350.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	aquaporin-6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006520350.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCAG GGCTGTGTAG CAGGGCTTAC CTTCTGGTTG GCGGGCTTTG GACCGCCATC 
AGCAAGGCGC TTTTTGCTGA GTTCCTGGCC ACGGGGCTGT ACGTTTTCTT TGGTGTGGGC 
TCTGTTCTGC CCTGGCCTGT GGCGCTTCCC TCTGTGCTCC AGATCGCCAT CACCTTCAAT 
CTGGCCACAG CCACAGCCGT GCAGATCTCC TGGAAGACCA GCGGGGCCCA CGCCAACCCT 
GCTGTGACCC TGGCCTACCT CGTGGGATCC CATATCTCTC TGCCTCGGGC TATGGCCTAT 
ATCGCTGCGC AGCTGGCTGG GGCCACAGCT GGGGCTGCTC TTCTTTACGG GGTAACTCCA 
GGAGGTATTC GAGAGACCCT TGGGGTCAAC GTGGTCCACA ACAGCACATC AACTGGCCAG 
GCGGTGGCCG TGGAGCTGGT TCTGACGCTG CAGCTGGTGC TCTGTGTCTT TGCTTCCATG 
GATGGCCGGC AGACCTTGGC GTCCCCAGCT GCCATGATTG GAACCTCTGT GGCACTGGGC 
CACCTCATTG GGATCTACTT CACTGGCTGT TCCATGAACC CAGCCCGCTC CTTCGGCCCT 
GCCGTCATTG TTGGGAAGTT CGCAGTCCAT TGGTGTTTGA CTTCTCCGTG TGAGGAGGCT 
GTCCGGTCAT TTTCATTCAC GCTTGGCCTT TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520413.1
CDS	2941..3636
Translation	MEPGLCSRAYLLVGGLWTAISKALFAEFLATGLYVFFGVGSVLPWPVALPSVLQIAITFNLATATAVQISWKTSGAHANPAVTLAYLVGSHISLPRAMAYIAAQLAGATAGAALLYGVTPGGIRETLGVNVVHNSTSTGQAVAVELVLTLQLVLCVFASMDGRQTLASPAAMIGTSVALGHLIGIYFTGCSMNPARSFGPAVIVGKFAVHWCLTSPCEEAVRSFSFTLGLC

Target ORF information:

RefSeq Version	XM_006520350.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus aquaporin 6 (Aqp6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520350.4

ORF Insert Sequence:

ATGGAGCCAG GGCTGTGTAG CAGGGCTTAC CTTCTGGTTG GCGGGCTTTG GACCGCCATC 
AGCAAGGCGC TTTTTGCTGA GTTCCTGGCC ACGGGGCTGT ACGTTTTCTT TGGTGTGGGC 
TCTGTTCTGC CCTGGCCTGT GGCGCTTCCC TCTGTGCTCC AGATCGCCAT CACCTTCAAT 
CTGGCCACAG CCACAGCCGT GCAGATCTCC TGGAAGACCA GCGGGGCCCA CGCCAACCCT 
GCTGTGACCC TGGCCTACCT CGTGGGATCC CATATCTCTC TGCCTCGGGC TATGGCCTAT 
ATCGCTGCGC AGCTGGCTGG GGCCACAGCT GGGGCTGCTC TTCTTTACGG GGTAACTCCA 
GGAGGTATTC GAGAGACCCT TGGGGTCAAC GTGGTCCACA ACAGCACATC AACTGGCCAG 
GCGGTGGCCG TGGAGCTGGT TCTGACGCTG CAGCTGGTGC TCTGTGTCTT TGCTTCCATG 
GATGGCCGGC AGACCTTGGC GTCCCCAGCT GCCATGATTG GAACCTCTGT GGCACTGGGC 
CACCTCATTG GGATCTACTT CACTGGCTGT TCCATGAACC CAGCCCGCTC CTTCGGCCCT 
GCCGTCATTG TTGGGAAGTT CGCAGTCCAT TGGTGTTTGA CTTCTCCGTG TGAGGAGGCT 
GTCCGGTCAT TTTCATTCAC GCTTGGCCTT TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.
Scientific reports620241(2016 Feb)
Tanahashi H,Tian QB,Hara Y,Sakagami H,Endo S,Suzuki T

Ezh2 represses the basal cell lineage during lung endoderm development.
Development (Cambridge, England)142(1)108-17(2015 Jan)
Snitow ME,Li S,Morley MP,Rathi K,Lu MM,Kadzik RS,Stewart KM,Morrisey EE

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney.
Kidney international79(3)317-30(2011 Feb)
Nagalakshmi VK,Ren Q,Pugh MM,Valerius MT,McMahon AP,Yu J

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Aqp6 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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