Birc5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Birc5
Entrez Gene ID	11799
Full Name	baculoviral IAP repeat-containing 5
Synonyms	AAC-11,Api4,TIAP,survivin40
General protein information	Preferred Names baculoviral IAP repeat-containing 5 Names baculoviral IAP repeat-containing protein 5 apoptosis inhibitor 4 apoptosis inhibitor survivin survivin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 E2
Summary	This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. In humans, gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts have been identified in human that regulate this gene's expression. At least three transcript variants encoding distinct isoforms have been found for this gene, although at least one of these transcript variants is a nonsense-mediated decay (NMD) candidate. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012273.1	NP_001012273.1	baculoviral IAP repeat-containing protein 5 isoform 3
NM_009689.2	NP_033819.1	baculoviral IAP repeat-containing protein 5 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	BIRC5	NP_001159.2
Gallus gallus (chicken)	BIRC5	NP_001012318.1
Pan troglodytes (chimpanzee)	BIRC5	NP_001233436.1
Mus musculus (house mouse)	Birc5	NP_033819.1
Danio rerio (zebrafish)	birc5a	NP_919378.1
	BIRC5	XP_001108164.1
Canis lupus familiaris (dog)	BIRC5	NP_001003348.1
Xenopus tropicalis (tropical clawed frog)	birc5.2	NP_001037948.1
Bos taurus (cattle)	BIRC5	NP_001001855.2
Rattus norvegicus (Norway rat)	Birc5	NP_071610.1

Gene Ontology

The following Birc5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Birc5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18820	NM_001012273.1 Latest version!	Mus musculus baculoviral IAP repeat-containing 5 (Birc5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu18865	NM_009689.2 Latest version!	Mus musculus baculoviral IAP repeat-containing 5 (Birc5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Birc5 ( NM_001012273.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001012273.1 Mus musculus baculoviral IAP repeat-containing 5 (Birc5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu18820
Clone ID Related Accession (Same CDS sequence)	NM_001012273.1
Accession Version	NM_001012273.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-28
Organism	Mus musculus(house mouse)
Product	baculoviral IAP repeat-containing protein 5 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY023910.1, AB013819.1 and BC004702.1. Transcript Variant: This variant (3), also known as survivin121, uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform 3 which has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004702.1, CD349576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGCTC CGGCGCTGCC CCAGATCTGG CAGCTGTACC TCAAGAACTA CCGCATCGCC 
ACCTTCAAGA ACTGGCCCTT CCTGGAGGAC TGCGCCTGCA CCCCAGAGCG AATGGCGGAG 
GCTGGCTTCA TCCACTGCCC TACCGAGAAC GAGCCTGATT TGGCCCAGTG TTTTTTCTGC 
TTTAAGGAAT TGGAAGGCTG GGAACCCGAT GACAACCCGA TAGAGGAGCA TAGAAAGCAC 
TCCCCTGGCT GCGCCTTCCT CACTGTCAAG AAGCAGATGG AAGAACTAAC CGTCAGTGAA 
TTCTTGAAAC TGGACAGACA GAGAGCCAAG AACAAAATTG TATGTATGAT TGAGAATAAG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012273.1
CDS	115..480
Translation	MGAPALPQIWQLYLKNYRIATFKNWPFLEDCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEEHRKHSPGCAFLTVKKQMEELTVSEFLKLDRQRAKNKIVCMIENKD

Target ORF information:

RefSeq Version	NM_001012273.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus baculoviral IAP repeat-containing 5 (Birc5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012273.1

ORF Insert Sequence:

ATGGGAGCTC CGGCGCTGCC CCAGATCTGG CAGCTGTACC TCAAGAACTA CCGCATCGCC 
ACCTTCAAGA ACTGGCCCTT CCTGGAGGAC TGCGCCTGCA CCCCAGAGCG AATGGCGGAG 
GCTGGCTTCA TCCACTGCCC TACCGAGAAC GAGCCTGATT TGGCCCAGTG TTTTTTCTGC 
TTTAAGGAAT TGGAAGGCTG GGAACCCGAT GACAACCCGA TAGAGGAGCA TAGAAAGCAC 
TCCCCTGGCT GCGCCTTCCT CACTGTCAAG AAGCAGATGG AAGAACTAAC CGTCAGTGAA 
TTCTTGAAAC TGGACAGACA GAGAGCCAAG AACAAAATTG TATGTATGAT TGAGAATAAG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Birc5 ( NM_009689.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033819.1 Mus musculus baculoviral IAP repeat-containing 5 (Birc5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu18865
Clone ID Related Accession (Same CDS sequence)	NM_009689.2
Accession Version	NM_009689.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	baculoviral IAP repeat-containing protein 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN724527.1, AB013819.1 and AI413910.1. On Feb 16, 2005 this sequence version replaced NM_009689.1. Transcript Variant: This variant (1), also known as survivin140, represents the most frequently occurring transcript and it encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CN724527.1, AB013819.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGCTC CGGCGCTGCC CCAGATCTGG CAGCTGTACC TCAAGAACTA CCGCATCGCC 
ACCTTCAAGA ACTGGCCCTT CCTGGAGGAC TGCGCCTGCA CCCCAGAGCG AATGGCGGAG 
GCTGGCTTCA TCCACTGCCC TACCGAGAAC GAGCCTGATT TGGCCCAGTG TTTTTTCTGC 
TTTAAGGAAT TGGAAGGCTG GGAACCCGAT GACAACCCGA TAGAGGAGCA TAGAAAGCAC 
TCCCCTGGCT GCGCCTTCCT CACTGTCAAG AAGCAGATGG AAGAACTAAC CGTCAGTGAA 
TTCTTGAAAC TGGACAGACA GAGAGCCAAG AACAAAATTG CAAAGGAGAC CAACAACAAG 
CAAAAAGAGT TTGAAGAGAC TGCAAAGACT ACCCGTCAGT CAATTGAGCA GCTGGCTGCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033819.1
CDS	115..537
Translation	MGAPALPQIWQLYLKNYRIATFKNWPFLEDCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEEHRKHSPGCAFLTVKKQMEELTVSEFLKLDRQRAKNKIAKETNNKQKEFEETAKTTRQSIEQLAA

Target ORF information:

RefSeq Version	NM_009689.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus baculoviral IAP repeat-containing 5 (Birc5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009689.2

ORF Insert Sequence:

ATGGGAGCTC CGGCGCTGCC CCAGATCTGG CAGCTGTACC TCAAGAACTA CCGCATCGCC 
ACCTTCAAGA ACTGGCCCTT CCTGGAGGAC TGCGCCTGCA CCCCAGAGCG AATGGCGGAG 
GCTGGCTTCA TCCACTGCCC TACCGAGAAC GAGCCTGATT TGGCCCAGTG TTTTTTCTGC 
TTTAAGGAAT TGGAAGGCTG GGAACCCGAT GACAACCCGA TAGAGGAGCA TAGAAAGCAC 
TCCCCTGGCT GCGCCTTCCT CACTGTCAAG AAGCAGATGG AAGAACTAAC CGTCAGTGAA 
TTCTTGAAAC TGGACAGACA GAGAGCCAAG AACAAAATTG CAAAGGAGAC CAACAACAAG 
CAAAAAGAGT TTGAAGAGAC TGCAAAGACT ACCCGTCAGT CAATTGAGCA GCTGGCTGCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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Birc5 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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