Ap1s1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ap1s1
Entrez Gene ID	11769
Full Name	adaptor protein complex AP-1, sigma 1
Synonyms	AP19
General protein information	Preferred Names adaptor protein complex AP-1, sigma 1 Names AP-1 complex subunit sigma-1A HA1 19 kDa subunit adapter-related protein complex 1 sigma-1A subunit adapter-related protein complex 1 subunit sigma-1A adaptor protein complex AP-1 sigma-1A subunit adaptor protein complex AP-1 subunit sigma-1A adaptor-related protein complex 1 subunit sigma-1A adaptor-related protein complex AP-1, sigma 1 clathrin assembly protein complex 1 sigma-1A small chain clathrin coat assembly protein AP19 golgi adaptor HA1/AP1 adaptin sigma-1A subunit sigma 1a subunit of AP-1 clathrin sigma-adaptin 1A sigma1A-adaptin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 G2

mRNA and Protein(s)

mRNA	Protein	Name
NM_007457.2	NP_031483.1	AP-1 complex subunit sigma-1A
NM_007457.3	NP_031483.1	AP-1 complex subunit sigma-1A
XM_006504348.3	XP_006504411.1	AP-1 complex subunit sigma-1A isoform X1
XM_006504348.4	XP_006504411.1	AP-1 complex subunit sigma-1A isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	AP1S1	NP_001274.1
Mus musculus (house mouse)	Ap1s1	NP_031483.1
Rattus norvegicus (Norway rat)	Ap1s1	NP_001101801.2
Xenopus tropicalis (tropical clawed frog)	ap1s1	NP_989338.1
Danio rerio (zebrafish)	zgc:162858	NP_001082809.1
Pan troglodytes (chimpanzee)	AP1S1	XP_001153078.2
Bos taurus (cattle)	AP1S1	NP_001070578.1
Canis lupus familiaris (dog)	AP1S1	XP_003434784.1

Gene Ontology
Bibliography

Related articles in PubMed

AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway.
Candiello E, Kratzke M, Wenzel D, Cassel D, Schu P
Scientific reports629950(2016 Jul)

?1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue.
Baltes J, Larsen JV, Radhakrishnan K, Geumann C, Kratzke M, Petersen CM, Schu P
Journal of cell science127(Pt 16)3477-87(2014 Aug)

Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: ?1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.
Moreno E, Moreno-Delgado D, Navarro G, Hoffmann HM, Fuentes S, Rosell-Vilar S, Gasperini P, Rodr?guez-Ruiz M, Medrano M, Mallol J, Cort?s A, Casad? V, Llu?s C, Ferr? S, Ortiz J, Canela E, McCormick PJ
The Journal of neuroscience : the official journal of the Society for Neuroscience34(10)3545-58(2014 Mar)

AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory.
Glyvuk N, Tsytsyura Y, Geumann C, D'Hooge R, H?ve J, Kratzke M, Baltes J, Boening D, B?ning D, Klingauf J, Schu P
The EMBO journal29(8)1318-30(2010 Apr)

The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.
Doray B, Lee I, Knisely J, Bu G, Kornfeld S
Molecular biology of the cell18(5)1887-96(2007 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ap1s1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ap1s1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu00206	NM_007457.3 Latest version!	Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu36103	XM_006504348.4 Latest version!	Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu00206	NM_007457.2	Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu36103	XM_006504348.3	Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ap1s1 ( XM_006504348.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504411.1 Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu36103
Clone ID Related Accession (Same CDS sequence)	XM_006504348.3 , XM_006504348.4
Accession Version	XM_006504348.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	AP-1 complex subunit sigma-1A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504348.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCAGA AGAAAGGTCA GGCCTTAGAG TGCACACCTG TAACCTGGTA CTCAGAGATG 
CGATTCATGC TACTGTTCAG CCGGCAGGGA AAACTTCGGC TACAAAAATG GTACCTGGCC 
ACCTCAGACA AGGAGAGGAA GAAGATGGTC CGAGAGCTCA TGCAAGTCGT CCTGGCTAGA 
AAGCCCAAAA TGTGCAGCTT CCTGGAGTGG AGGGACCTCA AAGTTGTCTA TAAGAGATAC 
GCCAGTCTCT ATTTCTGCTG CGCCATCGAA GGCCAAGACA ACGAGCTGAT CACACTGGAG 
CTGATCCACC GATACGTAGA GCTCTTGGAC AAGTACTTCG GCAGCGTATG TGAGTTGGAC 
ATCATCTTCA ACTTTGAGAA AGCCTACTTT ATCCTGGACG AGTTTCTGAT GGGTGGGGAT 
GTCCAGGACA CCTCCAAGAA GAGTGTGCTC AAGGCCATTG AGCAGGCTGA CCTGCTGCAG 
GAGGAGGATG AGTCGCCGCG CAGTGTCCTG GAGGAGATGG GCCTGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504411.1
CDS	941..1471
Translation	MSQKKGQALECTPVTWYSEMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA

Target ORF information:

RefSeq Version	XM_006504348.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504348.3

ORF Insert Sequence:

ATGTCTCAGA AGAAAGGTCA GGCCTTAGAG TGCACACCTG TAACCTGGTA CTCAGAGATG 
CGATTCATGC TACTGTTCAG CCGGCAGGGA AAACTTCGGC TACAAAAATG GTACCTGGCC 
ACCTCAGACA AGGAGAGGAA GAAGATGGTC CGAGAGCTCA TGCAAGTCGT CCTGGCTAGA 
AAGCCCAAAA TGTGCAGCTT CCTGGAGTGG AGGGACCTCA AAGTTGTCTA TAAGAGATAC 
GCCAGTCTCT ATTTCTGCTG CGCCATCGAA GGCCAAGACA ACGAGCTGAT CACACTGGAG 
CTGATCCACC GATACGTAGA GCTCTTGGAC AAGTACTTCG GCAGCGTATG TGAGTTGGAC 
ATCATCTTCA ACTTTGAGAA AGCCTACTTT ATCCTGGACG AGTTTCTGAT GGGTGGGGAT 
GTCCAGGACA CCTCCAAGAA GAGTGTGCTC AAGGCCATTG AGCAGGCTGA CCTGCTGCAG 
GAGGAGGATG AGTCGCCGCG CAGTGTCCTG GAGGAGATGG GCCTGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap1s1 ( NM_007457.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031483.1 Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), mRNA.

Price & Availability↑

CloneID	OMu00206
Clone ID Related Accession (Same CDS sequence)	NM_007457.2 , NM_007457.3
Accession Version	NM_007457.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Mus musculus(house mouse)
Product	AP-1 complex subunit sigma-1A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC147986.3. On Nov 17, 2006 this sequence version replaced NM_007457.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M62418.1, BC052692.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGATGCGAT TCATGCTACT GTTCAGCCGG CAGGGAAAAC TTCGGCTACA AAAATGGTAC 
CTGGCCACCT CAGACAAGGA GAGGAAGAAG ATGGTCCGAG AGCTCATGCA AGTCGTCCTG 
GCTAGAAAGC CCAAAATGTG CAGCTTCCTG GAGTGGAGGG ACCTCAAAGT TGTCTATAAG 
AGATACGCCA GTCTCTATTT CTGCTGCGCC ATCGAAGGCC AAGACAACGA GCTGATCACA 
CTGGAGCTGA TCCACCGATA CGTAGAGCTC TTGGACAAGT ACTTCGGCAG CGTATGTGAG 
TTGGACATCA TCTTCAACTT TGAGAAAGCC TACTTTATCC TGGACGAGTT TCTGATGGGT 
GGGGATGTCC AGGACACCTC CAAGAAGAGT GTGCTCAAGG CCATTGAGCA GGCTGACCTG 
CTGCAGGAGG AGGATGAGTC GCCGCGCAGT GTCCTGGAGG AGATGGGCCT GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031483.1
CDS	51..527
Translation	MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA

Target ORF information:

RefSeq Version	NM_007457.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007457.2

ORF Insert Sequence:

ATGATGCGAT TCATGCTACT GTTCAGCCGG CAGGGAAAAC TTCGGCTACA AAAATGGTAC 
CTGGCCACCT CAGACAAGGA GAGGAAGAAG ATGGTCCGAG AGCTCATGCA AGTCGTCCTG 
GCTAGAAAGC CCAAAATGTG CAGCTTCCTG GAGTGGAGGG ACCTCAAAGT TGTCTATAAG 
AGATACGCCA GTCTCTATTT CTGCTGCGCC ATCGAAGGCC AAGACAACGA GCTGATCACA 
CTGGAGCTGA TCCACCGATA CGTAGAGCTC TTGGACAAGT ACTTCGGCAG CGTATGTGAG 
TTGGACATCA TCTTCAACTT TGAGAAAGCC TACTTTATCC TGGACGAGTT TCTGATGGGT 
GGGGATGTCC AGGACACCTC CAAGAAGAGT GTGCTCAAGG CCATTGAGCA GGCTGACCTG 
CTGCAGGAGG AGGATGAGTC GCCGCGCAGT GTCCTGGAGG AGATGGGCCT GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap1s1 ( NM_007457.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031483.1 Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), mRNA.

Price & Availability↑

CloneID	OMu00206
Clone ID Related Accession (Same CDS sequence)	NM_007457.2 , NM_007457.3
Accession Version	NM_007457.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	AP-1 complex subunit sigma-1A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY253222.1 and BC052692.1. On Mar 28, 2018 this sequence version replaced NM_007457.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052692.1, M62418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGCGAT TCATGCTACT GTTCAGCCGG CAGGGAAAAC TTCGGCTACA AAAATGGTAC 
CTGGCCACCT CAGACAAGGA GAGGAAGAAG ATGGTCCGAG AGCTCATGCA AGTCGTCCTG 
GCTAGAAAGC CCAAAATGTG CAGCTTCCTG GAGTGGAGGG ACCTCAAAGT TGTCTATAAG 
AGATACGCCA GTCTCTATTT CTGCTGCGCC ATCGAAGGCC AAGACAACGA GCTGATCACA 
CTGGAGCTGA TCCACCGATA CGTAGAGCTC TTGGACAAGT ACTTCGGCAG CGTATGTGAG 
TTGGACATCA TCTTCAACTT TGAGAAAGCC TACTTTATCC TGGACGAGTT TCTGATGGGT 
GGGGATGTCC AGGACACCTC CAAGAAGAGT GTGCTCAAGG CCATTGAGCA GGCTGACCTG 
CTGCAGGAGG AGGATGAGTC GCCGCGCAGT GTCCTGGAGG AGATGGGCCT GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031483.1
CDS	99..575
Translation	MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA

Target ORF information:

RefSeq Version	NM_007457.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007457.3

ORF Insert Sequence:

ATGATGCGAT TCATGCTACT GTTCAGCCGG CAGGGAAAAC TTCGGCTACA AAAATGGTAC 
CTGGCCACCT CAGACAAGGA GAGGAAGAAG ATGGTCCGAG AGCTCATGCA AGTCGTCCTG 
GCTAGAAAGC CCAAAATGTG CAGCTTCCTG GAGTGGAGGG ACCTCAAAGT TGTCTATAAG 
AGATACGCCA GTCTCTATTT CTGCTGCGCC ATCGAAGGCC AAGACAACGA GCTGATCACA 
CTGGAGCTGA TCCACCGATA CGTAGAGCTC TTGGACAAGT ACTTCGGCAG CGTATGTGAG 
TTGGACATCA TCTTCAACTT TGAGAAAGCC TACTTTATCC TGGACGAGTT TCTGATGGGT 
GGGGATGTCC AGGACACCTC CAAGAAGAGT GTGCTCAAGG CCATTGAGCA GGCTGACCTG 
CTGCAGGAGG AGGATGAGTC GCCGCGCAGT GTCCTGGAGG AGATGGGCCT GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap1s1 ( XM_006504348.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504411.1 Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu36103
Clone ID Related Accession (Same CDS sequence)	XM_006504348.3 , XM_006504348.4
Accession Version	XM_006504348.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	AP-1 complex subunit sigma-1A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504348.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCAGA AGAAAGGTCA GGCCTTAGAG TGCACACCTG TAACCTGGTA CTCAGAGATG 
CGATTCATGC TACTGTTCAG CCGGCAGGGA AAACTTCGGC TACAAAAATG GTACCTGGCC 
ACCTCAGACA AGGAGAGGAA GAAGATGGTC CGAGAGCTCA TGCAAGTCGT CCTGGCTAGA 
AAGCCCAAAA TGTGCAGCTT CCTGGAGTGG AGGGACCTCA AAGTTGTCTA TAAGAGATAC 
GCCAGTCTCT ATTTCTGCTG CGCCATCGAA GGCCAAGACA ACGAGCTGAT CACACTGGAG 
CTGATCCACC GATACGTAGA GCTCTTGGAC AAGTACTTCG GCAGCGTATG TGAGTTGGAC 
ATCATCTTCA ACTTTGAGAA AGCCTACTTT ATCCTGGACG AGTTTCTGAT GGGTGGGGAT 
GTCCAGGACA CCTCCAAGAA GAGTGTGCTC AAGGCCATTG AGCAGGCTGA CCTGCTGCAG 
GAGGAGGATG AGTCGCCGCG CAGTGTCCTG GAGGAGATGG GCCTGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504411.1
CDS	865..1395
Translation	MSQKKGQALECTPVTWYSEMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA

Target ORF information:

RefSeq Version	XM_006504348.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504348.4

ORF Insert Sequence:

ATGTCTCAGA AGAAAGGTCA GGCCTTAGAG TGCACACCTG TAACCTGGTA CTCAGAGATG 
CGATTCATGC TACTGTTCAG CCGGCAGGGA AAACTTCGGC TACAAAAATG GTACCTGGCC 
ACCTCAGACA AGGAGAGGAA GAAGATGGTC CGAGAGCTCA TGCAAGTCGT CCTGGCTAGA 
AAGCCCAAAA TGTGCAGCTT CCTGGAGTGG AGGGACCTCA AAGTTGTCTA TAAGAGATAC 
GCCAGTCTCT ATTTCTGCTG CGCCATCGAA GGCCAAGACA ACGAGCTGAT CACACTGGAG 
CTGATCCACC GATACGTAGA GCTCTTGGAC AAGTACTTCG GCAGCGTATG TGAGTTGGAC 
ATCATCTTCA ACTTTGAGAA AGCCTACTTT ATCCTGGACG AGTTTCTGAT GGGTGGGGAT 
GTCCAGGACA CCTCCAAGAA GAGTGTGCTC AAGGCCATTG AGCAGGCTGA CCTGCTGCAG 
GAGGAGGATG AGTCGCCGCG CAGTGTCCTG GAGGAGATGG GCCTGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway.
Scientific reports629950(2016 Jul)
Candiello E,Kratzke M,Wenzel D,Cassel D,Schu P

?1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue.
Journal of cell science127(Pt 16)3477-87(2014 Aug)
Baltes J,Larsen JV,Radhakrishnan K,Geumann C,Kratzke M,Petersen CM,Schu P

Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: ?1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.
The Journal of neuroscience : the official journal of the Society for Neuroscience34(10)3545-58(2014 Mar)
Moreno E,Moreno-Delgado D,Navarro G,Hoffmann HM,Fuentes S,Rosell-Vilar S,Gasperini P,Rodr?guez-Ruiz M,Medrano M,Mallol J,Cort?s A,Casad? V,Llu?s C,Ferr? S,Ortiz J,Canela E,McCormick PJ

AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory.
The EMBO journal29(8)1318-30(2010 Apr)
Glyvuk N,Tsytsyura Y,Geumann C,D'Hooge R,H?ve J,Kratzke M,Baltes J,Boening D,B?ning D,Klingauf J,Schu P

The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.
Molecular biology of the cell18(5)1887-96(2007 May)
Doray B,Lee I,Knisely J,Bu G,Kornfeld S

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Ap1s1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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