Anxa3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Anxa3
Entrez Gene ID	11745
Full Name	annexin A3
Synonyms	Anx3
General protein information	Preferred Names annexin A3 Names annexin A3 35-alpha calcimedin PAP-III annexin III annexin-3 lipocortin III placental anticoagulant protein III
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 E3\|5 47.29 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_013470.2	NP_038498.2	annexin A3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Anxa3	NP_038498.2
Homo sapiens (human)	ANXA3	NP_005130.1
Pan troglodytes (chimpanzee)	ANXA3	XP_001146085.2
Danio rerio (zebrafish)	anxa3a	NP_001004632.1
Bos taurus (cattle)	ANXA3	NP_001030402.1
Rattus norvegicus (Norway rat)	Anxa3	NP_036955.2
Danio rerio (zebrafish)	anxa3b	NP_001007303.1
	ANXA3	XP_001091995.1
Canis lupus familiaris (dog)	ANXA3	XP_535624.3

Gene Ontology
Bibliography

Related articles in PubMed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Naba A, Clauser KR, Mani DR, Carr SA, Hynes RO
Scientific reports740495(2017 Jan)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Pan QZ, Pan K, Wang QJ, Weng DS, Zhao JJ, Zheng HX, Zhang XF, Jiang SS, Lv L, Tang Y, Li YQ, He J, Liu Q, Chen CL, Zhang HX, Xia JC
Stem cells (Dayton, Ohio)33(2)354-66(2015 Feb)

Annexin A3 Regulates Early Blood Vessel Formation.
Meadows SM, Cleaver O
PloS one10(7)e0132580(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Annexin A3 regulates early blood vessel formation.
Title: Annexin A3 Regulates Early Blood Vessel Formation.

data suggest that annexin A3 is a negative regulator of adipocyte differentiation
Title: Annexin A3 as a negative regulator of adipocyte differentiation.

AnxA3 is not only endogenously expressed in mouse cortical neurons but more importantly, it is transcriptionally up-regulated with onset of lactacystin-mediated death in murine primary cortical neurons.
Title: Annexin A3 is associated with cell death in lactacystin-mediated neuronal injury.

The following Anxa3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Anxa3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15142	NM_013470.2 Latest version!	Mus musculus annexin A3 (Anxa3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Anxa3 ( NM_013470.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038498.2 Mus musculus annexin A3 (Anxa3), mRNA.

Price & Availability↑

CloneID	OMu15142
Clone ID Related Accession (Same CDS sequence)	NM_013470.2
Accession Version	NM_013470.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	annexin A3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK150922.1 and AJ001633.1. On Nov 20, 2007 this sequence version replaced NM_013470.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ001633.1, BC090634.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCTA TCTGGGTTGG ACCTCGAGGA ACCATAAAAG ATTATCCAGG CTTTAGCCCG 
TCGGTGGATG CCGAAGCTAT CCGGAAAGCG ATCAGAGGAC TTGGGACTGA CGAGAAAACC 
CTCATCAACA TTCTGACGGA GCGGTCGAAC GCGCAGCGAC AGCTGATTGT CAAGCAGTAC 
CAAGCAGCGT ATGAACAGGA GCTGAAAGAT GACTTGAAGG GTGATCTCTC TGGCCACTTC 
GAGCACGTCA TGGTGGCTCT TGTTACTGCA CCAGCCCTGT TTGATGCGAA GCAACTGAAG 
AAATCCATGA AGGGAACTGG CACAGATGAA GATGCCCTGA TTGAAATCCT AACAACCAGG 
TCAAGCAGGC AGATGAAGGA AATCTCGCAG GCCTATTATA CAGTGTATAA GAAGAGCCTC 
GGGGATGACA TTAGCTCTGA GACGTCTGGA GACTTCCGGA AAGCTCTGCT GACTCTGGCA 
GATGGTAGAA GAGATGAAAG CCTCAAAGTG GATGAACATC TGGCCAAAAA GGATGCTCAG 
ATCCTCTATA ATGCTGGTGA GAACAAATGG GGCACAGACG AAGACAAATT CACCGAGGTC 
TTGTGTCTAC GGAGCTTCCC GCAGCTGAAA CTAACATTTG ATGAGTACAG AAATATTAGC 
CAGAAGGACA TTGAGGACAG CATTAAAGGA GAATTATCTG GACATTTTGA AGACCTGCTG 
CTGGCCATAG TTCATTGTGC GAGGAACACT CCAGCGTTTT TGGCAGAAAG ACTTCATCAG 
GCTTTGAAGG GTGCTGGAAC AGATGAATTC ACTCTGAACA GAATAATGGT TTCCAGATCA 
GAGATTGATC TTTTGGACAT CAGACATGAG TTCAAGAAGC ACTATGGCTA CTCTCTATAC 
TCGGCCATCC AATCAGATAC TTCTGGAGAC TACAGAACCG TGCTCTTGAA GATCTGTGGA 
GAAGATGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038498.2
CDS	218..1189
Translation	MASIWVGPRGTIKDYPGFSPSVDAEAIRKAIRGLGTDEKTLINILTERSNAQRQLIVKQYQAAYEQELKDDLKGDLSGHFEHVMVALVTAPALFDAKQLKKSMKGTGTDEDALIEILTTRSSRQMKEISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKKDAQILYNAGENKWGTDEDKFTEVLCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVHCARNTPAFLAERLHQALKGAGTDEFTLNRIMVSRSEIDLLDIRHEFKKHYGYSLYSAIQSDTSGDYRTVLLKICGEDD

Target ORF information:

RefSeq Version	NM_013470.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus annexin A3 (Anxa3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013470.2

ORF Insert Sequence:

ATGGCCTCTA TCTGGGTTGG ACCTCGAGGA ACCATAAAAG ATTATCCAGG CTTTAGCCCG 
TCGGTGGATG CCGAAGCTAT CCGGAAAGCG ATCAGAGGAC TTGGGACTGA CGAGAAAACC 
CTCATCAACA TTCTGACGGA GCGGTCGAAC GCGCAGCGAC AGCTGATTGT CAAGCAGTAC 
CAAGCAGCGT ATGAACAGGA GCTGAAAGAT GACTTGAAGG GTGATCTCTC TGGCCACTTC 
GAGCACGTCA TGGTGGCTCT TGTTACTGCA CCAGCCCTGT TTGATGCGAA GCAACTGAAG 
AAATCCATGA AGGGAACTGG CACAGATGAA GATGCCCTGA TTGAAATCCT AACAACCAGG 
TCAAGCAGGC AGATGAAGGA AATCTCGCAG GCCTATTATA CAGTGTATAA GAAGAGCCTC 
GGGGATGACA TTAGCTCTGA GACGTCTGGA GACTTCCGGA AAGCTCTGCT GACTCTGGCA 
GATGGTAGAA GAGATGAAAG CCTCAAAGTG GATGAACATC TGGCCAAAAA GGATGCTCAG 
ATCCTCTATA ATGCTGGTGA GAACAAATGG GGCACAGACG AAGACAAATT CACCGAGGTC 
TTGTGTCTAC GGAGCTTCCC GCAGCTGAAA CTAACATTTG ATGAGTACAG AAATATTAGC 
CAGAAGGACA TTGAGGACAG CATTAAAGGA GAATTATCTG GACATTTTGA AGACCTGCTG 
CTGGCCATAG TTCATTGTGC GAGGAACACT CCAGCGTTTT TGGCAGAAAG ACTTCATCAG 
GCTTTGAAGG GTGCTGGAAC AGATGAATTC ACTCTGAACA GAATAATGGT TTCCAGATCA 
GAGATTGATC TTTTGGACAT CAGACATGAG TTCAAGAAGC ACTATGGCTA CTCTCTATAC 
TCGGCCATCC AATCAGATAC TTCTGGAGAC TACAGAACCG TGCTCTTGAA GATCTGTGGA 
GAAGATGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Scientific reports740495(2017 Jan)
Naba A,Clauser KR,Mani DR,Carr SA,Hynes RO

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Stem cells (Dayton, Ohio)33(2)354-66(2015 Feb)
Pan QZ,Pan K,Wang QJ,Weng DS,Zhao JJ,Zheng HX,Zhang XF,Jiang SS,Lv L,Tang Y,Li YQ,He J,Liu Q,Chen CL,Zhang HX,Xia JC

Annexin A3 Regulates Early Blood Vessel Formation.
PloS one10(7)e0132580(2015)
Meadows SM,Cleaver O

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Anxa3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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