Scgb3a2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scgb3a2
Entrez Gene ID	117158
Full Name	secretoglobin, family 3A, member 2
Synonyms	LuLeu1,Pnsp1,UGRP1,Utgrp1
General protein information	Preferred Names secretoglobin, family 3A, member 2 Names secretoglobin family 3A member 2 pneumo secretory protein 1 uteroglobin related protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 B3

mRNA and Protein(s)

mRNA	Protein	Name
XM_011246811.1	XP_011245113.1	secretoglobin family 3A member 2 isoform X1
NM_001289644.1	NP_001276573.1	secretoglobin family 3A member 2 isoform 2 precursor
NM_001289643.1	NP_001276572.1	secretoglobin family 3A member 2 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SCGB3A2	NP_473364.1
Pan troglodytes (chimpanzee)	SCGB3A2	XP_001160330.1
	SCGB3A2	XP_001102976.1
Canis lupus familiaris (dog)	SCGB3A2	XP_003433811.1
Mus musculus (house mouse)	Scgb3a2	NP_473379.1
Rattus norvegicus (Norway rat)	Scgb3a2	NP_001019454.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.
Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A
Developmental biology423(2)170-188(2017 03)

Secretoglobin Superfamily Protein SCGB3A2 Alleviates House Dust Mite-Induced Allergic Airway Inflammation in Mice.
Yoneda M, Xu L, Kajiyama H, Kawabe S, Paiz J, Ward JM, Kimura S
International archives of allergy and immunology171(1)36-44(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results demonstrate that SCGB3A2 has an anti-inflammatory activity in the HDM-induced allergic airway inflammation model, in which SCGB3A2 may modulate the CCR4-CCL17 pathway.
Title: Secretoglobin Superfamily Protein SCGB3A2 Alleviates House Dust Mite-Induced Allergic Airway Inflammation in Mice.

SCGB3A2 is an anti-fibrotic agent, and suggest a possible therapeutic use of recombinant SCGB3A2 in the treatment of pulmonary fibrosis.
Title: Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice.

The pulmonary fibrosis in the Scgb3a2-null mice was more severe than the wild-type controls, thus establishing that SCGB3A2 has anti-fibrotic activity in vivo.
Title: Secretoglobin 3A2 Exhibits Anti-Fibrotic Activity in Bleomycin-Induced Pulmonary Fibrosis Model Mice.

SCGB3A2 regulates FSH/LH production in the anterior pituitary lobe.
Title: Regulation of LH/FSH expression by secretoglobin 3A2 in the mouse pituitary gland.

The results indicate that the loss of SCGB3A2 function was influenced by a modifier gene(s) in mixed genetic background and suggest that SCGB3A2 has anti-inflammatory property.
Title: Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation.

The following Scgb3a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scgb3a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu23281	NM_001289643.1 Latest version!	Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu72448	XM_011246811.1 Latest version!	Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu23085	NM_001289644.1 Latest version!	Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scgb3a2 ( NM_001289643.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001276572.1 Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu23281
Clone ID Related Accession (Same CDS sequence)	NM_001289643.1
Accession Version	NM_001289643.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	secretoglobin family 3A member 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY120182.1 and AF274960.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF274960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849387, SAMN00849390 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTGG TATCTATCTT TCTGCTGGTG ACCATTGGTA TTTGTGGTTA TTCTGCCACT 
GCCCTTCTCA TCAACCGTCT CCCTGTTGTT GACAAATTAC CTGTACCTTT GGACGACATT 
ATTCCCTCAT TTGATCCCTT GAAGATGCTT CTGAAAACCC TGGGCATTTC TGTAGAACAT 
CTGGTGACAG GACTGAAGAA GTGTGTGGAC GAGCTGGGAC CAGAGGCTTC CGAGGCCGTG 
AAGAAGCTTC TGGTAATTAT AATTTGTTCT TATTTCCCTG GGAGAAGCCT TTGCTACGTG 
AACAACCTCC CATCATTTGA GGCTCTTTCA CACCTGGTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276572.1
CDS	118..459
Translation	MKLVSIFLLVTIGICGYSATALLINRLPVVDKLPVPLDDIIPSFDPLKMLLKTLGISVEHLVTGLKKCVDELGPEASEAVKKLLVIIICSYFPGRSLCYVNNLPSFEALSHLV

Target ORF information:

RefSeq Version	NM_001289643.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289643.1

ORF Insert Sequence:

ATGAAGCTGG TATCTATCTT TCTGCTGGTG ACCATTGGTA TTTGTGGTTA TTCTGCCACT 
GCCCTTCTCA TCAACCGTCT CCCTGTTGTT GACAAATTAC CTGTACCTTT GGACGACATT 
ATTCCCTCAT TTGATCCCTT GAAGATGCTT CTGAAAACCC TGGGCATTTC TGTAGAACAT 
CTGGTGACAG GACTGAAGAA GTGTGTGGAC GAGCTGGGAC CAGAGGCTTC CGAGGCCGTG 
AAGAAGCTTC TGGTAATTAT AATTTGTTCT TATTTCCCTG GGAGAAGCCT TTGCTACGTG 
AACAACCTCC CATCATTTGA GGCTCTTTCA CACCTGGTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scgb3a2 ( XM_011246811.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245113.1 Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu72448
Clone ID Related Accession (Same CDS sequence)	XM_011246811.1
Accession Version	XM_011246811.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 420bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	secretoglobin family 3A member 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGG TATCTATCTT TCTGCTGGTG ACCATTGGTA TTTGTGGTTA TTCTGCCACT 
GCCCTTCTCA TCAACCGTCT CCCTGTTGTT GACAAATTAC CTGTACCTTT GGACGACATT 
ATTCCCTCAT TTGATCCCTT GAAGATGCTT CTGAAAACCC TGGGCATTTC TGTAGAACAT 
CTGGTGACAG GACTGAAGAA GTGTGTGGAC GAGCTGGGAC CAGAGGCTTC CGAGGCCGTG 
AAGAAGCTTC TGGTAATTAT AATTTGTTCT TATTTCCCTG GGAGAAGCCT TTGCTACGTG 
AACAACCTCC CATCATTTGT AAGTGTATTA TTTCTTCCCA TGATATGTGC ATATCCCAGG 
GACTCCAAAA AGCAAACATT TGCATTTATA GAAAGAGTGT TTGAACAGTC TAAGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011245113.1
CDS	138..557
Translation	MKLVSIFLLVTIGICGYSATALLINRLPVVDKLPVPLDDIIPSFDPLKMLLKTLGISVEHLVTGLKKCVDELGPEASEAVKKLLVIIICSYFPGRSLCYVNNLPSFVSVLFLPMICAYPRDSKKQTFAFIERVFEQSKL

Target ORF information:

RefSeq Version	XM_011246811.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246811.1

ORF Insert Sequence:

ATGAAGCTGG TATCTATCTT TCTGCTGGTG ACCATTGGTA TTTGTGGTTA TTCTGCCACT 
GCCCTTCTCA TCAACCGTCT CCCTGTTGTT GACAAATTAC CTGTACCTTT GGACGACATT 
ATTCCCTCAT TTGATCCCTT GAAGATGCTT CTGAAAACCC TGGGCATTTC TGTAGAACAT 
CTGGTGACAG GACTGAAGAA GTGTGTGGAC GAGCTGGGAC CAGAGGCTTC CGAGGCCGTG 
AAGAAGCTTC TGGTAATTAT AATTTGTTCT TATTTCCCTG GGAGAAGCCT TTGCTACGTG 
AACAACCTCC CATCATTTGT AAGTGTATTA TTTCTTCCCA TGATATGTGC ATATCCCAGG 
GACTCCAAAA AGCAAACATT TGCATTTATA GAAAGAGTGT TTGAACAGTC TAAGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scgb3a2 ( NM_001289644.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001276573.1 Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu23085
Clone ID Related Accession (Same CDS sequence)	NM_001289644.1
Accession Version	NM_001289644.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 276bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	secretoglobin family 3A member 2 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY120182.1, AK136373.1 and AF274960.1. On Jan 25, 2014 this sequence version replaced XM_006525525.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC061046.1, AK136373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTGG TATCTATCTT TCTGCTGGTG ACCATTGGTA TTTGTGGTTA TTCTGCCACT 
GCCCTTCTCA TCAACCGTCT CCCTGTTGTT GACAAATTAC CTGTACCTTT GGACGACATT 
ATTCCCTCAT TTGATCCCTT GAAGATGCTT CTGAAAACCC TGGGCATTTC TGTAGAACAT 
CTGGTGACAG GACTGAAGAA GTGTGTGGAC GAGCTGGGAC CAGAGGCTTC CGAGGCCGTG 
AAGAAGCTTC TGGAGGCTCT TTCACACCTG GTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276573.1
CDS	118..393
Translation	MKLVSIFLLVTIGICGYSATALLINRLPVVDKLPVPLDDIIPSFDPLKMLLKTLGISVEHLVTGLKKCVDELGPEASEAVKKLLEALSHLV

Target ORF information:

RefSeq Version	NM_001289644.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus secretoglobin, family 3A, member 2 (Scgb3a2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289644.1

ORF Insert Sequence:

ATGAAGCTGG TATCTATCTT TCTGCTGGTG ACCATTGGTA TTTGTGGTTA TTCTGCCACT 
GCCCTTCTCA TCAACCGTCT CCCTGTTGTT GACAAATTAC CTGTACCTTT GGACGACATT 
ATTCCCTCAT TTGATCCCTT GAAGATGCTT CTGAAAACCC TGGGCATTTC TGTAGAACAT 
CTGGTGACAG GACTGAAGAA GTGTGTGGAC GAGCTGGGAC CAGAGGCTTC CGAGGCCGTG 
AAGAAGCTTC TGGAGGCTCT TTCACACCTG GTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.
Developmental biology423(2)170-188(2017 03)
Stauber M,Weidemann M,Dittrich-Breiholz O,Lobschat K,Alten L,Mai M,Beckers A,Kracht M,Gossler A

Secretoglobin Superfamily Protein SCGB3A2 Alleviates House Dust Mite-Induced Allergic Airway Inflammation in Mice.
International archives of allergy and immunology171(1)36-44(2016)
Yoneda M,Xu L,Kajiyama H,Kawabe S,Paiz J,Ward JM,Kimura S

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Scgb3a2 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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