Angpt4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Angpt4
Entrez Gene ID	11602
Full Name	angiopoietin 4
Synonyms	ANG-3,ANG-4,Agpt4,Ang3
General protein information	Preferred Names angiopoietin 4 Names angiopoietin-4 angiopoietin-3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 G3\|2 74.83 cM
Summary	This gene is a member of the angiopoietin family of secreted growth factors comprising Angiopoietins-1, -2, and -3, all of which bind the TEK Receptor Tyrosine Kinase. Angiopoietin/TEK Receptor Tyrosine Kinase signaling is involved in survival and migration of endothelial cells and regulates vascular remodeling and maintenance of vascular integrity. Angiopoietin/TEK Receptor Tyrosine Kinase signaling is also required for lymphangiogenesis. Family members bind TEK Receptor Tyrosine Kinase as multimeric clusters but their oligomerization properties differ from one another and this is thought to provide a mechanistic basis for their distinct physiologic roles. [provided by RefSeq, Jul 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_009641.1	NP_033771.1	angiopoietin-4 precursor
NM_009641.2	NP_033771.1	angiopoietin-4 precursor

Pathways from BioSystems

Homologies

	ANGPT4	XP_001112522.1
Canis lupus familiaris (dog)	ANGPT4	XP_005634951.1
Gallus gallus (chicken)	ANGPT4	XP_004947203.1
Homo sapiens (human)	ANGPT4	NP_057069.1
Pan troglodytes (chimpanzee)	ANGPT4	XP_003316840.1
Bos taurus (cattle)	ANGPT4	NP_001069951.1
Mus musculus (house mouse)	Angpt4	NP_033771.1
Rattus norvegicus (Norway rat)	Angpt4	NP_001099996.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression profiling of angiogenesis-related genes in brain metastases of lung cancer and melanoma.
Ilhan-Mutlu A, Siehs C, Berghoff AS, Ricken G, Widhalm G, Wagner L, Preusser M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(1)1173-82(2016 Jan)

Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation.
Kesler CT, Pereira ER, Cui CH, Nelson GM, Masuck DJ, Baish JW, Padera TP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology29(9)3668-77(2015 Sep)

Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment.
Brunckhorst MK, Xu Y, Lu R, Yu Q
The American journal of pathology184(8)2285-96(2014 Aug)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ang-4 also promoted survival of LECs. Thus, blocking Ang-4 may prune the draining lymphatic vasculature and decrease interstitial fluid pressure (IFP) by reducing vascular permeability.
Title: Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation.

Angptl4 is a glucocorticoid-responsive mediator of fasting-induced intracellular lipolysis and stimulates cAMP signaling in adipocytes
Title: Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes.

angiopoietin-4 inhibits angiogenesis and reduces interstitial fluid pressure
Title: Angiopoietin-4 inhibits angiogenesis and reduces interstitial fluid pressure.

Angiopoietin-3 binds to the cell membrane via heparan sulfate proteoglycans
Title: Angiopoietin-3 is tethered on the cell surface via heparan sulfate proteoglycans.

Recombinant Ang3 formed disulfide-linked dimers. Ang3 was more potent than Ang4 in phosphorylating Akt in primary cultured mouse lung microvascular endothelial cells. It is a Tie2 agonist & causes corneal angiogenesis.
Title: Biological characterization of angiopoietin-3 and angiopoietin-4.

The following Angpt4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Angpt4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04560	NM_009641.2 Latest version!	Mus musculus angiopoietin 4 (Angpt4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$293.30 $419.00
View Old Accession Versions >>
OMu04560	NM_009641.1	Mus musculus angiopoietin 4 (Angpt4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$293.30 $419.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Angpt4 ( NM_009641.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033771.1 Mus musculus angiopoietin 4 (Angpt4), mRNA.

Price & Availability↑

CloneID	OMu04560
Clone ID Related Accession (Same CDS sequence)	NM_009641.1 , NM_009641.2
Accession Version	NM_009641.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-14
Organism	Mus musculus(House mouse)
Product	angiopoietin-4 precursor
Comment

ATGCTCTGCC AGCCAGCTAT GCTACTAGAT GGCCTCCTCC TGCTGGCCAC CATGGCTGCA 
GCCCAGCACA GAGGGCCAGA AGCCGGTGGG CACCGCCAGA TTCACCAGGT CCGGCGTGGC 
CAGTGCAGCT ACACCTTTGT GGTGCCGGAG CCTGATATCT GCCAGCTGGC GCCGACAGCG 
GCGCCTGAGG CTTTGGGGGG CTCCAATAGC CTCCAGAGGG ACTTGCCTGC CTCGAGGCTG 
CACCTAACAG ACTGGCGAGC CCAGAGGGCC CAGCGGGCCC AGCGTGTGAG CCAGCTGGAG 
AAGATACTAG AGAATAACAC TCAGTGGCTG CTGAAGCTGG AGCAGTCCAT CAAGGTGAAC 
TTGAGGTCAC ACCTGGTGCA GGCCCAGCAG GACACAATCC AGAACCAGAC AACTACCATG 
CTGGCACTGG GTGCCAACCT CATGAACCAG ACCAAAGCTC AGACCCACAA GCTGACTGCT 
GTGGAGGCAC AGGTCCTAAA CCAGACATTG CACATGAAGA CCCAAATGCT GGAGAACTCA 
CTGTCCACCA ACAAGCTGGA GCGGCAGATG CTGATGCAGA GCCGAGAGCT GCAGCGGCTG 
CAGGGTCGCA ACAGGGCCCT GGAGACCAGG CTGCAGGCAC TGGAAGCACA ACATCAGGCC 
CAGCTTAACA GCCTCCAAGA GAAGAGGGAA CAACTGCACA GTCTCCTGGG CCATCAGACC 
GGGACCCTGG CTAACCTGAA GCACAATCTG CACGCTCTCA GCAGCAATTC CAGCTCCCTG 
CAGCAGCAGC AGCAGCAACT GACGGAGTTT GTACAGCGCC TGGTACGGAT TGTAGCCCAG 
GACCAGCATC CGGTTTCCTT AAAGACACCT AAGCCAGTGT TCCAGGACTG TGCAGAGATC 
AAGCGCTCCG GGGTTAATAC CAGCGGTGTC TATACCATCT ATGAGACCAA CATGACAAAG 
CCTCTCAAGG TGTTCTGTGA CATGGAGACT GATGGAGGTG GCTGGACCCT CATCCAGCAC 
CGGGAGGATG GAAGCGTAAA TTTCCAGAGG ACCTGGGAAG AATACAAAGA GGGTTTTGGT 
AATGTGGCCA GAGAGCACTG GCTGGGCAAT GAGGCTGTGC ACCGCCTCAC CAGCAGAACG 
GCCTACTTGC TACGCGTGGA ACTGCATGAC TGGGAAGGCC GCCAGACCTC CATCCAGTAT 
GAGAACTTCC AGCTGGGCAG CGAGAGGCAG CGGTACAGCC TCTCTGTGAA TGACAGCAGC 
AGTTCAGCAG GGCGCAAGAA CAGCCTGGCT CCTCAGGGCA CCAAGTTCAG CACCAAAGAC 
ATGGACAATG ATAACTGCAT GTGTAAATGT GCTCAGATGC TGTCTGGAGG GTGGTGGTTT 
GATGCCTGTG GCCTCTCCAA CCTCAATGGC ATCTACTATT CAGTTCATCA GCACTTGCAC 
AAGATCAATG GCATCCGCTG GCACTACTTC CGAGGCCCCA GCTACTCACT GCACGGCACA 
CGCATGATGC TGAGGCCAAT GGGTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_033771.1

Translation

MLCQPAMLLDGLLLLATMAAAQHRGPEAGGHRQIHQVRRGQCSYTFVVPEPDICQLAPTAAPEALGGSNSLQRDLPASRLHLTDWRAQRAQRAQRVSQLEKILENNTQWLLKLEQSIKVNLRSHLVQAQQDTIQNQTTTMLALGANLMNQTKAQTHKLTAVEAQVLNQTLHMKTQMLENSLSTNKLERQMLMQSRELQRLQGRNRALETRLQALEAQHQAQLNSLQEKREQLHSLLGHQTGTLANLKHNLHALSSNSSSLQQQQQQLTEFVQRLVRIVAQDQHPVSLKTPKPVFQDCAEIKRSGVNTSGVYTIYETNMTKPLKVFCDMETDGGGWTLIQHREDGSVNFQRTWEEYKEGFGNVAREHWLGNEAVHRLTSRTAYLLRVELHDWEGRQTSIQYENFQLGSERQRYSLSVNDSSSSAGRKNSLAPQGTKFSTKDMDNDNCMCKCAQMLSGGWWFDACGLSNLNGIYYSVHQHLHKINGIRWHYFRGPSYSLHGTRMMLRPMGA

Target ORF information:

RefSeq Version	NM_009641.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus angiopoietin 4 (Angpt4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009641.1

ORF Insert Sequence:

ATGCTCTGCC AGCCAGCTAT GCTACTAGAT GGCCTCCTCC TGCTGGCCAC CATGGCTGCA 
GCCCAGCACA GAGGGCCAGA AGCCGGTGGG CACCGCCAGA TTCACCAGGT CCGGCGTGGC 
CAGTGCAGCT ACACCTTTGT GGTGCCGGAG CCTGATATCT GCCAGCTGGC GCCGACAGCG 
GCGCCTGAGG CTTTGGGGGG CTCCAATAGC CTCCAGAGGG ACTTGCCTGC CTCGAGGCTG 
CACCTAACAG ACTGGCGAGC CCAGAGGGCC CAGCGGGCCC AGCGTGTGAG CCAGCTGGAG 
AAGATACTAG AGAATAACAC TCAGTGGCTG CTGAAGCTGG AGCAGTCCAT CAAGGTGAAC 
TTGAGGTCAC ACCTGGTGCA GGCCCAGCAG GACACAATCC AGAACCAGAC AACTACCATG 
CTGGCACTGG GTGCCAACCT CATGAACCAG ACCAAAGCTC AGACCCACAA GCTGACTGCT 
GTGGAGGCAC AGGTCCTAAA CCAGACATTG CACATGAAGA CCCAAATGCT GGAGAACTCA 
CTGTCCACCA ACAAGCTGGA GCGGCAGATG CTGATGCAGA GCCGAGAGCT GCAGCGGCTG 
CAGGGTCGCA ACAGGGCCCT GGAGACCAGG CTGCAGGCAC TGGAAGCACA ACATCAGGCC 
CAGCTTAACA GCCTCCAAGA GAAGAGGGAA CAACTGCACA GTCTCCTGGG CCATCAGACC 
GGGACCCTGG CTAACCTGAA GCACAATCTG CACGCTCTCA GCAGCAATTC CAGCTCCCTG 
CAGCAGCAGC AGCAGCAACT GACGGAGTTT GTACAGCGCC TGGTACGGAT TGTAGCCCAG 
GACCAGCATC CGGTTTCCTT AAAGACACCT AAGCCAGTGT TCCAGGACTG TGCAGAGATC 
AAGCGCTCCG GGGTTAATAC CAGCGGTGTC TATACCATCT ATGAGACCAA CATGACAAAG 
CCTCTCAAGG TGTTCTGTGA CATGGAGACT GATGGAGGTG GCTGGACCCT CATCCAGCAC 
CGGGAGGATG GAAGCGTAAA TTTCCAGAGG ACCTGGGAAG AATACAAAGA GGGTTTTGGT 
AATGTGGCCA GAGAGCACTG GCTGGGCAAT GAGGCTGTGC ACCGCCTCAC CAGCAGAACG 
GCCTACTTGC TACGCGTGGA ACTGCATGAC TGGGAAGGCC GCCAGACCTC CATCCAGTAT 
GAGAACTTCC AGCTGGGCAG CGAGAGGCAG CGGTACAGCC TCTCTGTGAA TGACAGCAGC 
AGTTCAGCAG GGCGCAAGAA CAGCCTGGCT CCTCAGGGCA CCAAGTTCAG CACCAAAGAC 
ATGGACAATG ATAACTGCAT GTGTAAATGT GCTCAGATGC TGTCTGGAGG GTGGTGGTTT 
GATGCCTGTG GCCTCTCCAA CCTCAATGGC ATCTACTATT CAGTTCATCA GCACTTGCAC 
AAGATCAATG GCATCCGCTG GCACTACTTC CGAGGCCCCA GCTACTCACT GCACGGCACA 
CGCATGATGC TGAGGCCAAT GGGTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Angpt4 ( NM_009641.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033771.1 Mus musculus angiopoietin 4 (Angpt4), mRNA.

Price & Availability↑

CloneID	OMu04560
Clone ID Related Accession (Same CDS sequence)	NM_009641.1 , NM_009641.2
Accession Version	NM_009641.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	angiopoietin-4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK132988.1, AF113707.1 and BQ032449.1. On Jul 20, 2016 this sequence version replaced NM_009641.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK132988.1, BC129965.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGCTCTGCC AGCCAGCTAT GCTACTAGAT GGCCTCCTCC TGCTGGCCAC CATGGCTGCA 
GCCCAGCACA GAGGGCCAGA AGCCGGTGGG CACCGCCAGA TTCACCAGGT CCGGCGTGGC 
CAGTGCAGCT ACACCTTTGT GGTGCCGGAG CCTGATATCT GCCAGCTGGC GCCGACAGCG 
GCGCCTGAGG CTTTGGGGGG CTCCAATAGC CTCCAGAGGG ACTTGCCTGC CTCGAGGCTG 
CACCTAACAG ACTGGCGAGC CCAGAGGGCC CAGCGGGCCC AGCGTGTGAG CCAGCTGGAG 
AAGATACTAG AGAATAACAC TCAGTGGCTG CTGAAGCTGG AGCAGTCCAT CAAGGTGAAC 
TTGAGGTCAC ACCTGGTGCA GGCCCAGCAG GACACAATCC AGAACCAGAC AACTACCATG 
CTGGCACTGG GTGCCAACCT CATGAACCAG ACCAAAGCTC AGACCCACAA GCTGACTGCT 
GTGGAGGCAC AGGTCCTAAA CCAGACATTG CACATGAAGA CCCAAATGCT GGAGAACTCA 
CTGTCCACCA ACAAGCTGGA GCGGCAGATG CTGATGCAGA GCCGAGAGCT GCAGCGGCTG 
CAGGGTCGCA ACAGGGCCCT GGAGACCAGG CTGCAGGCAC TGGAAGCACA ACATCAGGCC 
CAGCTTAACA GCCTCCAAGA GAAGAGGGAA CAACTGCACA GTCTCCTGGG CCATCAGACC 
GGGACCCTGG CTAACCTGAA GCACAATCTG CACGCTCTCA GCAGCAATTC CAGCTCCCTG 
CAGCAGCAGC AGCAGCAACT GACGGAGTTT GTACAGCGCC TGGTACGGAT TGTAGCCCAG 
GACCAGCATC CGGTTTCCTT AAAGACACCT AAGCCAGTGT TCCAGGACTG TGCAGAGATC 
AAGCGCTCCG GGGTTAATAC CAGCGGTGTC TATACCATCT ATGAGACCAA CATGACAAAG 
CCTCTCAAGG TGTTCTGTGA CATGGAGACT GATGGAGGTG GCTGGACCCT CATCCAGCAC 
CGGGAGGATG GAAGCGTAAA TTTCCAGAGG ACCTGGGAAG AATACAAAGA GGGTTTTGGT 
AATGTGGCCA GAGAGCACTG GCTGGGCAAT GAGGCTGTGC ACCGCCTCAC CAGCAGAACG 
GCCTACTTGC TACGCGTGGA ACTGCATGAC TGGGAAGGCC GCCAGACCTC CATCCAGTAT 
GAGAACTTCC AGCTGGGCAG CGAGAGGCAG CGGTACAGCC TCTCTGTGAA TGACAGCAGC 
AGTTCAGCAG GGCGCAAGAA CAGCCTGGCT CCTCAGGGCA CCAAGTTCAG CACCAAAGAC 
ATGGACAATG ATAACTGCAT GTGTAAATGT GCTCAGATGC TGTCTGGAGG GTGGTGGTTT 
GATGCCTGTG GCCTCTCCAA CCTCAATGGC ATCTACTATT CAGTTCATCA GCACTTGCAC 
AAGATCAATG GCATCCGCTG GCACTACTTC CGAGGCCCCA GCTACTCACT GCACGGCACA 
CGCATGATGC TGAGGCCAAT GGGTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033771.1
CDS	126..1655
Translation	MLCQPAMLLDGLLLLATMAAAQHRGPEAGGHRQIHQVRRGQCSYTFVVPEPDICQLAPTAAPEALGGSNSLQRDLPASRLHLTDWRAQRAQRAQRVSQLEKILENNTQWLLKLEQSIKVNLRSHLVQAQQDTIQNQTTTMLALGANLMNQTKAQTHKLTAVEAQVLNQTLHMKTQMLENSLSTNKLERQMLMQSRELQRLQGRNRALETRLQALEAQHQAQLNSLQEKREQLHSLLGHQTGTLANLKHNLHALSSNSSSLQQQQQQLTEFVQRLVRIVAQDQHPVSLKTPKPVFQDCAEIKRSGVNTSGVYTIYETNMTKPLKVFCDMETDGGGWTLIQHREDGSVNFQRTWEEYKEGFGNVAREHWLGNEAVHRLTSRTAYLLRVELHDWEGRQTSIQYENFQLGSERQRYSLSVNDSSSSAGRKNSLAPQGTKFSTKDMDNDNCMCKCAQMLSGGWWFDACGLSNLNGIYYSVHQHLHKINGIRWHYFRGPSYSLHGTRMMLRPMGA

Target ORF information:

RefSeq Version	NM_009641.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus angiopoietin 4 (Angpt4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009641.2

ORF Insert Sequence:

ATGCTCTGCC AGCCAGCTAT GCTACTAGAT GGCCTCCTCC TGCTGGCCAC CATGGCTGCA 
GCCCAGCACA GAGGGCCAGA AGCCGGTGGG CACCGCCAGA TTCACCAGGT CCGGCGTGGC 
CAGTGCAGCT ACACCTTTGT GGTGCCGGAG CCTGATATCT GCCAGCTGGC GCCGACAGCG 
GCGCCTGAGG CTTTGGGGGG CTCCAATAGC CTCCAGAGGG ACTTGCCTGC CTCGAGGCTG 
CACCTAACAG ACTGGCGAGC CCAGAGGGCC CAGCGGGCCC AGCGTGTGAG CCAGCTGGAG 
AAGATACTAG AGAATAACAC TCAGTGGCTG CTGAAGCTGG AGCAGTCCAT CAAGGTGAAC 
TTGAGGTCAC ACCTGGTGCA GGCCCAGCAG GACACAATCC AGAACCAGAC AACTACCATG 
CTGGCACTGG GTGCCAACCT CATGAACCAG ACCAAAGCTC AGACCCACAA GCTGACTGCT 
GTGGAGGCAC AGGTCCTAAA CCAGACATTG CACATGAAGA CCCAAATGCT GGAGAACTCA 
CTGTCCACCA ACAAGCTGGA GCGGCAGATG CTGATGCAGA GCCGAGAGCT GCAGCGGCTG 
CAGGGTCGCA ACAGGGCCCT GGAGACCAGG CTGCAGGCAC TGGAAGCACA ACATCAGGCC 
CAGCTTAACA GCCTCCAAGA GAAGAGGGAA CAACTGCACA GTCTCCTGGG CCATCAGACC 
GGGACCCTGG CTAACCTGAA GCACAATCTG CACGCTCTCA GCAGCAATTC CAGCTCCCTG 
CAGCAGCAGC AGCAGCAACT GACGGAGTTT GTACAGCGCC TGGTACGGAT TGTAGCCCAG 
GACCAGCATC CGGTTTCCTT AAAGACACCT AAGCCAGTGT TCCAGGACTG TGCAGAGATC 
AAGCGCTCCG GGGTTAATAC CAGCGGTGTC TATACCATCT ATGAGACCAA CATGACAAAG 
CCTCTCAAGG TGTTCTGTGA CATGGAGACT GATGGAGGTG GCTGGACCCT CATCCAGCAC 
CGGGAGGATG GAAGCGTAAA TTTCCAGAGG ACCTGGGAAG AATACAAAGA GGGTTTTGGT 
AATGTGGCCA GAGAGCACTG GCTGGGCAAT GAGGCTGTGC ACCGCCTCAC CAGCAGAACG 
GCCTACTTGC TACGCGTGGA ACTGCATGAC TGGGAAGGCC GCCAGACCTC CATCCAGTAT 
GAGAACTTCC AGCTGGGCAG CGAGAGGCAG CGGTACAGCC TCTCTGTGAA TGACAGCAGC 
AGTTCAGCAG GGCGCAAGAA CAGCCTGGCT CCTCAGGGCA CCAAGTTCAG CACCAAAGAC 
ATGGACAATG ATAACTGCAT GTGTAAATGT GCTCAGATGC TGTCTGGAGG GTGGTGGTTT 
GATGCCTGTG GCCTCTCCAA CCTCAATGGC ATCTACTATT CAGTTCATCA GCACTTGCAC 
AAGATCAATG GCATCCGCTG GCACTACTTC CGAGGCCCCA GCTACTCACT GCACGGCACA 
CGCATGATGC TGAGGCCAAT GGGTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression profiling of angiogenesis-related genes in brain metastases of lung cancer and melanoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(1)1173-82(2016 Jan)
Ilhan-Mutlu A,Siehs C,Berghoff AS,Ricken G,Widhalm G,Wagner L,Preusser M

Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology29(9)3668-77(2015 Sep)
Kesler CT,Pereira ER,Cui CH,Nelson GM,Masuck DJ,Baish JW,Padera TP

Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment.
The American journal of pathology184(8)2285-96(2014 Aug)
Brunckhorst MK,Xu Y,Lu R,Yu Q

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

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Angpt4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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