Adrb2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adrb2
Entrez Gene ID	11555
Full Name	adrenergic receptor, beta 2
Synonyms	Adrb-2,Badm,Gpcr7
General protein information	Preferred Names adrenergic receptor, beta 2 Names beta-2 adrenergic receptor beta 2-AR beta-2 adrenoceptor beta-2 adrenoreceptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18 E1\|18 35.1 cM
Summary	This intronless gene belongs to the G-protein-coupled receptor superfamily, which includes transmembrane proteins that play a role in signal transduction across biological membranes resulting in a variety of physiological responses. The encoded protein is a beta-2 adrenergic receptor which is activated by catecholamine ligands such as adrenaline and epinephrine. The protein participates in the classical signaling pathway involving G protein, adenylyl cyclase, cAMP (3'-5'-cyclic adenosine monophosphate) and protein kinase A (PKA). In humans, this gene is implicated in susceptibility to nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Apr 2013].

mRNA and Protein(s)

mRNA	Protein	Name
NM_007420.3	NP_031446.2	beta-2 adrenergic receptor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Adrb2	NP_031446.2
Danio rerio (zebrafish)	adrb2b	NP_001082940.1
Pan troglodytes (chimpanzee)	ADRB2	NP_001182193.1
Canis lupus familiaris (dog)	ADRB2	NP_001003234.1
Bos taurus (cattle)	ADRB2	NP_776656.1
Rattus norvegicus (Norway rat)	Adrb2	NP_036624.2
Anopheles gambiae (African malaria mosquito)	GPRNNA2	XP_003436280.1
Xenopus tropicalis (tropical clawed frog)	adrb2	NP_001116897.2
Drosophila melanogaster (fruit fly)	Octbeta2R	NP_001247076.1
Homo sapiens (human)	ADRB2	NP_000015.1
	ADRB2	NP_001036239.1
Gallus gallus (chicken)	ADRB2	XP_004950644.1
Danio rerio (zebrafish)	adrb2a	NP_001096122.1

Gene Ontology

The following Adrb2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adrb2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18406	NM_007420.3 Latest version!	Mus musculus adrenergic receptor, beta 2 (Adrb2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adrb2 ( NM_007420.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031446.2 Mus musculus adrenergic receptor, beta 2 (Adrb2), mRNA.

Price & Availability↑

CloneID	OMu18406
Clone ID Related Accession (Same CDS sequence)	NM_007420.3
Accession Version	NM_007420.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	beta-2 adrenergic receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124430.3, BC032883.1 and BB844430.1. On Apr 17, 2013 this sequence version replaced NM_007420.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## regulatory uORF :: PMID: 8308019 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGCCAC ACGGGAACGA CAGCGACTTC TTGCTGGCAC CCAACGGAAG CCGAGCGCCA 
GACCACGACG TCACTCAGGA ACGGGACGAA GCGTGGGTTG TGGGCATGGC CATCCTCATG 
TCGGTTATCG TCCTGGCCAT CGTGTTTGGC AACGTGCTGG TCATCACAGC CATTGCCAAG 
TTCGAGCGAC TACAAACCGT CACCAACTAC TTCATAATCT CCTTGGCGTG TGCTGATCTA 
GTCATGGGCC TAGCGGTGGT GCCGTTTGGG GCCAGTCACA TCCTTATGAA AATGTGGAAT 
TTTGGCAACT TCTGGTGCGA GTTCTGGACT TCCATTGATG TGTTGTGCGT CACAGCCAGC 
ATCGAGACCC TGTGCGTGAT TGCAGTGGAT CGCTATGTTG CTATCACATC GCCCTTCAAG 
TACCAGAGCC TGCTGACCAA GAATAAGGCC CGAGTGGTCA TCCTGATGGT ATGGATTGTA 
TCTGGCCTTA CCTCCTTTTT GCCTATCCAG ATGCACTGGT ACCGTGCCAC CCACAAGAAA 
GCTATCGATT GTTACACCGA GGAGACTTGC TGTGACTTCT TCACGAACCA GGCCTACGCC 
ATCGCGTCCT CGATTGTGTC TTTCTACGTG CCCCTGGTGG TGATGGTCTT TGTCTATTCC 
CGGGTCTTCC AGGTGGCCAA AAGGCAGCTG CAGAAGATAG ACAAATCTGA AGGAAGATTC 
CACGCCCAAA ACCTCAGCCA GGTGGAGCAG GATGGGCGGA GCGGCCACGG ACTCCGAAGG 
TCCTCCAAGT TCTGCTTGAA AGAGCACAAA GCCCTCAAGA CTTTAGGCAT CATCATGGGC 
ACATTCACCC TCTGCTGGCT GCCCTTCTTC ATTGTCAATA TCGTGCACGT TATCAGGGAC 
AACCTCATCC CTAAGGAAGT TTACATCCTC CTTAACTGGT TGGGCTACGT CAACTCTGCC 
TTCAATCCTC TTATCTACTG TCGGAGTCCA GATTTCAGGA TTGCCTTTCA AGAGCTTCTG 
TGCCTTCGCA GGTCTTCTTC GAAAACCTAT GGGAACGGCT ACTCTAGCAA TAGCAACGGC 
AGAACGGACT ACACAGGGGA GCCAAACACT TGTCAGCTGG GGCAGGAGAG AGAACAGGAA 
CTGCTGTGTG AGGATCCCCC AGGCATGGAA GGCTTTGTGA ACTGTCAAGG TACTGTGCCT 
AGCCTTAGCG TTGACTCCCA AGGAAGGAAC TGTAGTACAA ATGACTCGCC ACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031446.2
CDS	230..1486
Translation	MGPHGNDSDFLLAPNGSRAPDHDVTQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFIISLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKKAIDCYTEETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRDNLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEPNTCQLGQEREQELLCEDPPGMEGFVNCQGTVPSLSVDSQGRNCSTNDSPL

Target ORF information:

RefSeq Version	NM_007420.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus adrenergic receptor, beta 2 (Adrb2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007420.3

ORF Insert Sequence:

ATGGGGCCAC ACGGGAACGA CAGCGACTTC TTGCTGGCAC CCAACGGAAG CCGAGCGCCA 
GACCACGACG TCACTCAGGA ACGGGACGAA GCGTGGGTTG TGGGCATGGC CATCCTCATG 
TCGGTTATCG TCCTGGCCAT CGTGTTTGGC AACGTGCTGG TCATCACAGC CATTGCCAAG 
TTCGAGCGAC TACAAACCGT CACCAACTAC TTCATAATCT CCTTGGCGTG TGCTGATCTA 
GTCATGGGCC TAGCGGTGGT GCCGTTTGGG GCCAGTCACA TCCTTATGAA AATGTGGAAT 
TTTGGCAACT TCTGGTGCGA GTTCTGGACT TCCATTGATG TGTTGTGCGT CACAGCCAGC 
ATCGAGACCC TGTGCGTGAT TGCAGTGGAT CGCTATGTTG CTATCACATC GCCCTTCAAG 
TACCAGAGCC TGCTGACCAA GAATAAGGCC CGAGTGGTCA TCCTGATGGT ATGGATTGTA 
TCTGGCCTTA CCTCCTTTTT GCCTATCCAG ATGCACTGGT ACCGTGCCAC CCACAAGAAA 
GCTATCGATT GTTACACCGA GGAGACTTGC TGTGACTTCT TCACGAACCA GGCCTACGCC 
ATCGCGTCCT CGATTGTGTC TTTCTACGTG CCCCTGGTGG TGATGGTCTT TGTCTATTCC 
CGGGTCTTCC AGGTGGCCAA AAGGCAGCTG CAGAAGATAG ACAAATCTGA AGGAAGATTC 
CACGCCCAAA ACCTCAGCCA GGTGGAGCAG GATGGGCGGA GCGGCCACGG ACTCCGAAGG 
TCCTCCAAGT TCTGCTTGAA AGAGCACAAA GCCCTCAAGA CTTTAGGCAT CATCATGGGC 
ACATTCACCC TCTGCTGGCT GCCCTTCTTC ATTGTCAATA TCGTGCACGT TATCAGGGAC 
AACCTCATCC CTAAGGAAGT TTACATCCTC CTTAACTGGT TGGGCTACGT CAACTCTGCC 
TTCAATCCTC TTATCTACTG TCGGAGTCCA GATTTCAGGA TTGCCTTTCA AGAGCTTCTG 
TGCCTTCGCA GGTCTTCTTC GAAAACCTAT GGGAACGGCT ACTCTAGCAA TAGCAACGGC 
AGAACGGACT ACACAGGGGA GCCAAACACT TGTCAGCTGG GGCAGGAGAG AGAACAGGAA 
CTGCTGTGTG AGGATCCCCC AGGCATGGAA GGCTTTGTGA ACTGTCAAGG TACTGTGCCT 
AGCCTTAGCG TTGACTCCCA AGGAAGGAAC TGTAGTACAA ATGACTCGCC ACTGTAA