Adam15 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adam15
Entrez Gene ID	11490
Full Name	a disintegrin and metallopeptidase domain 15 (metargidin)
Synonyms	AD56,MDC15
General protein information	Preferred Names a disintegrin and metallopeptidase domain 15 (metargidin) Names disintegrin and metalloproteinase domain-containing protein 15 a disintegrin and metalloprotease domain 15 (metargidin) metalloprotease RGD disintegrin protein metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 F1\|3 39.07 cM
Summary	This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. This gene is prominently expressed in vascular cells, the endocardium, hypertrophic cells in developing bone, and specific areas of hippocampus and cerebellum. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Mice lacking the encoded protein have increased bone mass resulting from osteoblast proliferation, and exhibit reduced neovascularization in a mouse model for retinopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing. [provided by RefSeq, May 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_009614.3	NP_033744.1	disintegrin and metalloproteinase domain-containing protein 15 isoform b precursor
NM_001037722.3	NP_001032811.2	disintegrin and metalloproteinase domain-containing protein 15 isoform a preproprotein
XM_006500918.1	XP_006500981.1	disintegrin and metalloproteinase domain-containing protein 15 isoform X1
XM_006500918.2	XP_006500981.1	disintegrin and metalloproteinase domain-containing protein 15 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ADAM15	XP_005622817.1
Rattus norvegicus (Norway rat)	Adam15	NP_064704.1
Danio rerio (zebrafish)	LOC795199	XP_001335318.4
Mus musculus (house mouse)	Adam15	NP_001032811.2
Homo sapiens (human)	ADAM15	NP_997080.1
Bos taurus (cattle)	ADAM15	NP_001192371.1
Pan troglodytes (chimpanzee)	ADAM15	XP_003308454.1
	ADAM15	XP_001112574.1

Gene Ontology
Bibliography

Related articles in PubMed

A disintegrin and metallproteinase?15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis.
Gao J, Zheng W, Wang L, Song B
Molecular medicine reports11(6)4389-96(2015 Jun)

Characterization of oxygen-induced retinopathy in mice carrying an inactivating point mutation in the catalytic site of ADAM15.
Maretzky T, Blobel CP, Guaiquil V
Investigative ophthalmology & visual science55(10)6774-82(2014 Sep)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings indicated that silencing ADAM15 had antiinflammatory effects in FLSs and efficiently inhibited the development of CIA.
Title: A disintegrin and metallproteinase?15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis.

the catalytic activity of ADAM15 is not crucial for its function in promoting pathological neovascularization in the mouse OIR model, most likely because of the very limited substrate repertoire of ADAM15.
Title: Characterization of oxygen-induced retinopathy in mice carrying an inactivating point mutation in the catalytic site of ADAM15.

ADAM15 upregulation contributes to inflammatory lung injury by promoting endothelial hyperpermeability and neutrophil transmigration.
Title: ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.

A disintegrin and metalloproteinase 15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity.
Title: A disintegrin and metalloproteinase 15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity.

Adult Adam15(-/-) mice displayed an increase in bone volume and thickness with an increase in the number and activity of osteoblasts, whereas osteoclasts were apparently unaffected.
Title: Lack of ADAM15 in mice is associated with increased osteoblast function and bone mass.

The following Adam15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adam15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04506	NM_009614.3 Latest version!	Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu12829	NM_001037722.3 Latest version!	Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$510.30 $729.00
OMu31570	XM_006500918.2 Latest version!	Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OMu31570	XM_006500918.1	Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adam15 ( NM_009614.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033744.1 Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu04506
Clone ID Related Accession (Same CDS sequence)	NM_009614.3
Accession Version	NM_009614.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2448bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 15 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY193755.1, AF006196.1 and AW048202.1. On May 5, 2016 this sequence version replaced NM_009614.2. Transcript Variant: This variant (2) lacks multiple in-frame exons in the 3' coding region, compared to variant 1. The resulting protein (isoform b) is shorter than isoform a. This isoform (b) may undergo processing similar to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF006196.1, AK142520.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGCTGG CGCTGCTCTG GGCTCTGGGA CTCCTGGGCG CGGGCAGCCC TCGGCCCTCC 
CCGCCGCTGC CAAATATAGG AGGCACTGAG GAAGAGCAGC AAGCCAGCCC AGAGAGGACG 
CTGAGTGGAT CCATGGAGAG CCGGGTTGTT CAGGACAGCC CCCCAATGAG CCTAGCAGAC 
GTGCTTCAGA CTGGTTTACC TGAGGCCCTG AGGATTTCCT TGGAGCTGGA CAGTGAGAGT 
CATGTCCTGG AGCTTCTACA AAATAGAGAT CTAATCCCTG GCCGCCCAAC TCTGGTGTGG 
TACCAGCCTG ATGGCACCCG AATGGTCAGC GAGGGCTACA GTCTAGAAAA CTGCTGCTAC 
CGAGGACGAG TGCAGGGCCA CCCCAGCTCC TGGGTGTCCC TCTGTGCCTG CTCTGGGATC 
AGGGGGCTCA TTGTCCTGTC CCCAGAGAGA GGCTATACAC TGGAGCTGGG CCCTGGGGAC 
CTTCAGCGTC CTGTCATTTC TCGGATCCAA GACCACCTGT TGCTGGGCCA CACCTGTGCC 
CCAAGCTGGC ATGCCTCTGT GCCCACTCGG GCAGGACCAG ACCTCCTTCT GGAACAGCAT 
CACGCTCACA GGCTTAAGCG AGATGTAGTA ACAGAGACGA AAATTGTGGA GTTGGTGATT 
GTGGCTGATA ATTCAGAGGT CAGAAAGTAC CCTGACTTCC AACAACTGCT GAACCGGACA 
CTAGAAGCGG CTCTCTTGCT AGACACGTTC TTCCAGCCCT TGAATGTCCG GGTAGCCCTT 
GTGGGCCTAG AGGCATGGAC CCAGCACAAC CTGATAGAAA TGAGCTCCAA CCCAGCTGTC 
CTGCTAGACA ACTTCCTCCG CTGGCGCCGG ACAGACTTGC TGCCTCGACT GCCCCATGAC 
AGTGCCCAAC TGGTGACTGT AACTTCCTTC TCTGGTCCCA TGGTGGGCAT GGCCATTCAG 
AATTCCATCT GTTCCCCTGA CTTCTCCGGA GGTGTGAATA TGGACCACTC CACAAGCATC 
TTAGGCGTTG CCTCCTCGAT TGCCCATGAA TTGGGCCACA GTCTGGGTTT GGACCATGAT 
TCTCCCGGGC ACAGCTGTCC CTGTCCAGGT CCAGCCCCGG CTAAGAGCTG CATCATGGAG 
GCCTCCACAG ACTTCCTACC AGGTTTGAAC TTCAGCAACT GCAGCCGACA GGCCCTGGAA 
AAGGCCCTCC TGGAAGGAAT GGGCAGCTGC CTCTTCGAAC GGCAACCCAG CCTGGCCCCT 
ATGTCCTCTT TGTGTGGAAA TATGTTTGTG GACCCCGGAG AGCAGTGTGA CTGTGGCTTC 
CCAGATGAAT GCACTGATCC CTGCTGTGAC CATTTCACCT GCCAGCTGAG GCCAGGAGCG 
CAGTGTGCAT CTGATGGACC CTGTTGTCAA AACTGCAAGT TGCACCCAGC TGGTTGGCTG 
TGCCGCCCTC CCACAGACGA TTGTGATCTG CCTGAGTTCT GCCCAGGAGA TAGCTCTCAG 
TGCCCGTCTG ACATCAGACT TGGGGACGGT GAGCCTTGTG CTAGTGGAGA GGCTGTGTGT 
ATGCATGGGC GCTGTGCCTC CTATGCCCGG CAGTGCCAGT CACTTTGGGG ACCCGGGGCC 
CAGCCTGCTG CGCCACTTTG CCTCCAAACA GCCAACACTC GGGGTAATGC CTTTGGGAGC 
TGTGGGCGCA GCCCTGGTGG TAGCTACATG CCTTGTGCCC CTAGAGATGT CATGTGTGGG 
CAACTGCAGT GCCAGTGGGG TAGGAGCCAG CCTCTGTTGG GCTCAGTCCA AGATCGGCTC 
TCGGAGGTCC TGGAAGCCAA CGGGACACAG TTAAACTGCA GCTGGGTGGA CCTGGACCTG 
GGCAATGATG TGGCCCAGCC TCTTCTGGCT CTGCCTGGCA CTGCCTGTGG TCCTGGCCTG 
GTGTGCATCG GCCACCGATG CCAGCCCGTG GATCTCCTGG GAGCACAGGA ATGTCGAAGA 
AAATGCCACG GCCATGGGGT CTGTGACAGC AGCGGGCACT GCCGCTGTGA AGAGGGCTGG 
GCACCTCCAG ACTGCATGAC CCAGCTCAAA GCAACCAGCT CCCTGACCAC AGGCCTGCTC 
CTCAGCCTCC TGTTGTTATT GGTCCTCGTA CTACTTGGTG CCAGCTACTG GCACCGTGCC 
CGCCTGCATC AGCGGCTCTG CCAGCTTAAG GGATCCAGCT GCCAATATAG GGCACCCCAA 
TCCTGTCCTC CTGAACGACC AGGACCTCCA CAGCGGGCAC AGCAGATGAC AGGCACTAAG 
TCTCAGGGGC CTACCAAACC CCCACCCCCA AGAAAGCCAC TGCCTGCCAA CCCACAGGGC 
CAGCACCCAC CAGGTGACCT GCCTGGCCCA GGAGATGGAA GCTTGCCGCT GGTGGTGCCC 
TCCAGGCCAG CTCCACCACC CCCTGCAGCA TCTTCGCTCT ACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033744.1
CDS	142..2589
Translation	MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTLSGSMESRVVQDSPPMSLADVLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCYRGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLELGPGDLQRPVISRIQDHLLLGHTCAPSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNRTLEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFERQPSLAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWLCRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRRKCHGHGVCDSSGHCRCEEGWAPPDCMTQLKATSSLTTGLLLSLLLLLVLVLLGASYWHRARLHQRLCQLKGSSCQYRAPQSCPPERPGPPQRAQQMTGTKSQGPTKPPPPRKPLPANPQGQHPPGDLPGPGDGSLPLVVPSRPAPPPPAASSLYL

Target ORF information:

RefSeq Version	NM_009614.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009614.3

ORF Insert Sequence:

ATGCGGCTGG CGCTGCTCTG GGCTCTGGGA CTCCTGGGCG CGGGCAGCCC TCGGCCCTCC 
CCGCCGCTGC CAAATATAGG AGGCACTGAG GAAGAGCAGC AAGCCAGCCC AGAGAGGACG 
CTGAGTGGAT CCATGGAGAG CCGGGTTGTT CAGGACAGCC CCCCAATGAG CCTAGCAGAC 
GTGCTTCAGA CTGGTTTACC TGAGGCCCTG AGGATTTCCT TGGAGCTGGA CAGTGAGAGT 
CATGTCCTGG AGCTTCTACA AAATAGAGAT CTAATCCCTG GCCGCCCAAC TCTGGTGTGG 
TACCAGCCTG ATGGCACCCG AATGGTCAGC GAGGGCTACA GTCTAGAAAA CTGCTGCTAC 
CGAGGACGAG TGCAGGGCCA CCCCAGCTCC TGGGTGTCCC TCTGTGCCTG CTCTGGGATC 
AGGGGGCTCA TTGTCCTGTC CCCAGAGAGA GGCTATACAC TGGAGCTGGG CCCTGGGGAC 
CTTCAGCGTC CTGTCATTTC TCGGATCCAA GACCACCTGT TGCTGGGCCA CACCTGTGCC 
CCAAGCTGGC ATGCCTCTGT GCCCACTCGG GCAGGACCAG ACCTCCTTCT GGAACAGCAT 
CACGCTCACA GGCTTAAGCG AGATGTAGTA ACAGAGACGA AAATTGTGGA GTTGGTGATT 
GTGGCTGATA ATTCAGAGGT CAGAAAGTAC CCTGACTTCC AACAACTGCT GAACCGGACA 
CTAGAAGCGG CTCTCTTGCT AGACACGTTC TTCCAGCCCT TGAATGTCCG GGTAGCCCTT 
GTGGGCCTAG AGGCATGGAC CCAGCACAAC CTGATAGAAA TGAGCTCCAA CCCAGCTGTC 
CTGCTAGACA ACTTCCTCCG CTGGCGCCGG ACAGACTTGC TGCCTCGACT GCCCCATGAC 
AGTGCCCAAC TGGTGACTGT AACTTCCTTC TCTGGTCCCA TGGTGGGCAT GGCCATTCAG 
AATTCCATCT GTTCCCCTGA CTTCTCCGGA GGTGTGAATA TGGACCACTC CACAAGCATC 
TTAGGCGTTG CCTCCTCGAT TGCCCATGAA TTGGGCCACA GTCTGGGTTT GGACCATGAT 
TCTCCCGGGC ACAGCTGTCC CTGTCCAGGT CCAGCCCCGG CTAAGAGCTG CATCATGGAG 
GCCTCCACAG ACTTCCTACC AGGTTTGAAC TTCAGCAACT GCAGCCGACA GGCCCTGGAA 
AAGGCCCTCC TGGAAGGAAT GGGCAGCTGC CTCTTCGAAC GGCAACCCAG CCTGGCCCCT 
ATGTCCTCTT TGTGTGGAAA TATGTTTGTG GACCCCGGAG AGCAGTGTGA CTGTGGCTTC 
CCAGATGAAT GCACTGATCC CTGCTGTGAC CATTTCACCT GCCAGCTGAG GCCAGGAGCG 
CAGTGTGCAT CTGATGGACC CTGTTGTCAA AACTGCAAGT TGCACCCAGC TGGTTGGCTG 
TGCCGCCCTC CCACAGACGA TTGTGATCTG CCTGAGTTCT GCCCAGGAGA TAGCTCTCAG 
TGCCCGTCTG ACATCAGACT TGGGGACGGT GAGCCTTGTG CTAGTGGAGA GGCTGTGTGT 
ATGCATGGGC GCTGTGCCTC CTATGCCCGG CAGTGCCAGT CACTTTGGGG ACCCGGGGCC 
CAGCCTGCTG CGCCACTTTG CCTCCAAACA GCCAACACTC GGGGTAATGC CTTTGGGAGC 
TGTGGGCGCA GCCCTGGTGG TAGCTACATG CCTTGTGCCC CTAGAGATGT CATGTGTGGG 
CAACTGCAGT GCCAGTGGGG TAGGAGCCAG CCTCTGTTGG GCTCAGTCCA AGATCGGCTC 
TCGGAGGTCC TGGAAGCCAA CGGGACACAG TTAAACTGCA GCTGGGTGGA CCTGGACCTG 
GGCAATGATG TGGCCCAGCC TCTTCTGGCT CTGCCTGGCA CTGCCTGTGG TCCTGGCCTG 
GTGTGCATCG GCCACCGATG CCAGCCCGTG GATCTCCTGG GAGCACAGGA ATGTCGAAGA 
AAATGCCACG GCCATGGGGT CTGTGACAGC AGCGGGCACT GCCGCTGTGA AGAGGGCTGG 
GCACCTCCAG ACTGCATGAC CCAGCTCAAA GCAACCAGCT CCCTGACCAC AGGCCTGCTC 
CTCAGCCTCC TGTTGTTATT GGTCCTCGTA CTACTTGGTG CCAGCTACTG GCACCGTGCC 
CGCCTGCATC AGCGGCTCTG CCAGCTTAAG GGATCCAGCT GCCAATATAG GGCACCCCAA 
TCCTGTCCTC CTGAACGACC AGGACCTCCA CAGCGGGCAC AGCAGATGAC AGGCACTAAG 
TCTCAGGGGC CTACCAAACC CCCACCCCCA AGAAAGCCAC TGCCTGCCAA CCCACAGGGC 
CAGCACCCAC CAGGTGACCT GCCTGGCCCA GGAGATGGAA GCTTGCCGCT GGTGGTGCCC 
TCCAGGCCAG CTCCACCACC CCCTGCAGCA TCTTCGCTCT ACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adam15 ( NM_001037722.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001032811.2 Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu12829
Clone ID Related Accession (Same CDS sequence)	NM_001037722.3
Accession Version	NM_001037722.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2595bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 15 isoform a preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY193755.1, AK152725.1 and AW048202.1. On May 5, 2016 this sequence version replaced NM_001037722.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.153448.1, SRR1660811.8159.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGCTGG CGCTGCTCTG GGCTCTGGGA CTCCTGGGCG CGGGCAGCCC TCGGCCCTCC 
CCGCCGCTGC CAAATATAGG AGGCACTGAG GAAGAGCAGC AAGCCAGCCC AGAGAGGACG 
CTGAGTGGAT CCATGGAGAG CCGGGTTGTT CAGGACAGCC CCCCAATGAG CCTAGCAGAC 
GTGCTTCAGA CTGGTTTACC TGAGGCCCTG AGGATTTCCT TGGAGCTGGA CAGTGAGAGT 
CATGTCCTGG AGCTTCTACA AAATAGAGAT CTAATCCCTG GCCGCCCAAC TCTGGTGTGG 
TACCAGCCTG ATGGCACCCG AATGGTCAGC GAGGGCTACA GTCTAGAAAA CTGCTGCTAC 
CGAGGACGAG TGCAGGGCCA CCCCAGCTCC TGGGTGTCCC TCTGTGCCTG CTCTGGGATC 
AGGGGGCTCA TTGTCCTGTC CCCAGAGAGA GGCTATACAC TGGAGCTGGG CCCTGGGGAC 
CTTCAGCGTC CTGTCATTTC TCGGATCCAA GACCACCTGT TGCTGGGCCA CACCTGTGCC 
CCAAGCTGGC ATGCCTCTGT GCCCACTCGG GCAGGACCAG ACCTCCTTCT GGAACAGCAT 
CACGCTCACA GGCTTAAGCG AGATGTAGTA ACAGAGACGA AAATTGTGGA GTTGGTGATT 
GTGGCTGATA ATTCAGAGGT CAGAAAGTAC CCTGACTTCC AACAACTGCT GAACCGGACA 
CTAGAAGCGG CTCTCTTGCT AGACACGTTC TTCCAGCCCT TGAATGTCCG GGTAGCCCTT 
GTGGGCCTAG AGGCATGGAC CCAGCACAAC CTGATAGAAA TGAGCTCCAA CCCAGCTGTC 
CTGCTAGACA ACTTCCTCCG CTGGCGCCGG ACAGACTTGC TGCCTCGACT GCCCCATGAC 
AGTGCCCAAC TGGTGACTGT AACTTCCTTC TCTGGTCCCA TGGTGGGCAT GGCCATTCAG 
AATTCCATCT GTTCCCCTGA CTTCTCCGGA GGTGTGAATA TGGACCACTC CACAAGCATC 
TTAGGCGTTG CCTCCTCGAT TGCCCATGAA TTGGGCCACA GTCTGGGTTT GGACCATGAT 
TCTCCCGGGC ACAGCTGTCC CTGTCCAGGT CCAGCCCCGG CTAAGAGCTG CATCATGGAG 
GCCTCCACAG ACTTCCTACC AGGTTTGAAC TTCAGCAACT GCAGCCGACA GGCCCTGGAA 
AAGGCCCTCC TGGAAGGAAT GGGCAGCTGC CTCTTCGAAC GGCAACCCAG CCTGGCCCCT 
ATGTCCTCTT TGTGTGGAAA TATGTTTGTG GACCCCGGAG AGCAGTGTGA CTGTGGCTTC 
CCAGATGAAT GCACTGATCC CTGCTGTGAC CATTTCACCT GCCAGCTGAG GCCAGGAGCG 
CAGTGTGCAT CTGATGGACC CTGTTGTCAA AACTGCAAGT TGCACCCAGC TGGTTGGCTG 
TGCCGCCCTC CCACAGACGA TTGTGATCTG CCTGAGTTCT GCCCAGGAGA TAGCTCTCAG 
TGCCCGTCTG ACATCAGACT TGGGGACGGT GAGCCTTGTG CTAGTGGAGA GGCTGTGTGT 
ATGCATGGGC GCTGTGCCTC CTATGCCCGG CAGTGCCAGT CACTTTGGGG ACCCGGGGCC 
CAGCCTGCTG CGCCACTTTG CCTCCAAACA GCCAACACTC GGGGTAATGC CTTTGGGAGC 
TGTGGGCGCA GCCCTGGTGG TAGCTACATG CCTTGTGCCC CTAGAGATGT CATGTGTGGG 
CAACTGCAGT GCCAGTGGGG TAGGAGCCAG CCTCTGTTGG GCTCAGTCCA AGATCGGCTC 
TCGGAGGTCC TGGAAGCCAA CGGGACACAG TTAAACTGCA GCTGGGTGGA CCTGGACCTG 
GGCAATGATG TGGCCCAGCC TCTTCTGGCT CTGCCTGGCA CTGCCTGTGG TCCTGGCCTG 
GTGTGCATCG GCCACCGATG CCAGCCCGTG GATCTCCTGG GAGCACAGGA ATGTCGAAGA 
AAATGCCACG GCCATGGGGT CTGTGACAGC AGCGGGCACT GCCGCTGTGA AGAGGGCTGG 
GCACCTCCAG ACTGCATGAC CCAGCTCAAA GCAACCAGCT CCCTGACCAC AGGCCTGCTC 
CTCAGCCTCC TGTTGTTATT GGTCCTCGTA CTACTTGGTG CCAGCTACTG GCACCGTGCC 
CGCCTGCATC AGCGGCTCTG CCAGCTTAAG GGATCCAGCT GCCAATATAG GGCACCCCAA 
TCCTGTCCTC CTGAACGACC AGGACCTCCA CAGCGGGCAC AGCAGATGAC AGGCACTAAG 
CAAGCTAGTG TGGTCAGCTT TCCAGTGCCC CCCTCCAGGC CGCTGCCACC TAACCCCGTG 
CCCAAGAAAC TCCAGGCTGC GCTGGCTGAC CGATCCAATC CCCCCACTCG CCCTCTGCCC 
GCTGACCCTG TGGTGAGGCG CCCAAAGTCT CAGGGGCCTA CCAAACCCCC ACCCCCAAGA 
AAGCCACTGC CTGCCAACCC ACAGGGCCAG CACCCACCAG GTGACCTGCC TGGCCCAGGA 
GATGGAAGCT TGCCGCTGGT GGTGCCCTCC AGGCCAGCTC CACCACCCCC TGCAGCATCT 
TCGCTCTACC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032811.2
CDS	142..2736
Translation	MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTLSGSMESRVVQDSPPMSLADVLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCYRGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLELGPGDLQRPVISRIQDHLLLGHTCAPSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNRTLEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFERQPSLAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWLCRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRRKCHGHGVCDSSGHCRCEEGWAPPDCMTQLKATSSLTTGLLLSLLLLLVLVLLGASYWHRARLHQRLCQLKGSSCQYRAPQSCPPERPGPPQRAQQMTGTKQASVVSFPVPPSRPLPPNPVPKKLQAALADRSNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPANPQGQHPPGDLPGPGDGSLPLVVPSRPAPPPPAASSLYL

Target ORF information:

RefSeq Version	NM_001037722.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037722.3

ORF Insert Sequence:

ATGCGGCTGG CGCTGCTCTG GGCTCTGGGA CTCCTGGGCG CGGGCAGCCC TCGGCCCTCC 
CCGCCGCTGC CAAATATAGG AGGCACTGAG GAAGAGCAGC AAGCCAGCCC AGAGAGGACG 
CTGAGTGGAT CCATGGAGAG CCGGGTTGTT CAGGACAGCC CCCCAATGAG CCTAGCAGAC 
GTGCTTCAGA CTGGTTTACC TGAGGCCCTG AGGATTTCCT TGGAGCTGGA CAGTGAGAGT 
CATGTCCTGG AGCTTCTACA AAATAGAGAT CTAATCCCTG GCCGCCCAAC TCTGGTGTGG 
TACCAGCCTG ATGGCACCCG AATGGTCAGC GAGGGCTACA GTCTAGAAAA CTGCTGCTAC 
CGAGGACGAG TGCAGGGCCA CCCCAGCTCC TGGGTGTCCC TCTGTGCCTG CTCTGGGATC 
AGGGGGCTCA TTGTCCTGTC CCCAGAGAGA GGCTATACAC TGGAGCTGGG CCCTGGGGAC 
CTTCAGCGTC CTGTCATTTC TCGGATCCAA GACCACCTGT TGCTGGGCCA CACCTGTGCC 
CCAAGCTGGC ATGCCTCTGT GCCCACTCGG GCAGGACCAG ACCTCCTTCT GGAACAGCAT 
CACGCTCACA GGCTTAAGCG AGATGTAGTA ACAGAGACGA AAATTGTGGA GTTGGTGATT 
GTGGCTGATA ATTCAGAGGT CAGAAAGTAC CCTGACTTCC AACAACTGCT GAACCGGACA 
CTAGAAGCGG CTCTCTTGCT AGACACGTTC TTCCAGCCCT TGAATGTCCG GGTAGCCCTT 
GTGGGCCTAG AGGCATGGAC CCAGCACAAC CTGATAGAAA TGAGCTCCAA CCCAGCTGTC 
CTGCTAGACA ACTTCCTCCG CTGGCGCCGG ACAGACTTGC TGCCTCGACT GCCCCATGAC 
AGTGCCCAAC TGGTGACTGT AACTTCCTTC TCTGGTCCCA TGGTGGGCAT GGCCATTCAG 
AATTCCATCT GTTCCCCTGA CTTCTCCGGA GGTGTGAATA TGGACCACTC CACAAGCATC 
TTAGGCGTTG CCTCCTCGAT TGCCCATGAA TTGGGCCACA GTCTGGGTTT GGACCATGAT 
TCTCCCGGGC ACAGCTGTCC CTGTCCAGGT CCAGCCCCGG CTAAGAGCTG CATCATGGAG 
GCCTCCACAG ACTTCCTACC AGGTTTGAAC TTCAGCAACT GCAGCCGACA GGCCCTGGAA 
AAGGCCCTCC TGGAAGGAAT GGGCAGCTGC CTCTTCGAAC GGCAACCCAG CCTGGCCCCT 
ATGTCCTCTT TGTGTGGAAA TATGTTTGTG GACCCCGGAG AGCAGTGTGA CTGTGGCTTC 
CCAGATGAAT GCACTGATCC CTGCTGTGAC CATTTCACCT GCCAGCTGAG GCCAGGAGCG 
CAGTGTGCAT CTGATGGACC CTGTTGTCAA AACTGCAAGT TGCACCCAGC TGGTTGGCTG 
TGCCGCCCTC CCACAGACGA TTGTGATCTG CCTGAGTTCT GCCCAGGAGA TAGCTCTCAG 
TGCCCGTCTG ACATCAGACT TGGGGACGGT GAGCCTTGTG CTAGTGGAGA GGCTGTGTGT 
ATGCATGGGC GCTGTGCCTC CTATGCCCGG CAGTGCCAGT CACTTTGGGG ACCCGGGGCC 
CAGCCTGCTG CGCCACTTTG CCTCCAAACA GCCAACACTC GGGGTAATGC CTTTGGGAGC 
TGTGGGCGCA GCCCTGGTGG TAGCTACATG CCTTGTGCCC CTAGAGATGT CATGTGTGGG 
CAACTGCAGT GCCAGTGGGG TAGGAGCCAG CCTCTGTTGG GCTCAGTCCA AGATCGGCTC 
TCGGAGGTCC TGGAAGCCAA CGGGACACAG TTAAACTGCA GCTGGGTGGA CCTGGACCTG 
GGCAATGATG TGGCCCAGCC TCTTCTGGCT CTGCCTGGCA CTGCCTGTGG TCCTGGCCTG 
GTGTGCATCG GCCACCGATG CCAGCCCGTG GATCTCCTGG GAGCACAGGA ATGTCGAAGA 
AAATGCCACG GCCATGGGGT CTGTGACAGC AGCGGGCACT GCCGCTGTGA AGAGGGCTGG 
GCACCTCCAG ACTGCATGAC CCAGCTCAAA GCAACCAGCT CCCTGACCAC AGGCCTGCTC 
CTCAGCCTCC TGTTGTTATT GGTCCTCGTA CTACTTGGTG CCAGCTACTG GCACCGTGCC 
CGCCTGCATC AGCGGCTCTG CCAGCTTAAG GGATCCAGCT GCCAATATAG GGCACCCCAA 
TCCTGTCCTC CTGAACGACC AGGACCTCCA CAGCGGGCAC AGCAGATGAC AGGCACTAAG 
CAAGCTAGTG TGGTCAGCTT TCCAGTGCCC CCCTCCAGGC CGCTGCCACC TAACCCCGTG 
CCCAAGAAAC TCCAGGCTGC GCTGGCTGAC CGATCCAATC CCCCCACTCG CCCTCTGCCC 
GCTGACCCTG TGGTGAGGCG CCCAAAGTCT CAGGGGCCTA CCAAACCCCC ACCCCCAAGA 
AAGCCACTGC CTGCCAACCC ACAGGGCCAG CACCCACCAG GTGACCTGCC TGGCCCAGGA 
GATGGAAGCT TGCCGCTGGT GGTGCCCTCC AGGCCAGCTC CACCACCCCC TGCAGCATCT 
TCGCTCTACC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adam15 ( XM_006500918.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006500981.1 Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu31570
Clone ID Related Accession (Same CDS sequence)	XM_006500918.1 , XM_006500918.2
Accession Version	XM_006500918.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2520bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGCTGG CGCTGCTCTG GGCTCTGGGA CTCCTGGGCG CGGGCAGCCC TCGGCCCTCC 
CCGCCGCTGC CAAATATAGG AGGCACTGAG GAAGAGCAGC AAGCCAGCCC AGAGAGGACG 
CTGAGTGGAT CCATGGAGAG CCGGGTTGTT CAGGACAGCC CCCCAATGAG CCTAGCAGAC 
GTGCTTCAGA CTGGTTTACC TGAGGCCCTG AGGATTTCCT TGGAGCTGGA CAGTGAGAGT 
CATGTCCTGG AGCTTCTACA AAATAGAGAT CTAATCCCTG GCCGCCCAAC TCTGGTGTGG 
TACCAGCCTG ATGGCACCCG AATGGTCAGC GAGGGCTACA GTCTAGAAAA CTGCTGCTAC 
CGAGGACGAG TGCAGGGCCA CCCCAGCTCC TGGGTGTCCC TCTGTGCCTG CTCTGGGATC 
AGGGGGCTCA TTGTCCTGTC CCCAGAGAGA GGCTATACAC TGGAGCTGGG CCCTGGGGAC 
CTTCAGCGTC CTGTCATTTC TCGGATCCAA GACCACCTGT TGCTGGGCCA CACCTGTGCC 
CCAAGCTGGC ATGCCTCTGT GCCCACTCGG GCAGGACCAG ACCTCCTTCT GGAACAGCAT 
CACGCTCACA GGCTTAAGCG AGATGTAGTA ACAGAGACGA AAATTGTGGA GTTGGTGATT 
GTGGCTGATA ATTCAGAGGT CAGAAAGTAC CCTGACTTCC AACAACTGCT GAACCGGACA 
CTAGAAGCGG CTCTCTTGCT AGACACGTTC TTCCAGCCCT TGAATGTCCG GGTAGCCCTT 
GTGGGCCTAG AGGCATGGAC CCAGCACAAC CTGATAGAAA TGAGCTCCAA CCCAGCTGTC 
CTGCTAGACA ACTTCCTCCG CTGGCGCCGG ACAGACTTGC TGCCTCGACT GCCCCATGAC 
AGTGCCCAAC TGGTGACTGT AACTTCCTTC TCTGGTCCCA TGGTGGGCAT GGCCATTCAG 
AATTCCATCT GTTCCCCTGA CTTCTCCGGA GGTGTGAATA TGGACCACTC CACAAGCATC 
TTAGGCGTTG CCTCCTCGAT TGCCCATGAA TTGGGCCACA GTCTGGGTTT GGACCATGAT 
TCTCCCGGGC ACAGCTGTCC CTGTCCAGGT CCAGCCCCGG CTAAGAGCTG CATCATGGAG 
GCCTCCACAG ACTTCCTACC AGGTTTGAAC TTCAGCAACT GCAGCCGACA GGCCCTGGAA 
AAGGCCCTCC TGGAAGGAAT GGGCAGCTGC CTCTTCGAAC GGCAACCCAG CCTGGCCCCT 
ATGTCCTCTT TGTGTGGAAA TATGTTTGTG GACCCCGGAG AGCAGTGTGA CTGTGGCTTC 
CCAGATGAAT GCACTGATCC CTGCTGTGAC CATTTCACCT GCCAGCTGAG GCCAGGAGCG 
CAGTGTGCAT CTGATGGACC CTGTTGTCAA AACTGCAAGT TGCACCCAGC TGGTTGGCTG 
TGCCGCCCTC CCACAGACGA TTGTGATCTG CCTGAGTTCT GCCCAGGAGA TAGCTCTCAG 
TGCCCGTCTG ACATCAGACT TGGGGACGGT GAGCCTTGTG CTAGTGGAGA GGCTGTGTGT 
ATGCATGGGC GCTGTGCCTC CTATGCCCGG CAGTGCCAGT CACTTTGGGG ACCCGGGGCC 
CAGCCTGCTG CGCCACTTTG CCTCCAAACA GCCAACACTC GGGGTAATGC CTTTGGGAGC 
TGTGGGCGCA GCCCTGGTGG TAGCTACATG CCTTGTGCCC CTAGAGATGT CATGTGTGGG 
CAACTGCAGT GCCAGTGGGG TAGGAGCCAG CCTCTGTTGG GCTCAGTCCA AGATCGGCTC 
TCGGAGGTCC TGGAAGCCAA CGGGACACAG TTAAACTGCA GCTGGGTGGA CCTGGACCTG 
GGCAATGATG TGGCCCAGCC TCTTCTGGCT CTGCCTGGCA CTGCCTGTGG TCCTGGCCTG 
GTGTGCATCG GCCACCGATG CCAGCCCGTG GATCTCCTGG GAGCACAGGA ATGTCGAAGA 
AAATGCCACG GCCATGGGGT CTGTGACAGC AGCGGGCACT GCCGCTGTGA AGAGGGCTGG 
GCACCTCCAG ACTGCATGAC CCAGCTCAAA GCAACCAGCT CCCTGACCAC AGGCCTGCTC 
CTCAGCCTCC TGTTGTTATT GGTCCTCGTA CTACTTGGTG CCAGCTACTG GCACCGTGCC 
CGCCTGCATC AGCGGCTCTG CCAGCTTAAG GGATCCAGCT GCCAATATAG GGCACCCCAA 
TCCTGTCCTC CTGAACGACC AGGACCTCCA CAGCGGGCAC AGCAGATGAC AGGCACTAAG 
GCTGCGCTGG CTGACCGATC CAATCCCCCC ACTCGCCCTC TGCCCGCTGA CCCTGTGGTG 
AGGCGCCCAA AGTCTCAGGG GCCTACCAAA CCCCCACCCC CAAGAAAGCC ACTGCCTGCC 
AACCCACAGG GCCAGCACCC ACCAGGTGAC CTGCCTGGCC CAGGAGATGG AAGCTTGCCG 
CTGGTGGTGC CCTCCAGGCC AGCTCCACCA CCCCCTGCAG CATCTTCGCT CTACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006500981.1
CDS	110..2629
Translation	MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTLSGSMESRVVQDSPPMSLADVLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCYRGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLELGPGDLQRPVISRIQDHLLLGHTCAPSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNRTLEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFERQPSLAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWLCRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRRKCHGHGVCDSSGHCRCEEGWAPPDCMTQLKATSSLTTGLLLSLLLLLVLVLLGASYWHRARLHQRLCQLKGSSCQYRAPQSCPPERPGPPQRAQQMTGTKAALADRSNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPANPQGQHPPGDLPGPGDGSLPLVVPSRPAPPPPAASSLYL

Target ORF information:

RefSeq Version	XM_006500918.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006500918.1

ORF Insert Sequence:

ATGCGGCTGG CGCTGCTCTG GGCTCTGGGA CTCCTGGGCG CGGGCAGCCC TCGGCCCTCC 
CCGCCGCTGC CAAATATAGG AGGCACTGAG GAAGAGCAGC AAGCCAGCCC AGAGAGGACG 
CTGAGTGGAT CCATGGAGAG CCGGGTTGTT CAGGACAGCC CCCCAATGAG CCTAGCAGAC 
GTGCTTCAGA CTGGTTTACC TGAGGCCCTG AGGATTTCCT TGGAGCTGGA CAGTGAGAGT 
CATGTCCTGG AGCTTCTACA AAATAGAGAT CTAATCCCTG GCCGCCCAAC TCTGGTGTGG 
TACCAGCCTG ATGGCACCCG AATGGTCAGC GAGGGCTACA GTCTAGAAAA CTGCTGCTAC 
CGAGGACGAG TGCAGGGCCA CCCCAGCTCC TGGGTGTCCC TCTGTGCCTG CTCTGGGATC 
AGGGGGCTCA TTGTCCTGTC CCCAGAGAGA GGCTATACAC TGGAGCTGGG CCCTGGGGAC 
CTTCAGCGTC CTGTCATTTC TCGGATCCAA GACCACCTGT TGCTGGGCCA CACCTGTGCC 
CCAAGCTGGC ATGCCTCTGT GCCCACTCGG GCAGGACCAG ACCTCCTTCT GGAACAGCAT 
CACGCTCACA GGCTTAAGCG AGATGTAGTA ACAGAGACGA AAATTGTGGA GTTGGTGATT 
GTGGCTGATA ATTCAGAGGT CAGAAAGTAC CCTGACTTCC AACAACTGCT GAACCGGACA 
CTAGAAGCGG CTCTCTTGCT AGACACGTTC TTCCAGCCCT TGAATGTCCG GGTAGCCCTT 
GTGGGCCTAG AGGCATGGAC CCAGCACAAC CTGATAGAAA TGAGCTCCAA CCCAGCTGTC 
CTGCTAGACA ACTTCCTCCG CTGGCGCCGG ACAGACTTGC TGCCTCGACT GCCCCATGAC 
AGTGCCCAAC TGGTGACTGT AACTTCCTTC TCTGGTCCCA TGGTGGGCAT GGCCATTCAG 
AATTCCATCT GTTCCCCTGA CTTCTCCGGA GGTGTGAATA TGGACCACTC CACAAGCATC 
TTAGGCGTTG CCTCCTCGAT TGCCCATGAA TTGGGCCACA GTCTGGGTTT GGACCATGAT 
TCTCCCGGGC ACAGCTGTCC CTGTCCAGGT CCAGCCCCGG CTAAGAGCTG CATCATGGAG 
GCCTCCACAG ACTTCCTACC AGGTTTGAAC TTCAGCAACT GCAGCCGACA GGCCCTGGAA 
AAGGCCCTCC TGGAAGGAAT GGGCAGCTGC CTCTTCGAAC GGCAACCCAG CCTGGCCCCT 
ATGTCCTCTT TGTGTGGAAA TATGTTTGTG GACCCCGGAG AGCAGTGTGA CTGTGGCTTC 
CCAGATGAAT GCACTGATCC CTGCTGTGAC CATTTCACCT GCCAGCTGAG GCCAGGAGCG 
CAGTGTGCAT CTGATGGACC CTGTTGTCAA AACTGCAAGT TGCACCCAGC TGGTTGGCTG 
TGCCGCCCTC CCACAGACGA TTGTGATCTG CCTGAGTTCT GCCCAGGAGA TAGCTCTCAG 
TGCCCGTCTG ACATCAGACT TGGGGACGGT GAGCCTTGTG CTAGTGGAGA GGCTGTGTGT 
ATGCATGGGC GCTGTGCCTC CTATGCCCGG CAGTGCCAGT CACTTTGGGG ACCCGGGGCC 
CAGCCTGCTG CGCCACTTTG CCTCCAAACA GCCAACACTC GGGGTAATGC CTTTGGGAGC 
TGTGGGCGCA GCCCTGGTGG TAGCTACATG CCTTGTGCCC CTAGAGATGT CATGTGTGGG 
CAACTGCAGT GCCAGTGGGG TAGGAGCCAG CCTCTGTTGG GCTCAGTCCA AGATCGGCTC 
TCGGAGGTCC TGGAAGCCAA CGGGACACAG TTAAACTGCA GCTGGGTGGA CCTGGACCTG 
GGCAATGATG TGGCCCAGCC TCTTCTGGCT CTGCCTGGCA CTGCCTGTGG TCCTGGCCTG 
GTGTGCATCG GCCACCGATG CCAGCCCGTG GATCTCCTGG GAGCACAGGA ATGTCGAAGA 
AAATGCCACG GCCATGGGGT CTGTGACAGC AGCGGGCACT GCCGCTGTGA AGAGGGCTGG 
GCACCTCCAG ACTGCATGAC CCAGCTCAAA GCAACCAGCT CCCTGACCAC AGGCCTGCTC 
CTCAGCCTCC TGTTGTTATT GGTCCTCGTA CTACTTGGTG CCAGCTACTG GCACCGTGCC 
CGCCTGCATC AGCGGCTCTG CCAGCTTAAG GGATCCAGCT GCCAATATAG GGCACCCCAA 
TCCTGTCCTC CTGAACGACC AGGACCTCCA CAGCGGGCAC AGCAGATGAC AGGCACTAAG 
GCTGCGCTGG CTGACCGATC CAATCCCCCC ACTCGCCCTC TGCCCGCTGA CCCTGTGGTG 
AGGCGCCCAA AGTCTCAGGG GCCTACCAAA CCCCCACCCC CAAGAAAGCC ACTGCCTGCC 
AACCCACAGG GCCAGCACCC ACCAGGTGAC CTGCCTGGCC CAGGAGATGG AAGCTTGCCG 
CTGGTGGTGC CCTCCAGGCC AGCTCCACCA CCCCCTGCAG CATCTTCGCT CTACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adam15 ( XM_006500918.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006500981.1 Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu31570
Clone ID Related Accession (Same CDS sequence)	XM_006500918.1 , XM_006500918.2
Accession Version	XM_006500918.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2520bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006500918.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGCTGG CGCTGCTCTG GGCTCTGGGA CTCCTGGGCG CGGGCAGCCC TCGGCCCTCC 
CCGCCGCTGC CAAATATAGG AGGCACTGAG GAAGAGCAGC AAGCCAGCCC AGAGAGGACG 
CTGAGTGGAT CCATGGAGAG CCGGGTTGTT CAGGACAGCC CCCCAATGAG CCTAGCAGAC 
GTGCTTCAGA CTGGTTTACC TGAGGCCCTG AGGATTTCCT TGGAGCTGGA CAGTGAGAGT 
CATGTCCTGG AGCTTCTACA AAATAGAGAT CTAATCCCTG GCCGCCCAAC TCTGGTGTGG 
TACCAGCCTG ATGGCACCCG AATGGTCAGC GAGGGCTACA GTCTAGAAAA CTGCTGCTAC 
CGAGGACGAG TGCAGGGCCA CCCCAGCTCC TGGGTGTCCC TCTGTGCCTG CTCTGGGATC 
AGGGGGCTCA TTGTCCTGTC CCCAGAGAGA GGCTATACAC TGGAGCTGGG CCCTGGGGAC 
CTTCAGCGTC CTGTCATTTC TCGGATCCAA GACCACCTGT TGCTGGGCCA CACCTGTGCC 
CCAAGCTGGC ATGCCTCTGT GCCCACTCGG GCAGGACCAG ACCTCCTTCT GGAACAGCAT 
CACGCTCACA GGCTTAAGCG AGATGTAGTA ACAGAGACGA AAATTGTGGA GTTGGTGATT 
GTGGCTGATA ATTCAGAGGT CAGAAAGTAC CCTGACTTCC AACAACTGCT GAACCGGACA 
CTAGAAGCGG CTCTCTTGCT AGACACGTTC TTCCAGCCCT TGAATGTCCG GGTAGCCCTT 
GTGGGCCTAG AGGCATGGAC CCAGCACAAC CTGATAGAAA TGAGCTCCAA CCCAGCTGTC 
CTGCTAGACA ACTTCCTCCG CTGGCGCCGG ACAGACTTGC TGCCTCGACT GCCCCATGAC 
AGTGCCCAAC TGGTGACTGT AACTTCCTTC TCTGGTCCCA TGGTGGGCAT GGCCATTCAG 
AATTCCATCT GTTCCCCTGA CTTCTCCGGA GGTGTGAATA TGGACCACTC CACAAGCATC 
TTAGGCGTTG CCTCCTCGAT TGCCCATGAA TTGGGCCACA GTCTGGGTTT GGACCATGAT 
TCTCCCGGGC ACAGCTGTCC CTGTCCAGGT CCAGCCCCGG CTAAGAGCTG CATCATGGAG 
GCCTCCACAG ACTTCCTACC AGGTTTGAAC TTCAGCAACT GCAGCCGACA GGCCCTGGAA 
AAGGCCCTCC TGGAAGGAAT GGGCAGCTGC CTCTTCGAAC GGCAACCCAG CCTGGCCCCT 
ATGTCCTCTT TGTGTGGAAA TATGTTTGTG GACCCCGGAG AGCAGTGTGA CTGTGGCTTC 
CCAGATGAAT GCACTGATCC CTGCTGTGAC CATTTCACCT GCCAGCTGAG GCCAGGAGCG 
CAGTGTGCAT CTGATGGACC CTGTTGTCAA AACTGCAAGT TGCACCCAGC TGGTTGGCTG 
TGCCGCCCTC CCACAGACGA TTGTGATCTG CCTGAGTTCT GCCCAGGAGA TAGCTCTCAG 
TGCCCGTCTG ACATCAGACT TGGGGACGGT GAGCCTTGTG CTAGTGGAGA GGCTGTGTGT 
ATGCATGGGC GCTGTGCCTC CTATGCCCGG CAGTGCCAGT CACTTTGGGG ACCCGGGGCC 
CAGCCTGCTG CGCCACTTTG CCTCCAAACA GCCAACACTC GGGGTAATGC CTTTGGGAGC 
TGTGGGCGCA GCCCTGGTGG TAGCTACATG CCTTGTGCCC CTAGAGATGT CATGTGTGGG 
CAACTGCAGT GCCAGTGGGG TAGGAGCCAG CCTCTGTTGG GCTCAGTCCA AGATCGGCTC 
TCGGAGGTCC TGGAAGCCAA CGGGACACAG TTAAACTGCA GCTGGGTGGA CCTGGACCTG 
GGCAATGATG TGGCCCAGCC TCTTCTGGCT CTGCCTGGCA CTGCCTGTGG TCCTGGCCTG 
GTGTGCATCG GCCACCGATG CCAGCCCGTG GATCTCCTGG GAGCACAGGA ATGTCGAAGA 
AAATGCCACG GCCATGGGGT CTGTGACAGC AGCGGGCACT GCCGCTGTGA AGAGGGCTGG 
GCACCTCCAG ACTGCATGAC CCAGCTCAAA GCAACCAGCT CCCTGACCAC AGGCCTGCTC 
CTCAGCCTCC TGTTGTTATT GGTCCTCGTA CTACTTGGTG CCAGCTACTG GCACCGTGCC 
CGCCTGCATC AGCGGCTCTG CCAGCTTAAG GGATCCAGCT GCCAATATAG GGCACCCCAA 
TCCTGTCCTC CTGAACGACC AGGACCTCCA CAGCGGGCAC AGCAGATGAC AGGCACTAAG 
GCTGCGCTGG CTGACCGATC CAATCCCCCC ACTCGCCCTC TGCCCGCTGA CCCTGTGGTG 
AGGCGCCCAA AGTCTCAGGG GCCTACCAAA CCCCCACCCC CAAGAAAGCC ACTGCCTGCC 
AACCCACAGG GCCAGCACCC ACCAGGTGAC CTGCCTGGCC CAGGAGATGG AAGCTTGCCG 
CTGGTGGTGC CCTCCAGGCC AGCTCCACCA CCCCCTGCAG CATCTTCGCT CTACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006500981.1
CDS	141..2660
Translation	MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTLSGSMESRVVQDSPPMSLADVLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCYRGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLELGPGDLQRPVISRIQDHLLLGHTCAPSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNRTLEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFERQPSLAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWLCRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRRKCHGHGVCDSSGHCRCEEGWAPPDCMTQLKATSSLTTGLLLSLLLLLVLVLLGASYWHRARLHQRLCQLKGSSCQYRAPQSCPPERPGPPQRAQQMTGTKAALADRSNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPANPQGQHPPGDLPGPGDGSLPLVVPSRPAPPPPAASSLYL

Target ORF information:

RefSeq Version	XM_006500918.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006500918.2

ORF Insert Sequence:

ATGCGGCTGG CGCTGCTCTG GGCTCTGGGA CTCCTGGGCG CGGGCAGCCC TCGGCCCTCC 
CCGCCGCTGC CAAATATAGG AGGCACTGAG GAAGAGCAGC AAGCCAGCCC AGAGAGGACG 
CTGAGTGGAT CCATGGAGAG CCGGGTTGTT CAGGACAGCC CCCCAATGAG CCTAGCAGAC 
GTGCTTCAGA CTGGTTTACC TGAGGCCCTG AGGATTTCCT TGGAGCTGGA CAGTGAGAGT 
CATGTCCTGG AGCTTCTACA AAATAGAGAT CTAATCCCTG GCCGCCCAAC TCTGGTGTGG 
TACCAGCCTG ATGGCACCCG AATGGTCAGC GAGGGCTACA GTCTAGAAAA CTGCTGCTAC 
CGAGGACGAG TGCAGGGCCA CCCCAGCTCC TGGGTGTCCC TCTGTGCCTG CTCTGGGATC 
AGGGGGCTCA TTGTCCTGTC CCCAGAGAGA GGCTATACAC TGGAGCTGGG CCCTGGGGAC 
CTTCAGCGTC CTGTCATTTC TCGGATCCAA GACCACCTGT TGCTGGGCCA CACCTGTGCC 
CCAAGCTGGC ATGCCTCTGT GCCCACTCGG GCAGGACCAG ACCTCCTTCT GGAACAGCAT 
CACGCTCACA GGCTTAAGCG AGATGTAGTA ACAGAGACGA AAATTGTGGA GTTGGTGATT 
GTGGCTGATA ATTCAGAGGT CAGAAAGTAC CCTGACTTCC AACAACTGCT GAACCGGACA 
CTAGAAGCGG CTCTCTTGCT AGACACGTTC TTCCAGCCCT TGAATGTCCG GGTAGCCCTT 
GTGGGCCTAG AGGCATGGAC CCAGCACAAC CTGATAGAAA TGAGCTCCAA CCCAGCTGTC 
CTGCTAGACA ACTTCCTCCG CTGGCGCCGG ACAGACTTGC TGCCTCGACT GCCCCATGAC 
AGTGCCCAAC TGGTGACTGT AACTTCCTTC TCTGGTCCCA TGGTGGGCAT GGCCATTCAG 
AATTCCATCT GTTCCCCTGA CTTCTCCGGA GGTGTGAATA TGGACCACTC CACAAGCATC 
TTAGGCGTTG CCTCCTCGAT TGCCCATGAA TTGGGCCACA GTCTGGGTTT GGACCATGAT 
TCTCCCGGGC ACAGCTGTCC CTGTCCAGGT CCAGCCCCGG CTAAGAGCTG CATCATGGAG 
GCCTCCACAG ACTTCCTACC AGGTTTGAAC TTCAGCAACT GCAGCCGACA GGCCCTGGAA 
AAGGCCCTCC TGGAAGGAAT GGGCAGCTGC CTCTTCGAAC GGCAACCCAG CCTGGCCCCT 
ATGTCCTCTT TGTGTGGAAA TATGTTTGTG GACCCCGGAG AGCAGTGTGA CTGTGGCTTC 
CCAGATGAAT GCACTGATCC CTGCTGTGAC CATTTCACCT GCCAGCTGAG GCCAGGAGCG 
CAGTGTGCAT CTGATGGACC CTGTTGTCAA AACTGCAAGT TGCACCCAGC TGGTTGGCTG 
TGCCGCCCTC CCACAGACGA TTGTGATCTG CCTGAGTTCT GCCCAGGAGA TAGCTCTCAG 
TGCCCGTCTG ACATCAGACT TGGGGACGGT GAGCCTTGTG CTAGTGGAGA GGCTGTGTGT 
ATGCATGGGC GCTGTGCCTC CTATGCCCGG CAGTGCCAGT CACTTTGGGG ACCCGGGGCC 
CAGCCTGCTG CGCCACTTTG CCTCCAAACA GCCAACACTC GGGGTAATGC CTTTGGGAGC 
TGTGGGCGCA GCCCTGGTGG TAGCTACATG CCTTGTGCCC CTAGAGATGT CATGTGTGGG 
CAACTGCAGT GCCAGTGGGG TAGGAGCCAG CCTCTGTTGG GCTCAGTCCA AGATCGGCTC 
TCGGAGGTCC TGGAAGCCAA CGGGACACAG TTAAACTGCA GCTGGGTGGA CCTGGACCTG 
GGCAATGATG TGGCCCAGCC TCTTCTGGCT CTGCCTGGCA CTGCCTGTGG TCCTGGCCTG 
GTGTGCATCG GCCACCGATG CCAGCCCGTG GATCTCCTGG GAGCACAGGA ATGTCGAAGA 
AAATGCCACG GCCATGGGGT CTGTGACAGC AGCGGGCACT GCCGCTGTGA AGAGGGCTGG 
GCACCTCCAG ACTGCATGAC CCAGCTCAAA GCAACCAGCT CCCTGACCAC AGGCCTGCTC 
CTCAGCCTCC TGTTGTTATT GGTCCTCGTA CTACTTGGTG CCAGCTACTG GCACCGTGCC 
CGCCTGCATC AGCGGCTCTG CCAGCTTAAG GGATCCAGCT GCCAATATAG GGCACCCCAA 
TCCTGTCCTC CTGAACGACC AGGACCTCCA CAGCGGGCAC AGCAGATGAC AGGCACTAAG 
GCTGCGCTGG CTGACCGATC CAATCCCCCC ACTCGCCCTC TGCCCGCTGA CCCTGTGGTG 
AGGCGCCCAA AGTCTCAGGG GCCTACCAAA CCCCCACCCC CAAGAAAGCC ACTGCCTGCC 
AACCCACAGG GCCAGCACCC ACCAGGTGAC CTGCCTGGCC CAGGAGATGG AAGCTTGCCG 
CTGGTGGTGC CCTCCAGGCC AGCTCCACCA CCCCCTGCAG CATCTTCGCT CTACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A disintegrin and metallproteinase?15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis.
Molecular medicine reports11(6)4389-96(2015 Jun)
Gao J,Zheng W,Wang L,Song B

Characterization of oxygen-induced retinopathy in mice carrying an inactivating point mutation in the catalytic site of ADAM15.
Investigative ophthalmology & visual science55(10)6774-82(2014 Sep)
Maretzky T,Blobel CP,Guaiquil V

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

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Adam15 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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