Acvrl1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Acvrl1
Entrez Gene ID	11482
Full Name	activin A receptor, type II-like 1
Synonyms	AI115505,AI427544,Acvrlk1,Alk1
General protein information	Preferred Names activin A receptor, type II-like 1 Names serine/threonine-protein kinase receptor R3 SKR3 TGF-B superfamily receptor type I TSR-I activin receptor-like kinase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001277255.1	NP_001264184.1	serine/threonine-protein kinase receptor R3 isoform b
NM_001277258.1	NP_001264187.1	serine/threonine-protein kinase receptor R3 isoform a precursor
NM_009612.3	NP_033742.2	serine/threonine-protein kinase receptor R3 isoform a precursor
NM_001277259.1	NP_001264188.1	serine/threonine-protein kinase receptor R3 isoform a precursor
NM_001277257.1	NP_001264186.1	serine/threonine-protein kinase receptor R3 isoform a precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ACVRL1	XP_001145609.1
	ACVRL1	XP_001091113.1
Rattus norvegicus (Norway rat)	Acvrl1	NP_071886.1
Homo sapiens (human)	ACVRL1	NP_001070869.1
Bos taurus (cattle)	ACVRL1	NP_001076948.1
Canis lupus familiaris (dog)	ACVRL1	XP_005636859.1
Mus musculus (house mouse)	Acvrl1	NP_001264184.1
Gallus gallus (chicken)	ACVRL1	XP_003643441.2
Danio rerio (zebrafish)	acvrl1	NP_705929.1
Xenopus tropicalis (tropical clawed frog)	LOC100493282	XP_002935162.2

Gene Ontology
Bibliography

Related articles in PubMed

The TGF? pathway is a key player for the endothelial-to-hematopoietic transition in the embryonic aorta.
Lempereur A, Canto PY, Richard C, Martin S, Thalgott J, Raymond K, Lebrin F, Drevon C, Jaffredo T
Developmental biology(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these studies characterize an accessory TGF-beta-stimulated BMP R-Smad signaling mechanism in interstitial cells of the developing lung.
Title: Transforming growth factor-? stimulates Smad1/5 signaling in pulmonary artery smooth muscle cells and fibroblasts of the newborn mouse through ALK1.

CD109 differentially regulates TGF-beta-induced ALK1-Smad1/5 versus ALK5-Smad2/3 pathways, leading to decreased extracellular matrix production in the skin; epidermal CD109 expression regulates dermal function through a paracrine mechanism
Title: Overexpression of CD109 in the Epidermis Differentially Regulates ALK1 Versus ALK5 Signaling and Modulates Extracellular Matrix Synthesis in the Skin.

These data indicate that both Itgb8 and Alk1 are important in maintaining normal cerebral angiogenesis in response to VEGF. Itgb8 deficiency enhances the formation of dysplastic vessels and hemorrhage in Alk1 (+/-) mice.
Title: Integrin ?8 Deletion Enhances Vascular Dysplasia and Hemorrhage in the Brain of Adult Alk1 Heterozygous Mice.

he results of the present study demonstrated that BMP9 promoted the osteoclast differentiation of osteoclast precursors via binding to the ALK1 receptor on the cell surface, and inhibiting the ERK1/2 signaling pathways in the cell
Title: Bone morphogenetic protein?9 promotes the differentiation of mouse spleen macrophages into osteoclasts via the ALK1 receptor and ERK 1/2 pathways in?vitro.

this study demonstrates that ACVRL1 signaling plays a pivotal role whereby it suppresses plasmacytoid dendritic cell development while enhancing that of CD8alpha(+) dendritic cells, thus contributing to DC diversity development.
Title: Cutting Edge: ACVRL1 Signaling Augments CD8?+ Dendritic Cell Development.

The following Acvrl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Acvrl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19885	NM_001277255.1 Latest version!	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu19836	NM_001277259.1 Latest version!	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu19836	NM_001277257.1 Latest version!	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu19836	NM_009612.3 Latest version!	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu19836	NM_001277258.1 Latest version!	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Acvrl1 ( NM_001277255.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001264184.1 Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu19885
Clone ID Related Accession (Same CDS sequence)	NM_001277255.1
Accession Version	NM_001277255.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase receptor R3 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC104834.4, BB869400.1 and AK134712.1. Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence and uses an upstream in-frame AUG translation start codon compared to variant 1. The resulting isoform (b) is longer at the N-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849387, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGGAA ATCTCACCAC ATCTCTTCTC CTATCTCCAA GGACCATGAC CTTGGGGAGC 
TTCAGAAGGG GCCTTTTGAT GCTGTCGGTG GCCTTTGGCC TAACCAGGGG AGACTTGGCG 
AAGCCTTCCA AGCTGGTGAA CTGCACTTGT GAGAGCCCAC ACTGCAAGAG ACCATTCTGC 
CAGGGGTCAT GGTGCACAGT GGTGCTGGTT CGGGAGCAGG GCAGGCACCC CCAGGTCTAT 
CGGGGCTGCG GGAGCCTGAA CCAGGAGCTC TGCTTGGGAC GTCCCACAGA GTTTCTGAAC 
CATCACTGCT GCTATAGATC CTTCTGCAAC CACAACGTGT CTCTGATGCT GGAGGCCACC 
CAAACTCCTT CGGAGGAGCC AGAAGTTGAT GCCCATCTGC CTCTGATCCT GGGTCCTGTG 
CTGGCCTTGC CGGTCCTGGT GGCCCTGGGT GCTCTAGGCT TGTGGCGTGT CCGGCGGAGG 
CAGGAGAAGC AGCGGGATTT GCACAGTGAC CTGGGCGAGT CCAGTCTCAT CCTGAAGGCA 
TCTGAACAGG CAGACAGCAT GTTGGGGGAC TTCCTGGACA GCGACTGTAC TACGGGCAGC 
GGCTCGGGGC TCCCCTTCTT GGTGCAGAGG ACGGTAGCTC GGCAGGTTGC GCTGGTAGAG 
TGTGTGGGAA AGGGCCGATA TGGTGAGGTG TGGCGCGGTT CGTGGCATGG CGAGAGTGTG 
GCGGTCAAGA TTTTCTCCTC ACGAGATGAG CAGTCCTGGT TCCGGGAGAC GGAGATCTAC 
AACACAGTTC TGCTTAGACA CGACAACATC CTAGGCTTCA TCGCCTCCGA CATGACTTCG 
CGGAACTCGA GCACGCAGCT GTGGCTCATC ACCCACTACC ATGAACACGG CTCCCTCTAT 
GACTTTCTGC AGAGGCAGAC GCTGGAGCCC CAGTTGGCCC TGAGGCTAGC TGTGTCCGCG 
GCCTGCGGCC TGGCGCACCT ACATGTGGAG ATCTTTGGCA CTCAAGGCAA ACCAGCCATT 
GCCCATCGTG ACCTCAAGAG TCGCAATGTG CTGGTCAAGA GTAACTTGCA GTGTTGCATT 
GCAGACCTGG GACTGGCTGT GATGCACTCA CAAAGCAGCG ATTACCTGGA TATCGGCAAC 
AACCCCCGAG TGGGTACCAA AAGATACATG GCACCCGAGG TGCTGGATGA GCACATCCGC 
ACAGACTGCT TTGAGTCGTA CAAGTGGACA GACATCTGGG CCTTTGGCCT AGTGCTATGG 
GAGATCGCCC GGCGGACCAT CATCAATGGC ATTGTGGAGG ATTACAGGCC ACCTTTCTAT 
GACATGGTAC CCAATGACCC CAGTTTTGAG GACATGAAAA AGGTGGTGTG CGTTGACCAG 
CAGACACCCA CCATCCCTAA CCGGCTGGCT GCAGATCCGG TCCTCTCCGG GCTGGCCCAG 
ATGATGAGAG AGTGCTGGTA CCCCAACCCC TCTGCTCGCC TCACCGCACT GCGCATAAAG 
AAGACATTGC AGAAGCTCAG TCACAATCCA GAGAAGCCCA AAGTGATTCA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264184.1
CDS	251..1804
Translation	MAGNLTTSLLLSPRTMTLGSFRRGLLMLSVAFGLTRGDLAKPSKLVNCTCESPHCKRPFCQGSWCTVVLVREQGRHPQVYRGCGSLNQELCLGRPTEFLNHHCCYRSFCNHNVSLMLEATQTPSEEPEVDAHLPLILGPVLALPVLVALGALGLWRVRRRQEKQRDLHSDLGESSLILKASEQADSMLGDFLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEHIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSHNPEKPKVIH

Target ORF information:

RefSeq Version	NM_001277255.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277255.1

ORF Insert Sequence:

ATGGCAGGAA ATCTCACCAC ATCTCTTCTC CTATCTCCAA GGACCATGAC CTTGGGGAGC 
TTCAGAAGGG GCCTTTTGAT GCTGTCGGTG GCCTTTGGCC TAACCAGGGG AGACTTGGCG 
AAGCCTTCCA AGCTGGTGAA CTGCACTTGT GAGAGCCCAC ACTGCAAGAG ACCATTCTGC 
CAGGGGTCAT GGTGCACAGT GGTGCTGGTT CGGGAGCAGG GCAGGCACCC CCAGGTCTAT 
CGGGGCTGCG GGAGCCTGAA CCAGGAGCTC TGCTTGGGAC GTCCCACAGA GTTTCTGAAC 
CATCACTGCT GCTATAGATC CTTCTGCAAC CACAACGTGT CTCTGATGCT GGAGGCCACC 
CAAACTCCTT CGGAGGAGCC AGAAGTTGAT GCCCATCTGC CTCTGATCCT GGGTCCTGTG 
CTGGCCTTGC CGGTCCTGGT GGCCCTGGGT GCTCTAGGCT TGTGGCGTGT CCGGCGGAGG 
CAGGAGAAGC AGCGGGATTT GCACAGTGAC CTGGGCGAGT CCAGTCTCAT CCTGAAGGCA 
TCTGAACAGG CAGACAGCAT GTTGGGGGAC TTCCTGGACA GCGACTGTAC TACGGGCAGC 
GGCTCGGGGC TCCCCTTCTT GGTGCAGAGG ACGGTAGCTC GGCAGGTTGC GCTGGTAGAG 
TGTGTGGGAA AGGGCCGATA TGGTGAGGTG TGGCGCGGTT CGTGGCATGG CGAGAGTGTG 
GCGGTCAAGA TTTTCTCCTC ACGAGATGAG CAGTCCTGGT TCCGGGAGAC GGAGATCTAC 
AACACAGTTC TGCTTAGACA CGACAACATC CTAGGCTTCA TCGCCTCCGA CATGACTTCG 
CGGAACTCGA GCACGCAGCT GTGGCTCATC ACCCACTACC ATGAACACGG CTCCCTCTAT 
GACTTTCTGC AGAGGCAGAC GCTGGAGCCC CAGTTGGCCC TGAGGCTAGC TGTGTCCGCG 
GCCTGCGGCC TGGCGCACCT ACATGTGGAG ATCTTTGGCA CTCAAGGCAA ACCAGCCATT 
GCCCATCGTG ACCTCAAGAG TCGCAATGTG CTGGTCAAGA GTAACTTGCA GTGTTGCATT 
GCAGACCTGG GACTGGCTGT GATGCACTCA CAAAGCAGCG ATTACCTGGA TATCGGCAAC 
AACCCCCGAG TGGGTACCAA AAGATACATG GCACCCGAGG TGCTGGATGA GCACATCCGC 
ACAGACTGCT TTGAGTCGTA CAAGTGGACA GACATCTGGG CCTTTGGCCT AGTGCTATGG 
GAGATCGCCC GGCGGACCAT CATCAATGGC ATTGTGGAGG ATTACAGGCC ACCTTTCTAT 
GACATGGTAC CCAATGACCC CAGTTTTGAG GACATGAAAA AGGTGGTGTG CGTTGACCAG 
CAGACACCCA CCATCCCTAA CCGGCTGGCT GCAGATCCGG TCCTCTCCGG GCTGGCCCAG 
ATGATGAGAG AGTGCTGGTA CCCCAACCCC TCTGCTCGCC TCACCGCACT GCGCATAAAG 
AAGACATTGC AGAAGCTCAG TCACAATCCA GAGAAGCCCA AAGTGATTCA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acvrl1 ( NM_001277258.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001264187.1 Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu19836
Clone ID Related Accession (Same CDS sequence)	NM_001277258.1 , NM_009612.3 , NM_001277259.1 , NM_001277257.1
Accession Version	NM_001277258.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase receptor R3 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC104834.4, AK160915.1 and AK134712.1. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 4 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC015083.1, AK134712.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCTTGG GGAGCTTCAG AAGGGGCCTT TTGATGCTGT CGGTGGCCTT TGGCCTAACC 
AGGGGAGACT TGGCGAAGCC TTCCAAGCTG GTGAACTGCA CTTGTGAGAG CCCACACTGC 
AAGAGACCAT TCTGCCAGGG GTCATGGTGC ACAGTGGTGC TGGTTCGGGA GCAGGGCAGG 
CACCCCCAGG TCTATCGGGG CTGCGGGAGC CTGAACCAGG AGCTCTGCTT GGGACGTCCC 
ACAGAGTTTC TGAACCATCA CTGCTGCTAT AGATCCTTCT GCAACCACAA CGTGTCTCTG 
ATGCTGGAGG CCACCCAAAC TCCTTCGGAG GAGCCAGAAG TTGATGCCCA TCTGCCTCTG 
ATCCTGGGTC CTGTGCTGGC CTTGCCGGTC CTGGTGGCCC TGGGTGCTCT AGGCTTGTGG 
CGTGTCCGGC GGAGGCAGGA GAAGCAGCGG GATTTGCACA GTGACCTGGG CGAGTCCAGT 
CTCATCCTGA AGGCATCTGA ACAGGCAGAC AGCATGTTGG GGGACTTCCT GGACAGCGAC 
TGTACTACGG GCAGCGGCTC GGGGCTCCCC TTCTTGGTGC AGAGGACGGT AGCTCGGCAG 
GTTGCGCTGG TAGAGTGTGT GGGAAAGGGC CGATATGGTG AGGTGTGGCG CGGTTCGTGG 
CATGGCGAGA GTGTGGCGGT CAAGATTTTC TCCTCACGAG ATGAGCAGTC CTGGTTCCGG 
GAGACGGAGA TCTACAACAC AGTTCTGCTT AGACACGACA ACATCCTAGG CTTCATCGCC 
TCCGACATGA CTTCGCGGAA CTCGAGCACG CAGCTGTGGC TCATCACCCA CTACCATGAA 
CACGGCTCCC TCTATGACTT TCTGCAGAGG CAGACGCTGG AGCCCCAGTT GGCCCTGAGG 
CTAGCTGTGT CCGCGGCCTG CGGCCTGGCG CACCTACATG TGGAGATCTT TGGCACTCAA 
GGCAAACCAG CCATTGCCCA TCGTGACCTC AAGAGTCGCA ATGTGCTGGT CAAGAGTAAC 
TTGCAGTGTT GCATTGCAGA CCTGGGACTG GCTGTGATGC ACTCACAAAG CAGCGATTAC 
CTGGATATCG GCAACAACCC CCGAGTGGGT ACCAAAAGAT ACATGGCACC CGAGGTGCTG 
GATGAGCACA TCCGCACAGA CTGCTTTGAG TCGTACAAGT GGACAGACAT CTGGGCCTTT 
GGCCTAGTGC TATGGGAGAT CGCCCGGCGG ACCATCATCA ATGGCATTGT GGAGGATTAC 
AGGCCACCTT TCTATGACAT GGTACCCAAT GACCCCAGTT TTGAGGACAT GAAAAAGGTG 
GTGTGCGTTG ACCAGCAGAC ACCCACCATC CCTAACCGGC TGGCTGCAGA TCCGGTCCTC 
TCCGGGCTGG CCCAGATGAT GAGAGAGTGC TGGTACCCCA ACCCCTCTGC TCGCCTCACC 
GCACTGCGCA TAAAGAAGAC ATTGCAGAAG CTCAGTCACA ATCCAGAGAA GCCCAAAGTG 
ATTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264187.1
CDS	204..1712
Translation	MTLGSFRRGLLMLSVAFGLTRGDLAKPSKLVNCTCESPHCKRPFCQGSWCTVVLVREQGRHPQVYRGCGSLNQELCLGRPTEFLNHHCCYRSFCNHNVSLMLEATQTPSEEPEVDAHLPLILGPVLALPVLVALGALGLWRVRRRQEKQRDLHSDLGESSLILKASEQADSMLGDFLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEHIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSHNPEKPKVIH

Target ORF information:

RefSeq Version	NM_001277258.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277258.1

ORF Insert Sequence:

ATGACCTTGG GGAGCTTCAG AAGGGGCCTT TTGATGCTGT CGGTGGCCTT TGGCCTAACC 
AGGGGAGACT TGGCGAAGCC TTCCAAGCTG GTGAACTGCA CTTGTGAGAG CCCACACTGC 
AAGAGACCAT TCTGCCAGGG GTCATGGTGC ACAGTGGTGC TGGTTCGGGA GCAGGGCAGG 
CACCCCCAGG TCTATCGGGG CTGCGGGAGC CTGAACCAGG AGCTCTGCTT GGGACGTCCC 
ACAGAGTTTC TGAACCATCA CTGCTGCTAT AGATCCTTCT GCAACCACAA CGTGTCTCTG 
ATGCTGGAGG CCACCCAAAC TCCTTCGGAG GAGCCAGAAG TTGATGCCCA TCTGCCTCTG 
ATCCTGGGTC CTGTGCTGGC CTTGCCGGTC CTGGTGGCCC TGGGTGCTCT AGGCTTGTGG 
CGTGTCCGGC GGAGGCAGGA GAAGCAGCGG GATTTGCACA GTGACCTGGG CGAGTCCAGT 
CTCATCCTGA AGGCATCTGA ACAGGCAGAC AGCATGTTGG GGGACTTCCT GGACAGCGAC 
TGTACTACGG GCAGCGGCTC GGGGCTCCCC TTCTTGGTGC AGAGGACGGT AGCTCGGCAG 
GTTGCGCTGG TAGAGTGTGT GGGAAAGGGC CGATATGGTG AGGTGTGGCG CGGTTCGTGG 
CATGGCGAGA GTGTGGCGGT CAAGATTTTC TCCTCACGAG ATGAGCAGTC CTGGTTCCGG 
GAGACGGAGA TCTACAACAC AGTTCTGCTT AGACACGACA ACATCCTAGG CTTCATCGCC 
TCCGACATGA CTTCGCGGAA CTCGAGCACG CAGCTGTGGC TCATCACCCA CTACCATGAA 
CACGGCTCCC TCTATGACTT TCTGCAGAGG CAGACGCTGG AGCCCCAGTT GGCCCTGAGG 
CTAGCTGTGT CCGCGGCCTG CGGCCTGGCG CACCTACATG TGGAGATCTT TGGCACTCAA 
GGCAAACCAG CCATTGCCCA TCGTGACCTC AAGAGTCGCA ATGTGCTGGT CAAGAGTAAC 
TTGCAGTGTT GCATTGCAGA CCTGGGACTG GCTGTGATGC ACTCACAAAG CAGCGATTAC 
CTGGATATCG GCAACAACCC CCGAGTGGGT ACCAAAAGAT ACATGGCACC CGAGGTGCTG 
GATGAGCACA TCCGCACAGA CTGCTTTGAG TCGTACAAGT GGACAGACAT CTGGGCCTTT 
GGCCTAGTGC TATGGGAGAT CGCCCGGCGG ACCATCATCA ATGGCATTGT GGAGGATTAC 
AGGCCACCTT TCTATGACAT GGTACCCAAT GACCCCAGTT TTGAGGACAT GAAAAAGGTG 
GTGTGCGTTG ACCAGCAGAC ACCCACCATC CCTAACCGGC TGGCTGCAGA TCCGGTCCTC 
TCCGGGCTGG CCCAGATGAT GAGAGAGTGC TGGTACCCCA ACCCCTCTGC TCGCCTCACC 
GCACTGCGCA TAAAGAAGAC ATTGCAGAAG CTCAGTCACA ATCCAGAGAA GCCCAAAGTG 
ATTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acvrl1 ( NM_009612.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033742.2 Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19836
Clone ID Related Accession (Same CDS sequence)	NM_001277258.1 , NM_009612.3 , NM_001277259.1 , NM_001277257.1
Accession Version	NM_009612.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase receptor R3 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC104834.4, BB869983.1 and AK134712.1. On Mar 26, 2013 this sequence version replaced NM_009612.2. Transcript Variant: This variant (1) encodes the predominant isoform (a). Variants 1, 2, 3, and 4 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L48015.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCTTGG GGAGCTTCAG AAGGGGCCTT TTGATGCTGT CGGTGGCCTT TGGCCTAACC 
AGGGGAGACT TGGCGAAGCC TTCCAAGCTG GTGAACTGCA CTTGTGAGAG CCCACACTGC 
AAGAGACCAT TCTGCCAGGG GTCATGGTGC ACAGTGGTGC TGGTTCGGGA GCAGGGCAGG 
CACCCCCAGG TCTATCGGGG CTGCGGGAGC CTGAACCAGG AGCTCTGCTT GGGACGTCCC 
ACAGAGTTTC TGAACCATCA CTGCTGCTAT AGATCCTTCT GCAACCACAA CGTGTCTCTG 
ATGCTGGAGG CCACCCAAAC TCCTTCGGAG GAGCCAGAAG TTGATGCCCA TCTGCCTCTG 
ATCCTGGGTC CTGTGCTGGC CTTGCCGGTC CTGGTGGCCC TGGGTGCTCT AGGCTTGTGG 
CGTGTCCGGC GGAGGCAGGA GAAGCAGCGG GATTTGCACA GTGACCTGGG CGAGTCCAGT 
CTCATCCTGA AGGCATCTGA ACAGGCAGAC AGCATGTTGG GGGACTTCCT GGACAGCGAC 
TGTACTACGG GCAGCGGCTC GGGGCTCCCC TTCTTGGTGC AGAGGACGGT AGCTCGGCAG 
GTTGCGCTGG TAGAGTGTGT GGGAAAGGGC CGATATGGTG AGGTGTGGCG CGGTTCGTGG 
CATGGCGAGA GTGTGGCGGT CAAGATTTTC TCCTCACGAG ATGAGCAGTC CTGGTTCCGG 
GAGACGGAGA TCTACAACAC AGTTCTGCTT AGACACGACA ACATCCTAGG CTTCATCGCC 
TCCGACATGA CTTCGCGGAA CTCGAGCACG CAGCTGTGGC TCATCACCCA CTACCATGAA 
CACGGCTCCC TCTATGACTT TCTGCAGAGG CAGACGCTGG AGCCCCAGTT GGCCCTGAGG 
CTAGCTGTGT CCGCGGCCTG CGGCCTGGCG CACCTACATG TGGAGATCTT TGGCACTCAA 
GGCAAACCAG CCATTGCCCA TCGTGACCTC AAGAGTCGCA ATGTGCTGGT CAAGAGTAAC 
TTGCAGTGTT GCATTGCAGA CCTGGGACTG GCTGTGATGC ACTCACAAAG CAGCGATTAC 
CTGGATATCG GCAACAACCC CCGAGTGGGT ACCAAAAGAT ACATGGCACC CGAGGTGCTG 
GATGAGCACA TCCGCACAGA CTGCTTTGAG TCGTACAAGT GGACAGACAT CTGGGCCTTT 
GGCCTAGTGC TATGGGAGAT CGCCCGGCGG ACCATCATCA ATGGCATTGT GGAGGATTAC 
AGGCCACCTT TCTATGACAT GGTACCCAAT GACCCCAGTT TTGAGGACAT GAAAAAGGTG 
GTGTGCGTTG ACCAGCAGAC ACCCACCATC CCTAACCGGC TGGCTGCAGA TCCGGTCCTC 
TCCGGGCTGG CCCAGATGAT GAGAGAGTGC TGGTACCCCA ACCCCTCTGC TCGCCTCACC 
GCACTGCGCA TAAAGAAGAC ATTGCAGAAG CTCAGTCACA ATCCAGAGAA GCCCAAAGTG 
ATTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033742.2
CDS	273..1781
Translation	MTLGSFRRGLLMLSVAFGLTRGDLAKPSKLVNCTCESPHCKRPFCQGSWCTVVLVREQGRHPQVYRGCGSLNQELCLGRPTEFLNHHCCYRSFCNHNVSLMLEATQTPSEEPEVDAHLPLILGPVLALPVLVALGALGLWRVRRRQEKQRDLHSDLGESSLILKASEQADSMLGDFLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEHIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSHNPEKPKVIH

Target ORF information:

RefSeq Version	NM_009612.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009612.3

ORF Insert Sequence:

ATGACCTTGG GGAGCTTCAG AAGGGGCCTT TTGATGCTGT CGGTGGCCTT TGGCCTAACC 
AGGGGAGACT TGGCGAAGCC TTCCAAGCTG GTGAACTGCA CTTGTGAGAG CCCACACTGC 
AAGAGACCAT TCTGCCAGGG GTCATGGTGC ACAGTGGTGC TGGTTCGGGA GCAGGGCAGG 
CACCCCCAGG TCTATCGGGG CTGCGGGAGC CTGAACCAGG AGCTCTGCTT GGGACGTCCC 
ACAGAGTTTC TGAACCATCA CTGCTGCTAT AGATCCTTCT GCAACCACAA CGTGTCTCTG 
ATGCTGGAGG CCACCCAAAC TCCTTCGGAG GAGCCAGAAG TTGATGCCCA TCTGCCTCTG 
ATCCTGGGTC CTGTGCTGGC CTTGCCGGTC CTGGTGGCCC TGGGTGCTCT AGGCTTGTGG 
CGTGTCCGGC GGAGGCAGGA GAAGCAGCGG GATTTGCACA GTGACCTGGG CGAGTCCAGT 
CTCATCCTGA AGGCATCTGA ACAGGCAGAC AGCATGTTGG GGGACTTCCT GGACAGCGAC 
TGTACTACGG GCAGCGGCTC GGGGCTCCCC TTCTTGGTGC AGAGGACGGT AGCTCGGCAG 
GTTGCGCTGG TAGAGTGTGT GGGAAAGGGC CGATATGGTG AGGTGTGGCG CGGTTCGTGG 
CATGGCGAGA GTGTGGCGGT CAAGATTTTC TCCTCACGAG ATGAGCAGTC CTGGTTCCGG 
GAGACGGAGA TCTACAACAC AGTTCTGCTT AGACACGACA ACATCCTAGG CTTCATCGCC 
TCCGACATGA CTTCGCGGAA CTCGAGCACG CAGCTGTGGC TCATCACCCA CTACCATGAA 
CACGGCTCCC TCTATGACTT TCTGCAGAGG CAGACGCTGG AGCCCCAGTT GGCCCTGAGG 
CTAGCTGTGT CCGCGGCCTG CGGCCTGGCG CACCTACATG TGGAGATCTT TGGCACTCAA 
GGCAAACCAG CCATTGCCCA TCGTGACCTC AAGAGTCGCA ATGTGCTGGT CAAGAGTAAC 
TTGCAGTGTT GCATTGCAGA CCTGGGACTG GCTGTGATGC ACTCACAAAG CAGCGATTAC 
CTGGATATCG GCAACAACCC CCGAGTGGGT ACCAAAAGAT ACATGGCACC CGAGGTGCTG 
GATGAGCACA TCCGCACAGA CTGCTTTGAG TCGTACAAGT GGACAGACAT CTGGGCCTTT 
GGCCTAGTGC TATGGGAGAT CGCCCGGCGG ACCATCATCA ATGGCATTGT GGAGGATTAC 
AGGCCACCTT TCTATGACAT GGTACCCAAT GACCCCAGTT TTGAGGACAT GAAAAAGGTG 
GTGTGCGTTG ACCAGCAGAC ACCCACCATC CCTAACCGGC TGGCTGCAGA TCCGGTCCTC 
TCCGGGCTGG CCCAGATGAT GAGAGAGTGC TGGTACCCCA ACCCCTCTGC TCGCCTCACC 
GCACTGCGCA TAAAGAAGAC ATTGCAGAAG CTCAGTCACA ATCCAGAGAA GCCCAAAGTG 
ATTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acvrl1 ( NM_001277259.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001264188.1 Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 2, mRNA.

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CloneID	OMu19836
Clone ID Related Accession (Same CDS sequence)	NM_001277258.1 , NM_009612.3 , NM_001277259.1 , NM_001277257.1
Accession Version	NM_001277259.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase receptor R3 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC104834.4, AK160915.1 and AK134712.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 4 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK160915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCTTGG GGAGCTTCAG AAGGGGCCTT TTGATGCTGT CGGTGGCCTT TGGCCTAACC 
AGGGGAGACT TGGCGAAGCC TTCCAAGCTG GTGAACTGCA CTTGTGAGAG CCCACACTGC 
AAGAGACCAT TCTGCCAGGG GTCATGGTGC ACAGTGGTGC TGGTTCGGGA GCAGGGCAGG 
CACCCCCAGG TCTATCGGGG CTGCGGGAGC CTGAACCAGG AGCTCTGCTT GGGACGTCCC 
ACAGAGTTTC TGAACCATCA CTGCTGCTAT AGATCCTTCT GCAACCACAA CGTGTCTCTG 
ATGCTGGAGG CCACCCAAAC TCCTTCGGAG GAGCCAGAAG TTGATGCCCA TCTGCCTCTG 
ATCCTGGGTC CTGTGCTGGC CTTGCCGGTC CTGGTGGCCC TGGGTGCTCT AGGCTTGTGG 
CGTGTCCGGC GGAGGCAGGA GAAGCAGCGG GATTTGCACA GTGACCTGGG CGAGTCCAGT 
CTCATCCTGA AGGCATCTGA ACAGGCAGAC AGCATGTTGG GGGACTTCCT GGACAGCGAC 
TGTACTACGG GCAGCGGCTC GGGGCTCCCC TTCTTGGTGC AGAGGACGGT AGCTCGGCAG 
GTTGCGCTGG TAGAGTGTGT GGGAAAGGGC CGATATGGTG AGGTGTGGCG CGGTTCGTGG 
CATGGCGAGA GTGTGGCGGT CAAGATTTTC TCCTCACGAG ATGAGCAGTC CTGGTTCCGG 
GAGACGGAGA TCTACAACAC AGTTCTGCTT AGACACGACA ACATCCTAGG CTTCATCGCC 
TCCGACATGA CTTCGCGGAA CTCGAGCACG CAGCTGTGGC TCATCACCCA CTACCATGAA 
CACGGCTCCC TCTATGACTT TCTGCAGAGG CAGACGCTGG AGCCCCAGTT GGCCCTGAGG 
CTAGCTGTGT CCGCGGCCTG CGGCCTGGCG CACCTACATG TGGAGATCTT TGGCACTCAA 
GGCAAACCAG CCATTGCCCA TCGTGACCTC AAGAGTCGCA ATGTGCTGGT CAAGAGTAAC 
TTGCAGTGTT GCATTGCAGA CCTGGGACTG GCTGTGATGC ACTCACAAAG CAGCGATTAC 
CTGGATATCG GCAACAACCC CCGAGTGGGT ACCAAAAGAT ACATGGCACC CGAGGTGCTG 
GATGAGCACA TCCGCACAGA CTGCTTTGAG TCGTACAAGT GGACAGACAT CTGGGCCTTT 
GGCCTAGTGC TATGGGAGAT CGCCCGGCGG ACCATCATCA ATGGCATTGT GGAGGATTAC 
AGGCCACCTT TCTATGACAT GGTACCCAAT GACCCCAGTT TTGAGGACAT GAAAAAGGTG 
GTGTGCGTTG ACCAGCAGAC ACCCACCATC CCTAACCGGC TGGCTGCAGA TCCGGTCCTC 
TCCGGGCTGG CCCAGATGAT GAGAGAGTGC TGGTACCCCA ACCCCTCTGC TCGCCTCACC 
GCACTGCGCA TAAAGAAGAC ATTGCAGAAG CTCAGTCACA ATCCAGAGAA GCCCAAAGTG 
ATTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264188.1
CDS	291..1799
Translation	MTLGSFRRGLLMLSVAFGLTRGDLAKPSKLVNCTCESPHCKRPFCQGSWCTVVLVREQGRHPQVYRGCGSLNQELCLGRPTEFLNHHCCYRSFCNHNVSLMLEATQTPSEEPEVDAHLPLILGPVLALPVLVALGALGLWRVRRRQEKQRDLHSDLGESSLILKASEQADSMLGDFLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEHIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSHNPEKPKVIH

Target ORF information:

RefSeq Version	NM_001277259.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277259.1

ORF Insert Sequence:

ATGACCTTGG GGAGCTTCAG AAGGGGCCTT TTGATGCTGT CGGTGGCCTT TGGCCTAACC 
AGGGGAGACT TGGCGAAGCC TTCCAAGCTG GTGAACTGCA CTTGTGAGAG CCCACACTGC 
AAGAGACCAT TCTGCCAGGG GTCATGGTGC ACAGTGGTGC TGGTTCGGGA GCAGGGCAGG 
CACCCCCAGG TCTATCGGGG CTGCGGGAGC CTGAACCAGG AGCTCTGCTT GGGACGTCCC 
ACAGAGTTTC TGAACCATCA CTGCTGCTAT AGATCCTTCT GCAACCACAA CGTGTCTCTG 
ATGCTGGAGG CCACCCAAAC TCCTTCGGAG GAGCCAGAAG TTGATGCCCA TCTGCCTCTG 
ATCCTGGGTC CTGTGCTGGC CTTGCCGGTC CTGGTGGCCC TGGGTGCTCT AGGCTTGTGG 
CGTGTCCGGC GGAGGCAGGA GAAGCAGCGG GATTTGCACA GTGACCTGGG CGAGTCCAGT 
CTCATCCTGA AGGCATCTGA ACAGGCAGAC AGCATGTTGG GGGACTTCCT GGACAGCGAC 
TGTACTACGG GCAGCGGCTC GGGGCTCCCC TTCTTGGTGC AGAGGACGGT AGCTCGGCAG 
GTTGCGCTGG TAGAGTGTGT GGGAAAGGGC CGATATGGTG AGGTGTGGCG CGGTTCGTGG 
CATGGCGAGA GTGTGGCGGT CAAGATTTTC TCCTCACGAG ATGAGCAGTC CTGGTTCCGG 
GAGACGGAGA TCTACAACAC AGTTCTGCTT AGACACGACA ACATCCTAGG CTTCATCGCC 
TCCGACATGA CTTCGCGGAA CTCGAGCACG CAGCTGTGGC TCATCACCCA CTACCATGAA 
CACGGCTCCC TCTATGACTT TCTGCAGAGG CAGACGCTGG AGCCCCAGTT GGCCCTGAGG 
CTAGCTGTGT CCGCGGCCTG CGGCCTGGCG CACCTACATG TGGAGATCTT TGGCACTCAA 
GGCAAACCAG CCATTGCCCA TCGTGACCTC AAGAGTCGCA ATGTGCTGGT CAAGAGTAAC 
TTGCAGTGTT GCATTGCAGA CCTGGGACTG GCTGTGATGC ACTCACAAAG CAGCGATTAC 
CTGGATATCG GCAACAACCC CCGAGTGGGT ACCAAAAGAT ACATGGCACC CGAGGTGCTG 
GATGAGCACA TCCGCACAGA CTGCTTTGAG TCGTACAAGT GGACAGACAT CTGGGCCTTT 
GGCCTAGTGC TATGGGAGAT CGCCCGGCGG ACCATCATCA ATGGCATTGT GGAGGATTAC 
AGGCCACCTT TCTATGACAT GGTACCCAAT GACCCCAGTT TTGAGGACAT GAAAAAGGTG 
GTGTGCGTTG ACCAGCAGAC ACCCACCATC CCTAACCGGC TGGCTGCAGA TCCGGTCCTC 
TCCGGGCTGG CCCAGATGAT GAGAGAGTGC TGGTACCCCA ACCCCTCTGC TCGCCTCACC 
GCACTGCGCA TAAAGAAGAC ATTGCAGAAG CTCAGTCACA ATCCAGAGAA GCCCAAAGTG 
ATTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acvrl1 ( NM_001277257.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001264186.1 Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 3, mRNA.

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CloneID	OMu19836
Clone ID Related Accession (Same CDS sequence)	NM_001277258.1 , NM_009612.3 , NM_001277259.1 , NM_001277257.1
Accession Version	NM_001277257.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase receptor R3 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC104834.4, BB869400.1 and AK134712.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 4 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC014291.1, AK134712.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCTTGG GGAGCTTCAG AAGGGGCCTT TTGATGCTGT CGGTGGCCTT TGGCCTAACC 
AGGGGAGACT TGGCGAAGCC TTCCAAGCTG GTGAACTGCA CTTGTGAGAG CCCACACTGC 
AAGAGACCAT TCTGCCAGGG GTCATGGTGC ACAGTGGTGC TGGTTCGGGA GCAGGGCAGG 
CACCCCCAGG TCTATCGGGG CTGCGGGAGC CTGAACCAGG AGCTCTGCTT GGGACGTCCC 
ACAGAGTTTC TGAACCATCA CTGCTGCTAT AGATCCTTCT GCAACCACAA CGTGTCTCTG 
ATGCTGGAGG CCACCCAAAC TCCTTCGGAG GAGCCAGAAG TTGATGCCCA TCTGCCTCTG 
ATCCTGGGTC CTGTGCTGGC CTTGCCGGTC CTGGTGGCCC TGGGTGCTCT AGGCTTGTGG 
CGTGTCCGGC GGAGGCAGGA GAAGCAGCGG GATTTGCACA GTGACCTGGG CGAGTCCAGT 
CTCATCCTGA AGGCATCTGA ACAGGCAGAC AGCATGTTGG GGGACTTCCT GGACAGCGAC 
TGTACTACGG GCAGCGGCTC GGGGCTCCCC TTCTTGGTGC AGAGGACGGT AGCTCGGCAG 
GTTGCGCTGG TAGAGTGTGT GGGAAAGGGC CGATATGGTG AGGTGTGGCG CGGTTCGTGG 
CATGGCGAGA GTGTGGCGGT CAAGATTTTC TCCTCACGAG ATGAGCAGTC CTGGTTCCGG 
GAGACGGAGA TCTACAACAC AGTTCTGCTT AGACACGACA ACATCCTAGG CTTCATCGCC 
TCCGACATGA CTTCGCGGAA CTCGAGCACG CAGCTGTGGC TCATCACCCA CTACCATGAA 
CACGGCTCCC TCTATGACTT TCTGCAGAGG CAGACGCTGG AGCCCCAGTT GGCCCTGAGG 
CTAGCTGTGT CCGCGGCCTG CGGCCTGGCG CACCTACATG TGGAGATCTT TGGCACTCAA 
GGCAAACCAG CCATTGCCCA TCGTGACCTC AAGAGTCGCA ATGTGCTGGT CAAGAGTAAC 
TTGCAGTGTT GCATTGCAGA CCTGGGACTG GCTGTGATGC ACTCACAAAG CAGCGATTAC 
CTGGATATCG GCAACAACCC CCGAGTGGGT ACCAAAAGAT ACATGGCACC CGAGGTGCTG 
GATGAGCACA TCCGCACAGA CTGCTTTGAG TCGTACAAGT GGACAGACAT CTGGGCCTTT 
GGCCTAGTGC TATGGGAGAT CGCCCGGCGG ACCATCATCA ATGGCATTGT GGAGGATTAC 
AGGCCACCTT TCTATGACAT GGTACCCAAT GACCCCAGTT TTGAGGACAT GAAAAAGGTG 
GTGTGCGTTG ACCAGCAGAC ACCCACCATC CCTAACCGGC TGGCTGCAGA TCCGGTCCTC 
TCCGGGCTGG CCCAGATGAT GAGAGAGTGC TGGTACCCCA ACCCCTCTGC TCGCCTCACC 
GCACTGCGCA TAAAGAAGAC ATTGCAGAAG CTCAGTCACA ATCCAGAGAA GCCCAAAGTG 
ATTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264186.1
CDS	235..1743
Translation	MTLGSFRRGLLMLSVAFGLTRGDLAKPSKLVNCTCESPHCKRPFCQGSWCTVVLVREQGRHPQVYRGCGSLNQELCLGRPTEFLNHHCCYRSFCNHNVSLMLEATQTPSEEPEVDAHLPLILGPVLALPVLVALGALGLWRVRRRQEKQRDLHSDLGESSLILKASEQADSMLGDFLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEHIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSHNPEKPKVIH

Target ORF information:

RefSeq Version	NM_001277257.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus activin A receptor, type II-like 1 (Acvrl1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277257.1

ORF Insert Sequence:

ATGACCTTGG GGAGCTTCAG AAGGGGCCTT TTGATGCTGT CGGTGGCCTT TGGCCTAACC 
AGGGGAGACT TGGCGAAGCC TTCCAAGCTG GTGAACTGCA CTTGTGAGAG CCCACACTGC 
AAGAGACCAT TCTGCCAGGG GTCATGGTGC ACAGTGGTGC TGGTTCGGGA GCAGGGCAGG 
CACCCCCAGG TCTATCGGGG CTGCGGGAGC CTGAACCAGG AGCTCTGCTT GGGACGTCCC 
ACAGAGTTTC TGAACCATCA CTGCTGCTAT AGATCCTTCT GCAACCACAA CGTGTCTCTG 
ATGCTGGAGG CCACCCAAAC TCCTTCGGAG GAGCCAGAAG TTGATGCCCA TCTGCCTCTG 
ATCCTGGGTC CTGTGCTGGC CTTGCCGGTC CTGGTGGCCC TGGGTGCTCT AGGCTTGTGG 
CGTGTCCGGC GGAGGCAGGA GAAGCAGCGG GATTTGCACA GTGACCTGGG CGAGTCCAGT 
CTCATCCTGA AGGCATCTGA ACAGGCAGAC AGCATGTTGG GGGACTTCCT GGACAGCGAC 
TGTACTACGG GCAGCGGCTC GGGGCTCCCC TTCTTGGTGC AGAGGACGGT AGCTCGGCAG 
GTTGCGCTGG TAGAGTGTGT GGGAAAGGGC CGATATGGTG AGGTGTGGCG CGGTTCGTGG 
CATGGCGAGA GTGTGGCGGT CAAGATTTTC TCCTCACGAG ATGAGCAGTC CTGGTTCCGG 
GAGACGGAGA TCTACAACAC AGTTCTGCTT AGACACGACA ACATCCTAGG CTTCATCGCC 
TCCGACATGA CTTCGCGGAA CTCGAGCACG CAGCTGTGGC TCATCACCCA CTACCATGAA 
CACGGCTCCC TCTATGACTT TCTGCAGAGG CAGACGCTGG AGCCCCAGTT GGCCCTGAGG 
CTAGCTGTGT CCGCGGCCTG CGGCCTGGCG CACCTACATG TGGAGATCTT TGGCACTCAA 
GGCAAACCAG CCATTGCCCA TCGTGACCTC AAGAGTCGCA ATGTGCTGGT CAAGAGTAAC 
TTGCAGTGTT GCATTGCAGA CCTGGGACTG GCTGTGATGC ACTCACAAAG CAGCGATTAC 
CTGGATATCG GCAACAACCC CCGAGTGGGT ACCAAAAGAT ACATGGCACC CGAGGTGCTG 
GATGAGCACA TCCGCACAGA CTGCTTTGAG TCGTACAAGT GGACAGACAT CTGGGCCTTT 
GGCCTAGTGC TATGGGAGAT CGCCCGGCGG ACCATCATCA ATGGCATTGT GGAGGATTAC 
AGGCCACCTT TCTATGACAT GGTACCCAAT GACCCCAGTT TTGAGGACAT GAAAAAGGTG 
GTGTGCGTTG ACCAGCAGAC ACCCACCATC CCTAACCGGC TGGCTGCAGA TCCGGTCCTC 
TCCGGGCTGG CCCAGATGAT GAGAGAGTGC TGGTACCCCA ACCCCTCTGC TCGCCTCACC 
GCACTGCGCA TAAAGAAGAC ATTGCAGAAG CTCAGTCACA ATCCAGAGAA GCCCAAAGTG 
ATTCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The TGF? pathway is a key player for the endothelial-to-hematopoietic transition in the embryonic aorta.
Developmental biology(2017 Dec)
Lempereur A,Canto PY,Richard C,Martin S,Thalgott J,Raymond K,Lebrin F,Drevon C,Jaffredo T

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Acvrl1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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