Prss28 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prss28
Entrez Gene ID	114661
Full Name	protease, serine 28
Synonyms	Isp1,mIsp-1
General protein information	Preferred Names protease, serine 28 Names serine protease 28 ISP-1 implantation serine protease 1 implantation serine proteinase 1 strypsin tryptase-like proteinase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 A3.3\|17 12.53 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_053259.2	NP_444489.2	serine protease 28 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Prss28	NP_444489.2
Rattus norvegicus (Norway rat)	LOC685321	XP_003750843.1
	LOC722416	XP_001118566.2

Gene Ontology
Bibliography

Related articles in PubMed

Thyroid hormone regulates protease expression and activation of Notch signaling in implantation and embryo development.
Piccirilli D, Baldini E, Massimiani M, Camaioni A, Salustri A, Bernardini R, Centanni M, Ulisse S, Moretti C, Campagnolo L
The Journal of endocrinology236(1)1-12(2018 Jan)

Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis.
Khalif? M, Young R, Passet B, Halliez S, Vilotte M, Jaffrezic F, Marthey S, B?ringue V, Vaiman D, Le Provost F, Laude H, Vilotte JL
PloS one6(8)e23253(2011)

Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors.
Sharma N, Kumar R, Renaux B, Saifeddine M, Nishikawa S, Mihara K, Ramachandran R, Hollenberg MD, Rancourt DE
PloS one6(11)e27888(2011)

Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation.
Sharma N, Liu S, Tang L, Irwin J, Meng G, Rancourt DE
BMC developmental biology661(2006 Dec)

Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty.
Vesper AH, Raetzman LT, Camper SA
Endocrinology147(4)1654-63(2006 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Hypothyroidism induces a significant reduction of proteases Isp1 and Isp2 gene expressions and Notch signaling.
Title: Thyroid hormone regulates protease expression and activation of Notch signaling in implantation and embryo development.

ISP1 might signal to cells by cleaving and activating proteinase-activated receptors (PARs) and therefore assessed PARs 1, 2 and 4 as potential ISP1 targets.
Title: Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors.

ISP1 plays a critical role in embryo hatching and implantation
Title: Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation.

organization, structure and postulated function of the implantation serine proteinase (ISP1 and 2) genes.
Title: Murine implantation serine proteinases 1 and 2: structure, function and evolution.

the ISP1 and ISP2 genes are co-expressed within the endometrial gland
Title: Embryonic hatching enzyme strypsin/ISP1 is expressed with ISP2 in endometrial glands during implantation.

The following Prss28 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prss28 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58403	NM_053259.2 Latest version!	Mus musculus protease, serine 28 (Prss28), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prss28 ( NM_053259.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_444489.2 Mus musculus protease, serine 28 (Prss28), mRNA.

Price & Availability↑

CloneID	OMu58403
Clone ID Related Accession (Same CDS sequence)	NM_053259.2
Accession Version	NM_053259.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	serine protease 28 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK144498.1 and AC122454.4. On Sep 22, 2006 this sequence version replaced NM_053259.1. ##Evidence-Data-START## Transcript exon combination :: AK144498.1 [ECO:0000332] ##Evidence-Data-END##

ATGTTCAGAC TGTTGCTCCT GGCTCTCTCC TGTCTGGAAA GTACCGTGTT CATGGCCTCT 
GTATCTATCT CCAGAAGCAA GCCAGTGGGC ATTGTGGGGG GTCAATGTAC CCCACCAGGG 
AAGTGGCCAT GGCAGGTCAG CCTAAGAATG TACAGTTACG AGGTGAACTC CTGGGTGCAC 
ATCTGTGGGG GCTCCATCAT CCACCCTCAG TGGATTCTGA CTGCTGCTCA CTGCATCCAA 
AGTCAGGACG CCGACCCAGC CGTATACCGG GTCCAGGTGG GGGAAGTATA CCTCTATAAG 
GAGCAGGAAC TTCTGAACAT CAGCAGGATC ATCATCCACC CTGACTACAA CGATGTTAGT 
AAGAGGTTTG ACTTGGCCCT GATGCAGTTG ACTGCCCTCC TGGTCACATC CACAAATGTC 
AGTCCAGTCT CTCTGCCAAA AGACAGCTCA ACCTTCGACT CCACTGACCA GTGTTGGCTG 
GTTGGCTGGG GCAACCTTCT CCAACGTGTG CCTCTGCAGC CTCCCTATCA ACTGCATGAG 
GTGAAGATCC CAATTCAGGA CAACAAGAGC TGTAAGCGGG CTTATAGGAA GAAGTCATCC 
GACGAGCACA AAGCTGTGGC CATCTTTGAC GACATGCTTT GTGCTGGCAC CTCAGGCCGA 
GGCCCCTGTT TTGGTGACTC TGGGGGTCCC TTGGTCTGCT GGAAGAGCAA CAAGTGGATA 
CAGGTGGGCG TGGTCAGCAA GGGGATCGAT TGCAGCAACA ATCTGCCATC AATCTTCTCA 
AGAGTCCAGA GCTCCTTAGC CTGGATCCAT CAACACATCC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444489.2
CDS	162..986
Translation	MFRLLLLALSCLESTVFMASVSISRSKPVGIVGGQCTPPGKWPWQVSLRMYSYEVNSWVHICGGSIIHPQWILTAAHCIQSQDADPAVYRVQVGEVYLYKEQELLNISRIIIHPDYNDVSKRFDLALMQLTALLVTSTNVSPVSLPKDSSTFDSTDQCWLVGWGNLLQRVPLQPPYQLHEVKIPIQDNKSCKRAYRKKSSDEHKAVAIFDDMLCAGTSGRGPCFGDSGGPLVCWKSNKWIQVGVVSKGIDCSNNLPSIFSRVQSSLAWIHQHIQ

Target ORF information:

RefSeq Version	NM_053259.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protease, serine 28 (Prss28), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053259.2

ORF Insert Sequence:

ATGTTCAGAC TGTTGCTCCT GGCTCTCTCC TGTCTGGAAA GTACCGTGTT CATGGCCTCT 
GTATCTATCT CCAGAAGCAA GCCAGTGGGC ATTGTGGGGG GTCAATGTAC CCCACCAGGG 
AAGTGGCCAT GGCAGGTCAG CCTAAGAATG TACAGTTACG AGGTGAACTC CTGGGTGCAC 
ATCTGTGGGG GCTCCATCAT CCACCCTCAG TGGATTCTGA CTGCTGCTCA CTGCATCCAA 
AGTCAGGACG CCGACCCAGC CGTATACCGG GTCCAGGTGG GGGAAGTATA CCTCTATAAG 
GAGCAGGAAC TTCTGAACAT CAGCAGGATC ATCATCCACC CTGACTACAA CGATGTTAGT 
AAGAGGTTTG ACTTGGCCCT GATGCAGTTG ACTGCCCTCC TGGTCACATC CACAAATGTC 
AGTCCAGTCT CTCTGCCAAA AGACAGCTCA ACCTTCGACT CCACTGACCA GTGTTGGCTG 
GTTGGCTGGG GCAACCTTCT CCAACGTGTG CCTCTGCAGC CTCCCTATCA ACTGCATGAG 
GTGAAGATCC CAATTCAGGA CAACAAGAGC TGTAAGCGGG CTTATAGGAA GAAGTCATCC 
GACGAGCACA AAGCTGTGGC CATCTTTGAC GACATGCTTT GTGCTGGCAC CTCAGGCCGA 
GGCCCCTGTT TTGGTGACTC TGGGGGTCCC TTGGTCTGCT GGAAGAGCAA CAAGTGGATA 
CAGGTGGGCG TGGTCAGCAA GGGGATCGAT TGCAGCAACA ATCTGCCATC AATCTTCTCA 
AGAGTCCAGA GCTCCTTAGC CTGGATCCAT CAACACATCC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Thyroid hormone regulates protease expression and activation of Notch signaling in implantation and embryo development.
The Journal of endocrinology236(1)1-12(2018 Jan)
Piccirilli D,Baldini E,Massimiani M,Camaioni A,Salustri A,Bernardini R,Centanni M,Ulisse S,Moretti C,Campagnolo L

Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis.
PloS one6(8)e23253(2011)
Khalif? M,Young R,Passet B,Halliez S,Vilotte M,Jaffrezic F,Marthey S,B?ringue V,Vaiman D,Le Provost F,Laude H,Vilotte JL

Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors.
PloS one6(11)e27888(2011)
Sharma N,Kumar R,Renaux B,Saifeddine M,Nishikawa S,Mihara K,Ramachandran R,Hollenberg MD,Rancourt DE

Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation.
BMC developmental biology661(2006 Dec)
Sharma N,Liu S,Tang L,Irwin J,Meng G,Rancourt DE

Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty.
Endocrinology147(4)1654-63(2006 Apr)
Vesper AH,Raetzman LT,Camper SA

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Prss28 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報