Dok4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dok4
Entrez Gene ID	114255
Full Name	docking protein 4
General protein information	Preferred Names docking protein 4 Names docking protein 4 downstream of tyrosine kinase 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 C5

mRNA and Protein(s)

mRNA	Protein	Name
XM_030243242.1	XP_030099102.1	docking protein 4 isoform X1
XM_006530579.2	XP_006530642.1	docking protein 4 isoform X1
NM_053246.3	NP_444476.1	docking protein 4
XM_006530579.3	XP_006530642.1	docking protein 4 isoform X1
XM_006530579.4	XP_006530642.1	docking protein 4 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	DOK4	NP_060580.2
Pan troglodytes (chimpanzee)	DOK4	XP_001147359.1
Canis lupus familiaris (dog)	DOK4	XP_544390.2
Bos taurus (cattle)	LOC618756	NP_001077255.1
Gallus gallus (chicken)	DOK4	XP_003641936.1
Danio rerio (zebrafish)	LOC568912	XP_697365.2
	DOK4	XP_001097828.1
Mus musculus (house mouse)	Dok4	NP_444476.1
Rattus norvegicus (Norway rat)	Dok4	NP_001101908.1
Xenopus tropicalis (tropical clawed frog)	dok4	NP_001072558.1

Gene Ontology
Bibliography

Related articles in PubMed

Binding and inhibition of the ternary complex factor Elk-4/Sap1 by the adapter protein Dok-4.
Hooker E, Baldwin C, Roodman V, Batra A, Isa NN, Takano T, Lemay S
The Biochemical journal474(9)1509-1528(2017 04)

BDNF and NT4 play interchangeable roles in gustatory development.
Huang T, Krimm RF
Developmental biology386(2)308-20(2014 Feb)

New insights into Dok-4 PTB domain structure and function.
Hooker E, Baldwin C, Lemay S
Biochemical and biophysical research communications427(1)67-72(2012 Oct)

Endocardiogenesis in embryoid bodies: novel markers identified by gene expression profiling.
Narumiya H, Hidaka K, Shirai M, Terami H, Aburatani H, Morisaki T
Biochemical and biophysical research communications357(4)896-902(2007 Jun)

Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.
Bedirian A, Baldwin C, Abe J, Takano T, Lemay S
The Journal of biological chemistry279(18)19335-49(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Dok-4 can target Elk-4 activity through multiple mechanisms, including binding of the transactivation domain, nuclear exclusion and protein destabilization.
Title: Binding and inhibition of the ternary complex factor Elk-4/Sap1 by the adapter protein Dok-4.

the current study have explored in more detail the structure and function of the Dok-4 PTB domain.
Title: New insights into Dok-4 PTB domain structure and function.

Dok-4 is a constitutively membrane-localized adapter molecule that may function as an inhibitor of tyrosine kinase signaling in epithelial cells.
Title: Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.

The following Dok4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dok4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu20213	NM_053246.3 Latest version!	Mus musculus docking protein 4 (Dok4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu20213	XM_030243242.1 Latest version!	Mus musculus docking protein 4 (Dok4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu20213	XM_006530579.4 Latest version!	Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu20213	XM_006530579.2	Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu20213	XM_006530579.3	Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dok4 ( NM_053246.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_444476.1 Mus musculus docking protein 4 (Dok4), mRNA.

Price & Availability↑

CloneID	OMu20213
Clone ID Related Accession (Same CDS sequence)	XM_030243242.1 , XM_006530579.2 , NM_053246.3 , XM_006530579.3 , XM_006530579.4
Accession Version	NM_053246.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	docking protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC129606.4. On Jul 11, 2009 this sequence version replaced NM_053246.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK156485.1, AK077612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444476.1
CDS	326..1303
Translation	MATNFNDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTAMLPRSAYWHHITGSQNIAEASSYGESYGAAQASSETDLLNRFILLKPKPSQEDSSEAKTPAQ

Target ORF information:

RefSeq Version	NM_053246.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus docking protein 4 (Dok4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053246.3

ORF Insert Sequence:

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dok4 ( XM_030243242.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030099102.1 Mus musculus docking protein 4 (Dok4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu20213
Clone ID Related Accession (Same CDS sequence)	XM_030243242.1 , XM_006530579.2 , NM_053246.3 , XM_006530579.3 , XM_006530579.4
Accession Version	XM_030243242.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	docking protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030099102.1
CDS	211..1188
Translation	MATNFNDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTAMLPRSAYWHHITGSQNIAEASSYGESYGAAQASSETDLLNRFILLKPKPSQEDSSEAKTPAQ

Target ORF information:

RefSeq Version	XM_030243242.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus docking protein 4 (Dok4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030243242.1

ORF Insert Sequence:

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dok4 ( XM_006530579.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006530642.1 Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20213
Clone ID Related Accession (Same CDS sequence)	XM_030243242.1 , XM_006530579.2 , NM_053246.3 , XM_006530579.3 , XM_006530579.4
Accession Version	XM_006530579.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	docking protein 4 isoform X1
Comment

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006530642.1
Translation	MATNFNDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTAMLPRSAYWHHITGSQNIAEASSYGESYGAAQASSETDLLNRFILLKPKPSQEDSSEAKTPAQ

Target ORF information:

RefSeq Version	XM_006530579.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006530579.2

ORF Insert Sequence:

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dok4 ( XM_006530579.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006530642.1 Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20213
Clone ID Related Accession (Same CDS sequence)	XM_030243242.1 , XM_006530579.2 , NM_053246.3 , XM_006530579.3 , XM_006530579.4
Accession Version	XM_006530579.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	docking protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006530579.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006530642.1
CDS	235..1212
Translation	MATNFNDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTAMLPRSAYWHHITGSQNIAEASSYGESYGAAQASSETDLLNRFILLKPKPSQEDSSEAKTPAQ

Target ORF information:

RefSeq Version	XM_006530579.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006530579.3

ORF Insert Sequence:

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dok4 ( XM_006530579.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006530642.1 Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.

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CloneID	OMu20213
Clone ID Related Accession (Same CDS sequence)	XM_030243242.1 , XM_006530579.2 , NM_053246.3 , XM_006530579.3 , XM_006530579.4
Accession Version	XM_006530579.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	docking protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006530579.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006530642.1
CDS	235..1212
Translation	MATNFNDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTAMLPRSAYWHHITGSQNIAEASSYGESYGAAQASSETDLLNRFILLKPKPSQEDSSEAKTPAQ

Target ORF information:

RefSeq Version	XM_006530579.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus docking protein 4 (Dok4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006530579.4

ORF Insert Sequence:

ATGGCGACCA ATTTCAACGA CATCGTCAAG CAAGGCTATG TGAAGATGAA GAGCAGGAAG 
CTCGGGATTT ACCGGAGGTG CTGGCTGGTG TTCCGGAAAT CTTCCAGCAA GGGGCCCCAG 
CGGCTGGAGA AGTATCCTGA TGAGAAGTCC GTGTGCCTCC GAGGCTGCCC CAAGGTGACT 
GAGATTAGCA ACGTCAAGTG TGTCACACGG CTCCCCAAGG AGACCAAGAG GCAGGCGGTG 
GCCATCATAT TCACAGACGA CTCCGCTCGC ACCTTCACTT GTGACTCAGA GCTGGAGGCA 
GAAGAGTGGT ACAAGACACT GTCCGTGGAA TGTCTGGGAT CACGGCTCAA TGACATCAGC 
CTGGGAGAGC CTGACCTCCT GGCTCCAGGA GTACAGTGTG AGCAGACAGA TCGCTTCAAC 
GTCTTCCTGT TACCCTGCCC CAACCTGGAC GTGTATGGGG AGTGCAAGCT GCAGATCACT 
CACGAGAACA TCTACCTCTG GGACATACAC AACCCCCGCG TGAAGCTCGT CTCGTGGCCC 
CTCTGCTCTT TGCGCCGTTA TGGCCGAGAT GCTACGCGCT TTACCTTTGA GGCGGGCAGG 
ATGTGTGACG CTGGGGAAGG GCTCTATACC TTTCAGACAC AGGAGGGGGA GCAGATTTAC 
CAGCGGGTTC ACAGTGCCAC CCTGGCCATC GCCGAGCAGC ACAAGCGGGT CCTGCTGGAG 
ATGGAGAAGA ATGTGAGGCT GCTGAACAAG GGCACCGAGC ACTACTCCTA TCCCTGCACA 
CCCACGGCCA TGCTGCCCCG CAGCGCGTAC TGGCACCATA TCACAGGTTC TCAGAACATT 
GCTGAAGCCT CCAGCTATGG GGAAAGTTAT GGGGCAGCCC AGGCCAGCTC GGAAACAGAC 
CTCCTGAACA GGTTCATCTT GCTTAAGCCA AAGCCCAGTC AGGAGGATAG CAGTGAGGCC 
AAGACCCCTG CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Binding and inhibition of the ternary complex factor Elk-4/Sap1 by the adapter protein Dok-4.
The Biochemical journal474(9)1509-1528(2017 04)
Hooker E,Baldwin C,Roodman V,Batra A,Isa NN,Takano T,Lemay S

BDNF and NT4 play interchangeable roles in gustatory development.
Developmental biology386(2)308-20(2014 Feb)
Huang T,Krimm RF

New insights into Dok-4 PTB domain structure and function.
Biochemical and biophysical research communications427(1)67-72(2012 Oct)
Hooker E,Baldwin C,Lemay S

Endocardiogenesis in embryoid bodies: novel markers identified by gene expression profiling.
Biochemical and biophysical research communications357(4)896-902(2007 Jun)
Narumiya H,Hidaka K,Shirai M,Terami H,Aburatani H,Morisaki T

Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.
The Journal of biological chemistry279(18)19335-49(2004 Apr)
Bedirian A,Baldwin C,Abe J,Takano T,Lemay S

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Dok4 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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