Atxn3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Atxn3
Entrez Gene ID	110616
Full Name	ataxin 3
Synonyms	2210008M02Rik,AI463012,AI647473,ATX3,MJD1,Mjd,Sca3,ataxin-3
General protein information	Preferred Names ataxin 3 Names ataxin-3 Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) homolog machado-Joseph disease protein 1 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 E

mRNA and Protein(s)

mRNA	Protein	Name
XM_030246523.1	XP_030102383.1	ataxin-3 isoform X2
NM_001167914.1	NP_001161386.1	ataxin-3 isoform 2
XM_030246522.1	XP_030102382.1	ataxin-3 isoform X1
XM_030246525.1	XP_030102385.1	ataxin-3 isoform X4
XM_030246524.1	XP_030102384.1	ataxin-3 isoform X3
XM_030246526.1	XP_030102386.1	ataxin-3 isoform X5
NM_029705.3	NP_083981.2	ataxin-3 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ATXN3	XP_001146724.2
	LOC720515	XP_001116022.2
Bos taurus (cattle)	ATXN3	NP_001092686.1
Mus musculus (house mouse)	Atxn3	NP_083981.2
Danio rerio (zebrafish)	atxn3	NP_957398.1
Canis lupus familiaris (dog)	ATXN3	XP_003435073.1
Homo sapiens (human)	ATXN3	NP_001121168.1
Rattus norvegicus (Norway rat)	Atxn3	NP_067734.1
Gallus gallus (chicken)	ATXN3	NP_989688.1
Caenorhabditis elegans (roundworm)	atx-3	NP_506873.1
Xenopus tropicalis (tropical clawed frog)	atxn3	NP_001016389.1

Gene Ontology
Bibliography

Related articles in PubMed

Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.
Ramani B, Panwar B, Moore LR, Wang B, Huang R, Guan Y, Paulson HL
Human molecular genetics26(17)3362-3374(2017 Sep)

Polyglutamine tracts regulate beclin 1-dependent autophagy.
Ashkenazi A, Bento CF, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, Squitieri F, Hardenberg MC, Imarisio S, Menzies FM, Rubinsztein DC
Nature545(7652)108-111(2017 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings identify a novel molecular link between ATX-3 and p53-mediated cell death and provide an explanation for the direct involvement of p53 in SCA3 disease pathogenesis
Title: The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53.

work suggests that in Machado-Joseph disease, mutant ataxin-3 drives an abnormal reduction of ataxin-2 levels, which overactivates poly(A)-binding protein, increases translation of mutant ataxin-3 and other proteins and aggravates Machado-Joseph disease.
Title: Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.

SCA3 knockin mice exhibit robust Atxn3 accumulation both in regions known to be affected in human disease; also display altered splicing of the mutant Atxn3 transcript that results in the formation of a previously described alternative ATXN3 transcript
Title: A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.

We show that chronic VPA treatment did not modify the ATXN3 inclusion load and astrogliosis in affected brain regions However, VPA chronic treatment was able to increase GRP78 protein levels at 30 weeks of age, one of its known neuroprotective effects
Title: Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease.

Data support the importance of ATXN3 in neuronal cells and indicate that an expanded polyQ tract leads to a partial loss of the cellular function of ATXN3 that may be relevant to neurodegeneration.
Title: Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells.

The following Atxn3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Atxn3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu13447	NM_001167914.1 Latest version!	Mus musculus ataxin 3 (Atxn3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OMu13536	NM_029705.3 Latest version!	Mus musculus ataxin 3 (Atxn3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu13447	XM_030246524.1 Latest version!	Mus musculus ataxin 3 (Atxn3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu47539	XM_030246526.1 Latest version!	Mus musculus ataxin 3 (Atxn3), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu85983	XM_030246522.1 Latest version!	Mus musculus ataxin 3 (Atxn3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu85984	XM_030246523.1 Latest version!	Mus musculus ataxin 3 (Atxn3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu85985	XM_030246525.1 Latest version!	Mus musculus ataxin 3 (Atxn3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Atxn3 ( NM_001167914.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001161386.1 Mus musculus ataxin 3 (Atxn3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu13447
Clone ID Related Accession (Same CDS sequence)	NM_001167914.1 , XM_030246524.1
Accession Version	NM_001167914.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	ataxin-3 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC049743.1 and BC087880.1. Transcript Variant: This variant (2) differs at the 3' end compared to variant 1, resulting in an isoform (2) with a shorter C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC049743.1, BB610459.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC AGCCTTCTGG AAATATGGAT GACAGCGGCT TTTTCTCTAT TCAAGTTATA 
AGCAATGCTT TGAAAGTTTG GGGTTTAGAA CTAATCCTGT TCAACAGTCC AGAGTACCAG 
AGGCTCAGAA TTGATCCTAT AAACGAAAGA TCCTTTATAT GCAATTATAA AGAACACTGG 
TTTACAGTTA GAAAATTAGG CAAGCAGTGG TTTAACTTGA ATTCTCTGTT GACGGGTCCA 
GAATTAATAT CAGATACATA CCTCGCACTA TTCTTGGCTC AATTACAGCA AGAAGGTTAT 
TCTATATTTG TTGTTAAGGG TGATCTGCCA GATTGTGAAG CTGACCAACT TTTGCAGATG 
ATCAAGGTCC AACAGATGCA TCGACCAAAA CTTATTGGAG AGGAACTTGC ACATCTGAAA 
GAGCAGAGTG CCCTCAAAGC AGACCTGGAG CGCGTCTTAG AAGCAGCTGA TGGGTCGGGC 
ATATTTGATG AAGATGAGGA TGATTTACAG AGGGCTCTAG CCATAAGTCG CCAGGAAATC 
GACATGGAGG ATGAAGAAGC TGATCTCCGC AGGGCCATTC AGCTCAGTAT GCAAGGTAGT 
TCCAGAAGTA TGTGTGAAAA TAGTCCACAG ACATCAAGTC CAGATCTCTC TTCAGAAGAG 
CTGCGGAGGA GACGAGAAGC CTACTTTGAA AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001161386.1
CDS	87..962
Translation	MESIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERLRMAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIKVQQMHRPKLIGEELAHLKEQSALKADLERVLEAADGSGIFDEDEDDLQRALAISRQEIDMEDEEADLRRAIQLSMQGSSRSMCENSPQTSSPDLSSEELRRRREAYFEK

Target ORF information:

RefSeq Version	NM_001167914.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ataxin 3 (Atxn3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001167914.1

ORF Insert Sequence:

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC AGCCTTCTGG AAATATGGAT GACAGCGGCT TTTTCTCTAT TCAAGTTATA 
AGCAATGCTT TGAAAGTTTG GGGTTTAGAA CTAATCCTGT TCAACAGTCC AGAGTACCAG 
AGGCTCAGAA TTGATCCTAT AAACGAAAGA TCCTTTATAT GCAATTATAA AGAACACTGG 
TTTACAGTTA GAAAATTAGG CAAGCAGTGG TTTAACTTGA ATTCTCTGTT GACGGGTCCA 
GAATTAATAT CAGATACATA CCTCGCACTA TTCTTGGCTC AATTACAGCA AGAAGGTTAT 
TCTATATTTG TTGTTAAGGG TGATCTGCCA GATTGTGAAG CTGACCAACT TTTGCAGATG 
ATCAAGGTCC AACAGATGCA TCGACCAAAA CTTATTGGAG AGGAACTTGC ACATCTGAAA 
GAGCAGAGTG CCCTCAAAGC AGACCTGGAG CGCGTCTTAG AAGCAGCTGA TGGGTCGGGC 
ATATTTGATG AAGATGAGGA TGATTTACAG AGGGCTCTAG CCATAAGTCG CCAGGAAATC 
GACATGGAGG ATGAAGAAGC TGATCTCCGC AGGGCCATTC AGCTCAGTAT GCAAGGTAGT 
TCCAGAAGTA TGTGTGAAAA TAGTCCACAG ACATCAAGTC CAGATCTCTC TTCAGAAGAG 
CTGCGGAGGA GACGAGAAGC CTACTTTGAA AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atxn3 ( NM_029705.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083981.2 Mus musculus ataxin 3 (Atxn3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu13536
Clone ID Related Accession (Same CDS sequence)	NM_029705.3
Accession Version	NM_029705.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	ataxin-3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC049743.1, AK030842.1, BX526801.1 and BQ174976.1. On Nov 19, 2009 this sequence version replaced NM_029705.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK030842.1, SRR6238556.2885322.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC AGCCTTCTGG AAATATGGAT GACAGCGGCT TTTTCTCTAT TCAAGTTATA 
AGCAATGCTT TGAAAGTTTG GGGTTTAGAA CTAATCCTGT TCAACAGTCC AGAGTACCAG 
AGGCTCAGAA TTGATCCTAT AAACGAAAGA TCCTTTATAT GCAATTATAA AGAACACTGG 
TTTACAGTTA GAAAATTAGG CAAGCAGTGG TTTAACTTGA ATTCTCTGTT GACGGGTCCA 
GAATTAATAT CAGATACATA CCTCGCACTA TTCTTGGCTC AATTACAGCA AGAAGGTTAT 
TCTATATTTG TTGTTAAGGG TGATCTGCCA GATTGTGAAG CTGACCAACT TTTGCAGATG 
ATCAAGGTCC AACAGATGCA TCGACCAAAA CTTATTGGAG AGGAACTTGC ACATCTGAAA 
GAGCAGAGTG CCCTCAAAGC AGACCTGGAG CGCGTCTTAG AAGCAGCTGA TGGGTCGGGC 
ATATTTGATG AAGATGAGGA TGATTTACAG AGGGCTCTAG CCATAAGTCG CCAGGAAATC 
GACATGGAGG ATGAAGAAGC TGATCTCCGC AGGGCCATTC AGCTCAGTAT GCAAGGTAGT 
TCCAGAAGTA TGTGTGAAAA TAGTCCACAG ACATCAAGTC CAGATCTCTC TTCAGAAGAG 
CTGCGGAGGA GACGAGAAGC CTACTTTGAA AAGCAACAGC AGCAGCAGCA GGAGGTAGAC 
CGACCTGGAC CCCTTTCATA TCCACGTGAA AGACCGACCA CAAGTTCAGG AGGACGTAGG 
AGCGACCAAG GAGGCGACGC TGTGAGTGAA GAGGACATGC TTCGGGCAGC TGTGACCATG 
TCTTTAGAAA CTGCTAAAGA CAACTTGAAA GCAGAAAGAA AAAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083981.2
CDS	87..1154
Translation	MESIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERLRMAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIKVQQMHRPKLIGEELAHLKEQSALKADLERVLEAADGSGIFDEDEDDLQRALAISRQEIDMEDEEADLRRAIQLSMQGSSRSMCENSPQTSSPDLSSEELRRRREAYFEKQQQQQQEVDRPGPLSYPRERPTTSSGGRRSDQGGDAVSEEDMLRAAVTMSLETAKDNLKAERKK

Target ORF information:

RefSeq Version	NM_029705.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ataxin 3 (Atxn3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029705.3

ORF Insert Sequence:

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC AGCCTTCTGG AAATATGGAT GACAGCGGCT TTTTCTCTAT TCAAGTTATA 
AGCAATGCTT TGAAAGTTTG GGGTTTAGAA CTAATCCTGT TCAACAGTCC AGAGTACCAG 
AGGCTCAGAA TTGATCCTAT AAACGAAAGA TCCTTTATAT GCAATTATAA AGAACACTGG 
TTTACAGTTA GAAAATTAGG CAAGCAGTGG TTTAACTTGA ATTCTCTGTT GACGGGTCCA 
GAATTAATAT CAGATACATA CCTCGCACTA TTCTTGGCTC AATTACAGCA AGAAGGTTAT 
TCTATATTTG TTGTTAAGGG TGATCTGCCA GATTGTGAAG CTGACCAACT TTTGCAGATG 
ATCAAGGTCC AACAGATGCA TCGACCAAAA CTTATTGGAG AGGAACTTGC ACATCTGAAA 
GAGCAGAGTG CCCTCAAAGC AGACCTGGAG CGCGTCTTAG AAGCAGCTGA TGGGTCGGGC 
ATATTTGATG AAGATGAGGA TGATTTACAG AGGGCTCTAG CCATAAGTCG CCAGGAAATC 
GACATGGAGG ATGAAGAAGC TGATCTCCGC AGGGCCATTC AGCTCAGTAT GCAAGGTAGT 
TCCAGAAGTA TGTGTGAAAA TAGTCCACAG ACATCAAGTC CAGATCTCTC TTCAGAAGAG 
CTGCGGAGGA GACGAGAAGC CTACTTTGAA AAGCAACAGC AGCAGCAGCA GGAGGTAGAC 
CGACCTGGAC CCCTTTCATA TCCACGTGAA AGACCGACCA CAAGTTCAGG AGGACGTAGG 
AGCGACCAAG GAGGCGACGC TGTGAGTGAA GAGGACATGC TTCGGGCAGC TGTGACCATG 
TCTTTAGAAA CTGCTAAAGA CAACTTGAAA GCAGAAAGAA AAAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atxn3 ( XM_030246524.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102384.1 Mus musculus ataxin 3 (Atxn3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu13447
Clone ID Related Accession (Same CDS sequence)	NM_001167914.1 , XM_030246524.1
Accession Version	XM_030246524.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ataxin-3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC AGCCTTCTGG AAATATGGAT GACAGCGGCT TTTTCTCTAT TCAAGTTATA 
AGCAATGCTT TGAAAGTTTG GGGTTTAGAA CTAATCCTGT TCAACAGTCC AGAGTACCAG 
AGGCTCAGAA TTGATCCTAT AAACGAAAGA TCCTTTATAT GCAATTATAA AGAACACTGG 
TTTACAGTTA GAAAATTAGG CAAGCAGTGG TTTAACTTGA ATTCTCTGTT GACGGGTCCA 
GAATTAATAT CAGATACATA CCTCGCACTA TTCTTGGCTC AATTACAGCA AGAAGGTTAT 
TCTATATTTG TTGTTAAGGG TGATCTGCCA GATTGTGAAG CTGACCAACT TTTGCAGATG 
ATCAAGGTCC AACAGATGCA TCGACCAAAA CTTATTGGAG AGGAACTTGC ACATCTGAAA 
GAGCAGAGTG CCCTCAAAGC AGACCTGGAG CGCGTCTTAG AAGCAGCTGA TGGGTCGGGC 
ATATTTGATG AAGATGAGGA TGATTTACAG AGGGCTCTAG CCATAAGTCG CCAGGAAATC 
GACATGGAGG ATGAAGAAGC TGATCTCCGC AGGGCCATTC AGCTCAGTAT GCAAGGTAGT 
TCCAGAAGTA TGTGTGAAAA TAGTCCACAG ACATCAAGTC CAGATCTCTC TTCAGAAGAG 
CTGCGGAGGA GACGAGAAGC CTACTTTGAA AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102384.1
CDS	965..1840
Translation	MESIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERLRMAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIKVQQMHRPKLIGEELAHLKEQSALKADLERVLEAADGSGIFDEDEDDLQRALAISRQEIDMEDEEADLRRAIQLSMQGSSRSMCENSPQTSSPDLSSEELRRRREAYFEK

Target ORF information:

RefSeq Version	XM_030246524.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ataxin 3 (Atxn3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246524.1

ORF Insert Sequence:

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC AGCCTTCTGG AAATATGGAT GACAGCGGCT TTTTCTCTAT TCAAGTTATA 
AGCAATGCTT TGAAAGTTTG GGGTTTAGAA CTAATCCTGT TCAACAGTCC AGAGTACCAG 
AGGCTCAGAA TTGATCCTAT AAACGAAAGA TCCTTTATAT GCAATTATAA AGAACACTGG 
TTTACAGTTA GAAAATTAGG CAAGCAGTGG TTTAACTTGA ATTCTCTGTT GACGGGTCCA 
GAATTAATAT CAGATACATA CCTCGCACTA TTCTTGGCTC AATTACAGCA AGAAGGTTAT 
TCTATATTTG TTGTTAAGGG TGATCTGCCA GATTGTGAAG CTGACCAACT TTTGCAGATG 
ATCAAGGTCC AACAGATGCA TCGACCAAAA CTTATTGGAG AGGAACTTGC ACATCTGAAA 
GAGCAGAGTG CCCTCAAAGC AGACCTGGAG CGCGTCTTAG AAGCAGCTGA TGGGTCGGGC 
ATATTTGATG AAGATGAGGA TGATTTACAG AGGGCTCTAG CCATAAGTCG CCAGGAAATC 
GACATGGAGG ATGAAGAAGC TGATCTCCGC AGGGCCATTC AGCTCAGTAT GCAAGGTAGT 
TCCAGAAGTA TGTGTGAAAA TAGTCCACAG ACATCAAGTC CAGATCTCTC TTCAGAAGAG 
CTGCGGAGGA GACGAGAAGC CTACTTTGAA AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atxn3 ( XM_030246526.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102386.1 Mus musculus ataxin 3 (Atxn3), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OMu47539
Clone ID Related Accession (Same CDS sequence)	XM_030246526.1
Accession Version	XM_030246526.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ataxin-3 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC AGCCTTCTGG AAATATGGAT GACAGCGGCT TTTTCTCTAT TCAAGTTATA 
AGCAATGCTT TGAAAGTTTG GGGTTTAGAA CTAATCCTGT TCAACAGTCC AGAGTACCAG 
AGGCTCAGAA TTGATCCTAT AAACGAAAGA TCCTTTATAT GCAATTATAA AGAACACTGG 
TTTACAGTTA GAAAATTAGG CAAGCAGTGG TTTAACTTGA ATTCTCTGTT GACGGGTCCA 
GAATTAATAT CAGATACATA CCTCGCACTA TTCTTGGCTC AATTACAGCA AGAAGGTTAT 
TCTATATTTG TTGTTAAGGG TGATCTGCCA GATTGTGAAG CTGACCAACT TTTGCAGATG 
ATCAAGGTCC AACAGATGCA TCGACCAAAA CTTATTGGAG AGGAACTTGC ACATCTGAAA 
GAGCAGAGTG CCCTCAAAGC AGACCTGGAG CGCGTCTTAG AAGCAGCTGA TGGGTCGGGC 
ATATTTGATG AAGATGAGGA TGATTTACAG AGGGCTCTAG CCATAAGTCG CCAGGAAATC 
GACATGGAGG ATGAAGAAGC TGATCTCCGC AGGGCCATTC AGCTCAGTAT GCAAGTTCCA 
GAAGTATGTG TGAAAATAGT CCACAGACAT CAAGTCCAGA TCTCTCTTCA GAAGAGCTGC 
GGAGGAGACG AGAAGCCTAC TTTGAAAAGT AAAGTAGTTG GTACAGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102386.1
CDS	965..1855
Translation	MESIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERLRMAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIKVQQMHRPKLIGEELAHLKEQSALKADLERVLEAADGSGIFDEDEDDLQRALAISRQEIDMEDEEADLRRAIQLSMQVPEVCVKIVHRHQVQISLQKSCGGDEKPTLKSKVVGTD

Target ORF information:

RefSeq Version	XM_030246526.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ataxin 3 (Atxn3), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246526.1

ORF Insert Sequence:

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC AGCCTTCTGG AAATATGGAT GACAGCGGCT TTTTCTCTAT TCAAGTTATA 
AGCAATGCTT TGAAAGTTTG GGGTTTAGAA CTAATCCTGT TCAACAGTCC AGAGTACCAG 
AGGCTCAGAA TTGATCCTAT AAACGAAAGA TCCTTTATAT GCAATTATAA AGAACACTGG 
TTTACAGTTA GAAAATTAGG CAAGCAGTGG TTTAACTTGA ATTCTCTGTT GACGGGTCCA 
GAATTAATAT CAGATACATA CCTCGCACTA TTCTTGGCTC AATTACAGCA AGAAGGTTAT 
TCTATATTTG TTGTTAAGGG TGATCTGCCA GATTGTGAAG CTGACCAACT TTTGCAGATG 
ATCAAGGTCC AACAGATGCA TCGACCAAAA CTTATTGGAG AGGAACTTGC ACATCTGAAA 
GAGCAGAGTG CCCTCAAAGC AGACCTGGAG CGCGTCTTAG AAGCAGCTGA TGGGTCGGGC 
ATATTTGATG AAGATGAGGA TGATTTACAG AGGGCTCTAG CCATAAGTCG CCAGGAAATC 
GACATGGAGG ATGAAGAAGC TGATCTCCGC AGGGCCATTC AGCTCAGTAT GCAAGTTCCA 
GAAGTATGTG TGAAAATAGT CCACAGACAT CAAGTCCAGA TCTCTCTTCA GAAGAGCTGC 
GGAGGAGACG AGAAGCCTAC TTTGAAAAGT AAAGTAGTTG GTACAGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atxn3 ( XM_030246522.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102382.1 Mus musculus ataxin 3 (Atxn3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu85983
Clone ID Related Accession (Same CDS sequence)	XM_030246522.1
Accession Version	XM_030246522.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ataxin-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC CTTCTGGAAA TATGGATGAC AGCGGCTTTT TCTCTATTCA AGTTATAAGC 
AATGCTTTGA AAGTTTGGGG TTTAGAACTA ATCCTGTTCA ACAGTCCAGA GTACCAGAGG 
CTCAGAATTG ATCCTATAAA CGAAAGATCC TTTATATGCA ATTATAAAGA ACACTGGTTT 
ACAGTTAGAA AATTAGGCAA GCAGTGGTTT AACTTGAATT CTCTGTTGAC GGGTCCAGAA 
TTAATATCAG ATACATACCT CGCACTATTC TTGGCTCAAT TACAGCAAGA AGGTTATTCT 
ATATTTGTTG TTAAGGGTGA TCTGCCAGAT TGTGAAGCTG ACCAACTTTT GCAGATGATC 
AAGGTCCAAC AGATGCATCG ACCAAAACTT ATTGGAGAGG AACTTGCACA TCTGAAAGAG 
CAGAGTGCCC TCAAAGCAGA CCTGGAGCGC GTCTTAGAAG CAGCTGATGG GTCGGGCATA 
TTTGATGAAG ATGAGGATGA TTTACAGAGG GCTCTAGCCA TAAGTCGCCA GGAAATCGAC 
ATGGAGGATG AAGAAGCTGA TCTCCGCAGG GCCATTCAGC TCAGTATGCA AGGTAGTTCC 
AGAAGTATGT GTGAAAATAG TCCACAGACA TCAAGTCCAG ATCTCTCTTC AGAAGAGCTG 
CGGAGGAGAC GAGAAGCCTA CTTTGAAAAG CAACAGCAGC AGCAGCAGGA GGTAGACCGA 
CCTGGACCCC TTTCATATCC ACGTGAAAGA CCGACCACAA GTTCAGGAGG ACGTAGGAGC 
GACCAAGGAG GCGACGCTGT GAGTGAAGAG GACATGCTTC GGGCAGCTGT GACCATGTCT 
TTAGAAACTG CTAAAGACAA CTTGAAAGCA GAAAGAAAAA AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102382.1
CDS	965..2029
Translation	MESIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERLRMAEGGVTSEDYRTFLQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIKVQQMHRPKLIGEELAHLKEQSALKADLERVLEAADGSGIFDEDEDDLQRALAISRQEIDMEDEEADLRRAIQLSMQGSSRSMCENSPQTSSPDLSSEELRRRREAYFEKQQQQQQEVDRPGPLSYPRERPTTSSGGRRSDQGGDAVSEEDMLRAAVTMSLETAKDNLKAERKK

Target ORF information:

RefSeq Version	XM_030246522.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ataxin 3 (Atxn3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246522.1

ORF Insert Sequence:

ATGGAGTCCA TCTTCCACGA GAAACAAGAA GGCTCACTTT GTGCTCAGCA TTGCCTGAAT 
AACCTATTGC AAGGAGAGTA TTTTAGCCCT GTGGAGCTAT CCTCAATTGC ACACCAGCTG 
GATGAAGAGG AGAGGCTGAG AATGGCAGAA GGGGGAGTCA CTAGTGAAGA CTACCGCACA 
TTTTTACAGC CTTCTGGAAA TATGGATGAC AGCGGCTTTT TCTCTATTCA AGTTATAAGC 
AATGCTTTGA AAGTTTGGGG TTTAGAACTA ATCCTGTTCA ACAGTCCAGA GTACCAGAGG 
CTCAGAATTG ATCCTATAAA CGAAAGATCC TTTATATGCA ATTATAAAGA ACACTGGTTT 
ACAGTTAGAA AATTAGGCAA GCAGTGGTTT AACTTGAATT CTCTGTTGAC GGGTCCAGAA 
TTAATATCAG ATACATACCT CGCACTATTC TTGGCTCAAT TACAGCAAGA AGGTTATTCT 
ATATTTGTTG TTAAGGGTGA TCTGCCAGAT TGTGAAGCTG ACCAACTTTT GCAGATGATC 
AAGGTCCAAC AGATGCATCG ACCAAAACTT ATTGGAGAGG AACTTGCACA TCTGAAAGAG 
CAGAGTGCCC TCAAAGCAGA CCTGGAGCGC GTCTTAGAAG CAGCTGATGG GTCGGGCATA 
TTTGATGAAG ATGAGGATGA TTTACAGAGG GCTCTAGCCA TAAGTCGCCA GGAAATCGAC 
ATGGAGGATG AAGAAGCTGA TCTCCGCAGG GCCATTCAGC TCAGTATGCA AGGTAGTTCC 
AGAAGTATGT GTGAAAATAG TCCACAGACA TCAAGTCCAG ATCTCTCTTC AGAAGAGCTG 
CGGAGGAGAC GAGAAGCCTA CTTTGAAAAG CAACAGCAGC AGCAGCAGGA GGTAGACCGA 
CCTGGACCCC TTTCATATCC ACGTGAAAGA CCGACCACAA GTTCAGGAGG ACGTAGGAGC 
GACCAAGGAG GCGACGCTGT GAGTGAAGAG GACATGCTTC GGGCAGCTGT GACCATGTCT 
TTAGAAACTG CTAAAGACAA CTTGAAAGCA GAAAGAAAAA AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atxn3 ( XM_030246523.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102383.1 Mus musculus ataxin 3 (Atxn3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu85984
Clone ID Related Accession (Same CDS sequence)	XM_030246523.1
Accession Version	XM_030246523.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ataxin-3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAAG GGGGAGTCAC TAGTGAAGAC TACCGCACAT TTTTACAGCA GCCTTCTGGA 
AATATGGATG ACAGCGGCTT TTTCTCTATT CAAGTTATAA GCAATGCTTT GAAAGTTTGG 
GGTTTAGAAC TAATCCTGTT CAACAGTCCA GAGTACCAGA GGCTCAGAAT TGATCCTATA 
AACGAAAGAT CCTTTATATG CAATTATAAA GAACACTGGT TTACAGTTAG AAAATTAGGC 
AAGCAGTGGT TTAACTTGAA TTCTCTGTTG ACGGGTCCAG AATTAATATC AGATACATAC 
CTCGCACTAT TCTTGGCTCA ATTACAGCAA GAAGGTTATT CTATATTTGT TGTTAAGGGT 
GATCTGCCAG ATTGTGAAGC TGACCAACTT TTGCAGATGA TCAAGGTCCA ACAGATGCAT 
CGACCAAAAC TTATTGGAGA GGAACTTGCA CATCTGAAAG AGCAGAGTGC CCTCAAAGCA 
GACCTGGAGC GCGTCTTAGA AGCAGCTGAT GGGTCGGGCA TATTTGATGA AGATGAGGAT 
GATTTACAGA GGGCTCTAGC CATAAGTCGC CAGGAAATCG ACATGGAGGA TGAAGAAGCT 
GATCTCCGCA GGGCCATTCA GCTCAGTATG CAAGGTAGTT CCAGAAGTAT GTGTGAAAAT 
AGTCCACAGA CATCAAGTCC AGATCTCTCT TCAGAAGAGC TGCGGAGGAG ACGAGAAGCC 
TACTTTGAAA AGCAACAGCA GCAGCAGCAG GAGGTAGACC GACCTGGACC CCTTTCATAT 
CCACGTGAAA GACCGACCAC AAGTTCAGGA GGACGTAGGA GCGACCAAGG AGGCGACGCT 
GTGAGTGAAG AGGACATGCT TCGGGCAGCT GTGACCATGT CTTTAGAAAC TGCTAAAGAC 
AACTTGAAAG CAGAAAGAAA AAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102383.1
CDS	296..1222
Translation	MAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIKVQQMHRPKLIGEELAHLKEQSALKADLERVLEAADGSGIFDEDEDDLQRALAISRQEIDMEDEEADLRRAIQLSMQGSSRSMCENSPQTSSPDLSSEELRRRREAYFEKQQQQQQEVDRPGPLSYPRERPTTSSGGRRSDQGGDAVSEEDMLRAAVTMSLETAKDNLKAERKK

Target ORF information:

RefSeq Version	XM_030246523.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ataxin 3 (Atxn3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246523.1

ORF Insert Sequence:

ATGGCAGAAG GGGGAGTCAC TAGTGAAGAC TACCGCACAT TTTTACAGCA GCCTTCTGGA 
AATATGGATG ACAGCGGCTT TTTCTCTATT CAAGTTATAA GCAATGCTTT GAAAGTTTGG 
GGTTTAGAAC TAATCCTGTT CAACAGTCCA GAGTACCAGA GGCTCAGAAT TGATCCTATA 
AACGAAAGAT CCTTTATATG CAATTATAAA GAACACTGGT TTACAGTTAG AAAATTAGGC 
AAGCAGTGGT TTAACTTGAA TTCTCTGTTG ACGGGTCCAG AATTAATATC AGATACATAC 
CTCGCACTAT TCTTGGCTCA ATTACAGCAA GAAGGTTATT CTATATTTGT TGTTAAGGGT 
GATCTGCCAG ATTGTGAAGC TGACCAACTT TTGCAGATGA TCAAGGTCCA ACAGATGCAT 
CGACCAAAAC TTATTGGAGA GGAACTTGCA CATCTGAAAG AGCAGAGTGC CCTCAAAGCA 
GACCTGGAGC GCGTCTTAGA AGCAGCTGAT GGGTCGGGCA TATTTGATGA AGATGAGGAT 
GATTTACAGA GGGCTCTAGC CATAAGTCGC CAGGAAATCG ACATGGAGGA TGAAGAAGCT 
GATCTCCGCA GGGCCATTCA GCTCAGTATG CAAGGTAGTT CCAGAAGTAT GTGTGAAAAT 
AGTCCACAGA CATCAAGTCC AGATCTCTCT TCAGAAGAGC TGCGGAGGAG ACGAGAAGCC 
TACTTTGAAA AGCAACAGCA GCAGCAGCAG GAGGTAGACC GACCTGGACC CCTTTCATAT 
CCACGTGAAA GACCGACCAC AAGTTCAGGA GGACGTAGGA GCGACCAAGG AGGCGACGCT 
GTGAGTGAAG AGGACATGCT TCGGGCAGCT GTGACCATGT CTTTAGAAAC TGCTAAAGAC 
AACTTGAAAG CAGAAAGAAA AAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atxn3 ( XM_030246525.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102385.1 Mus musculus ataxin 3 (Atxn3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OMu85985
Clone ID Related Accession (Same CDS sequence)	XM_030246525.1
Accession Version	XM_030246525.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ataxin-3 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAAGG TCCAACAGAT GCATCGACCA AAACTTATTG GAGAGGAACT TGCACATCTG 
AAAGAGCAGA GTGCCCTCAA AGCAGACCTG GAGCGCGTCT TAGAAGCAGC TGATGGGTCG 
GGCATATTTG ATGAAGATGA GGATGATTTA CAGAGGGCTC TAGCCATAAG TCGCCAGGAA 
ATCGACATGG AGGATGAAGA AGCTGATCTC CGCAGGGCCA TTCAGCTCAG TATGCAAGGT 
AGTTCCAGAA GTATGTGTGA AAATAGTCCA CAGACATCAA GTCCAGATCT CTCTTCAGAA 
GAGCTGCGGA GGAGACGAGA AGCCTACTTT GAAAAGCAAC AGCAGCAGCA GCAGGAGGTA 
GACCGACCTG GACCCCTTTC ATATCCACGT GAAAGACCGA CCACAAGTTC AGGAGGACGT 
AGGAGCGACC AAGGAGGCGA CGCTGTGAGT GAAGAGGACA TGCTTCGGGC AGCTGTGACC 
ATGTCTTTAG AAACTGCTAA AGACAACTTG AAAGCAGAAA GAAAAAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102385.1
CDS	559..1089
Translation	MIKVQQMHRPKLIGEELAHLKEQSALKADLERVLEAADGSGIFDEDEDDLQRALAISRQEIDMEDEEADLRRAIQLSMQGSSRSMCENSPQTSSPDLSSEELRRRREAYFEKQQQQQQEVDRPGPLSYPRERPTTSSGGRRSDQGGDAVSEEDMLRAAVTMSLETAKDNLKAERKK

Target ORF information:

RefSeq Version	XM_030246525.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ataxin 3 (Atxn3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246525.1

ORF Insert Sequence:

ATGATCAAGG TCCAACAGAT GCATCGACCA AAACTTATTG GAGAGGAACT TGCACATCTG 
AAAGAGCAGA GTGCCCTCAA AGCAGACCTG GAGCGCGTCT TAGAAGCAGC TGATGGGTCG 
GGCATATTTG ATGAAGATGA GGATGATTTA CAGAGGGCTC TAGCCATAAG TCGCCAGGAA 
ATCGACATGG AGGATGAAGA AGCTGATCTC CGCAGGGCCA TTCAGCTCAG TATGCAAGGT 
AGTTCCAGAA GTATGTGTGA AAATAGTCCA CAGACATCAA GTCCAGATCT CTCTTCAGAA 
GAGCTGCGGA GGAGACGAGA AGCCTACTTT GAAAAGCAAC AGCAGCAGCA GCAGGAGGTA 
GACCGACCTG GACCCCTTTC ATATCCACGT GAAAGACCGA CCACAAGTTC AGGAGGACGT 
AGGAGCGACC AAGGAGGCGA CGCTGTGAGT GAAGAGGACA TGCTTCGGGC AGCTGTGACC 
ATGTCTTTAG AAACTGCTAA AGACAACTTG AAAGCAGAAA GAAAAAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.
Human molecular genetics26(17)3362-3374(2017 Sep)
Ramani B,Panwar B,Moore LR,Wang B,Huang R,Guan Y,Paulson HL

Polyglutamine tracts regulate beclin 1-dependent autophagy.
Nature545(7652)108-111(2017 05)
Ashkenazi A,Bento CF,Ricketts T,Vicinanza M,Siddiqi F,Pavel M,Squitieri F,Hardenberg MC,Imarisio S,Menzies FM,Rubinsztein DC

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Atxn3 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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