Dek cDNA ORF clone, Mus musculus(house mouse)

Roles of DEK in the endometrium of mice in early pregnancy.
Yang Y, Wu M, Geng Y, Liu X, Yang Y, Chen X, Ding Y, He J, Wang Y, Xie L
Gene642261-267(2018 Feb)

Neuroanatomical Distribution of DEK Protein in Corticolimbic Circuits Associated with Learning and Memory in Adult Male and Female Mice.
Ghisays V, Nguyen ET, Streicher J, Pease NA, Fitzgerald M, Estrada CM, Franco-Villanueva A, Privette Vinnedge L, Solomon MB
Neuroscience371254-267(2017 Nov)

DEK is required for homologous recombination repair of DNA breaks.
Smith EA, Gole B, Willis NA, Soria R, Starnes LM, Krumpelbeck EF, Jegga AG, Ali AM, Guo H, Meetei AR, Andreassen PR, Kappes F, Vinnedge LM, Daniel JA, Scully R, Wiesm?ller L, Wells SI
Scientific reports744662(2017 Mar)

DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis.
Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM
Nature communications814252(2017 Feb)

Data suggests that DEK participates in the process of embryo implantation and might play a role in influencing stromal cell decidualization through mediating cell proliferation, apoptosis and DNA damage.
Title: Roles of DEK in the endometrium of mice in early pregnancy.

Studies demonstrate that DEK overexpression, due in part to Ron receptor activation, drives breast cancer progression through the induction of Wnt/beta-catenin signaling.
Title: The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers.

data demonstrate that DEK stimulates HNSCC cellular growth and identify DeltaNp63 as a novel DEK effector
Title: DEK promotes HPV-positive and -negative head and neck cancer cell proliferation.

DEK expression during normal hematopoiesis did reveal a relationship with specific cell types implicating a distinct function during myeloid differentiation
Title: DEK oncogene expression during normal hematopoiesis and in Acute Myeloid Leukemia (AML).

Results highlight a novel function of DEK as a guardian of chromatin by restricting widespread histone access, and in particular by modulating differential H3.3 loading in specific chromatin areas.
Title: The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity.