Itga1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itga1
Entrez Gene ID	109700
Full Name	integrin alpha 1
Synonyms	CD49A,E130012M19Rik,Vla1
General protein information	Preferred Names integrin alpha 1 Names integrin alpha-1 CD49 antigen-like family member A VLA-1 laminin and collagen receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 D2.2\|13 64.61 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033228.3	NP_001028400.2	integrin alpha-1 precursor

Pathways from BioSystems

Homologies

	ITGA1	XP_001094788.1
Rattus norvegicus (Norway rat)	Itga1	NP_112256.1
Gallus gallus (chicken)	ITGA1	NP_990400.1
Pan troglodytes (chimpanzee)	ITGA1	XP_517769.2
Canis lupus familiaris (dog)	ITGA1	XP_005619392.1
Mus musculus (house mouse)	Itga1	NP_001028400.2
Danio rerio (zebrafish)	itga1	XP_699485.4
Xenopus tropicalis (tropical clawed frog)	itga1	XP_002933090.2
Homo sapiens (human)	ITGA1	NP_852478.1

Gene Ontology
Bibliography

Related articles in PubMed

Semaphorin7A aggravates coxsackievirusB3-induced viral myocarditis by increasing ?1?1-integrin macrophages and subsequent enhanced inflammatory response.
Wu X, Meng Y, Wang C, Yue Y, Dong C, Xiong S
Journal of molecular and cellular cardiology11448-57(2017 Nov)

Cross-talk of SFRP4, integrin ?1?1, and Notch1 inhibits cardiac differentiation of P19CL6 cells.
Tian Y, Wang W, Lu Q, Chen P, Ma K, Jia Z, Zhou C
Cellular signalling28(11)1806-15(2016 Nov)

Langerhans Cells Suppress CD49a+ NK Cell-Mediated Skin Inflammation.
Scholz F, Naik S, Sutterwala FS, Kaplan DH
Journal of immunology (Baltimore, Md. : 1950)195(5)2335-42(2015 Sep)

Integrin ?1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance.
Williams AS, Kang L, Zheng J, Grueter C, Bracy DP, James FD, Pozzi A, Wasserman DH
The Journal of biological chemistry290(10)6546-57(2015 Mar)

Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice.
Wang H, Shun MC, Dickson AK, Engelman AN
PloS one10(9)e0137797(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the cross-talk between SFRP4, integrin alpha1beta1, and Notch1 suppresses the cardiac differentiation of P19CL6 cells.
Title: Cross-talk of SFRP4, integrin ?1?1, and Notch1 inhibits cardiac differentiation of P19CL6 cells.

Data show that in the absence of Langerhans Cells, CD49a(+) liver NK cells display an inappropriately proinflammatory phenotype that results in increased local skin inflammation.
Title: Langerhans Cells Suppress CD49a+ NK Cell-Mediated Skin Inflammation.

The decrease in hepatic lipid accumulation in HF-fed itga1(-/-) mice was associated with altered free fatty acid metabolism. These studies establish a role for integrin signaling in facilitating hepatic insulin action
Title: Integrin ?1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance.

Synthesis and modeling of linear and cyclic KTS-containing peptides is described that leads to their use as inhibitors of integrin alpha1beta1/alpha2beta1-mediated adhesion and other antiangiogenetic activity in human serum.
Title: Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of ?1?1/?2?1 integrins with antiangiogenic activity.

a crosstalk between integrin alpha1beta1 and TbetaRII is essential for TbetaRII-mediated SMAD activation and fibrotic signaling pathways
Title: Integrin-mediated type II TGF-? receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling.

The following Itga1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itga1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22204	NM_001033228.3 Latest version!	Mus musculus integrin alpha 1 (Itga1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itga1 ( NM_001033228.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028400.2 Mus musculus integrin alpha 1 (Itga1), mRNA.

Price & Availability↑

CloneID	OMu22204
Clone ID Related Accession (Same CDS sequence)	NM_001033228.3
Accession Version	NM_001033228.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	integrin alpha-1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK035870.1, AK040830.1, AK053377.1 and AK033533.1. On Jul 25, 2007 this sequence version replaced NM_001033228.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK035870.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGTCCCCA GGCGTCCTGC TAGCCTAGAG GTCACTGTAG CCTGCATCTG GCTTCTCACC 
GTTATCCTAG GCGTCTGCAT CTCCTTCAAC GTTGATGTCA AAAACTCCAT GAGCTTCAGT 
GGTCCAGTGG AGGACATGTT TGGATACACC GTTCAACAGT ATGAAAACGA AGAAGGCAAA 
TGGGTTCTTA TTGGTTCTCC TTTAGTTGGC CAACCCAAAG CAAGAACTGG AGATGTCTAT 
AAGTGTCCAG TTGGGAGAGA GAGATCAATG CCTTGTGTGA AGTTGGATTT ACCAGTTAAC 
ACATCGATTC CTAATGTCAC AGAAATAAAG GAAAACATGA CATTTGGATC AACTTTAGTC 
ACCAATCCGA AGGGAGGATT TCTGGCATGT GGGCCCTTGT ATGCCTATAG ATGTGGACAT 
TTGCATTATA CGACTGGCAT ATGTTCTGAT GTCAGCCCTA CATTTCAAGT TGTGAACTCG 
TTCGCCCCTG TACAAGAATG TAGCACACAG CTTGACATAG TCATCGTCCT AGATGGCTCC 
AACAGCATCT ACCCCTGGGA AAGTGTCACT GCCTTTTTAA ACGACCTTCT TAAGAGGATG 
GACATTGGCC CCAAACAGAC ACAGGTTGGA ATTGTACAAT ATGGAGCAAA TGTAACACAT 
GAGTTCAACC TCAATAAGTA TTCATCCACA GAAGAGGTCC TGGTGGCAGC AAACAAAATA 
GGCCGCAGGG GTGGTCTCCA GACGATGACA GCCCTTGGAA TAGACACAGC CAGGAAAGAG 
GCATTCACTG AAGCTCGGGG GGCCAGAAGG GGAGTGAAAA AAGTCATGGT TATTGTGACT 
GATGGAGAAT CGCATGACAA CTATCGCCTG AAACAGGTCA TCCAAGACTG TGAGGATGAA 
AACATTCAGC GATTTTCCAT AGCTATCCTT GGCCACTATA ACAGGGGGAA CTTAAGCACC 
GAAAAATTTG TGGAGGAGAT AAAATCAATC GCAAGTGAGC CCACCGAAAA GCACTTCTTC 
AACGTCTCAG ATGAGTTGGC CCTGGTCACT ATTGTTAAAG CTCTGGGAGA AAGGATATTT 
GCTTTGGAAG CTACAGCTGA CCAGTCAGCA GCTTCGTTTG AAATGGAGAT GTCTCAGACC 
GGCTTCAGTG CTCATTATTC ACAGGACTGG GTCATGCTTG GAGCTGTTGG AGCCTATGAC 
TGGAACGGAA CTGTGGTCAT GCAGAAGGCT AACCAGATTG TCATCCCTCA TAACACCACC 
TTTCAAACTG AGCCCACCAA GATGAACGAG CCTCTTGCTT CTTACTTGGG TTACACAGTG 
AACTCTGCCA CCATCCCGGG AGATGTGCTC TATATCGCTG GGCAGCCTCG GTACAATCAC 
ACCGGCCAGG TCGTCATCTA CAAGATGGAG GATGGGGACG TCAACATTCT GCAGACACTC 
AGTGGAGAGC AGATCGGATC CTACTTTGGT AGCGTCTTAA CCACAATTGA CATCGACAAA 
GATTCTTACA CTGATCTGCT TCTCGTCGGG GCTCCCATGT ATATGGGGAC AGAGAAAGAG 
GAACAGGGCA AGGTGTACGT GTACGCTGTG AATCAGACGA GGTTTGAATA TCAAATGAGC 
CTGGAACCAA TTAAGCAGAC CTGCTGTTCA TCCCTGAAGG ATAATTCATG CACAAAAGAA 
AACAAGAATG AGCCCTGTGG GGCCCGTTTT GGAACAGCAG TTGCTGCTGT AAAAGACCTC 
AACGTGGATG GCTTTAATGA CGTCGTGATT GGAGCTCCCC TGGAAGACGA CCACGCAGGA 
GCTGTGTACA TTTATCATGG CAGTGGCAAG ACCATAAGGA AAGAGTATGC GCAACGCATT 
CCCTCAGGTG GGGATGGGAA GACGCTGAAA TTTTTTGGCC AGTCTATCCA CGGAGAGATG 
GATTTAAATG GCGATGGTCT GACTGACGTG ACCATTGGAG GCCTTGGAGG AGCTGCCCTC 
TTCTGGGCCA GAGATGTGGC TGTAGTTAAA GTGACCATGA ATTTTGAACC CAACAAAGTG 
AATATTCAAA AGAAAAACTG CCGTGTGGAG GGCAAAGAAA CAGTATGCAT AAATGCTACA 
ATGTGTTTTC ATGTGAAATT GAAGTCTAAA GAAGACTCAG TTTACGAGGC TGATCTGCAG 
TACCGTGTCA CCCTTGATTC GCTGAGGCAG ATATCACGGA GCTTTTTTTC TGGAACTCAG 
GAAAGGAGGA TTCAAAGAAA CCTCACCGTT CGAGAATCCG AATGCATCAG GCACTCCTTC 
TACATGTTGG ATAAGCACGA CTTTCAGGAC TCCGTGAGAG TGACTTTGGA TTTTAACCTC 
ACTGATCCAG AAAATGGGCC CGTGCTCGAT GACGCTCTGC CAAACTCAGT CCATGGACAT 
ATTCCTTTTG CCAAAGACTG TGGGAACAAG GAAAGATGCG TTTCAGACCT CACCCTGGAT 
GTGTCCACAA CAGAAAAGAA CCTGCTGATT GTCAGATCCC AGAATGACAA GTTCAATGTC 
AGCCTCACCG TCAAAAACAA GGGAGACAGT GCGTACAACA CCCGGACAGT GGTTCAGTAT 
TCTCCAAATC TGATTTTTTC AGGAATTGAG GAGATCCAAA AAGATAGCTG CGAATCCAAT 
CAAAATATCA CGTGTAGAGT TGGATATCCT TTCCTGAGGA CAGGAGACGT GGTTAACTTC 
AAAATAATAT TCCAGTTTAA TACATCACAT CTCTCAGAAA ATGCAATTAT TCATTTAAGT 
GCAACAAGTG ACAGTGAAGA GCCCCTGGAA TCTCTTTACG ATAATGAAGT AAATATTTCC 
ATCCCCGTAA AATATGAAGT CGGACTGCAG TTTTACAGTT CTGCGAGTGA ACACCACATT 
TCAGTTGCTG CCAATGAGAC TGTTCCTGAG CTGATTAATT CCACCAAGGA CATTGGGGAT 
GAAATTAATG TCTTCTACAC GATTAGAAAA AGAGGGCATT TCCCAATGCC AGAACTTCGG 
CTGGCAATTT CATTTCCCAA TCTGACGTCA GATGGCTATC CTGTACTGTA CCCAACTGGA 
TGGTCATCTT CTGATAATGT AAACTGCAGA CCTCGAAGCC TTGAGGACCC TTTGGGTATC 
AACTCTGGGA AGAAAATGAC AATATCAAAG TCTGAGGTTC TCAAAAGAGG CACAATCCAG 
GACTGCAGTA CCTGCAAGAT TGCTACCATC ACGTGTCATC TCCTTCCCTC GGATGTGAGT 
CAAGTGAATG TCTCACTCAT CTTGTGGAAA CCAACTTTCA TAAAAGCACA TTTTTCCAGC 
TTAAATCTTA CCATACGGGG AGAACTTCAG AGTGAAAACT CATCGCTGAC TTTAAGCAGC 
AGCAACCGGA AACGAGAGCT GGCTATTCAG ATATCCAAAG ACGGGCTCCC AGGCCGAGTG 
CCGCTGTGGG TTATCCTCCT GAGCGCCTTT GCGGGACTCC TGCTGTTAAT GCTGCTTATA 
TTAGCTCTGT GGAAGATTGG ATTCTTCAAA AGGCCACTAA AGAAGAAAAT GGAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028400.2
CDS	434..3973
Translation	MVPRRPASLEVTVACIWLLTVILGVCISFNVDVKNSMSFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKARTGDVYKCPVGRERSMPCVKLDLPVNTSIPNVTEIKENMTFGSTLVTNPKGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSFAPVQECSTQLDIVIVLDGSNSIYPWESVTAFLNDLLKRMDIGPKQTQVGIVQYGANVTHEFNLNKYSSTEEVLVAANKIGRRGGLQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNYRLKQVIQDCEDENIQRFSIAILGHYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKALGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKANQIVIPHNTTFQTEPTKMNEPLASYLGYTVNSATIPGDVLYIAGQPRYNHTGQVVIYKMEDGDVNILQTLSGEQIGSYFGSVLTTIDIDKDSYTDLLLVGAPMYMGTEKEEQGKVYVYAVNQTRFEYQMSLEPIKQTCCSSLKDNSCTKENKNEPCGARFGTAVAAVKDLNVDGFNDVVIGAPLEDDHAGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWARDVAVVKVTMNFEPNKVNIQKKNCRVEGKETVCINATMCFHVKLKSKEDSVYEADLQYRVTLDSLRQISRSFFSGTQERRIQRNLTVRESECIRHSFYMLDKHDFQDSVRVTLDFNLTDPENGPVLDDALPNSVHGHIPFAKDCGNKERCVSDLTLDVSTTEKNLLIVRSQNDKFNVSLTVKNKGDSAYNTRTVVQYSPNLIFSGIEEIQKDSCESNQNITCRVGYPFLRTGDVVNFKIIFQFNTSHLSENAIIHLSATSDSEEPLESLYDNEVNISIPVKYEVGLQFYSSASEHHISVAANETVPELINSTKDIGDEINVFYTIRKRGHFPMPELRLAISFPNLTSDGYPVLYPTGWSSSDNVNCRPRSLEDPLGINSGKKMTISKSEVLKRGTIQDCSTCKIATITCHLLPSDVSQVNVSLILWKPTFIKAHFSSLNLTIRGELQSENSSLTLSSSNRKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK

Target ORF information:

RefSeq Version	NM_001033228.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus integrin alpha 1 (Itga1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033228.3

ORF Insert Sequence:

ATGGTCCCCA GGCGTCCTGC TAGCCTAGAG GTCACTGTAG CCTGCATCTG GCTTCTCACC 
GTTATCCTAG GCGTCTGCAT CTCCTTCAAC GTTGATGTCA AAAACTCCAT GAGCTTCAGT 
GGTCCAGTGG AGGACATGTT TGGATACACC GTTCAACAGT ATGAAAACGA AGAAGGCAAA 
TGGGTTCTTA TTGGTTCTCC TTTAGTTGGC CAACCCAAAG CAAGAACTGG AGATGTCTAT 
AAGTGTCCAG TTGGGAGAGA GAGATCAATG CCTTGTGTGA AGTTGGATTT ACCAGTTAAC 
ACATCGATTC CTAATGTCAC AGAAATAAAG GAAAACATGA CATTTGGATC AACTTTAGTC 
ACCAATCCGA AGGGAGGATT TCTGGCATGT GGGCCCTTGT ATGCCTATAG ATGTGGACAT 
TTGCATTATA CGACTGGCAT ATGTTCTGAT GTCAGCCCTA CATTTCAAGT TGTGAACTCG 
TTCGCCCCTG TACAAGAATG TAGCACACAG CTTGACATAG TCATCGTCCT AGATGGCTCC 
AACAGCATCT ACCCCTGGGA AAGTGTCACT GCCTTTTTAA ACGACCTTCT TAAGAGGATG 
GACATTGGCC CCAAACAGAC ACAGGTTGGA ATTGTACAAT ATGGAGCAAA TGTAACACAT 
GAGTTCAACC TCAATAAGTA TTCATCCACA GAAGAGGTCC TGGTGGCAGC AAACAAAATA 
GGCCGCAGGG GTGGTCTCCA GACGATGACA GCCCTTGGAA TAGACACAGC CAGGAAAGAG 
GCATTCACTG AAGCTCGGGG GGCCAGAAGG GGAGTGAAAA AAGTCATGGT TATTGTGACT 
GATGGAGAAT CGCATGACAA CTATCGCCTG AAACAGGTCA TCCAAGACTG TGAGGATGAA 
AACATTCAGC GATTTTCCAT AGCTATCCTT GGCCACTATA ACAGGGGGAA CTTAAGCACC 
GAAAAATTTG TGGAGGAGAT AAAATCAATC GCAAGTGAGC CCACCGAAAA GCACTTCTTC 
AACGTCTCAG ATGAGTTGGC CCTGGTCACT ATTGTTAAAG CTCTGGGAGA AAGGATATTT 
GCTTTGGAAG CTACAGCTGA CCAGTCAGCA GCTTCGTTTG AAATGGAGAT GTCTCAGACC 
GGCTTCAGTG CTCATTATTC ACAGGACTGG GTCATGCTTG GAGCTGTTGG AGCCTATGAC 
TGGAACGGAA CTGTGGTCAT GCAGAAGGCT AACCAGATTG TCATCCCTCA TAACACCACC 
TTTCAAACTG AGCCCACCAA GATGAACGAG CCTCTTGCTT CTTACTTGGG TTACACAGTG 
AACTCTGCCA CCATCCCGGG AGATGTGCTC TATATCGCTG GGCAGCCTCG GTACAATCAC 
ACCGGCCAGG TCGTCATCTA CAAGATGGAG GATGGGGACG TCAACATTCT GCAGACACTC 
AGTGGAGAGC AGATCGGATC CTACTTTGGT AGCGTCTTAA CCACAATTGA CATCGACAAA 
GATTCTTACA CTGATCTGCT TCTCGTCGGG GCTCCCATGT ATATGGGGAC AGAGAAAGAG 
GAACAGGGCA AGGTGTACGT GTACGCTGTG AATCAGACGA GGTTTGAATA TCAAATGAGC 
CTGGAACCAA TTAAGCAGAC CTGCTGTTCA TCCCTGAAGG ATAATTCATG CACAAAAGAA 
AACAAGAATG AGCCCTGTGG GGCCCGTTTT GGAACAGCAG TTGCTGCTGT AAAAGACCTC 
AACGTGGATG GCTTTAATGA CGTCGTGATT GGAGCTCCCC TGGAAGACGA CCACGCAGGA 
GCTGTGTACA TTTATCATGG CAGTGGCAAG ACCATAAGGA AAGAGTATGC GCAACGCATT 
CCCTCAGGTG GGGATGGGAA GACGCTGAAA TTTTTTGGCC AGTCTATCCA CGGAGAGATG 
GATTTAAATG GCGATGGTCT GACTGACGTG ACCATTGGAG GCCTTGGAGG AGCTGCCCTC 
TTCTGGGCCA GAGATGTGGC TGTAGTTAAA GTGACCATGA ATTTTGAACC CAACAAAGTG 
AATATTCAAA AGAAAAACTG CCGTGTGGAG GGCAAAGAAA CAGTATGCAT AAATGCTACA 
ATGTGTTTTC ATGTGAAATT GAAGTCTAAA GAAGACTCAG TTTACGAGGC TGATCTGCAG 
TACCGTGTCA CCCTTGATTC GCTGAGGCAG ATATCACGGA GCTTTTTTTC TGGAACTCAG 
GAAAGGAGGA TTCAAAGAAA CCTCACCGTT CGAGAATCCG AATGCATCAG GCACTCCTTC 
TACATGTTGG ATAAGCACGA CTTTCAGGAC TCCGTGAGAG TGACTTTGGA TTTTAACCTC 
ACTGATCCAG AAAATGGGCC CGTGCTCGAT GACGCTCTGC CAAACTCAGT CCATGGACAT 
ATTCCTTTTG CCAAAGACTG TGGGAACAAG GAAAGATGCG TTTCAGACCT CACCCTGGAT 
GTGTCCACAA CAGAAAAGAA CCTGCTGATT GTCAGATCCC AGAATGACAA GTTCAATGTC 
AGCCTCACCG TCAAAAACAA GGGAGACAGT GCGTACAACA CCCGGACAGT GGTTCAGTAT 
TCTCCAAATC TGATTTTTTC AGGAATTGAG GAGATCCAAA AAGATAGCTG CGAATCCAAT 
CAAAATATCA CGTGTAGAGT TGGATATCCT TTCCTGAGGA CAGGAGACGT GGTTAACTTC 
AAAATAATAT TCCAGTTTAA TACATCACAT CTCTCAGAAA ATGCAATTAT TCATTTAAGT 
GCAACAAGTG ACAGTGAAGA GCCCCTGGAA TCTCTTTACG ATAATGAAGT AAATATTTCC 
ATCCCCGTAA AATATGAAGT CGGACTGCAG TTTTACAGTT CTGCGAGTGA ACACCACATT 
TCAGTTGCTG CCAATGAGAC TGTTCCTGAG CTGATTAATT CCACCAAGGA CATTGGGGAT 
GAAATTAATG TCTTCTACAC GATTAGAAAA AGAGGGCATT TCCCAATGCC AGAACTTCGG 
CTGGCAATTT CATTTCCCAA TCTGACGTCA GATGGCTATC CTGTACTGTA CCCAACTGGA 
TGGTCATCTT CTGATAATGT AAACTGCAGA CCTCGAAGCC TTGAGGACCC TTTGGGTATC 
AACTCTGGGA AGAAAATGAC AATATCAAAG TCTGAGGTTC TCAAAAGAGG CACAATCCAG 
GACTGCAGTA CCTGCAAGAT TGCTACCATC ACGTGTCATC TCCTTCCCTC GGATGTGAGT 
CAAGTGAATG TCTCACTCAT CTTGTGGAAA CCAACTTTCA TAAAAGCACA TTTTTCCAGC 
TTAAATCTTA CCATACGGGG AGAACTTCAG AGTGAAAACT CATCGCTGAC TTTAAGCAGC 
AGCAACCGGA AACGAGAGCT GGCTATTCAG ATATCCAAAG ACGGGCTCCC AGGCCGAGTG 
CCGCTGTGGG TTATCCTCCT GAGCGCCTTT GCGGGACTCC TGCTGTTAAT GCTGCTTATA 
TTAGCTCTGT GGAAGATTGG ATTCTTCAAA AGGCCACTAA AGAAGAAAAT GGAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Semaphorin7A aggravates coxsackievirusB3-induced viral myocarditis by increasing ?1?1-integrin macrophages and subsequent enhanced inflammatory response.
Journal of molecular and cellular cardiology11448-57(2017 Nov)
Wu X,Meng Y,Wang C,Yue Y,Dong C,Xiong S

Cross-talk of SFRP4, integrin ?1?1, and Notch1 inhibits cardiac differentiation of P19CL6 cells.
Cellular signalling28(11)1806-15(2016 Nov)
Tian Y,Wang W,Lu Q,Chen P,Ma K,Jia Z,Zhou C

Langerhans Cells Suppress CD49a+ NK Cell-Mediated Skin Inflammation.
Journal of immunology (Baltimore, Md. : 1950)195(5)2335-42(2015 Sep)
Scholz F,Naik S,Sutterwala FS,Kaplan DH

Integrin ?1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance.
The Journal of biological chemistry290(10)6546-57(2015 Mar)
Williams AS,Kang L,Zheng J,Grueter C,Bracy DP,James FD,Pozzi A,Wasserman DH

Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice.
PloS one10(9)e0137797(2015)
Wang H,Shun MC,Dickson AK,Engelman AN

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Itga1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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