Pkn2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pkn2
Entrez Gene ID	109333
Full Name	protein kinase N2
Synonyms	6030436C20Rik,AI507382,PRK2,Prkcl2,Stk7
General protein information	Preferred Names protein kinase N2 Names serine/threonine-protein kinase N2 PKN gamma protein kinase C-like 2 protein-kinase C-related kinase 2 serine/threonine kinase 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 H1\|3 66.69 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_178654.4	NP_848769.2	serine/threonine-protein kinase N2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PKN2	XP_001145367.1
	LOC693505	XP_002808270.1
Gallus gallus (chicken)	PKN2	XP_422357.3
Drosophila melanogaster (fruit fly)	Pkn	NP_788292.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007587	XP_308283.5
Xenopus tropicalis (tropical clawed frog)	pkn2	XP_004913783.1
Mus musculus (house mouse)	Pkn2	NP_848769.2
Canis lupus familiaris (dog)	PKN2	XP_547295.4
Homo sapiens (human)	PKN2	NP_006247.1
Bos taurus (cattle)	PKN2	NP_001180171.1
Rattus norvegicus (Norway rat)	Pkn2	NP_001099225.2
Danio rerio (zebrafish)	pkn2	XP_700704.3
Caenorhabditis elegans (roundworm)	pkn-1	NP_001257102.1

Gene Ontology
Bibliography

Related articles in PubMed

The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression.
Yang CS, Melhuish TA, Spencer A, Ni L, Hao Y, Jividen K, Harris TE, Snow C, Frierson HF Jr, Wotton D, Paschal BM
The Prostate77(15)1452-1467(2017 Nov)

Protein kinase N2 regulates AMP kinase signaling and insulin responsiveness of glucose metabolism in skeletal muscle.
Ruby MA, Riedl I, Massart J, ?hlin M, Zierath JR
American journal of physiology. Endocrinology and metabolism313(4)E483-E491(2017 Oct)

PKN2 is essential for mouse embryonic development and proliferation of mouse fibroblasts.
Danno S, Kubouchi K, Mehruba M, Abe M, Natsume R, Sakimura K, Eguchi S, Oka M, Hirashima M, Yasuda H, Mukai H
Genes to cells : devoted to molecular & cellular mechanisms22(2)220-236(2017 Feb)

PKN2 and Cdo interact to activate AKT and promote myoblast differentiation.
Lee SJ, Hwang J, Jeong HJ, Yoo M, Go GY, Lee JR, Leem YE, Park JW, Seo DW, Kim YK, Hahn MJ, Han JW, Kang JS, Bae GU
Cell death & disease7(10)e2431(2016 Oct)

The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome.
Chung LK, Park YH, Zheng Y, Brodsky IE, Hearing P, Kastner DL, Chae JJ, Bliska JB
Cell host & microbe20(3)296-306(2016 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In mature skeletal muscle, in vivo PKN2 knockdown decreased glucose uptake and increased AMPK phosphorylation. Thus, PKN2 alters key signaling pathways and transcriptional networks to regulate glucose and lipid metabolism.
Title: Protein kinase N2 regulates AMP kinase signaling and insulin responsiveness of glucose metabolism in skeletal muscle.

To unravel the in vivo physiological function of PKN2, we targeted the PKN2 gene. Constitutive disruption of the mouse PKN2 gene resulted in growth retardation and lethality before embryonic day (E) 10.5. PKN2(-/-) embryo did not undergo axial turning and showed insufficient closure of the neural tube.Mouse embryonic fibroblasts (MEFs) derived from PKN2(-/-) embryos at E9.5 failed to grow.
Title: PKN2 is essential for mouse embryonic development and proliferation of mouse fibroblasts.

PKN2 formed complexes with Cdo, APPL1 and AKT via its C-terminal region and this interaction appeared to be important for induction of AKT activity as well as myoblast differentiation.
Title: PKN2 and Cdo interact to activate AKT and promote myoblast differentiation.

Mechanistically, Yersinia pseudotuberculosis YopM recruits and activates the mouse host kinases PRK1 and PRK2 to negatively regulate pyrin by phosphorylation.
Title: The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome.

Yersinia pseudotuberculosis mutants expressing YopM proteins unable to interact with either RSK1 or PRK2 were defective for virulence in this assay, indicating that both interaction domains are important for YopM to promote pathogenesis.
Title: Delineation of regions of the Yersinia YopM protein required for interaction with the RSK1 and PRK2 host kinases and their requirement for interleukin-10 production and virulence.

The following Pkn2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pkn2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15373	NM_178654.4 Latest version!	Mus musculus protein kinase N2 (Pkn2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$580.30 $829.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pkn2 ( NM_178654.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_848769.2 Mus musculus protein kinase N2 (Pkn2), mRNA.

Price & Availability↑

CloneID	OMu15373
Clone ID Related Accession (Same CDS sequence)	NM_178654.4
Accession Version	NM_178654.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2952bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase N2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY729073.1, AK133298.1, AK049713.1 and AK140746.1. On Sep 30, 2009 this sequence version replaced NM_178654.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK133298.1, AK171092.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCGTCCA ACCCCGACCG GGGGGAGATC CTCCTCACCG AGCTGCAGGG AGATTCCCGG 
ACTCTTCCAT TTTCTGAGAA TGTGAGTGCT GTTCAGAAAT TAGACTTTTC AGATACAATG 
GTGCAACAGA AATTGGACGA CATCAAGGAT CGAATAAAGA GAGAAATAAG GAAAGAACTG 
AAAATCAAAG AAGGAGCTGA AAACCTGAGG AAAGTTACAA CAGATAAGAA AAATTTGGCT 
TATGTAGACA ACATTTTGAA AAAATCAAAT AAAAAATTAG AAGAATTACA TCACAAGCTA 
CAAGAATTAA ATGCACACAT CGTTGTATCG GATCCAGAGG ACTCCACAGA TTGTCCGAGG 
ACTCCAGATA CTCCAAATAG TGACTCTCGT AGTTCTACTA GCAACAATAG ACTGATGGCC 
TTACAGAAAC AACTGGATAT AGAACTTAAA GTAAAGCAGG GTGCAGAGAA CATGATACAG 
ATGTACTCAA ATGGCTCTTC AAAGGATCGG AAACTCCATG GTACAGCGCA GCAACTGCTA 
CAGGATAGCA AGACAAAAAT AGAAGTCATC CGGATGCAGA TTCTTCAGGC CGTCCAGACC 
AATGAGCTGG CTTTTGATAA TGCAAAACCT GTGATAAGCC CTCTTGAGCT TCGGATGGAA 
GAATTAAGAC ATCATTTTAA GATAGAATTT GCAGTAGCCG AAGGTGCAAA GAATGTCATG 
AAGTTACTTG GCTCAGGAAA AGTAACAGAC AGAAAAGCGC TTTCAGAAGC ACAAGCGAGA 
TTTAATGAAT CAAGTCAGAA GTTGGACCTT TTAAAGTATT CACTAGAGCA AAGGTTAAAT 
GAGCTCCCCA GGAATCACCC CAAAAGCAGT GTCGTCATTG AGGAGCTTTC ACTGGTTGCG 
TCACCAACCC TGAGTCCACG GCAGAGCATG CTGTCCACGC AGAACCAGTA TAGCACACTG 
TCCAAGCCAG CGGCGCTAAC CGGTACTTTG GAAGTTCGTC TTATGGGGTG CCAAGATATC 
CTAGAGAATG TACCTGGACG GTCAAAAGCA ACGTCGGTAG CACTACCTGG GTGGAGTCCA 
AGTGACAACA GATCGTCTTT TATGAGCAGA ACCAGCAAGA GTAAAAGTGG GAGTAGTCGC 
AACCTCCTGA AAACGGATGA CTTGTCCAAT GATGTTTGTG CTGTTTTGAA GCTAGATAAT 
ACTGTGGTTG GTCAAACTAG CTGGAAACCC ATTTCAAATC AGTCGTGGGA CCAGAAGTTT 
ACACTGGAAC TAGACAGGTC ACGTGAACTG GAAATTTCAG TTTATTGGCG TGATTGGCGA 
TCTCTGTGTG CTGTAAAATT TCTGAGGTTA GAAGATTTTT TAGACAACCA GCGGCATGGC 
ATGTGTCTCT ATTTGGAACC ACAGGGTACT TTGTTTGCAG AGGTTACTTT TTTTAATCCA 
GTTATTGAAA GACGACCAAA ACTCCAAAGA CAAAAGAAAA TTTTTTCAAA ACAACAAGGC 
AAAACATTTC TCAGAGCTCC TCAGATGAAT ATTAATATTG CCACTTGGGG AAGACTAGTG 
AGACGAGCTA TTCCCACAGT AAATCATTCT GGCACATTCA GCCCTCAGAC TCCTGTGCCT 
GCAACAGTGC CAGTCGTTGA CGCACGCATT CCTGATCTAG CACCTCCGGC CAGTGACTCT 
ACAGTAACCA AATTGGACTT TGATCTTGAA CCTGAACCTC CTCCAGCCCC ACCTCGTGCT 
TCTTCCCTTG GAGAGACAGA TGAATCTTCT GAATTGAGAG TTTTGGATAT ACCTGGACAG 
GGTTCAGAAA CTGTTTTCAA TATTGAGAAT GACAGAAATA ACCTGCGTCC AAAATCCAAA 
TCTGAATATG AGCTGAGCAT TCCTGACTCA GGTCGAAGCT GCTGGGGTGT TGGAGAGCTT 
GATGACAAGA GAGCTCAGCA GAGGTTTCAG TTCAGTCTAC AGGACTTCAG GTGCTGTGCT 
GTCTTGGGGA GAGGACACTT TGGAAAGGTG CTGTTGGCGG AATATAAACA CACAAATGAA 
ATGTTTGCAA TAAAAGCCTT AAAGAAAGGA GACATTGTGG CACGAGATGA AGTAGACAGC 
CTGATGTGTG AAAAAAGAAT TTTTGAGACT GTGAATAGTG TCAGGCACCC GTTTCTAGTG 
AACCTTTTTG CATGTTTCCA AACAAAAGAA CATGTTTGCT TCGTGATGGA GTATGCTGCA 
GGTGGTGACC TGATGATGCA CATCCATACT GATGTCTTCT CTGAACCCAG AGCTGTATTT 
TATGCAGCAT GTGTAGTTCT TGGGTTGCAA TACTTACATG AACACAAAAT TGTTTATAGA 
GATTTGAAGT TGGATAACTT GTTGCTAGAT ACAGAAGGCT TTGTGAAAAT TGCTGACTTT 
GGTCTTTGCA AAGAAGGAAT GGGGTATGGA GATAGGACAA GCACATTTTG TGGTACTCCT 
GAGTTTCTTG CCCCAGAAGT CCTAACAGAA ACATCGTACA CAAGGGCTGT AGATTGGTGG 
GGCCTTGGTG TACTTATATA TGAGATGCTC GTCGGCGAGT CTCCCTTTCC TGGTGATGAT 
GAAGAAGAGG TTTTTGACAG TATTGTAAAT GACGAAGTAA GGTATCCAAG GTTCTTATCT 
ACAGAAGCCA TTTCCATAAT GAGAAGGCTG CTAAGGAGAA ATCCTGAGCG GCGCCTGGGA 
GCTGGTGAGA AGGATGCAGA GGATGTCAAG AAGCACCCGT TTTTCCGGCT AACCGACTGG 
AGTGCTCTAA TGGACAAAAA AGTAAAGCCA CCATTTGTAC CTACCATTAG AGGACGGGAA 
GATGTTAGTA ACTTTGATGA TGAATTTACC TCAGAAGCAC CTATTCTGAC TCCACCTCGA 
GAACCAAGGA TACTCTTGGA AGAGGAGCAG GAGATGTTCC ACGATTTTGA CTACGTTGCT 
GATTGGTGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848769.2
CDS	347..3298
Translation	MASNPDRGEILLTELQGDSRTLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKNLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDSTDCPRTPDTPNSDSRSSTSNNRLMALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFKIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPRNHPKSSVVIEELSLVASPTLSPRQSMLSTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSDNRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQTPVPATVPVVDARIPDLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGETDESSELRVLDIPGQGSETVFNIENDRNNLRPKSKSEYELSIPDSGRSCWGVGELDDKRAQQRFQFSLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQEMFHDFDYVADWC

Target ORF information:

RefSeq Version	NM_178654.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase N2 (Pkn2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178654.4

ORF Insert Sequence:

ATGGCGTCCA ACCCCGACCG GGGGGAGATC CTCCTCACCG AGCTGCAGGG AGATTCCCGG 
ACTCTTCCAT TTTCTGAGAA TGTGAGTGCT GTTCAGAAAT TAGACTTTTC AGATACAATG 
GTGCAACAGA AATTGGACGA CATCAAGGAT CGAATAAAGA GAGAAATAAG GAAAGAACTG 
AAAATCAAAG AAGGAGCTGA AAACCTGAGG AAAGTTACAA CAGATAAGAA AAATTTGGCT 
TATGTAGACA ACATTTTGAA AAAATCAAAT AAAAAATTAG AAGAATTACA TCACAAGCTA 
CAAGAATTAA ATGCACACAT CGTTGTATCG GATCCAGAGG ACTCCACAGA TTGTCCGAGG 
ACTCCAGATA CTCCAAATAG TGACTCTCGT AGTTCTACTA GCAACAATAG ACTGATGGCC 
TTACAGAAAC AACTGGATAT AGAACTTAAA GTAAAGCAGG GTGCAGAGAA CATGATACAG 
ATGTACTCAA ATGGCTCTTC AAAGGATCGG AAACTCCATG GTACAGCGCA GCAACTGCTA 
CAGGATAGCA AGACAAAAAT AGAAGTCATC CGGATGCAGA TTCTTCAGGC CGTCCAGACC 
AATGAGCTGG CTTTTGATAA TGCAAAACCT GTGATAAGCC CTCTTGAGCT TCGGATGGAA 
GAATTAAGAC ATCATTTTAA GATAGAATTT GCAGTAGCCG AAGGTGCAAA GAATGTCATG 
AAGTTACTTG GCTCAGGAAA AGTAACAGAC AGAAAAGCGC TTTCAGAAGC ACAAGCGAGA 
TTTAATGAAT CAAGTCAGAA GTTGGACCTT TTAAAGTATT CACTAGAGCA AAGGTTAAAT 
GAGCTCCCCA GGAATCACCC CAAAAGCAGT GTCGTCATTG AGGAGCTTTC ACTGGTTGCG 
TCACCAACCC TGAGTCCACG GCAGAGCATG CTGTCCACGC AGAACCAGTA TAGCACACTG 
TCCAAGCCAG CGGCGCTAAC CGGTACTTTG GAAGTTCGTC TTATGGGGTG CCAAGATATC 
CTAGAGAATG TACCTGGACG GTCAAAAGCA ACGTCGGTAG CACTACCTGG GTGGAGTCCA 
AGTGACAACA GATCGTCTTT TATGAGCAGA ACCAGCAAGA GTAAAAGTGG GAGTAGTCGC 
AACCTCCTGA AAACGGATGA CTTGTCCAAT GATGTTTGTG CTGTTTTGAA GCTAGATAAT 
ACTGTGGTTG GTCAAACTAG CTGGAAACCC ATTTCAAATC AGTCGTGGGA CCAGAAGTTT 
ACACTGGAAC TAGACAGGTC ACGTGAACTG GAAATTTCAG TTTATTGGCG TGATTGGCGA 
TCTCTGTGTG CTGTAAAATT TCTGAGGTTA GAAGATTTTT TAGACAACCA GCGGCATGGC 
ATGTGTCTCT ATTTGGAACC ACAGGGTACT TTGTTTGCAG AGGTTACTTT TTTTAATCCA 
GTTATTGAAA GACGACCAAA ACTCCAAAGA CAAAAGAAAA TTTTTTCAAA ACAACAAGGC 
AAAACATTTC TCAGAGCTCC TCAGATGAAT ATTAATATTG CCACTTGGGG AAGACTAGTG 
AGACGAGCTA TTCCCACAGT AAATCATTCT GGCACATTCA GCCCTCAGAC TCCTGTGCCT 
GCAACAGTGC CAGTCGTTGA CGCACGCATT CCTGATCTAG CACCTCCGGC CAGTGACTCT 
ACAGTAACCA AATTGGACTT TGATCTTGAA CCTGAACCTC CTCCAGCCCC ACCTCGTGCT 
TCTTCCCTTG GAGAGACAGA TGAATCTTCT GAATTGAGAG TTTTGGATAT ACCTGGACAG 
GGTTCAGAAA CTGTTTTCAA TATTGAGAAT GACAGAAATA ACCTGCGTCC AAAATCCAAA 
TCTGAATATG AGCTGAGCAT TCCTGACTCA GGTCGAAGCT GCTGGGGTGT TGGAGAGCTT 
GATGACAAGA GAGCTCAGCA GAGGTTTCAG TTCAGTCTAC AGGACTTCAG GTGCTGTGCT 
GTCTTGGGGA GAGGACACTT TGGAAAGGTG CTGTTGGCGG AATATAAACA CACAAATGAA 
ATGTTTGCAA TAAAAGCCTT AAAGAAAGGA GACATTGTGG CACGAGATGA AGTAGACAGC 
CTGATGTGTG AAAAAAGAAT TTTTGAGACT GTGAATAGTG TCAGGCACCC GTTTCTAGTG 
AACCTTTTTG CATGTTTCCA AACAAAAGAA CATGTTTGCT TCGTGATGGA GTATGCTGCA 
GGTGGTGACC TGATGATGCA CATCCATACT GATGTCTTCT CTGAACCCAG AGCTGTATTT 
TATGCAGCAT GTGTAGTTCT TGGGTTGCAA TACTTACATG AACACAAAAT TGTTTATAGA 
GATTTGAAGT TGGATAACTT GTTGCTAGAT ACAGAAGGCT TTGTGAAAAT TGCTGACTTT 
GGTCTTTGCA AAGAAGGAAT GGGGTATGGA GATAGGACAA GCACATTTTG TGGTACTCCT 
GAGTTTCTTG CCCCAGAAGT CCTAACAGAA ACATCGTACA CAAGGGCTGT AGATTGGTGG 
GGCCTTGGTG TACTTATATA TGAGATGCTC GTCGGCGAGT CTCCCTTTCC TGGTGATGAT 
GAAGAAGAGG TTTTTGACAG TATTGTAAAT GACGAAGTAA GGTATCCAAG GTTCTTATCT 
ACAGAAGCCA TTTCCATAAT GAGAAGGCTG CTAAGGAGAA ATCCTGAGCG GCGCCTGGGA 
GCTGGTGAGA AGGATGCAGA GGATGTCAAG AAGCACCCGT TTTTCCGGCT AACCGACTGG 
AGTGCTCTAA TGGACAAAAA AGTAAAGCCA CCATTTGTAC CTACCATTAG AGGACGGGAA 
GATGTTAGTA ACTTTGATGA TGAATTTACC TCAGAAGCAC CTATTCTGAC TCCACCTCGA 
GAACCAAGGA TACTCTTGGA AGAGGAGCAG GAGATGTTCC ACGATTTTGA CTACGTTGCT 
GATTGGTGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression.
The Prostate77(15)1452-1467(2017 Nov)
Yang CS,Melhuish TA,Spencer A,Ni L,Hao Y,Jividen K,Harris TE,Snow C,Frierson HF Jr,Wotton D,Paschal BM

Protein kinase N2 regulates AMP kinase signaling and insulin responsiveness of glucose metabolism in skeletal muscle.
American journal of physiology. Endocrinology and metabolism313(4)E483-E491(2017 Oct)
Ruby MA,Riedl I,Massart J,?hlin M,Zierath JR

PKN2 is essential for mouse embryonic development and proliferation of mouse fibroblasts.
Genes to cells : devoted to molecular & cellular mechanisms22(2)220-236(2017 Feb)
Danno S,Kubouchi K,Mehruba M,Abe M,Natsume R,Sakimura K,Eguchi S,Oka M,Hirashima M,Yasuda H,Mukai H

PKN2 and Cdo interact to activate AKT and promote myoblast differentiation.
Cell death & disease7(10)e2431(2016 Oct)
Lee SJ,Hwang J,Jeong HJ,Yoo M,Go GY,Lee JR,Leem YE,Park JW,Seo DW,Kim YK,Hahn MJ,Han JW,Kang JS,Bae GU

The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome.
Cell host & microbe20(3)296-306(2016 Sep)
Chung LK,Park YH,Zheng Y,Brodsky IE,Hearing P,Kastner DL,Chae JJ,Bliska JB