Prex2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prex2
Entrez Gene ID	109294
Full Name	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms	6230420N16Rik,AI316880,AI553603,C030045D06Rik,D430013K02,Depdc2,P-Rex2
General protein information	Preferred Names phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 Names phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein DEP domain containing 2 DEP domain-containing protein 2 ptdIns(3,4,5)-dependent Rac exchanger 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 A2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033636.4	NP_001028808.1	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform 2
XM_006495441.4	XP_006495504.1	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1
NM_029525.1	NP_083801.1	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform 1
XM_006495441.3	XP_006495504.1	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1

Pathways from BioSystems

Homologies

	PREX2	XP_002805414.1
Danio rerio (zebrafish)	si:ch211-278g15.1	XP_001923357.1
Homo sapiens (human)	PREX2	NP_079146.2
Mus musculus (house mouse)	Prex2	NP_083801.1
Gallus gallus (chicken)	PREX2	XP_418285.3
Bos taurus (cattle)	PREX2	NP_001179455.1
Xenopus tropicalis (tropical clawed frog)	prex2	XP_002935360.2
Canis lupus familiaris (dog)	PREX2	XP_544113.3
Rattus norvegicus (Norway rat)	Prex2	NP_001101369.1
Pan troglodytes (chimpanzee)	PREX2	XP_519798.3

Gene Ontology
Bibliography

Related articles in PubMed

Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma.
Lissanu Deribe Y
Small GTPases7(3)178-85(2016 Jul)

Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Lissanu Deribe Y, Shi Y, Rai K, Nezi L, Amin SB, Wu CC, Akdemir KC, Mahdavi M, Peng Q, Chang QE, Hornigold K, Arold ST, Welch HC, Garraway LA, Chin L
Proceedings of the National Academy of Sciences of the United States of America113(9)E1296-305(2016 Mar)

PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.
Mense SM, Barrows D, Hodakoski C, Steinbach N, Schoenfeld D, Su W, Hopkins BD, Su T, Fine B, Hibshoosh H, Parsons R
Science signaling8(370)ra32(2015 Mar)

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.
Pan D, Amison RT, Riffo-Vasquez Y, Spina D, Cleary SJ, Wakelam MJ, Page CP, Pitchford SC, Welch HC
Blood125(7)1146-58(2015 Feb)

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.
Damoulakis G, Gambardella L, Rossman KL, Lawson CD, Anderson KE, Fukui Y, Welch HC, Der CJ, Stephens LR, Hawkins PT
Journal of cell science127(Pt 11)2589-600(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

complex signaling mechanisms that involve PREX2, PI3K/AKT/PTEN and downstream epigenetic machinery to deregulate expression of key cell cycle regulators
Title: Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma.

P-REX2 PH-domain-mediated inhibition of PTEN has a role in regulating insulin sensitivity and glucose homeostasis
Title: Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis.

This study demonistrated that the P-Rex2, a GEF that specifically activates Rac small GTPases, is expressed in a cell- and synapse-specific manner in the retina.
Title: P-Rex2, a Rac-guanine nucleotide exchange factor, is expressed selectively in ribbon synaptic terminals of the mouse retina.

PI3K/P-Rex/Rac pathway is required for late phase long-term potentiation in the mouse cerebellum
Title: Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase.

P-Rex1 and P-Rex2 are important regulators of Purkinje cell morphology and cerebellar function
Title: P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.

The following Prex2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prex2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu14219	NM_001033636.4 Latest version!	Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu27099	XM_006495441.4 Latest version!	Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
OMu14243	NM_029525.1 Latest version!	Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
View Old Accession Versions >>
OMu27099	XM_006495441.3	Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prex2 ( NM_001033636.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028808.1 Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu14219
Clone ID Related Accession (Same CDS sequence)	NM_001033636.4
Accession Version	NM_001033636.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK136059.1, AC164600.5 and AI553603.1. On Apr 18, 2008 this sequence version replaced NM_001033636.3. Transcript Variant: This variant (2) uses a different segment for its 5' UTR and lacks much of the 5' coding region when compared to variant 1. The resulting protein (isoform 2) is much shorter when it is compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK136059.1, CO802244.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374 [ECO:0000348] ##Evidence-Data-END##

ATGAAGCCTC TCAATGCTTT AGATGAACTT TACCGGCTGA TCACCTCATT TATCAGATCC 
AAACGCATCG CTGCCTGTGT GAACACACCT TGCAGCGCCT CTGGAGTCGG ACTGCTGTCA 
GTTTCTTCAG AGCTGTGTGA CAGGCTCGGT GCCTGTCACA TCATCATGTG CAGCAGTGGT 
GTGCACCGGT GCACCCTGAG TGTGACACTA GAGCAAACCA TCACTTTAGC AAGAAGCCAT 
GGGCTCCCTC CTCGGTACAT TATGCAGGCC ATGGATGTGA TGAGAAAGCA GGGTGCAAGA 
GTTCAGAACA CAGCTAAAAA CTTGGGCGTT AGAGACCGGA CTCCTCAGTC AGCTCCAAGG 
CTGTACAAGC TCTGCGAGCC ACCACCTCCA GTAGGAGAAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028808.1
CDS	204..608
Translation	MKPLNALDELYRLITSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQTITLARSHGLPPRYIMQAMDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGEE

Target ORF information:

RefSeq Version	NM_001033636.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033636.4

ORF Insert Sequence:

ATGAAGCCTC TCAATGCTTT AGATGAACTT TACCGGCTGA TCACCTCATT TATCAGATCC 
AAACGCATCG CTGCCTGTGT GAACACACCT TGCAGCGCCT CTGGAGTCGG ACTGCTGTCA 
GTTTCTTCAG AGCTGTGTGA CAGGCTCGGT GCCTGTCACA TCATCATGTG CAGCAGTGGT 
GTGCACCGGT GCACCCTGAG TGTGACACTA GAGCAAACCA TCACTTTAGC AAGAAGCCAT 
GGGCTCCCTC CTCGGTACAT TATGCAGGCC ATGGATGTGA TGAGAAAGCA GGGTGCAAGA 
GTTCAGAACA CAGCTAAAAA CTTGGGCGTT AGAGACCGGA CTCCTCAGTC AGCTCCAAGG 
CTGTACAAGC TCTGCGAGCC ACCACCTCCA GTAGGAGAAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prex2 ( XM_006495441.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495504.1 Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu27099
Clone ID Related Accession (Same CDS sequence)	XM_006495441.4 , XM_006495441.3
Accession Version	XM_006495441.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4854bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006495441.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC 
AGCGAGCTGC AGAAGACCGA GCGCGACTAC GTGGGCACGC TGGAGTTCCT GGTGTCGGCC 
TTCTTGCATC GAATGAACCA ATGTGCAGCA GCAAAGGTTG ATAAAAATGT GACGGAGGAA 
ACAGTGAAGA TGTTATTCTC CAATATCGAG GAGATCCTCA TCGTTCATAA GGAGTTCTTG 
AAAGTTGTAG AAGAATGCTT ATATCCGGAA CCCAGTGCTC AGCAGGAAGT GGGAGCCTGC 
TTCCTTCACT TTAAGGACAA GTTTCGTATC TATGATGAAT ATTGCAGCAA CCATGAAAAG 
GCACAAAAAT TGCTTCTTGA ACTGAACAAA ATAAGAACAA TCCGGACATT TCTTCTGAAC 
TGCATGCTGC TTGGAGGTCG GAAGAATACA GACGTTCCCC TGGAAGGATA TTTAGTGACA 
CCAATTCAGA GGATATGCAA GTACCCTCTT CTTTTGAAGG AATTACTGAA GCGGACTCCA 
CGGAGACATA GTGACTACAC AGCAGTGATG GAAGCACTCC AAGCCATGAA AGCCGTGTGT 
TCCAACATTA ATGAGGCCAA GAGACAGATG GAGAAACTGG AAGTTTTAGA AGAGTGGCAG 
GCACACATTG AAGGCTGGGA GGGGTCCAAC ATTACTGACA CCTGTACTGA GATGCTGATG 
TGTGGAGTCC TAATGAAAAT TTCTTCCGGA AATATTCAAG AACGAGTGTT TTTTCTTTTT 
GATAATCTTT TAGTATACTG CAAAAGAAAA CACAGACGGC TGAAGAATAG TAAGGCATCC 
ACAGATGGGT ATCGGTATGT CTTTCGAGGG CGGATCAATA CTGAGGTGAT GGAAGTGGAA 
AATGTGGATG ACGGCACAGC TGATTTTCAC AGCAGTGGGC ATATTGTTGT GAATGGGTGG 
AAGATACACA ACACAGCAAA AAATAAATGG TTTGTATGCA TGGCTAAAAG CCCTGAAGAA 
AAGCATGAGT GGTTTGAAGC TATTTTGAAA GAAAGAGAAC GTCGGAAAGG GTTAAAACTA 
GGAATGGAAC AAGACACCTG GGTAATGATC TCTGAGCAGG GTGAGAAATT GTATAAAATG 
ATGTGCAAAC AGGGAAATCT GATCAAAGAC AGAAAAAGAA AACTGACCAC ATTTCCTAAG 
TGCTTCCTGG GAAGTGAATT TGTCTCATGG CTATTGGAAA TTGGAGAGAT TCACAGGCCC 
GAAGAAGGTG TTCACTTAGG ACAAGCGCTG TTAGAGAATG GGATCATCCA CCATGTTACC 
GATAAGCACC AGTTCAAACC GGAGCAAATG CTATACCGAT TCCGTTATGA CGATGGTACA 
TTTTACCCCA GGAGTGAGAT GCAGGACGTG ATTTCTAAGG GTGTAAGGCT CTACTGTCGT 
CTTCATAGTC TGTTTACCCC AGTGGTCAGA GATAAAGATT ACCATTTAAG AACTTACAAA 
TCTGTTGTCA TGGCCAACAA ATTGATAGAC TGGTTAATTG CACAGGGTGA TTGCCGTACC 
AGGGAAGAGG CAATGATATT TGCTGTTGGG CTCTGTGACA ATGGATTTAT GCATCACGTC 
CTAGAAAAAA GTGAATTCAA AGATGAGCCT CTACTTTTCC GCTTTTTTGC TGATGAGGAA 
ATGGAAGGAT CAAATATGAA GCATAGGCTT ATGAAACATG ACTTGAAGGT TGTGGAGAAT 
GTCATAGCTA AGTCACTGTT GATTAAATCC AACGAAGGCA GCTATGGCTT TGGCCTAGAA 
GACAAAAACA AAGTTCCAAT AATAAAATTA GTGGAAAAGG GGTCGAATGC CGAGATGGCT 
GGCATGGAAG TTGGGAAGAA GATATTTGCC ATTAATGGTG ACCTTGTTTT TCTGAGACCT 
TTTCCTGAAG TCGATTGCTT CCTGAAATCG TGCTTAAACA GCAGAAAGCC ACTGAGAGTC 
CTCGTGAGCA CAAAGCCAAG AGAGACCGTT AAGATTCCAG ATTCTGCAGA CGGGCTTGGT 
TTCCAGATCA GAGGCTTTGG ACCTTCAGTT GTGCATGCGG TGGGAAGAGG TACTGTGGCT 
GCAGCAGCTG GCCTTCATCC AGGACAGTGT ATTATCAAAG TGAATGGAAT CAATGTCAGC 
AAAGAGACAC ATGCCAGTGT CATCGCACAT GTCACAGCCT GCCGGAAATA CAAACGGCCA 
ATGAAGCAAG ATTCCATACA GTGGGTCTAC GACAGTCTTG AAAGTGCTCA GGAAGACATT 
CAGAAGTCCC ACTCAAAGCC CCCTGGAGAC GGGGCTGGAG ATGCTTTTGA GTGCAAAGTA 
GAAGATGTCA TTGACAAGTT CAACACCATG GCTATTATTG ATGGCAAGAA GGAGCATGTG 
AGTCTGACGG TGGACAACGT CCACCTCGAG TATGGGGTTG TATATGAGTA TGATAGCACG 
GCGGGCACAA AGTGCAATGT GGTGGAGAAG ATGGTGGAGC CCAAAGGGTT CTTCAGCCTA 
ACTGCCAAGA TTCTGGAAGC CCTAGCAAAA AGTGACGAAC ATTTTGTCCA AAACTGCACC 
AGCCTTAATT CTCTGAATGA AGTGATCGCC ACTGATCTTC AGAGTAAATT CACCAGCATG 
TGCAGTGAGA GAATCGAACA TGTGTGTCAC AGAATATCCA GCTATGGGAG GTTCTCTCGG 
GTGCTGAAGA ACAGAGCCTG GCCCACCTTT AAGCAGGCCA AACCTAAGAT CTCCCCACTG 
CACAGCAGTG ATTTCTGCCC AACCAACTGC CACGTCAATG TGATGGAAGT TTCTTATCCG 
AAAACATCAA CTTCCCTGGG GAGTGCCTTC GGTGTGCAGC TAGATAGCAG AAAACATAAT 
TCTCACGATA AAGAAAATAA ATCTGTCGAG CCAGGGAAAC TGAGCCCCAT GGTGTATATT 
CAGCACACAA TCACAACCAT GGCAGCGCCT TCGGGCCTGT CACTGGGACA CAAGGATGGG 
CATGGCCTCC AGTATTTGCT GAAAGAAGAA GACTTAGAAA CTCAAGATAT CTATCACAAA 
CTTCTGGGCA AGCTGCAGAC TGCACTGAAG GAGGTAGAGA TGAGCGTTTG TCAAATTGAT 
GACCTTCTGT CTTCAATAAC ATATTCTCCT AAATTGGAAC GTAAGACAAC AGAGTGTGTG 
ACACCAATGG ACAGTGACAA CGAGAAGGGA GAGAGAAATA GCAAACGTGT CTGTTTTAAT 
GTAGCAGGGG ATGAGCAAGA GGATTCAGGC CATGATACAG TCAGCAACAG AGACTCTTAC 
AGTGGAATAC CAACCTGGGC AAGCATGTTC TTAAAGCAAC ATAAGGCTCT TTTTTGCAGT 
GACTGCAACA GCAACAGGAA TTCCATTGCT TCCTTCACGA GTATCTGCAG CAGCCAGTGC 
AGTTCCTACT TCCACAGTGA TGAGATGGAC TCAGGTGATG AGCTTCCTAT CAGTGTCCGG 
ATATCTCATG ATAAACAAGA CAAGATCCAC ACTTGCCTGG AACAGCTCTT CAGCCAGATT 
GATTCAATAA TCAACCTCTT GAAAGGACAA GCTGTTATAA GAGCCTTTGA GCAGACCAAG 
TATCTCACAC CGGGTCGAGG ATTGCAAGAA TTCCAACAGG AAATGGAGGC AAAGCTGAGT 
TGCCCCAGGA GGTTGCGGCT CCATCTCAAG CAGGACCCCT GGAATCTTCC CAGCAGCATC 
CAGGCGCTTG CACAGAGCAT CAGAAAACAT GCTGAAGAAG TGAAGTGCCG CATACTACTG 
GCTCTCCTTG AATACTCAGA CAGTGAAACC CAACTCCGGA GAGACATGGT TTTCTGTCAA 
AGTCTTGTGG CCACTGTCTG TGCCTTCTCT GAGCAGCTCA TGGCTGCCTT AAACCAGATG 
TTTGACAACA GCAAGGAAAA TGAAATGGAG ACTTGTGAAG CCAGCAGGAG GTGGCTGGAC 
CAGATTGCAA ATGCTGGTGT GCTTTTTCAC TTCCAGTCAC TTCTGTCACC AAATTTGAAA 
GATGAACAAG CCATGCTTGA GGATACACTG GTTGCCCTGT TTGATTTGGA AAAAGTTTCC 
TTCTTCTTCA AACCATCAGA AGAGGATCCA CTGGTTGCAA ATGTCCCTCT TACCTACCAA 
GTGGAAGGAA GCAGGCAGGC TCTGAAAGTT TACTTCTACA TGGATAGTTA CCATTTTGAG 
CAGCTGCCCC AACGGTTGAA GAATGGAGGA GGGTTTAAAA TTCATCCTGT TCTCTTTTCA 
CAAGCATTGG AGAGTATGGA AGGATATTGC TATAGAGACA ACATCTCTGT GGAAGAGTTT 
CAAGCACAAA TAAACACAGC CTCCCTGGAA AAGGTCAAAC AGTACAATCA GAAGCTCAGG 
GCATTCTACT TGGACAAGTC AAATTCCCCA CCGAATACCA CATCTAAAGC TGCCTACATA 
GATAAGCTCA TGAAGCCTCT CAATGCTTTA GATGAACTTT ACCGGCTGAT CACCTCATTT 
ATCAGATCCA AACGCATCGC TGCCTGTGTG AACACACCTT GCAGCGCCTC TGGAGTCGGA 
CTGCTGTCAG TTTCTTCAGA GCTGTGTGAC AGGCTCGGTG CCTGTCACAT CATCATGTGC 
AGCAGTGGTG TGCACCGGTG CACCCTGAGT GTGACACTAG AGCAAACCAT CACTTTAGCA 
AGAAGCCATG GGCTCCCTCC TCGGTACATT ATGCAGGCCA TGGATGTGAT GAGAAAGCAG 
GGTGCAAGAG TTCAGAACAC AGCTAAAAAC TTGGGCGTTA GAGACCGGAC TCCTCAGTCA 
GCTCCAAGGC TGTACAAGCT CTGCGAGCCA CCACCTCCAG TAGGAGAAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495504.1
CDS	521..5374
Translation	MSDESAREVDKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAAAKVDKNVTEETVKMLFSNIEEILIVHKEFLKVVEECLYPEPSAQQEVGACFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPRRHSDYTAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQAHIEGWEGSNITDTCTEMLMCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGYRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKSPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRPMKQDSIQWVYDSLESAQEDIQKSHSKPPGDGAGDAFECKVEDVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERIEHVCHRISSYGRFSRVLKNRAWPTFKQAKPKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSVEPGKLSPMVYIQHTITTMAAPSGLSLGHKDGHGLQYLLKEEDLETQDIYHKLLGKLQTALKEVEMSVCQIDDLLSSITYSPKLERKTTECVTPMDSDNEKGERNSKRVCFNVAGDEQEDSGHDTVSNRDSYSGIPTWASMFLKQHKALFCSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPISVRISHDKQDKIHTCLEQLFSQIDSIINLLKGQAVIRAFEQTKYLTPGRGLQEFQQEMEAKLSCPRRLRLHLKQDPWNLPSSIQALAQSIRKHAEEVKCRILLALLEYSDSETQLRRDMVFCQSLVATVCAFSEQLMAALNQMFDNSKENEMETCEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDTLVALFDLEKVSFFFKPSEEDPLVANVPLTYQVEGSRQALKVYFYMDSYHFEQLPQRLKNGGGFKIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRAFYLDKSNSPPNTTSKAAYIDKLMKPLNALDELYRLITSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQTITLARSHGLPPRYIMQAMDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGEE

Target ORF information:

RefSeq Version	XM_006495441.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495441.4

ORF Insert Sequence:

ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC 
AGCGAGCTGC AGAAGACCGA GCGCGACTAC GTGGGCACGC TGGAGTTCCT GGTGTCGGCC 
TTCTTGCATC GAATGAACCA ATGTGCAGCA GCAAAGGTTG ATAAAAATGT GACGGAGGAA 
ACAGTGAAGA TGTTATTCTC CAATATCGAG GAGATCCTCA TCGTTCATAA GGAGTTCTTG 
AAAGTTGTAG AAGAATGCTT ATATCCGGAA CCCAGTGCTC AGCAGGAAGT GGGAGCCTGC 
TTCCTTCACT TTAAGGACAA GTTTCGTATC TATGATGAAT ATTGCAGCAA CCATGAAAAG 
GCACAAAAAT TGCTTCTTGA ACTGAACAAA ATAAGAACAA TCCGGACATT TCTTCTGAAC 
TGCATGCTGC TTGGAGGTCG GAAGAATACA GACGTTCCCC TGGAAGGATA TTTAGTGACA 
CCAATTCAGA GGATATGCAA GTACCCTCTT CTTTTGAAGG AATTACTGAA GCGGACTCCA 
CGGAGACATA GTGACTACAC AGCAGTGATG GAAGCACTCC AAGCCATGAA AGCCGTGTGT 
TCCAACATTA ATGAGGCCAA GAGACAGATG GAGAAACTGG AAGTTTTAGA AGAGTGGCAG 
GCACACATTG AAGGCTGGGA GGGGTCCAAC ATTACTGACA CCTGTACTGA GATGCTGATG 
TGTGGAGTCC TAATGAAAAT TTCTTCCGGA AATATTCAAG AACGAGTGTT TTTTCTTTTT 
GATAATCTTT TAGTATACTG CAAAAGAAAA CACAGACGGC TGAAGAATAG TAAGGCATCC 
ACAGATGGGT ATCGGTATGT CTTTCGAGGG CGGATCAATA CTGAGGTGAT GGAAGTGGAA 
AATGTGGATG ACGGCACAGC TGATTTTCAC AGCAGTGGGC ATATTGTTGT GAATGGGTGG 
AAGATACACA ACACAGCAAA AAATAAATGG TTTGTATGCA TGGCTAAAAG CCCTGAAGAA 
AAGCATGAGT GGTTTGAAGC TATTTTGAAA GAAAGAGAAC GTCGGAAAGG GTTAAAACTA 
GGAATGGAAC AAGACACCTG GGTAATGATC TCTGAGCAGG GTGAGAAATT GTATAAAATG 
ATGTGCAAAC AGGGAAATCT GATCAAAGAC AGAAAAAGAA AACTGACCAC ATTTCCTAAG 
TGCTTCCTGG GAAGTGAATT TGTCTCATGG CTATTGGAAA TTGGAGAGAT TCACAGGCCC 
GAAGAAGGTG TTCACTTAGG ACAAGCGCTG TTAGAGAATG GGATCATCCA CCATGTTACC 
GATAAGCACC AGTTCAAACC GGAGCAAATG CTATACCGAT TCCGTTATGA CGATGGTACA 
TTTTACCCCA GGAGTGAGAT GCAGGACGTG ATTTCTAAGG GTGTAAGGCT CTACTGTCGT 
CTTCATAGTC TGTTTACCCC AGTGGTCAGA GATAAAGATT ACCATTTAAG AACTTACAAA 
TCTGTTGTCA TGGCCAACAA ATTGATAGAC TGGTTAATTG CACAGGGTGA TTGCCGTACC 
AGGGAAGAGG CAATGATATT TGCTGTTGGG CTCTGTGACA ATGGATTTAT GCATCACGTC 
CTAGAAAAAA GTGAATTCAA AGATGAGCCT CTACTTTTCC GCTTTTTTGC TGATGAGGAA 
ATGGAAGGAT CAAATATGAA GCATAGGCTT ATGAAACATG ACTTGAAGGT TGTGGAGAAT 
GTCATAGCTA AGTCACTGTT GATTAAATCC AACGAAGGCA GCTATGGCTT TGGCCTAGAA 
GACAAAAACA AAGTTCCAAT AATAAAATTA GTGGAAAAGG GGTCGAATGC CGAGATGGCT 
GGCATGGAAG TTGGGAAGAA GATATTTGCC ATTAATGGTG ACCTTGTTTT TCTGAGACCT 
TTTCCTGAAG TCGATTGCTT CCTGAAATCG TGCTTAAACA GCAGAAAGCC ACTGAGAGTC 
CTCGTGAGCA CAAAGCCAAG AGAGACCGTT AAGATTCCAG ATTCTGCAGA CGGGCTTGGT 
TTCCAGATCA GAGGCTTTGG ACCTTCAGTT GTGCATGCGG TGGGAAGAGG TACTGTGGCT 
GCAGCAGCTG GCCTTCATCC AGGACAGTGT ATTATCAAAG TGAATGGAAT CAATGTCAGC 
AAAGAGACAC ATGCCAGTGT CATCGCACAT GTCACAGCCT GCCGGAAATA CAAACGGCCA 
ATGAAGCAAG ATTCCATACA GTGGGTCTAC GACAGTCTTG AAAGTGCTCA GGAAGACATT 
CAGAAGTCCC ACTCAAAGCC CCCTGGAGAC GGGGCTGGAG ATGCTTTTGA GTGCAAAGTA 
GAAGATGTCA TTGACAAGTT CAACACCATG GCTATTATTG ATGGCAAGAA GGAGCATGTG 
AGTCTGACGG TGGACAACGT CCACCTCGAG TATGGGGTTG TATATGAGTA TGATAGCACG 
GCGGGCACAA AGTGCAATGT GGTGGAGAAG ATGGTGGAGC CCAAAGGGTT CTTCAGCCTA 
ACTGCCAAGA TTCTGGAAGC CCTAGCAAAA AGTGACGAAC ATTTTGTCCA AAACTGCACC 
AGCCTTAATT CTCTGAATGA AGTGATCGCC ACTGATCTTC AGAGTAAATT CACCAGCATG 
TGCAGTGAGA GAATCGAACA TGTGTGTCAC AGAATATCCA GCTATGGGAG GTTCTCTCGG 
GTGCTGAAGA ACAGAGCCTG GCCCACCTTT AAGCAGGCCA AACCTAAGAT CTCCCCACTG 
CACAGCAGTG ATTTCTGCCC AACCAACTGC CACGTCAATG TGATGGAAGT TTCTTATCCG 
AAAACATCAA CTTCCCTGGG GAGTGCCTTC GGTGTGCAGC TAGATAGCAG AAAACATAAT 
TCTCACGATA AAGAAAATAA ATCTGTCGAG CCAGGGAAAC TGAGCCCCAT GGTGTATATT 
CAGCACACAA TCACAACCAT GGCAGCGCCT TCGGGCCTGT CACTGGGACA CAAGGATGGG 
CATGGCCTCC AGTATTTGCT GAAAGAAGAA GACTTAGAAA CTCAAGATAT CTATCACAAA 
CTTCTGGGCA AGCTGCAGAC TGCACTGAAG GAGGTAGAGA TGAGCGTTTG TCAAATTGAT 
GACCTTCTGT CTTCAATAAC ATATTCTCCT AAATTGGAAC GTAAGACAAC AGAGTGTGTG 
ACACCAATGG ACAGTGACAA CGAGAAGGGA GAGAGAAATA GCAAACGTGT CTGTTTTAAT 
GTAGCAGGGG ATGAGCAAGA GGATTCAGGC CATGATACAG TCAGCAACAG AGACTCTTAC 
AGTGGAATAC CAACCTGGGC AAGCATGTTC TTAAAGCAAC ATAAGGCTCT TTTTTGCAGT 
GACTGCAACA GCAACAGGAA TTCCATTGCT TCCTTCACGA GTATCTGCAG CAGCCAGTGC 
AGTTCCTACT TCCACAGTGA TGAGATGGAC TCAGGTGATG AGCTTCCTAT CAGTGTCCGG 
ATATCTCATG ATAAACAAGA CAAGATCCAC ACTTGCCTGG AACAGCTCTT CAGCCAGATT 
GATTCAATAA TCAACCTCTT GAAAGGACAA GCTGTTATAA GAGCCTTTGA GCAGACCAAG 
TATCTCACAC CGGGTCGAGG ATTGCAAGAA TTCCAACAGG AAATGGAGGC AAAGCTGAGT 
TGCCCCAGGA GGTTGCGGCT CCATCTCAAG CAGGACCCCT GGAATCTTCC CAGCAGCATC 
CAGGCGCTTG CACAGAGCAT CAGAAAACAT GCTGAAGAAG TGAAGTGCCG CATACTACTG 
GCTCTCCTTG AATACTCAGA CAGTGAAACC CAACTCCGGA GAGACATGGT TTTCTGTCAA 
AGTCTTGTGG CCACTGTCTG TGCCTTCTCT GAGCAGCTCA TGGCTGCCTT AAACCAGATG 
TTTGACAACA GCAAGGAAAA TGAAATGGAG ACTTGTGAAG CCAGCAGGAG GTGGCTGGAC 
CAGATTGCAA ATGCTGGTGT GCTTTTTCAC TTCCAGTCAC TTCTGTCACC AAATTTGAAA 
GATGAACAAG CCATGCTTGA GGATACACTG GTTGCCCTGT TTGATTTGGA AAAAGTTTCC 
TTCTTCTTCA AACCATCAGA AGAGGATCCA CTGGTTGCAA ATGTCCCTCT TACCTACCAA 
GTGGAAGGAA GCAGGCAGGC TCTGAAAGTT TACTTCTACA TGGATAGTTA CCATTTTGAG 
CAGCTGCCCC AACGGTTGAA GAATGGAGGA GGGTTTAAAA TTCATCCTGT TCTCTTTTCA 
CAAGCATTGG AGAGTATGGA AGGATATTGC TATAGAGACA ACATCTCTGT GGAAGAGTTT 
CAAGCACAAA TAAACACAGC CTCCCTGGAA AAGGTCAAAC AGTACAATCA GAAGCTCAGG 
GCATTCTACT TGGACAAGTC AAATTCCCCA CCGAATACCA CATCTAAAGC TGCCTACATA 
GATAAGCTCA TGAAGCCTCT CAATGCTTTA GATGAACTTT ACCGGCTGAT CACCTCATTT 
ATCAGATCCA AACGCATCGC TGCCTGTGTG AACACACCTT GCAGCGCCTC TGGAGTCGGA 
CTGCTGTCAG TTTCTTCAGA GCTGTGTGAC AGGCTCGGTG CCTGTCACAT CATCATGTGC 
AGCAGTGGTG TGCACCGGTG CACCCTGAGT GTGACACTAG AGCAAACCAT CACTTTAGCA 
AGAAGCCATG GGCTCCCTCC TCGGTACATT ATGCAGGCCA TGGATGTGAT GAGAAAGCAG 
GGTGCAAGAG TTCAGAACAC AGCTAAAAAC TTGGGCGTTA GAGACCGGAC TCCTCAGTCA 
GCTCCAAGGC TGTACAAGCT CTGCGAGCCA CCACCTCCAG TAGGAGAAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prex2 ( NM_029525.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083801.1 Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant 1, mRNA.

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CloneID	OMu14243
Clone ID Related Accession (Same CDS sequence)	NM_029525.1
Accession Version	NM_029525.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4797bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK138884.1, AC102631.9, AC102481.10, AC164600.5 and AI553603.1. On Apr 19, 2008 this sequence version replaced XM_001475275.1. Transcript Variant: This variant (1) represents the longer variant and it encodes the longer protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AM109952.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849387 [ECO:0000348] ##Evidence-Data-END##

ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC 
AGCGAGCTGC AGAAGACCGA GCGCGACTAC GTGGGCACGC TGGAGTTCCT GGTGTCGGCC 
TTCTTGCATC GAATGAACCA ATGTGCAGCA GCAAAGGTTG ATAAAAATGT GACGGAGGAA 
ACAGTGAAGA TGTTATTCTC CAATATCGAG GAGATCCTCA TCGTTCATAA GGAGTTCTTG 
AAAGTTGTAG AAGAATGCTT ATATCCGGAA CCCAGTGCTC AGCAGGAAGT GGGAGCCTGC 
TTCCTTCACT TTAAGGACAA GTTTCGTATC TATGATGAAT ATTGCAGCAA CCATGAAAAG 
GCACAAAAAT TGCTTCTTGA ACTGAACAAA ATAAGAACAA TCCGGACATT TCTTCTGAAC 
TGCATGCTGC TTGGAGGTCG GAAGAATACA GACGTTCCCC TGGAAGGATA TTTAGTGACA 
CCAATTCAGA GGATATGCAA GTACCCTCTT CTTTTGAAGG AATTACTGAA GCGGACTCCA 
CGGAGACATA GTGACTACAC AGCAGTGATG GAAGCACTCC AAGCCATGAA AGCCGTGTGT 
TCCAACATTA ATGAGGCCAA GAGACAGATG GAGAAACTGG AAGTTTTAGA AGAGTGGCAG 
GCACACATTG AAGGCTGGGA GGGGTCCAAC ATTACTGACA CCTGTACTGA GATGCTGATG 
TGTGGAGTCC TAATGAAAAT TTCTTCCGGA AATATTCAAG AACGAGTGTT TTTTCTTTTT 
GATAATCTTT TAGTATACTG CAAAAGAAAA CACAGACGGC TGAAGAATAG TAAGGCATCC 
ACAGATGGGT ATCGGTATGT CTTTCGAGGG CGGATCAATA CTGAGGTGAT GGAAGTGGAA 
AATGTGGATG ACGGCACAGC TGATTTTCAC AGCAGTGGGC ATATTGTTGT GAATGGGTGG 
AAGATACACA ACACAGCAAA AAATAAATGG TTTGTATGCA TGGCTAAAAG CCCTGAAGAA 
AAGCATGAGT GGTTTGAAGC TATTTTGAAA GAAAGAGAAC GTCGGAAAGG GTTAAAACTA 
GGAATGGAAC AAGACACCTG GGTAATGATC TCTGAGCAGG GTGAGAAATT GTATAAAATG 
ATGTGCAAAC AGGGAAATCT GATCAAAGAC AGAAAAAGAA AACTGACCAC ATTTCCTAAG 
TGCTTCCTGG GAAGTGAATT TGTCTCATGG CTATTGGAAA TTGGAGAGAT TCACAGGCCC 
GAAGAAGGTG TTCACTTAGG ACAAGCGCTG TTAGAGAATG GGATCATCCA CCATGTTACC 
GATAAGCACC AGTTCAAACC GGAGCAAATG CTATACCGAT TCCGTTATGA CGATGGTACA 
TTTTACCCCA GGAGTGAGAT GCAGGACGTG ATTTCTAAGG GTGTAAGGCT CTACTGTCGT 
CTTCATAGTC TGTTTACCCC AGTGGTCAGA GATAAAGATT ACCATTTAAG AACTTACAAA 
TCTGTTGTCA TGGCCAACAA ATTGATAGAC TGGTTAATTG CACAGGGTGA TTGCCGTACC 
AGGGAAGAGG CAATGATATT TGCTGTTGGG CTCTGTGACA ATGGATTTAT GCATCACGTC 
CTAGAAAAAA GTGAATTCAA AGATGAGCCT CTACTTTTCC GCTTTTTTGC TGATGAGGAA 
ATGGAAGGAT CAAATATGAA GCATAGGCTT ATGAAACATG ACTTGAAGGT TGTGGAGAAT 
GTCATAGCTA AGTCACTGTT GATTAAATCC AACGAAGGCA GCTATGGCTT TGGCCTAGAA 
GACAAAAACA AAGTTCCAAT AATAAAATTA GTGGAAAAGG GGTCGAATGC CGAGATGGCT 
GGCATGGAAG TTGGGAAGAA GATATTTGCC ATTAATGGTG ACCTTGTTTT TCTGAGACCT 
TTTCCTGAAG TCGATTGCTT CCTGAAATCG TGCTTAAACA GCAGAAAGCC ACTGAGAGTC 
CTCGTGAGCA CAAAGCCAAG AGAGACCGTT AAGATTCCAG ATTCTGCAGA CGGGCTTGGT 
TTCCAGATCA GAGGCTTTGG ACCTTCAGTT GTGCATGCGG TGGGAAGAGG TACTGTGGCT 
GCAGCAGCTG GCCTTCATCC AGGACAGTGT ATTATCAAAG TGAATGGAAT CAATGTCAGC 
AAAGAGACAC ATGCCAGTGT CATCGCACAT GTCACAGCCT GCCGGAAATA CAAACGGCCA 
ATGAAGCAAG ATTCCATACA GTGGGTCTAC GACAGTCTTG AAAGTGCTCA GGAAGACATT 
CAGAAGTCCC ACTCAAAGCC CCCTGGAGAC GGGGCTGGAG ATGCTTTTGA GTGCAAAGTA 
GAAGATGTCA TTGACAAGTT CAACACCATG GCTATTATTG ATGGCAAGAA GGAGCATGTG 
AGTCTGACGG TGGACAACGT CCACCTCGAG TATGGGGTTG TATATGAGTA TGATAGCACG 
GCGGGCACAA AGTGCAATGT GGTGGAGAAG ATGGTGGAGC CCAAAGGGTT CTTCAGCCTA 
ACTGCCAAGA TTCTGGAAGC CCTAGCAAAA AGTGACGAAC ATTTTGTCCA AAACTGCACC 
AGCCTTAATT CTCTGAATGA AGTGATCGCC ACTGATCTTC AGAGTAAATT CACCAGCATG 
TGCAGTGAGA GAATCGAACA TGTGTGTCAC AGAATATCCA GCTATGGGAG GTTCTCTCGG 
GTGCTGAAGA ACAGAGCCTG GCCCACCTTT AAGCAGGCCA AACCTAAGAT CTCCCCACTG 
CACAGCAGTG ATTTCTGCCC AACCAACTGC CACGTCAATG TGATGGAAGT TTCTTATCCG 
AAAACATCAA CTTCCCTGGG GAGTGCCTTC GGTGTGCAGC TAGATAGCAG AAAACATAAT 
TCTCACGATA AAGAAAATAA ATCTGTCGAG CCAGGGAAAC TGAGCCCCAT GGTGTATATT 
CAGCACACAA TCACAACCAT GGCAGCGCCT TCGGGCCTGT CACTGGGACA CAAGGATGGG 
CATGGCCTCC AGTATTTGCT GAAAGAAGAA GACTTAGAAA CTCAAGATAT CTATCACAAA 
CTTCTGGGCA AGCTGCAGAC TGCACTGAAG GAGGTAGAGA TGAGCGTTTG TCAAATTGAT 
GACCTTCTGT CTTCAATAAC ATATTCTCCT AAATTGGAAC GTAAGACAAC AGAGTGTGTG 
ACACCAATGG ACAGTGACAA CGAGAAGGGA GAGAGAAATA GCAAACGTGT CTGTTTTAAT 
GTAGCAGGGG ATGAGCAAGA GGATTCAGGC CATGATACAG TCAGCAACAG AGACTCTTAC 
AGTGACTGCA ACAGCAACAG GAATTCCATT GCTTCCTTCA CGAGTATCTG CAGCAGCCAG 
TGCAGTTCCT ACTTCCACAG TGATGAGATG GACTCAGGTG ATGAGCTTCC TATCAGTGTC 
CGGATATCTC ATGATAAACA AGACAAGATC CACACTTGCC TGGAACAGCT CTTCAGCCAG 
ATTGATTCAA TAATCAACCT CTTGAAAGGA CAAGCTGTTA TAAGAGCCTT TGAGCAGACC 
AAGTATCTCA CACCGGGTCG AGGATTGCAA GAATTCCAAC AGGAAATGGA GGCAAAGCTG 
AGTTGCCCCA GGAGGTTGCG GCTCCATCTC AAGCAGGACC CCTGGAATCT TCCCAGCAGC 
ATCCAGGCGC TTGCACAGAG CATCAGAAAA CATGCTGAAG AAGTGAAGTG CCGCATACTA 
CTGGCTCTCC TTGAATACTC AGACAGTGAA ACCCAACTCC GGAGAGACAT GGTTTTCTGT 
CAAAGTCTTG TGGCCACTGT CTGTGCCTTC TCTGAGCAGC TCATGGCTGC CTTAAACCAG 
ATGTTTGACA ACAGCAAGGA AAATGAAATG GAGACTTGTG AAGCCAGCAG GAGGTGGCTG 
GACCAGATTG CAAATGCTGG TGTGCTTTTT CACTTCCAGT CACTTCTGTC ACCAAATTTG 
AAAGATGAAC AAGCCATGCT TGAGGATACA CTGGTTGCCC TGTTTGATTT GGAAAAAGTT 
TCCTTCTTCT TCAAACCATC AGAAGAGGAT CCACTGGTTG CAAATGTCCC TCTTACCTAC 
CAAGTGGAAG GAAGCAGGCA GGCTCTGAAA GTTTACTTCT ACATGGATAG TTACCATTTT 
GAGCAGCTGC CCCAACGGTT GAAGAATGGA GGAGGGTTTA AAATTCATCC TGTTCTCTTT 
TCACAAGCAT TGGAGAGTAT GGAAGGATAT TGCTATAGAG ACAACATCTC TGTGGAAGAG 
TTTCAAGCAC AAATAAACAC AGCCTCCCTG GAAAAGGTCA AACAGTACAA TCAGAAGCTC 
AGGGCATTCT ACTTGGACAA GTCAAATTCC CCACCGAATA CCACATCTAA AGCTGCCTAC 
ATAGATAAGC TCATGAAGCC TCTCAATGCT TTAGATGAAC TTTACCGGCT GATCACCTCA 
TTTATCAGAT CCAAACGCAT CGCTGCCTGT GTGAACACAC CTTGCAGCGC CTCTGGAGTC 
GGACTGCTGT CAGTTTCTTC AGAGCTGTGT GACAGGCTCG GTGCCTGTCA CATCATCATG 
TGCAGCAGTG GTGTGCACCG GTGCACCCTG AGTGTGACAC TAGAGCAAAC CATCACTTTA 
GCAAGAAGCC ATGGGCTCCC TCCTCGGTAC ATTATGCAGG CCATGGATGT GATGAGAAAG 
CAGGGTGCAA GAGTTCAGAA CACAGCTAAA AACTTGGGCG TTAGAGACCG GACTCCTCAG 
TCAGCTCCAA GGCTGTACAA GCTCTGCGAG CCACCACCTC CAGTAGGAGA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083801.1
CDS	329..5125
Translation	MSDESAREVDKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAAAKVDKNVTEETVKMLFSNIEEILIVHKEFLKVVEECLYPEPSAQQEVGACFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPRRHSDYTAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQAHIEGWEGSNITDTCTEMLMCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGYRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKSPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRPMKQDSIQWVYDSLESAQEDIQKSHSKPPGDGAGDAFECKVEDVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERIEHVCHRISSYGRFSRVLKNRAWPTFKQAKPKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSVEPGKLSPMVYIQHTITTMAAPSGLSLGHKDGHGLQYLLKEEDLETQDIYHKLLGKLQTALKEVEMSVCQIDDLLSSITYSPKLERKTTECVTPMDSDNEKGERNSKRVCFNVAGDEQEDSGHDTVSNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPISVRISHDKQDKIHTCLEQLFSQIDSIINLLKGQAVIRAFEQTKYLTPGRGLQEFQQEMEAKLSCPRRLRLHLKQDPWNLPSSIQALAQSIRKHAEEVKCRILLALLEYSDSETQLRRDMVFCQSLVATVCAFSEQLMAALNQMFDNSKENEMETCEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDTLVALFDLEKVSFFFKPSEEDPLVANVPLTYQVEGSRQALKVYFYMDSYHFEQLPQRLKNGGGFKIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRAFYLDKSNSPPNTTSKAAYIDKLMKPLNALDELYRLITSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQTITLARSHGLPPRYIMQAMDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGEE

Target ORF information:

RefSeq Version	NM_029525.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029525.1

ORF Insert Sequence:

ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC 
AGCGAGCTGC AGAAGACCGA GCGCGACTAC GTGGGCACGC TGGAGTTCCT GGTGTCGGCC 
TTCTTGCATC GAATGAACCA ATGTGCAGCA GCAAAGGTTG ATAAAAATGT GACGGAGGAA 
ACAGTGAAGA TGTTATTCTC CAATATCGAG GAGATCCTCA TCGTTCATAA GGAGTTCTTG 
AAAGTTGTAG AAGAATGCTT ATATCCGGAA CCCAGTGCTC AGCAGGAAGT GGGAGCCTGC 
TTCCTTCACT TTAAGGACAA GTTTCGTATC TATGATGAAT ATTGCAGCAA CCATGAAAAG 
GCACAAAAAT TGCTTCTTGA ACTGAACAAA ATAAGAACAA TCCGGACATT TCTTCTGAAC 
TGCATGCTGC TTGGAGGTCG GAAGAATACA GACGTTCCCC TGGAAGGATA TTTAGTGACA 
CCAATTCAGA GGATATGCAA GTACCCTCTT CTTTTGAAGG AATTACTGAA GCGGACTCCA 
CGGAGACATA GTGACTACAC AGCAGTGATG GAAGCACTCC AAGCCATGAA AGCCGTGTGT 
TCCAACATTA ATGAGGCCAA GAGACAGATG GAGAAACTGG AAGTTTTAGA AGAGTGGCAG 
GCACACATTG AAGGCTGGGA GGGGTCCAAC ATTACTGACA CCTGTACTGA GATGCTGATG 
TGTGGAGTCC TAATGAAAAT TTCTTCCGGA AATATTCAAG AACGAGTGTT TTTTCTTTTT 
GATAATCTTT TAGTATACTG CAAAAGAAAA CACAGACGGC TGAAGAATAG TAAGGCATCC 
ACAGATGGGT ATCGGTATGT CTTTCGAGGG CGGATCAATA CTGAGGTGAT GGAAGTGGAA 
AATGTGGATG ACGGCACAGC TGATTTTCAC AGCAGTGGGC ATATTGTTGT GAATGGGTGG 
AAGATACACA ACACAGCAAA AAATAAATGG TTTGTATGCA TGGCTAAAAG CCCTGAAGAA 
AAGCATGAGT GGTTTGAAGC TATTTTGAAA GAAAGAGAAC GTCGGAAAGG GTTAAAACTA 
GGAATGGAAC AAGACACCTG GGTAATGATC TCTGAGCAGG GTGAGAAATT GTATAAAATG 
ATGTGCAAAC AGGGAAATCT GATCAAAGAC AGAAAAAGAA AACTGACCAC ATTTCCTAAG 
TGCTTCCTGG GAAGTGAATT TGTCTCATGG CTATTGGAAA TTGGAGAGAT TCACAGGCCC 
GAAGAAGGTG TTCACTTAGG ACAAGCGCTG TTAGAGAATG GGATCATCCA CCATGTTACC 
GATAAGCACC AGTTCAAACC GGAGCAAATG CTATACCGAT TCCGTTATGA CGATGGTACA 
TTTTACCCCA GGAGTGAGAT GCAGGACGTG ATTTCTAAGG GTGTAAGGCT CTACTGTCGT 
CTTCATAGTC TGTTTACCCC AGTGGTCAGA GATAAAGATT ACCATTTAAG AACTTACAAA 
TCTGTTGTCA TGGCCAACAA ATTGATAGAC TGGTTAATTG CACAGGGTGA TTGCCGTACC 
AGGGAAGAGG CAATGATATT TGCTGTTGGG CTCTGTGACA ATGGATTTAT GCATCACGTC 
CTAGAAAAAA GTGAATTCAA AGATGAGCCT CTACTTTTCC GCTTTTTTGC TGATGAGGAA 
ATGGAAGGAT CAAATATGAA GCATAGGCTT ATGAAACATG ACTTGAAGGT TGTGGAGAAT 
GTCATAGCTA AGTCACTGTT GATTAAATCC AACGAAGGCA GCTATGGCTT TGGCCTAGAA 
GACAAAAACA AAGTTCCAAT AATAAAATTA GTGGAAAAGG GGTCGAATGC CGAGATGGCT 
GGCATGGAAG TTGGGAAGAA GATATTTGCC ATTAATGGTG ACCTTGTTTT TCTGAGACCT 
TTTCCTGAAG TCGATTGCTT CCTGAAATCG TGCTTAAACA GCAGAAAGCC ACTGAGAGTC 
CTCGTGAGCA CAAAGCCAAG AGAGACCGTT AAGATTCCAG ATTCTGCAGA CGGGCTTGGT 
TTCCAGATCA GAGGCTTTGG ACCTTCAGTT GTGCATGCGG TGGGAAGAGG TACTGTGGCT 
GCAGCAGCTG GCCTTCATCC AGGACAGTGT ATTATCAAAG TGAATGGAAT CAATGTCAGC 
AAAGAGACAC ATGCCAGTGT CATCGCACAT GTCACAGCCT GCCGGAAATA CAAACGGCCA 
ATGAAGCAAG ATTCCATACA GTGGGTCTAC GACAGTCTTG AAAGTGCTCA GGAAGACATT 
CAGAAGTCCC ACTCAAAGCC CCCTGGAGAC GGGGCTGGAG ATGCTTTTGA GTGCAAAGTA 
GAAGATGTCA TTGACAAGTT CAACACCATG GCTATTATTG ATGGCAAGAA GGAGCATGTG 
AGTCTGACGG TGGACAACGT CCACCTCGAG TATGGGGTTG TATATGAGTA TGATAGCACG 
GCGGGCACAA AGTGCAATGT GGTGGAGAAG ATGGTGGAGC CCAAAGGGTT CTTCAGCCTA 
ACTGCCAAGA TTCTGGAAGC CCTAGCAAAA AGTGACGAAC ATTTTGTCCA AAACTGCACC 
AGCCTTAATT CTCTGAATGA AGTGATCGCC ACTGATCTTC AGAGTAAATT CACCAGCATG 
TGCAGTGAGA GAATCGAACA TGTGTGTCAC AGAATATCCA GCTATGGGAG GTTCTCTCGG 
GTGCTGAAGA ACAGAGCCTG GCCCACCTTT AAGCAGGCCA AACCTAAGAT CTCCCCACTG 
CACAGCAGTG ATTTCTGCCC AACCAACTGC CACGTCAATG TGATGGAAGT TTCTTATCCG 
AAAACATCAA CTTCCCTGGG GAGTGCCTTC GGTGTGCAGC TAGATAGCAG AAAACATAAT 
TCTCACGATA AAGAAAATAA ATCTGTCGAG CCAGGGAAAC TGAGCCCCAT GGTGTATATT 
CAGCACACAA TCACAACCAT GGCAGCGCCT TCGGGCCTGT CACTGGGACA CAAGGATGGG 
CATGGCCTCC AGTATTTGCT GAAAGAAGAA GACTTAGAAA CTCAAGATAT CTATCACAAA 
CTTCTGGGCA AGCTGCAGAC TGCACTGAAG GAGGTAGAGA TGAGCGTTTG TCAAATTGAT 
GACCTTCTGT CTTCAATAAC ATATTCTCCT AAATTGGAAC GTAAGACAAC AGAGTGTGTG 
ACACCAATGG ACAGTGACAA CGAGAAGGGA GAGAGAAATA GCAAACGTGT CTGTTTTAAT 
GTAGCAGGGG ATGAGCAAGA GGATTCAGGC CATGATACAG TCAGCAACAG AGACTCTTAC 
AGTGACTGCA ACAGCAACAG GAATTCCATT GCTTCCTTCA CGAGTATCTG CAGCAGCCAG 
TGCAGTTCCT ACTTCCACAG TGATGAGATG GACTCAGGTG ATGAGCTTCC TATCAGTGTC 
CGGATATCTC ATGATAAACA AGACAAGATC CACACTTGCC TGGAACAGCT CTTCAGCCAG 
ATTGATTCAA TAATCAACCT CTTGAAAGGA CAAGCTGTTA TAAGAGCCTT TGAGCAGACC 
AAGTATCTCA CACCGGGTCG AGGATTGCAA GAATTCCAAC AGGAAATGGA GGCAAAGCTG 
AGTTGCCCCA GGAGGTTGCG GCTCCATCTC AAGCAGGACC CCTGGAATCT TCCCAGCAGC 
ATCCAGGCGC TTGCACAGAG CATCAGAAAA CATGCTGAAG AAGTGAAGTG CCGCATACTA 
CTGGCTCTCC TTGAATACTC AGACAGTGAA ACCCAACTCC GGAGAGACAT GGTTTTCTGT 
CAAAGTCTTG TGGCCACTGT CTGTGCCTTC TCTGAGCAGC TCATGGCTGC CTTAAACCAG 
ATGTTTGACA ACAGCAAGGA AAATGAAATG GAGACTTGTG AAGCCAGCAG GAGGTGGCTG 
GACCAGATTG CAAATGCTGG TGTGCTTTTT CACTTCCAGT CACTTCTGTC ACCAAATTTG 
AAAGATGAAC AAGCCATGCT TGAGGATACA CTGGTTGCCC TGTTTGATTT GGAAAAAGTT 
TCCTTCTTCT TCAAACCATC AGAAGAGGAT CCACTGGTTG CAAATGTCCC TCTTACCTAC 
CAAGTGGAAG GAAGCAGGCA GGCTCTGAAA GTTTACTTCT ACATGGATAG TTACCATTTT 
GAGCAGCTGC CCCAACGGTT GAAGAATGGA GGAGGGTTTA AAATTCATCC TGTTCTCTTT 
TCACAAGCAT TGGAGAGTAT GGAAGGATAT TGCTATAGAG ACAACATCTC TGTGGAAGAG 
TTTCAAGCAC AAATAAACAC AGCCTCCCTG GAAAAGGTCA AACAGTACAA TCAGAAGCTC 
AGGGCATTCT ACTTGGACAA GTCAAATTCC CCACCGAATA CCACATCTAA AGCTGCCTAC 
ATAGATAAGC TCATGAAGCC TCTCAATGCT TTAGATGAAC TTTACCGGCT GATCACCTCA 
TTTATCAGAT CCAAACGCAT CGCTGCCTGT GTGAACACAC CTTGCAGCGC CTCTGGAGTC 
GGACTGCTGT CAGTTTCTTC AGAGCTGTGT GACAGGCTCG GTGCCTGTCA CATCATCATG 
TGCAGCAGTG GTGTGCACCG GTGCACCCTG AGTGTGACAC TAGAGCAAAC CATCACTTTA 
GCAAGAAGCC ATGGGCTCCC TCCTCGGTAC ATTATGCAGG CCATGGATGT GATGAGAAAG 
CAGGGTGCAA GAGTTCAGAA CACAGCTAAA AACTTGGGCG TTAGAGACCG GACTCCTCAG 
TCAGCTCCAA GGCTGTACAA GCTCTGCGAG CCACCACCTC CAGTAGGAGA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prex2 ( XM_006495441.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495504.1 Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant X1, mRNA.

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CloneID	OMu27099
Clone ID Related Accession (Same CDS sequence)	XM_006495441.4 , XM_006495441.3
Accession Version	XM_006495441.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4854bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006495441.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC 
AGCGAGCTGC AGAAGACCGA GCGCGACTAC GTGGGCACGC TGGAGTTCCT GGTGTCGGCC 
TTCTTGCATC GAATGAACCA ATGTGCAGCA GCAAAGGTTG ATAAAAATGT GACGGAGGAA 
ACAGTGAAGA TGTTATTCTC CAATATCGAG GAGATCCTCA TCGTTCATAA GGAGTTCTTG 
AAAGTTGTAG AAGAATGCTT ATATCCGGAA CCCAGTGCTC AGCAGGAAGT GGGAGCCTGC 
TTCCTTCACT TTAAGGACAA GTTTCGTATC TATGATGAAT ATTGCAGCAA CCATGAAAAG 
GCACAAAAAT TGCTTCTTGA ACTGAACAAA ATAAGAACAA TCCGGACATT TCTTCTGAAC 
TGCATGCTGC TTGGAGGTCG GAAGAATACA GACGTTCCCC TGGAAGGATA TTTAGTGACA 
CCAATTCAGA GGATATGCAA GTACCCTCTT CTTTTGAAGG AATTACTGAA GCGGACTCCA 
CGGAGACATA GTGACTACAC AGCAGTGATG GAAGCACTCC AAGCCATGAA AGCCGTGTGT 
TCCAACATTA ATGAGGCCAA GAGACAGATG GAGAAACTGG AAGTTTTAGA AGAGTGGCAG 
GCACACATTG AAGGCTGGGA GGGGTCCAAC ATTACTGACA CCTGTACTGA GATGCTGATG 
TGTGGAGTCC TAATGAAAAT TTCTTCCGGA AATATTCAAG AACGAGTGTT TTTTCTTTTT 
GATAATCTTT TAGTATACTG CAAAAGAAAA CACAGACGGC TGAAGAATAG TAAGGCATCC 
ACAGATGGGT ATCGGTATGT CTTTCGAGGG CGGATCAATA CTGAGGTGAT GGAAGTGGAA 
AATGTGGATG ACGGCACAGC TGATTTTCAC AGCAGTGGGC ATATTGTTGT GAATGGGTGG 
AAGATACACA ACACAGCAAA AAATAAATGG TTTGTATGCA TGGCTAAAAG CCCTGAAGAA 
AAGCATGAGT GGTTTGAAGC TATTTTGAAA GAAAGAGAAC GTCGGAAAGG GTTAAAACTA 
GGAATGGAAC AAGACACCTG GGTAATGATC TCTGAGCAGG GTGAGAAATT GTATAAAATG 
ATGTGCAAAC AGGGAAATCT GATCAAAGAC AGAAAAAGAA AACTGACCAC ATTTCCTAAG 
TGCTTCCTGG GAAGTGAATT TGTCTCATGG CTATTGGAAA TTGGAGAGAT TCACAGGCCC 
GAAGAAGGTG TTCACTTAGG ACAAGCGCTG TTAGAGAATG GGATCATCCA CCATGTTACC 
GATAAGCACC AGTTCAAACC GGAGCAAATG CTATACCGAT TCCGTTATGA CGATGGTACA 
TTTTACCCCA GGAGTGAGAT GCAGGACGTG ATTTCTAAGG GTGTAAGGCT CTACTGTCGT 
CTTCATAGTC TGTTTACCCC AGTGGTCAGA GATAAAGATT ACCATTTAAG AACTTACAAA 
TCTGTTGTCA TGGCCAACAA ATTGATAGAC TGGTTAATTG CACAGGGTGA TTGCCGTACC 
AGGGAAGAGG CAATGATATT TGCTGTTGGG CTCTGTGACA ATGGATTTAT GCATCACGTC 
CTAGAAAAAA GTGAATTCAA AGATGAGCCT CTACTTTTCC GCTTTTTTGC TGATGAGGAA 
ATGGAAGGAT CAAATATGAA GCATAGGCTT ATGAAACATG ACTTGAAGGT TGTGGAGAAT 
GTCATAGCTA AGTCACTGTT GATTAAATCC AACGAAGGCA GCTATGGCTT TGGCCTAGAA 
GACAAAAACA AAGTTCCAAT AATAAAATTA GTGGAAAAGG GGTCGAATGC CGAGATGGCT 
GGCATGGAAG TTGGGAAGAA GATATTTGCC ATTAATGGTG ACCTTGTTTT TCTGAGACCT 
TTTCCTGAAG TCGATTGCTT CCTGAAATCG TGCTTAAACA GCAGAAAGCC ACTGAGAGTC 
CTCGTGAGCA CAAAGCCAAG AGAGACCGTT AAGATTCCAG ATTCTGCAGA CGGGCTTGGT 
TTCCAGATCA GAGGCTTTGG ACCTTCAGTT GTGCATGCGG TGGGAAGAGG TACTGTGGCT 
GCAGCAGCTG GCCTTCATCC AGGACAGTGT ATTATCAAAG TGAATGGAAT CAATGTCAGC 
AAAGAGACAC ATGCCAGTGT CATCGCACAT GTCACAGCCT GCCGGAAATA CAAACGGCCA 
ATGAAGCAAG ATTCCATACA GTGGGTCTAC GACAGTCTTG AAAGTGCTCA GGAAGACATT 
CAGAAGTCCC ACTCAAAGCC CCCTGGAGAC GGGGCTGGAG ATGCTTTTGA GTGCAAAGTA 
GAAGATGTCA TTGACAAGTT CAACACCATG GCTATTATTG ATGGCAAGAA GGAGCATGTG 
AGTCTGACGG TGGACAACGT CCACCTCGAG TATGGGGTTG TATATGAGTA TGATAGCACG 
GCGGGCACAA AGTGCAATGT GGTGGAGAAG ATGGTGGAGC CCAAAGGGTT CTTCAGCCTA 
ACTGCCAAGA TTCTGGAAGC CCTAGCAAAA AGTGACGAAC ATTTTGTCCA AAACTGCACC 
AGCCTTAATT CTCTGAATGA AGTGATCGCC ACTGATCTTC AGAGTAAATT CACCAGCATG 
TGCAGTGAGA GAATCGAACA TGTGTGTCAC AGAATATCCA GCTATGGGAG GTTCTCTCGG 
GTGCTGAAGA ACAGAGCCTG GCCCACCTTT AAGCAGGCCA AACCTAAGAT CTCCCCACTG 
CACAGCAGTG ATTTCTGCCC AACCAACTGC CACGTCAATG TGATGGAAGT TTCTTATCCG 
AAAACATCAA CTTCCCTGGG GAGTGCCTTC GGTGTGCAGC TAGATAGCAG AAAACATAAT 
TCTCACGATA AAGAAAATAA ATCTGTCGAG CCAGGGAAAC TGAGCCCCAT GGTGTATATT 
CAGCACACAA TCACAACCAT GGCAGCGCCT TCGGGCCTGT CACTGGGACA CAAGGATGGG 
CATGGCCTCC AGTATTTGCT GAAAGAAGAA GACTTAGAAA CTCAAGATAT CTATCACAAA 
CTTCTGGGCA AGCTGCAGAC TGCACTGAAG GAGGTAGAGA TGAGCGTTTG TCAAATTGAT 
GACCTTCTGT CTTCAATAAC ATATTCTCCT AAATTGGAAC GTAAGACAAC AGAGTGTGTG 
ACACCAATGG ACAGTGACAA CGAGAAGGGA GAGAGAAATA GCAAACGTGT CTGTTTTAAT 
GTAGCAGGGG ATGAGCAAGA GGATTCAGGC CATGATACAG TCAGCAACAG AGACTCTTAC 
AGTGGAATAC CAACCTGGGC AAGCATGTTC TTAAAGCAAC ATAAGGCTCT TTTTTGCAGT 
GACTGCAACA GCAACAGGAA TTCCATTGCT TCCTTCACGA GTATCTGCAG CAGCCAGTGC 
AGTTCCTACT TCCACAGTGA TGAGATGGAC TCAGGTGATG AGCTTCCTAT CAGTGTCCGG 
ATATCTCATG ATAAACAAGA CAAGATCCAC ACTTGCCTGG AACAGCTCTT CAGCCAGATT 
GATTCAATAA TCAACCTCTT GAAAGGACAA GCTGTTATAA GAGCCTTTGA GCAGACCAAG 
TATCTCACAC CGGGTCGAGG ATTGCAAGAA TTCCAACAGG AAATGGAGGC AAAGCTGAGT 
TGCCCCAGGA GGTTGCGGCT CCATCTCAAG CAGGACCCCT GGAATCTTCC CAGCAGCATC 
CAGGCGCTTG CACAGAGCAT CAGAAAACAT GCTGAAGAAG TGAAGTGCCG CATACTACTG 
GCTCTCCTTG AATACTCAGA CAGTGAAACC CAACTCCGGA GAGACATGGT TTTCTGTCAA 
AGTCTTGTGG CCACTGTCTG TGCCTTCTCT GAGCAGCTCA TGGCTGCCTT AAACCAGATG 
TTTGACAACA GCAAGGAAAA TGAAATGGAG ACTTGTGAAG CCAGCAGGAG GTGGCTGGAC 
CAGATTGCAA ATGCTGGTGT GCTTTTTCAC TTCCAGTCAC TTCTGTCACC AAATTTGAAA 
GATGAACAAG CCATGCTTGA GGATACACTG GTTGCCCTGT TTGATTTGGA AAAAGTTTCC 
TTCTTCTTCA AACCATCAGA AGAGGATCCA CTGGTTGCAA ATGTCCCTCT TACCTACCAA 
GTGGAAGGAA GCAGGCAGGC TCTGAAAGTT TACTTCTACA TGGATAGTTA CCATTTTGAG 
CAGCTGCCCC AACGGTTGAA GAATGGAGGA GGGTTTAAAA TTCATCCTGT TCTCTTTTCA 
CAAGCATTGG AGAGTATGGA AGGATATTGC TATAGAGACA ACATCTCTGT GGAAGAGTTT 
CAAGCACAAA TAAACACAGC CTCCCTGGAA AAGGTCAAAC AGTACAATCA GAAGCTCAGG 
GCATTCTACT TGGACAAGTC AAATTCCCCA CCGAATACCA CATCTAAAGC TGCCTACATA 
GATAAGCTCA TGAAGCCTCT CAATGCTTTA GATGAACTTT ACCGGCTGAT CACCTCATTT 
ATCAGATCCA AACGCATCGC TGCCTGTGTG AACACACCTT GCAGCGCCTC TGGAGTCGGA 
CTGCTGTCAG TTTCTTCAGA GCTGTGTGAC AGGCTCGGTG CCTGTCACAT CATCATGTGC 
AGCAGTGGTG TGCACCGGTG CACCCTGAGT GTGACACTAG AGCAAACCAT CACTTTAGCA 
AGAAGCCATG GGCTCCCTCC TCGGTACATT ATGCAGGCCA TGGATGTGAT GAGAAAGCAG 
GGTGCAAGAG TTCAGAACAC AGCTAAAAAC TTGGGCGTTA GAGACCGGAC TCCTCAGTCA 
GCTCCAAGGC TGTACAAGCT CTGCGAGCCA CCACCTCCAG TAGGAGAAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495504.1
CDS	522..5375
Translation	MSDESAREVDKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAAAKVDKNVTEETVKMLFSNIEEILIVHKEFLKVVEECLYPEPSAQQEVGACFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPRRHSDYTAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQAHIEGWEGSNITDTCTEMLMCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGYRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKSPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRPMKQDSIQWVYDSLESAQEDIQKSHSKPPGDGAGDAFECKVEDVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERIEHVCHRISSYGRFSRVLKNRAWPTFKQAKPKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSVEPGKLSPMVYIQHTITTMAAPSGLSLGHKDGHGLQYLLKEEDLETQDIYHKLLGKLQTALKEVEMSVCQIDDLLSSITYSPKLERKTTECVTPMDSDNEKGERNSKRVCFNVAGDEQEDSGHDTVSNRDSYSGIPTWASMFLKQHKALFCSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPISVRISHDKQDKIHTCLEQLFSQIDSIINLLKGQAVIRAFEQTKYLTPGRGLQEFQQEMEAKLSCPRRLRLHLKQDPWNLPSSIQALAQSIRKHAEEVKCRILLALLEYSDSETQLRRDMVFCQSLVATVCAFSEQLMAALNQMFDNSKENEMETCEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDTLVALFDLEKVSFFFKPSEEDPLVANVPLTYQVEGSRQALKVYFYMDSYHFEQLPQRLKNGGGFKIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRAFYLDKSNSPPNTTSKAAYIDKLMKPLNALDELYRLITSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQTITLARSHGLPPRYIMQAMDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGEE

Target ORF information:

RefSeq Version	XM_006495441.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495441.3

ORF Insert Sequence:

ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC 
AGCGAGCTGC AGAAGACCGA GCGCGACTAC GTGGGCACGC TGGAGTTCCT GGTGTCGGCC 
TTCTTGCATC GAATGAACCA ATGTGCAGCA GCAAAGGTTG ATAAAAATGT GACGGAGGAA 
ACAGTGAAGA TGTTATTCTC CAATATCGAG GAGATCCTCA TCGTTCATAA GGAGTTCTTG 
AAAGTTGTAG AAGAATGCTT ATATCCGGAA CCCAGTGCTC AGCAGGAAGT GGGAGCCTGC 
TTCCTTCACT TTAAGGACAA GTTTCGTATC TATGATGAAT ATTGCAGCAA CCATGAAAAG 
GCACAAAAAT TGCTTCTTGA ACTGAACAAA ATAAGAACAA TCCGGACATT TCTTCTGAAC 
TGCATGCTGC TTGGAGGTCG GAAGAATACA GACGTTCCCC TGGAAGGATA TTTAGTGACA 
CCAATTCAGA GGATATGCAA GTACCCTCTT CTTTTGAAGG AATTACTGAA GCGGACTCCA 
CGGAGACATA GTGACTACAC AGCAGTGATG GAAGCACTCC AAGCCATGAA AGCCGTGTGT 
TCCAACATTA ATGAGGCCAA GAGACAGATG GAGAAACTGG AAGTTTTAGA AGAGTGGCAG 
GCACACATTG AAGGCTGGGA GGGGTCCAAC ATTACTGACA CCTGTACTGA GATGCTGATG 
TGTGGAGTCC TAATGAAAAT TTCTTCCGGA AATATTCAAG AACGAGTGTT TTTTCTTTTT 
GATAATCTTT TAGTATACTG CAAAAGAAAA CACAGACGGC TGAAGAATAG TAAGGCATCC 
ACAGATGGGT ATCGGTATGT CTTTCGAGGG CGGATCAATA CTGAGGTGAT GGAAGTGGAA 
AATGTGGATG ACGGCACAGC TGATTTTCAC AGCAGTGGGC ATATTGTTGT GAATGGGTGG 
AAGATACACA ACACAGCAAA AAATAAATGG TTTGTATGCA TGGCTAAAAG CCCTGAAGAA 
AAGCATGAGT GGTTTGAAGC TATTTTGAAA GAAAGAGAAC GTCGGAAAGG GTTAAAACTA 
GGAATGGAAC AAGACACCTG GGTAATGATC TCTGAGCAGG GTGAGAAATT GTATAAAATG 
ATGTGCAAAC AGGGAAATCT GATCAAAGAC AGAAAAAGAA AACTGACCAC ATTTCCTAAG 
TGCTTCCTGG GAAGTGAATT TGTCTCATGG CTATTGGAAA TTGGAGAGAT TCACAGGCCC 
GAAGAAGGTG TTCACTTAGG ACAAGCGCTG TTAGAGAATG GGATCATCCA CCATGTTACC 
GATAAGCACC AGTTCAAACC GGAGCAAATG CTATACCGAT TCCGTTATGA CGATGGTACA 
TTTTACCCCA GGAGTGAGAT GCAGGACGTG ATTTCTAAGG GTGTAAGGCT CTACTGTCGT 
CTTCATAGTC TGTTTACCCC AGTGGTCAGA GATAAAGATT ACCATTTAAG AACTTACAAA 
TCTGTTGTCA TGGCCAACAA ATTGATAGAC TGGTTAATTG CACAGGGTGA TTGCCGTACC 
AGGGAAGAGG CAATGATATT TGCTGTTGGG CTCTGTGACA ATGGATTTAT GCATCACGTC 
CTAGAAAAAA GTGAATTCAA AGATGAGCCT CTACTTTTCC GCTTTTTTGC TGATGAGGAA 
ATGGAAGGAT CAAATATGAA GCATAGGCTT ATGAAACATG ACTTGAAGGT TGTGGAGAAT 
GTCATAGCTA AGTCACTGTT GATTAAATCC AACGAAGGCA GCTATGGCTT TGGCCTAGAA 
GACAAAAACA AAGTTCCAAT AATAAAATTA GTGGAAAAGG GGTCGAATGC CGAGATGGCT 
GGCATGGAAG TTGGGAAGAA GATATTTGCC ATTAATGGTG ACCTTGTTTT TCTGAGACCT 
TTTCCTGAAG TCGATTGCTT CCTGAAATCG TGCTTAAACA GCAGAAAGCC ACTGAGAGTC 
CTCGTGAGCA CAAAGCCAAG AGAGACCGTT AAGATTCCAG ATTCTGCAGA CGGGCTTGGT 
TTCCAGATCA GAGGCTTTGG ACCTTCAGTT GTGCATGCGG TGGGAAGAGG TACTGTGGCT 
GCAGCAGCTG GCCTTCATCC AGGACAGTGT ATTATCAAAG TGAATGGAAT CAATGTCAGC 
AAAGAGACAC ATGCCAGTGT CATCGCACAT GTCACAGCCT GCCGGAAATA CAAACGGCCA 
ATGAAGCAAG ATTCCATACA GTGGGTCTAC GACAGTCTTG AAAGTGCTCA GGAAGACATT 
CAGAAGTCCC ACTCAAAGCC CCCTGGAGAC GGGGCTGGAG ATGCTTTTGA GTGCAAAGTA 
GAAGATGTCA TTGACAAGTT CAACACCATG GCTATTATTG ATGGCAAGAA GGAGCATGTG 
AGTCTGACGG TGGACAACGT CCACCTCGAG TATGGGGTTG TATATGAGTA TGATAGCACG 
GCGGGCACAA AGTGCAATGT GGTGGAGAAG ATGGTGGAGC CCAAAGGGTT CTTCAGCCTA 
ACTGCCAAGA TTCTGGAAGC CCTAGCAAAA AGTGACGAAC ATTTTGTCCA AAACTGCACC 
AGCCTTAATT CTCTGAATGA AGTGATCGCC ACTGATCTTC AGAGTAAATT CACCAGCATG 
TGCAGTGAGA GAATCGAACA TGTGTGTCAC AGAATATCCA GCTATGGGAG GTTCTCTCGG 
GTGCTGAAGA ACAGAGCCTG GCCCACCTTT AAGCAGGCCA AACCTAAGAT CTCCCCACTG 
CACAGCAGTG ATTTCTGCCC AACCAACTGC CACGTCAATG TGATGGAAGT TTCTTATCCG 
AAAACATCAA CTTCCCTGGG GAGTGCCTTC GGTGTGCAGC TAGATAGCAG AAAACATAAT 
TCTCACGATA AAGAAAATAA ATCTGTCGAG CCAGGGAAAC TGAGCCCCAT GGTGTATATT 
CAGCACACAA TCACAACCAT GGCAGCGCCT TCGGGCCTGT CACTGGGACA CAAGGATGGG 
CATGGCCTCC AGTATTTGCT GAAAGAAGAA GACTTAGAAA CTCAAGATAT CTATCACAAA 
CTTCTGGGCA AGCTGCAGAC TGCACTGAAG GAGGTAGAGA TGAGCGTTTG TCAAATTGAT 
GACCTTCTGT CTTCAATAAC ATATTCTCCT AAATTGGAAC GTAAGACAAC AGAGTGTGTG 
ACACCAATGG ACAGTGACAA CGAGAAGGGA GAGAGAAATA GCAAACGTGT CTGTTTTAAT 
GTAGCAGGGG ATGAGCAAGA GGATTCAGGC CATGATACAG TCAGCAACAG AGACTCTTAC 
AGTGGAATAC CAACCTGGGC AAGCATGTTC TTAAAGCAAC ATAAGGCTCT TTTTTGCAGT 
GACTGCAACA GCAACAGGAA TTCCATTGCT TCCTTCACGA GTATCTGCAG CAGCCAGTGC 
AGTTCCTACT TCCACAGTGA TGAGATGGAC TCAGGTGATG AGCTTCCTAT CAGTGTCCGG 
ATATCTCATG ATAAACAAGA CAAGATCCAC ACTTGCCTGG AACAGCTCTT CAGCCAGATT 
GATTCAATAA TCAACCTCTT GAAAGGACAA GCTGTTATAA GAGCCTTTGA GCAGACCAAG 
TATCTCACAC CGGGTCGAGG ATTGCAAGAA TTCCAACAGG AAATGGAGGC AAAGCTGAGT 
TGCCCCAGGA GGTTGCGGCT CCATCTCAAG CAGGACCCCT GGAATCTTCC CAGCAGCATC 
CAGGCGCTTG CACAGAGCAT CAGAAAACAT GCTGAAGAAG TGAAGTGCCG CATACTACTG 
GCTCTCCTTG AATACTCAGA CAGTGAAACC CAACTCCGGA GAGACATGGT TTTCTGTCAA 
AGTCTTGTGG CCACTGTCTG TGCCTTCTCT GAGCAGCTCA TGGCTGCCTT AAACCAGATG 
TTTGACAACA GCAAGGAAAA TGAAATGGAG ACTTGTGAAG CCAGCAGGAG GTGGCTGGAC 
CAGATTGCAA ATGCTGGTGT GCTTTTTCAC TTCCAGTCAC TTCTGTCACC AAATTTGAAA 
GATGAACAAG CCATGCTTGA GGATACACTG GTTGCCCTGT TTGATTTGGA AAAAGTTTCC 
TTCTTCTTCA AACCATCAGA AGAGGATCCA CTGGTTGCAA ATGTCCCTCT TACCTACCAA 
GTGGAAGGAA GCAGGCAGGC TCTGAAAGTT TACTTCTACA TGGATAGTTA CCATTTTGAG 
CAGCTGCCCC AACGGTTGAA GAATGGAGGA GGGTTTAAAA TTCATCCTGT TCTCTTTTCA 
CAAGCATTGG AGAGTATGGA AGGATATTGC TATAGAGACA ACATCTCTGT GGAAGAGTTT 
CAAGCACAAA TAAACACAGC CTCCCTGGAA AAGGTCAAAC AGTACAATCA GAAGCTCAGG 
GCATTCTACT TGGACAAGTC AAATTCCCCA CCGAATACCA CATCTAAAGC TGCCTACATA 
GATAAGCTCA TGAAGCCTCT CAATGCTTTA GATGAACTTT ACCGGCTGAT CACCTCATTT 
ATCAGATCCA AACGCATCGC TGCCTGTGTG AACACACCTT GCAGCGCCTC TGGAGTCGGA 
CTGCTGTCAG TTTCTTCAGA GCTGTGTGAC AGGCTCGGTG CCTGTCACAT CATCATGTGC 
AGCAGTGGTG TGCACCGGTG CACCCTGAGT GTGACACTAG AGCAAACCAT CACTTTAGCA 
AGAAGCCATG GGCTCCCTCC TCGGTACATT ATGCAGGCCA TGGATGTGAT GAGAAAGCAG 
GGTGCAAGAG TTCAGAACAC AGCTAAAAAC TTGGGCGTTA GAGACCGGAC TCCTCAGTCA 
GCTCCAAGGC TGTACAAGCT CTGCGAGCCA CCACCTCCAG TAGGAGAAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma.
Small GTPases7(3)178-85(2016 Jul)
Lissanu Deribe Y

Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Proceedings of the National Academy of Sciences of the United States of America113(9)E1296-305(2016 Mar)
Lissanu Deribe Y,Shi Y,Rai K,Nezi L,Amin SB,Wu CC,Akdemir KC,Mahdavi M,Peng Q,Chang QE,Hornigold K,Arold ST,Welch HC,Garraway LA,Chin L

PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.
Science signaling8(370)ra32(2015 Mar)
Mense SM,Barrows D,Hodakoski C,Steinbach N,Schoenfeld D,Su W,Hopkins BD,Su T,Fine B,Hibshoosh H,Parsons R

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.
Blood125(7)1146-58(2015 Feb)
Pan D,Amison RT,Riffo-Vasquez Y,Spina D,Cleary SJ,Wakelam MJ,Page CP,Pitchford SC,Welch HC

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.
Journal of cell science127(Pt 11)2589-600(2014 Jun)
Damoulakis G,Gambardella L,Rossman KL,Lawson CD,Anderson KE,Fukui Y,Welch HC,Der CJ,Stephens LR,Hawkins PT

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Prex2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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