Slco1a5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slco1a5
Entrez Gene ID	108096
Full Name	solute carrier organic anion transporter family, member 1a5
Synonyms	Oatp-3,Oatp3,Slc21a7
General protein information	Preferred Names solute carrier organic anion transporter family, member 1a5 Names solute carrier organic anion transporter family member 1A5 organic anion-transporting polypeptide 3 sodium-independent organic anion transporter 3 solute carrier family 21 (organic anion transporter), member 7 solute carrier family 21 member 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 G2

mRNA and Protein(s)

mRNA	Protein	Name
NM_130861.3	NP_570931.1	solute carrier organic anion transporter family member 1A5
NM_001267707.1	NP_001254636.1	solute carrier organic anion transporter family member 1A5

Pathways from BioSystems

Homologies

	SLCO1A2	XP_001097987.1
Rattus norvegicus (Norway rat)	Slco1a5	NP_110465.1
Homo sapiens (human)	SLCO1A2	NP_602307.1
Bos taurus (cattle)	SLCO1A2	NP_777079.1
Gallus gallus (chicken)	SLCO1A2	XP_416421.3
Mus musculus (house mouse)	Slco1a5	NP_001254636.1
Pan troglodytes (chimpanzee)	SLCO1A2	XP_001151598.1
Canis lupus familiaris (dog)	SLCO1A2	XP_005637129.1

Gene Ontology
Bibliography

Related articles in PubMed

The targeted inactivation of TR? gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.
Selmi-Ruby S, Bouazza L, Obregon MJ, Conscience A, Flamant F, Samarut J, Borson-Chazot F, Rousset B
Endocrinology155(2)635-46(2014 Feb)

Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.
Di Cosmo C, Liao XH, Dumitrescu AM, Philp NJ, Weiss RE, Refetoff S
The Journal of clinical investigation120(9)3377-88(2010 Sep)

Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.
van de Steeg E, Wagenaar E, van der Kruijssen CM, Burggraaff JE, de Waart DR, Elferink RP, Kenworthy KE, Schinkel AH
The Journal of clinical investigation120(8)2942-52(2010 Aug)

PDZK1 regulates organic anion transporting polypeptide Oatp1a in mouse small intestine.
Sugiura T, Otake T, Shimizu T, Wakayama T, Silver DL, Utsumi R, Nishimura T, Iseki S, Nakamichi N, Kubo Y, Tsuji A, Kato Y
Drug metabolism and pharmacokinetics25(6)588-98(2010)

Molecular physiology of renal organic anion transporters.
Sekine T, Miyazaki H, Endou H
American journal of physiology. Renal physiology290(2)F251-61(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Immunoreactivity to anti-Oatp1a antibody was colocalized with PDZK1 in the small intestine of wild-type mice, whereas apical localization of Oatp1a protein was reduced in pdzk1(-/-) mice. PDZK1 appears to act as an adaptor for Oatp1a[Oatp1a]
Title: PDZK1 regulates organic anion transporting polypeptide Oatp1a in mouse small intestine.

The following Slco1a5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slco1a5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06669	NM_001267707.1 Latest version!	Mus musculus solute carrier organic anion transporter family, member 1a5 (Slco1a5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu06669	NM_130861.3 Latest version!	Mus musculus solute carrier organic anion transporter family, member 1a5 (Slco1a5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slco1a5 ( NM_130861.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_570931.1 Mus musculus solute carrier organic anion transporter family, member 1a5 (Slco1a5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu06669
Clone ID Related Accession (Same CDS sequence)	NM_130861.3 , NM_001267707.1
Accession Version	NM_130861.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Mus musculus(house mouse)
Product	solute carrier organic anion transporter family member 1A5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK029706.1. On Jun 13, 2012 this sequence version replaced NM_130861.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK029706.1, AF240694.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGAAA CAGAGAAAAG GATTGCAACC CATGGGGTCA GATGCTTTTC TAAGATCAAG 
ATGTTTCTGT TGGCATTAAC ATGTGCATAT GTATCCAAAT CACTCTCAGG AATTTATATG 
AATTCCATGC TTACACAAAT AGAGAGACAA TTCGATATCC CCACATCTAT AGTTGGACTT 
ATCAATGGGA GCTTTGAGAT TGGAAATCTT TTGTTGATTA TACTCGTGAG TTACTTTGGA 
ACAAAATTGC ACAGACCTAT CATGATTGGT ATTGGATGTG TGATTATGGG CCTAGGGTGT 
TTCTTAATGT CCTTACCTCA TTTCCTCATG GGCCGATACG AATATGAAAC AACGATTTCA 
CCTACAAGCA ACTTGTCCTC AAACAGCTTC TTGTGTATGG AAAACAGAAC ACAGACCTTA 
AAGCCAACGC AAGACCCTGC AGAGTGTGTG AAAGAAATGA AATCATTAAT GTGGATATAT 
GTACTGGTAG GAAACATCAT ACGTGGAATT GGTGAAACTC CCATCATGCC CTTGGGTATT 
TCCTACATAG AAGATTTTGC CAAATCTGAA AACTCTCCTT TATATATTGG GATTTTAGAA 
TCAGGAAAGA TGATTGGCCC AATTGTTGGA CTTTTGTTGG GATCCTTCTG TGCAAGAATT 
TATGTAGACA CAGGGTCTGT GAATACAGAT GACCTGACCA TAACTCCCAC TGATACACGC 
TGGGTCGGTG CTTGGTGGAT TGGCTTTTTG GTCTGTGCAG GAGTGAATAT CCTGACCAGC 
ATCCCCTTTT TCTTCTTTCC AAAAACACTC CCAAAGGAAG GATTACAGGA TAATGTGGAT 
AGAACTGAAA ATGACAAAGA GGAGAAGCAC AGAGAAAAAG CCAAGGAGGA AAACCGAGGA 
ATCACTAAAG ATTTCCTGCC ATTCATGAAG AGCCTCTCCT GCAATCCTAT TTACATGCTT 
CTCATCCTGA CAAGTGTGCT CCAGATAAAC GCATTTATCA ATATGTTTAC CTTCTTGCCC 
AAATACCTGG AGCAGCAGTA TGGAAAATCC ACTTCAGAGG TCGTCCTCCT CATAGGTGTT 
TGTAACTTAC CTCCAATCTG CATTGGATAT TTACTTATTG GCTTTATTAT GAAGAAGTTC 
AGGATTACTG TCAAGAAGGC TGCATACATG GCATTCTGCC TATCCCTGTT TGAGTACCTT 
CTGTCTTACT TTCACTTTAT GATAAGCTGT GATAATTTCC AAGTTGCTGG CTTAACTACC 
TCTTATGAAG GAGTTCAGCA CCCTCTATAT GTGGAGAACA AGGTCCTTGC TGACTGCAAC 
ACAAGGTGTA GCTGCTTAAC AAACACATGG GATCCAGTGT GTGGAGACAA TGGCCTATCA 
TACATGTCAG CCTGCCTCGC GGGCTGTGAG AAGTCTGTTG GAATGGGAAC CCACATGGTG 
TTTCAAAATT GCAGCTGCAT TCAGTCATCA GGAAACTCAT CTGCAGTCCT GGGGCTGTGT 
AAAAAAGGCC CTGAGTGTGC TAACAAGCTG CAGTACTTTT TAATCATGTC GGTAATTGGC 
AGTTTCATCT ATTCGATCAC AGCCATACCT GGGTACATGG TTCTTCTGAG GTGTATCAAG 
TCTGAAGAGA AGTCCCTTGG AATTGGATTA CACGCATTTT GCACAAGAAT ATTCGCTGGC 
ATCCCTGCAC CCATTTACTT TGGAGCTTTG ATAGACAGAA CCTGCTTACA TTGGGGAACT 
CTGAAATGTG GTGAGCCAGG AGCCTGTAGG ATGTACAATA TAAATAACTT CAGGCGCATT 
TATCTAGTGT TGCCTGCAGC ACTAAGAGGA TCAAGCTATC TCCCTGCATT CTTCATTCTG 
ATACTTATGA GGAAATTCCA GCTCCCTGGG GAAATGTACT CTTCTGAAAC TGAACTTGCA 
GACATGAAGC TCACAGTGAA GAAAAGCGAG TGCACAGATG TGCACAGAAT TCCTAAGGTC 
GAGAATGATG GAGAACTGAA AACTAAGCTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570931.1
CDS	125..2137
Translation	MGETEKRIATHGVRCFSKIKMFLLALTCAYVSKSLSGIYMNSMLTQIERQFDIPTSIVGLINGSFEIGNLLLIILVSYFGTKLHRPIMIGIGCVIMGLGCFLMSLPHFLMGRYEYETTISPTSNLSSNSFLCMENRTQTLKPTQDPAECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGILESGKMIGPIVGLLLGSFCARIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTLPKEGLQDNVDRTENDKEEKHREKAKEENRGITKDFLPFMKSLSCNPIYMLLILTSVLQINAFINMFTFLPKYLEQQYGKSTSEVVLLIGVCNLPPICIGYLLIGFIMKKFRITVKKAAYMAFCLSLFEYLLSYFHFMISCDNFQVAGLTTSYEGVQHPLYVENKVLADCNTRCSCLTNTWDPVCGDNGLSYMSACLAGCEKSVGMGTHMVFQNCSCIQSSGNSSAVLGLCKKGPECANKLQYFLIMSVIGSFIYSITAIPGYMVLLRCIKSEEKSLGIGLHAFCTRIFAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYNINNFRRIYLVLPAALRGSSYLPAFFILILMRKFQLPGEMYSSETELADMKLTVKKSECTDVHRIPKVENDGELKTKL

Target ORF information:

RefSeq Version	NM_130861.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier organic anion transporter family, member 1a5 (Slco1a5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130861.3

ORF Insert Sequence:

ATGGGAGAAA CAGAGAAAAG GATTGCAACC CATGGGGTCA GATGCTTTTC TAAGATCAAG 
ATGTTTCTGT TGGCATTAAC ATGTGCATAT GTATCCAAAT CACTCTCAGG AATTTATATG 
AATTCCATGC TTACACAAAT AGAGAGACAA TTCGATATCC CCACATCTAT AGTTGGACTT 
ATCAATGGGA GCTTTGAGAT TGGAAATCTT TTGTTGATTA TACTCGTGAG TTACTTTGGA 
ACAAAATTGC ACAGACCTAT CATGATTGGT ATTGGATGTG TGATTATGGG CCTAGGGTGT 
TTCTTAATGT CCTTACCTCA TTTCCTCATG GGCCGATACG AATATGAAAC AACGATTTCA 
CCTACAAGCA ACTTGTCCTC AAACAGCTTC TTGTGTATGG AAAACAGAAC ACAGACCTTA 
AAGCCAACGC AAGACCCTGC AGAGTGTGTG AAAGAAATGA AATCATTAAT GTGGATATAT 
GTACTGGTAG GAAACATCAT ACGTGGAATT GGTGAAACTC CCATCATGCC CTTGGGTATT 
TCCTACATAG AAGATTTTGC CAAATCTGAA AACTCTCCTT TATATATTGG GATTTTAGAA 
TCAGGAAAGA TGATTGGCCC AATTGTTGGA CTTTTGTTGG GATCCTTCTG TGCAAGAATT 
TATGTAGACA CAGGGTCTGT GAATACAGAT GACCTGACCA TAACTCCCAC TGATACACGC 
TGGGTCGGTG CTTGGTGGAT TGGCTTTTTG GTCTGTGCAG GAGTGAATAT CCTGACCAGC 
ATCCCCTTTT TCTTCTTTCC AAAAACACTC CCAAAGGAAG GATTACAGGA TAATGTGGAT 
AGAACTGAAA ATGACAAAGA GGAGAAGCAC AGAGAAAAAG CCAAGGAGGA AAACCGAGGA 
ATCACTAAAG ATTTCCTGCC ATTCATGAAG AGCCTCTCCT GCAATCCTAT TTACATGCTT 
CTCATCCTGA CAAGTGTGCT CCAGATAAAC GCATTTATCA ATATGTTTAC CTTCTTGCCC 
AAATACCTGG AGCAGCAGTA TGGAAAATCC ACTTCAGAGG TCGTCCTCCT CATAGGTGTT 
TGTAACTTAC CTCCAATCTG CATTGGATAT TTACTTATTG GCTTTATTAT GAAGAAGTTC 
AGGATTACTG TCAAGAAGGC TGCATACATG GCATTCTGCC TATCCCTGTT TGAGTACCTT 
CTGTCTTACT TTCACTTTAT GATAAGCTGT GATAATTTCC AAGTTGCTGG CTTAACTACC 
TCTTATGAAG GAGTTCAGCA CCCTCTATAT GTGGAGAACA AGGTCCTTGC TGACTGCAAC 
ACAAGGTGTA GCTGCTTAAC AAACACATGG GATCCAGTGT GTGGAGACAA TGGCCTATCA 
TACATGTCAG CCTGCCTCGC GGGCTGTGAG AAGTCTGTTG GAATGGGAAC CCACATGGTG 
TTTCAAAATT GCAGCTGCAT TCAGTCATCA GGAAACTCAT CTGCAGTCCT GGGGCTGTGT 
AAAAAAGGCC CTGAGTGTGC TAACAAGCTG CAGTACTTTT TAATCATGTC GGTAATTGGC 
AGTTTCATCT ATTCGATCAC AGCCATACCT GGGTACATGG TTCTTCTGAG GTGTATCAAG 
TCTGAAGAGA AGTCCCTTGG AATTGGATTA CACGCATTTT GCACAAGAAT ATTCGCTGGC 
ATCCCTGCAC CCATTTACTT TGGAGCTTTG ATAGACAGAA CCTGCTTACA TTGGGGAACT 
CTGAAATGTG GTGAGCCAGG AGCCTGTAGG ATGTACAATA TAAATAACTT CAGGCGCATT 
TATCTAGTGT TGCCTGCAGC ACTAAGAGGA TCAAGCTATC TCCCTGCATT CTTCATTCTG 
ATACTTATGA GGAAATTCCA GCTCCCTGGG GAAATGTACT CTTCTGAAAC TGAACTTGCA 
GACATGAAGC TCACAGTGAA GAAAAGCGAG TGCACAGATG TGCACAGAAT TCCTAAGGTC 
GAGAATGATG GAGAACTGAA AACTAAGCTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slco1a5 ( NM_001267707.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001254636.1 Mus musculus solute carrier organic anion transporter family, member 1a5 (Slco1a5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu06669
Clone ID Related Accession (Same CDS sequence)	NM_130861.3 , NM_001267707.1
Accession Version	NM_001267707.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Mus musculus(house mouse)
Product	solute carrier organic anion transporter family member 1A5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102125.13 and FQ790388.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC013594.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGAAA CAGAGAAAAG GATTGCAACC CATGGGGTCA GATGCTTTTC TAAGATCAAG 
ATGTTTCTGT TGGCATTAAC ATGTGCATAT GTATCCAAAT CACTCTCAGG AATTTATATG 
AATTCCATGC TTACACAAAT AGAGAGACAA TTCGATATCC CCACATCTAT AGTTGGACTT 
ATCAATGGGA GCTTTGAGAT TGGAAATCTT TTGTTGATTA TACTCGTGAG TTACTTTGGA 
ACAAAATTGC ACAGACCTAT CATGATTGGT ATTGGATGTG TGATTATGGG CCTAGGGTGT 
TTCTTAATGT CCTTACCTCA TTTCCTCATG GGCCGATACG AATATGAAAC AACGATTTCA 
CCTACAAGCA ACTTGTCCTC AAACAGCTTC TTGTGTATGG AAAACAGAAC ACAGACCTTA 
AAGCCAACGC AAGACCCTGC AGAGTGTGTG AAAGAAATGA AATCATTAAT GTGGATATAT 
GTACTGGTAG GAAACATCAT ACGTGGAATT GGTGAAACTC CCATCATGCC CTTGGGTATT 
TCCTACATAG AAGATTTTGC CAAATCTGAA AACTCTCCTT TATATATTGG GATTTTAGAA 
TCAGGAAAGA TGATTGGCCC AATTGTTGGA CTTTTGTTGG GATCCTTCTG TGCAAGAATT 
TATGTAGACA CAGGGTCTGT GAATACAGAT GACCTGACCA TAACTCCCAC TGATACACGC 
TGGGTCGGTG CTTGGTGGAT TGGCTTTTTG GTCTGTGCAG GAGTGAATAT CCTGACCAGC 
ATCCCCTTTT TCTTCTTTCC AAAAACACTC CCAAAGGAAG GATTACAGGA TAATGTGGAT 
AGAACTGAAA ATGACAAAGA GGAGAAGCAC AGAGAAAAAG CCAAGGAGGA AAACCGAGGA 
ATCACTAAAG ATTTCCTGCC ATTCATGAAG AGCCTCTCCT GCAATCCTAT TTACATGCTT 
CTCATCCTGA CAAGTGTGCT CCAGATAAAC GCATTTATCA ATATGTTTAC CTTCTTGCCC 
AAATACCTGG AGCAGCAGTA TGGAAAATCC ACTTCAGAGG TCGTCCTCCT CATAGGTGTT 
TGTAACTTAC CTCCAATCTG CATTGGATAT TTACTTATTG GCTTTATTAT GAAGAAGTTC 
AGGATTACTG TCAAGAAGGC TGCATACATG GCATTCTGCC TATCCCTGTT TGAGTACCTT 
CTGTCTTACT TTCACTTTAT GATAAGCTGT GATAATTTCC AAGTTGCTGG CTTAACTACC 
TCTTATGAAG GAGTTCAGCA CCCTCTATAT GTGGAGAACA AGGTCCTTGC TGACTGCAAC 
ACAAGGTGTA GCTGCTTAAC AAACACATGG GATCCAGTGT GTGGAGACAA TGGCCTATCA 
TACATGTCAG CCTGCCTCGC GGGCTGTGAG AAGTCTGTTG GAATGGGAAC CCACATGGTG 
TTTCAAAATT GCAGCTGCAT TCAGTCATCA GGAAACTCAT CTGCAGTCCT GGGGCTGTGT 
AAAAAAGGCC CTGAGTGTGC TAACAAGCTG CAGTACTTTT TAATCATGTC GGTAATTGGC 
AGTTTCATCT ATTCGATCAC AGCCATACCT GGGTACATGG TTCTTCTGAG GTGTATCAAG 
TCTGAAGAGA AGTCCCTTGG AATTGGATTA CACGCATTTT GCACAAGAAT ATTCGCTGGC 
ATCCCTGCAC CCATTTACTT TGGAGCTTTG ATAGACAGAA CCTGCTTACA TTGGGGAACT 
CTGAAATGTG GTGAGCCAGG AGCCTGTAGG ATGTACAATA TAAATAACTT CAGGCGCATT 
TATCTAGTGT TGCCTGCAGC ACTAAGAGGA TCAAGCTATC TCCCTGCATT CTTCATTCTG 
ATACTTATGA GGAAATTCCA GCTCCCTGGG GAAATGTACT CTTCTGAAAC TGAACTTGCA 
GACATGAAGC TCACAGTGAA GAAAAGCGAG TGCACAGATG TGCACAGAAT TCCTAAGGTC 
GAGAATGATG GAGAACTGAA AACTAAGCTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254636.1
CDS	177..2189
Translation	MGETEKRIATHGVRCFSKIKMFLLALTCAYVSKSLSGIYMNSMLTQIERQFDIPTSIVGLINGSFEIGNLLLIILVSYFGTKLHRPIMIGIGCVIMGLGCFLMSLPHFLMGRYEYETTISPTSNLSSNSFLCMENRTQTLKPTQDPAECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGILESGKMIGPIVGLLLGSFCARIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTLPKEGLQDNVDRTENDKEEKHREKAKEENRGITKDFLPFMKSLSCNPIYMLLILTSVLQINAFINMFTFLPKYLEQQYGKSTSEVVLLIGVCNLPPICIGYLLIGFIMKKFRITVKKAAYMAFCLSLFEYLLSYFHFMISCDNFQVAGLTTSYEGVQHPLYVENKVLADCNTRCSCLTNTWDPVCGDNGLSYMSACLAGCEKSVGMGTHMVFQNCSCIQSSGNSSAVLGLCKKGPECANKLQYFLIMSVIGSFIYSITAIPGYMVLLRCIKSEEKSLGIGLHAFCTRIFAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYNINNFRRIYLVLPAALRGSSYLPAFFILILMRKFQLPGEMYSSETELADMKLTVKKSECTDVHRIPKVENDGELKTKL

Target ORF information:

RefSeq Version	NM_001267707.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier organic anion transporter family, member 1a5 (Slco1a5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267707.1

ORF Insert Sequence:

ATGGGAGAAA CAGAGAAAAG GATTGCAACC CATGGGGTCA GATGCTTTTC TAAGATCAAG 
ATGTTTCTGT TGGCATTAAC ATGTGCATAT GTATCCAAAT CACTCTCAGG AATTTATATG 
AATTCCATGC TTACACAAAT AGAGAGACAA TTCGATATCC CCACATCTAT AGTTGGACTT 
ATCAATGGGA GCTTTGAGAT TGGAAATCTT TTGTTGATTA TACTCGTGAG TTACTTTGGA 
ACAAAATTGC ACAGACCTAT CATGATTGGT ATTGGATGTG TGATTATGGG CCTAGGGTGT 
TTCTTAATGT CCTTACCTCA TTTCCTCATG GGCCGATACG AATATGAAAC AACGATTTCA 
CCTACAAGCA ACTTGTCCTC AAACAGCTTC TTGTGTATGG AAAACAGAAC ACAGACCTTA 
AAGCCAACGC AAGACCCTGC AGAGTGTGTG AAAGAAATGA AATCATTAAT GTGGATATAT 
GTACTGGTAG GAAACATCAT ACGTGGAATT GGTGAAACTC CCATCATGCC CTTGGGTATT 
TCCTACATAG AAGATTTTGC CAAATCTGAA AACTCTCCTT TATATATTGG GATTTTAGAA 
TCAGGAAAGA TGATTGGCCC AATTGTTGGA CTTTTGTTGG GATCCTTCTG TGCAAGAATT 
TATGTAGACA CAGGGTCTGT GAATACAGAT GACCTGACCA TAACTCCCAC TGATACACGC 
TGGGTCGGTG CTTGGTGGAT TGGCTTTTTG GTCTGTGCAG GAGTGAATAT CCTGACCAGC 
ATCCCCTTTT TCTTCTTTCC AAAAACACTC CCAAAGGAAG GATTACAGGA TAATGTGGAT 
AGAACTGAAA ATGACAAAGA GGAGAAGCAC AGAGAAAAAG CCAAGGAGGA AAACCGAGGA 
ATCACTAAAG ATTTCCTGCC ATTCATGAAG AGCCTCTCCT GCAATCCTAT TTACATGCTT 
CTCATCCTGA CAAGTGTGCT CCAGATAAAC GCATTTATCA ATATGTTTAC CTTCTTGCCC 
AAATACCTGG AGCAGCAGTA TGGAAAATCC ACTTCAGAGG TCGTCCTCCT CATAGGTGTT 
TGTAACTTAC CTCCAATCTG CATTGGATAT TTACTTATTG GCTTTATTAT GAAGAAGTTC 
AGGATTACTG TCAAGAAGGC TGCATACATG GCATTCTGCC TATCCCTGTT TGAGTACCTT 
CTGTCTTACT TTCACTTTAT GATAAGCTGT GATAATTTCC AAGTTGCTGG CTTAACTACC 
TCTTATGAAG GAGTTCAGCA CCCTCTATAT GTGGAGAACA AGGTCCTTGC TGACTGCAAC 
ACAAGGTGTA GCTGCTTAAC AAACACATGG GATCCAGTGT GTGGAGACAA TGGCCTATCA 
TACATGTCAG CCTGCCTCGC GGGCTGTGAG AAGTCTGTTG GAATGGGAAC CCACATGGTG 
TTTCAAAATT GCAGCTGCAT TCAGTCATCA GGAAACTCAT CTGCAGTCCT GGGGCTGTGT 
AAAAAAGGCC CTGAGTGTGC TAACAAGCTG CAGTACTTTT TAATCATGTC GGTAATTGGC 
AGTTTCATCT ATTCGATCAC AGCCATACCT GGGTACATGG TTCTTCTGAG GTGTATCAAG 
TCTGAAGAGA AGTCCCTTGG AATTGGATTA CACGCATTTT GCACAAGAAT ATTCGCTGGC 
ATCCCTGCAC CCATTTACTT TGGAGCTTTG ATAGACAGAA CCTGCTTACA TTGGGGAACT 
CTGAAATGTG GTGAGCCAGG AGCCTGTAGG ATGTACAATA TAAATAACTT CAGGCGCATT 
TATCTAGTGT TGCCTGCAGC ACTAAGAGGA TCAAGCTATC TCCCTGCATT CTTCATTCTG 
ATACTTATGA GGAAATTCCA GCTCCCTGGG GAAATGTACT CTTCTGAAAC TGAACTTGCA 
GACATGAAGC TCACAGTGAA GAAAAGCGAG TGCACAGATG TGCACAGAAT TCCTAAGGTC 
GAGAATGATG GAGAACTGAA AACTAAGCTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The targeted inactivation of TR? gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.
Endocrinology155(2)635-46(2014 Feb)
Selmi-Ruby S,Bouazza L,Obregon MJ,Conscience A,Flamant F,Samarut J,Borson-Chazot F,Rousset B

Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.
The Journal of clinical investigation120(9)3377-88(2010 Sep)
Di Cosmo C,Liao XH,Dumitrescu AM,Philp NJ,Weiss RE,Refetoff S

Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.
The Journal of clinical investigation120(8)2942-52(2010 Aug)
van de Steeg E,Wagenaar E,van der Kruijssen CM,Burggraaff JE,de Waart DR,Elferink RP,Kenworthy KE,Schinkel AH

PDZK1 regulates organic anion transporting polypeptide Oatp1a in mouse small intestine.
Drug metabolism and pharmacokinetics25(6)588-98(2010)
Sugiura T,Otake T,Shimizu T,Wakayama T,Silver DL,Utsumi R,Nishimura T,Iseki S,Nakamichi N,Kubo Y,Tsuji A,Kato Y

Molecular physiology of renal organic anion transporters.
American journal of physiology. Renal physiology290(2)F251-61(2006 Feb)
Sekine T,Miyazaki H,Endou H

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Slco1a5 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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