Ildr1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ildr1
Entrez Gene ID	106347
Full Name	immunoglobulin-like domain containing receptor 1
Synonyms	AU041483,AU044638
General protein information	Preferred Names immunoglobulin-like domain containing receptor 1 Names immunoglobulin-like domain-containing receptor 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_134109.2	NP_598870.1	immunoglobulin-like domain-containing receptor 1 isoform 2 precursor
XM_006521674.3	XP_006521737.1	immunoglobulin-like domain-containing receptor 1 isoform X1
NM_001285788.1	NP_001272717.1	immunoglobulin-like domain-containing receptor 1 isoform 1 precursor
XM_006521674.4	XP_006521737.1	immunoglobulin-like domain-containing receptor 1 isoform X1
NM_001285791.1	NP_001272720.1	immunoglobulin-like domain-containing receptor 1 isoform 3 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ildr1	NP_001272717.1
Rattus norvegicus (Norway rat)	Ildr1	NP_001121008.2
Canis lupus familiaris (dog)	ILDR1	XP_005639611.1
Homo sapiens (human)	ILDR1	NP_001186728.1
Pan troglodytes (chimpanzee)	ILDR1	XP_526282.3
	ILDR1	XP_001111791.1
Danio rerio (zebrafish)	ildr1b	NP_001004642.1
Danio rerio (zebrafish)	ildr1a	NP_956687.1
Xenopus tropicalis (tropical clawed frog)	LOC100486057	XP_002940967.1
Bos taurus (cattle)	ILDR1	NP_001095684.1
Gallus gallus (chicken)	ILDR1	XP_004938277.1

Gene Ontology
Bibliography

Related articles in PubMed

ILDR1 is important for paracellular water transport and urine concentration mechanism.
Gong Y, Himmerkus N, Sunq A, Milatz S, Merkel C, Bleich M, Hou J
Proceedings of the National Academy of Sciences of the United States of America114(20)5271-5276(2017 May)

ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42.
Sang Q, Li W, Xu Y, Qu R, Xu Z, Feng R, Jin L, He L, Li H, Wang L
Biology open4(4)411-8(2015 Mar)

ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.
Morozko EL, Nishio A, Ingham NJ, Chandra R, Fitzgerald T, Martelletti E, Borck G, Wilson E, Riordan GP, Wangemann P, Forge A, Steel KP, Liddle RA, Friedman TB, Belyantseva IA
Human molecular genetics24(3)609-24(2015 Feb)

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y
PloS one10(3)e0121550(2015)

Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice.
Higashi T, Katsuno T, Kitajiri S, Furuse M
PloS one10(3)e0120674(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study consolidate the importance of ILDR1 as a tight junction protein necessary for cochlear hair cells survival, and the integrity of the auditory system.
Title: ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.

The angulin-2/ILDR1 deficiency causes the postnatal degenerative loss of hair cells in the cochlea.
Title: Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice.

ILDR1 regulates CCK release through a mechanism dependent on fatty acids and lipoproteins.
Title: Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion.

The findings show the heterogeneity of the molecular organization of tTJs in terms of the content of LSR, ILDR1 or ILDR2, and suggest that ILDR1-mediated recruitment of tricellulin to TCs is required for hearing.
Title: Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.

The following Ildr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ildr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10545	NM_134109.2 Latest version!	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00
OMu17300	NM_001285788.1 Latest version!	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu17231	NM_001285791.1 Latest version!	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu51789	XM_006521674.4 Latest version!	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu51789	XM_006521674.3	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ildr1 ( NM_134109.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598870.1 Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 2, mRNA.

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CloneID	OMu10545
Clone ID Related Accession (Same CDS sequence)	NM_134109.2
Accession Version	NM_134109.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	immunoglobulin-like domain-containing receptor 1 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK136284.1, AK036844.1 and AC117662.13. On Oct 23, 2013 this sequence version replaced NM_134109.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC010485.1, AK036844.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTGCG GATTGCTCGC TGCTGGCCTG CTCCTCTTCA CCTGGCTCCC AGCAGGGTGT 
CTGTCCTTGC TAGTCACAGT CCAGCACACA GAACGCTATG TTACTCTGTT TGCCTCCGTT 
ACCCTCAAGT GTGACTACAC CACCTCTGCC CAGCTCCAGG ACGTGGTTGT GACATGGCGC 
TTCAAGTCCT TCTGCAAGGA TCCCATCTTT GACTACTTCT CTGCCTCATA CCAGGCAGCT 
TTGTCCCTGG GCCAGGACCC CTCCAATGAC TGTAGTGACA ATCAGAGGGA AGTTCGCATC 
GTGGCGCAGC GGCGTGGGCA GAGTGAGCCC GTGCTGGGGG TGGATTACCG GCAACGCAAG 
ATCACCATCC AGAACCGAGC AGATCTTGTG ATTAATGAAG TGATGTGGTG GGATCATGGA 
GTATACTATT GTACCATCGA GGCTCCAGGA GACACGTCAG GAGACCCAGA TAAGGAGGTG 
AAGCTCATTG TCCTGCATTG GCTGACAGTG ATTTTCATCA TTCTTGGAGC CCTCCTACTC 
CTGCTGCTGA TTGGTGTATG CTGGTGCCAG TGTTGTCCGC AGTATTGCTG CTGCTATATC 
CGCTGCCCCT GCTGTCCTAC CCGCTGTTGC TGCCCTGAGG AAGCCCTGGC CCGCCACCGC 
TACATGAAGC AGGTTCAGGC CCTAGGTCCT CAGATGATGG AAAAACCCCT GTACTGGGGG 
GCGGACAGGA GCTCCCAAGT TTCATCTTAT GCAATGAACC CGCTGCTGCA GCGAGATCTG 
TCCTTACAGT CCAGCCTTCC ACAGATGCCA ATGACCCAGA TGGCTGCTCA CCCTCCGGTG 
GCTAATGGTG TCCTGGAATA TTTGGAGAAA GAATTGCGGA ACCTCAACCC AGCCCAACCT 
CTGCCTGCGG ATCTCAGAGC CAAATCTGGC CACCCTTGCA GCATGCTCTC CTCCCTGGGC 
TCCGCAGAGG TTGTGGAACG CAGAGTCATC CACCTGCCCC CACTAATCAG AGACCCACCG 
TCCTCCAGGA CCAGCAACCC CTCACACCAG CAGCGGCTCA ATGCTGTTTC TTCCAGACAC 
TGCGATCTGA GTGAGCGCCC GAGGCAGCGC CATCACTCCG ATTTCCTCCG AGAGCTCCAG 
GACCAGGGGA TGAGACCCTG GGCCCCGGGG AGAGGGGAGC TGGACCCCCA TTGGAGTGGG 
AGACACCACC GCTCTAGGCC CAGCGAGTCA TCCATGCCTT GGTCAGACTG GGACAGCCTG 
AGCGAATGTC CCTCATCCAG TGAGGCTCCT TGGCCCCCCA GACGACCAGA GCCCAGGGAA 
GGCGCCCAGA GACGTGAGAG ACGCAGGCAT CGCAGCTACT CGCCTCCTCT ACCCTCGGGC 
CCCAGCTCTT GGAGCTCTGA AGAGGAGAAA GAGTCGCTGC CCAGGAACTG GGGTGCCCAG 
CGACGTCACC ATCACCGCCG CCGCCGCTCA CAGTCTCCAA ACTGGCCTGA GGAGAAGCCG 
CCCAGCTACC GCTCACTGGA TGTGACTCCA GGAGAGAGAG AGCTCCCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598870.1
CDS	183..1733
Translation	MGCGLLAAGLLLFTWLPAGCLSLLVTVQHTERYVTLFASVTLKCDYTTSAQLQDVVVTWRFKSFCKDPIFDYFSASYQAALSLGQDPSNDCSDNQREVRIVAQRRGQSEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPTRCCCPEEALARHRYMKQVQALGPQMMEKPLYWGADRSSQVSSYAMNPLLQRDLSLQSSLPQMPMTQMAAHPPVANGVLEYLEKELRNLNPAQPLPADLRAKSGHPCSMLSSLGSAEVVERRVIHLPPLIRDPPSSRTSNPSHQQRLNAVSSRHCDLSERPRQRHHSDFLRELQDQGMRPWAPGRGELDPHWSGRHHRSRPSESSMPWSDWDSLSECPSSSEAPWPPRRPEPREGAQRRERRRHRSYSPPLPSGPSSWSSEEEKESLPRNWGAQRRHHHRRRRSQSPNWPEEKPPSYRSLDVTPGERELP

Target ORF information:

RefSeq Version	NM_134109.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134109.2

ORF Insert Sequence:

ATGGGCTGCG GATTGCTCGC TGCTGGCCTG CTCCTCTTCA CCTGGCTCCC AGCAGGGTGT 
CTGTCCTTGC TAGTCACAGT CCAGCACACA GAACGCTATG TTACTCTGTT TGCCTCCGTT 
ACCCTCAAGT GTGACTACAC CACCTCTGCC CAGCTCCAGG ACGTGGTTGT GACATGGCGC 
TTCAAGTCCT TCTGCAAGGA TCCCATCTTT GACTACTTCT CTGCCTCATA CCAGGCAGCT 
TTGTCCCTGG GCCAGGACCC CTCCAATGAC TGTAGTGACA ATCAGAGGGA AGTTCGCATC 
GTGGCGCAGC GGCGTGGGCA GAGTGAGCCC GTGCTGGGGG TGGATTACCG GCAACGCAAG 
ATCACCATCC AGAACCGAGC AGATCTTGTG ATTAATGAAG TGATGTGGTG GGATCATGGA 
GTATACTATT GTACCATCGA GGCTCCAGGA GACACGTCAG GAGACCCAGA TAAGGAGGTG 
AAGCTCATTG TCCTGCATTG GCTGACAGTG ATTTTCATCA TTCTTGGAGC CCTCCTACTC 
CTGCTGCTGA TTGGTGTATG CTGGTGCCAG TGTTGTCCGC AGTATTGCTG CTGCTATATC 
CGCTGCCCCT GCTGTCCTAC CCGCTGTTGC TGCCCTGAGG AAGCCCTGGC CCGCCACCGC 
TACATGAAGC AGGTTCAGGC CCTAGGTCCT CAGATGATGG AAAAACCCCT GTACTGGGGG 
GCGGACAGGA GCTCCCAAGT TTCATCTTAT GCAATGAACC CGCTGCTGCA GCGAGATCTG 
TCCTTACAGT CCAGCCTTCC ACAGATGCCA ATGACCCAGA TGGCTGCTCA CCCTCCGGTG 
GCTAATGGTG TCCTGGAATA TTTGGAGAAA GAATTGCGGA ACCTCAACCC AGCCCAACCT 
CTGCCTGCGG ATCTCAGAGC CAAATCTGGC CACCCTTGCA GCATGCTCTC CTCCCTGGGC 
TCCGCAGAGG TTGTGGAACG CAGAGTCATC CACCTGCCCC CACTAATCAG AGACCCACCG 
TCCTCCAGGA CCAGCAACCC CTCACACCAG CAGCGGCTCA ATGCTGTTTC TTCCAGACAC 
TGCGATCTGA GTGAGCGCCC GAGGCAGCGC CATCACTCCG ATTTCCTCCG AGAGCTCCAG 
GACCAGGGGA TGAGACCCTG GGCCCCGGGG AGAGGGGAGC TGGACCCCCA TTGGAGTGGG 
AGACACCACC GCTCTAGGCC CAGCGAGTCA TCCATGCCTT GGTCAGACTG GGACAGCCTG 
AGCGAATGTC CCTCATCCAG TGAGGCTCCT TGGCCCCCCA GACGACCAGA GCCCAGGGAA 
GGCGCCCAGA GACGTGAGAG ACGCAGGCAT CGCAGCTACT CGCCTCCTCT ACCCTCGGGC 
CCCAGCTCTT GGAGCTCTGA AGAGGAGAAA GAGTCGCTGC CCAGGAACTG GGGTGCCCAG 
CGACGTCACC ATCACCGCCG CCGCCGCTCA CAGTCTCCAA ACTGGCCTGA GGAGAAGCCG 
CCCAGCTACC GCTCACTGGA TGTGACTCCA GGAGAGAGAG AGCTCCCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ildr1 ( NM_001285788.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001272717.1 Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu17300
Clone ID Related Accession (Same CDS sequence)	NM_001285788.1
Accession Version	NM_001285788.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1614bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Mus musculus(house mouse)
Product	immunoglobulin-like domain-containing receptor 1 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK136284.1 and AC117662.13. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK136284.1, AK035504.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTGCG GATTGCTCGC TGCTGGCCTG CTCCTCTTCA CCTGGCTCCC AGCAGGGTGT 
CTGTCCTTGC TAGTCACAGT CCAGCACACA GAACGCTATG TTACTCTGTT TGCCTCCGTT 
ACCCTCAAGT GTGACTACAC CACCTCTGCC CAGCTCCAGG ACGTGGTTGT GACATGGCGC 
TTCAAGTCCT TCTGCAAGGA TCCCATCTTT GACTACTTCT CTGCCTCATA CCAGGCAGCT 
TTGTCCCTGG GCCAGGACCC CTCCAATGAC TGTAGTGACA ATCAGAGGGA AGTTCGCATC 
GTGGCGCAGC GGCGTGGGCA GAGTGAGCCC GTGCTGGGGG TGGATTACCG GCAACGCAAG 
ATCACCATCC AGAACCGAGC AGATCTTGTG ATTAATGAAG TGATGTGGTG GGATCATGGA 
GTATACTATT GTACCATCGA GGCTCCAGGA GACACGTCAG GAGACCCAGA TAAGGAGGTG 
AAGCTCATTG TCCTGCATTG GCTGACAGTG ATTTTCATCA TTCTTGGAGC CCTCCTACTC 
CTGCTGCTGA TTGGTGTATG CTGGTGCCAG TGTTGTCCGC AGTATTGCTG CTGCTATATC 
CGCTGCCCCT GCTGTCCTAC CCGCTGTTGC TGCCCTGAGG AAGCCCTGGC CCGCCACCGC 
TACATGAAGC AGGTTCAGGC CCTAGGTCCT CAGATGATGG AAAAACCCCT GTACTGGGGG 
GCGGACAGGA GCTCCCAAGT TTCATCTTAT GCAATGAACC CGCTGCTGCA GCGAGATCTG 
TCCTTACAGT CCAGCCTTCC ACAGATGCCA ATGACCCAGA TGGCTGCTCA CCCTCCGGTG 
GCTAATGGTG TCCTGGAATA TTTGGAGAAA GAATTGCGGA ACCTCAACCC AGCCCAACCT 
CTGCCTGCGG ATCTCAGAGC CAAATCTGGC CACCCTTGCA GCATGCTCTC CTCCCTGGGC 
TCCGCAGAGG TTGTGGAACG CAGAGTCATC CACCTGCCCC CACTAATCAG AGACCCACCG 
TCCTCCAGGA CCAGCAACCC CTCACACCAG CAGCGGCTCA ATGCTGTTTC TTCCAGACAC 
TGCGATCTGA GTGAGCGCCC GAGGCAGCGC CATCACTCCG ATTTCCTCCG AGAGCTCCAG 
GACCAGGGGA TGAGACCCTG GGCCCCGGGG AGAGGGGAGC TGGACCCCCA TTGGAGTGGG 
AGACACCACC GCTCTAGGCC CAGCGAGTCA TCCATGCCTT GGTCAGACTG GGACAGCCTG 
AGCGAATGTC CCTCATCCAG TGAGGCTCCT TGGCCCCCCA GACGACCAGA GCCCAGGGAA 
GGCGCCCAGA GACGTGAGAG ACGCAGGCAT CGCAGCTACT CGCCTCCTCT ACCCTCGGGC 
CCCAGCTCTT GGAGCTCTGA AGAGGAGAAA GAGTCGCTGC CCAGGAACTG GGGTGCCCAG 
CGACGTCACC ATCACCGCCG CCGCCGCTCA CAGTCTCCAA ACTGGCCTGA GGAGAAGCCG 
CCCAGCTACC GCTCACTGGA TGTGACTCCA GGCAAGAACA ACAGGAAAAA AGGGAATGTG 
GAGAGGCGCT TGGAGAGAGA GAGCTCCCAT AGTGGACGGA GTGTGGTCAT TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001272717.1
CDS	183..1796
Translation	MGCGLLAAGLLLFTWLPAGCLSLLVTVQHTERYVTLFASVTLKCDYTTSAQLQDVVVTWRFKSFCKDPIFDYFSASYQAALSLGQDPSNDCSDNQREVRIVAQRRGQSEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPTRCCCPEEALARHRYMKQVQALGPQMMEKPLYWGADRSSQVSSYAMNPLLQRDLSLQSSLPQMPMTQMAAHPPVANGVLEYLEKELRNLNPAQPLPADLRAKSGHPCSMLSSLGSAEVVERRVIHLPPLIRDPPSSRTSNPSHQQRLNAVSSRHCDLSERPRQRHHSDFLRELQDQGMRPWAPGRGELDPHWSGRHHRSRPSESSMPWSDWDSLSECPSSSEAPWPPRRPEPREGAQRRERRRHRSYSPPLPSGPSSWSSEEEKESLPRNWGAQRRHHHRRRRSQSPNWPEEKPPSYRSLDVTPGKNNRKKGNVERRLERESSHSGRSVVI

Target ORF information:

RefSeq Version	NM_001285788.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001285788.1

ORF Insert Sequence:

ATGGGCTGCG GATTGCTCGC TGCTGGCCTG CTCCTCTTCA CCTGGCTCCC AGCAGGGTGT 
CTGTCCTTGC TAGTCACAGT CCAGCACACA GAACGCTATG TTACTCTGTT TGCCTCCGTT 
ACCCTCAAGT GTGACTACAC CACCTCTGCC CAGCTCCAGG ACGTGGTTGT GACATGGCGC 
TTCAAGTCCT TCTGCAAGGA TCCCATCTTT GACTACTTCT CTGCCTCATA CCAGGCAGCT 
TTGTCCCTGG GCCAGGACCC CTCCAATGAC TGTAGTGACA ATCAGAGGGA AGTTCGCATC 
GTGGCGCAGC GGCGTGGGCA GAGTGAGCCC GTGCTGGGGG TGGATTACCG GCAACGCAAG 
ATCACCATCC AGAACCGAGC AGATCTTGTG ATTAATGAAG TGATGTGGTG GGATCATGGA 
GTATACTATT GTACCATCGA GGCTCCAGGA GACACGTCAG GAGACCCAGA TAAGGAGGTG 
AAGCTCATTG TCCTGCATTG GCTGACAGTG ATTTTCATCA TTCTTGGAGC CCTCCTACTC 
CTGCTGCTGA TTGGTGTATG CTGGTGCCAG TGTTGTCCGC AGTATTGCTG CTGCTATATC 
CGCTGCCCCT GCTGTCCTAC CCGCTGTTGC TGCCCTGAGG AAGCCCTGGC CCGCCACCGC 
TACATGAAGC AGGTTCAGGC CCTAGGTCCT CAGATGATGG AAAAACCCCT GTACTGGGGG 
GCGGACAGGA GCTCCCAAGT TTCATCTTAT GCAATGAACC CGCTGCTGCA GCGAGATCTG 
TCCTTACAGT CCAGCCTTCC ACAGATGCCA ATGACCCAGA TGGCTGCTCA CCCTCCGGTG 
GCTAATGGTG TCCTGGAATA TTTGGAGAAA GAATTGCGGA ACCTCAACCC AGCCCAACCT 
CTGCCTGCGG ATCTCAGAGC CAAATCTGGC CACCCTTGCA GCATGCTCTC CTCCCTGGGC 
TCCGCAGAGG TTGTGGAACG CAGAGTCATC CACCTGCCCC CACTAATCAG AGACCCACCG 
TCCTCCAGGA CCAGCAACCC CTCACACCAG CAGCGGCTCA ATGCTGTTTC TTCCAGACAC 
TGCGATCTGA GTGAGCGCCC GAGGCAGCGC CATCACTCCG ATTTCCTCCG AGAGCTCCAG 
GACCAGGGGA TGAGACCCTG GGCCCCGGGG AGAGGGGAGC TGGACCCCCA TTGGAGTGGG 
AGACACCACC GCTCTAGGCC CAGCGAGTCA TCCATGCCTT GGTCAGACTG GGACAGCCTG 
AGCGAATGTC CCTCATCCAG TGAGGCTCCT TGGCCCCCCA GACGACCAGA GCCCAGGGAA 
GGCGCCCAGA GACGTGAGAG ACGCAGGCAT CGCAGCTACT CGCCTCCTCT ACCCTCGGGC 
CCCAGCTCTT GGAGCTCTGA AGAGGAGAAA GAGTCGCTGC CCAGGAACTG GGGTGCCCAG 
CGACGTCACC ATCACCGCCG CCGCCGCTCA CAGTCTCCAA ACTGGCCTGA GGAGAAGCCG 
CCCAGCTACC GCTCACTGGA TGTGACTCCA GGCAAGAACA ACAGGAAAAA AGGGAATGTG 
GAGAGGCGCT TGGAGAGAGA GAGCTCCCAT AGTGGACGGA GTGTGGTCAT TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ildr1 ( XM_006521674.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521737.1 Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51789
Clone ID Related Accession (Same CDS sequence)	XM_006521674.3 , XM_006521674.4
Accession Version	XM_006521674.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	immunoglobulin-like domain-containing receptor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006521674.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGGACC TCAAGTCAGC CACCATTGTT TGGAAGACCC CAGCTCGCTG TCACACTTCG 
GCATACCAGG CAGCTTTGTC CCTGGGCCAG GACCCCTCCA ATGACTGTAG TGACAATCAG 
AGGGAAGTTC GCATCGTGGC GCAGCGGCGT GGGCAGAGTG AGCCCGTGCT GGGGGTGGAT 
TACCGGCAAC GCAAGATCAC CATCCAGAAC CGAGCAGATC TTGTGATTAA TGAAGTGATG 
TGGTGGGATC ATGGAGTATA CTATTGTACC ATCGAGGCTC CAGGAGACAC GTCAGGAGAC 
CCAGATAAGG AGGTGAAGCT CATTGTCCTG CATTGGCTGA CAGTGATTTT CATCATTCTT 
GGAGCCCTCC TACTCCTGCT GCTGATTGGT GTATGCTGGT GCCAGTGTTG TCCGCAGTAT 
TGCTGCTGCT ATATCCGCTG CCCCTGCTGT CCTACCCGCT GTTGCTGCCC TGAGGAAGCC 
CTGGCCCGCC ACCGCTACAT GAAGCAGGTT CAGGCCCTAG GTCCTCAGAT GATGGAAAAA 
CCCCTGTACT GGGGGGCGGA CAGGAGCTCC CAAGTTTCAT CTTATGCAAT GAACCCGCTG 
CTGCAGCGAG ATCTGTCCTT ACAGTCCAGC CTTCCACAGA TGCCAATGAC CCAGATGGCT 
GCTCACCCTC CGGTGGCTAA TGGTGTCCTG GAATATTTGG AGAAAGAATT GCGGAACCTC 
AACCCAGCCC AACCTCTGCC TGCGGATCTC AGAGCCAAAT CTGGCCACCC TTGCAGCATG 
CTCTCCTCCC TGGGCTCCGC AGAGGTTGTG GAACGCAGAG TCATCCACCT GCCCCCACTA 
ATCAGAGACC CACCGTCCTC CAGGACCAGC AACCCCTCAC ACCAGCAGCG GCTCAATGCT 
GTTTCTTCCA GACACTGCGA TCTGAGTGAG CGCCCGAGGC AGCGCCATCA CTCCGATTTC 
CTCCGAGAGC TCCAGGACCA GGGGATGAGA CCCTGGGCCC CGGGGAGAGG GGAGCTGGAC 
CCCCATTGGA GTGGGAGACA CCACCGCTCT AGGCCCAGCG AGTCATCCAT GCCTTGGTCA 
GACTGGGACA GCCTGAGCGA ATGTCCCTCA TCCAGTGAGG CTCCTTGGCC CCCCAGACGA 
CCAGAGCCCA GGGAAGGCGC CCAGAGACGT GAGAGACGCA GGCATCGCAG CTACTCGCCT 
CCTCTACCCT CGGGCCCCAG CTCTTGGAGC TCTGAAGAGG AGAAAGAGTC GCTGCCCAGG 
AACTGGGGTG CCCAGCGACG TCACCATCAC CGCCGCCGCC GCTCACAGTC TCCAAACTGG 
CCTGAGGAGA AGCCGCCCAG CTACCGCTCA CTGGATGTGA CTCCAGGCAA GAACAACAGG 
AAAAAAGGGA ATGTGGAGAG GCGCTTGGAG AGAGAGAGCT CCCATAGTGG ACGGAGTGTG 
GTCATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521737.1
CDS	41..1489
Translation	MWDLKSATIVWKTPARCHTSAYQAALSLGQDPSNDCSDNQREVRIVAQRRGQSEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPTRCCCPEEALARHRYMKQVQALGPQMMEKPLYWGADRSSQVSSYAMNPLLQRDLSLQSSLPQMPMTQMAAHPPVANGVLEYLEKELRNLNPAQPLPADLRAKSGHPCSMLSSLGSAEVVERRVIHLPPLIRDPPSSRTSNPSHQQRLNAVSSRHCDLSERPRQRHHSDFLRELQDQGMRPWAPGRGELDPHWSGRHHRSRPSESSMPWSDWDSLSECPSSSEAPWPPRRPEPREGAQRRERRRHRSYSPPLPSGPSSWSSEEEKESLPRNWGAQRRHHHRRRRSQSPNWPEEKPPSYRSLDVTPGKNNRKKGNVERRLERESSHSGRSVVI

Target ORF information:

RefSeq Version	XM_006521674.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521674.3

ORF Insert Sequence:

ATGTGGGACC TCAAGTCAGC CACCATTGTT TGGAAGACCC CAGCTCGCTG TCACACTTCG 
GCATACCAGG CAGCTTTGTC CCTGGGCCAG GACCCCTCCA ATGACTGTAG TGACAATCAG 
AGGGAAGTTC GCATCGTGGC GCAGCGGCGT GGGCAGAGTG AGCCCGTGCT GGGGGTGGAT 
TACCGGCAAC GCAAGATCAC CATCCAGAAC CGAGCAGATC TTGTGATTAA TGAAGTGATG 
TGGTGGGATC ATGGAGTATA CTATTGTACC ATCGAGGCTC CAGGAGACAC GTCAGGAGAC 
CCAGATAAGG AGGTGAAGCT CATTGTCCTG CATTGGCTGA CAGTGATTTT CATCATTCTT 
GGAGCCCTCC TACTCCTGCT GCTGATTGGT GTATGCTGGT GCCAGTGTTG TCCGCAGTAT 
TGCTGCTGCT ATATCCGCTG CCCCTGCTGT CCTACCCGCT GTTGCTGCCC TGAGGAAGCC 
CTGGCCCGCC ACCGCTACAT GAAGCAGGTT CAGGCCCTAG GTCCTCAGAT GATGGAAAAA 
CCCCTGTACT GGGGGGCGGA CAGGAGCTCC CAAGTTTCAT CTTATGCAAT GAACCCGCTG 
CTGCAGCGAG ATCTGTCCTT ACAGTCCAGC CTTCCACAGA TGCCAATGAC CCAGATGGCT 
GCTCACCCTC CGGTGGCTAA TGGTGTCCTG GAATATTTGG AGAAAGAATT GCGGAACCTC 
AACCCAGCCC AACCTCTGCC TGCGGATCTC AGAGCCAAAT CTGGCCACCC TTGCAGCATG 
CTCTCCTCCC TGGGCTCCGC AGAGGTTGTG GAACGCAGAG TCATCCACCT GCCCCCACTA 
ATCAGAGACC CACCGTCCTC CAGGACCAGC AACCCCTCAC ACCAGCAGCG GCTCAATGCT 
GTTTCTTCCA GACACTGCGA TCTGAGTGAG CGCCCGAGGC AGCGCCATCA CTCCGATTTC 
CTCCGAGAGC TCCAGGACCA GGGGATGAGA CCCTGGGCCC CGGGGAGAGG GGAGCTGGAC 
CCCCATTGGA GTGGGAGACA CCACCGCTCT AGGCCCAGCG AGTCATCCAT GCCTTGGTCA 
GACTGGGACA GCCTGAGCGA ATGTCCCTCA TCCAGTGAGG CTCCTTGGCC CCCCAGACGA 
CCAGAGCCCA GGGAAGGCGC CCAGAGACGT GAGAGACGCA GGCATCGCAG CTACTCGCCT 
CCTCTACCCT CGGGCCCCAG CTCTTGGAGC TCTGAAGAGG AGAAAGAGTC GCTGCCCAGG 
AACTGGGGTG CCCAGCGACG TCACCATCAC CGCCGCCGCC GCTCACAGTC TCCAAACTGG 
CCTGAGGAGA AGCCGCCCAG CTACCGCTCA CTGGATGTGA CTCCAGGCAA GAACAACAGG 
AAAAAAGGGA ATGTGGAGAG GCGCTTGGAG AGAGAGAGCT CCCATAGTGG ACGGAGTGTG 
GTCATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ildr1 ( NM_001285791.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001272720.1 Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 3, mRNA.

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CloneID	OMu17231
Clone ID Related Accession (Same CDS sequence)	NM_001285791.1
Accession Version	NM_001285791.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Mus musculus(house mouse)
Product	immunoglobulin-like domain-containing receptor 1 isoform 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117662.13. Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region compared to variant 1. Theencoded isoform (3) is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC057644.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTGCG GATTGCTCGC TGCTGGCCTG CTCCTCTTCA CCTGGCTCCC AGCAGGGTGT 
CTGTCCTTGC TAGTCACAGT CCAGCACACA GAACGCTATG TTACTCTGTT TGCCTCCGTT 
ACCCTCAAGT GTGACTACAC CACCTCTGCC CAGCTCCAGG ACGTGGTTGT GACATGGCGC 
TTCAAGTCCT TCTGCAAGGA TCCCATCTTT GACTACTTCT CTGCCTCATA CCAGGCAGCT 
TTGTCCCTGG GCCAGGACCC CTCCAATGAC TGTAGTGACA ATCAGAGGGA AGTTCGCATC 
GTGGCGCAGC GGCGTGGGCA GAGTGAGCCC GTGCTGGGGG TGGATTACCG GCAACGCAAG 
ATCACCATCC AGAACCGAGC AGATCTTGTG ATTAATGAAG TGATGTGGTG GGATCATGGA 
GTATACTATT GTACCATCGA GGCTCCAGGA GACACGTCAG GAGACCCAGA TAAGGAGGTG 
AAGCTCATTG TCCTGCATTG GCTGACAGTG ATTTTCATCA TTCTTGGAGC CCTCCTACTC 
CTGCTGCTGA TTGGTGTATG CTGGTGCCAG TGTTGTCCGC AGTATTGCTG CTGCTATATC 
CGCTGCCCCT GCTGTCCTAC CCGCTGTTGC TGCCCTGAGG AAGATCTGTC CTTACAGTCC 
AGCCTTCCAC AGATGCCAAT GACCCAGATG GCTGCTCACC CTCCGGTGGC TAATGGTGTC 
CTGGAATATT TGGAGAAAGA ATTGCGGAAC CTCAACCCAG CCCAACCTCT GCCTGCGGAT 
CTCAGAGCCA AATCTGGCCA CCCTTGCAGC ATGCTCTCCT CCCTGGGCTC CGCAGAGGTT 
GTGGAACGCA GAGTCATCCA CCTGCCCCCA CTAATCAGAG ACCCACCGTC CTCCAGGACC 
AGCAACCCCT CACACCAGCA GCGGCTCAAT GCTGTTTCTT CCAGACACTG CGATCTGAGT 
GAGCGCCCGA GGCAGCGCCA TCACTCCGAT TTCCTCCGAG AGCTCCAGGA CCAGGGGATG 
AGACCCTGGG CCCCGGGGAG AGGGGAGCTG GACCCCCATT GGAGTGGGAG ACACCACCGC 
TCTAGGCCCA GCGAGTCATC CATGCCTTGG TCAGACTGGG ACAGCCTGAG CGAATGTCCC 
TCATCCAGTG AGGCTCCTTG GCCCCCCAGA CGACCAGAGC CCAGGGAAGG CGCCCAGAGA 
CGTGAGAGAC GCAGGCATCG CAGCTACTCG CCTCCTCTAC CCTCGGGCCC CAGCTCTTGG 
AGCTCTGAAG AGGAGAAAGA GTCGCTGCCC AGGAACTGGG GTGCCCAGCG ACGTCACCAT 
CACCGCCGCC GCCGCTCACA GTCTCCAAAC TGGCCTGAGG AGAAGCCGCC CAGCTACCGC 
TCACTGGATG TGACTCCAGG CAAGAACAAC AGGAAAAAAG GGAATGTGGA GAGGCGCTTG 
GAGAGAGAGA GCTCCCATAG TGGACGGAGT GTGGTCATTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001272720.1
CDS	183..1664
Translation	MGCGLLAAGLLLFTWLPAGCLSLLVTVQHTERYVTLFASVTLKCDYTTSAQLQDVVVTWRFKSFCKDPIFDYFSASYQAALSLGQDPSNDCSDNQREVRIVAQRRGQSEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPTRCCCPEEDLSLQSSLPQMPMTQMAAHPPVANGVLEYLEKELRNLNPAQPLPADLRAKSGHPCSMLSSLGSAEVVERRVIHLPPLIRDPPSSRTSNPSHQQRLNAVSSRHCDLSERPRQRHHSDFLRELQDQGMRPWAPGRGELDPHWSGRHHRSRPSESSMPWSDWDSLSECPSSSEAPWPPRRPEPREGAQRRERRRHRSYSPPLPSGPSSWSSEEEKESLPRNWGAQRRHHHRRRRSQSPNWPEEKPPSYRSLDVTPGKNNRKKGNVERRLERESSHSGRSVVI

Target ORF information:

RefSeq Version	NM_001285791.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001285791.1

ORF Insert Sequence:

ATGGGCTGCG GATTGCTCGC TGCTGGCCTG CTCCTCTTCA CCTGGCTCCC AGCAGGGTGT 
CTGTCCTTGC TAGTCACAGT CCAGCACACA GAACGCTATG TTACTCTGTT TGCCTCCGTT 
ACCCTCAAGT GTGACTACAC CACCTCTGCC CAGCTCCAGG ACGTGGTTGT GACATGGCGC 
TTCAAGTCCT TCTGCAAGGA TCCCATCTTT GACTACTTCT CTGCCTCATA CCAGGCAGCT 
TTGTCCCTGG GCCAGGACCC CTCCAATGAC TGTAGTGACA ATCAGAGGGA AGTTCGCATC 
GTGGCGCAGC GGCGTGGGCA GAGTGAGCCC GTGCTGGGGG TGGATTACCG GCAACGCAAG 
ATCACCATCC AGAACCGAGC AGATCTTGTG ATTAATGAAG TGATGTGGTG GGATCATGGA 
GTATACTATT GTACCATCGA GGCTCCAGGA GACACGTCAG GAGACCCAGA TAAGGAGGTG 
AAGCTCATTG TCCTGCATTG GCTGACAGTG ATTTTCATCA TTCTTGGAGC CCTCCTACTC 
CTGCTGCTGA TTGGTGTATG CTGGTGCCAG TGTTGTCCGC AGTATTGCTG CTGCTATATC 
CGCTGCCCCT GCTGTCCTAC CCGCTGTTGC TGCCCTGAGG AAGATCTGTC CTTACAGTCC 
AGCCTTCCAC AGATGCCAAT GACCCAGATG GCTGCTCACC CTCCGGTGGC TAATGGTGTC 
CTGGAATATT TGGAGAAAGA ATTGCGGAAC CTCAACCCAG CCCAACCTCT GCCTGCGGAT 
CTCAGAGCCA AATCTGGCCA CCCTTGCAGC ATGCTCTCCT CCCTGGGCTC CGCAGAGGTT 
GTGGAACGCA GAGTCATCCA CCTGCCCCCA CTAATCAGAG ACCCACCGTC CTCCAGGACC 
AGCAACCCCT CACACCAGCA GCGGCTCAAT GCTGTTTCTT CCAGACACTG CGATCTGAGT 
GAGCGCCCGA GGCAGCGCCA TCACTCCGAT TTCCTCCGAG AGCTCCAGGA CCAGGGGATG 
AGACCCTGGG CCCCGGGGAG AGGGGAGCTG GACCCCCATT GGAGTGGGAG ACACCACCGC 
TCTAGGCCCA GCGAGTCATC CATGCCTTGG TCAGACTGGG ACAGCCTGAG CGAATGTCCC 
TCATCCAGTG AGGCTCCTTG GCCCCCCAGA CGACCAGAGC CCAGGGAAGG CGCCCAGAGA 
CGTGAGAGAC GCAGGCATCG CAGCTACTCG CCTCCTCTAC CCTCGGGCCC CAGCTCTTGG 
AGCTCTGAAG AGGAGAAAGA GTCGCTGCCC AGGAACTGGG GTGCCCAGCG ACGTCACCAT 
CACCGCCGCC GCCGCTCACA GTCTCCAAAC TGGCCTGAGG AGAAGCCGCC CAGCTACCGC 
TCACTGGATG TGACTCCAGG CAAGAACAAC AGGAAAAAAG GGAATGTGGA GAGGCGCTTG 
GAGAGAGAGA GCTCCCATAG TGGACGGAGT GTGGTCATTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ildr1 ( XM_006521674.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521737.1 Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant X1, mRNA.

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CloneID	OMu51789
Clone ID Related Accession (Same CDS sequence)	XM_006521674.3 , XM_006521674.4
Accession Version	XM_006521674.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	immunoglobulin-like domain-containing receptor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006521674.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGGACC TCAAGTCAGC CACCATTGTT TGGAAGACCC CAGCTCGCTG TCACACTTCG 
GCATACCAGG CAGCTTTGTC CCTGGGCCAG GACCCCTCCA ATGACTGTAG TGACAATCAG 
AGGGAAGTTC GCATCGTGGC GCAGCGGCGT GGGCAGAGTG AGCCCGTGCT GGGGGTGGAT 
TACCGGCAAC GCAAGATCAC CATCCAGAAC CGAGCAGATC TTGTGATTAA TGAAGTGATG 
TGGTGGGATC ATGGAGTATA CTATTGTACC ATCGAGGCTC CAGGAGACAC GTCAGGAGAC 
CCAGATAAGG AGGTGAAGCT CATTGTCCTG CATTGGCTGA CAGTGATTTT CATCATTCTT 
GGAGCCCTCC TACTCCTGCT GCTGATTGGT GTATGCTGGT GCCAGTGTTG TCCGCAGTAT 
TGCTGCTGCT ATATCCGCTG CCCCTGCTGT CCTACCCGCT GTTGCTGCCC TGAGGAAGCC 
CTGGCCCGCC ACCGCTACAT GAAGCAGGTT CAGGCCCTAG GTCCTCAGAT GATGGAAAAA 
CCCCTGTACT GGGGGGCGGA CAGGAGCTCC CAAGTTTCAT CTTATGCAAT GAACCCGCTG 
CTGCAGCGAG ATCTGTCCTT ACAGTCCAGC CTTCCACAGA TGCCAATGAC CCAGATGGCT 
GCTCACCCTC CGGTGGCTAA TGGTGTCCTG GAATATTTGG AGAAAGAATT GCGGAACCTC 
AACCCAGCCC AACCTCTGCC TGCGGATCTC AGAGCCAAAT CTGGCCACCC TTGCAGCATG 
CTCTCCTCCC TGGGCTCCGC AGAGGTTGTG GAACGCAGAG TCATCCACCT GCCCCCACTA 
ATCAGAGACC CACCGTCCTC CAGGACCAGC AACCCCTCAC ACCAGCAGCG GCTCAATGCT 
GTTTCTTCCA GACACTGCGA TCTGAGTGAG CGCCCGAGGC AGCGCCATCA CTCCGATTTC 
CTCCGAGAGC TCCAGGACCA GGGGATGAGA CCCTGGGCCC CGGGGAGAGG GGAGCTGGAC 
CCCCATTGGA GTGGGAGACA CCACCGCTCT AGGCCCAGCG AGTCATCCAT GCCTTGGTCA 
GACTGGGACA GCCTGAGCGA ATGTCCCTCA TCCAGTGAGG CTCCTTGGCC CCCCAGACGA 
CCAGAGCCCA GGGAAGGCGC CCAGAGACGT GAGAGACGCA GGCATCGCAG CTACTCGCCT 
CCTCTACCCT CGGGCCCCAG CTCTTGGAGC TCTGAAGAGG AGAAAGAGTC GCTGCCCAGG 
AACTGGGGTG CCCAGCGACG TCACCATCAC CGCCGCCGCC GCTCACAGTC TCCAAACTGG 
CCTGAGGAGA AGCCGCCCAG CTACCGCTCA CTGGATGTGA CTCCAGGCAA GAACAACAGG 
AAAAAAGGGA ATGTGGAGAG GCGCTTGGAG AGAGAGAGCT CCCATAGTGG ACGGAGTGTG 
GTCATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521737.1
CDS	40..1488
Translation	MWDLKSATIVWKTPARCHTSAYQAALSLGQDPSNDCSDNQREVRIVAQRRGQSEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPTRCCCPEEALARHRYMKQVQALGPQMMEKPLYWGADRSSQVSSYAMNPLLQRDLSLQSSLPQMPMTQMAAHPPVANGVLEYLEKELRNLNPAQPLPADLRAKSGHPCSMLSSLGSAEVVERRVIHLPPLIRDPPSSRTSNPSHQQRLNAVSSRHCDLSERPRQRHHSDFLRELQDQGMRPWAPGRGELDPHWSGRHHRSRPSESSMPWSDWDSLSECPSSSEAPWPPRRPEPREGAQRRERRRHRSYSPPLPSGPSSWSSEEEKESLPRNWGAQRRHHHRRRRSQSPNWPEEKPPSYRSLDVTPGKNNRKKGNVERRLERESSHSGRSVVI

Target ORF information:

RefSeq Version	XM_006521674.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521674.4

ORF Insert Sequence:

ATGTGGGACC TCAAGTCAGC CACCATTGTT TGGAAGACCC CAGCTCGCTG TCACACTTCG 
GCATACCAGG CAGCTTTGTC CCTGGGCCAG GACCCCTCCA ATGACTGTAG TGACAATCAG 
AGGGAAGTTC GCATCGTGGC GCAGCGGCGT GGGCAGAGTG AGCCCGTGCT GGGGGTGGAT 
TACCGGCAAC GCAAGATCAC CATCCAGAAC CGAGCAGATC TTGTGATTAA TGAAGTGATG 
TGGTGGGATC ATGGAGTATA CTATTGTACC ATCGAGGCTC CAGGAGACAC GTCAGGAGAC 
CCAGATAAGG AGGTGAAGCT CATTGTCCTG CATTGGCTGA CAGTGATTTT CATCATTCTT 
GGAGCCCTCC TACTCCTGCT GCTGATTGGT GTATGCTGGT GCCAGTGTTG TCCGCAGTAT 
TGCTGCTGCT ATATCCGCTG CCCCTGCTGT CCTACCCGCT GTTGCTGCCC TGAGGAAGCC 
CTGGCCCGCC ACCGCTACAT GAAGCAGGTT CAGGCCCTAG GTCCTCAGAT GATGGAAAAA 
CCCCTGTACT GGGGGGCGGA CAGGAGCTCC CAAGTTTCAT CTTATGCAAT GAACCCGCTG 
CTGCAGCGAG ATCTGTCCTT ACAGTCCAGC CTTCCACAGA TGCCAATGAC CCAGATGGCT 
GCTCACCCTC CGGTGGCTAA TGGTGTCCTG GAATATTTGG AGAAAGAATT GCGGAACCTC 
AACCCAGCCC AACCTCTGCC TGCGGATCTC AGAGCCAAAT CTGGCCACCC TTGCAGCATG 
CTCTCCTCCC TGGGCTCCGC AGAGGTTGTG GAACGCAGAG TCATCCACCT GCCCCCACTA 
ATCAGAGACC CACCGTCCTC CAGGACCAGC AACCCCTCAC ACCAGCAGCG GCTCAATGCT 
GTTTCTTCCA GACACTGCGA TCTGAGTGAG CGCCCGAGGC AGCGCCATCA CTCCGATTTC 
CTCCGAGAGC TCCAGGACCA GGGGATGAGA CCCTGGGCCC CGGGGAGAGG GGAGCTGGAC 
CCCCATTGGA GTGGGAGACA CCACCGCTCT AGGCCCAGCG AGTCATCCAT GCCTTGGTCA 
GACTGGGACA GCCTGAGCGA ATGTCCCTCA TCCAGTGAGG CTCCTTGGCC CCCCAGACGA 
CCAGAGCCCA GGGAAGGCGC CCAGAGACGT GAGAGACGCA GGCATCGCAG CTACTCGCCT 
CCTCTACCCT CGGGCCCCAG CTCTTGGAGC TCTGAAGAGG AGAAAGAGTC GCTGCCCAGG 
AACTGGGGTG CCCAGCGACG TCACCATCAC CGCCGCCGCC GCTCACAGTC TCCAAACTGG 
CCTGAGGAGA AGCCGCCCAG CTACCGCTCA CTGGATGTGA CTCCAGGCAA GAACAACAGG 
AAAAAAGGGA ATGTGGAGAG GCGCTTGGAG AGAGAGAGCT CCCATAGTGG ACGGAGTGTG 
GTCATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ILDR1 is important for paracellular water transport and urine concentration mechanism.
Proceedings of the National Academy of Sciences of the United States of America114(20)5271-5276(2017 May)
Gong Y,Himmerkus N,Sunq A,Milatz S,Merkel C,Bleich M,Hou J

ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42.
Biology open4(4)411-8(2015 Mar)
Sang Q,Li W,Xu Y,Qu R,Xu Z,Feng R,Jin L,He L,Li H,Wang L

ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.
Human molecular genetics24(3)609-24(2015 Feb)
Morozko EL,Nishio A,Ingham NJ,Chandra R,Fitzgerald T,Martelletti E,Borck G,Wilson E,Riordan GP,Wangemann P,Forge A,Steel KP,Liddle RA,Friedman TB,Belyantseva IA

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
PloS one10(3)e0121550(2015)
Gu Z,Imai F,Kim IJ,Fujita H,Katayama Ki,Mori K,Yoshihara Y,Yoshida Y

Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice.
PloS one10(3)e0120674(2015)
Higashi T,Katsuno T,Kitajiri S,Furuse M