Qsox1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Qsox1
Entrez Gene ID	104009
Full Name	quiescin Q6 sulfhydryl oxidase 1
Synonyms	1300003H02Rik,QSOX,Qscn6,SOx,b2b2673Clo
General protein information	Preferred Names quiescin Q6 sulfhydryl oxidase 1 Names sulfhydryl oxidase 1 skin sulfhydryl oxidase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 G3

mRNA and Protein(s)

mRNA	Protein	Name
NM_023268.2	NP_075757.1	sulfhydryl oxidase 1 isoform b precursor
NM_001024945.1	NP_001020116.1	sulfhydryl oxidase 1 isoform a precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	QSOX1	XP_003954475.1
Mus musculus (house mouse)	Qsox1	NP_001020116.1
Rattus norvegicus (Norway rat)	Qsox1	NP_001103368.1
Gallus gallus (chicken)	QSOX1	NP_989456.1
Drosophila melanogaster (fruit fly)	CG4670	NP_610852.1
	QSOX1	XP_001111489.2
Bos taurus (cattle)	QSOX1	NP_001095544.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007491	XP_564767.3
Caenorhabditis elegans (roundworm)	T10H10.2	NP_508419.1
Danio rerio (zebrafish)	qsox1	NP_001121836.1
Homo sapiens (human)	QSOX1	NP_002817.2
Caenorhabditis elegans (roundworm)	F47B7.2	NP_508652.1
Caenorhabditis elegans (roundworm)	F35G2.1	NP_502314.1
Xenopus tropicalis (tropical clawed frog)	qsox1	XP_002937004.1

Gene Ontology
Bibliography

Related articles in PubMed

Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms.
Zhang L, Cheng Q, Zhang L, Wang Y, Merrill GF, Ilani T, Fass D, Arn?r ESJ, Zhang J
Free radical biology & medicine99426-435(2016 10)

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW
Nature521(7553)520-4(2015 May)

QSOX1 inhibits autophagic flux in breast cancer cells.
Poillet L, Pernodet N, Boyer-Guittaut M, Adami P, Borg C, Jouvenot M, Delage-Mourroux R, Despouy G
PloS one9(1)e86641(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms, in particular, by the serum QSOX1.
Title: Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms.

QSOX1 inhibits autophagy in breast cancer cells.
Title: QSOX1 inhibits autophagic flux in breast cancer cells.

crystal structure
Title: The dynamic disulphide relay of quiescin sulphydryl oxidase.

In seminiferous tubules, where a high level of expression was noticed, QSOX might play an important physiological role in sperm function and serve as a marker for the diagnosis of male infertility.
Title: Cell-specific localization of the sulphydryl oxidase QSOX in rat peripheral tissues.

cloned skin SOx cDNA and characterized it as one of the disulfide (S-S) cross-linking enzymes
Title: Sulfhydryl oxidase (SOx) from mouse epidermis: molecular cloning, nucleotide sequence, and expression of recombinant protein in the cultured cells.

The following Qsox1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Qsox1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01097	NM_023268.2 Latest version!	Mus musculus quiescin Q6 sulfhydryl oxidase 1 (Qsox1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$335.30 $479.00
OMu12020	NM_001024945.1 Latest version!	Mus musculus quiescin Q6 sulfhydryl oxidase 1 (Qsox1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$440.30 $629.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Qsox1 ( NM_023268.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_075757.1 Mus musculus quiescin Q6 sulfhydryl oxidase 1 (Qsox1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu01097
Clone ID Related Accession (Same CDS sequence)	NM_023268.2
Accession Version	NM_023268.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	sulfhydryl oxidase 1 isoform b precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY334148.1, AK083938.1, AB044284.1 and CK625426.1. On Jun 22, 2005 this sequence version replaced NM_023268.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1. The resulting protein (isoform b) is shorter and has a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK004880.1, AK170449.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGAGGAGGT GCGGCCGCCT CTCGGGGCCG CCATCGCTGC TGCTACTACT GCTGCTGCTC 
TCGCCTCTGC TCTTCTCGGG GCCCGGCGCT TACGCGGCCC GGCTCTCAGT GCTCTACTCG 
TCCTCTGACC CGCTGACGCT GCTGGATGCT GATTCGGTGC GTCCCACTGT GCTCGGCTCC 
AGCAGCGCCT GGGCGGTGGA GTTCTTCGCC TCCTGGTGTG GCCACTGCAT CGCCTTCGCC 
CCGACGTGGA AGGAGCTTGC TAACGACGTG AAAGACTGGA GGCCAGCACT CAATCTTGCT 
GTCCTGGACT GTGCTGAGGA GACCAACAGT GCTGTCTGCA GAGAGTTCAA CATCGCTGGC 
TTCCCGACTG TGAGGTTTTT TCAGGCCTTT ACCAAGAACG GTTCTGGAGC GACACTGCCA 
GGTGCTGGCG CTAATGTGCA GACTCTGCGT ATGAGGCTCA TCGATGCTCT GGAGTCCCAC 
CGTGACACAT GGCCCCCAGC CTGTCCACCT CTGGAACCTG CCAAGCTGAA TGATATCGAC 
GGATTCTTTA CAAGAAATAA AGCAGATTAC CTGGCCCTGG TCTTTGAAAG GGAAGACTCC 
TACCTGGGTA GAGAGGTAAC TCTGGACCTG TCCCAGTACC ATGCTGTGGC AGTGCGCAGG 
GTCTTGAATA CAGAGAGTGA CCTGGTGAAC AAGTTTGGCG TCACTGACTT CCCATCTTGT 
TACCTGCTGC TTCGGAATGG CTCTGTCTCC CGAGTGCCTG TGCTGGTGGA GTCCAGGTCT 
TTCTATACAT CCTATCTTCG GGGGCTACCT GGACTGACCA GGGATGCTCC CCCAACCACA 
GCCACCCCAG TCACTGCTGA TAAGATAGCA CCCACAGTGT GGAAGTTTGC AGACCGCTCC 
AAGATCTACA TGGCCGACCT GGAGTCCGCA CTCCACTACA TCTTGCGTGT AGAAGTGGGG 
AAGTTCTCAG TGCTGGAGGG ACAGCGCCTG GTGGCCCTGA AAAAGTTTGT GGCAGTATTG 
GCCAAGTACT TCCCTGGGCA GCCTTTGGTC CAGAACTTCT TGCATTCCAT AAACGACTGG 
CTTCAGAAGC AGCAGAAGAA GAGGATCCCC TACAGTTTCT TCAAAGCTGC TCTGGACAGC 
AGGAAGGAGG ATGCTGTCCT TACTGAGAAG GTGAACTGGG TCGGCTGCCA GGGCAGTGAG 
CCACACTTCC GGGGGTTTCC CTGCTCACTG TGGGTCCTCT TCCACTTCCT GACGGTGCAG 
GCAAACCGAT ATAGTGAGGC CCACCCACAG GAACCAGCTG ATGGCCAGGA GGTCCTCCAA 
GCCATGAGGA GCTATGTTCA GTTCTTCTTT GGCTGTCGTG ACTGTGCGGA CCATTTTGAG 
CAGATGGCTG CAGCGTCCAT GCACCAAGTG AGAAGTCCCA GTAATGCGAT TCTTTGGCTC 
TGGACTAGCC ACAACAGGGT TAACGCTCGC CTCTCAGGTG CTCTGAGTGA GGACCCCCAC 
TTCCCCAAGG TGCAGTGGCC TCCCCGTGAG CTGTGTTCTG CCTGCCATAA TGAACTCAAC 
GGACAGGTGC CTTTGTGGGA CCTTGGTGCC ACCCTCAACT TTCTCAAGGC TCACTTCTCC 
CCAGCAAACA TCGTCATAGA CTCTTCTGCA TCTAGACACA CAGGCCGGAG AGGGAGTCCA 
GAAGCTACCC CCGAGCTGCT CTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075757.1
CDS	101..1807
Translation	MRRCGRLSGPPSLLLLLLLLSPLLFSGPGAYAARLSVLYSSSDPLTLLDADSVRPTVLGSSSAWAVEFFASWCGHCIAFAPTWKELANDVKDWRPALNLAVLDCAEETNSAVCREFNIAGFPTVRFFQAFTKNGSGATLPGAGANVQTLRMRLIDALESHRDTWPPACPPLEPAKLNDIDGFFTRNKADYLALVFEREDSYLGREVTLDLSQYHAVAVRRVLNTESDLVNKFGVTDFPSCYLLLRNGSVSRVPVLVESRSFYTSYLRGLPGLTRDAPPTTATPVTADKIAPTVWKFADRSKIYMADLESALHYILRVEVGKFSVLEGQRLVALKKFVAVLAKYFPGQPLVQNFLHSINDWLQKQQKKRIPYSFFKAALDSRKEDAVLTEKVNWVGCQGSEPHFRGFPCSLWVLFHFLTVQANRYSEAHPQEPADGQEVLQAMRSYVQFFFGCRDCADHFEQMAAASMHQVRSPSNAILWLWTSHNRVNARLSGALSEDPHFPKVQWPPRELCSACHNELNGQVPLWDLGATLNFLKAHFSPANIVIDSSASRHTGRRGSPEATPELLL

Target ORF information:

RefSeq Version	NM_023268.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus quiescin Q6 sulfhydryl oxidase 1 (Qsox1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023268.2

ORF Insert Sequence:

ATGAGGAGGT GCGGCCGCCT CTCGGGGCCG CCATCGCTGC TGCTACTACT GCTGCTGCTC 
TCGCCTCTGC TCTTCTCGGG GCCCGGCGCT TACGCGGCCC GGCTCTCAGT GCTCTACTCG 
TCCTCTGACC CGCTGACGCT GCTGGATGCT GATTCGGTGC GTCCCACTGT GCTCGGCTCC 
AGCAGCGCCT GGGCGGTGGA GTTCTTCGCC TCCTGGTGTG GCCACTGCAT CGCCTTCGCC 
CCGACGTGGA AGGAGCTTGC TAACGACGTG AAAGACTGGA GGCCAGCACT CAATCTTGCT 
GTCCTGGACT GTGCTGAGGA GACCAACAGT GCTGTCTGCA GAGAGTTCAA CATCGCTGGC 
TTCCCGACTG TGAGGTTTTT TCAGGCCTTT ACCAAGAACG GTTCTGGAGC GACACTGCCA 
GGTGCTGGCG CTAATGTGCA GACTCTGCGT ATGAGGCTCA TCGATGCTCT GGAGTCCCAC 
CGTGACACAT GGCCCCCAGC CTGTCCACCT CTGGAACCTG CCAAGCTGAA TGATATCGAC 
GGATTCTTTA CAAGAAATAA AGCAGATTAC CTGGCCCTGG TCTTTGAAAG GGAAGACTCC 
TACCTGGGTA GAGAGGTAAC TCTGGACCTG TCCCAGTACC ATGCTGTGGC AGTGCGCAGG 
GTCTTGAATA CAGAGAGTGA CCTGGTGAAC AAGTTTGGCG TCACTGACTT CCCATCTTGT 
TACCTGCTGC TTCGGAATGG CTCTGTCTCC CGAGTGCCTG TGCTGGTGGA GTCCAGGTCT 
TTCTATACAT CCTATCTTCG GGGGCTACCT GGACTGACCA GGGATGCTCC CCCAACCACA 
GCCACCCCAG TCACTGCTGA TAAGATAGCA CCCACAGTGT GGAAGTTTGC AGACCGCTCC 
AAGATCTACA TGGCCGACCT GGAGTCCGCA CTCCACTACA TCTTGCGTGT AGAAGTGGGG 
AAGTTCTCAG TGCTGGAGGG ACAGCGCCTG GTGGCCCTGA AAAAGTTTGT GGCAGTATTG 
GCCAAGTACT TCCCTGGGCA GCCTTTGGTC CAGAACTTCT TGCATTCCAT AAACGACTGG 
CTTCAGAAGC AGCAGAAGAA GAGGATCCCC TACAGTTTCT TCAAAGCTGC TCTGGACAGC 
AGGAAGGAGG ATGCTGTCCT TACTGAGAAG GTGAACTGGG TCGGCTGCCA GGGCAGTGAG 
CCACACTTCC GGGGGTTTCC CTGCTCACTG TGGGTCCTCT TCCACTTCCT GACGGTGCAG 
GCAAACCGAT ATAGTGAGGC CCACCCACAG GAACCAGCTG ATGGCCAGGA GGTCCTCCAA 
GCCATGAGGA GCTATGTTCA GTTCTTCTTT GGCTGTCGTG ACTGTGCGGA CCATTTTGAG 
CAGATGGCTG CAGCGTCCAT GCACCAAGTG AGAAGTCCCA GTAATGCGAT TCTTTGGCTC 
TGGACTAGCC ACAACAGGGT TAACGCTCGC CTCTCAGGTG CTCTGAGTGA GGACCCCCAC 
TTCCCCAAGG TGCAGTGGCC TCCCCGTGAG CTGTGTTCTG CCTGCCATAA TGAACTCAAC 
GGACAGGTGC CTTTGTGGGA CCTTGGTGCC ACCCTCAACT TTCTCAAGGC TCACTTCTCC 
CCAGCAAACA TCGTCATAGA CTCTTCTGCA TCTAGACACA CAGGCCGGAG AGGGAGTCCA 
GAAGCTACCC CCGAGCTGCT CTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Qsox1 ( NM_001024945.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001020116.1 Mus musculus quiescin Q6 sulfhydryl oxidase 1 (Qsox1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu12020
Clone ID Related Accession (Same CDS sequence)	NM_001024945.1
Accession Version	NM_001024945.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2247bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	sulfhydryl oxidase 1 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY334148.1, AK083938.1 and CK625426.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC076590.1, AK083938.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGAGGAGGT GCGGCCGCCT CTCGGGGCCG CCATCGCTGC TGCTACTACT GCTGCTGCTC 
TCGCCTCTGC TCTTCTCGGG GCCCGGCGCT TACGCGGCCC GGCTCTCAGT GCTCTACTCG 
TCCTCTGACC CGCTGACGCT GCTGGATGCT GATTCGGTGC GTCCCACTGT GCTCGGCTCC 
AGCAGCGCCT GGGCGGTGGA GTTCTTCGCC TCCTGGTGTG GCCACTGCAT CGCCTTCGCC 
CCGACGTGGA AGGAGCTTGC TAACGACGTG AAAGACTGGA GGCCAGCACT CAATCTTGCT 
GTCCTGGACT GTGCTGAGGA GACCAACAGT GCTGTCTGCA GAGAGTTCAA CATCGCTGGC 
TTCCCGACTG TGAGGTTTTT TCAGGCCTTT ACCAAGAACG GTTCTGGAGC GACACTGCCA 
GGTGCTGGCG CTAATGTGCA GACTCTGCGT ATGAGGCTCA TCGATGCTCT GGAGTCCCAC 
CGTGACACAT GGCCCCCAGC CTGTCCACCT CTGGAACCTG CCAAGCTGAA TGATATCGAC 
GGATTCTTTA CAAGAAATAA AGCAGATTAC CTGGCCCTGG TCTTTGAAAG GGAAGACTCC 
TACCTGGGTA GAGAGGTAAC TCTGGACCTG TCCCAGTACC ATGCTGTGGC AGTGCGCAGG 
GTCTTGAATA CAGAGAGTGA CCTGGTGAAC AAGTTTGGCG TCACTGACTT CCCATCTTGT 
TACCTGCTGC TTCGGAATGG CTCTGTCTCC CGAGTGCCTG TGCTGGTGGA GTCCAGGTCT 
TTCTATACAT CCTATCTTCG GGGGCTACCT GGACTGACCA GGGATGCTCC CCCAACCACA 
GCCACCCCAG TCACTGCTGA TAAGATAGCA CCCACAGTGT GGAAGTTTGC AGACCGCTCC 
AAGATCTACA TGGCCGACCT GGAGTCCGCA CTCCACTACA TCTTGCGTGT AGAAGTGGGG 
AAGTTCTCAG TGCTGGAGGG ACAGCGCCTG GTGGCCCTGA AAAAGTTTGT GGCAGTATTG 
GCCAAGTACT TCCCTGGGCA GCCTTTGGTC CAGAACTTCT TGCATTCCAT AAACGACTGG 
CTTCAGAAGC AGCAGAAGAA GAGGATCCCC TACAGTTTCT TCAAAGCTGC TCTGGACAGC 
AGGAAGGAGG ATGCTGTCCT TACTGAGAAG GTGAACTGGG TCGGCTGCCA GGGCAGTGAG 
CCACACTTCC GGGGGTTTCC CTGCTCACTG TGGGTCCTCT TCCACTTCCT GACGGTGCAG 
GCAAACCGAT ATAGTGAGGC CCACCCACAG GAACCAGCTG ATGGCCAGGA GGTCCTCCAA 
GCCATGAGGA GCTATGTTCA GTTCTTCTTT GGCTGTCGTG ACTGTGCGGA CCATTTTGAG 
CAGATGGCTG CAGCGTCCAT GCACCAAGTG AGAAGTCCCA GTAATGCGAT TCTTTGGCTC 
TGGACTAGCC ACAACAGGGT TAACGCTCGC CTCTCAGGTG CTCTGAGTGA GGACCCCCAC 
TTCCCCAAGG TGCAGTGGCC TCCCCGTGAG CTGTGTTCTG CCTGCCATAA TGAACTCAAC 
GGACAGGTGC CTTTGTGGGA CCTTGGTGCC ACCCTCAACT TTCTCAAGGC TCACTTCTCC 
CCAGCAAACA TCGTCATAGA CTCTTCTGCA TCTAGACACA CAGGCCGGAG AGGGAGTCCA 
GAAGCTACCC CCGAGCTGGT AATGGATACA TTAAAACTGG AGAGCAGAAA TTCAGTGTTG 
GGCCATGAGC AGGCTGCTTC TGCAGAGTCC CCTGGAGCCA CTGCCCTAGA TGTACCAGCT 
GAGAAGCCTG AAGCAAGTGG CCCCCAAGAA CTATACACAG GCCTCAGAAT GGGTGGAGCT 
TCACCAGGGC AGGGCCCTCC TGAGCGCATG GAAGACCACC AGAGGGATAT GCAGGAGAAT 
GCCCCCGGGC AGCAACACTT GAGCAAGAGA GACACTGAAG CCTTATTTCT GCCTGAGGTG 
AACCACCTCC AAGGCCCTTT AGAGCTCAGG CGAGGGGGCC GCAGCCCCAA GCAACTAGCC 
CCCATACTTG AAGAGGAACC AGAGGCCCTA GCTATACAGG GCCAAGGCCA GTGGCTGCAG 
GTTCTAGGAG GGGGCATTTC CCACCTGGAC ATTAGCCTCT GTGTGGGGCT CTACTCCGTG 
TCCTTCATGG GCTTACTGGC CATGTACACC TACTTTCGGG CCAGGCTGAG AACCCCAAAG 
GGCCATGCTA GTTACCCCAC AGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020116.1
CDS	101..2347
Translation	MRRCGRLSGPPSLLLLLLLLSPLLFSGPGAYAARLSVLYSSSDPLTLLDADSVRPTVLGSSSAWAVEFFASWCGHCIAFAPTWKELANDVKDWRPALNLAVLDCAEETNSAVCREFNIAGFPTVRFFQAFTKNGSGATLPGAGANVQTLRMRLIDALESHRDTWPPACPPLEPAKLNDIDGFFTRNKADYLALVFEREDSYLGREVTLDLSQYHAVAVRRVLNTESDLVNKFGVTDFPSCYLLLRNGSVSRVPVLVESRSFYTSYLRGLPGLTRDAPPTTATPVTADKIAPTVWKFADRSKIYMADLESALHYILRVEVGKFSVLEGQRLVALKKFVAVLAKYFPGQPLVQNFLHSINDWLQKQQKKRIPYSFFKAALDSRKEDAVLTEKVNWVGCQGSEPHFRGFPCSLWVLFHFLTVQANRYSEAHPQEPADGQEVLQAMRSYVQFFFGCRDCADHFEQMAAASMHQVRSPSNAILWLWTSHNRVNARLSGALSEDPHFPKVQWPPRELCSACHNELNGQVPLWDLGATLNFLKAHFSPANIVIDSSASRHTGRRGSPEATPELVMDTLKLESRNSVLGHEQAASAESPGATALDVPAEKPEASGPQELYTGLRMGGASPGQGPPERMEDHQRDMQENAPGQQHLSKRDTEALFLPEVNHLQGPLELRRGGRSPKQLAPILEEEPEALAIQGQGQWLQVLGGGISHLDISLCVGLYSVSFMGLLAMYTYFRARLRTPKGHASYPTA

Target ORF information:

RefSeq Version	NM_001024945.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus quiescin Q6 sulfhydryl oxidase 1 (Qsox1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024945.1

ORF Insert Sequence:

ATGAGGAGGT GCGGCCGCCT CTCGGGGCCG CCATCGCTGC TGCTACTACT GCTGCTGCTC 
TCGCCTCTGC TCTTCTCGGG GCCCGGCGCT TACGCGGCCC GGCTCTCAGT GCTCTACTCG 
TCCTCTGACC CGCTGACGCT GCTGGATGCT GATTCGGTGC GTCCCACTGT GCTCGGCTCC 
AGCAGCGCCT GGGCGGTGGA GTTCTTCGCC TCCTGGTGTG GCCACTGCAT CGCCTTCGCC 
CCGACGTGGA AGGAGCTTGC TAACGACGTG AAAGACTGGA GGCCAGCACT CAATCTTGCT 
GTCCTGGACT GTGCTGAGGA GACCAACAGT GCTGTCTGCA GAGAGTTCAA CATCGCTGGC 
TTCCCGACTG TGAGGTTTTT TCAGGCCTTT ACCAAGAACG GTTCTGGAGC GACACTGCCA 
GGTGCTGGCG CTAATGTGCA GACTCTGCGT ATGAGGCTCA TCGATGCTCT GGAGTCCCAC 
CGTGACACAT GGCCCCCAGC CTGTCCACCT CTGGAACCTG CCAAGCTGAA TGATATCGAC 
GGATTCTTTA CAAGAAATAA AGCAGATTAC CTGGCCCTGG TCTTTGAAAG GGAAGACTCC 
TACCTGGGTA GAGAGGTAAC TCTGGACCTG TCCCAGTACC ATGCTGTGGC AGTGCGCAGG 
GTCTTGAATA CAGAGAGTGA CCTGGTGAAC AAGTTTGGCG TCACTGACTT CCCATCTTGT 
TACCTGCTGC TTCGGAATGG CTCTGTCTCC CGAGTGCCTG TGCTGGTGGA GTCCAGGTCT 
TTCTATACAT CCTATCTTCG GGGGCTACCT GGACTGACCA GGGATGCTCC CCCAACCACA 
GCCACCCCAG TCACTGCTGA TAAGATAGCA CCCACAGTGT GGAAGTTTGC AGACCGCTCC 
AAGATCTACA TGGCCGACCT GGAGTCCGCA CTCCACTACA TCTTGCGTGT AGAAGTGGGG 
AAGTTCTCAG TGCTGGAGGG ACAGCGCCTG GTGGCCCTGA AAAAGTTTGT GGCAGTATTG 
GCCAAGTACT TCCCTGGGCA GCCTTTGGTC CAGAACTTCT TGCATTCCAT AAACGACTGG 
CTTCAGAAGC AGCAGAAGAA GAGGATCCCC TACAGTTTCT TCAAAGCTGC TCTGGACAGC 
AGGAAGGAGG ATGCTGTCCT TACTGAGAAG GTGAACTGGG TCGGCTGCCA GGGCAGTGAG 
CCACACTTCC GGGGGTTTCC CTGCTCACTG TGGGTCCTCT TCCACTTCCT GACGGTGCAG 
GCAAACCGAT ATAGTGAGGC CCACCCACAG GAACCAGCTG ATGGCCAGGA GGTCCTCCAA 
GCCATGAGGA GCTATGTTCA GTTCTTCTTT GGCTGTCGTG ACTGTGCGGA CCATTTTGAG 
CAGATGGCTG CAGCGTCCAT GCACCAAGTG AGAAGTCCCA GTAATGCGAT TCTTTGGCTC 
TGGACTAGCC ACAACAGGGT TAACGCTCGC CTCTCAGGTG CTCTGAGTGA GGACCCCCAC 
TTCCCCAAGG TGCAGTGGCC TCCCCGTGAG CTGTGTTCTG CCTGCCATAA TGAACTCAAC 
GGACAGGTGC CTTTGTGGGA CCTTGGTGCC ACCCTCAACT TTCTCAAGGC TCACTTCTCC 
CCAGCAAACA TCGTCATAGA CTCTTCTGCA TCTAGACACA CAGGCCGGAG AGGGAGTCCA 
GAAGCTACCC CCGAGCTGGT AATGGATACA TTAAAACTGG AGAGCAGAAA TTCAGTGTTG 
GGCCATGAGC AGGCTGCTTC TGCAGAGTCC CCTGGAGCCA CTGCCCTAGA TGTACCAGCT 
GAGAAGCCTG AAGCAAGTGG CCCCCAAGAA CTATACACAG GCCTCAGAAT GGGTGGAGCT 
TCACCAGGGC AGGGCCCTCC TGAGCGCATG GAAGACCACC AGAGGGATAT GCAGGAGAAT 
GCCCCCGGGC AGCAACACTT GAGCAAGAGA GACACTGAAG CCTTATTTCT GCCTGAGGTG 
AACCACCTCC AAGGCCCTTT AGAGCTCAGG CGAGGGGGCC GCAGCCCCAA GCAACTAGCC 
CCCATACTTG AAGAGGAACC AGAGGCCCTA GCTATACAGG GCCAAGGCCA GTGGCTGCAG 
GTTCTAGGAG GGGGCATTTC CCACCTGGAC ATTAGCCTCT GTGTGGGGCT CTACTCCGTG 
TCCTTCATGG GCTTACTGGC CATGTACACC TACTTTCGGG CCAGGCTGAG AACCCCAAAG 
GGCCATGCTA GTTACCCCAC AGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms.
Free radical biology & medicine99426-435(2016 10)
Zhang L,Cheng Q,Zhang L,Wang Y,Merrill GF,Ilani T,Fass D,Arn?r ESJ,Zhang J

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Nature521(7553)520-4(2015 May)
Li Y,Klena NT,Gabriel GC,Liu X,Kim AJ,Lemke K,Chen Y,Chatterjee B,Devine W,Damerla RR,Chang C,Yagi H,San Agustin JT,Thahir M,Anderton S,Lawhead C,Vescovi A,Pratt H,Morgan J,Haynes L,Smith CL,Eppig JT,Reinholdt L,Francis R,Leatherbury L,Ganapathiraju MK,Tobita K,Pazour GJ,Lo CW

QSOX1 inhibits autophagic flux in breast cancer cells.
PloS one9(1)e86641(2014)
Poillet L,Pernodet N,Boyer-Guittaut M,Adami P,Borg C,Jouvenot M,Delage-Mourroux R,Despouy G

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Qsox1 cDNA ORF clone, Mus musculus(house mouse)

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ORF Insert Sequence:

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