Maml1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Maml1
Entrez Gene ID	103806
Full Name	mastermind like transcriptional coactivator 1
Synonyms	AI644666,AW743257,D930008C07Rik,Mam-1,Mam1,mKIAA0200
General protein information	Preferred Names mastermind like transcriptional coactivator 1 Names mastermind-like protein 1 maml1 mastermind like 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B1.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006531918.3	XP_006531981.1	mastermind-like protein 1 isoform X1
XM_006531918.4	XP_006531981.1	mastermind-like protein 1 isoform X1
NM_175334.3	NP_780543.2	mastermind-like protein 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Maml1	NP_001100467.1
Homo sapiens (human)	MAML1	NP_055572.1
	MAML1	XP_001105097.2
Bos taurus (cattle)	MAML1	XP_005208449.1
Gallus gallus (chicken)	MAML1	XP_414607.4
Mus musculus (house mouse)	Maml1	NP_780543.2
Danio rerio (zebrafish)	LOC567335	XP_005157273.1
Pan troglodytes (chimpanzee)	MAML1	XP_527150.3
Canis lupus familiaris (dog)	MAML1	XP_005626406.1
Xenopus tropicalis (tropical clawed frog)	maml1	XP_002941844.2

Gene Ontology
Bibliography

Related articles in PubMed

Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway.
Quaranta R, Pelullo M, Zema S, Nardozza F, Checquolo S, Lauer DM, Bufalieri F, Palermo R, Felli MP, Vacca A, Talora C, Di Marcotullio L, Screpanti I, Bellavia D
Cell death & disease8(7)e2942(2017 Jul)

Olfactory Sensory Neurons Control Dendritic Complexity of Mitral Cells via Notch Signaling.
Muroyama Y, Baba A, Kitagawa M, Saito T
PLoS genetics12(12)e1006514(2016 Dec)

Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway.
Grisanti L, Revenkova E, Gordon RE, Iomini C
Development (Cambridge, England)143(12)2160-71(2016 06)

CbGRiTS: cerebellar gene regulation in time and space.
Ha T, Swanson D, Larouche M, Glenn R, Weeden D, Zhang P, Hamre K, Langston M, Phillips C, Song M, Ouyang Z, Chesler E, Duvvurru S, Yordanova R, Cui Y, Campbell K, Ricker G, Phillips C, Homayouni R, Goldowitz D
Developmental biology397(1)18-30(2015 Jan)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Similar phenotypes were observed by conditionally misexpressing a dominant negative form of MAML1 in Mitral cells ( MCs)after their migration. Furthermore, the intracellular domain of Notch1 (NICD1) was localized to nuclei of MCs. These findings suggest that Notch signaling at embryonic stages is involved in the dendritic complexity of MCs
Title: Olfactory Sensory Neurons Control Dendritic Complexity of Mitral Cells via Notch Signaling.

Maml-mediated Notch signaling plays a pivotal role in the initiation and maintenance of goblet cell differentiation for normal ocular surface morphogenesis.
Title: Mastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity.

These observations suggest that chondrocyte maturation was impaired in MAML1(-/-) mice. MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development.
Title: MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development.

This study demonstrated that targeting Maml1-induced tumor cell senescence and differentiation may alter the tumor microenvironment and cytokine and chemokine profiles and may also promote innate and adaptive immune cell infiltration and function.
Title: A knockdown of Maml1 that results in melanoma cell senescence promotes an innate and adaptive immune response.

Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo.
Title: Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo.

The following Maml1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Maml1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu45361	XM_006531918.4 Latest version!	Mus musculus mastermind like transcriptional coactivator 1 (Maml1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OMu18750	NM_175334.3 Latest version!	Mus musculus mastermind like transcriptional coactivator 1 (Maml1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
View Old Accession Versions >>
OMu45361	XM_006531918.3	Mus musculus mastermind like 1 (Drosophila) (Maml1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Maml1 ( XM_006531918.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006531981.1 Mus musculus mastermind like transcriptional coactivator 1 (Maml1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu45361
Clone ID Related Accession (Same CDS sequence)	XM_006531918.3 , XM_006531918.4
Accession Version	XM_006531918.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3183bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	mastermind-like protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006531918.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTAC CCACCTGCCC CATGGCGGAG TTCGCGCTGC CGCGGCACAG CGCGGTCATG 
GAGCGCCTCC GCCGGCGCAT CGAACTGTGC CGGCGCCACC ACAGCACCTG TGAGGCCCGC 
TACGAGGCTG TGTCTCCCGA GCGCCTGGAG CTCGAGCGCC AGCACACCTT TGCCCTGCAC 
CAGCGCTGCA TCCAGGCCAA GGCCAAGCGC GCCGGCAAGC ACCGGCAGCC GCCGGCCGCC 
GCCACGGCCC CGGTTGCCGC TCCGGCCCCC GCCTCGGCCC CGGCGGCCGC GCGCCTGGAC 
GCAGCGGACG GCCCGGAGCA CGGCCGCCCG GTCGCGGGCT ATTGCTTTCC TTCCTTCCCA 
CACTATCCCC GCTGCGAGAC CACACGGCAG AACACACCGG TTCTGACCCA GCTGCTCGAG 
TCTTCTCATC CTCACTTTCC CGCCTGTAAA TCGAGGCATC TTCATGATAC AGTGAAGAGG 
AGTCTTGACA GTGCTGCCTC CCCTCAGAAT GGCGATCAAC CAAATGGCTA CGGAGACTTG 
TTTCCTGGGC ATAAGAAGAC ACGCCGGGAG GCCCCTCTGG GGGTCAGTGT GTCTGCCAAT 
GGGCTTCCTC CTGCCTCGCC CCTGGGCCAG CCCGACAAGC CTTCAGGGGG AGACACCCTG 
CAGACCGCTG GGAAGCACTC TCTGGGGCTC GATCCCATCA ACAAGAAGTG TCTGGCAGAC 
TCAGGCATCC ACCTGAATGG AGGCAGCAAC TCCAGTGAGC CCTTTCCTCT AAGCCTGAGT 
AAAGAACTCA AGCAGGAGCC AGTGGACGAC CTGCCGTGCA TGATCGCGGG CGCTGGAGGC 
TCCGTAGCTC AGAGCAACCT CATGCCGGAC CTCAACCTTA ATGAGCAGGA GTGGAAGGAG 
CTCATCGAGG AGCTCAACAG GTCAGTGCCC GACGAAGACA TGAAGGACCT GTTTACGGAG 
GACTTTGAGG AGAAGAAGGA TCCAGAGCCT CCTGGCTCTG CCACACAAAC CCCCCTGGCC 
CAGGACATTA ATATTAAGAC TGAGTTCTCT CCAGCAGCTT TTGAGCAGGA GCAGTTAGGT 
TCTCCACAAG TAAGGGCTGG GTCTGCAGGC CAGACCTTCC TAGGAGCCTC ATCTGCCCCT 
GTGGGCACAG ATTCTCCAAG CCTTGGGAGC TCTCAGACTC TGTTTCACAC AACTAGTCAA 
CCTGGGGTGG ATAATTCCAG TCCAAACCTG ATGCCGGCAT CAGCCCAGGC TCAAAGTGCA 
CAAAGAGCCC TCACGAGTGT GGTATTACCT AGCCAGGGCC CAGGCGGGGC CTCGGAGCTG 
TCCTCTGCTC ACCAGCTCCA GCAGATAGCT GCCAAGCAGA AGCGCGAGCA GATGTTGCAG 
AATCCCCAGC AAGCTGCCCC AGCACCCGGC CCAGGCCAGC TGGCCACGTG GCAGCAGGCA 
GGGCCCTCCC ACAGTCCCTT AGATGTTCCT TATCCCATGG AGAAGCCTGC CAGCCCTTCT 
GGCTACAAGC AAGACTTTAC CAACTCAAAA CTGCTCATGA TGCCCGGTGT GAACAAGAGT 
TCTCCTCGGC CAGGAGGCCC CTACCTCCAA CCTAGCCACT CCAACCTGCT GAGTCACCAG 
TCACCAAGTA ACTTGAATCA GAACCCCGTG AATAACCAAG GGTCTGTGCT AGACTATGGC 
AATACAAAGC CCCTTTCTCA TTACAAAGCA GACTGTGGCC AAGGTGGTCC TGGGTCTGGC 
CAGAACAAAC CAGCTTTGAT GGCATATCTT CCCCAGCAGC TGCCCCATCT GAGTAACGAG 
CAGAACTCCT TGTTTCTGAT GAAACCAAAG TCAGGAAACA TGCCCTTCCG GTCATTGGTT 
CCACCTGGCC AGGAGCAGAA CCCTTCCAGT GTCCCTGTAG CTGCCCCAGC TGCCAGTGTG 
GGAACCCAGC CTACTGTGTC TGTGGCCAGC ACTCACAACA GCTCGCCATA CCTCAGCAGC 
CAGCAGCAGG CAGCTGTGAT GAAGCAGCAC CAGCTGCTCC TGGACCAGCA GAAGCAGAGG 
GAGCAGCAGC AGCAGCAGCT GCAGCAGCAG CAGTTCCTGC AGAGGCAGCA CCTCCTGGCT 
GAGCAGGAGA AACAACAGTT TCAGCGTCAT CTGACCCGCC CACCCCCCCA GTACCAAGAC 
CCAACACAAA GCACCTTCCC ACAACAGGTT GGACAGTTCA CAGGACCTTC TGCTGCTGTG 
CCTGGGATGA ACAACTTGGG TCCGTCCAAC TCCAGCTGTC CTCGAGTGTT CCCTCAGCCT 
GGGACTCTGA TGTCCATGGG CCCTGGACAT GCCCCTGTCT CCTCTCTCCC CTCCAGCTCA 
GGCCAGCAGG ACCGTGGAGT GGCCCAGTTT ACTGGGTCCC AGAGTTTGCC TCAGAACAGC 
CTTTATGGCA TGGCATCTGG CCTAGCCCAG ATAGTTGCCC AGCCCCCACC ACAGGCTACC 
AGCACACATG CCCACATTCC ACGGCAGACC AACGTGGGCC AGAACGCCTC CACCTCGGCT 
GCATATGGAC AGAACTCTCT GGGGAGTGCC AGTCTTTCCC AGCAGCACAG TAAGGGAACC 
CTGCCTCCTG GTTTAACAAA GCCACAAGTC CCAAGGGTGT CAGCAGCCAT GGGAAGCCAG 
AATGCCTCGT GGCAGCATCA GGGAATGCCA AACCTGAGCA GCCAGACGTC TGGGAACAGC 
AGTGTGAACC CCTTCACTGC AGCTCCCAGT TTCCACATAC AGCAAGCCCA CCTGAAACTA 
GCTGGCCAGC AGTTCTCCCA AGCCATGCCC AGCAGGCCCA TGGCGCCTCT GAGTTCAGCA 
GGTGCAGCAG GGCCCATGCT GCCCCCAGTG AGTGCACAGC AGAGGAACAG TGCCCCTGCA 
TCTGCACCTC CCCAAGCAGC CCCGCAGCAG GGCTTGCCTG GCTTAAGTCC TTCGGGGCCC 
GAGCTGGGGG CCTTCGGCCA GAGCCCCACC TCCCAGATGA GCGGCCGGCC AGGGCTACAC 
TGTGCGCAGG CTTACCCTGT GAGGACCATG GGCCAAGAGC TGCCCTTTGC CTACAGCGGG 
CAGCCAGGTA GCAGTGGTCT GTCCAGTGTG GCTGGACACA CTGACCTGAT CGACTCGCTG 
CTGAAGAACA GGACTTCTGA GGAGTGGATC AATGAATTGG ATGATCTTTT AGGGTCACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006531981.1
CDS	1071..4253
Translation	MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRPVAGYCFPSFPHYPRCETTRQNTPVLTQLLESSHPHFPACKSRHLHDTVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGASSAPVGTDSPSLGSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNQNPVNNQGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVPVAAPAASVGTQPTVSVASTHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQQQLQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLTKPQVPRVSAAMGSQNASWQHQGMPNLSSQTSGNSSVNPFTAAPSFHIQQAHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPVSAQQRNSAPASAPPQAAPQQGLPGLSPSGPELGAFGQSPTSQMSGRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ

Target ORF information:

RefSeq Version	XM_006531918.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus mastermind like transcriptional coactivator 1 (Maml1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006531918.4

ORF Insert Sequence:

ATGGTGCTAC CCACCTGCCC CATGGCGGAG TTCGCGCTGC CGCGGCACAG CGCGGTCATG 
GAGCGCCTCC GCCGGCGCAT CGAACTGTGC CGGCGCCACC ACAGCACCTG TGAGGCCCGC 
TACGAGGCTG TGTCTCCCGA GCGCCTGGAG CTCGAGCGCC AGCACACCTT TGCCCTGCAC 
CAGCGCTGCA TCCAGGCCAA GGCCAAGCGC GCCGGCAAGC ACCGGCAGCC GCCGGCCGCC 
GCCACGGCCC CGGTTGCCGC TCCGGCCCCC GCCTCGGCCC CGGCGGCCGC GCGCCTGGAC 
GCAGCGGACG GCCCGGAGCA CGGCCGCCCG GTCGCGGGCT ATTGCTTTCC TTCCTTCCCA 
CACTATCCCC GCTGCGAGAC CACACGGCAG AACACACCGG TTCTGACCCA GCTGCTCGAG 
TCTTCTCATC CTCACTTTCC CGCCTGTAAA TCGAGGCATC TTCATGATAC AGTGAAGAGG 
AGTCTTGACA GTGCTGCCTC CCCTCAGAAT GGCGATCAAC CAAATGGCTA CGGAGACTTG 
TTTCCTGGGC ATAAGAAGAC ACGCCGGGAG GCCCCTCTGG GGGTCAGTGT GTCTGCCAAT 
GGGCTTCCTC CTGCCTCGCC CCTGGGCCAG CCCGACAAGC CTTCAGGGGG AGACACCCTG 
CAGACCGCTG GGAAGCACTC TCTGGGGCTC GATCCCATCA ACAAGAAGTG TCTGGCAGAC 
TCAGGCATCC ACCTGAATGG AGGCAGCAAC TCCAGTGAGC CCTTTCCTCT AAGCCTGAGT 
AAAGAACTCA AGCAGGAGCC AGTGGACGAC CTGCCGTGCA TGATCGCGGG CGCTGGAGGC 
TCCGTAGCTC AGAGCAACCT CATGCCGGAC CTCAACCTTA ATGAGCAGGA GTGGAAGGAG 
CTCATCGAGG AGCTCAACAG GTCAGTGCCC GACGAAGACA TGAAGGACCT GTTTACGGAG 
GACTTTGAGG AGAAGAAGGA TCCAGAGCCT CCTGGCTCTG CCACACAAAC CCCCCTGGCC 
CAGGACATTA ATATTAAGAC TGAGTTCTCT CCAGCAGCTT TTGAGCAGGA GCAGTTAGGT 
TCTCCACAAG TAAGGGCTGG GTCTGCAGGC CAGACCTTCC TAGGAGCCTC ATCTGCCCCT 
GTGGGCACAG ATTCTCCAAG CCTTGGGAGC TCTCAGACTC TGTTTCACAC AACTAGTCAA 
CCTGGGGTGG ATAATTCCAG TCCAAACCTG ATGCCGGCAT CAGCCCAGGC TCAAAGTGCA 
CAAAGAGCCC TCACGAGTGT GGTATTACCT AGCCAGGGCC CAGGCGGGGC CTCGGAGCTG 
TCCTCTGCTC ACCAGCTCCA GCAGATAGCT GCCAAGCAGA AGCGCGAGCA GATGTTGCAG 
AATCCCCAGC AAGCTGCCCC AGCACCCGGC CCAGGCCAGC TGGCCACGTG GCAGCAGGCA 
GGGCCCTCCC ACAGTCCCTT AGATGTTCCT TATCCCATGG AGAAGCCTGC CAGCCCTTCT 
GGCTACAAGC AAGACTTTAC CAACTCAAAA CTGCTCATGA TGCCCGGTGT GAACAAGAGT 
TCTCCTCGGC CAGGAGGCCC CTACCTCCAA CCTAGCCACT CCAACCTGCT GAGTCACCAG 
TCACCAAGTA ACTTGAATCA GAACCCCGTG AATAACCAAG GGTCTGTGCT AGACTATGGC 
AATACAAAGC CCCTTTCTCA TTACAAAGCA GACTGTGGCC AAGGTGGTCC TGGGTCTGGC 
CAGAACAAAC CAGCTTTGAT GGCATATCTT CCCCAGCAGC TGCCCCATCT GAGTAACGAG 
CAGAACTCCT TGTTTCTGAT GAAACCAAAG TCAGGAAACA TGCCCTTCCG GTCATTGGTT 
CCACCTGGCC AGGAGCAGAA CCCTTCCAGT GTCCCTGTAG CTGCCCCAGC TGCCAGTGTG 
GGAACCCAGC CTACTGTGTC TGTGGCCAGC ACTCACAACA GCTCGCCATA CCTCAGCAGC 
CAGCAGCAGG CAGCTGTGAT GAAGCAGCAC CAGCTGCTCC TGGACCAGCA GAAGCAGAGG 
GAGCAGCAGC AGCAGCAGCT GCAGCAGCAG CAGTTCCTGC AGAGGCAGCA CCTCCTGGCT 
GAGCAGGAGA AACAACAGTT TCAGCGTCAT CTGACCCGCC CACCCCCCCA GTACCAAGAC 
CCAACACAAA GCACCTTCCC ACAACAGGTT GGACAGTTCA CAGGACCTTC TGCTGCTGTG 
CCTGGGATGA ACAACTTGGG TCCGTCCAAC TCCAGCTGTC CTCGAGTGTT CCCTCAGCCT 
GGGACTCTGA TGTCCATGGG CCCTGGACAT GCCCCTGTCT CCTCTCTCCC CTCCAGCTCA 
GGCCAGCAGG ACCGTGGAGT GGCCCAGTTT ACTGGGTCCC AGAGTTTGCC TCAGAACAGC 
CTTTATGGCA TGGCATCTGG CCTAGCCCAG ATAGTTGCCC AGCCCCCACC ACAGGCTACC 
AGCACACATG CCCACATTCC ACGGCAGACC AACGTGGGCC AGAACGCCTC CACCTCGGCT 
GCATATGGAC AGAACTCTCT GGGGAGTGCC AGTCTTTCCC AGCAGCACAG TAAGGGAACC 
CTGCCTCCTG GTTTAACAAA GCCACAAGTC CCAAGGGTGT CAGCAGCCAT GGGAAGCCAG 
AATGCCTCGT GGCAGCATCA GGGAATGCCA AACCTGAGCA GCCAGACGTC TGGGAACAGC 
AGTGTGAACC CCTTCACTGC AGCTCCCAGT TTCCACATAC AGCAAGCCCA CCTGAAACTA 
GCTGGCCAGC AGTTCTCCCA AGCCATGCCC AGCAGGCCCA TGGCGCCTCT GAGTTCAGCA 
GGTGCAGCAG GGCCCATGCT GCCCCCAGTG AGTGCACAGC AGAGGAACAG TGCCCCTGCA 
TCTGCACCTC CCCAAGCAGC CCCGCAGCAG GGCTTGCCTG GCTTAAGTCC TTCGGGGCCC 
GAGCTGGGGG CCTTCGGCCA GAGCCCCACC TCCCAGATGA GCGGCCGGCC AGGGCTACAC 
TGTGCGCAGG CTTACCCTGT GAGGACCATG GGCCAAGAGC TGCCCTTTGC CTACAGCGGG 
CAGCCAGGTA GCAGTGGTCT GTCCAGTGTG GCTGGACACA CTGACCTGAT CGACTCGCTG 
CTGAAGAACA GGACTTCTGA GGAGTGGATC AATGAATTGG ATGATCTTTT AGGGTCACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Maml1 ( NM_175334.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780543.2 Mus musculus mastermind like transcriptional coactivator 1 (Maml1), mRNA.

Price & Availability↑

CloneID	OMu18750
Clone ID Related Accession (Same CDS sequence)	NM_175334.3
Accession Version	NM_175334.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3063bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Mus musculus(house mouse)
Product	mastermind-like protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI509152.1, AK129088.1, BC058658.1 and BC094599.1. On Oct 3, 2007 this sequence version replaced NM_175334.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK129088.1, AY442299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCTAC CCACCTGCCC CATGGCGGAG TTCGCGCTGC CGCGGCACAG CGCGGTCATG 
GAGCGCCTCC GCCGGCGCAT CGAACTGTGC CGGCGCCACC ACAGCACCTG TGAGGCCCGC 
TACGAGGCTG TGTCTCCCGA GCGCCTGGAG CTCGAGCGCC AGCACACCTT TGCCCTGCAC 
CAGCGCTGCA TCCAGGCCAA GGCCAAGCGC GCCGGCAAGC ACCGGCAGCC GCCGGCCGCC 
GCCACGGCCC CGGTTGCCGC TCCGGCCCCC GCCTCGGCCC CGGCGGCCGC GCGCCTGGAC 
GCAGCGGACG GCCCGGAGCA CGGCCGCCCG GTCGCGCATC TTCATGATAC AGTGAAGAGG 
AGTCTTGACA GTGCTGCCTC CCCTCAGAAT GGCGATCAAC CAAATGGCTA CGGAGACTTG 
TTTCCTGGGC ATAAGAAGAC ACGCCGGGAG GCCCCTCTGG GGGTCAGTGT GTCTGCCAAT 
GGGCTTCCTC CTGCCTCGCC CCTGGGCCAG CCCGACAAGC CTTCAGGGGG AGACACCCTG 
CAGACCGCTG GGAAGCACTC TCTGGGGCTC GATCCCATCA ACAAGAAGTG TCTGGCAGAC 
TCAGGCATCC ACCTGAATGG AGGCAGCAAC TCCAGTGAGC CCTTTCCTCT AAGCCTGAGT 
AAAGAACTCA AGCAGGAGCC AGTGGACGAC CTGCCGTGCA TGATCGCGGG CGCTGGAGGC 
TCCGTAGCTC AGAGCAACCT CATGCCGGAC CTCAACCTTA ATGAGCAGGA GTGGAAGGAG 
CTCATCGAGG AGCTCAACAG GTCAGTGCCC GACGAAGACA TGAAGGACCT GTTTACGGAG 
GACTTTGAGG AGAAGAAGGA TCCAGAGCCT CCTGGCTCTG CCACACAAAC CCCCCTGGCC 
CAGGACATTA ATATTAAGAC TGAGTTCTCT CCAGCAGCTT TTGAGCAGGA GCAGTTAGGT 
TCTCCACAAG TAAGGGCTGG GTCTGCAGGC CAGACCTTCC TAGGAGCCTC ATCTGCCCCT 
GTGGGCACAG ATTCTCCAAG CCTTGGGAGC TCTCAGACTC TGTTTCACAC AACTAGTCAA 
CCTGGGGTGG ATAATTCCAG TCCAAACCTG ATGCCGGCAT CAGCCCAGGC TCAAAGTGCA 
CAAAGAGCCC TCACGAGTGT GGTATTACCT AGCCAGGGCC CAGGCGGGGC CTCGGAGCTG 
TCCTCTGCTC ACCAGCTCCA GCAGATAGCT GCCAAGCAGA AGCGCGAGCA GATGTTGCAG 
AATCCCCAGC AAGCTGCCCC AGCACCCGGC CCAGGCCAGC TGGCCACGTG GCAGCAGGCA 
GGGCCCTCCC ACAGTCCCTT AGATGTTCCT TATCCCATGG AGAAGCCTGC CAGCCCTTCT 
GGCTACAAGC AAGACTTTAC CAACTCAAAA CTGCTCATGA TGCCCGGTGT GAACAAGAGT 
TCTCCTCGGC CAGGAGGCCC CTACCTCCAA CCTAGCCACT CCAACCTGCT GAGTCACCAG 
TCACCAAGTA ACTTGAATCA GAACCCCGTG AATAACCAAG GGTCTGTGCT AGACTATGGC 
AATACAAAGC CCCTTTCTCA TTACAAAGCA GACTGTGGCC AAGGTGGTCC TGGGTCTGGC 
CAGAACAAAC CAGCTTTGAT GGCATATCTT CCCCAGCAGC TGCCCCATCT GAGTAACGAG 
CAGAACTCCT TGTTTCTGAT GAAACCAAAG TCAGGAAACA TGCCCTTCCG GTCATTGGTT 
CCACCTGGCC AGGAGCAGAA CCCTTCCAGT GTCCCTGTAG CTGCCCCAGC TGCCAGTGTG 
GGAACCCAGC CTACTGTGTC TGTGGCCAGC ACTCACAACA GCTCGCCATA CCTCAGCAGC 
CAGCAGCAGG CAGCTGTGAT GAAGCAGCAC CAGCTGCTCC TGGACCAGCA GAAGCAGAGG 
GAGCAGCAGC AGCAGCAGCT GCAGCAGCAG CAGTTCCTGC AGAGGCAGCA CCTCCTGGCT 
GAGCAGGAGA AACAACAGTT TCAGCGTCAT CTGACCCGCC CACCCCCCCA GTACCAAGAC 
CCAACACAAA GCACCTTCCC ACAACAGGTT GGACAGTTCA CAGGACCTTC TGCTGCTGTG 
CCTGGGATGA ACAACTTGGG TCCGTCCAAC TCCAGCTGTC CTCGAGTGTT CCCTCAGCCT 
GGGACTCTGA TGTCCATGGG CCCTGGACAT GCCCCTGTCT CCTCTCTCCC CTCCAGCTCA 
GGCCAGCAGG ACCGTGGAGT GGCCCAGTTT ACTGGGTCCC AGAGTTTGCC TCAGAACAGC 
CTTTATGGCA TGGCATCTGG CCTAGCCCAG ATAGTTGCCC AGCCCCCACC ACAGGCTACC 
AGCACACATG CCCACATTCC ACGGCAGACC AACGTGGGCC AGAACGCCTC CACCTCGGCT 
GCATATGGAC AGAACTCTCT GGGGAGTGCC AGTCTTTCCC AGCAGCACAG TAAGGGAACC 
CTGCCTCCTG GTTTAACAAA GCCACAAGTC CCAAGGGTGT CAGCAGCCAT GGGAAGCCAG 
AATGCCTCGT GGCAGCATCA GGGAATGCCA AACCTGAGCA GCCAGACGTC TGGGAACAGC 
AGTGTGAACC CCTTCACTGC AGCTCCCAGT TTCCACATAC AGCAAGCCCA CCTGAAACTA 
GCTGGCCAGC AGTTCTCCCA AGCCATGCCC AGCAGGCCCA TGGCGCCTCT GAGTTCAGCA 
GGTGCAGCAG GGCCCATGCT GCCCCCAGTG AGTGCACAGC AGAGGAACAG TGCCCCTGCA 
TCTGCACCTC CCCAAGCAGC CCCGCAGCAG GGCTTGCCTG GCTTAAGTCC TTCGGGGCCC 
GAGCTGGGGG CCTTCGGCCA GAGCCCCACC TCCCAGATGA GCGGCCGGCC AGGGCTACAC 
TGTGCGCAGG CTTACCCTGT GAGGACCATG GGCCAAGAGC TGCCCTTTGC CTACAGCGGG 
CAGCCAGGTA GCAGTGGTCT GTCCAGTGTG GCTGGACACA CTGACCTGAT CGACTCGCTG 
CTGAAGAACA GGACTTCTGA GGAGTGGATC AATGAATTGG ATGATCTTTT AGGGTCACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780543.2
CDS	276..3338
Translation	MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRPVAHLHDTVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGASSAPVGTDSPSLGSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNQNPVNNQGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVPVAAPAASVGTQPTVSVASTHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQQQLQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLTKPQVPRVSAAMGSQNASWQHQGMPNLSSQTSGNSSVNPFTAAPSFHIQQAHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPVSAQQRNSAPASAPPQAAPQQGLPGLSPSGPELGAFGQSPTSQMSGRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ

Target ORF information:

RefSeq Version	NM_175334.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus mastermind like transcriptional coactivator 1 (Maml1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175334.3

ORF Insert Sequence:

ATGGTGCTAC CCACCTGCCC CATGGCGGAG TTCGCGCTGC CGCGGCACAG CGCGGTCATG 
GAGCGCCTCC GCCGGCGCAT CGAACTGTGC CGGCGCCACC ACAGCACCTG TGAGGCCCGC 
TACGAGGCTG TGTCTCCCGA GCGCCTGGAG CTCGAGCGCC AGCACACCTT TGCCCTGCAC 
CAGCGCTGCA TCCAGGCCAA GGCCAAGCGC GCCGGCAAGC ACCGGCAGCC GCCGGCCGCC 
GCCACGGCCC CGGTTGCCGC TCCGGCCCCC GCCTCGGCCC CGGCGGCCGC GCGCCTGGAC 
GCAGCGGACG GCCCGGAGCA CGGCCGCCCG GTCGCGCATC TTCATGATAC AGTGAAGAGG 
AGTCTTGACA GTGCTGCCTC CCCTCAGAAT GGCGATCAAC CAAATGGCTA CGGAGACTTG 
TTTCCTGGGC ATAAGAAGAC ACGCCGGGAG GCCCCTCTGG GGGTCAGTGT GTCTGCCAAT 
GGGCTTCCTC CTGCCTCGCC CCTGGGCCAG CCCGACAAGC CTTCAGGGGG AGACACCCTG 
CAGACCGCTG GGAAGCACTC TCTGGGGCTC GATCCCATCA ACAAGAAGTG TCTGGCAGAC 
TCAGGCATCC ACCTGAATGG AGGCAGCAAC TCCAGTGAGC CCTTTCCTCT AAGCCTGAGT 
AAAGAACTCA AGCAGGAGCC AGTGGACGAC CTGCCGTGCA TGATCGCGGG CGCTGGAGGC 
TCCGTAGCTC AGAGCAACCT CATGCCGGAC CTCAACCTTA ATGAGCAGGA GTGGAAGGAG 
CTCATCGAGG AGCTCAACAG GTCAGTGCCC GACGAAGACA TGAAGGACCT GTTTACGGAG 
GACTTTGAGG AGAAGAAGGA TCCAGAGCCT CCTGGCTCTG CCACACAAAC CCCCCTGGCC 
CAGGACATTA ATATTAAGAC TGAGTTCTCT CCAGCAGCTT TTGAGCAGGA GCAGTTAGGT 
TCTCCACAAG TAAGGGCTGG GTCTGCAGGC CAGACCTTCC TAGGAGCCTC ATCTGCCCCT 
GTGGGCACAG ATTCTCCAAG CCTTGGGAGC TCTCAGACTC TGTTTCACAC AACTAGTCAA 
CCTGGGGTGG ATAATTCCAG TCCAAACCTG ATGCCGGCAT CAGCCCAGGC TCAAAGTGCA 
CAAAGAGCCC TCACGAGTGT GGTATTACCT AGCCAGGGCC CAGGCGGGGC CTCGGAGCTG 
TCCTCTGCTC ACCAGCTCCA GCAGATAGCT GCCAAGCAGA AGCGCGAGCA GATGTTGCAG 
AATCCCCAGC AAGCTGCCCC AGCACCCGGC CCAGGCCAGC TGGCCACGTG GCAGCAGGCA 
GGGCCCTCCC ACAGTCCCTT AGATGTTCCT TATCCCATGG AGAAGCCTGC CAGCCCTTCT 
GGCTACAAGC AAGACTTTAC CAACTCAAAA CTGCTCATGA TGCCCGGTGT GAACAAGAGT 
TCTCCTCGGC CAGGAGGCCC CTACCTCCAA CCTAGCCACT CCAACCTGCT GAGTCACCAG 
TCACCAAGTA ACTTGAATCA GAACCCCGTG AATAACCAAG GGTCTGTGCT AGACTATGGC 
AATACAAAGC CCCTTTCTCA TTACAAAGCA GACTGTGGCC AAGGTGGTCC TGGGTCTGGC 
CAGAACAAAC CAGCTTTGAT GGCATATCTT CCCCAGCAGC TGCCCCATCT GAGTAACGAG 
CAGAACTCCT TGTTTCTGAT GAAACCAAAG TCAGGAAACA TGCCCTTCCG GTCATTGGTT 
CCACCTGGCC AGGAGCAGAA CCCTTCCAGT GTCCCTGTAG CTGCCCCAGC TGCCAGTGTG 
GGAACCCAGC CTACTGTGTC TGTGGCCAGC ACTCACAACA GCTCGCCATA CCTCAGCAGC 
CAGCAGCAGG CAGCTGTGAT GAAGCAGCAC CAGCTGCTCC TGGACCAGCA GAAGCAGAGG 
GAGCAGCAGC AGCAGCAGCT GCAGCAGCAG CAGTTCCTGC AGAGGCAGCA CCTCCTGGCT 
GAGCAGGAGA AACAACAGTT TCAGCGTCAT CTGACCCGCC CACCCCCCCA GTACCAAGAC 
CCAACACAAA GCACCTTCCC ACAACAGGTT GGACAGTTCA CAGGACCTTC TGCTGCTGTG 
CCTGGGATGA ACAACTTGGG TCCGTCCAAC TCCAGCTGTC CTCGAGTGTT CCCTCAGCCT 
GGGACTCTGA TGTCCATGGG CCCTGGACAT GCCCCTGTCT CCTCTCTCCC CTCCAGCTCA 
GGCCAGCAGG ACCGTGGAGT GGCCCAGTTT ACTGGGTCCC AGAGTTTGCC TCAGAACAGC 
CTTTATGGCA TGGCATCTGG CCTAGCCCAG ATAGTTGCCC AGCCCCCACC ACAGGCTACC 
AGCACACATG CCCACATTCC ACGGCAGACC AACGTGGGCC AGAACGCCTC CACCTCGGCT 
GCATATGGAC AGAACTCTCT GGGGAGTGCC AGTCTTTCCC AGCAGCACAG TAAGGGAACC 
CTGCCTCCTG GTTTAACAAA GCCACAAGTC CCAAGGGTGT CAGCAGCCAT GGGAAGCCAG 
AATGCCTCGT GGCAGCATCA GGGAATGCCA AACCTGAGCA GCCAGACGTC TGGGAACAGC 
AGTGTGAACC CCTTCACTGC AGCTCCCAGT TTCCACATAC AGCAAGCCCA CCTGAAACTA 
GCTGGCCAGC AGTTCTCCCA AGCCATGCCC AGCAGGCCCA TGGCGCCTCT GAGTTCAGCA 
GGTGCAGCAG GGCCCATGCT GCCCCCAGTG AGTGCACAGC AGAGGAACAG TGCCCCTGCA 
TCTGCACCTC CCCAAGCAGC CCCGCAGCAG GGCTTGCCTG GCTTAAGTCC TTCGGGGCCC 
GAGCTGGGGG CCTTCGGCCA GAGCCCCACC TCCCAGATGA GCGGCCGGCC AGGGCTACAC 
TGTGCGCAGG CTTACCCTGT GAGGACCATG GGCCAAGAGC TGCCCTTTGC CTACAGCGGG 
CAGCCAGGTA GCAGTGGTCT GTCCAGTGTG GCTGGACACA CTGACCTGAT CGACTCGCTG 
CTGAAGAACA GGACTTCTGA GGAGTGGATC AATGAATTGG ATGATCTTTT AGGGTCACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Maml1 ( XM_006531918.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006531981.1 Mus musculus mastermind like 1 (Drosophila) (Maml1), transcript variant X1, mRNA.

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CloneID	OMu45361
Clone ID Related Accession (Same CDS sequence)	XM_006531918.3 , XM_006531918.4
Accession Version	XM_006531918.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3183bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	mastermind-like protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006531918.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTAC CCACCTGCCC CATGGCGGAG TTCGCGCTGC CGCGGCACAG CGCGGTCATG 
GAGCGCCTCC GCCGGCGCAT CGAACTGTGC CGGCGCCACC ACAGCACCTG TGAGGCCCGC 
TACGAGGCTG TGTCTCCCGA GCGCCTGGAG CTCGAGCGCC AGCACACCTT TGCCCTGCAC 
CAGCGCTGCA TCCAGGCCAA GGCCAAGCGC GCCGGCAAGC ACCGGCAGCC GCCGGCCGCC 
GCCACGGCCC CGGTTGCCGC TCCGGCCCCC GCCTCGGCCC CGGCGGCCGC GCGCCTGGAC 
GCAGCGGACG GCCCGGAGCA CGGCCGCCCG GTCGCGGGCT ATTGCTTTCC TTCCTTCCCA 
CACTATCCCC GCTGCGAGAC CACACGGCAG AACACACCGG TTCTGACCCA GCTGCTCGAG 
TCTTCTCATC CTCACTTTCC CGCCTGTAAA TCGAGGCATC TTCATGATAC AGTGAAGAGG 
AGTCTTGACA GTGCTGCCTC CCCTCAGAAT GGCGATCAAC CAAATGGCTA CGGAGACTTG 
TTTCCTGGGC ATAAGAAGAC ACGCCGGGAG GCCCCTCTGG GGGTCAGTGT GTCTGCCAAT 
GGGCTTCCTC CTGCCTCGCC CCTGGGCCAG CCCGACAAGC CTTCAGGGGG AGACACCCTG 
CAGACCGCTG GGAAGCACTC TCTGGGGCTC GATCCCATCA ACAAGAAGTG TCTGGCAGAC 
TCAGGCATCC ACCTGAATGG AGGCAGCAAC TCCAGTGAGC CCTTTCCTCT AAGCCTGAGT 
AAAGAACTCA AGCAGGAGCC AGTGGACGAC CTGCCGTGCA TGATCGCGGG CGCTGGAGGC 
TCCGTAGCTC AGAGCAACCT CATGCCGGAC CTCAACCTTA ATGAGCAGGA GTGGAAGGAG 
CTCATCGAGG AGCTCAACAG GTCAGTGCCC GACGAAGACA TGAAGGACCT GTTTACGGAG 
GACTTTGAGG AGAAGAAGGA TCCAGAGCCT CCTGGCTCTG CCACACAAAC CCCCCTGGCC 
CAGGACATTA ATATTAAGAC TGAGTTCTCT CCAGCAGCTT TTGAGCAGGA GCAGTTAGGT 
TCTCCACAAG TAAGGGCTGG GTCTGCAGGC CAGACCTTCC TAGGAGCCTC ATCTGCCCCT 
GTGGGCACAG ATTCTCCAAG CCTTGGGAGC TCTCAGACTC TGTTTCACAC AACTAGTCAA 
CCTGGGGTGG ATAATTCCAG TCCAAACCTG ATGCCGGCAT CAGCCCAGGC TCAAAGTGCA 
CAAAGAGCCC TCACGAGTGT GGTATTACCT AGCCAGGGCC CAGGCGGGGC CTCGGAGCTG 
TCCTCTGCTC ACCAGCTCCA GCAGATAGCT GCCAAGCAGA AGCGCGAGCA GATGTTGCAG 
AATCCCCAGC AAGCTGCCCC AGCACCCGGC CCAGGCCAGC TGGCCACGTG GCAGCAGGCA 
GGGCCCTCCC ACAGTCCCTT AGATGTTCCT TATCCCATGG AGAAGCCTGC CAGCCCTTCT 
GGCTACAAGC AAGACTTTAC CAACTCAAAA CTGCTCATGA TGCCCGGTGT GAACAAGAGT 
TCTCCTCGGC CAGGAGGCCC CTACCTCCAA CCTAGCCACT CCAACCTGCT GAGTCACCAG 
TCACCAAGTA ACTTGAATCA GAACCCCGTG AATAACCAAG GGTCTGTGCT AGACTATGGC 
AATACAAAGC CCCTTTCTCA TTACAAAGCA GACTGTGGCC AAGGTGGTCC TGGGTCTGGC 
CAGAACAAAC CAGCTTTGAT GGCATATCTT CCCCAGCAGC TGCCCCATCT GAGTAACGAG 
CAGAACTCCT TGTTTCTGAT GAAACCAAAG TCAGGAAACA TGCCCTTCCG GTCATTGGTT 
CCACCTGGCC AGGAGCAGAA CCCTTCCAGT GTCCCTGTAG CTGCCCCAGC TGCCAGTGTG 
GGAACCCAGC CTACTGTGTC TGTGGCCAGC ACTCACAACA GCTCGCCATA CCTCAGCAGC 
CAGCAGCAGG CAGCTGTGAT GAAGCAGCAC CAGCTGCTCC TGGACCAGCA GAAGCAGAGG 
GAGCAGCAGC AGCAGCAGCT GCAGCAGCAG CAGTTCCTGC AGAGGCAGCA CCTCCTGGCT 
GAGCAGGAGA AACAACAGTT TCAGCGTCAT CTGACCCGCC CACCCCCCCA GTACCAAGAC 
CCAACACAAA GCACCTTCCC ACAACAGGTT GGACAGTTCA CAGGACCTTC TGCTGCTGTG 
CCTGGGATGA ACAACTTGGG TCCGTCCAAC TCCAGCTGTC CTCGAGTGTT CCCTCAGCCT 
GGGACTCTGA TGTCCATGGG CCCTGGACAT GCCCCTGTCT CCTCTCTCCC CTCCAGCTCA 
GGCCAGCAGG ACCGTGGAGT GGCCCAGTTT ACTGGGTCCC AGAGTTTGCC TCAGAACAGC 
CTTTATGGCA TGGCATCTGG CCTAGCCCAG ATAGTTGCCC AGCCCCCACC ACAGGCTACC 
AGCACACATG CCCACATTCC ACGGCAGACC AACGTGGGCC AGAACGCCTC CACCTCGGCT 
GCATATGGAC AGAACTCTCT GGGGAGTGCC AGTCTTTCCC AGCAGCACAG TAAGGGAACC 
CTGCCTCCTG GTTTAACAAA GCCACAAGTC CCAAGGGTGT CAGCAGCCAT GGGAAGCCAG 
AATGCCTCGT GGCAGCATCA GGGAATGCCA AACCTGAGCA GCCAGACGTC TGGGAACAGC 
AGTGTGAACC CCTTCACTGC AGCTCCCAGT TTCCACATAC AGCAAGCCCA CCTGAAACTA 
GCTGGCCAGC AGTTCTCCCA AGCCATGCCC AGCAGGCCCA TGGCGCCTCT GAGTTCAGCA 
GGTGCAGCAG GGCCCATGCT GCCCCCAGTG AGTGCACAGC AGAGGAACAG TGCCCCTGCA 
TCTGCACCTC CCCAAGCAGC CCCGCAGCAG GGCTTGCCTG GCTTAAGTCC TTCGGGGCCC 
GAGCTGGGGG CCTTCGGCCA GAGCCCCACC TCCCAGATGA GCGGCCGGCC AGGGCTACAC 
TGTGCGCAGG CTTACCCTGT GAGGACCATG GGCCAAGAGC TGCCCTTTGC CTACAGCGGG 
CAGCCAGGTA GCAGTGGTCT GTCCAGTGTG GCTGGACACA CTGACCTGAT CGACTCGCTG 
CTGAAGAACA GGACTTCTGA GGAGTGGATC AATGAATTGG ATGATCTTTT AGGGTCACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006531981.1
CDS	1082..4264
Translation	MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRPVAGYCFPSFPHYPRCETTRQNTPVLTQLLESSHPHFPACKSRHLHDTVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGASSAPVGTDSPSLGSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNQNPVNNQGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVPVAAPAASVGTQPTVSVASTHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQQQLQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLTKPQVPRVSAAMGSQNASWQHQGMPNLSSQTSGNSSVNPFTAAPSFHIQQAHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPVSAQQRNSAPASAPPQAAPQQGLPGLSPSGPELGAFGQSPTSQMSGRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ

Target ORF information:

RefSeq Version	XM_006531918.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus mastermind like 1 (Drosophila) (Maml1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006531918.3

ORF Insert Sequence:

ATGGTGCTAC CCACCTGCCC CATGGCGGAG TTCGCGCTGC CGCGGCACAG CGCGGTCATG 
GAGCGCCTCC GCCGGCGCAT CGAACTGTGC CGGCGCCACC ACAGCACCTG TGAGGCCCGC 
TACGAGGCTG TGTCTCCCGA GCGCCTGGAG CTCGAGCGCC AGCACACCTT TGCCCTGCAC 
CAGCGCTGCA TCCAGGCCAA GGCCAAGCGC GCCGGCAAGC ACCGGCAGCC GCCGGCCGCC 
GCCACGGCCC CGGTTGCCGC TCCGGCCCCC GCCTCGGCCC CGGCGGCCGC GCGCCTGGAC 
GCAGCGGACG GCCCGGAGCA CGGCCGCCCG GTCGCGGGCT ATTGCTTTCC TTCCTTCCCA 
CACTATCCCC GCTGCGAGAC CACACGGCAG AACACACCGG TTCTGACCCA GCTGCTCGAG 
TCTTCTCATC CTCACTTTCC CGCCTGTAAA TCGAGGCATC TTCATGATAC AGTGAAGAGG 
AGTCTTGACA GTGCTGCCTC CCCTCAGAAT GGCGATCAAC CAAATGGCTA CGGAGACTTG 
TTTCCTGGGC ATAAGAAGAC ACGCCGGGAG GCCCCTCTGG GGGTCAGTGT GTCTGCCAAT 
GGGCTTCCTC CTGCCTCGCC CCTGGGCCAG CCCGACAAGC CTTCAGGGGG AGACACCCTG 
CAGACCGCTG GGAAGCACTC TCTGGGGCTC GATCCCATCA ACAAGAAGTG TCTGGCAGAC 
TCAGGCATCC ACCTGAATGG AGGCAGCAAC TCCAGTGAGC CCTTTCCTCT AAGCCTGAGT 
AAAGAACTCA AGCAGGAGCC AGTGGACGAC CTGCCGTGCA TGATCGCGGG CGCTGGAGGC 
TCCGTAGCTC AGAGCAACCT CATGCCGGAC CTCAACCTTA ATGAGCAGGA GTGGAAGGAG 
CTCATCGAGG AGCTCAACAG GTCAGTGCCC GACGAAGACA TGAAGGACCT GTTTACGGAG 
GACTTTGAGG AGAAGAAGGA TCCAGAGCCT CCTGGCTCTG CCACACAAAC CCCCCTGGCC 
CAGGACATTA ATATTAAGAC TGAGTTCTCT CCAGCAGCTT TTGAGCAGGA GCAGTTAGGT 
TCTCCACAAG TAAGGGCTGG GTCTGCAGGC CAGACCTTCC TAGGAGCCTC ATCTGCCCCT 
GTGGGCACAG ATTCTCCAAG CCTTGGGAGC TCTCAGACTC TGTTTCACAC AACTAGTCAA 
CCTGGGGTGG ATAATTCCAG TCCAAACCTG ATGCCGGCAT CAGCCCAGGC TCAAAGTGCA 
CAAAGAGCCC TCACGAGTGT GGTATTACCT AGCCAGGGCC CAGGCGGGGC CTCGGAGCTG 
TCCTCTGCTC ACCAGCTCCA GCAGATAGCT GCCAAGCAGA AGCGCGAGCA GATGTTGCAG 
AATCCCCAGC AAGCTGCCCC AGCACCCGGC CCAGGCCAGC TGGCCACGTG GCAGCAGGCA 
GGGCCCTCCC ACAGTCCCTT AGATGTTCCT TATCCCATGG AGAAGCCTGC CAGCCCTTCT 
GGCTACAAGC AAGACTTTAC CAACTCAAAA CTGCTCATGA TGCCCGGTGT GAACAAGAGT 
TCTCCTCGGC CAGGAGGCCC CTACCTCCAA CCTAGCCACT CCAACCTGCT GAGTCACCAG 
TCACCAAGTA ACTTGAATCA GAACCCCGTG AATAACCAAG GGTCTGTGCT AGACTATGGC 
AATACAAAGC CCCTTTCTCA TTACAAAGCA GACTGTGGCC AAGGTGGTCC TGGGTCTGGC 
CAGAACAAAC CAGCTTTGAT GGCATATCTT CCCCAGCAGC TGCCCCATCT GAGTAACGAG 
CAGAACTCCT TGTTTCTGAT GAAACCAAAG TCAGGAAACA TGCCCTTCCG GTCATTGGTT 
CCACCTGGCC AGGAGCAGAA CCCTTCCAGT GTCCCTGTAG CTGCCCCAGC TGCCAGTGTG 
GGAACCCAGC CTACTGTGTC TGTGGCCAGC ACTCACAACA GCTCGCCATA CCTCAGCAGC 
CAGCAGCAGG CAGCTGTGAT GAAGCAGCAC CAGCTGCTCC TGGACCAGCA GAAGCAGAGG 
GAGCAGCAGC AGCAGCAGCT GCAGCAGCAG CAGTTCCTGC AGAGGCAGCA CCTCCTGGCT 
GAGCAGGAGA AACAACAGTT TCAGCGTCAT CTGACCCGCC CACCCCCCCA GTACCAAGAC 
CCAACACAAA GCACCTTCCC ACAACAGGTT GGACAGTTCA CAGGACCTTC TGCTGCTGTG 
CCTGGGATGA ACAACTTGGG TCCGTCCAAC TCCAGCTGTC CTCGAGTGTT CCCTCAGCCT 
GGGACTCTGA TGTCCATGGG CCCTGGACAT GCCCCTGTCT CCTCTCTCCC CTCCAGCTCA 
GGCCAGCAGG ACCGTGGAGT GGCCCAGTTT ACTGGGTCCC AGAGTTTGCC TCAGAACAGC 
CTTTATGGCA TGGCATCTGG CCTAGCCCAG ATAGTTGCCC AGCCCCCACC ACAGGCTACC 
AGCACACATG CCCACATTCC ACGGCAGACC AACGTGGGCC AGAACGCCTC CACCTCGGCT 
GCATATGGAC AGAACTCTCT GGGGAGTGCC AGTCTTTCCC AGCAGCACAG TAAGGGAACC 
CTGCCTCCTG GTTTAACAAA GCCACAAGTC CCAAGGGTGT CAGCAGCCAT GGGAAGCCAG 
AATGCCTCGT GGCAGCATCA GGGAATGCCA AACCTGAGCA GCCAGACGTC TGGGAACAGC 
AGTGTGAACC CCTTCACTGC AGCTCCCAGT TTCCACATAC AGCAAGCCCA CCTGAAACTA 
GCTGGCCAGC AGTTCTCCCA AGCCATGCCC AGCAGGCCCA TGGCGCCTCT GAGTTCAGCA 
GGTGCAGCAG GGCCCATGCT GCCCCCAGTG AGTGCACAGC AGAGGAACAG TGCCCCTGCA 
TCTGCACCTC CCCAAGCAGC CCCGCAGCAG GGCTTGCCTG GCTTAAGTCC TTCGGGGCCC 
GAGCTGGGGG CCTTCGGCCA GAGCCCCACC TCCCAGATGA GCGGCCGGCC AGGGCTACAC 
TGTGCGCAGG CTTACCCTGT GAGGACCATG GGCCAAGAGC TGCCCTTTGC CTACAGCGGG 
CAGCCAGGTA GCAGTGGTCT GTCCAGTGTG GCTGGACACA CTGACCTGAT CGACTCGCTG 
CTGAAGAACA GGACTTCTGA GGAGTGGATC AATGAATTGG ATGATCTTTT AGGGTCACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway.
Cell death & disease8(7)e2942(2017 Jul)
Quaranta R,Pelullo M,Zema S,Nardozza F,Checquolo S,Lauer DM,Bufalieri F,Palermo R,Felli MP,Vacca A,Talora C,Di Marcotullio L,Screpanti I,Bellavia D

Olfactory Sensory Neurons Control Dendritic Complexity of Mitral Cells via Notch Signaling.
PLoS genetics12(12)e1006514(2016 Dec)
Muroyama Y,Baba A,Kitagawa M,Saito T

Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway.
Development (Cambridge, England)143(12)2160-71(2016 06)
Grisanti L,Revenkova E,Gordon RE,Iomini C

CbGRiTS: cerebellar gene regulation in time and space.
Developmental biology397(1)18-30(2015 Jan)
Ha T,Swanson D,Larouche M,Glenn R,Weeden D,Zhang P,Hamre K,Langston M,Phillips C,Song M,Ouyang Z,Chesler E,Duvvurru S,Yordanova R,Cui Y,Campbell K,Ricker G,Phillips C,Homayouni R,Goldowitz D

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

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Maml1 cDNA ORF clone, Mus musculus(house mouse)

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Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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