Upb1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Upb1
Entrez Gene ID	103149
Full Name	ureidopropionase, beta
Synonyms	AI195023
General protein information	Preferred Names ureidopropionase, beta Names beta-ureidopropionase N-carbamoyl-beta-alanine amidohydrolase beta-alanine synthase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 C1
Summary	This gene encodes an enzyme that catalyzes the conversion of N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid or beta-alanine. Mutations in the related gene in human have been associated with beta-ureidopropionase deficiency. [provided by RefSeq, Dec 2013].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133995.4	NP_598756.1	beta-ureidopropionase

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Upb1	NP_598756.1
	UPB1	XP_001095304.2
Rattus norvegicus (Norway rat)	Upb1	NP_446297.1
Danio rerio (zebrafish)	upb1	NP_955910.1
Oryza sativa (rice)	Os07g0485100	NP_001059656.1
Pan troglodytes (chimpanzee)	UPB1	XP_003953895.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010229	XP_319417.2
Arabidopsis thaliana (thale cress)	BETA-UP	NP_201242.2
Gallus gallus (chicken)	UPB1	XP_415242.1
Xenopus tropicalis (tropical clawed frog)	upb1	NP_001120264.1
Homo sapiens (human)	UPB1	NP_057411.1
Canis lupus familiaris (dog)	UPB1	XP_543524.2
Bos taurus (cattle)	UPB1	NP_001094520.1
Drosophila melanogaster (fruit fly)	pyd3	NP_649732.1
Caenorhabditis elegans (roundworm)	upb-1	NP_495261.1

Gene Ontology
Bibliography

Related articles in PubMed

The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers.
Harten SK, Oey H, Bourke LM, Bharti V, Isbel L, Daxinger L, Faou P, Robertson N, Matthews JM, Whitelaw E
BMC biology1321(2015 Mar)

Beta-alanine synthase, an enzyme involved in catabolism of uracil and thymine.
Traut TW
Methods in enzymology324399-410(2000)

Cloning, sequencing, and expression of a cDNA encoding beta-alanine synthase from rat liver.
Kvalnes-Krick KL, Traut TW
The Journal of biological chemistry268(8)5686-93(1993 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

cloning and characterization of rat ortholog
Title: Cloning, sequencing, and expression of a cDNA encoding beta-alanine synthase from rat liver.

The following Upb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Upb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10437	NM_133995.4 Latest version!	Mus musculus ureidopropionase, beta (Upb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Upb1 ( NM_133995.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598756.1 Mus musculus ureidopropionase, beta (Upb1), mRNA.

Price & Availability↑

CloneID	OMu10437
Clone ID Related Accession (Same CDS sequence)	NM_133995.4
Accession Version	NM_133995.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1182bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	beta-ureidopropionase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC137067.33 and AK149480.1. On Dec 19, 2013 this sequence version replaced NM_133995.3. ##Evidence-Data-START## Transcript exon combination :: AK149480.1, AK149373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849378 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGAC CGGAGTGGCA GTCCCTGGAG CAGTGCCTGG AAAAACATCT GCCGCCTGAC 
GATTTGGCCC AGGTGAAGCG AATTCTCTAC GGCAAGCAGA CTAGGAATCT CGATCTGCCC 
AGAGAAGCTT TAAAAGCTGC CTCAGAAAGG AACTTTGAAC TGAAGGGATA TGCCTTCGGG 
GCAGCCAAGG AGCAGCAGAG ATGCCCCCAG ATCGTGCGCG TGGGGCTCGT TCAGAACAGA 
ATCCCGCTCC CCACTTCTGC CCCCGTGGCA GAACAGGTCT CTGCGCTCCA CAAGAGCATA 
GAGGAGATTG CTGAGGTGGC CGCAATGTGT GGAGTCAATA TCATCTGTTT CCAGGAAGCA 
TGGAATATGC CGTTCGCTTT TTGTACACGA GAGAAACTTC CTTGGACAGA ATTTGCTGAG 
TCGGCCGAGG ATGGGCTCAC CACCAGGTTC TGTCAGAAGC TGGCAAAGAA GCACAACATG 
GTGGTGGTGT CTCCAATCTT GGAGCGTGAT AGAGAGCATG GGGGAGTTCT GTGGAACACA 
GCTGTGGTGA TCTCCAATTC AGGGCTGGTC ATGGGGAAGA CCAGAAAGAA CCACATCCCC 
AGAGTGGGAG ACTTCAACGA GTCCACTTAC TACATGGAGG GAAACCTGGG CCACCCCGTG 
TTCCAGACCC AGTTTGGCAG GATTGCAGTG AACATTTGCT ATGGGCGGCA CCACCCCCTC 
AACTGGCTCA TGTACAGCAT CAACGGAGCT GAAATCATCT TCAACCCTTC GGCCACCATT 
GGAGAACTCA GTGAGTCCTT GTGGCCGATC GAAGCCAGAA ATGCAGCCAT TGCCAATCAC 
TGCTTCACCT GTGCTCTCAA CCGTGTGGGT CAGGAACACT TCCCCAATGA GTTTACTTCT 
GGAGATGGAA AGAAAGCTCA CCATGACCTC GGCTACTTCT ATGGTTCGAG CTATGTGGCA 
GCTCCCGATG GCAGCCGGAC CCCCGGCCTC TCCCGTAATC AGGATGGGCT GCTGGTCACG 
GAGCTCAACC TCAATCTCTG CCAGCAGATC AATGATTTCT GGACTTTCAA GATGACGGGA 
CGACTTGAGA TGTATGCCCG GGAACTTGCC GAAGCGGTCA AACCCAACTA CAGTCCCAAC 
ATTGTGAAGG AAGACCTGGT ACTAGCCCCT AGCTCGGGTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598756.1
CDS	146..1327
Translation	MAGPEWQSLEQCLEKHLPPDDLAQVKRILYGKQTRNLDLPREALKAASERNFELKGYAFGAAKEQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKSIEEIAEVAAMCGVNIICFQEAWNMPFAFCTREKLPWTEFAESAEDGLTTRFCQKLAKKHNMVVVSPILERDREHGGVLWNTAVVISNSGLVMGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCALNRVGQEHFPNEFTSGDGKKAHHDLGYFYGSSYVAAPDGSRTPGLSRNQDGLLVTELNLNLCQQINDFWTFKMTGRLEMYARELAEAVKPNYSPNIVKEDLVLAPSSG

Target ORF information:

RefSeq Version	NM_133995.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ureidopropionase, beta (Upb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133995.4

ORF Insert Sequence:

ATGGCGGGAC CGGAGTGGCA GTCCCTGGAG CAGTGCCTGG AAAAACATCT GCCGCCTGAC 
GATTTGGCCC AGGTGAAGCG AATTCTCTAC GGCAAGCAGA CTAGGAATCT CGATCTGCCC 
AGAGAAGCTT TAAAAGCTGC CTCAGAAAGG AACTTTGAAC TGAAGGGATA TGCCTTCGGG 
GCAGCCAAGG AGCAGCAGAG ATGCCCCCAG ATCGTGCGCG TGGGGCTCGT TCAGAACAGA 
ATCCCGCTCC CCACTTCTGC CCCCGTGGCA GAACAGGTCT CTGCGCTCCA CAAGAGCATA 
GAGGAGATTG CTGAGGTGGC CGCAATGTGT GGAGTCAATA TCATCTGTTT CCAGGAAGCA 
TGGAATATGC CGTTCGCTTT TTGTACACGA GAGAAACTTC CTTGGACAGA ATTTGCTGAG 
TCGGCCGAGG ATGGGCTCAC CACCAGGTTC TGTCAGAAGC TGGCAAAGAA GCACAACATG 
GTGGTGGTGT CTCCAATCTT GGAGCGTGAT AGAGAGCATG GGGGAGTTCT GTGGAACACA 
GCTGTGGTGA TCTCCAATTC AGGGCTGGTC ATGGGGAAGA CCAGAAAGAA CCACATCCCC 
AGAGTGGGAG ACTTCAACGA GTCCACTTAC TACATGGAGG GAAACCTGGG CCACCCCGTG 
TTCCAGACCC AGTTTGGCAG GATTGCAGTG AACATTTGCT ATGGGCGGCA CCACCCCCTC 
AACTGGCTCA TGTACAGCAT CAACGGAGCT GAAATCATCT TCAACCCTTC GGCCACCATT 
GGAGAACTCA GTGAGTCCTT GTGGCCGATC GAAGCCAGAA ATGCAGCCAT TGCCAATCAC 
TGCTTCACCT GTGCTCTCAA CCGTGTGGGT CAGGAACACT TCCCCAATGA GTTTACTTCT 
GGAGATGGAA AGAAAGCTCA CCATGACCTC GGCTACTTCT ATGGTTCGAG CTATGTGGCA 
GCTCCCGATG GCAGCCGGAC CCCCGGCCTC TCCCGTAATC AGGATGGGCT GCTGGTCACG 
GAGCTCAACC TCAATCTCTG CCAGCAGATC AATGATTTCT GGACTTTCAA GATGACGGGA 
CGACTTGAGA TGTATGCCCG GGAACTTGCC GAAGCGGTCA AACCCAACTA CAGTCCCAAC 
ATTGTGAAGG AAGACCTGGT ACTAGCCCCT AGCTCGGGTT AG