Exoc8 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Exoc8
Entrez Gene ID	102058
Full Name	exocyst complex component 8
Synonyms	AI414418,EXO84,Exo84p,R74783,SEC84
General protein information	Preferred Names exocyst complex component 8 Names exocyst complex component 8 exocyst complex 84 kDa subunit
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_198103.2	NP_932771.1	exocyst complex component 8

Pathways from BioSystems

Homologies

	EXOC8	XP_001104940.1
Gallus gallus (chicken)	EXOC8	NP_001006404.1
Homo sapiens (human)	EXOC8	NP_787072.2
Canis lupus familiaris (dog)	EXOC8	XP_005618878.1
Danio rerio (zebrafish)	exoc8	NP_001103945.1
Pan troglodytes (chimpanzee)	EXOC8	XP_513085.1
Mus musculus (house mouse)	Exoc8	NP_932771.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004207	XP_313109.5
Bos taurus (cattle)	EXOC8	NP_001091581.1
Rattus norvegicus (Norway rat)	Exoc8	NP_620612.1
Caenorhabditis elegans (roundworm)	exoc-8	NP_001021702.1
Drosophila melanogaster (fruit fly)	exo84	NP_651454.1
Xenopus tropicalis (tropical clawed frog)	exoc8	XP_002941641.1

Gene Ontology
Bibliography

Related articles in PubMed

Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking.
Uhm M, Bazuine M, Zhao P, Chiang SH, Xiong T, Karunanithi S, Chang L, Saltiel AR
Science signaling10(471)(2017 Mar)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Arl13b and the exocyst interact synergistically in ciliogenesis.
Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T, Lipschutz JH, Barral DC
Molecular biology of the cell27(2)308-20(2016 Jan)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Phosphoproteomic analysis of the developing mouse brain.
Ballif BA, Vill?n J, Beausoleil SA, Schwartz D, Gygi SP
Molecular & cellular proteomics : MCP3(11)1093-101(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that TBK1 directly interacts with Exo84 through the coiled-coil domain of TBK1 and helical domain of Exo84, and knockdown of TBK1 blocked insulin-stimulated glucose uptake and GLUT4 translocation.
Title: Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking.

The following Exoc8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Exoc8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58175	NM_198103.2 Latest version!	Mus musculus exocyst complex component 8 (Exoc8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$419.30 $599.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Exoc8 ( NM_198103.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_932771.1 Mus musculus exocyst complex component 8 (Exoc8), mRNA.

Price & Availability↑

CloneID	OMu58175
Clone ID Related Accession (Same CDS sequence)	NM_198103.2
Accession Version	NM_198103.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2151bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	exocyst complex component 8
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC057052.1, AK054047.1, AC151736.6 and BC094378.1. On Aug 4, 2006 this sequence version replaced NM_198103.1. COMPLETENESS: complete on the 3' end.

ATGTCGGACA GCGGGGCGAG CCGCCTGCGG AGGCAGCTGG AGTCGGGGGG CTTCGAGGCG 
CGGCTGTACG TGAAGCAACT GTCGCAGCAG TCGGACGGCG ACCGCGACCT GCAGGAGCAC 
CGGCAGCGGG TGCAGGCGCT GGCAGAGGAG ACGGCACAGA ACCTGAAGCG CAACGTCTAC 
CAGAACTACC GGCAGTTCAT CGAGACGGCG CGGGAGATCT CCTACCTGGA GAGCGAAATG 
TACCAGCTGA GCCACCTGCT GACTGAGCAG AAGAGCAGCC TGGAGAGCAT CCCGCTGGCA 
CTGCTGCCCG CCGCCGCCGC GGGCGCCTCT GCGGGTGAGG ACACGGCCGG CGCGGGGCCG 
CGGGAGCGCG GGGCGGTCCA GGCGGGCTTC CTGCCCGGGC CGGCGGGCGT CCCTCGAGAG 
GGTTCCGGGA CGGGCGAGGA GGGCAAGCAG CGAACGCTCA CCACGCTGCT GGAGAAGGTG 
GAGGGCTGCA GGGACCTGTT GGAGACGCCA GGTCAGTACC TGGTGTACAA CGGGGACCTG 
GTGGAATACG ATGCGGACCA CATGGCCCAG CTGCAGCGCG TGCACGGCTT CCTCATGAAC 
GACTGTCTGC TGGTGGCCAC CTGGCTGCCA CAACGGCGAG GCATGTACCG CTACAACGCA 
CTCTACCCGC TGGACCGCCT GGCGGTGGTC AACGTCAAAG ACAATCCGCC CATGAAAGAC 
ATGTTCAAGC TTCTCATGTT CCCCGAGAGC CGAATCTTCC AGGCGGAAAA TGCCAAGATC 
AAGCGCGAGT GGCTGGAAGT GCTGGAGGAA ACCAAGAGGG CCCTCAGCGA CAAGAGGAGG 
CGGGAGCAGG AGGAGGCAGC AGCCCCGCGT GCGCCACCAC CGGTCACTTC CAAGGGCAGC 
AACCCGTTTG AGGACGAGGA TGATGAAGAA CTGGCCACCC CTGAGGCGGA GGAGGAAAAG 
GTTGACCTTT CCATGGAGTG GATCCAAGAG CTGCCGGAAG ACTTGGATGT TTGTATTGCA 
CAGAGGGACT TTGAGGGTGC CGTGGACTTG CTGGACAAAT TAAATCACTA CCTGGAAGAT 
AAGCCCAGCC CACCTCCTGT GAAAGAGCTG AGGGCCAAAG TGGACGAACG AGTGCGACAG 
CTCACCGAGG TGCTTGTGTT TGAGCTCTCC CCGGATCGCT CTCTGAGAGG CGGCCCCAAG 
GCTACTCGGA GAGCCGTGTC TCAGCTGATC CGGCTGGGCC AGTGCACGAA GGCTTGCGAG 
CTGTTTCTGA GGAACAGGGC CGCAGCCGTG CACACTGCCA TCCGCCAGCT CAGGATTGAG 
GGCGCCACGC TGCTCTACAT TCACAAGCTG TGCCACGTCT TCTTTACCAG CCTCCTAGAG 
ACCGCGAGAG AGTTTGAGAC GGACTTTGCA GGCACTGACA GTGGCTGCTA CTCTGCCTTT 
GTGGTCTGGG CAAGGTCGGC CATGGGCATG TTCGTGGATG CTTTCAGCAA GCAGGTTTTT 
GACAGCAAGG AGAGCCTGTC CACCGCTGCT GAGTGTGTGA AGGTGGCCAA GGAGCACTGC 
CAGCAGCTGG GAGAGATTGG GCTGGACCTC ACCTTCATCA TCCACGCCCT GCTGGTGAAG 
GACATCCAGG GCGCCCTGCA CAGTTACAAG GAGATTATCA TTGAAGCCAC CAAGCACCGA 
AACTCGGAGG AGATGTGGCG CCGCATGAAC CTGATGACTC CTGAGGCCCT GGGCAAGCTC 
AAGGAGGAGA TGAAAAGTTG CGGGGTCAGT AACTTTGAGC AGTACACGGG AGATGACTGC 
TGGGTGAACT TGAGCTACAC GGTGGTAGCC TTCACCAAGC AGACTATGGG CTTCCTGGAG 
GAGGCATTGA AACTGTACTT CCCTGAGCTC CACATGGTGC TCCTGGAGAG CCTGGTAGAA 
ATCATCCTGG TGGCTGTGCA GCATGTGGAC TACAGCCTGC GCTGTGAGCA GGACCCCGAG 
AAGAAGGCCT TCATCAGGCA GAACGCATCC TTTCTCTATG AAACTGTCCT CCCGGTGGTG 
GAGAGGAGGT TTGAGGAAGG TGTGGGGAAG CCCGCCAAGC AGCTGCAGGA CCTCCGGAAC 
GCATCCCGGC TCCTGCGGGT GAATCCCGAG AGCACGACTT CTGTGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_932771.1
CDS	80..2230
Translation	MSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRVQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLALLPAAAAGASAGEDTAGAGPRERGAVQAGFLPGPAGVPREGSGTGEEGKQRTLTTLLEKVEGCRDLLETPGQYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYPLDRLAVVNVKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEETKRALSDKRRREQEEAAAPRAPPPVTSKGSNPFEDEDDEELATPEAEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLEDKPSPPPVKELRAKVDERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIRLGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFETDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGEIGLDLTFIIHALLVKDIQGALHSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSNFEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDYSLRCEQDPEKKAFIRQNASFLYETVLPVVERRFEEGVGKPAKQLQDLRNASRLLRVNPESTTSVV

Target ORF information:

RefSeq Version	NM_198103.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus exocyst complex component 8 (Exoc8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198103.2

ORF Insert Sequence:

ATGTCGGACA GCGGGGCGAG CCGCCTGCGG AGGCAGCTGG AGTCGGGGGG CTTCGAGGCG 
CGGCTGTACG TGAAGCAACT GTCGCAGCAG TCGGACGGCG ACCGCGACCT GCAGGAGCAC 
CGGCAGCGGG TGCAGGCGCT GGCAGAGGAG ACGGCACAGA ACCTGAAGCG CAACGTCTAC 
CAGAACTACC GGCAGTTCAT CGAGACGGCG CGGGAGATCT CCTACCTGGA GAGCGAAATG 
TACCAGCTGA GCCACCTGCT GACTGAGCAG AAGAGCAGCC TGGAGAGCAT CCCGCTGGCA 
CTGCTGCCCG CCGCCGCCGC GGGCGCCTCT GCGGGTGAGG ACACGGCCGG CGCGGGGCCG 
CGGGAGCGCG GGGCGGTCCA GGCGGGCTTC CTGCCCGGGC CGGCGGGCGT CCCTCGAGAG 
GGTTCCGGGA CGGGCGAGGA GGGCAAGCAG CGAACGCTCA CCACGCTGCT GGAGAAGGTG 
GAGGGCTGCA GGGACCTGTT GGAGACGCCA GGTCAGTACC TGGTGTACAA CGGGGACCTG 
GTGGAATACG ATGCGGACCA CATGGCCCAG CTGCAGCGCG TGCACGGCTT CCTCATGAAC 
GACTGTCTGC TGGTGGCCAC CTGGCTGCCA CAACGGCGAG GCATGTACCG CTACAACGCA 
CTCTACCCGC TGGACCGCCT GGCGGTGGTC AACGTCAAAG ACAATCCGCC CATGAAAGAC 
ATGTTCAAGC TTCTCATGTT CCCCGAGAGC CGAATCTTCC AGGCGGAAAA TGCCAAGATC 
AAGCGCGAGT GGCTGGAAGT GCTGGAGGAA ACCAAGAGGG CCCTCAGCGA CAAGAGGAGG 
CGGGAGCAGG AGGAGGCAGC AGCCCCGCGT GCGCCACCAC CGGTCACTTC CAAGGGCAGC 
AACCCGTTTG AGGACGAGGA TGATGAAGAA CTGGCCACCC CTGAGGCGGA GGAGGAAAAG 
GTTGACCTTT CCATGGAGTG GATCCAAGAG CTGCCGGAAG ACTTGGATGT TTGTATTGCA 
CAGAGGGACT TTGAGGGTGC CGTGGACTTG CTGGACAAAT TAAATCACTA CCTGGAAGAT 
AAGCCCAGCC CACCTCCTGT GAAAGAGCTG AGGGCCAAAG TGGACGAACG AGTGCGACAG 
CTCACCGAGG TGCTTGTGTT TGAGCTCTCC CCGGATCGCT CTCTGAGAGG CGGCCCCAAG 
GCTACTCGGA GAGCCGTGTC TCAGCTGATC CGGCTGGGCC AGTGCACGAA GGCTTGCGAG 
CTGTTTCTGA GGAACAGGGC CGCAGCCGTG CACACTGCCA TCCGCCAGCT CAGGATTGAG 
GGCGCCACGC TGCTCTACAT TCACAAGCTG TGCCACGTCT TCTTTACCAG CCTCCTAGAG 
ACCGCGAGAG AGTTTGAGAC GGACTTTGCA GGCACTGACA GTGGCTGCTA CTCTGCCTTT 
GTGGTCTGGG CAAGGTCGGC CATGGGCATG TTCGTGGATG CTTTCAGCAA GCAGGTTTTT 
GACAGCAAGG AGAGCCTGTC CACCGCTGCT GAGTGTGTGA AGGTGGCCAA GGAGCACTGC 
CAGCAGCTGG GAGAGATTGG GCTGGACCTC ACCTTCATCA TCCACGCCCT GCTGGTGAAG 
GACATCCAGG GCGCCCTGCA CAGTTACAAG GAGATTATCA TTGAAGCCAC CAAGCACCGA 
AACTCGGAGG AGATGTGGCG CCGCATGAAC CTGATGACTC CTGAGGCCCT GGGCAAGCTC 
AAGGAGGAGA TGAAAAGTTG CGGGGTCAGT AACTTTGAGC AGTACACGGG AGATGACTGC 
TGGGTGAACT TGAGCTACAC GGTGGTAGCC TTCACCAAGC AGACTATGGG CTTCCTGGAG 
GAGGCATTGA AACTGTACTT CCCTGAGCTC CACATGGTGC TCCTGGAGAG CCTGGTAGAA 
ATCATCCTGG TGGCTGTGCA GCATGTGGAC TACAGCCTGC GCTGTGAGCA GGACCCCGAG 
AAGAAGGCCT TCATCAGGCA GAACGCATCC TTTCTCTATG AAACTGTCCT CCCGGTGGTG 
GAGAGGAGGT TTGAGGAAGG TGTGGGGAAG CCCGCCAAGC AGCTGCAGGA CCTCCGGAAC 
GCATCCCGGC TCCTGCGGGT GAATCCCGAG AGCACGACTT CTGTGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking.
Science signaling10(471)(2017 Mar)
Uhm M,Bazuine M,Zhao P,Chiang SH,Xiong T,Karunanithi S,Chang L,Saltiel AR

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Arl13b and the exocyst interact synergistically in ciliogenesis.
Molecular biology of the cell27(2)308-20(2016 Jan)
Seixas C,Choi SY,Polgar N,Umberger NL,East MP,Zuo X,Moreiras H,Ghossoub R,Benmerah A,Kahn RA,Fogelgren B,Caspary T,Lipschutz JH,Barral DC

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Phosphoproteomic analysis of the developing mouse brain.
Molecular & cellular proteomics : MCP3(11)1093-101(2004 Nov)
Ballif BA,Vill?n J,Beausoleil SA,Schwartz D,Gygi SP

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Exoc8 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報