Iqschfp cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Iqschfp
Entrez Gene ID	100505386
Full Name	predicted gene, 21949
Synonyms	Iqcj-schip1,Schip-1-iqcj,Schip1
General protein information	Preferred Names predicted gene, 21949 Names IQCJ-SCHIP1 readthrough transcript protein IQ motif containing J-schwannomin interacting protein 1 fusion protein IQ motif containing J-schwannomin interacting protein 1 readthrough schwannomin interacting protein 1 isoform IQCJ schwannomin interacting protein 1 isoform IQCJs
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 E1\|3
Summary	This locus represents naturally occurring read-through transcription from the neighboring IQ motif containing J (Iqcj) and schwannomin interacting protein 1 (Schip1) genes. This locus produces a transcript that is composed of in-frame exons from each individual gene. The resulting fusion protein is thought to be a component of the multimolecular complexes of axon initial segments and nodes of Ranvier, and it may play a role in calcium-mediated responses. [provided by RefSeq, Oct 2010].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001113419.2	NP_001106890.1	IQCJ-SCHIP1 readthrough transcript protein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SCHIP1	NP_001229984.1
Danio rerio (zebrafish)	schip1	NP_001017906.1
Homo sapiens (human)	IQCJ-SCHIP1	NP_001184042.1
Rattus norvegicus (Norway rat)	Schip1	NP_001094136.1
Gallus gallus (chicken)	SCHIP1	XP_004943575.1
Canis lupus familiaris (dog)	SCHIP1	XP_003434180.1
Mus musculus (house mouse)	Gm21949	NP_001106890.1

Gene Ontology
Bibliography

Related articles in PubMed

Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.
Martin PM, Cifuentes-Diaz C, Devaux J, Garcia M, Bureau J, Thomasseau S, Klingler E, Girault JA, Goutebroze L
The Journal of biological chemistry292(6)2441-2456(2017 02)

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.
Papandr?ou MJ, Vacher H, Fache MP, Klingler E, Rueda-Boroni F, Ferracci G, Debarnot C, Pip?roglou C, Garcia Del Ca?o G, Goutebroze L, Dargent B
Journal of neurochemistry134(3)527-37(2015 Aug)

Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.
Martin PM, Carnaud M, Garcia del Ca?o G, Irondelle M, Irinopoulou T, Girault JA, Dargent B, Goutebroze L
The Journal of neuroscience : the official journal of the Society for Neuroscience28(24)6111-7(2008 Jun)

IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.
Kwa?nicka-Crawford DA, Carson AR, Scherer SW
Biochemical and biophysical research communications350(4)890-9(2006 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Iqschfp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Iqschfp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu05075	NM_001113419.2 Latest version!	Mus musculus Iqcj and Schip1 fusion protein (Iqschfp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Iqschfp ( NM_001113419.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001106890.1 Mus musculus Iqcj and Schip1 fusion protein (Iqschfp), mRNA.

Price & Availability↑

CloneID	OMu05075
Clone ID Related Accession (Same CDS sequence)	NM_001113419.2
Accession Version	NM_001113419.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	IQCJ-SCHIP1 readthrough transcript protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124370.3, AC093360.7, AC122913.4 and AC121306.12. On Oct 7, 2010 this sequence version replaced NM_001113419.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: EU163409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 30953, 208426 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGACTGG AAGAACTAAA GAGACTACAG AATCCTTTAG AACAAGTTGA CGATGGAAAA 
TATTTGCTTG AGAATCACCA GCTGGCCATG GATGTGGAGA ATAACATTGA GAACTATCCC 
CTCAGCCTAC AGCCCTTGGA ATCAAAGGTG AAAATCATCC AGCGAGCATG GCGAGAGTAC 
TTGCAGAGGC AGGACCCCCT GGAGAAGCGG AGCCCATCCC CACCTTCTGT CTCTTCAGAC 
AAGCTGAGCA GCTCTGTCAG CATGAACACC TTCTCCGACA GCAGCACACC CGATTACCGA 
GAGGATGGGA TGGATCTAGG CAGTGACGCC GGCAGCAGCA GCAGCAGCCG CGCCAGCTCA 
CAATCCAACT CCACCAAAGT GACCCCTTGC TCCGAGTGCA AATCCTCATC GTCGCCGGGG 
GGTAGCTTGG ACTTGGTGTC TGCTCTGGAA GACTATGAAG AGCCCTTCCC GGTCTACCAG 
AAGAAGGTGA TTGATGAGTG GGCTCCGGAG GAGGACGGGG AGGAGGAGGA AGAGGAGGAC 
GATCGAGGGT ATCGGGATGA CGGCTGTCCG GCCCGGGAGC CGGGGGACGT GAGCGCCAGG 
ATCGGCAGCA GCGGCAGCGG GAGCAGGAGC GCCGCCACCA CCATGCCGTC CCCGATGCCT 
AACGGCAACC TCCATCCGCA CGACCCTCAA GACCTCAGGC ACAATGGCAA CGTGGTGGTA 
GCTGGCCGGC CGAACGCCTC TCGGGTTCCC CGGCGACCCA TCCAGAAGAC CCAGCCTCCA 
GGGAGCCGGC GCGGAGGCCG AAACCGGGCA TCTGGGGGCC TCTGCCTTCA GCCACCGGAC 
GGCGGGACGC GGGTCCCGGA AGAACCCCCT GCGCCCCCAA TGGACTGGGA GGCATTGGAA 
AAGCATCTGG CCGGGCTGCA GTTCCGGGAG CAGGAGGTGC GAAACCAGGG TCAGGCGAGG 
ACCAACTCCA CCTCTGCACA GAAGAATGAG AGAGAGTCTA TCAGACAGAA GTTGGCACTC 
GGAAGCTTCT TTGACGATGG CCCAGGAATC TATACCAGCT GCAGCAAAAG TGGGAAGCCA 
AGCCTTTCTG CAAGACTACA GAGCGGGATG AACCTCCAGA TATGCTTTGT CAATGACAGC 
GGCAGTGACA AGGACAGCGA TGCAGATGAC AGTAAGACGG AAACCAGCTT GGACACGCCC 
TTGTCCCCCA TGAGCAAGCA GAGTTCTTCC TATTCGGATA GAGACACAAC TGAGGAGGAG 
TCTGAATCCC TGGATGACAT GGACTTCCTC ACAAGGCAAA AGAAGCTACA AGCTGAAGCC 
AAAATGGCTC TGGCCATGGC CAAACCAATG GCCAAAATGC AAGTAGAAGT GGAAAAACAG 
AACAGGAAAA AGTCTCCCGT CGCTGATCTT CTCCCACACA TGCCTCACAT AAGCGAATGT 
TTGATGAAAA GAAGCTTAAA GCCCACCGAC CTGAGAGACA TGACTATCGG GCAGCTACAA 
GTGATCGTCA ATGACCTCCA CTCCCAGATT GAAAGTTTGA ATGAAGAGTT GGTCCAGCTG 
CTCCTTATTC GAGATGAGCT GCACACAGAA CAAGATGCCA TGCTGGTGGA CATTGAAGAC 
TTGACTAGAC ACGCTGAGAG TCAGCAGAAG CACATGGCTG AGAAAATGCC CGCGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106890.1
CDS	94..1773
Translation	MRLEELKRLQNPLEQVDDGKYLLENHQLAMDVENNIENYPLSLQPLESKVKIIQRAWREYLQRQDPLEKRSPSPPSVSSDKLSSSVSMNTFSDSSTPDYREDGMDLGSDAGSSSSSRASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGEEEEEEDDRGYRDDGCPAREPGDVSARIGSSGSGSRSAATTMPSPMPNGNLHPHDPQDLRHNGNVVVAGRPNASRVPRRPIQKTQPPGSRRGGRNRASGGLCLQPPDGGTRVPEEPPAPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSARLQSGMNLQICFVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHMPHISECLMKRSLKPTDLRDMTIGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHMAEKMPAK

Target ORF information:

RefSeq Version	NM_001113419.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus Iqcj and Schip1 fusion protein (Iqschfp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001113419.2

ORF Insert Sequence:

ATGCGACTGG AAGAACTAAA GAGACTACAG AATCCTTTAG AACAAGTTGA CGATGGAAAA 
TATTTGCTTG AGAATCACCA GCTGGCCATG GATGTGGAGA ATAACATTGA GAACTATCCC 
CTCAGCCTAC AGCCCTTGGA ATCAAAGGTG AAAATCATCC AGCGAGCATG GCGAGAGTAC 
TTGCAGAGGC AGGACCCCCT GGAGAAGCGG AGCCCATCCC CACCTTCTGT CTCTTCAGAC 
AAGCTGAGCA GCTCTGTCAG CATGAACACC TTCTCCGACA GCAGCACACC CGATTACCGA 
GAGGATGGGA TGGATCTAGG CAGTGACGCC GGCAGCAGCA GCAGCAGCCG CGCCAGCTCA 
CAATCCAACT CCACCAAAGT GACCCCTTGC TCCGAGTGCA AATCCTCATC GTCGCCGGGG 
GGTAGCTTGG ACTTGGTGTC TGCTCTGGAA GACTATGAAG AGCCCTTCCC GGTCTACCAG 
AAGAAGGTGA TTGATGAGTG GGCTCCGGAG GAGGACGGGG AGGAGGAGGA AGAGGAGGAC 
GATCGAGGGT ATCGGGATGA CGGCTGTCCG GCCCGGGAGC CGGGGGACGT GAGCGCCAGG 
ATCGGCAGCA GCGGCAGCGG GAGCAGGAGC GCCGCCACCA CCATGCCGTC CCCGATGCCT 
AACGGCAACC TCCATCCGCA CGACCCTCAA GACCTCAGGC ACAATGGCAA CGTGGTGGTA 
GCTGGCCGGC CGAACGCCTC TCGGGTTCCC CGGCGACCCA TCCAGAAGAC CCAGCCTCCA 
GGGAGCCGGC GCGGAGGCCG AAACCGGGCA TCTGGGGGCC TCTGCCTTCA GCCACCGGAC 
GGCGGGACGC GGGTCCCGGA AGAACCCCCT GCGCCCCCAA TGGACTGGGA GGCATTGGAA 
AAGCATCTGG CCGGGCTGCA GTTCCGGGAG CAGGAGGTGC GAAACCAGGG TCAGGCGAGG 
ACCAACTCCA CCTCTGCACA GAAGAATGAG AGAGAGTCTA TCAGACAGAA GTTGGCACTC 
GGAAGCTTCT TTGACGATGG CCCAGGAATC TATACCAGCT GCAGCAAAAG TGGGAAGCCA 
AGCCTTTCTG CAAGACTACA GAGCGGGATG AACCTCCAGA TATGCTTTGT CAATGACAGC 
GGCAGTGACA AGGACAGCGA TGCAGATGAC AGTAAGACGG AAACCAGCTT GGACACGCCC 
TTGTCCCCCA TGAGCAAGCA GAGTTCTTCC TATTCGGATA GAGACACAAC TGAGGAGGAG 
TCTGAATCCC TGGATGACAT GGACTTCCTC ACAAGGCAAA AGAAGCTACA AGCTGAAGCC 
AAAATGGCTC TGGCCATGGC CAAACCAATG GCCAAAATGC AAGTAGAAGT GGAAAAACAG 
AACAGGAAAA AGTCTCCCGT CGCTGATCTT CTCCCACACA TGCCTCACAT AAGCGAATGT 
TTGATGAAAA GAAGCTTAAA GCCCACCGAC CTGAGAGACA TGACTATCGG GCAGCTACAA 
GTGATCGTCA ATGACCTCCA CTCCCAGATT GAAAGTTTGA ATGAAGAGTT GGTCCAGCTG 
CTCCTTATTC GAGATGAGCT GCACACAGAA CAAGATGCCA TGCTGGTGGA CATTGAAGAC 
TTGACTAGAC ACGCTGAGAG TCAGCAGAAG CACATGGCTG AGAAAATGCC CGCGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.
The Journal of biological chemistry292(6)2441-2456(2017 02)
Martin PM,Cifuentes-Diaz C,Devaux J,Garcia M,Bureau J,Thomasseau S,Klingler E,Girault JA,Goutebroze L

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.
Journal of neurochemistry134(3)527-37(2015 Aug)
Papandr?ou MJ,Vacher H,Fache MP,Klingler E,Rueda-Boroni F,Ferracci G,Debarnot C,Pip?roglou C,Garcia Del Ca?o G,Goutebroze L,Dargent B

Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.
The Journal of neuroscience : the official journal of the Society for Neuroscience28(24)6111-7(2008 Jun)
Martin PM,Carnaud M,Garcia del Ca?o G,Irondelle M,Irinopoulou T,Girault JA,Dargent B,Goutebroze L

IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.
Biochemical and biophysical research communications350(4)890-9(2006 Dec)
Kwa?nicka-Crawford DA,Carson AR,Scherer SW

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Iqschfp cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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