Gene Symbol | DLEC1 |
Entrez Gene ID | 9940 |
Full Name | deleted in lung and esophageal cancer 1 |
Synonyms | CFAP81,DLC-1,DLC1,F56 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The cytogenetic location of this gene is 3p21.3, and it is located in a region that is commonly deleted in a variety of malignancies. Down-regulation of this gene has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of this gene in tumor cells is a result of aberrant promoter methylation. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins.[provided by RefSeq, Mar 2016]. |
Disorder MIM: | |
Disorder Html: | Lung cancer, 211980 (1); Esophageal cancer, 133239 (1) |