KLHL21 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KLHL21
Entrez Gene ID	9903
Full Name	kelch like family member 21
General protein information	Preferred Names kelch like family member 21 Names kelch-like protein 21
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.31
Disorder MIM:	616262

mRNA and Protein(s)

mRNA	Protein	Name
NM_014851.3	NP_055666.2	kelch-like protein 21 isoform 1
NM_001324309.1	NP_001311238.1	kelch-like protein 21 isoform 2
NM_014851.4	NP_055666.2	kelch-like protein 21 isoform 1
NM_001324309.2	NP_001311238.1	kelch-like protein 21 isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	KLHL21	NP_001070279.1
Homo sapiens (human)	KLHL21	NP_055666.2
	KLHL21	XP_001094118.1
Canis lupus familiaris (dog)	KLHL21	XP_546754.2
Danio rerio (zebrafish)	klhl21	NP_996964.1
Xenopus tropicalis (tropical clawed frog)	klhl21	XP_004916251.1
Pan troglodytes (chimpanzee)	KLHL21	XP_514342.2
Mus musculus (house mouse)	Klhl21	NP_001028524.1
Rattus norvegicus (Norway rat)	Klhl21	NP_001101466.1
Gallus gallus (chicken)	KLHL21	XP_003642565.1

Gene Ontology
Bibliography

Related articles in PubMed

KLHL21, a novel gene that contributes to the progression of hepatocellular carcinoma.
Shi L, Zhang W, Zou F, Mei L, Wu G, Teng Y
BMC cancer16(1)815(2016 10)

Kelch-like Protein 21 (KLHL21) Targets I?B Kinase-? to Regulate Nuclear Factor ?-Light Chain Enhancer of Activated B Cells (NF-?B) Signaling Negatively.
Mei ZZ, Chen XY, Hu SW, Wang N, Ou XL, Wang J, Luo HH, Liu J, Jiang Y
The Journal of biological chemistry291(35)18176-89(2016 08)

Update on the Kelch-like (KLHL) gene family.
Dhanoa BS, Cogliati T, Satish AG, Bruford EA, Friedman JS
Human genomics713(2013 May)

The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.
Maerki S, Olma MH, Staubli T, Steigemann P, Gerlich DW, Quadroni M, Sumara I, Peter M
The Journal of cell biology187(6)791-800(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our study suggests that KLHL21 is a potential target for therapeutic intervention. Our findings also provide novel candidate genes on a genome-wide scale, which may have significant impact on the design and execution of effective therapy of HCC patients.
Title: KLHL21, a novel gene that contributes to the progression of hepatocellular carcinoma.

data clearly demonstrate that KLHL21 negatively regulates TNFalpha-activated NF-kappaB signaling via targeting IKKbeta, providing new insight into the mechanisms underlying NF-kappaB regulation in cells.
Title: Kelch-like Protein 21 (KLHL21) Targets I?B Kinase-? to Regulate Nuclear Factor ?-Light Chain Enhancer of Activated B Cells (NF-?B) Signaling Negatively.

KLHL21 localizes to midzone microtubules in anaphase & recruits aurora B & Cul3 to this region; results suggest that different Cul3 adaptors nonredundantly regulate aurora B during mitosis, possibly by ubiquitinating different pools of aurora B
Title: The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.

The following KLHL21 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KLHL21 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu34016	NM_001324309.2 Latest version!	Homo sapiens kelch like family member 21 (KLHL21), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu63484	NM_014851.4 Latest version!	Homo sapiens kelch like family member 21 (KLHL21), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
View Old Accession Versions >>
OHu63484	NM_014851.3	Homo sapiens kelch like family member 21 (KLHL21), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
OHu34016	NM_001324309.1	Homo sapiens kelch like family member 21 (KLHL21), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KLHL21 ( NM_001324309.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311238.1 Homo sapiens kelch like family member 21 (KLHL21), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu34016
Clone ID Related Accession (Same CDS sequence)	NM_001324309.1 , NM_001324309.2
Accession Version	NM_001324309.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1503bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	kelch-like protein 21 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL591866.13. On Apr 29, 2016 this sequence version replaced XM_005263542.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.254429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 
GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC 
TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC 
GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG 
GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC 
GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC 
ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC 
ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC 
CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG 
CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG 
CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC 
GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC 
CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG 
TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG 
CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC 
CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG 
GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT 
GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG 
GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC 
TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC 
CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC 
TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC 
TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT 
GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311238.1
CDS	82..1584
Translation	MERPAPLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAADLLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRFILRHVGELGAEQLERLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAHWPQLLEAVRLPFVRRFYLLAHVEAEPLVARCPPCLRLLREARDFQAARYDRHDRGPCPRMRPRPSTGLAEILVLVGGCDQDCDELVTVDCYNPQTGQWRYLAEFPDHLGGGYSIVALGNDIYVTGGSDGSRLYDCVWRYNSSVNEWAEVAPMLKAREYHSSSVLDGLLYVVAADSTERYDHTTDSWEALQPMTYPMDNCSTTACRGRLYAIGSLAGKETMVMQCYDPDTDLWSLVDCGQLPPWSFAPKTATLNGLMYFVRDDSAEVDVYNPTRNEWDKIPSMNQ

Target ORF information:

RefSeq Version	NM_001324309.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kelch like family member 21 (KLHL21), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324309.1

ORF Insert Sequence:

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 
GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC 
TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC 
GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG 
GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC 
GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC 
ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC 
ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC 
CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG 
CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG 
CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC 
GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC 
CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG 
TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG 
CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC 
CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG 
GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT 
GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG 
GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC 
TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC 
CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC 
TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC 
TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT 
GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLHL21 ( NM_001324309.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311238.1 Homo sapiens kelch like family member 21 (KLHL21), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu34016
Clone ID Related Accession (Same CDS sequence)	NM_001324309.1 , NM_001324309.2
Accession Version	NM_001324309.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1503bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	kelch-like protein 21 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL591866.13. On May 31, 2019 this sequence version replaced NM_001324309.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.254429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 
GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC 
TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC 
GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG 
GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC 
GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC 
ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC 
ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC 
CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG 
CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG 
CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC 
GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC 
CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG 
TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG 
CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC 
CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG 
GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT 
GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG 
GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC 
TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC 
CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC 
TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC 
TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT 
GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311238.1
CDS	53..1555
Translation	MERPAPLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAADLLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRFILRHVGELGAEQLERLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAHWPQLLEAVRLPFVRRFYLLAHVEAEPLVARCPPCLRLLREARDFQAARYDRHDRGPCPRMRPRPSTGLAEILVLVGGCDQDCDELVTVDCYNPQTGQWRYLAEFPDHLGGGYSIVALGNDIYVTGGSDGSRLYDCVWRYNSSVNEWAEVAPMLKAREYHSSSVLDGLLYVVAADSTERYDHTTDSWEALQPMTYPMDNCSTTACRGRLYAIGSLAGKETMVMQCYDPDTDLWSLVDCGQLPPWSFAPKTATLNGLMYFVRDDSAEVDVYNPTRNEWDKIPSMNQ

Target ORF information:

RefSeq Version	NM_001324309.2
Organism	Homo sapiens(human)
Definition	Homo sapiens kelch like family member 21 (KLHL21), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324309.2

ORF Insert Sequence:

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 
GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC 
TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC 
GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG 
GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC 
GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC 
ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC 
ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC 
CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG 
CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG 
CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC 
GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC 
CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG 
TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG 
CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC 
CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG 
GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT 
GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG 
GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC 
TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC 
CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC 
TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC 
TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT 
GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLHL21 ( NM_014851.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055666.2 Homo sapiens kelch like family member 21 (KLHL21), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu63484
Clone ID Related Accession (Same CDS sequence)	NM_014851.3 , NM_014851.4
Accession Version	NM_014851.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	kelch-like protein 21 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB007938.1 and BC064980.1. On Dec 14, 2014 this sequence version replaced NM_014851.2. ##Evidence-Data-START## Transcript exon combination :: BC034039.1, AK075305.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 
GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC 
TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC 
GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG 
GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC 
GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC 
ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC 
ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC 
CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG 
CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG 
CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC 
GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC 
CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG 
TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG 
CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC 
CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG 
GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT 
GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG 
GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC 
TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC 
CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC 
TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC 
TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT 
GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG 
GTACATGTGG GGGGCAGCCT GGCCGTCCTT GGGGGGAAGC TGTACGTCTC TGGGGGATAC 
GACAATACAT TTGAACTCTC GGACGTGGTA GAGGCCTATG ACCCAGAGAC TCGCGCGTGG 
AGCGTGGTGG GGCGGCTCCC AGAACCCACC TTCTGGCATG GCAGTGTCAG CATCTTCCGC 
CAGTTCATGC CCCAGACCTT CTCGGGTGGG CGTGGCTTCG AGTTGGACAG TGGCAGCGAT 
GACATGGACC CAGGCCGACC CCGGCCGCCG CGGGACCCCG ATGAGCTGCA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055666.2
CDS	82..1875
Translation	MERPAPLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAADLLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRFILRHVGELGAEQLERLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAHWPQLLEAVRLPFVRRFYLLAHVEAEPLVARCPPCLRLLREARDFQAARYDRHDRGPCPRMRPRPSTGLAEILVLVGGCDQDCDELVTVDCYNPQTGQWRYLAEFPDHLGGGYSIVALGNDIYVTGGSDGSRLYDCVWRYNSSVNEWAEVAPMLKAREYHSSSVLDGLLYVVAADSTERYDHTTDSWEALQPMTYPMDNCSTTACRGRLYAIGSLAGKETMVMQCYDPDTDLWSLVDCGQLPPWSFAPKTATLNGLMYFVRDDSAEVDVYNPTRNEWDKIPSMNQVHVGGSLAVLGGKLYVSGGYDNTFELSDVVEAYDPETRAWSVVGRLPEPTFWHGSVSIFRQFMPQTFSGGRGFELDSGSDDMDPGRPRPPRDPDELH

Target ORF information:

RefSeq Version	NM_014851.3
Organism	Homo sapiens(human)
Definition	Homo sapiens kelch like family member 21 (KLHL21), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014851.3

ORF Insert Sequence:

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 
GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC 
TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC 
GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG 
GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC 
GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC 
ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC 
ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC 
CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG 
CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG 
CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC 
GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC 
CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG 
TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG 
CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC 
CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG 
GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT 
GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG 
GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC 
TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC 
CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC 
TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC 
TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT 
GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG 
GTACATGTGG GGGGCAGCCT GGCCGTCCTT GGGGGGAAGC TGTACGTCTC TGGGGGATAC 
GACAATACAT TTGAACTCTC GGACGTGGTA GAGGCCTATG ACCCAGAGAC TCGCGCGTGG 
AGCGTGGTGG GGCGGCTCCC AGAACCCACC TTCTGGCATG GCAGTGTCAG CATCTTCCGC 
CAGTTCATGC CCCAGACCTT CTCGGGTGGG CGTGGCTTCG AGTTGGACAG TGGCAGCGAT 
GACATGGACC CAGGCCGACC CCGGCCGCCG CGGGACCCCG ATGAGCTGCA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLHL21 ( NM_014851.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055666.2 Homo sapiens kelch like family member 21 (KLHL21), transcript variant 1, mRNA.

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CloneID	OHu63484
Clone ID Related Accession (Same CDS sequence)	NM_014851.3 , NM_014851.4
Accession Version	NM_014851.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	kelch-like protein 21 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB007938.1 and BC064980.1. On Nov 23, 2018 this sequence version replaced NM_014851.3. ##Evidence-Data-START## Transcript exon combination :: BC034039.1, AK075305.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377658.8/ ENSP00000366886.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 
GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC 
TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC 
GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG 
GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC 
GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC 
ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC 
ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC 
CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG 
CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG 
CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC 
GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC 
CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG 
TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG 
CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC 
CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG 
GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT 
GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG 
GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC 
TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC 
CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC 
TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC 
TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT 
GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG 
GTACATGTGG GGGGCAGCCT GGCCGTCCTT GGGGGGAAGC TGTACGTCTC TGGGGGATAC 
GACAATACAT TTGAACTCTC GGACGTGGTA GAGGCCTATG ACCCAGAGAC TCGCGCGTGG 
AGCGTGGTGG GGCGGCTCCC AGAACCCACC TTCTGGCATG GCAGTGTCAG CATCTTCCGC 
CAGTTCATGC CCCAGACCTT CTCGGGTGGG CGTGGCTTCG AGTTGGACAG TGGCAGCGAT 
GACATGGACC CAGGCCGACC CCGGCCGCCG CGGGACCCCG ATGAGCTGCA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055666.2
CDS	53..1846
Translation	MERPAPLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAADLLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRFILRHVGELGAEQLERLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAHWPQLLEAVRLPFVRRFYLLAHVEAEPLVARCPPCLRLLREARDFQAARYDRHDRGPCPRMRPRPSTGLAEILVLVGGCDQDCDELVTVDCYNPQTGQWRYLAEFPDHLGGGYSIVALGNDIYVTGGSDGSRLYDCVWRYNSSVNEWAEVAPMLKAREYHSSSVLDGLLYVVAADSTERYDHTTDSWEALQPMTYPMDNCSTTACRGRLYAIGSLAGKETMVMQCYDPDTDLWSLVDCGQLPPWSFAPKTATLNGLMYFVRDDSAEVDVYNPTRNEWDKIPSMNQVHVGGSLAVLGGKLYVSGGYDNTFELSDVVEAYDPETRAWSVVGRLPEPTFWHGSVSIFRQFMPQTFSGGRGFELDSGSDDMDPGRPRPPRDPDELH

Target ORF information:

RefSeq Version	NM_014851.4
Organism	Homo sapiens(human)
Definition	Homo sapiens kelch like family member 21 (KLHL21), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014851.4

ORF Insert Sequence:

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 
GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC 
TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC 
GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG 
GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC 
GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC 
ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC 
ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC 
CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG 
CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG 
CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC 
GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC 
CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG 
TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG 
CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC 
CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG 
GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT 
GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG 
GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC 
TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC 
CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC 
TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC 
TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT 
GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG 
GTACATGTGG GGGGCAGCCT GGCCGTCCTT GGGGGGAAGC TGTACGTCTC TGGGGGATAC 
GACAATACAT TTGAACTCTC GGACGTGGTA GAGGCCTATG ACCCAGAGAC TCGCGCGTGG 
AGCGTGGTGG GGCGGCTCCC AGAACCCACC TTCTGGCATG GCAGTGTCAG CATCTTCCGC 
CAGTTCATGC CCCAGACCTT CTCGGGTGGG CGTGGCTTCG AGTTGGACAG TGGCAGCGAT 
GACATGGACC CAGGCCGACC CCGGCCGCCG CGGGACCCCG ATGAGCTGCA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

KLHL21, a novel gene that contributes to the progression of hepatocellular carcinoma.
BMC cancer16(1)815(2016 10)
Shi L,Zhang W,Zou F,Mei L,Wu G,Teng Y

Kelch-like Protein 21 (KLHL21) Targets I?B Kinase-? to Regulate Nuclear Factor ?-Light Chain Enhancer of Activated B Cells (NF-?B) Signaling Negatively.
The Journal of biological chemistry291(35)18176-89(2016 08)
Mei ZZ,Chen XY,Hu SW,Wang N,Ou XL,Wang J,Luo HH,Liu J,Jiang Y

Update on the Kelch-like (KLHL) gene family.
Human genomics713(2013 May)
Dhanoa BS,Cogliati T,Satish AG,Bruford EA,Friedman JS

The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.
The Journal of cell biology187(6)791-800(2009 Dec)
Maerki S,Olma MH,Staubli T,Steigemann P,Gerlich DW,Quadroni M,Sumara I,Peter M

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KLHL21 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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