Gene Symbol | LRIG2 |
Entrez Gene ID | 9860 |
Full Name | leucine rich repeats and immunoglobulin like domains 2 |
Synonyms | LIG-2,LIG2,UFS2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]. |
Disorder MIM: | |
Disorder Html: | Urofacial syndrome 2, 615112 (3) |