ECE2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ECE2
Entrez Gene ID	9718
Full Name	endothelin converting enzyme 2
General protein information	Preferred Names endothelin converting enzyme 2 Names endothelin-converting enzyme 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q27.1
Disorder MIM:	610145

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100120.1	NP_001093590.1	endothelin-converting enzyme 2 isoform D
NM_001100121.1	NP_001093591.1	endothelin-converting enzyme 2 isoform E
NM_001037324.2	NP_001032401.1	endothelin-converting enzyme 2 isoform B
NM_001100121.2	NP_001093591.1	endothelin-converting enzyme 2 isoform E
NM_001037324.3	NP_001032401.1	endothelin-converting enzyme 2 isoform B
NM_001100120.2	NP_001093590.1	endothelin-converting enzyme 2 isoform D

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ECE2	XP_005639826.1
Mus musculus (house mouse)	Ece2	NP_808810.1
Homo sapiens (human)	ECE2	NP_055508.3
	ECE2	XP_001098704.2
Drosophila melanogaster (fruit fly)	Nep1	NP_727065.1
Magnaporthe oryzae (rice blast fungus)	MGG_06643	XP_003709345.1
Bos taurus (cattle)	ECE2	NP_808871.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009791	XP_553645.3
Caenorhabditis elegans (roundworm)	nep-11	NP_494538.1
Rattus norvegicus (Norway rat)	Ece2	NP_001002815.2
Gallus gallus (chicken)	ECE2	XP_004943462.1
Pan troglodytes (chimpanzee)	ECE2	XP_001147750.1
Caenorhabditis elegans (roundworm)	nep-1	NP_496490.2
Xenopus tropicalis (tropical clawed frog)	ece2	XP_002935189.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1.
Smith-Anttila CJA, Bensing S, Alimohammadi M, Dalin F, Oscarson M, Zhang MD, Perheentupa J, Husebye ES, Gustafsson J, Bj?rklund P, Fransson A, Nordmark G, R?nnblom L, Meloni A, Scott RJ, H?kfelt T, Crock PA, K?mpe O
Autoimmunity50(4)223-231(2017 Jun)

Endothelin-converting enzymes degrade ?-synuclein and are reduced in dementia with Lewy bodies.
Miners JS, Love S
Journal of neurochemistry141(2)275-286(2017 Apr)

A mega-analysis of genome-wide association studies for major depressive disorder.
, Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, M?ller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, Slager SL, Smit JH, Stefansson H, Steffens M, Thorgeirsson T, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, V?lzke H, Weilburg JB, Willemsen G, Zitman FG, Neale B, Daly M, Levinson DF, Sullivan PF
Molecular psychiatry18(4)497-511(2013 Apr)

The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk.
Hamilton G, Harris SE, Davies G, Liewald DC, Tenesa A, Payton A, Horan MA, Ollier WE, Pendleton N, , Starr JM, Porteous D, Deary IJ
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics159B(6)696-709(2012 Sep)

Genetic analysis of genes involved in amyloid-? degradation and clearance in Alzheimer's disease.
Natunen T, Helisalmi S, Veps?l?inen S, Saraj?rvi T, Antikainen L, M?kinen P, Herukka SK, Koivisto AM, Haapasalo A, Soininen H, Hiltunen M
Journal of Alzheimer's disease : JAD28(3)553-9(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ECE-2 and ECE-1 levels are significantly reduced in post-mortem brain from dementia with Lewy body patients.
Title: Endothelin-converting enzymes degrade ?-synuclein and are reduced in dementia with Lewy bodies.

Te results of this study suggested taht genetic variations in MMEL1, ECE1, ECE2, AGER, PLG, PLAT, NR1H3, MMP3, LRP1, TTR, NR1H2, and MMP9 genes do not play major role among the Finnish AD patient cohort.
Title: Genetic analysis of genes involved in amyloid-? degradation and clearance in Alzheimer's disease.

The PL405 assay is thus the first tool to study ECE-2 inhibition using high throughput screening or for ex vivo ECE-2 quantification.
Title: Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay.

Observational study of gene-disease association. (HuGE Navigator)
Title: Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.

Abeta accumulation in Alzheimer's disease is unlikely to be caused by ECE-2 deficiency. However, ECE-2 expression is up-regulated
Title: Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta.

The following ECE2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ECE2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18010	NM_001100121.2 Latest version!	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$538.30 $769.00
OHu18608	NM_001100120.2 Latest version!	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$573.30 $819.00
OHu18714	NM_001037324.3 Latest version!	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
View Old Accession Versions >>
OHu18010	NM_001100121.1	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$538.30 $769.00
OHu18714	NM_001037324.2	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu18608	NM_001100120.1	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$573.30 $819.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ECE2 ( NM_001100121.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093591.1 Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu18010
Clone ID Related Accession (Same CDS sequence)	NM_001100121.1 , NM_001100121.2
Accession Version	NM_001100121.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2298bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-20
Organism	Homo sapiens(human)
Product	endothelin-converting enzyme 2 isoform E
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC142950.1, AF192531.1, AY359003.1 and AF428263.1. Transcript Variant: This variant (5) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (E) has a distinct N-terminus compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.60881.1, AB011176.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACA TGGTGGAGTA CAAACGGGCC 
ACGCTTCGGG ATGAAGACGC ACCCGAGACC CCCGTAGAGG GCGGGGCCTC CCCGGACGCC 
ATGGAGGTGG GATTCCAGAA GGGGACAAGA CAGCTGTTAG GCTCACGCAC GCAGCTGGAG 
CTGGTCTTAG CAGGTGCCTC TCTACTGCTG GCTGCACTGC TTCTGGGCTG CCTTGTGGCC 
CTAGGGGTCC AGTACCACAG AGACCCATCC CACAGCACCT GCCTTACAGA GGCCTGCATT 
CGAGTGGCTG GAAAAATCCT GGAGTCCCTG GACCGAGGGG TGAGCCCCTG TGAGGACTTT 
TACCAGTTCT CCTGTGGGGG CTGGATTCGG AGGAACCCCC TGCCCGATGG GCGTTCTCGC 
TGGAACACCT TCAACAGCCT CTGGGACCAA AACCAGGCCA TACTGAAGCA CCTGCTTGAA 
AACACCACCT TCAACTCCAG CAGTGAAGCT GAGCAGAAGA CACAGCGCTT CTACCTATCT 
TGCCTACAGG TGGAGCGCAT TGAGGAGCTG GGAGCCCAGC CACTGAGAGA CCTCATTGAG 
AAGATTGGTG GTTGGAACAT TACGGGGCCC TGGGACCAGG ACAACTTTAT GGAGGTGTTG 
AAGGCAGTAG CAGGGACCTA CAGGGCCACC CCATTCTTCA CCGTCTACAT CAGTGCCGAC 
TCTAAGAGTT CCAACAGCAA TGTTATCCAG GTGGACCAGT CTGGGCTCTT TCTGCCCTCT 
CGGGATTACT ACTTAAACAG AACTGCCAAT GAGAAAGTGC TCACTGCCTA TCTGGATTAC 
ATGGAGGAAC TGGGGATGCT GCTGGGTGGG CGGCCCACCT CCACGAGGGA GCAGATGCAG 
CAGGTGCTGG AGTTGGAGAT ACAGCTGGCC AACATCACAG TGCCCCAGGA CCAGCGGCGC 
GACGAGGAGA AGATCTACCA CAAGATGAGC ATTTCGGAGC TGCAGGCTCT GGCGCCCTCC 
ATGGACTGGC TTGAGTTCCT GTCTTTCTTG CTGTCACCAT TGGAGTTGAG TGACTCTGAG 
CCTGTGGTGG TGTATGGGAT GGATTATTTG CAGCAGGTGT CAGAGCTCAT CAACCGCACG 
GAACCAAGCA TCCTGAACAA TTACCTGATC TGGAACCTGG TGCAAAAGAC AACCTCAAGC 
CTGGACCGAC GCTTTGAGTC TGCACAAGAG AAGCTGCTGG AGACCCTCTA TGGCACTAAG 
AAGTCCTGTG TGCCGAGGTG GCAGACCTGC ATCTCCAACA CGGATGACGC CCTTGGCTTT 
GCTTTGGGGT CCCTCTTCGT GAAGGCCACG TTTGACCGGC AAAGCAAAGA AATTGCAGAG 
GGGATGATCA GCGAAATCCG GACCGCATTT GAGGAGGCCC TGGGACAGCT GGTTTGGATG 
GATGAGAAGA CCCGCCAGGC AGCCAAGGAG AAAGCAGATG CCATCTATGA TATGATTGGT 
TTCCCAGACT TTATCCTGGA GCCCAAAGAG CTGGATGATG TTTATGACGG GTACGAAATT 
TCTGAAGATT CTTTCTTCCA AAACATGTTG AATTTGTACA ACTTCTCTGC CAAGGTTATG 
GCTGACCAGC TCCGCAAGCC TCCCAGCCGA GACCAGTGGA GCATGACCCC CCAGACAGTG 
AATGCCTACT ACCTTCCAAC TAAGAATGAG ATCGTCTTCC CCGCTGGCAT CCTGCAGGCC 
CCCTTCTATG CCCGCAACCA CCCCAAGGCC CTGAACTTCG GTGGCATCGG TGTGGTCATG 
GGCCATGAGT TGACGCATGC CTTTGATGAC CAAGGGCGCG AGTATGACAA AGAAGGGAAC 
CTGCGGCCCT GGTGGCAGAA TGAGTCCCTG GCAGCCTTCC GGAACCACAC GGCCTGCATG 
GAGGAACAGT ACAATCAATA CCAGGTCAAT GGGGAGAGGC TCAACGGCCG CCAGACGCTG 
GGGGAGAACA TTGCTGACAA CGGGGGGCTG AAGGCTGCCT ACAATGCTTA CAAAGCATGG 
CTGAGAAAGC ATGGGGAGGA GCAGCAACTG CCAGCCGTGG GGCTCACCAA CCACCAGCTC 
TTCTTCGTGG GATTTGCCCA GGTGTGGTGC TCGGTCCGCA CACCAGAGAG CTCTCACGAG 
GGGCTGGTGA CCGACCCCCA CAGCCCTGCC CGCTTCCGCG TGCTGGGCAC TCTCTCCAAC 
TCCCGTGACT TCCTGCGGCA CTTCGGCTGC CCTGTCGGCT CCCCCATGAA CCCAGGGCAG 
CTGTGTGAGG TGTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093591.1
CDS	144..2441
Translation	MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW

Target ORF information:

RefSeq Version	NM_001100121.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100121.1

ORF Insert Sequence:

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACA TGGTGGAGTA CAAACGGGCC 
ACGCTTCGGG ATGAAGACGC ACCCGAGACC CCCGTAGAGG GCGGGGCCTC CCCGGACGCC 
ATGGAGGTGG GATTCCAGAA GGGGACAAGA CAGCTGTTAG GCTCACGCAC GCAGCTGGAG 
CTGGTCTTAG CAGGTGCCTC TCTACTGCTG GCTGCACTGC TTCTGGGCTG CCTTGTGGCC 
CTAGGGGTCC AGTACCACAG AGACCCATCC CACAGCACCT GCCTTACAGA GGCCTGCATT 
CGAGTGGCTG GAAAAATCCT GGAGTCCCTG GACCGAGGGG TGAGCCCCTG TGAGGACTTT 
TACCAGTTCT CCTGTGGGGG CTGGATTCGG AGGAACCCCC TGCCCGATGG GCGTTCTCGC 
TGGAACACCT TCAACAGCCT CTGGGACCAA AACCAGGCCA TACTGAAGCA CCTGCTTGAA 
AACACCACCT TCAACTCCAG CAGTGAAGCT GAGCAGAAGA CACAGCGCTT CTACCTATCT 
TGCCTACAGG TGGAGCGCAT TGAGGAGCTG GGAGCCCAGC CACTGAGAGA CCTCATTGAG 
AAGATTGGTG GTTGGAACAT TACGGGGCCC TGGGACCAGG ACAACTTTAT GGAGGTGTTG 
AAGGCAGTAG CAGGGACCTA CAGGGCCACC CCATTCTTCA CCGTCTACAT CAGTGCCGAC 
TCTAAGAGTT CCAACAGCAA TGTTATCCAG GTGGACCAGT CTGGGCTCTT TCTGCCCTCT 
CGGGATTACT ACTTAAACAG AACTGCCAAT GAGAAAGTGC TCACTGCCTA TCTGGATTAC 
ATGGAGGAAC TGGGGATGCT GCTGGGTGGG CGGCCCACCT CCACGAGGGA GCAGATGCAG 
CAGGTGCTGG AGTTGGAGAT ACAGCTGGCC AACATCACAG TGCCCCAGGA CCAGCGGCGC 
GACGAGGAGA AGATCTACCA CAAGATGAGC ATTTCGGAGC TGCAGGCTCT GGCGCCCTCC 
ATGGACTGGC TTGAGTTCCT GTCTTTCTTG CTGTCACCAT TGGAGTTGAG TGACTCTGAG 
CCTGTGGTGG TGTATGGGAT GGATTATTTG CAGCAGGTGT CAGAGCTCAT CAACCGCACG 
GAACCAAGCA TCCTGAACAA TTACCTGATC TGGAACCTGG TGCAAAAGAC AACCTCAAGC 
CTGGACCGAC GCTTTGAGTC TGCACAAGAG AAGCTGCTGG AGACCCTCTA TGGCACTAAG 
AAGTCCTGTG TGCCGAGGTG GCAGACCTGC ATCTCCAACA CGGATGACGC CCTTGGCTTT 
GCTTTGGGGT CCCTCTTCGT GAAGGCCACG TTTGACCGGC AAAGCAAAGA AATTGCAGAG 
GGGATGATCA GCGAAATCCG GACCGCATTT GAGGAGGCCC TGGGACAGCT GGTTTGGATG 
GATGAGAAGA CCCGCCAGGC AGCCAAGGAG AAAGCAGATG CCATCTATGA TATGATTGGT 
TTCCCAGACT TTATCCTGGA GCCCAAAGAG CTGGATGATG TTTATGACGG GTACGAAATT 
TCTGAAGATT CTTTCTTCCA AAACATGTTG AATTTGTACA ACTTCTCTGC CAAGGTTATG 
GCTGACCAGC TCCGCAAGCC TCCCAGCCGA GACCAGTGGA GCATGACCCC CCAGACAGTG 
AATGCCTACT ACCTTCCAAC TAAGAATGAG ATCGTCTTCC CCGCTGGCAT CCTGCAGGCC 
CCCTTCTATG CCCGCAACCA CCCCAAGGCC CTGAACTTCG GTGGCATCGG TGTGGTCATG 
GGCCATGAGT TGACGCATGC CTTTGATGAC CAAGGGCGCG AGTATGACAA AGAAGGGAAC 
CTGCGGCCCT GGTGGCAGAA TGAGTCCCTG GCAGCCTTCC GGAACCACAC GGCCTGCATG 
GAGGAACAGT ACAATCAATA CCAGGTCAAT GGGGAGAGGC TCAACGGCCG CCAGACGCTG 
GGGGAGAACA TTGCTGACAA CGGGGGGCTG AAGGCTGCCT ACAATGCTTA CAAAGCATGG 
CTGAGAAAGC ATGGGGAGGA GCAGCAACTG CCAGCCGTGG GGCTCACCAA CCACCAGCTC 
TTCTTCGTGG GATTTGCCCA GGTGTGGTGC TCGGTCCGCA CACCAGAGAG CTCTCACGAG 
GGGCTGGTGA CCGACCCCCA CAGCCCTGCC CGCTTCCGCG TGCTGGGCAC TCTCTCCAAC 
TCCCGTGACT TCCTGCGGCA CTTCGGCTGC CCTGTCGGCT CCCCCATGAA CCCAGGGCAG 
CTGTGTGAGG TGTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ECE2 ( NM_001100121.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093591.1 Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu18010
Clone ID Related Accession (Same CDS sequence)	NM_001100121.1 , NM_001100121.2
Accession Version	NM_001100121.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2298bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	endothelin-converting enzyme 2 isoform E
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC142950.1, AF192531.1, AY359003.1 and AF428263.1. On Jun 2, 2019 this sequence version replaced NM_001100121.1. Transcript Variant: This variant (5) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (E) has a distinct N-terminus compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.12800.1, SRR1803613.60881.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACA TGGTGGAGTA CAAACGGGCC 
ACGCTTCGGG ATGAAGACGC ACCCGAGACC CCCGTAGAGG GCGGGGCCTC CCCGGACGCC 
ATGGAGGTGG GATTCCAGAA GGGGACAAGA CAGCTGTTAG GCTCACGCAC GCAGCTGGAG 
CTGGTCTTAG CAGGTGCCTC TCTACTGCTG GCTGCACTGC TTCTGGGCTG CCTTGTGGCC 
CTAGGGGTCC AGTACCACAG AGACCCATCC CACAGCACCT GCCTTACAGA GGCCTGCATT 
CGAGTGGCTG GAAAAATCCT GGAGTCCCTG GACCGAGGGG TGAGCCCCTG TGAGGACTTT 
TACCAGTTCT CCTGTGGGGG CTGGATTCGG AGGAACCCCC TGCCCGATGG GCGTTCTCGC 
TGGAACACCT TCAACAGCCT CTGGGACCAA AACCAGGCCA TACTGAAGCA CCTGCTTGAA 
AACACCACCT TCAACTCCAG CAGTGAAGCT GAGCAGAAGA CACAGCGCTT CTACCTATCT 
TGCCTACAGG TGGAGCGCAT TGAGGAGCTG GGAGCCCAGC CACTGAGAGA CCTCATTGAG 
AAGATTGGTG GTTGGAACAT TACGGGGCCC TGGGACCAGG ACAACTTTAT GGAGGTGTTG 
AAGGCAGTAG CAGGGACCTA CAGGGCCACC CCATTCTTCA CCGTCTACAT CAGTGCCGAC 
TCTAAGAGTT CCAACAGCAA TGTTATCCAG GTGGACCAGT CTGGGCTCTT TCTGCCCTCT 
CGGGATTACT ACTTAAACAG AACTGCCAAT GAGAAAGTGC TCACTGCCTA TCTGGATTAC 
ATGGAGGAAC TGGGGATGCT GCTGGGTGGG CGGCCCACCT CCACGAGGGA GCAGATGCAG 
CAGGTGCTGG AGTTGGAGAT ACAGCTGGCC AACATCACAG TGCCCCAGGA CCAGCGGCGC 
GACGAGGAGA AGATCTACCA CAAGATGAGC ATTTCGGAGC TGCAGGCTCT GGCGCCCTCC 
ATGGACTGGC TTGAGTTCCT GTCTTTCTTG CTGTCACCAT TGGAGTTGAG TGACTCTGAG 
CCTGTGGTGG TGTATGGGAT GGATTATTTG CAGCAGGTGT CAGAGCTCAT CAACCGCACG 
GAACCAAGCA TCCTGAACAA TTACCTGATC TGGAACCTGG TGCAAAAGAC AACCTCAAGC 
CTGGACCGAC GCTTTGAGTC TGCACAAGAG AAGCTGCTGG AGACCCTCTA TGGCACTAAG 
AAGTCCTGTG TGCCGAGGTG GCAGACCTGC ATCTCCAACA CGGATGACGC CCTTGGCTTT 
GCTTTGGGGT CCCTCTTCGT GAAGGCCACG TTTGACCGGC AAAGCAAAGA AATTGCAGAG 
GGGATGATCA GCGAAATCCG GACCGCATTT GAGGAGGCCC TGGGACAGCT GGTTTGGATG 
GATGAGAAGA CCCGCCAGGC AGCCAAGGAG AAAGCAGATG CCATCTATGA TATGATTGGT 
TTCCCAGACT TTATCCTGGA GCCCAAAGAG CTGGATGATG TTTATGACGG GTACGAAATT 
TCTGAAGATT CTTTCTTCCA AAACATGTTG AATTTGTACA ACTTCTCTGC CAAGGTTATG 
GCTGACCAGC TCCGCAAGCC TCCCAGCCGA GACCAGTGGA GCATGACCCC CCAGACAGTG 
AATGCCTACT ACCTTCCAAC TAAGAATGAG ATCGTCTTCC CCGCTGGCAT CCTGCAGGCC 
CCCTTCTATG CCCGCAACCA CCCCAAGGCC CTGAACTTCG GTGGCATCGG TGTGGTCATG 
GGCCATGAGT TGACGCATGC CTTTGATGAC CAAGGGCGCG AGTATGACAA AGAAGGGAAC 
CTGCGGCCCT GGTGGCAGAA TGAGTCCCTG GCAGCCTTCC GGAACCACAC GGCCTGCATG 
GAGGAACAGT ACAATCAATA CCAGGTCAAT GGGGAGAGGC TCAACGGCCG CCAGACGCTG 
GGGGAGAACA TTGCTGACAA CGGGGGGCTG AAGGCTGCCT ACAATGCTTA CAAAGCATGG 
CTGAGAAAGC ATGGGGAGGA GCAGCAACTG CCAGCCGTGG GGCTCACCAA CCACCAGCTC 
TTCTTCGTGG GATTTGCCCA GGTGTGGTGC TCGGTCCGCA CACCAGAGAG CTCTCACGAG 
GGGCTGGTGA CCGACCCCCA CAGCCCTGCC CGCTTCCGCG TGCTGGGCAC TCTCTCCAAC 
TCCCGTGACT TCCTGCGGCA CTTCGGCTGC CCTGTCGGCT CCCCCATGAA CCCAGGGCAG 
CTGTGTGAGG TGTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093591.1
CDS	133..2430
Translation	MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW

Target ORF information:

RefSeq Version	NM_001100121.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100121.2

ORF Insert Sequence:

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACA TGGTGGAGTA CAAACGGGCC 
ACGCTTCGGG ATGAAGACGC ACCCGAGACC CCCGTAGAGG GCGGGGCCTC CCCGGACGCC 
ATGGAGGTGG GATTCCAGAA GGGGACAAGA CAGCTGTTAG GCTCACGCAC GCAGCTGGAG 
CTGGTCTTAG CAGGTGCCTC TCTACTGCTG GCTGCACTGC TTCTGGGCTG CCTTGTGGCC 
CTAGGGGTCC AGTACCACAG AGACCCATCC CACAGCACCT GCCTTACAGA GGCCTGCATT 
CGAGTGGCTG GAAAAATCCT GGAGTCCCTG GACCGAGGGG TGAGCCCCTG TGAGGACTTT 
TACCAGTTCT CCTGTGGGGG CTGGATTCGG AGGAACCCCC TGCCCGATGG GCGTTCTCGC 
TGGAACACCT TCAACAGCCT CTGGGACCAA AACCAGGCCA TACTGAAGCA CCTGCTTGAA 
AACACCACCT TCAACTCCAG CAGTGAAGCT GAGCAGAAGA CACAGCGCTT CTACCTATCT 
TGCCTACAGG TGGAGCGCAT TGAGGAGCTG GGAGCCCAGC CACTGAGAGA CCTCATTGAG 
AAGATTGGTG GTTGGAACAT TACGGGGCCC TGGGACCAGG ACAACTTTAT GGAGGTGTTG 
AAGGCAGTAG CAGGGACCTA CAGGGCCACC CCATTCTTCA CCGTCTACAT CAGTGCCGAC 
TCTAAGAGTT CCAACAGCAA TGTTATCCAG GTGGACCAGT CTGGGCTCTT TCTGCCCTCT 
CGGGATTACT ACTTAAACAG AACTGCCAAT GAGAAAGTGC TCACTGCCTA TCTGGATTAC 
ATGGAGGAAC TGGGGATGCT GCTGGGTGGG CGGCCCACCT CCACGAGGGA GCAGATGCAG 
CAGGTGCTGG AGTTGGAGAT ACAGCTGGCC AACATCACAG TGCCCCAGGA CCAGCGGCGC 
GACGAGGAGA AGATCTACCA CAAGATGAGC ATTTCGGAGC TGCAGGCTCT GGCGCCCTCC 
ATGGACTGGC TTGAGTTCCT GTCTTTCTTG CTGTCACCAT TGGAGTTGAG TGACTCTGAG 
CCTGTGGTGG TGTATGGGAT GGATTATTTG CAGCAGGTGT CAGAGCTCAT CAACCGCACG 
GAACCAAGCA TCCTGAACAA TTACCTGATC TGGAACCTGG TGCAAAAGAC AACCTCAAGC 
CTGGACCGAC GCTTTGAGTC TGCACAAGAG AAGCTGCTGG AGACCCTCTA TGGCACTAAG 
AAGTCCTGTG TGCCGAGGTG GCAGACCTGC ATCTCCAACA CGGATGACGC CCTTGGCTTT 
GCTTTGGGGT CCCTCTTCGT GAAGGCCACG TTTGACCGGC AAAGCAAAGA AATTGCAGAG 
GGGATGATCA GCGAAATCCG GACCGCATTT GAGGAGGCCC TGGGACAGCT GGTTTGGATG 
GATGAGAAGA CCCGCCAGGC AGCCAAGGAG AAAGCAGATG CCATCTATGA TATGATTGGT 
TTCCCAGACT TTATCCTGGA GCCCAAAGAG CTGGATGATG TTTATGACGG GTACGAAATT 
TCTGAAGATT CTTTCTTCCA AAACATGTTG AATTTGTACA ACTTCTCTGC CAAGGTTATG 
GCTGACCAGC TCCGCAAGCC TCCCAGCCGA GACCAGTGGA GCATGACCCC CCAGACAGTG 
AATGCCTACT ACCTTCCAAC TAAGAATGAG ATCGTCTTCC CCGCTGGCAT CCTGCAGGCC 
CCCTTCTATG CCCGCAACCA CCCCAAGGCC CTGAACTTCG GTGGCATCGG TGTGGTCATG 
GGCCATGAGT TGACGCATGC CTTTGATGAC CAAGGGCGCG AGTATGACAA AGAAGGGAAC 
CTGCGGCCCT GGTGGCAGAA TGAGTCCCTG GCAGCCTTCC GGAACCACAC GGCCTGCATG 
GAGGAACAGT ACAATCAATA CCAGGTCAAT GGGGAGAGGC TCAACGGCCG CCAGACGCTG 
GGGGAGAACA TTGCTGACAA CGGGGGGCTG AAGGCTGCCT ACAATGCTTA CAAAGCATGG 
CTGAGAAAGC ATGGGGAGGA GCAGCAACTG CCAGCCGTGG GGCTCACCAA CCACCAGCTC 
TTCTTCGTGG GATTTGCCCA GGTGTGGTGC TCGGTCCGCA CACCAGAGAG CTCTCACGAG 
GGGCTGGTGA CCGACCCCCA CAGCCCTGCC CGCTTCCGCG TGCTGGGCAC TCTCTCCAAC 
TCCCGTGACT TCCTGCGGCA CTTCGGCTGC CCTGTCGGCT CCCCCATGAA CCCAGGGCAG 
CTGTGTGAGG TGTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ECE2 ( NM_001100120.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093590.1 Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu18608
Clone ID Related Accession (Same CDS sequence)	NM_001100120.1 , NM_001100120.2
Accession Version	NM_001100120.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	endothelin-converting enzyme 2 isoform D
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC142950.1, AF521189.1, AY359003.1 and AF428263.1. Transcript Variant: This variant (4) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (D) has a distinct N-terminus compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.89629.1, SRR1803615.145163.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2151405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACA TGGTGGAGTA CAAACGGGCC 
ACGCTTCGGG ATGAAGACGC ACCCGAGACC CCCGTAGAGG GCGGGGCCTC CCCGGACGCC 
ATGGAGGTGG GCAAGGGGGC TTCCCCTTTC TCACCAGGCC CCAGCCCTGG CATGACGCCT 
GGCACACCCA GGAGCTCTGG GCTGTTCTGG AGGGTCACCT GCCCCCACCT CCGCTCCATC 
TCTGGCCTCT GCTCTAGGAC TATGGTGGGA TTCCAGAAGG GGACAAGACA GCTGTTAGGC 
TCACGCACGC AGCTGGAGCT GGTCTTAGCA GGTGCCTCTC TACTGCTGGC TGCACTGCTT 
CTGGGCTGCC TTGTGGCCCT AGGGGTCCAG TACCACAGAG ACCCATCCCA CAGCACCTGC 
CTTACAGAGG CCTGCATTCG AGTGGCTGGA AAAATCCTGG AGTCCCTGGA CCGAGGGGTG 
AGCCCCTGTG AGGACTTTTA CCAGTTCTCC TGTGGGGGCT GGATTCGGAG GAACCCCCTG 
CCCGATGGGC GTTCTCGCTG GAACACCTTC AACAGCCTCT GGGACCAAAA CCAGGCCATA 
CTGAAGCACC TGCTTGAAAA CACCACCTTC AACTCCAGCA GTGAAGCTGA GCAGAAGACA 
CAGCGCTTCT ACCTATCTTG CCTACAGGTG GAGCGCATTG AGGAGCTGGG AGCCCAGCCA 
CTGAGAGACC TCATTGAGAA GATTGGTGGT TGGAACATTA CGGGGCCCTG GGACCAGGAC 
AACTTTATGG AGGTGTTGAA GGCAGTAGCA GGGACCTACA GGGCCACCCC ATTCTTCACC 
GTCTACATCA GTGCCGACTC TAAGAGTTCC AACAGCAATG TTATCCAGGT GGACCAGTCT 
GGGCTCTTTC TGCCCTCTCG GGATTACTAC TTAAACAGAA CTGCCAATGA GAAAGTGCTC 
ACTGCCTATC TGGATTACAT GGAGGAACTG GGGATGCTGC TGGGTGGGCG GCCCACCTCC 
ACGAGGGAGC AGATGCAGCA GGTGCTGGAG TTGGAGATAC AGCTGGCCAA CATCACAGTG 
CCCCAGGACC AGCGGCGCGA CGAGGAGAAG ATCTACCACA AGATGAGCAT TTCGGAGCTG 
CAGGCTCTGG CGCCCTCCAT GGACTGGCTT GAGTTCCTGT CTTTCTTGCT GTCACCATTG 
GAGTTGAGTG ACTCTGAGCC TGTGGTGGTG TATGGGATGG ATTATTTGCA GCAGGTGTCA 
GAGCTCATCA ACCGCACGGA ACCAAGCATC CTGAACAATT ACCTGATCTG GAACCTGGTG 
CAAAAGACAA CCTCAAGCCT GGACCGACGC TTTGAGTCTG CACAAGAGAA GCTGCTGGAG 
ACCCTCTATG GCACTAAGAA GTCCTGTGTG CCGAGGTGGC AGACCTGCAT CTCCAACACG 
GATGACGCCC TTGGCTTTGC TTTGGGGTCC CTCTTCGTGA AGGCCACGTT TGACCGGCAA 
AGCAAAGAAA TTGCAGAGGG GATGATCAGC GAAATCCGGA CCGCATTTGA GGAGGCCCTG 
GGACAGCTGG TTTGGATGGA TGAGAAGACC CGCCAGGCAG CCAAGGAGAA AGCAGATGCC 
ATCTATGATA TGATTGGTTT CCCAGACTTT ATCCTGGAGC CCAAAGAGCT GGATGATGTT 
TATGACGGGT ACGAAATTTC TGAAGATTCT TTCTTCCAAA ACATGTTGAA TTTGTACAAC 
TTCTCTGCCA AGGTTATGGC TGACCAGCTC CGCAAGCCTC CCAGCCGAGA CCAGTGGAGC 
ATGACCCCCC AGACAGTGAA TGCCTACTAC CTTCCAACTA AGAATGAGAT CGTCTTCCCC 
GCTGGCATCC TGCAGGCCCC CTTCTATGCC CGCAACCACC CCAAGGCCCT GAACTTCGGT 
GGCATCGGTG TGGTCATGGG CCATGAGTTG ACGCATGCCT TTGATGACCA AGGGCGCGAG 
TATGACAAAG AAGGGAACCT GCGGCCCTGG TGGCAGAATG AGTCCCTGGC AGCCTTCCGG 
AACCACACGG CCTGCATGGA GGAACAGTAC AATCAATACC AGGTCAATGG GGAGAGGCTC 
AACGGCCGCC AGACGCTGGG GGAGAACATT GCTGACAACG GGGGGCTGAA GGCTGCCTAC 
AATGCTTACA AAGCATGGCT GAGAAAGCAT GGGGAGGAGC AGCAACTGCC AGCCGTGGGG 
CTCACCAACC ACCAGCTCTT CTTCGTGGGA TTTGCCCAGG TGTGGTGCTC GGTCCGCACA 
CCAGAGAGCT CTCACGAGGG GCTGGTGACC GACCCCCACA GCCCTGCCCG CTTCCGCGTG 
CTGGGCACTC TCTCCAACTC CCGTGACTTC CTGCGGCACT TCGGCTGCCC TGTCGGCTCC 
CCCATGAACC CAGGGCAGCT GTGTGAGGTG TGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093590.1
CDS	144..2579
Translation	MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTPGTPRSSGLFWRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW

Target ORF information:

RefSeq Version	NM_001100120.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100120.1

ORF Insert Sequence:

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACA TGGTGGAGTA CAAACGGGCC 
ACGCTTCGGG ATGAAGACGC ACCCGAGACC CCCGTAGAGG GCGGGGCCTC CCCGGACGCC 
ATGGAGGTGG GCAAGGGGGC TTCCCCTTTC TCACCAGGCC CCAGCCCTGG CATGACGCCT 
GGCACACCCA GGAGCTCTGG GCTGTTCTGG AGGGTCACCT GCCCCCACCT CCGCTCCATC 
TCTGGCCTCT GCTCTAGGAC TATGGTGGGA TTCCAGAAGG GGACAAGACA GCTGTTAGGC 
TCACGCACGC AGCTGGAGCT GGTCTTAGCA GGTGCCTCTC TACTGCTGGC TGCACTGCTT 
CTGGGCTGCC TTGTGGCCCT AGGGGTCCAG TACCACAGAG ACCCATCCCA CAGCACCTGC 
CTTACAGAGG CCTGCATTCG AGTGGCTGGA AAAATCCTGG AGTCCCTGGA CCGAGGGGTG 
AGCCCCTGTG AGGACTTTTA CCAGTTCTCC TGTGGGGGCT GGATTCGGAG GAACCCCCTG 
CCCGATGGGC GTTCTCGCTG GAACACCTTC AACAGCCTCT GGGACCAAAA CCAGGCCATA 
CTGAAGCACC TGCTTGAAAA CACCACCTTC AACTCCAGCA GTGAAGCTGA GCAGAAGACA 
CAGCGCTTCT ACCTATCTTG CCTACAGGTG GAGCGCATTG AGGAGCTGGG AGCCCAGCCA 
CTGAGAGACC TCATTGAGAA GATTGGTGGT TGGAACATTA CGGGGCCCTG GGACCAGGAC 
AACTTTATGG AGGTGTTGAA GGCAGTAGCA GGGACCTACA GGGCCACCCC ATTCTTCACC 
GTCTACATCA GTGCCGACTC TAAGAGTTCC AACAGCAATG TTATCCAGGT GGACCAGTCT 
GGGCTCTTTC TGCCCTCTCG GGATTACTAC TTAAACAGAA CTGCCAATGA GAAAGTGCTC 
ACTGCCTATC TGGATTACAT GGAGGAACTG GGGATGCTGC TGGGTGGGCG GCCCACCTCC 
ACGAGGGAGC AGATGCAGCA GGTGCTGGAG TTGGAGATAC AGCTGGCCAA CATCACAGTG 
CCCCAGGACC AGCGGCGCGA CGAGGAGAAG ATCTACCACA AGATGAGCAT TTCGGAGCTG 
CAGGCTCTGG CGCCCTCCAT GGACTGGCTT GAGTTCCTGT CTTTCTTGCT GTCACCATTG 
GAGTTGAGTG ACTCTGAGCC TGTGGTGGTG TATGGGATGG ATTATTTGCA GCAGGTGTCA 
GAGCTCATCA ACCGCACGGA ACCAAGCATC CTGAACAATT ACCTGATCTG GAACCTGGTG 
CAAAAGACAA CCTCAAGCCT GGACCGACGC TTTGAGTCTG CACAAGAGAA GCTGCTGGAG 
ACCCTCTATG GCACTAAGAA GTCCTGTGTG CCGAGGTGGC AGACCTGCAT CTCCAACACG 
GATGACGCCC TTGGCTTTGC TTTGGGGTCC CTCTTCGTGA AGGCCACGTT TGACCGGCAA 
AGCAAAGAAA TTGCAGAGGG GATGATCAGC GAAATCCGGA CCGCATTTGA GGAGGCCCTG 
GGACAGCTGG TTTGGATGGA TGAGAAGACC CGCCAGGCAG CCAAGGAGAA AGCAGATGCC 
ATCTATGATA TGATTGGTTT CCCAGACTTT ATCCTGGAGC CCAAAGAGCT GGATGATGTT 
TATGACGGGT ACGAAATTTC TGAAGATTCT TTCTTCCAAA ACATGTTGAA TTTGTACAAC 
TTCTCTGCCA AGGTTATGGC TGACCAGCTC CGCAAGCCTC CCAGCCGAGA CCAGTGGAGC 
ATGACCCCCC AGACAGTGAA TGCCTACTAC CTTCCAACTA AGAATGAGAT CGTCTTCCCC 
GCTGGCATCC TGCAGGCCCC CTTCTATGCC CGCAACCACC CCAAGGCCCT GAACTTCGGT 
GGCATCGGTG TGGTCATGGG CCATGAGTTG ACGCATGCCT TTGATGACCA AGGGCGCGAG 
TATGACAAAG AAGGGAACCT GCGGCCCTGG TGGCAGAATG AGTCCCTGGC AGCCTTCCGG 
AACCACACGG CCTGCATGGA GGAACAGTAC AATCAATACC AGGTCAATGG GGAGAGGCTC 
AACGGCCGCC AGACGCTGGG GGAGAACATT GCTGACAACG GGGGGCTGAA GGCTGCCTAC 
AATGCTTACA AAGCATGGCT GAGAAAGCAT GGGGAGGAGC AGCAACTGCC AGCCGTGGGG 
CTCACCAACC ACCAGCTCTT CTTCGTGGGA TTTGCCCAGG TGTGGTGCTC GGTCCGCACA 
CCAGAGAGCT CTCACGAGGG GCTGGTGACC GACCCCCACA GCCCTGCCCG CTTCCGCGTG 
CTGGGCACTC TCTCCAACTC CCGTGACTTC CTGCGGCACT TCGGCTGCCC TGTCGGCTCC 
CCCATGAACC CAGGGCAGCT GTGTGAGGTG TGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ECE2 ( NM_001100120.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093590.1 Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu18608
Clone ID Related Accession (Same CDS sequence)	NM_001100120.1 , NM_001100120.2
Accession Version	NM_001100120.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	endothelin-converting enzyme 2 isoform D
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC142950.1, AF521189.1, AY359003.1 and AF428263.1. On Jun 2, 2019 this sequence version replaced NM_001100120.1. Transcript Variant: This variant (4) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (D) has a distinct N-terminus compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.145163.1, SRR1803612.224415.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2151405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACA TGGTGGAGTA CAAACGGGCC 
ACGCTTCGGG ATGAAGACGC ACCCGAGACC CCCGTAGAGG GCGGGGCCTC CCCGGACGCC 
ATGGAGGTGG GCAAGGGGGC TTCCCCTTTC TCACCAGGCC CCAGCCCTGG CATGACGCCT 
GGCACACCCA GGAGCTCTGG GCTGTTCTGG AGGGTCACCT GCCCCCACCT CCGCTCCATC 
TCTGGCCTCT GCTCTAGGAC TATGGTGGGA TTCCAGAAGG GGACAAGACA GCTGTTAGGC 
TCACGCACGC AGCTGGAGCT GGTCTTAGCA GGTGCCTCTC TACTGCTGGC TGCACTGCTT 
CTGGGCTGCC TTGTGGCCCT AGGGGTCCAG TACCACAGAG ACCCATCCCA CAGCACCTGC 
CTTACAGAGG CCTGCATTCG AGTGGCTGGA AAAATCCTGG AGTCCCTGGA CCGAGGGGTG 
AGCCCCTGTG AGGACTTTTA CCAGTTCTCC TGTGGGGGCT GGATTCGGAG GAACCCCCTG 
CCCGATGGGC GTTCTCGCTG GAACACCTTC AACAGCCTCT GGGACCAAAA CCAGGCCATA 
CTGAAGCACC TGCTTGAAAA CACCACCTTC AACTCCAGCA GTGAAGCTGA GCAGAAGACA 
CAGCGCTTCT ACCTATCTTG CCTACAGGTG GAGCGCATTG AGGAGCTGGG AGCCCAGCCA 
CTGAGAGACC TCATTGAGAA GATTGGTGGT TGGAACATTA CGGGGCCCTG GGACCAGGAC 
AACTTTATGG AGGTGTTGAA GGCAGTAGCA GGGACCTACA GGGCCACCCC ATTCTTCACC 
GTCTACATCA GTGCCGACTC TAAGAGTTCC AACAGCAATG TTATCCAGGT GGACCAGTCT 
GGGCTCTTTC TGCCCTCTCG GGATTACTAC TTAAACAGAA CTGCCAATGA GAAAGTGCTC 
ACTGCCTATC TGGATTACAT GGAGGAACTG GGGATGCTGC TGGGTGGGCG GCCCACCTCC 
ACGAGGGAGC AGATGCAGCA GGTGCTGGAG TTGGAGATAC AGCTGGCCAA CATCACAGTG 
CCCCAGGACC AGCGGCGCGA CGAGGAGAAG ATCTACCACA AGATGAGCAT TTCGGAGCTG 
CAGGCTCTGG CGCCCTCCAT GGACTGGCTT GAGTTCCTGT CTTTCTTGCT GTCACCATTG 
GAGTTGAGTG ACTCTGAGCC TGTGGTGGTG TATGGGATGG ATTATTTGCA GCAGGTGTCA 
GAGCTCATCA ACCGCACGGA ACCAAGCATC CTGAACAATT ACCTGATCTG GAACCTGGTG 
CAAAAGACAA CCTCAAGCCT GGACCGACGC TTTGAGTCTG CACAAGAGAA GCTGCTGGAG 
ACCCTCTATG GCACTAAGAA GTCCTGTGTG CCGAGGTGGC AGACCTGCAT CTCCAACACG 
GATGACGCCC TTGGCTTTGC TTTGGGGTCC CTCTTCGTGA AGGCCACGTT TGACCGGCAA 
AGCAAAGAAA TTGCAGAGGG GATGATCAGC GAAATCCGGA CCGCATTTGA GGAGGCCCTG 
GGACAGCTGG TTTGGATGGA TGAGAAGACC CGCCAGGCAG CCAAGGAGAA AGCAGATGCC 
ATCTATGATA TGATTGGTTT CCCAGACTTT ATCCTGGAGC CCAAAGAGCT GGATGATGTT 
TATGACGGGT ACGAAATTTC TGAAGATTCT TTCTTCCAAA ACATGTTGAA TTTGTACAAC 
TTCTCTGCCA AGGTTATGGC TGACCAGCTC CGCAAGCCTC CCAGCCGAGA CCAGTGGAGC 
ATGACCCCCC AGACAGTGAA TGCCTACTAC CTTCCAACTA AGAATGAGAT CGTCTTCCCC 
GCTGGCATCC TGCAGGCCCC CTTCTATGCC CGCAACCACC CCAAGGCCCT GAACTTCGGT 
GGCATCGGTG TGGTCATGGG CCATGAGTTG ACGCATGCCT TTGATGACCA AGGGCGCGAG 
TATGACAAAG AAGGGAACCT GCGGCCCTGG TGGCAGAATG AGTCCCTGGC AGCCTTCCGG 
AACCACACGG CCTGCATGGA GGAACAGTAC AATCAATACC AGGTCAATGG GGAGAGGCTC 
AACGGCCGCC AGACGCTGGG GGAGAACATT GCTGACAACG GGGGGCTGAA GGCTGCCTAC 
AATGCTTACA AAGCATGGCT GAGAAAGCAT GGGGAGGAGC AGCAACTGCC AGCCGTGGGG 
CTCACCAACC ACCAGCTCTT CTTCGTGGGA TTTGCCCAGG TGTGGTGCTC GGTCCGCACA 
CCAGAGAGCT CTCACGAGGG GCTGGTGACC GACCCCCACA GCCCTGCCCG CTTCCGCGTG 
CTGGGCACTC TCTCCAACTC CCGTGACTTC CTGCGGCACT TCGGCTGCCC TGTCGGCTCC 
CCCATGAACC CAGGGCAGCT GTGTGAGGTG TGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093590.1
CDS	133..2568
Translation	MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTPGTPRSSGLFWRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW

Target ORF information:

RefSeq Version	NM_001100120.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100120.2

ORF Insert Sequence:

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACA TGGTGGAGTA CAAACGGGCC 
ACGCTTCGGG ATGAAGACGC ACCCGAGACC CCCGTAGAGG GCGGGGCCTC CCCGGACGCC 
ATGGAGGTGG GCAAGGGGGC TTCCCCTTTC TCACCAGGCC CCAGCCCTGG CATGACGCCT 
GGCACACCCA GGAGCTCTGG GCTGTTCTGG AGGGTCACCT GCCCCCACCT CCGCTCCATC 
TCTGGCCTCT GCTCTAGGAC TATGGTGGGA TTCCAGAAGG GGACAAGACA GCTGTTAGGC 
TCACGCACGC AGCTGGAGCT GGTCTTAGCA GGTGCCTCTC TACTGCTGGC TGCACTGCTT 
CTGGGCTGCC TTGTGGCCCT AGGGGTCCAG TACCACAGAG ACCCATCCCA CAGCACCTGC 
CTTACAGAGG CCTGCATTCG AGTGGCTGGA AAAATCCTGG AGTCCCTGGA CCGAGGGGTG 
AGCCCCTGTG AGGACTTTTA CCAGTTCTCC TGTGGGGGCT GGATTCGGAG GAACCCCCTG 
CCCGATGGGC GTTCTCGCTG GAACACCTTC AACAGCCTCT GGGACCAAAA CCAGGCCATA 
CTGAAGCACC TGCTTGAAAA CACCACCTTC AACTCCAGCA GTGAAGCTGA GCAGAAGACA 
CAGCGCTTCT ACCTATCTTG CCTACAGGTG GAGCGCATTG AGGAGCTGGG AGCCCAGCCA 
CTGAGAGACC TCATTGAGAA GATTGGTGGT TGGAACATTA CGGGGCCCTG GGACCAGGAC 
AACTTTATGG AGGTGTTGAA GGCAGTAGCA GGGACCTACA GGGCCACCCC ATTCTTCACC 
GTCTACATCA GTGCCGACTC TAAGAGTTCC AACAGCAATG TTATCCAGGT GGACCAGTCT 
GGGCTCTTTC TGCCCTCTCG GGATTACTAC TTAAACAGAA CTGCCAATGA GAAAGTGCTC 
ACTGCCTATC TGGATTACAT GGAGGAACTG GGGATGCTGC TGGGTGGGCG GCCCACCTCC 
ACGAGGGAGC AGATGCAGCA GGTGCTGGAG TTGGAGATAC AGCTGGCCAA CATCACAGTG 
CCCCAGGACC AGCGGCGCGA CGAGGAGAAG ATCTACCACA AGATGAGCAT TTCGGAGCTG 
CAGGCTCTGG CGCCCTCCAT GGACTGGCTT GAGTTCCTGT CTTTCTTGCT GTCACCATTG 
GAGTTGAGTG ACTCTGAGCC TGTGGTGGTG TATGGGATGG ATTATTTGCA GCAGGTGTCA 
GAGCTCATCA ACCGCACGGA ACCAAGCATC CTGAACAATT ACCTGATCTG GAACCTGGTG 
CAAAAGACAA CCTCAAGCCT GGACCGACGC TTTGAGTCTG CACAAGAGAA GCTGCTGGAG 
ACCCTCTATG GCACTAAGAA GTCCTGTGTG CCGAGGTGGC AGACCTGCAT CTCCAACACG 
GATGACGCCC TTGGCTTTGC TTTGGGGTCC CTCTTCGTGA AGGCCACGTT TGACCGGCAA 
AGCAAAGAAA TTGCAGAGGG GATGATCAGC GAAATCCGGA CCGCATTTGA GGAGGCCCTG 
GGACAGCTGG TTTGGATGGA TGAGAAGACC CGCCAGGCAG CCAAGGAGAA AGCAGATGCC 
ATCTATGATA TGATTGGTTT CCCAGACTTT ATCCTGGAGC CCAAAGAGCT GGATGATGTT 
TATGACGGGT ACGAAATTTC TGAAGATTCT TTCTTCCAAA ACATGTTGAA TTTGTACAAC 
TTCTCTGCCA AGGTTATGGC TGACCAGCTC CGCAAGCCTC CCAGCCGAGA CCAGTGGAGC 
ATGACCCCCC AGACAGTGAA TGCCTACTAC CTTCCAACTA AGAATGAGAT CGTCTTCCCC 
GCTGGCATCC TGCAGGCCCC CTTCTATGCC CGCAACCACC CCAAGGCCCT GAACTTCGGT 
GGCATCGGTG TGGTCATGGG CCATGAGTTG ACGCATGCCT TTGATGACCA AGGGCGCGAG 
TATGACAAAG AAGGGAACCT GCGGCCCTGG TGGCAGAATG AGTCCCTGGC AGCCTTCCGG 
AACCACACGG CCTGCATGGA GGAACAGTAC AATCAATACC AGGTCAATGG GGAGAGGCTC 
AACGGCCGCC AGACGCTGGG GGAGAACATT GCTGACAACG GGGGGCTGAA GGCTGCCTAC 
AATGCTTACA AAGCATGGCT GAGAAAGCAT GGGGAGGAGC AGCAACTGCC AGCCGTGGGG 
CTCACCAACC ACCAGCTCTT CTTCGTGGGA TTTGCCCAGG TGTGGTGCTC GGTCCGCACA 
CCAGAGAGCT CTCACGAGGG GCTGGTGACC GACCCCCACA GCCCTGCCCG CTTCCGCGTG 
CTGGGCACTC TCTCCAACTC CCGTGACTTC CTGCGGCACT TCGGCTGCCC TGTCGGCTCC 
CCCATGAACC CAGGGCAGCT GTGTGAGGTG TGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ECE2 ( NM_001037324.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001032401.1 Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu18714
Clone ID Related Accession (Same CDS sequence)	NM_001037324.2 , NM_001037324.3
Accession Version	NM_001037324.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2211bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-22
Organism	Homo sapiens(human)
Product	endothelin-converting enzyme 2 isoform B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC142950.1, AY359003.1 and AF428263.1. On Jul 26, 2007 this sequence version replaced NM_001037324.1. Transcript Variant: This variant (2) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (B) has a distinct N-terminus compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC142950.1, SRR1803617.243814.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACG TGGGATTCCA GAAGGGGACA 
AGACAGCTGT TAGGCTCACG CACGCAGCTG GAGCTGGTCT TAGCAGGTGC CTCTCTACTG 
CTGGCTGCAC TGCTTCTGGG CTGCCTTGTG GCCCTAGGGG TCCAGTACCA CAGAGACCCA 
TCCCACAGCA CCTGCCTTAC AGAGGCCTGC ATTCGAGTGG CTGGAAAAAT CCTGGAGTCC 
CTGGACCGAG GGGTGAGCCC CTGTGAGGAC TTTTACCAGT TCTCCTGTGG GGGCTGGATT 
CGGAGGAACC CCCTGCCCGA TGGGCGTTCT CGCTGGAACA CCTTCAACAG CCTCTGGGAC 
CAAAACCAGG CCATACTGAA GCACCTGCTT GAAAACACCA CCTTCAACTC CAGCAGTGAA 
GCTGAGCAGA AGACACAGCG CTTCTACCTA TCTTGCCTAC AGGTGGAGCG CATTGAGGAG 
CTGGGAGCCC AGCCACTGAG AGACCTCATT GAGAAGATTG GTGGTTGGAA CATTACGGGG 
CCCTGGGACC AGGACAACTT TATGGAGGTG TTGAAGGCAG TAGCAGGGAC CTACAGGGCC 
ACCCCATTCT TCACCGTCTA CATCAGTGCC GACTCTAAGA GTTCCAACAG CAATGTTATC 
CAGGTGGACC AGTCTGGGCT CTTTCTGCCC TCTCGGGATT ACTACTTAAA CAGAACTGCC 
AATGAGAAAG TGCTCACTGC CTATCTGGAT TACATGGAGG AACTGGGGAT GCTGCTGGGT 
GGGCGGCCCA CCTCCACGAG GGAGCAGATG CAGCAGGTGC TGGAGTTGGA GATACAGCTG 
GCCAACATCA CAGTGCCCCA GGACCAGCGG CGCGACGAGG AGAAGATCTA CCACAAGATG 
AGCATTTCGG AGCTGCAGGC TCTGGCGCCC TCCATGGACT GGCTTGAGTT CCTGTCTTTC 
TTGCTGTCAC CATTGGAGTT GAGTGACTCT GAGCCTGTGG TGGTGTATGG GATGGATTAT 
TTGCAGCAGG TGTCAGAGCT CATCAACCGC ACGGAACCAA GCATCCTGAA CAATTACCTG 
ATCTGGAACC TGGTGCAAAA GACAACCTCA AGCCTGGACC GACGCTTTGA GTCTGCACAA 
GAGAAGCTGC TGGAGACCCT CTATGGCACT AAGAAGTCCT GTGTGCCGAG GTGGCAGACC 
TGCATCTCCA ACACGGATGA CGCCCTTGGC TTTGCTTTGG GGTCCCTCTT CGTGAAGGCC 
ACGTTTGACC GGCAAAGCAA AGAAATTGCA GAGGGGATGA TCAGCGAAAT CCGGACCGCA 
TTTGAGGAGG CCCTGGGACA GCTGGTTTGG ATGGATGAGA AGACCCGCCA GGCAGCCAAG 
GAGAAAGCAG ATGCCATCTA TGATATGATT GGTTTCCCAG ACTTTATCCT GGAGCCCAAA 
GAGCTGGATG ATGTTTATGA CGGGTACGAA ATTTCTGAAG ATTCTTTCTT CCAAAACATG 
TTGAATTTGT ACAACTTCTC TGCCAAGGTT ATGGCTGACC AGCTCCGCAA GCCTCCCAGC 
CGAGACCAGT GGAGCATGAC CCCCCAGACA GTGAATGCCT ACTACCTTCC AACTAAGAAT 
GAGATCGTCT TCCCCGCTGG CATCCTGCAG GCCCCCTTCT ATGCCCGCAA CCACCCCAAG 
GCCCTGAACT TCGGTGGCAT CGGTGTGGTC ATGGGCCATG AGTTGACGCA TGCCTTTGAT 
GACCAAGGGC GCGAGTATGA CAAAGAAGGG AACCTGCGGC CCTGGTGGCA GAATGAGTCC 
CTGGCAGCCT TCCGGAACCA CACGGCCTGC ATGGAGGAAC AGTACAATCA ATACCAGGTC 
AATGGGGAGA GGCTCAACGG CCGCCAGACG CTGGGGGAGA ACATTGCTGA CAACGGGGGG 
CTGAAGGCTG CCTACAATGC TTACAAAGCA TGGCTGAGAA AGCATGGGGA GGAGCAGCAA 
CTGCCAGCCG TGGGGCTCAC CAACCACCAG CTCTTCTTCG TGGGATTTGC CCAGGTGTGG 
TGCTCGGTCC GCACACCAGA GAGCTCTCAC GAGGGGCTGG TGACCGACCC CCACAGCCCT 
GCCCGCTTCC GCGTGCTGGG CACTCTCTCC AACTCCCGTG ACTTCCTGCG GCACTTCGGC 
TGCCCTGTCG GCTCCCCCAT GAACCCAGGG CAGCTGTGTG AGGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032401.1
CDS	144..2354
Translation	MNVALQELGAGSNVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW

Target ORF information:

RefSeq Version	NM_001037324.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037324.2

ORF Insert Sequence:

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACG TGGGATTCCA GAAGGGGACA 
AGACAGCTGT TAGGCTCACG CACGCAGCTG GAGCTGGTCT TAGCAGGTGC CTCTCTACTG 
CTGGCTGCAC TGCTTCTGGG CTGCCTTGTG GCCCTAGGGG TCCAGTACCA CAGAGACCCA 
TCCCACAGCA CCTGCCTTAC AGAGGCCTGC ATTCGAGTGG CTGGAAAAAT CCTGGAGTCC 
CTGGACCGAG GGGTGAGCCC CTGTGAGGAC TTTTACCAGT TCTCCTGTGG GGGCTGGATT 
CGGAGGAACC CCCTGCCCGA TGGGCGTTCT CGCTGGAACA CCTTCAACAG CCTCTGGGAC 
CAAAACCAGG CCATACTGAA GCACCTGCTT GAAAACACCA CCTTCAACTC CAGCAGTGAA 
GCTGAGCAGA AGACACAGCG CTTCTACCTA TCTTGCCTAC AGGTGGAGCG CATTGAGGAG 
CTGGGAGCCC AGCCACTGAG AGACCTCATT GAGAAGATTG GTGGTTGGAA CATTACGGGG 
CCCTGGGACC AGGACAACTT TATGGAGGTG TTGAAGGCAG TAGCAGGGAC CTACAGGGCC 
ACCCCATTCT TCACCGTCTA CATCAGTGCC GACTCTAAGA GTTCCAACAG CAATGTTATC 
CAGGTGGACC AGTCTGGGCT CTTTCTGCCC TCTCGGGATT ACTACTTAAA CAGAACTGCC 
AATGAGAAAG TGCTCACTGC CTATCTGGAT TACATGGAGG AACTGGGGAT GCTGCTGGGT 
GGGCGGCCCA CCTCCACGAG GGAGCAGATG CAGCAGGTGC TGGAGTTGGA GATACAGCTG 
GCCAACATCA CAGTGCCCCA GGACCAGCGG CGCGACGAGG AGAAGATCTA CCACAAGATG 
AGCATTTCGG AGCTGCAGGC TCTGGCGCCC TCCATGGACT GGCTTGAGTT CCTGTCTTTC 
TTGCTGTCAC CATTGGAGTT GAGTGACTCT GAGCCTGTGG TGGTGTATGG GATGGATTAT 
TTGCAGCAGG TGTCAGAGCT CATCAACCGC ACGGAACCAA GCATCCTGAA CAATTACCTG 
ATCTGGAACC TGGTGCAAAA GACAACCTCA AGCCTGGACC GACGCTTTGA GTCTGCACAA 
GAGAAGCTGC TGGAGACCCT CTATGGCACT AAGAAGTCCT GTGTGCCGAG GTGGCAGACC 
TGCATCTCCA ACACGGATGA CGCCCTTGGC TTTGCTTTGG GGTCCCTCTT CGTGAAGGCC 
ACGTTTGACC GGCAAAGCAA AGAAATTGCA GAGGGGATGA TCAGCGAAAT CCGGACCGCA 
TTTGAGGAGG CCCTGGGACA GCTGGTTTGG ATGGATGAGA AGACCCGCCA GGCAGCCAAG 
GAGAAAGCAG ATGCCATCTA TGATATGATT GGTTTCCCAG ACTTTATCCT GGAGCCCAAA 
GAGCTGGATG ATGTTTATGA CGGGTACGAA ATTTCTGAAG ATTCTTTCTT CCAAAACATG 
TTGAATTTGT ACAACTTCTC TGCCAAGGTT ATGGCTGACC AGCTCCGCAA GCCTCCCAGC 
CGAGACCAGT GGAGCATGAC CCCCCAGACA GTGAATGCCT ACTACCTTCC AACTAAGAAT 
GAGATCGTCT TCCCCGCTGG CATCCTGCAG GCCCCCTTCT ATGCCCGCAA CCACCCCAAG 
GCCCTGAACT TCGGTGGCAT CGGTGTGGTC ATGGGCCATG AGTTGACGCA TGCCTTTGAT 
GACCAAGGGC GCGAGTATGA CAAAGAAGGG AACCTGCGGC CCTGGTGGCA GAATGAGTCC 
CTGGCAGCCT TCCGGAACCA CACGGCCTGC ATGGAGGAAC AGTACAATCA ATACCAGGTC 
AATGGGGAGA GGCTCAACGG CCGCCAGACG CTGGGGGAGA ACATTGCTGA CAACGGGGGG 
CTGAAGGCTG CCTACAATGC TTACAAAGCA TGGCTGAGAA AGCATGGGGA GGAGCAGCAA 
CTGCCAGCCG TGGGGCTCAC CAACCACCAG CTCTTCTTCG TGGGATTTGC CCAGGTGTGG 
TGCTCGGTCC GCACACCAGA GAGCTCTCAC GAGGGGCTGG TGACCGACCC CCACAGCCCT 
GCCCGCTTCC GCGTGCTGGG CACTCTCTCC AACTCCCGTG ACTTCCTGCG GCACTTCGGC 
TGCCCTGTCG GCTCCCCCAT GAACCCAGGG CAGCTGTGTG AGGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ECE2 ( NM_001037324.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001032401.1 Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu18714
Clone ID Related Accession (Same CDS sequence)	NM_001037324.2 , NM_001037324.3
Accession Version	NM_001037324.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2211bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	endothelin-converting enzyme 2 isoform B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC142950.1, AY359003.1 and AF428263.1. On Jun 2, 2019 this sequence version replaced NM_001037324.2. Transcript Variant: This variant (2) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (B) has a distinct N-terminus compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.243814.1, BC142950.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACG TGGGATTCCA GAAGGGGACA 
AGACAGCTGT TAGGCTCACG CACGCAGCTG GAGCTGGTCT TAGCAGGTGC CTCTCTACTG 
CTGGCTGCAC TGCTTCTGGG CTGCCTTGTG GCCCTAGGGG TCCAGTACCA CAGAGACCCA 
TCCCACAGCA CCTGCCTTAC AGAGGCCTGC ATTCGAGTGG CTGGAAAAAT CCTGGAGTCC 
CTGGACCGAG GGGTGAGCCC CTGTGAGGAC TTTTACCAGT TCTCCTGTGG GGGCTGGATT 
CGGAGGAACC CCCTGCCCGA TGGGCGTTCT CGCTGGAACA CCTTCAACAG CCTCTGGGAC 
CAAAACCAGG CCATACTGAA GCACCTGCTT GAAAACACCA CCTTCAACTC CAGCAGTGAA 
GCTGAGCAGA AGACACAGCG CTTCTACCTA TCTTGCCTAC AGGTGGAGCG CATTGAGGAG 
CTGGGAGCCC AGCCACTGAG AGACCTCATT GAGAAGATTG GTGGTTGGAA CATTACGGGG 
CCCTGGGACC AGGACAACTT TATGGAGGTG TTGAAGGCAG TAGCAGGGAC CTACAGGGCC 
ACCCCATTCT TCACCGTCTA CATCAGTGCC GACTCTAAGA GTTCCAACAG CAATGTTATC 
CAGGTGGACC AGTCTGGGCT CTTTCTGCCC TCTCGGGATT ACTACTTAAA CAGAACTGCC 
AATGAGAAAG TGCTCACTGC CTATCTGGAT TACATGGAGG AACTGGGGAT GCTGCTGGGT 
GGGCGGCCCA CCTCCACGAG GGAGCAGATG CAGCAGGTGC TGGAGTTGGA GATACAGCTG 
GCCAACATCA CAGTGCCCCA GGACCAGCGG CGCGACGAGG AGAAGATCTA CCACAAGATG 
AGCATTTCGG AGCTGCAGGC TCTGGCGCCC TCCATGGACT GGCTTGAGTT CCTGTCTTTC 
TTGCTGTCAC CATTGGAGTT GAGTGACTCT GAGCCTGTGG TGGTGTATGG GATGGATTAT 
TTGCAGCAGG TGTCAGAGCT CATCAACCGC ACGGAACCAA GCATCCTGAA CAATTACCTG 
ATCTGGAACC TGGTGCAAAA GACAACCTCA AGCCTGGACC GACGCTTTGA GTCTGCACAA 
GAGAAGCTGC TGGAGACCCT CTATGGCACT AAGAAGTCCT GTGTGCCGAG GTGGCAGACC 
TGCATCTCCA ACACGGATGA CGCCCTTGGC TTTGCTTTGG GGTCCCTCTT CGTGAAGGCC 
ACGTTTGACC GGCAAAGCAA AGAAATTGCA GAGGGGATGA TCAGCGAAAT CCGGACCGCA 
TTTGAGGAGG CCCTGGGACA GCTGGTTTGG ATGGATGAGA AGACCCGCCA GGCAGCCAAG 
GAGAAAGCAG ATGCCATCTA TGATATGATT GGTTTCCCAG ACTTTATCCT GGAGCCCAAA 
GAGCTGGATG ATGTTTATGA CGGGTACGAA ATTTCTGAAG ATTCTTTCTT CCAAAACATG 
TTGAATTTGT ACAACTTCTC TGCCAAGGTT ATGGCTGACC AGCTCCGCAA GCCTCCCAGC 
CGAGACCAGT GGAGCATGAC CCCCCAGACA GTGAATGCCT ACTACCTTCC AACTAAGAAT 
GAGATCGTCT TCCCCGCTGG CATCCTGCAG GCCCCCTTCT ATGCCCGCAA CCACCCCAAG 
GCCCTGAACT TCGGTGGCAT CGGTGTGGTC ATGGGCCATG AGTTGACGCA TGCCTTTGAT 
GACCAAGGGC GCGAGTATGA CAAAGAAGGG AACCTGCGGC CCTGGTGGCA GAATGAGTCC 
CTGGCAGCCT TCCGGAACCA CACGGCCTGC ATGGAGGAAC AGTACAATCA ATACCAGGTC 
AATGGGGAGA GGCTCAACGG CCGCCAGACG CTGGGGGAGA ACATTGCTGA CAACGGGGGG 
CTGAAGGCTG CCTACAATGC TTACAAAGCA TGGCTGAGAA AGCATGGGGA GGAGCAGCAA 
CTGCCAGCCG TGGGGCTCAC CAACCACCAG CTCTTCTTCG TGGGATTTGC CCAGGTGTGG 
TGCTCGGTCC GCACACCAGA GAGCTCTCAC GAGGGGCTGG TGACCGACCC CCACAGCCCT 
GCCCGCTTCC GCGTGCTGGG CACTCTCTCC AACTCCCGTG ACTTCCTGCG GCACTTCGGC 
TGCCCTGTCG GCTCCCCCAT GAACCCAGGG CAGCTGTGTG AGGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032401.1
CDS	133..2343
Translation	MNVALQELGAGSNVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW

Target ORF information:

RefSeq Version	NM_001037324.3
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037324.3

ORF Insert Sequence:

ATGAACGTCG CGCTGCAGGA GCTGGGAGCT GGCAGCAACG TGGGATTCCA GAAGGGGACA 
AGACAGCTGT TAGGCTCACG CACGCAGCTG GAGCTGGTCT TAGCAGGTGC CTCTCTACTG 
CTGGCTGCAC TGCTTCTGGG CTGCCTTGTG GCCCTAGGGG TCCAGTACCA CAGAGACCCA 
TCCCACAGCA CCTGCCTTAC AGAGGCCTGC ATTCGAGTGG CTGGAAAAAT CCTGGAGTCC 
CTGGACCGAG GGGTGAGCCC CTGTGAGGAC TTTTACCAGT TCTCCTGTGG GGGCTGGATT 
CGGAGGAACC CCCTGCCCGA TGGGCGTTCT CGCTGGAACA CCTTCAACAG CCTCTGGGAC 
CAAAACCAGG CCATACTGAA GCACCTGCTT GAAAACACCA CCTTCAACTC CAGCAGTGAA 
GCTGAGCAGA AGACACAGCG CTTCTACCTA TCTTGCCTAC AGGTGGAGCG CATTGAGGAG 
CTGGGAGCCC AGCCACTGAG AGACCTCATT GAGAAGATTG GTGGTTGGAA CATTACGGGG 
CCCTGGGACC AGGACAACTT TATGGAGGTG TTGAAGGCAG TAGCAGGGAC CTACAGGGCC 
ACCCCATTCT TCACCGTCTA CATCAGTGCC GACTCTAAGA GTTCCAACAG CAATGTTATC 
CAGGTGGACC AGTCTGGGCT CTTTCTGCCC TCTCGGGATT ACTACTTAAA CAGAACTGCC 
AATGAGAAAG TGCTCACTGC CTATCTGGAT TACATGGAGG AACTGGGGAT GCTGCTGGGT 
GGGCGGCCCA CCTCCACGAG GGAGCAGATG CAGCAGGTGC TGGAGTTGGA GATACAGCTG 
GCCAACATCA CAGTGCCCCA GGACCAGCGG CGCGACGAGG AGAAGATCTA CCACAAGATG 
AGCATTTCGG AGCTGCAGGC TCTGGCGCCC TCCATGGACT GGCTTGAGTT CCTGTCTTTC 
TTGCTGTCAC CATTGGAGTT GAGTGACTCT GAGCCTGTGG TGGTGTATGG GATGGATTAT 
TTGCAGCAGG TGTCAGAGCT CATCAACCGC ACGGAACCAA GCATCCTGAA CAATTACCTG 
ATCTGGAACC TGGTGCAAAA GACAACCTCA AGCCTGGACC GACGCTTTGA GTCTGCACAA 
GAGAAGCTGC TGGAGACCCT CTATGGCACT AAGAAGTCCT GTGTGCCGAG GTGGCAGACC 
TGCATCTCCA ACACGGATGA CGCCCTTGGC TTTGCTTTGG GGTCCCTCTT CGTGAAGGCC 
ACGTTTGACC GGCAAAGCAA AGAAATTGCA GAGGGGATGA TCAGCGAAAT CCGGACCGCA 
TTTGAGGAGG CCCTGGGACA GCTGGTTTGG ATGGATGAGA AGACCCGCCA GGCAGCCAAG 
GAGAAAGCAG ATGCCATCTA TGATATGATT GGTTTCCCAG ACTTTATCCT GGAGCCCAAA 
GAGCTGGATG ATGTTTATGA CGGGTACGAA ATTTCTGAAG ATTCTTTCTT CCAAAACATG 
TTGAATTTGT ACAACTTCTC TGCCAAGGTT ATGGCTGACC AGCTCCGCAA GCCTCCCAGC 
CGAGACCAGT GGAGCATGAC CCCCCAGACA GTGAATGCCT ACTACCTTCC AACTAAGAAT 
GAGATCGTCT TCCCCGCTGG CATCCTGCAG GCCCCCTTCT ATGCCCGCAA CCACCCCAAG 
GCCCTGAACT TCGGTGGCAT CGGTGTGGTC ATGGGCCATG AGTTGACGCA TGCCTTTGAT 
GACCAAGGGC GCGAGTATGA CAAAGAAGGG AACCTGCGGC CCTGGTGGCA GAATGAGTCC 
CTGGCAGCCT TCCGGAACCA CACGGCCTGC ATGGAGGAAC AGTACAATCA ATACCAGGTC 
AATGGGGAGA GGCTCAACGG CCGCCAGACG CTGGGGGAGA ACATTGCTGA CAACGGGGGG 
CTGAAGGCTG CCTACAATGC TTACAAAGCA TGGCTGAGAA AGCATGGGGA GGAGCAGCAA 
CTGCCAGCCG TGGGGCTCAC CAACCACCAG CTCTTCTTCG TGGGATTTGC CCAGGTGTGG 
TGCTCGGTCC GCACACCAGA GAGCTCTCAC GAGGGGCTGG TGACCGACCC CCACAGCCCT 
GCCCGCTTCC GCGTGCTGGG CACTCTCTCC AACTCCCGTG ACTTCCTGCG GCACTTCGGC 
TGCCCTGTCG GCTCCCCCAT GAACCCAGGG CAGCTGTGTG AGGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1.
Autoimmunity50(4)223-231(2017 Jun)
Smith-Anttila CJA,Bensing S,Alimohammadi M,Dalin F,Oscarson M,Zhang MD,Perheentupa J,Husebye ES,Gustafsson J,Bj?rklund P,Fransson A,Nordmark G,R?nnblom L,Meloni A,Scott RJ,H?kfelt T,Crock PA,K?mpe O

Endothelin-converting enzymes degrade ?-synuclein and are reduced in dementia with Lewy bodies.
Journal of neurochemistry141(2)275-286(2017 Apr)
Miners JS,Love S

A mega-analysis of genome-wide association studies for major depressive disorder.
Molecular psychiatry18(4)497-511(2013 Apr)
,Ripke S,Wray NR,Lewis CM,Hamilton SP,Weissman MM,Breen G,Byrne EM,Blackwood DH,Boomsma DI,Cichon S,Heath AC,Holsboer F,Lucae S,Madden PA,Martin NG,McGuffin P,Muglia P,Noethen MM,Penninx BP,Pergadia ML,Potash JB,Rietschel M,Lin D,M?ller-Myhsok B,Shi J,Steinberg S,Grabe HJ,Lichtenstein P,Magnusson P,Perlis RH,Preisig M,Smoller JW,Stefansson K,Uher R,Kutalik Z,Tansey KE,Teumer A,Viktorin A,Barnes MR,Bettecken T,Binder EB,Breuer R,Castro VM,Churchill SE,Coryell WH,Craddock N,Craig IW,Czamara D,De Geus EJ,Degenhardt F,Farmer AE,Fava M,Frank J,Gainer VS,Gallagher PJ,Gordon SD,Goryachev S,Gross M,Guipponi M,Henders AK,Herms S,Hickie IB,Hoefels S,Hoogendijk W,Hottenga JJ,Iosifescu DV,Ising M,Jones I,Jones L,Jung-Ying T,Knowles JA,Kohane IS,Kohli MA,Korszun A,Landen M,Lawson WB,Lewis G,Macintyre D,Maier W,Mattheisen M,McGrath PJ,McIntosh A,McLean A,Middeldorp CM,Middleton L,Montgomery GM,Murphy SN,Nauck M,Nolen WA,Nyholt DR,O'Donovan M,Oskarsson H,Pedersen N,Scheftner WA,Schulz A,Schulze TG,Shyn SI,Sigurdsson E,Slager SL,Smit JH,Stefansson H,Steffens M,Thorgeirsson T,Tozzi F,Treutlein J,Uhr M,van den Oord EJ,Van Grootheest G,V?lzke H,Weilburg JB,Willemsen G,Zitman FG,Neale B,Daly M,Levinson DF,Sullivan PF

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American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics159B(6)696-709(2012 Sep)
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Genetic analysis of genes involved in amyloid-? degradation and clearance in Alzheimer's disease.
Journal of Alzheimer's disease : JAD28(3)553-9(2012)
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ECE2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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