IPO13 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IPO13
Entrez Gene ID	9670
Full Name	importin 13
Synonyms	IMP13,KAP13,LGL2,RANBP13
General protein information	Preferred Names importin 13 Names importin-13 Ran binding protein 13 karyopherin 13 late gestation lung 2 ran-binding protein 13
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p34.1
Summary	This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.[provided by RefSeq, Mar 2009].
Disorder MIM:	610411

mRNA and Protein(s)

mRNA	Protein	Name
NM_014652.3	NP_055467.3	importin-13
NM_014652.4	NP_055467.3	importin-13
XM_024451070.1	XP_024306838.1	importin-13 isoform X1
XM_024451069.1	XP_024306837.1	importin-13 isoform X1

Pathways from BioSystems

Homologies

	IPO13	XP_002808259.1
Canis lupus familiaris (dog)	IPO13	XP_532612.2
Bos taurus (cattle)	IPO13	NP_001098860.1
Pan troglodytes (chimpanzee)	IPO13	XP_524696.4
Mus musculus (house mouse)	Ipo13	NP_666264.1
Danio rerio (zebrafish)	ipo13	XP_002665826.2
Xenopus tropicalis (tropical clawed frog)	ipo13	XP_002931629.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009571	XP_318583.4
Drosophila melanogaster (fruit fly)	cdm	NP_650682.1
Homo sapiens (human)	IPO13	NP_055467.3
Rattus norvegicus (Norway rat)	Ipo13	NP_446230.1
Gallus gallus (chicken)	IPO13	NP_001006537.1

Gene Ontology
Bibliography

Related articles in PubMed

Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.
Xie J, Long X, Gao L, Chen S, Zhao K, Li W, Zhou N, Zang N, Deng Y, Ren L, Wang L, Luo Z, Tu W, Zhao X, Fu Z, Xie X, Liu E
The Journal of infectious diseases217(1)35-46(2017 Dec)

Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.
Ansseau E, Eidahl JO, Lancelot C, Tassin A, Matteotti C, Yip C, Liu J, Leroy B, Hubeau C, Gerbaux C, Cloet S, Wauters A, Zorbo S, Meyer P, Pirson I, Laoudj-Chenivesse D, Wattiez R, Harper SQ, Belayew A, Copp?e F
PloS one11(1)e0146893(2016)

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Trigg SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J, Hill DE, Hao T, Vidal M, Iakoucheva LM
Nature communications53650(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IPO13 influenced intracellular distribution of CTCF.
Title: CCCTC-binding factor controls its own nuclear transport via regulating the expression of importin 13.

Imp13 is able to bind and export eIF1A in vivo and that its function is essential.
Title: Structural basis for the nuclear export activity of Importin13.

IPO13 may contribute to the pathogenesis of pterygium via modulation of K17 and c-Jun.
Title: Increased importin 13 activity is associated with the pathogenesis of pterygium.

These results demonstrate an increased expression of IPO13 in endometriosis and endometrial carcinoma.
Title: Increased expression of importin13 in endometriosis and endometrial carcinoma.

Data show that expression of IPO13, c-kit, telomerase, caspase3, and CD146 are decreased in endometrial polyps; however, the expression of bcl-2 was increased in polyps compared to the normal endometrial tissue.
Title: The expression levels of stem cell markers importin13, c-kit, CD146, and telomerase are decreased in endometrial polyps.

The following IPO13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IPO13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11176	NM_014652.4 Latest version!	Homo sapiens importin 13 (IPO13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu63124	XM_024451070.1 Latest version!	Homo sapiens importin 13 (IPO13), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu63124	XM_024451069.1 Latest version!	Homo sapiens importin 13 (IPO13), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu11176	NM_014652.3	Homo sapiens importin 13 (IPO13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IPO13 ( NM_014652.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055467.3 Homo sapiens importin 13 (IPO13), mRNA.

Price & Availability↑

CloneID	OHu11176
Clone ID Related Accession (Same CDS sequence)	NM_014652.3 , NM_014652.4
Accession Version	NM_014652.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	importin-13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL357079.24, AB018267.1 and BX116797.1. On or before Aug 3, 2011 this sequence version replaced XM_003403720.1, NM_014652.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB018267.1, SRR1803615.249357.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGGC GGGAGGAGCA GCCGGGGGCT GCAGGGGCTG GAGCAGCACC AGCCTTGGAC 
TTCACTGTGG AGAACGTGGA GAAGGCGCTG CACCAGCTCT ACTATGATCC CAACATTGAG 
AATAAGAACC TGGCTCAGAA GTGGCTGATG CAGGCCCAGG TCTCCCCACA GGCCTGGCAC 
TTCAGCTGGC AGCTACTGCA GCCCGACAAG GTACCAGAGA TCCAGTACTT TGGGGCCAGT 
GCTCTTCACA TCAAGATCTC TCGCTACTGG AGTGACATCC CCACTGACCA GTATGAAAGC 
CTAAAGGCAC AGCTCTTCAC CCAGATCACC CGCTTTGCCA GTGGCTCCAA GATTGTACTG 
ACTCGGCTGT GCGTGGCACT GGCCTCACTG GCTCTCAGCA TGATGCCTGA CGCTTGGCCA 
TGTGCTGTGG CAGATATGGT ACGACTCTTC CAGGCTGAGG ACTCACCAGT GGATGGGCAG 
GGCCGCTGCC TAGCCCTGTT AGAGCTGCTG ACAGTGCTGC CTGAGGAGTT CCAGACCAGT 
CGCCTACCCC AGTACCGCAA AGGCCTGGTG CGGACCAGCC TGGCGGTGGA ATGTGGGGCT 
GTCTTCCCGC TGCTGGAGCA GCTGCTACAG CAGCCCAGCT CACCCAGCTG TGTGCGTCAG 
AAGGTGCTCA AGTGTTTCTC CAGCTGGGTG CAGCTGGAGG TGCCGCTGCA GGACTGTGAG 
GCGCTCATTC AGGCTGCCTT TGCTGCTCTG CAGGACTCGG AGCTCTTCGA CAGCAGTGTG 
GAGGCCATTG TGAATGCCAT CTCACAGCCT GATGCCCAGA GGTACGTGAA CACACTCCTG 
AAACTCATCC CGCTGGTGCT GGGTCTGCAG GAACAACTGC GGCAGGCAGT GCAGAATGGG 
GACATGGAGA CCTCCCATGG CATCTGTCGC ATCGCTGTGG CCCTGGGCGA GAACCACTCC 
CGGGCCTTGC TGGACCAAGT AGAGCACTGG CAGAGTTTCC TGGCACTCGT CAACATGATT 
ATGTTCTGCA CAGGCATCCC TGGCCACTAT CCTGTCAATG AGACCACCAG CTCCCTAACC 
CTCACCTTCT GGTACACACT GCAGGATGAT ATTCTATCCT TTGAGGCAGA GAAGCAGGCT 
GTATACCAGC AGGTGTACCG GCCAGTCTAC TTCCAGCTGG TGGATGTGCT TCTGCACAAG 
GCCCAGTTCC CTTCTGATGA GGAATATGGA TTCTGGTCCT CAGACGAGAA GGAGCAGTTC 
CGAATTTACA GGGTGGACAT CTCAGACACG CTCATGTATG TCTATGAGAT GTTGGGGGCC 
GAGCTGCTCA GCAACCTCTA TGACAAGCTG GGTCGTTTGC TCACCAGCTC AGAGGAGCCC 
TACTCCTGGC AGCACACAGA GGCCCTCCTC TACGGCTTCC AATCCATCGC AGAGACCATT 
GACGTCAACT ATTCTGATGT GGTGCCTGGG CTCATTGGCC TCATCCCACG GATCAGCATC 
AGCAACGTGC AGCTGGCAGA CACTGTCATG TTCACCATTG GAGCTCTGTC TGAATGGCTG 
GCTGACCACC CCGTCATGAT CAACAGTGTT CTGCCCTTGG TACTGCATGC CCTAGGCAAT 
CCTGAGCTGT CTGTCTCTTC TGTGTCCACC CTCAAGAAGA TCTGCCGAGA GTGCAAGTAT 
GACCTGCCTC CCTATGCTGC CAACATTGTG GCTGTGTCCC AGGATGTGCT GATGAAACAG 
ATCCACAAGA CAAGCCAGTG CATGTGGCTG ATGCAGGCGC TGGGCTTCCT GCTGTCAGCT 
CTTCAAGTGG AGGAGATCCT TAAGAACCTG CACTCGCTTA TCTCACCCTA TATCCAGCAA 
CTGGAGAAGC TGGCAGAGGA GATACCCAAT CCCTCCAACA AGCTGGCCAT TGTTCACATC 
TTGGGGCTTC TCTCCAACCT CTTCACCACA CTGGACATCA GTCATCATGA GGATGATCAT 
GAAGGCCCTG AGCTTCGGAA GCTGCCAGTG CCACAGGGAC CCAACCCCGT GGTGGTGGTG 
CTGCAGCAGG TCTTCCAGCT TATCCAGAAG GTGCTGAGCA AATGGTTGAA TGATGCCCAG 
GTTGTGGAGG CGGTGTGCGC TATCTTTGAG AAGTCTGTTA AGACGCTGCT GGATGACTTT 
GCCCCCATGG TGCCACAGCT GTGTGAGATG CTGGGTCGGA TGTACAGCAC CATCCCCCAG 
GCCTCTGCTC TTGACCTCAC TCGACAGCTG GTCCACATCT TTGCTCATGA GCCTGCCCAC 
TTTCCCCCAA TTGAGGCCCT CTTCCTGCTC GTCACCTCCG TCACACTCAC TCTCTTCCAG 
CAAGGGCCCA GGGATCATCC TGATATTGTT GATTCATTTA TGCAACTCCT GGCACAGGCT 
CTGAAGCGGA AGCCAGATTT GTTCCTGTGT GAACGATTGG ATGTCAAAGC TGTGTTCCAG 
TGTGCTGTGC TGGCCCTCAA GTTCCCTGAG GCACCTACTG TCAAGGCCTC CTGTGGCTTC 
TTTACAGAGC TGCTGCCTCG GTGTGGGGAA GTAGAGTCTG TGGGAAAGGT GGTACAGGAA 
GACGGTCGTA TGCTGCTCAT AGCAGTGCTG GAGGCCATTG GGGGCCAGGC CTCCCGCAGC 
CTCATGGACT GCTTTGCCGA TATCCTGTTC GCCCTGAACA AGCACTGCTT CAGCCTCCTG 
AGCATGTGGA TCAAGGAGGC CCTGCAGCCA CCTGGTTTCC CCTCTGCCCG CCTCAGCCCT 
GAACAGAAGG ATACCTTCAG CCAGCAGATC CTTCGCGAGC GAGTGAACAA GAGGCGGGTG 
AAGGAGATGG TGAAGGAGTT CACACTGCTG TGCCGGGGTC TCCATGGCAC AGATTACACA 
GCTGACTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055467.3
CDS	796..3687
Translation	MERREEQPGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTSRLPQYRKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCEALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDHEGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDFAPMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGFFTELLPRCGEVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLLSMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYTADY

Target ORF information:

RefSeq Version	NM_014652.3
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 13 (IPO13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014652.3

ORF Insert Sequence:

ATGGAGCGGC GGGAGGAGCA GCCGGGGGCT GCAGGGGCTG GAGCAGCACC AGCCTTGGAC 
TTCACTGTGG AGAACGTGGA GAAGGCGCTG CACCAGCTCT ACTATGATCC CAACATTGAG 
AATAAGAACC TGGCTCAGAA GTGGCTGATG CAGGCCCAGG TCTCCCCACA GGCCTGGCAC 
TTCAGCTGGC AGCTACTGCA GCCCGACAAG GTACCAGAGA TCCAGTACTT TGGGGCCAGT 
GCTCTTCACA TCAAGATCTC TCGCTACTGG AGTGACATCC CCACTGACCA GTATGAAAGC 
CTAAAGGCAC AGCTCTTCAC CCAGATCACC CGCTTTGCCA GTGGCTCCAA GATTGTACTG 
ACTCGGCTGT GCGTGGCACT GGCCTCACTG GCTCTCAGCA TGATGCCTGA CGCTTGGCCA 
TGTGCTGTGG CAGATATGGT ACGACTCTTC CAGGCTGAGG ACTCACCAGT GGATGGGCAG 
GGCCGCTGCC TAGCCCTGTT AGAGCTGCTG ACAGTGCTGC CTGAGGAGTT CCAGACCAGT 
CGCCTACCCC AGTACCGCAA AGGCCTGGTG CGGACCAGCC TGGCGGTGGA ATGTGGGGCT 
GTCTTCCCGC TGCTGGAGCA GCTGCTACAG CAGCCCAGCT CACCCAGCTG TGTGCGTCAG 
AAGGTGCTCA AGTGTTTCTC CAGCTGGGTG CAGCTGGAGG TGCCGCTGCA GGACTGTGAG 
GCGCTCATTC AGGCTGCCTT TGCTGCTCTG CAGGACTCGG AGCTCTTCGA CAGCAGTGTG 
GAGGCCATTG TGAATGCCAT CTCACAGCCT GATGCCCAGA GGTACGTGAA CACACTCCTG 
AAACTCATCC CGCTGGTGCT GGGTCTGCAG GAACAACTGC GGCAGGCAGT GCAGAATGGG 
GACATGGAGA CCTCCCATGG CATCTGTCGC ATCGCTGTGG CCCTGGGCGA GAACCACTCC 
CGGGCCTTGC TGGACCAAGT AGAGCACTGG CAGAGTTTCC TGGCACTCGT CAACATGATT 
ATGTTCTGCA CAGGCATCCC TGGCCACTAT CCTGTCAATG AGACCACCAG CTCCCTAACC 
CTCACCTTCT GGTACACACT GCAGGATGAT ATTCTATCCT TTGAGGCAGA GAAGCAGGCT 
GTATACCAGC AGGTGTACCG GCCAGTCTAC TTCCAGCTGG TGGATGTGCT TCTGCACAAG 
GCCCAGTTCC CTTCTGATGA GGAATATGGA TTCTGGTCCT CAGACGAGAA GGAGCAGTTC 
CGAATTTACA GGGTGGACAT CTCAGACACG CTCATGTATG TCTATGAGAT GTTGGGGGCC 
GAGCTGCTCA GCAACCTCTA TGACAAGCTG GGTCGTTTGC TCACCAGCTC AGAGGAGCCC 
TACTCCTGGC AGCACACAGA GGCCCTCCTC TACGGCTTCC AATCCATCGC AGAGACCATT 
GACGTCAACT ATTCTGATGT GGTGCCTGGG CTCATTGGCC TCATCCCACG GATCAGCATC 
AGCAACGTGC AGCTGGCAGA CACTGTCATG TTCACCATTG GAGCTCTGTC TGAATGGCTG 
GCTGACCACC CCGTCATGAT CAACAGTGTT CTGCCCTTGG TACTGCATGC CCTAGGCAAT 
CCTGAGCTGT CTGTCTCTTC TGTGTCCACC CTCAAGAAGA TCTGCCGAGA GTGCAAGTAT 
GACCTGCCTC CCTATGCTGC CAACATTGTG GCTGTGTCCC AGGATGTGCT GATGAAACAG 
ATCCACAAGA CAAGCCAGTG CATGTGGCTG ATGCAGGCGC TGGGCTTCCT GCTGTCAGCT 
CTTCAAGTGG AGGAGATCCT TAAGAACCTG CACTCGCTTA TCTCACCCTA TATCCAGCAA 
CTGGAGAAGC TGGCAGAGGA GATACCCAAT CCCTCCAACA AGCTGGCCAT TGTTCACATC 
TTGGGGCTTC TCTCCAACCT CTTCACCACA CTGGACATCA GTCATCATGA GGATGATCAT 
GAAGGCCCTG AGCTTCGGAA GCTGCCAGTG CCACAGGGAC CCAACCCCGT GGTGGTGGTG 
CTGCAGCAGG TCTTCCAGCT TATCCAGAAG GTGCTGAGCA AATGGTTGAA TGATGCCCAG 
GTTGTGGAGG CGGTGTGCGC TATCTTTGAG AAGTCTGTTA AGACGCTGCT GGATGACTTT 
GCCCCCATGG TGCCACAGCT GTGTGAGATG CTGGGTCGGA TGTACAGCAC CATCCCCCAG 
GCCTCTGCTC TTGACCTCAC TCGACAGCTG GTCCACATCT TTGCTCATGA GCCTGCCCAC 
TTTCCCCCAA TTGAGGCCCT CTTCCTGCTC GTCACCTCCG TCACACTCAC TCTCTTCCAG 
CAAGGGCCCA GGGATCATCC TGATATTGTT GATTCATTTA TGCAACTCCT GGCACAGGCT 
CTGAAGCGGA AGCCAGATTT GTTCCTGTGT GAACGATTGG ATGTCAAAGC TGTGTTCCAG 
TGTGCTGTGC TGGCCCTCAA GTTCCCTGAG GCACCTACTG TCAAGGCCTC CTGTGGCTTC 
TTTACAGAGC TGCTGCCTCG GTGTGGGGAA GTAGAGTCTG TGGGAAAGGT GGTACAGGAA 
GACGGTCGTA TGCTGCTCAT AGCAGTGCTG GAGGCCATTG GGGGCCAGGC CTCCCGCAGC 
CTCATGGACT GCTTTGCCGA TATCCTGTTC GCCCTGAACA AGCACTGCTT CAGCCTCCTG 
AGCATGTGGA TCAAGGAGGC CCTGCAGCCA CCTGGTTTCC CCTCTGCCCG CCTCAGCCCT 
GAACAGAAGG ATACCTTCAG CCAGCAGATC CTTCGCGAGC GAGTGAACAA GAGGCGGGTG 
AAGGAGATGG TGAAGGAGTT CACACTGCTG TGCCGGGGTC TCCATGGCAC AGATTACACA 
GCTGACTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO13 ( NM_014652.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055467.3 Homo sapiens importin 13 (IPO13), mRNA.

Price & Availability↑

CloneID	OHu11176
Clone ID Related Accession (Same CDS sequence)	NM_014652.3 , NM_014652.4
Accession Version	NM_014652.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	importin-13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB018267.1, AL357079.24 and BX116797.1. On Nov 22, 2018 this sequence version replaced NM_014652.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB018267.1, SRR1803615.249357.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372343.8/ ENSP00000361418.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCGGC GGGAGGAGCA GCCGGGGGCT GCAGGGGCTG GAGCAGCACC AGCCTTGGAC 
TTCACTGTGG AGAACGTGGA GAAGGCGCTG CACCAGCTCT ACTATGATCC CAACATTGAG 
AATAAGAACC TGGCTCAGAA GTGGCTGATG CAGGCCCAGG TCTCCCCACA GGCCTGGCAC 
TTCAGCTGGC AGCTACTGCA GCCCGACAAG GTACCAGAGA TCCAGTACTT TGGGGCCAGT 
GCTCTTCACA TCAAGATCTC TCGCTACTGG AGTGACATCC CCACTGACCA GTATGAAAGC 
CTAAAGGCAC AGCTCTTCAC CCAGATCACC CGCTTTGCCA GTGGCTCCAA GATTGTACTG 
ACTCGGCTGT GCGTGGCACT GGCCTCACTG GCTCTCAGCA TGATGCCTGA CGCTTGGCCA 
TGTGCTGTGG CAGATATGGT ACGACTCTTC CAGGCTGAGG ACTCACCAGT GGATGGGCAG 
GGCCGCTGCC TAGCCCTGTT AGAGCTGCTG ACAGTGCTGC CTGAGGAGTT CCAGACCAGT 
CGCCTACCCC AGTACCGCAA AGGCCTGGTG CGGACCAGCC TGGCGGTGGA ATGTGGGGCT 
GTCTTCCCGC TGCTGGAGCA GCTGCTACAG CAGCCCAGCT CACCCAGCTG TGTGCGTCAG 
AAGGTGCTCA AGTGTTTCTC CAGCTGGGTG CAGCTGGAGG TGCCGCTGCA GGACTGTGAG 
GCGCTCATTC AGGCTGCCTT TGCTGCTCTG CAGGACTCGG AGCTCTTCGA CAGCAGTGTG 
GAGGCCATTG TGAATGCCAT CTCACAGCCT GATGCCCAGA GGTACGTGAA CACACTCCTG 
AAACTCATCC CGCTGGTGCT GGGTCTGCAG GAACAACTGC GGCAGGCAGT GCAGAATGGG 
GACATGGAGA CCTCCCATGG CATCTGTCGC ATCGCTGTGG CCCTGGGCGA GAACCACTCC 
CGGGCCTTGC TGGACCAAGT AGAGCACTGG CAGAGTTTCC TGGCACTCGT CAACATGATT 
ATGTTCTGCA CAGGCATCCC TGGCCACTAT CCTGTCAATG AGACCACCAG CTCCCTAACC 
CTCACCTTCT GGTACACACT GCAGGATGAT ATTCTATCCT TTGAGGCAGA GAAGCAGGCT 
GTATACCAGC AGGTGTACCG GCCAGTCTAC TTCCAGCTGG TGGATGTGCT TCTGCACAAG 
GCCCAGTTCC CTTCTGATGA GGAATATGGA TTCTGGTCCT CAGACGAGAA GGAGCAGTTC 
CGAATTTACA GGGTGGACAT CTCAGACACG CTCATGTATG TCTATGAGAT GTTGGGGGCC 
GAGCTGCTCA GCAACCTCTA TGACAAGCTG GGTCGTTTGC TCACCAGCTC AGAGGAGCCC 
TACTCCTGGC AGCACACAGA GGCCCTCCTC TACGGCTTCC AATCCATCGC AGAGACCATT 
GACGTCAACT ATTCTGATGT GGTGCCTGGG CTCATTGGCC TCATCCCACG GATCAGCATC 
AGCAACGTGC AGCTGGCAGA CACTGTCATG TTCACCATTG GAGCTCTGTC TGAATGGCTG 
GCTGACCACC CCGTCATGAT CAACAGTGTT CTGCCCTTGG TACTGCATGC CCTAGGCAAT 
CCTGAGCTGT CTGTCTCTTC TGTGTCCACC CTCAAGAAGA TCTGCCGAGA GTGCAAGTAT 
GACCTGCCTC CCTATGCTGC CAACATTGTG GCTGTGTCCC AGGATGTGCT GATGAAACAG 
ATCCACAAGA CAAGCCAGTG CATGTGGCTG ATGCAGGCGC TGGGCTTCCT GCTGTCAGCT 
CTTCAAGTGG AGGAGATCCT TAAGAACCTG CACTCGCTTA TCTCACCCTA TATCCAGCAA 
CTGGAGAAGC TGGCAGAGGA GATACCCAAT CCCTCCAACA AGCTGGCCAT TGTTCACATC 
TTGGGGCTTC TCTCCAACCT CTTCACCACA CTGGACATCA GTCATCATGA GGATGATCAT 
GAAGGCCCTG AGCTTCGGAA GCTGCCAGTG CCACAGGGAC CCAACCCCGT GGTGGTGGTG 
CTGCAGCAGG TCTTCCAGCT TATCCAGAAG GTGCTGAGCA AATGGTTGAA TGATGCCCAG 
GTTGTGGAGG CGGTGTGCGC TATCTTTGAG AAGTCTGTTA AGACGCTGCT GGATGACTTT 
GCCCCCATGG TGCCACAGCT GTGTGAGATG CTGGGTCGGA TGTACAGCAC CATCCCCCAG 
GCCTCTGCTC TTGACCTCAC TCGACAGCTG GTCCACATCT TTGCTCATGA GCCTGCCCAC 
TTTCCCCCAA TTGAGGCCCT CTTCCTGCTC GTCACCTCCG TCACACTCAC TCTCTTCCAG 
CAAGGGCCCA GGGATCATCC TGATATTGTT GATTCATTTA TGCAACTCCT GGCACAGGCT 
CTGAAGCGGA AGCCAGATTT GTTCCTGTGT GAACGATTGG ATGTCAAAGC TGTGTTCCAG 
TGTGCTGTGC TGGCCCTCAA GTTCCCTGAG GCACCTACTG TCAAGGCCTC CTGTGGCTTC 
TTTACAGAGC TGCTGCCTCG GTGTGGGGAA GTAGAGTCTG TGGGAAAGGT GGTACAGGAA 
GACGGTCGTA TGCTGCTCAT AGCAGTGCTG GAGGCCATTG GGGGCCAGGC CTCCCGCAGC 
CTCATGGACT GCTTTGCCGA TATCCTGTTC GCCCTGAACA AGCACTGCTT CAGCCTCCTG 
AGCATGTGGA TCAAGGAGGC CCTGCAGCCA CCTGGTTTCC CCTCTGCCCG CCTCAGCCCT 
GAACAGAAGG ATACCTTCAG CCAGCAGATC CTTCGCGAGC GAGTGAACAA GAGGCGGGTG 
AAGGAGATGG TGAAGGAGTT CACACTGCTG TGCCGGGGTC TCCATGGCAC AGATTACACA 
GCTGACTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055467.3
CDS	652..3543
Translation	MERREEQPGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTSRLPQYRKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCEALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDHEGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDFAPMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGFFTELLPRCGEVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLLSMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYTADY

Target ORF information:

RefSeq Version	NM_014652.4
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 13 (IPO13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014652.4

ORF Insert Sequence:

ATGGAGCGGC GGGAGGAGCA GCCGGGGGCT GCAGGGGCTG GAGCAGCACC AGCCTTGGAC 
TTCACTGTGG AGAACGTGGA GAAGGCGCTG CACCAGCTCT ACTATGATCC CAACATTGAG 
AATAAGAACC TGGCTCAGAA GTGGCTGATG CAGGCCCAGG TCTCCCCACA GGCCTGGCAC 
TTCAGCTGGC AGCTACTGCA GCCCGACAAG GTACCAGAGA TCCAGTACTT TGGGGCCAGT 
GCTCTTCACA TCAAGATCTC TCGCTACTGG AGTGACATCC CCACTGACCA GTATGAAAGC 
CTAAAGGCAC AGCTCTTCAC CCAGATCACC CGCTTTGCCA GTGGCTCCAA GATTGTACTG 
ACTCGGCTGT GCGTGGCACT GGCCTCACTG GCTCTCAGCA TGATGCCTGA CGCTTGGCCA 
TGTGCTGTGG CAGATATGGT ACGACTCTTC CAGGCTGAGG ACTCACCAGT GGATGGGCAG 
GGCCGCTGCC TAGCCCTGTT AGAGCTGCTG ACAGTGCTGC CTGAGGAGTT CCAGACCAGT 
CGCCTACCCC AGTACCGCAA AGGCCTGGTG CGGACCAGCC TGGCGGTGGA ATGTGGGGCT 
GTCTTCCCGC TGCTGGAGCA GCTGCTACAG CAGCCCAGCT CACCCAGCTG TGTGCGTCAG 
AAGGTGCTCA AGTGTTTCTC CAGCTGGGTG CAGCTGGAGG TGCCGCTGCA GGACTGTGAG 
GCGCTCATTC AGGCTGCCTT TGCTGCTCTG CAGGACTCGG AGCTCTTCGA CAGCAGTGTG 
GAGGCCATTG TGAATGCCAT CTCACAGCCT GATGCCCAGA GGTACGTGAA CACACTCCTG 
AAACTCATCC CGCTGGTGCT GGGTCTGCAG GAACAACTGC GGCAGGCAGT GCAGAATGGG 
GACATGGAGA CCTCCCATGG CATCTGTCGC ATCGCTGTGG CCCTGGGCGA GAACCACTCC 
CGGGCCTTGC TGGACCAAGT AGAGCACTGG CAGAGTTTCC TGGCACTCGT CAACATGATT 
ATGTTCTGCA CAGGCATCCC TGGCCACTAT CCTGTCAATG AGACCACCAG CTCCCTAACC 
CTCACCTTCT GGTACACACT GCAGGATGAT ATTCTATCCT TTGAGGCAGA GAAGCAGGCT 
GTATACCAGC AGGTGTACCG GCCAGTCTAC TTCCAGCTGG TGGATGTGCT TCTGCACAAG 
GCCCAGTTCC CTTCTGATGA GGAATATGGA TTCTGGTCCT CAGACGAGAA GGAGCAGTTC 
CGAATTTACA GGGTGGACAT CTCAGACACG CTCATGTATG TCTATGAGAT GTTGGGGGCC 
GAGCTGCTCA GCAACCTCTA TGACAAGCTG GGTCGTTTGC TCACCAGCTC AGAGGAGCCC 
TACTCCTGGC AGCACACAGA GGCCCTCCTC TACGGCTTCC AATCCATCGC AGAGACCATT 
GACGTCAACT ATTCTGATGT GGTGCCTGGG CTCATTGGCC TCATCCCACG GATCAGCATC 
AGCAACGTGC AGCTGGCAGA CACTGTCATG TTCACCATTG GAGCTCTGTC TGAATGGCTG 
GCTGACCACC CCGTCATGAT CAACAGTGTT CTGCCCTTGG TACTGCATGC CCTAGGCAAT 
CCTGAGCTGT CTGTCTCTTC TGTGTCCACC CTCAAGAAGA TCTGCCGAGA GTGCAAGTAT 
GACCTGCCTC CCTATGCTGC CAACATTGTG GCTGTGTCCC AGGATGTGCT GATGAAACAG 
ATCCACAAGA CAAGCCAGTG CATGTGGCTG ATGCAGGCGC TGGGCTTCCT GCTGTCAGCT 
CTTCAAGTGG AGGAGATCCT TAAGAACCTG CACTCGCTTA TCTCACCCTA TATCCAGCAA 
CTGGAGAAGC TGGCAGAGGA GATACCCAAT CCCTCCAACA AGCTGGCCAT TGTTCACATC 
TTGGGGCTTC TCTCCAACCT CTTCACCACA CTGGACATCA GTCATCATGA GGATGATCAT 
GAAGGCCCTG AGCTTCGGAA GCTGCCAGTG CCACAGGGAC CCAACCCCGT GGTGGTGGTG 
CTGCAGCAGG TCTTCCAGCT TATCCAGAAG GTGCTGAGCA AATGGTTGAA TGATGCCCAG 
GTTGTGGAGG CGGTGTGCGC TATCTTTGAG AAGTCTGTTA AGACGCTGCT GGATGACTTT 
GCCCCCATGG TGCCACAGCT GTGTGAGATG CTGGGTCGGA TGTACAGCAC CATCCCCCAG 
GCCTCTGCTC TTGACCTCAC TCGACAGCTG GTCCACATCT TTGCTCATGA GCCTGCCCAC 
TTTCCCCCAA TTGAGGCCCT CTTCCTGCTC GTCACCTCCG TCACACTCAC TCTCTTCCAG 
CAAGGGCCCA GGGATCATCC TGATATTGTT GATTCATTTA TGCAACTCCT GGCACAGGCT 
CTGAAGCGGA AGCCAGATTT GTTCCTGTGT GAACGATTGG ATGTCAAAGC TGTGTTCCAG 
TGTGCTGTGC TGGCCCTCAA GTTCCCTGAG GCACCTACTG TCAAGGCCTC CTGTGGCTTC 
TTTACAGAGC TGCTGCCTCG GTGTGGGGAA GTAGAGTCTG TGGGAAAGGT GGTACAGGAA 
GACGGTCGTA TGCTGCTCAT AGCAGTGCTG GAGGCCATTG GGGGCCAGGC CTCCCGCAGC 
CTCATGGACT GCTTTGCCGA TATCCTGTTC GCCCTGAACA AGCACTGCTT CAGCCTCCTG 
AGCATGTGGA TCAAGGAGGC CCTGCAGCCA CCTGGTTTCC CCTCTGCCCG CCTCAGCCCT 
GAACAGAAGG ATACCTTCAG CCAGCAGATC CTTCGCGAGC GAGTGAACAA GAGGCGGGTG 
AAGGAGATGG TGAAGGAGTT CACACTGCTG TGCCGGGGTC TCCATGGCAC AGATTACACA 
GCTGACTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO13 ( XM_024451070.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306838.1 Homo sapiens importin 13 (IPO13), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu63124
Clone ID Related Accession (Same CDS sequence)	XM_024451070.1 , XM_024451069.1
Accession Version	XM_024451070.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1989bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	importin-13 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGACCT CCCATGGCAT CTGTCGCATC GCTGTGGCCC TGGGCGAGAA CCACTCCCGG 
GCCTTGCTGG ACCAAGTAGA GCACTGGCAG AGTTTCCTGG CACTCGTCAA CATGATTATG 
TTCTGCACAG GCATCCCTGG CCACTATCCT GTCAATGAGA CCACCAGCTC CCTAACCCTC 
ACCTTCTGGT ACACACTGCA GGATGATATT CTATCCTTTG AGGCAGAGAA GCAGGCTGTA 
TACCAGCAGG TGTACCGGCC AGTCTACTTC CAGCTGGTGG ATGTGCTTCT GCACAAGGCC 
CAGTTCCCTT CTGATGAGGA ATATGGATTC TGGTCCTCAG ACGAGAAGGA GCAGTTCCGA 
ATTTACAGGG TGGACATCTC AGACACGCTC ATGTATGTCT ATGAGATGTT GGGGGCCGAG 
CTGCTCAGCA ACCTCTATGA CAAGCTGGGT CGTTTGCTCA CCAGCTCAGA GGAGCCCTAC 
TCCTGGCAGC ACACAGAGGC CCTCCTCTAC GGCTTCCAAT CCATCGCAGA GACCATTGAC 
GTCAACTATT CTGATGTGGT GCCTGGGCTC ATTGGCCTCA TCCCACGGAT CAGCATCAGC 
AACGTGCAGC TGGCAGACAC TGTCATGTTC ACCATTGGAG CTCTGTCTGA ATGGCTGGCT 
GACCACCCCG TCATGATCAA CAGTGTTCTG CCCTTGGTAC TGCATGCCCT AGGCAATCCT 
GAGCTGTCTG TCTCTTCTGT GTCCACCCTC AAGAAGATCT GCCGAGAGTG CAAGTATGAC 
CTGCCTCCCT ATGCTGCCAA CATTGTGGCT GTGTCCCAGG ATGTGCTGAT GAAACAGATC 
CACAAGACAA GCCAGTGCAT GTGGCTGATG CAGGCGCTGG GCTTCCTGCT GTCAGCTCTT 
CAAGTGGAGG AGATCCTTAA GAACCTGCAC TCGCTTATCT CACCCTATAT CCAGCAACTG 
GAGAAGCTGG CAGAGGAGAT ACCCAATCCC TCCAACAAGC TGGCCATTGT TCACATCTTG 
GGGCTTCTCT CCAACCTCTT CACCACACTG GACATCAGTC ATCATGAGGA TGATCATGAA 
GGCCCTGAGC TTCGGAAGCT GCCAGTGCCA CAGGGACCCA ACCCCGTGGT GGTGGTGCTG 
CAGCAGGTCT TCCAGCTTAT CCAGAAGGTG CTGAGCAAAT GGTTGAATGA TGCCCAGGTT 
GTGGAGGCGG TGTGCGCTAT CTTTGAGAAG TCTGTTAAGA CGCTGCTGGA TGACTTTGCC 
CCCATGGTGC CACAGCTGTG TGAGATGCTG GGTCGGATGT ACAGCACCAT CCCCCAGGCC 
TCTGCTCTTG ACCTCACTCG ACAGCTGGTC CACATCTTTG CTCATGAGCC TGCCCACTTT 
CCCCCAATTG AGGCCCTCTT CCTGCTCGTC ACCTCCGTCA CACTCACTCT CTTCCAGCAA 
GGGCCCAGGG ATCATCCTGA TATTGTTGAT TCATTTATGC AACTCCTGGC ACAGGCTCTG 
AAGCGGAAGC CAGATTTGTT CCTGTGTGAA CGATTGGATG TCAAAGCTGT GTTCCAGTGT 
GCTGTGCTGG CCCTCAAGTT CCCTGAGGCA CCTACTGTCA AGGCCTCCTG TGGCTTCTTT 
ACAGAGCTGC TGCCTCGGTG TGGGGAAGTA GAGTCTGTGG GAAAGGTGGT ACAGGAAGAC 
GGTCGTATGC TGCTCATAGC AGTGCTGGAG GCCATTGGGG GCCAGGCCTC CCGCAGCCTC 
ATGGACTGCT TTGCCGATAT CCTGTTCGCC CTGAACAAGC ACTGCTTCAG CCTCCTGAGC 
ATGTGGATCA AGGAGGCCCT GCAGCCACCT GGTTTCCCCT CTGCCCGCCT CAGCCCTGAA 
CAGAAGGATA CCTTCAGCCA GCAGATCCTT CGCGAGCGAG TGAACAAGAG GCGGGTGAAG 
GAGATGGTGA AGGAGTTCAC ACTGCTGTGC CGGGGTCTCC ATGGCACAGA TTACACAGCT 
GACTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306838.1
CDS	349..2337
Translation	METSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDHEGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDFAPMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGFFTELLPRCGEVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLLSMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYTADY

Target ORF information:

RefSeq Version	XM_024451070.1
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 13 (IPO13), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451070.1

ORF Insert Sequence:

ATGGAGACCT CCCATGGCAT CTGTCGCATC GCTGTGGCCC TGGGCGAGAA CCACTCCCGG 
GCCTTGCTGG ACCAAGTAGA GCACTGGCAG AGTTTCCTGG CACTCGTCAA CATGATTATG 
TTCTGCACAG GCATCCCTGG CCACTATCCT GTCAATGAGA CCACCAGCTC CCTAACCCTC 
ACCTTCTGGT ACACACTGCA GGATGATATT CTATCCTTTG AGGCAGAGAA GCAGGCTGTA 
TACCAGCAGG TGTACCGGCC AGTCTACTTC CAGCTGGTGG ATGTGCTTCT GCACAAGGCC 
CAGTTCCCTT CTGATGAGGA ATATGGATTC TGGTCCTCAG ACGAGAAGGA GCAGTTCCGA 
ATTTACAGGG TGGACATCTC AGACACGCTC ATGTATGTCT ATGAGATGTT GGGGGCCGAG 
CTGCTCAGCA ACCTCTATGA CAAGCTGGGT CGTTTGCTCA CCAGCTCAGA GGAGCCCTAC 
TCCTGGCAGC ACACAGAGGC CCTCCTCTAC GGCTTCCAAT CCATCGCAGA GACCATTGAC 
GTCAACTATT CTGATGTGGT GCCTGGGCTC ATTGGCCTCA TCCCACGGAT CAGCATCAGC 
AACGTGCAGC TGGCAGACAC TGTCATGTTC ACCATTGGAG CTCTGTCTGA ATGGCTGGCT 
GACCACCCCG TCATGATCAA CAGTGTTCTG CCCTTGGTAC TGCATGCCCT AGGCAATCCT 
GAGCTGTCTG TCTCTTCTGT GTCCACCCTC AAGAAGATCT GCCGAGAGTG CAAGTATGAC 
CTGCCTCCCT ATGCTGCCAA CATTGTGGCT GTGTCCCAGG ATGTGCTGAT GAAACAGATC 
CACAAGACAA GCCAGTGCAT GTGGCTGATG CAGGCGCTGG GCTTCCTGCT GTCAGCTCTT 
CAAGTGGAGG AGATCCTTAA GAACCTGCAC TCGCTTATCT CACCCTATAT CCAGCAACTG 
GAGAAGCTGG CAGAGGAGAT ACCCAATCCC TCCAACAAGC TGGCCATTGT TCACATCTTG 
GGGCTTCTCT CCAACCTCTT CACCACACTG GACATCAGTC ATCATGAGGA TGATCATGAA 
GGCCCTGAGC TTCGGAAGCT GCCAGTGCCA CAGGGACCCA ACCCCGTGGT GGTGGTGCTG 
CAGCAGGTCT TCCAGCTTAT CCAGAAGGTG CTGAGCAAAT GGTTGAATGA TGCCCAGGTT 
GTGGAGGCGG TGTGCGCTAT CTTTGAGAAG TCTGTTAAGA CGCTGCTGGA TGACTTTGCC 
CCCATGGTGC CACAGCTGTG TGAGATGCTG GGTCGGATGT ACAGCACCAT CCCCCAGGCC 
TCTGCTCTTG ACCTCACTCG ACAGCTGGTC CACATCTTTG CTCATGAGCC TGCCCACTTT 
CCCCCAATTG AGGCCCTCTT CCTGCTCGTC ACCTCCGTCA CACTCACTCT CTTCCAGCAA 
GGGCCCAGGG ATCATCCTGA TATTGTTGAT TCATTTATGC AACTCCTGGC ACAGGCTCTG 
AAGCGGAAGC CAGATTTGTT CCTGTGTGAA CGATTGGATG TCAAAGCTGT GTTCCAGTGT 
GCTGTGCTGG CCCTCAAGTT CCCTGAGGCA CCTACTGTCA AGGCCTCCTG TGGCTTCTTT 
ACAGAGCTGC TGCCTCGGTG TGGGGAAGTA GAGTCTGTGG GAAAGGTGGT ACAGGAAGAC 
GGTCGTATGC TGCTCATAGC AGTGCTGGAG GCCATTGGGG GCCAGGCCTC CCGCAGCCTC 
ATGGACTGCT TTGCCGATAT CCTGTTCGCC CTGAACAAGC ACTGCTTCAG CCTCCTGAGC 
ATGTGGATCA AGGAGGCCCT GCAGCCACCT GGTTTCCCCT CTGCCCGCCT CAGCCCTGAA 
CAGAAGGATA CCTTCAGCCA GCAGATCCTT CGCGAGCGAG TGAACAAGAG GCGGGTGAAG 
GAGATGGTGA AGGAGTTCAC ACTGCTGTGC CGGGGTCTCC ATGGCACAGA TTACACAGCT 
GACTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO13 ( XM_024451069.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306837.1 Homo sapiens importin 13 (IPO13), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu63124
Clone ID Related Accession (Same CDS sequence)	XM_024451070.1 , XM_024451069.1
Accession Version	XM_024451069.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1989bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	importin-13 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGACCT CCCATGGCAT CTGTCGCATC GCTGTGGCCC TGGGCGAGAA CCACTCCCGG 
GCCTTGCTGG ACCAAGTAGA GCACTGGCAG AGTTTCCTGG CACTCGTCAA CATGATTATG 
TTCTGCACAG GCATCCCTGG CCACTATCCT GTCAATGAGA CCACCAGCTC CCTAACCCTC 
ACCTTCTGGT ACACACTGCA GGATGATATT CTATCCTTTG AGGCAGAGAA GCAGGCTGTA 
TACCAGCAGG TGTACCGGCC AGTCTACTTC CAGCTGGTGG ATGTGCTTCT GCACAAGGCC 
CAGTTCCCTT CTGATGAGGA ATATGGATTC TGGTCCTCAG ACGAGAAGGA GCAGTTCCGA 
ATTTACAGGG TGGACATCTC AGACACGCTC ATGTATGTCT ATGAGATGTT GGGGGCCGAG 
CTGCTCAGCA ACCTCTATGA CAAGCTGGGT CGTTTGCTCA CCAGCTCAGA GGAGCCCTAC 
TCCTGGCAGC ACACAGAGGC CCTCCTCTAC GGCTTCCAAT CCATCGCAGA GACCATTGAC 
GTCAACTATT CTGATGTGGT GCCTGGGCTC ATTGGCCTCA TCCCACGGAT CAGCATCAGC 
AACGTGCAGC TGGCAGACAC TGTCATGTTC ACCATTGGAG CTCTGTCTGA ATGGCTGGCT 
GACCACCCCG TCATGATCAA CAGTGTTCTG CCCTTGGTAC TGCATGCCCT AGGCAATCCT 
GAGCTGTCTG TCTCTTCTGT GTCCACCCTC AAGAAGATCT GCCGAGAGTG CAAGTATGAC 
CTGCCTCCCT ATGCTGCCAA CATTGTGGCT GTGTCCCAGG ATGTGCTGAT GAAACAGATC 
CACAAGACAA GCCAGTGCAT GTGGCTGATG CAGGCGCTGG GCTTCCTGCT GTCAGCTCTT 
CAAGTGGAGG AGATCCTTAA GAACCTGCAC TCGCTTATCT CACCCTATAT CCAGCAACTG 
GAGAAGCTGG CAGAGGAGAT ACCCAATCCC TCCAACAAGC TGGCCATTGT TCACATCTTG 
GGGCTTCTCT CCAACCTCTT CACCACACTG GACATCAGTC ATCATGAGGA TGATCATGAA 
GGCCCTGAGC TTCGGAAGCT GCCAGTGCCA CAGGGACCCA ACCCCGTGGT GGTGGTGCTG 
CAGCAGGTCT TCCAGCTTAT CCAGAAGGTG CTGAGCAAAT GGTTGAATGA TGCCCAGGTT 
GTGGAGGCGG TGTGCGCTAT CTTTGAGAAG TCTGTTAAGA CGCTGCTGGA TGACTTTGCC 
CCCATGGTGC CACAGCTGTG TGAGATGCTG GGTCGGATGT ACAGCACCAT CCCCCAGGCC 
TCTGCTCTTG ACCTCACTCG ACAGCTGGTC CACATCTTTG CTCATGAGCC TGCCCACTTT 
CCCCCAATTG AGGCCCTCTT CCTGCTCGTC ACCTCCGTCA CACTCACTCT CTTCCAGCAA 
GGGCCCAGGG ATCATCCTGA TATTGTTGAT TCATTTATGC AACTCCTGGC ACAGGCTCTG 
AAGCGGAAGC CAGATTTGTT CCTGTGTGAA CGATTGGATG TCAAAGCTGT GTTCCAGTGT 
GCTGTGCTGG CCCTCAAGTT CCCTGAGGCA CCTACTGTCA AGGCCTCCTG TGGCTTCTTT 
ACAGAGCTGC TGCCTCGGTG TGGGGAAGTA GAGTCTGTGG GAAAGGTGGT ACAGGAAGAC 
GGTCGTATGC TGCTCATAGC AGTGCTGGAG GCCATTGGGG GCCAGGCCTC CCGCAGCCTC 
ATGGACTGCT TTGCCGATAT CCTGTTCGCC CTGAACAAGC ACTGCTTCAG CCTCCTGAGC 
ATGTGGATCA AGGAGGCCCT GCAGCCACCT GGTTTCCCCT CTGCCCGCCT CAGCCCTGAA 
CAGAAGGATA CCTTCAGCCA GCAGATCCTT CGCGAGCGAG TGAACAAGAG GCGGGTGAAG 
GAGATGGTGA AGGAGTTCAC ACTGCTGTGC CGGGGTCTCC ATGGCACAGA TTACACAGCT 
GACTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306837.1
CDS	916..2904
Translation	METSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDHEGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDFAPMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGFFTELLPRCGEVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLLSMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYTADY

Target ORF information:

RefSeq Version	XM_024451069.1
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 13 (IPO13), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451069.1

ORF Insert Sequence:

ATGGAGACCT CCCATGGCAT CTGTCGCATC GCTGTGGCCC TGGGCGAGAA CCACTCCCGG 
GCCTTGCTGG ACCAAGTAGA GCACTGGCAG AGTTTCCTGG CACTCGTCAA CATGATTATG 
TTCTGCACAG GCATCCCTGG CCACTATCCT GTCAATGAGA CCACCAGCTC CCTAACCCTC 
ACCTTCTGGT ACACACTGCA GGATGATATT CTATCCTTTG AGGCAGAGAA GCAGGCTGTA 
TACCAGCAGG TGTACCGGCC AGTCTACTTC CAGCTGGTGG ATGTGCTTCT GCACAAGGCC 
CAGTTCCCTT CTGATGAGGA ATATGGATTC TGGTCCTCAG ACGAGAAGGA GCAGTTCCGA 
ATTTACAGGG TGGACATCTC AGACACGCTC ATGTATGTCT ATGAGATGTT GGGGGCCGAG 
CTGCTCAGCA ACCTCTATGA CAAGCTGGGT CGTTTGCTCA CCAGCTCAGA GGAGCCCTAC 
TCCTGGCAGC ACACAGAGGC CCTCCTCTAC GGCTTCCAAT CCATCGCAGA GACCATTGAC 
GTCAACTATT CTGATGTGGT GCCTGGGCTC ATTGGCCTCA TCCCACGGAT CAGCATCAGC 
AACGTGCAGC TGGCAGACAC TGTCATGTTC ACCATTGGAG CTCTGTCTGA ATGGCTGGCT 
GACCACCCCG TCATGATCAA CAGTGTTCTG CCCTTGGTAC TGCATGCCCT AGGCAATCCT 
GAGCTGTCTG TCTCTTCTGT GTCCACCCTC AAGAAGATCT GCCGAGAGTG CAAGTATGAC 
CTGCCTCCCT ATGCTGCCAA CATTGTGGCT GTGTCCCAGG ATGTGCTGAT GAAACAGATC 
CACAAGACAA GCCAGTGCAT GTGGCTGATG CAGGCGCTGG GCTTCCTGCT GTCAGCTCTT 
CAAGTGGAGG AGATCCTTAA GAACCTGCAC TCGCTTATCT CACCCTATAT CCAGCAACTG 
GAGAAGCTGG CAGAGGAGAT ACCCAATCCC TCCAACAAGC TGGCCATTGT TCACATCTTG 
GGGCTTCTCT CCAACCTCTT CACCACACTG GACATCAGTC ATCATGAGGA TGATCATGAA 
GGCCCTGAGC TTCGGAAGCT GCCAGTGCCA CAGGGACCCA ACCCCGTGGT GGTGGTGCTG 
CAGCAGGTCT TCCAGCTTAT CCAGAAGGTG CTGAGCAAAT GGTTGAATGA TGCCCAGGTT 
GTGGAGGCGG TGTGCGCTAT CTTTGAGAAG TCTGTTAAGA CGCTGCTGGA TGACTTTGCC 
CCCATGGTGC CACAGCTGTG TGAGATGCTG GGTCGGATGT ACAGCACCAT CCCCCAGGCC 
TCTGCTCTTG ACCTCACTCG ACAGCTGGTC CACATCTTTG CTCATGAGCC TGCCCACTTT 
CCCCCAATTG AGGCCCTCTT CCTGCTCGTC ACCTCCGTCA CACTCACTCT CTTCCAGCAA 
GGGCCCAGGG ATCATCCTGA TATTGTTGAT TCATTTATGC AACTCCTGGC ACAGGCTCTG 
AAGCGGAAGC CAGATTTGTT CCTGTGTGAA CGATTGGATG TCAAAGCTGT GTTCCAGTGT 
GCTGTGCTGG CCCTCAAGTT CCCTGAGGCA CCTACTGTCA AGGCCTCCTG TGGCTTCTTT 
ACAGAGCTGC TGCCTCGGTG TGGGGAAGTA GAGTCTGTGG GAAAGGTGGT ACAGGAAGAC 
GGTCGTATGC TGCTCATAGC AGTGCTGGAG GCCATTGGGG GCCAGGCCTC CCGCAGCCTC 
ATGGACTGCT TTGCCGATAT CCTGTTCGCC CTGAACAAGC ACTGCTTCAG CCTCCTGAGC 
ATGTGGATCA AGGAGGCCCT GCAGCCACCT GGTTTCCCCT CTGCCCGCCT CAGCCCTGAA 
CAGAAGGATA CCTTCAGCCA GCAGATCCTT CGCGAGCGAG TGAACAAGAG GCGGGTGAAG 
GAGATGGTGA AGGAGTTCAC ACTGCTGTGC CGGGGTCTCC ATGGCACAGA TTACACAGCT 
GACTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.
The Journal of infectious diseases217(1)35-46(2017 Dec)
Xie J,Long X,Gao L,Chen S,Zhao K,Li W,Zhou N,Zang N,Deng Y,Ren L,Wang L,Luo Z,Tu W,Zhao X,Fu Z,Xie X,Liu E

Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.
PloS one11(1)e0146893(2016)
Ansseau E,Eidahl JO,Lancelot C,Tassin A,Matteotti C,Yip C,Liu J,Leroy B,Hubeau C,Gerbaux C,Cloet S,Wauters A,Zorbo S,Meyer P,Pirson I,Laoudj-Chenivesse D,Wattiez R,Harper SQ,Belayew A,Copp?e F

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Nature communications53650(2014 Apr)
Corominas R,Yang X,Lin GN,Kang S,Shen Y,Ghamsari L,Broly M,Rodriguez M,Tam S,Trigg SA,Fan C,Yi S,Tasan M,Lemmens I,Kuang X,Zhao N,Malhotra D,Michaelson JJ,Vacic V,Calderwood MA,Roth FP,Tavernier J,Horvath S,Salehi-Ashtiani K,Korkin D,Sebat J,Hill DE,Hao T,Vidal M,Iakoucheva LM

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IPO13 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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