Gene Symbol | ARHGEF10 |
Entrez Gene ID | 9639 |
Full Name | Rho guanine nucleotide exchange factor 10 |
Synonyms | GEF10,SNCV |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]. |
Disorder MIM: | |
Disorder Html: | ?Slowed nerve conduction velocity, AD, 608236 (3) |