CD38 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CD38
Entrez Gene ID	952
Full Name	CD38 molecule
Synonyms	ADPRC 1,ADPRC1
General protein information	Preferred Names CD38 molecule Names ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2'-phospho-ADP-ribosyl cyclase 2'-phospho-cyclic-ADP-ribose transferase ADP-ribosyl cyclase 1 CD38 antigen (p45) NAD(+) nucleosidase cluster of differentiation 38 cyclic ADP-ribose hydrolase 1 ecto-nicotinamide adenine dinucleotide glycohydrolase
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 4 Map Location: 4p15.32
Summary	The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].
Disorder MIM:	107270

mRNA and Protein(s)

mRNA	Protein	Name
NM_001775.4	NP_001766.2	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
NM_001775.3	NP_001766.2	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
NM_001775.2	NP_001766.2	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Pathways from BioSystems

Homologies

	CD38	XP_001099851.1
Mus musculus (house mouse)	Cd38	NP_031672.2
Rattus norvegicus (Norway rat)	Cd38	NP_037259.1
Gallus gallus (chicken)	CD38	NP_001188317.1
Homo sapiens (human)	CD38	NP_001766.2
Danio rerio (zebrafish)	LOC101886891	XP_005162637.1
Xenopus tropicalis (tropical clawed frog)	cd38	NP_001011230.1
Pan troglodytes (chimpanzee)	CD38	XP_001160669.1
Canis lupus familiaris (dog)	CD38	NP_001003143.1

Gene Ontology
Bibliography

Related articles in PubMed

CD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions.
Liao S, Xiao S, Chen H, Zhang M, Chen Z, Long Y, Gao L, Zhu G, He J, Peng S, Xiong W, Zeng Z, Li Z, Zhou M, Li X, Ma J, Wu M, Xiang J, Li G, Zhou Y
Molecular carcinogenesis56(10)2245-2257(2017 Oct)

ADP ribosyl-cyclases (CD38/CD157), social skills and friendship.
Chong A, Malavasi F, Israel S, Khor CC, Yap VB, Monakhov M, Chew SH, Lai PS, Ebstein RP
Psychoneuroendocrinology78185-192(2017 Apr)

The membrane-bound enzyme CD38 exists in two opposing orientations.
Zhao YJ, Lam CM, Lee HC
Science signaling5(241)ra67(2012 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results provide evidence that CD38 enhanced the proliferation and inhibited the apoptosis of cervical cancer cells by affecting the mitochondria functions.
Title: CD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions.

Anti-CD19-chimeric antigen receptors T cells synergistically exerted collaborative cytotoxicity against primary double-hit lymphoma cells with anti-CD38-chimeric antigen receptors T cells.
Title: T cells bearing anti-CD19 and/or anti-CD38 chimeric antigen receptors effectively abrogate primary double-hit lymphoma cells.

CD38 mRNA levels were correlated with lower Autism Quotient (AQ), indicating enhanced social skills. CD38 expression and CD157 eQTL SNPs altogether account for a substantial 14% of the variance in sociality. the ecological validity of these findings was demonstrated with subjects with higher PBL CD38 expression having more friends, especially for males.
Title: ADP ribosyl-cyclases (CD38/CD157), social skills and friendship.

CD38, BCL-2, PD-1, and PD-1L expression in nodal peripheral T-cell lymphoma
Title: CD38, BCL-2, PD-1, and PD-1L expression in nodal peripheral T-cell lymphoma: Possible biomarkers for novel targeted therapies?

CD38(lo) luminal cells are enriched in glands adjacent to inflammatory cells and exhibit epithelial nuclear factor kappaB (NF-kappaB) signaling. In response to oncogenic transformation, CD38(lo) luminal cells can initiate human prostate cancer in an in vivo tissue-regeneration assay
Title: Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome.

The following CD38 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD38 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27796	NM_001775.4 Latest version!	Homo sapiens CD38 molecule (CD38), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu27796	NM_001775.3	Homo sapiens CD38 molecule (CD38), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu27796	NM_001775.2	Homo sapiens CD38 molecule (CD38), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CD38 ( NM_001775.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001766.2 Homo sapiens CD38 molecule (CD38), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27796
Clone ID Related Accession (Same CDS sequence)	NM_001775.4 , NM_001775.3 , NM_001775.2
Accession Version	NM_001775.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK303169.1, BC007964.2 and AC005798.10. On Nov 22, 2018 this sequence version replaced NM_001775.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.271551.1, SRR1660805.73007.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000226279.8/ ENSP00000226279.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCAACT GCGAGTTCAG CCCGGTGTCC GGGGACAAAC CCTGCTGCCG GCTCTCTAGG 
AGAGCCCAAC TCTGTCTTGG CGTCAGTATC CTGGTCCTGA TCCTCGTCGT GGTGCTCGCG 
GTGGTCGTCC CGAGGTGGCG CCAGCAGTGG AGCGGTCCGG GCACCACCAA GCGCTTTCCC 
GAGACCGTCC TGGCGCGATG CGTCAAGTAC ACTGAAATTC ATCCTGAGAT GAGACATGTA 
GACTGCCAAA GTGTATGGGA TGCTTTCAAG GGTGCATTTA TTTCAAAACA TCCTTGCAAC 
ATTACTGAAG AAGACTATCA GCCACTAATG AAGTTGGGAA CTCAGACCGT ACCTTGCAAC 
AAGATTCTTC TTTGGAGCAG AATAAAAGAT CTGGCCCATC AGTTCACACA GGTCCAGCGG 
GACATGTTCA CCCTGGAGGA CACGCTGCTA GGCTACCTTG CTGATGACCT CACATGGTGT 
GGTGAATTCA ACACTTCCAA AATAAACTAT CAATCTTGCC CAGACTGGAG AAAGGACTGC 
AGCAACAACC CTGTTTCAGT ATTCTGGAAA ACGGTTTCCC GCAGGTTTGC AGAAGCTGCC 
TGTGATGTGG TCCATGTGAT GCTCAATGGA TCCCGCAGTA AAATCTTTGA CAAAAACAGC 
ACTTTTGGGA GTGTGGAAGT CCATAATTTG CAACCAGAGA AGGTTCAGAC ACTAGAGGCC 
TGGGTGATAC ATGGTGGAAG AGAAGATTCC AGAGACTTAT GCCAGGATCC CACCATAAAA 
GAGCTGGAAT CGATTATAAG CAAAAGGAAT ATTCAATTTT CCTGCAAGAA TATCTACAGA 
CCTGACAAGT TTCTTCAGTG TGTGAAAAAT CCTGAGGATT CATCTTGCAC ATCTGAGATC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001766.2
CDS	88..990
Translation	MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI

Target ORF information:

RefSeq Version	NM_001775.4
Organism	Homo sapiens(human)
Definition	Homo sapiens CD38 molecule (CD38), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001775.4

ORF Insert Sequence:

ATGGCCAACT GCGAGTTCAG CCCGGTGTCC GGGGACAAAC CCTGCTGCCG GCTCTCTAGG 
AGAGCCCAAC TCTGTCTTGG CGTCAGTATC CTGGTCCTGA TCCTCGTCGT GGTGCTCGCG 
GTGGTCGTCC CGAGGTGGCG CCAGCAGTGG AGCGGTCCGG GCACCACCAA GCGCTTTCCC 
GAGACCGTCC TGGCGCGATG CGTCAAGTAC ACTGAAATTC ATCCTGAGAT GAGACATGTA 
GACTGCCAAA GTGTATGGGA TGCTTTCAAG GGTGCATTTA TTTCAAAACA TCCTTGCAAC 
ATTACTGAAG AAGACTATCA GCCACTAATG AAGTTGGGAA CTCAGACCGT ACCTTGCAAC 
AAGATTCTTC TTTGGAGCAG AATAAAAGAT CTGGCCCATC AGTTCACACA GGTCCAGCGG 
GACATGTTCA CCCTGGAGGA CACGCTGCTA GGCTACCTTG CTGATGACCT CACATGGTGT 
GGTGAATTCA ACACTTCCAA AATAAACTAT CAATCTTGCC CAGACTGGAG AAAGGACTGC 
AGCAACAACC CTGTTTCAGT ATTCTGGAAA ACGGTTTCCC GCAGGTTTGC AGAAGCTGCC 
TGTGATGTGG TCCATGTGAT GCTCAATGGA TCCCGCAGTA AAATCTTTGA CAAAAACAGC 
ACTTTTGGGA GTGTGGAAGT CCATAATTTG CAACCAGAGA AGGTTCAGAC ACTAGAGGCC 
TGGGTGATAC ATGGTGGAAG AGAAGATTCC AGAGACTTAT GCCAGGATCC CACCATAAAA 
GAGCTGGAAT CGATTATAAG CAAAAGGAAT ATTCAATTTT CCTGCAAGAA TATCTACAGA 
CCTGACAAGT TTCTTCAGTG TGTGAAAAAT CCTGAGGATT CATCTTGCAC ATCTGAGATC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD38 ( NM_001775.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001766.2 Homo sapiens CD38 molecule (CD38), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27796
Clone ID Related Accession (Same CDS sequence)	NM_001775.4 , NM_001775.3 , NM_001775.2
Accession Version	NM_001775.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005798.10, AK303169.1 and BC007964.2. On Sep 10, 2015 this sequence version replaced NM_001775.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.73007.1, SRR1660805.234674.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCCAACT GCGAGTTCAG CCCGGTGTCC GGGGACAAAC CCTGCTGCCG GCTCTCTAGG 
AGAGCCCAAC TCTGTCTTGG CGTCAGTATC CTGGTCCTGA TCCTCGTCGT GGTGCTCGCG 
GTGGTCGTCC CGAGGTGGCG CCAGCAGTGG AGCGGTCCGG GCACCACCAA GCGCTTTCCC 
GAGACCGTCC TGGCGCGATG CGTCAAGTAC ACTGAAATTC ATCCTGAGAT GAGACATGTA 
GACTGCCAAA GTGTATGGGA TGCTTTCAAG GGTGCATTTA TTTCAAAACA TCCTTGCAAC 
ATTACTGAAG AAGACTATCA GCCACTAATG AAGTTGGGAA CTCAGACCGT ACCTTGCAAC 
AAGATTCTTC TTTGGAGCAG AATAAAAGAT CTGGCCCATC AGTTCACACA GGTCCAGCGG 
GACATGTTCA CCCTGGAGGA CACGCTGCTA GGCTACCTTG CTGATGACCT CACATGGTGT 
GGTGAATTCA ACACTTCCAA AATAAACTAT CAATCTTGCC CAGACTGGAG AAAGGACTGC 
AGCAACAACC CTGTTTCAGT ATTCTGGAAA ACGGTTTCCC GCAGGTTTGC AGAAGCTGCC 
TGTGATGTGG TCCATGTGAT GCTCAATGGA TCCCGCAGTA AAATCTTTGA CAAAAACAGC 
ACTTTTGGGA GTGTGGAAGT CCATAATTTG CAACCAGAGA AGGTTCAGAC ACTAGAGGCC 
TGGGTGATAC ATGGTGGAAG AGAAGATTCC AGAGACTTAT GCCAGGATCC CACCATAAAA 
GAGCTGGAAT CGATTATAAG CAAAAGGAAT ATTCAATTTT CCTGCAAGAA TATCTACAGA 
CCTGACAAGT TTCTTCAGTG TGTGAAAAAT CCTGAGGATT CATCTTGCAC ATCTGAGATC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001766.2
CDS	151..1053
Translation	MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI

Target ORF information:

RefSeq Version	NM_001775.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CD38 molecule (CD38), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001775.3

ORF Insert Sequence:

ATGGCCAACT GCGAGTTCAG CCCGGTGTCC GGGGACAAAC CCTGCTGCCG GCTCTCTAGG 
AGAGCCCAAC TCTGTCTTGG CGTCAGTATC CTGGTCCTGA TCCTCGTCGT GGTGCTCGCG 
GTGGTCGTCC CGAGGTGGCG CCAGCAGTGG AGCGGTCCGG GCACCACCAA GCGCTTTCCC 
GAGACCGTCC TGGCGCGATG CGTCAAGTAC ACTGAAATTC ATCCTGAGAT GAGACATGTA 
GACTGCCAAA GTGTATGGGA TGCTTTCAAG GGTGCATTTA TTTCAAAACA TCCTTGCAAC 
ATTACTGAAG AAGACTATCA GCCACTAATG AAGTTGGGAA CTCAGACCGT ACCTTGCAAC 
AAGATTCTTC TTTGGAGCAG AATAAAAGAT CTGGCCCATC AGTTCACACA GGTCCAGCGG 
GACATGTTCA CCCTGGAGGA CACGCTGCTA GGCTACCTTG CTGATGACCT CACATGGTGT 
GGTGAATTCA ACACTTCCAA AATAAACTAT CAATCTTGCC CAGACTGGAG AAAGGACTGC 
AGCAACAACC CTGTTTCAGT ATTCTGGAAA ACGGTTTCCC GCAGGTTTGC AGAAGCTGCC 
TGTGATGTGG TCCATGTGAT GCTCAATGGA TCCCGCAGTA AAATCTTTGA CAAAAACAGC 
ACTTTTGGGA GTGTGGAAGT CCATAATTTG CAACCAGAGA AGGTTCAGAC ACTAGAGGCC 
TGGGTGATAC ATGGTGGAAG AGAAGATTCC AGAGACTTAT GCCAGGATCC CACCATAAAA 
GAGCTGGAAT CGATTATAAG CAAAAGGAAT ATTCAATTTT CCTGCAAGAA TATCTACAGA 
CCTGACAAGT TTCTTCAGTG TGTGAAAAAT CCTGAGGATT CATCTTGCAC ATCTGAGATC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD38 ( NM_001775.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001766.2 Homo sapiens CD38 molecule (CD38), mRNA.

Price & Availability↑

CloneID	OHu27796
Clone ID Related Accession (Same CDS sequence)	NM_001775.4 , NM_001775.3 , NM_001775.2
Accession Version	NM_001775.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Comment

ATGGCCAACT GCGAGTTCAG CCCGGTGTCC GGGGACAAAC CCTGCTGCCG GCTCTCTAGG 
AGAGCCCAAC TCTGTCTTGG CGTCAGTATC CTGGTCCTGA TCCTCGTCGT GGTGCTCGCG 
GTGGTCGTCC CGAGGTGGCG CCAGCAGTGG AGCGGTCCGG GCACCACCAA GCGCTTTCCC 
GAGACCGTCC TGGCGCGATG CGTCAAGTAC ACTGAAATTC ATCCTGAGAT GAGACATGTA 
GACTGCCAAA GTGTATGGGA TGCTTTCAAG GGTGCATTTA TTTCAAAACA TCCTTGCAAC 
ATTACTGAAG AAGACTATCA GCCACTAATG AAGTTGGGAA CTCAGACCGT ACCTTGCAAC 
AAGATTCTTC TTTGGAGCAG AATAAAAGAT CTGGCCCATC AGTTCACACA GGTCCAGCGG 
GACATGTTCA CCCTGGAGGA CACGCTGCTA GGCTACCTTG CTGATGACCT CACATGGTGT 
GGTGAATTCA ACACTTCCAA AATAAACTAT CAATCTTGCC CAGACTGGAG AAAGGACTGC 
AGCAACAACC CTGTTTCAGT ATTCTGGAAA ACGGTTTCCC GCAGGTTTGC AGAAGCTGCC 
TGTGATGTGG TCCATGTGAT GCTCAATGGA TCCCGCAGTA AAATCTTTGA CAAAAACAGC 
ACTTTTGGGA GTGTGGAAGT CCATAATTTG CAACCAGAGA AGGTTCAGAC ACTAGAGGCC 
TGGGTGATAC ATGGTGGAAG AGAAGATTCC AGAGACTTAT GCCAGGATCC CACCATAAAA 
GAGCTGGAAT CGATTATAAG CAAAAGGAAT ATTCAATTTT CCTGCAAGAA TATCTACAGA 
CCTGACAAGT TTCTTCAGTG TGTGAAAAAT CCTGAGGATT CATCTTGCAC ATCTGAGATC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001766.2
Translation	MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI

Target ORF information:

RefSeq Version	NM_001775.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens CD38 molecule (CD38), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001775.2

ORF Insert Sequence:

ATGGCCAACT GCGAGTTCAG CCCGGTGTCC GGGGACAAAC CCTGCTGCCG GCTCTCTAGG 
AGAGCCCAAC TCTGTCTTGG CGTCAGTATC CTGGTCCTGA TCCTCGTCGT GGTGCTCGCG 
GTGGTCGTCC CGAGGTGGCG CCAGCAGTGG AGCGGTCCGG GCACCACCAA GCGCTTTCCC 
GAGACCGTCC TGGCGCGATG CGTCAAGTAC ACTGAAATTC ATCCTGAGAT GAGACATGTA 
GACTGCCAAA GTGTATGGGA TGCTTTCAAG GGTGCATTTA TTTCAAAACA TCCTTGCAAC 
ATTACTGAAG AAGACTATCA GCCACTAATG AAGTTGGGAA CTCAGACCGT ACCTTGCAAC 
AAGATTCTTC TTTGGAGCAG AATAAAAGAT CTGGCCCATC AGTTCACACA GGTCCAGCGG 
GACATGTTCA CCCTGGAGGA CACGCTGCTA GGCTACCTTG CTGATGACCT CACATGGTGT 
GGTGAATTCA ACACTTCCAA AATAAACTAT CAATCTTGCC CAGACTGGAG AAAGGACTGC 
AGCAACAACC CTGTTTCAGT ATTCTGGAAA ACGGTTTCCC GCAGGTTTGC AGAAGCTGCC 
TGTGATGTGG TCCATGTGAT GCTCAATGGA TCCCGCAGTA AAATCTTTGA CAAAAACAGC 
ACTTTTGGGA GTGTGGAAGT CCATAATTTG CAACCAGAGA AGGTTCAGAC ACTAGAGGCC 
TGGGTGATAC ATGGTGGAAG AGAAGATTCC AGAGACTTAT GCCAGGATCC CACCATAAAA 
GAGCTGGAAT CGATTATAAG CAAAAGGAAT ATTCAATTTT CCTGCAAGAA TATCTACAGA 
CCTGACAAGT TTCTTCAGTG TGTGAAAAAT CCTGAGGATT CATCTTGCAC ATCTGAGATC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions.
Molecular carcinogenesis56(10)2245-2257(2017 Oct)
Liao S,Xiao S,Chen H,Zhang M,Chen Z,Long Y,Gao L,Zhu G,He J,Peng S,Xiong W,Zeng Z,Li Z,Zhou M,Li X,Ma J,Wu M,Xiang J,Li G,Zhou Y

ADP ribosyl-cyclases (CD38/CD157), social skills and friendship.
Psychoneuroendocrinology78185-192(2017 Apr)
Chong A,Malavasi F,Israel S,Khor CC,Yap VB,Monakhov M,Chew SH,Lai PS,Ebstein RP

The membrane-bound enzyme CD38 exists in two opposing orientations.
Science signaling5(241)ra67(2012 Sep)
Zhao YJ,Lam CM,Lee HC

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CD38 cDNA ORF clone, Homo sapiens(Human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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