PMPCB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PMPCB
Entrez Gene ID	9512
Full Name	peptidase, mitochondrial processing beta subunit
Synonyms	Beta-MPP,MPP11,MPPB,MPPP52,P-52
General protein information	Preferred Names peptidase, mitochondrial processing beta subunit Names mitochondrial-processing peptidase subunit beta mitochondrial processing peptidase beta subunit peptidase (mitochondrial processing) beta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q22.1
Summary	This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. [provided by RefSeq, Jul 2008].
Disorder MIM:	603131

mRNA and Protein(s)

mRNA	Protein	Name
XM_006716181.3	XP_006716244.1	mitochondrial-processing peptidase subunit beta isoform X2
NM_004279.3	NP_004270.2	mitochondrial-processing peptidase subunit beta precursor
XM_005250717.3	XP_005250774.1	mitochondrial-processing peptidase subunit beta isoform X1
NM_004279.2	NP_004270.2	mitochondrial-processing peptidase subunit beta precursor
XM_005250717.4	XP_005250774.1	mitochondrial-processing peptidase subunit beta isoform X1
XM_006716181.4	XP_006716244.1	mitochondrial-processing peptidase subunit beta isoform X2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Pmpcb	NP_071790.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000935	XP_309120.4
Neurospora crassa	NCU02549	XP_965680.1
Arabidopsis thaliana (thale cress)	MPPBETA	NP_186858.1
Caenorhabditis elegans (roundworm)	mppb-1	NP_501576.2
Homo sapiens (human)	PMPCB	NP_004270.2
Pan troglodytes (chimpanzee)	PMPCB	XP_001160333.2
Mus musculus (house mouse)	Pmpcb	NP_082707.1
Gallus gallus (chicken)	PMPCB	NP_001186401.1
Danio rerio (zebrafish)	pmpcb	NP_001012514.1
Kluyveromyces lactis	KLLA0D18095g	XP_453861.1
Eremothecium gossypii	AGOS_AGL138C	NP_986529.1
Schizosaccharomyces pombe (fission yeast)	qcr1	NP_595827.1
Magnaporthe oryzae (rice blast fungus)	MGG_03600	XP_003716305.1
Canis lupus familiaris (dog)	PMPCB	XP_005631033.1
Saccharomyces cerevisiae (baker's yeast)	MAS1	NP_013264.1
Oryza sativa (rice)	Os03g0212700	NP_001049357.1
Xenopus tropicalis (tropical clawed frog)	pmpcb	NP_001039103.1
Bos taurus (cattle)	PMPCB	NP_001029785.1
Drosophila melanogaster (fruit fly)	CG3731	NP_731954.1

Gene Ontology
Bibliography

Related articles in PubMed

OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase.
Pandey D, Bhunia A, Oh YJ, Chang F, Bergman Y, Kim JH, Serbo J, Boronina TN, Cole RN, Van Eyk J, Remaley AT, Berkowitz DE, Romer LH
Circulation research115(4)450-9(2014 Aug)

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
Greene AW, Grenier K, Aguileta MA, Muise S, Farazifard R, Haque ME, McBride HM, Park DS, Fon EA
EMBO reports13(4)378-85(2012 Apr)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Acute lymphoblastic leukemia-derived dendritic cells express tumor associated antigens: PNPT1, PMPCB, RHAMM, BSG and ERCC1.
Luczynski W, Kowalczuk O, Stasiak-Barmuta A, Ilendo E, Krawczuk-Rybak M, Chyczewski L
Neoplasma56(5)428-34(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase.
Title: OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase.

These results highlight a new role for MPP in PINK1 import and mitochondrial quality control via the PINK1-Parkin pathway.
Title: Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

maintained expression and even up-regulation of some (PNPT1, PMPCB, HMMR/RHAMM, BSG and ERCC1) tumor associated antigens in CD40-activated leukemic cells.
Title: Acute lymphoblastic leukemia-derived dendritic cells express tumor associated antigens: PNPT1, PMPCB, RHAMM, BSG and ERCC1.

The following PMPCB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PMPCB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30080	NM_004279.3 Latest version!	Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$286.30 $409.00
OHu41873	XM_005250717.4 Latest version!	Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu41874	XM_006716181.4 Latest version!	Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu30080	NM_004279.2	Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$286.30 $409.00
OHu41873	XM_005250717.3	Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu41874	XM_006716181.3	Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PMPCB ( NM_004279.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004270.2 Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), mRNA.

Price & Availability↑

CloneID	OHu30080
Clone ID Related Accession (Same CDS sequence)	NM_004279.3 , NM_004279.2
Accession Version	NM_004279.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-26
Organism	Homo sapiens(human)
Product	mitochondrial-processing peptidase subunit beta precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP311561.1, AK000994.1, BC014079.2, AF054182.1, AC004668.1 and AI261792.1. On Nov 22, 2018 this sequence version replaced NM_004279.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.164164.1, SRR1803615.112289.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000249269.9/ ENSP00000249269.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGTCCC ATTAAGCAAC TACCAGATTT TAAACAGATA 
CGCAGTAACA TGTGTTGGCT TCGTGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004270.2
CDS	26..1495
Translation	MAAAAARVVLSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGPIKQLPDFKQIRSNMCWLRD

Target ORF information:

RefSeq Version	NM_004279.3
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004279.3

ORF Insert Sequence:

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGTCCC ATTAAGCAAC TACCAGATTT TAAACAGATA 
CGCAGTAACA TGTGTTGGCT TCGTGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PMPCB ( NM_004279.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004270.2 Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), mRNA.

Price & Availability↑

CloneID	OHu30080
Clone ID Related Accession (Same CDS sequence)	NM_004279.3 , NM_004279.2
Accession Version	NM_004279.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	mitochondrial-processing peptidase subunit beta precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP311561.1, AK000994.1, BC014079.2, AF054182.1, AC004668.1 and AI261792.1. On May 4, 2006 this sequence version replaced NM_004279.1. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.112289.1, SRR1803617.142522.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGTCCC ATTAAGCAAC TACCAGATTT TAAACAGATA 
CGCAGTAACA TGTGTTGGCT TCGTGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004270.2
CDS	35..1504
Translation	MAAAAARVVLSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGPIKQLPDFKQIRSNMCWLRD

Target ORF information:

RefSeq Version	NM_004279.2
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004279.2

ORF Insert Sequence:

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGTCCC ATTAAGCAAC TACCAGATTT TAAACAGATA 
CGCAGTAACA TGTGTTGGCT TCGTGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PMPCB ( XM_005250717.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005250774.1 Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu41873
Clone ID Related Accession (Same CDS sequence)	XM_005250717.3 , XM_005250717.4
Accession Version	XM_005250717.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	mitochondrial-processing peptidase subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005250717.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGATAT AATCACAGAA GTGAACTTCA TGAATGGAAA 
TGGAACAAGT TATTTTCCAA AAGGCAAACT ATTTCATACT CCTACGTGAA CATCCTTTTA 
CCACAGCCTC AGCCACAGTA CGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005250774.1
CDS	49..1575
Translation	MAAAAARVVLSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGYNHRSELHEWKWNKLFSKRQTISYSYVNILLPQPQPQYV

Target ORF information:

RefSeq Version	XM_005250717.3
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005250717.3

ORF Insert Sequence:

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGATAT AATCACAGAA GTGAACTTCA TGAATGGAAA 
TGGAACAAGT TATTTTCCAA AAGGCAAACT ATTTCATACT CCTACGTGAA CATCCTTTTA 
CCACAGCCTC AGCCACAGTA CGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PMPCB ( XM_005250717.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005250774.1 Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu41873
Clone ID Related Accession (Same CDS sequence)	XM_005250717.3 , XM_005250717.4
Accession Version	XM_005250717.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mitochondrial-processing peptidase subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005250717.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGATAT AATCACAGAA GTGAACTTCA TGAATGGAAA 
TGGAACAAGT TATTTTCCAA AAGGCAAACT ATTTCATACT CCTACGTGAA CATCCTTTTA 
CCACAGCCTC AGCCACAGTA CGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005250774.1
CDS	26..1552
Translation	MAAAAARVVLSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGYNHRSELHEWKWNKLFSKRQTISYSYVNILLPQPQPQYV

Target ORF information:

RefSeq Version	XM_005250717.4
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005250717.4

ORF Insert Sequence:

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGATAT AATCACAGAA GTGAACTTCA TGAATGGAAA 
TGGAACAAGT TATTTTCCAA AAGGCAAACT ATTTCATACT CCTACGTGAA CATCCTTTTA 
CCACAGCCTC AGCCACAGTA CGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PMPCB ( XM_006716181.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006716244.1 Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu41874
Clone ID Related Accession (Same CDS sequence)	XM_006716181.3 , XM_006716181.4
Accession Version	XM_006716181.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	mitochondrial-processing peptidase subunit beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006716181.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGATAT AATCACAGAA GTGAACTTCA TGAATGGAAA 
TGGAACAAGT TATTTTCCAA AAGGCAAACT ATTTCATACT CCTACGTGAA CATCCTTTTA 
CCACAGCCTC AGCCACAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006716244.1
CDS	48..1568
Translation	MAAAAARVVLSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGYNHRSELHEWKWNKLFSKRQTISYSYVNILLPQPQPQ

Target ORF information:

RefSeq Version	XM_006716181.3
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase, mitochondrial processing beta subunit (PMPCB), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006716181.3

ORF Insert Sequence:

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGATAT AATCACAGAA GTGAACTTCA TGAATGGAAA 
TGGAACAAGT TATTTTCCAA AAGGCAAACT ATTTCATACT CCTACGTGAA CATCCTTTTA 
CCACAGCCTC AGCCACAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PMPCB ( XM_006716181.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006716244.1 Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu41874
Clone ID Related Accession (Same CDS sequence)	XM_006716181.3 , XM_006716181.4
Accession Version	XM_006716181.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mitochondrial-processing peptidase subunit beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006716181.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGATAT AATCACAGAA GTGAACTTCA TGAATGGAAA 
TGGAACAAGT TATTTTCCAA AAGGCAAACT ATTTCATACT CCTACGTGAA CATCCTTTTA 
CCACAGCCTC AGCCACAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006716244.1
CDS	26..1546
Translation	MAAAAARVVLSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGYNHRSELHEWKWNKLFSKRQTISYSYVNILLPQPQPQ

Target ORF information:

RefSeq Version	XM_006716181.4
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase, mitochondrial processing subunit beta (PMPCB), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006716181.4

ORF Insert Sequence:

ATGGCGGCTG CGGCGGCTCG AGTGGTGTTG TCATCCGCGG CGCGGCGGCG GCTCTGGGGT 
TTCAGCGAGA GTCTTCTAAT CCGAGGCGCT GCGGGACGGT CATTATATTT TGGAGAGAAC 
AGATTAAGAA GTACACAGGC TGCTACCCAA GTTGTTCTGA ATGTTCCTGA AACAAGAGTA 
ACATGTTTAG AAAGTGGACT CAGAGTAGCT TCGGAAGACT CTGGGCTCTC AACATGCACA 
GTTGGACTCT GGATTGATGC TGGAAGTAGA TACGAAAATG AGAAGAACAA TGGAACAGCA 
CACTTTCTGG AGCATATGGC TTTCAAGGGC ACCAAGAAGA GATCCCAGTT AGATCTGGAA 
CTTGAGATTG AAAATATGGG TGCTCATCTC AATGCCTATA CCTCCAGAGA GCAGACTGTA 
TACTATGCCA AAGCATTCTC TAAAGACTTG CCAAGAGCTG TAGAAATTCT TGCTGATATA 
ATACAAAACA GCACATTGGG AGAAGCAGAG ATTGAACGTG AGCGTGGAGT AATCCTTAGA 
GAGATGCAGG AAGTTGAAAC CAATTTACAA GAAGTTGTTT TTGATTATCT TCATGCCACA 
GCTTATCAAA ATACTGCACT TGGACGGACA ATTTTGGGAC CAACTGAAAA TATCAAATCT 
ATAAGTCGTA AGGACTTAGT GGATTATATA ACCACACATT ATAAGGGGCC AAGAATAGTG 
CTTGCTGCTG CTGGAGGTGT TTCCCATGAT GAATTGCTTG ACTTAGCAAA GTTTCATTTC 
GGTGACTCTT TATGCACACA CAAAGGAGAA ATACCAGCTC TGCCTCCCTG CAAATTCACA 
GGAAGTGAGA TTCGTGTGAG GGATGACAAG ATGCCTTTGG CGCACCTTGC AATAGCTGTT 
GAAGCTGTTG GTTGGGCACA TCCAGATACA ATCTGTCTCA TGGTTGCAAA CACGCTGATT 
GGCAACTGGG ATCGCTCTTT TGGGGGAGGA ATGAATTTAT CTAGCAAGCT GGCCCAGCTC 
ACTTGTCATG GCAATCTTTG CCATAGCTTT CAGTCTTTCA ACACTTCCTA CACAGATACA 
GGATTATGGG GACTGTATAT GGTTTGTGAA TCATCCACTG TTGCAGACAT GCTACATGTT 
GTTCAAAAAG AATGGATGCG ACTCTGTACA AGTGTCACAG AAAGTGAGGT TGCACGAGCC 
AGAAATCTTC TGAAAACAAA CATGTTGTTG CAGCTTGATG GTTCAACTCC AATTTGTGAA 
GATATTGGTA GGCAAATGTT ATGCTATAAT AGAAGGATTC CCATCCCTGA GCTTGAAGCA 
AGAATTGATG CTGTGAATGC TGAGACAATT CGAGAAGTAT GTACCAAATA CATTTATAAT 
AGGAGTCCAG CTATTGCTGC TGTTGGATAT AATCACAGAA GTGAACTTCA TGAATGGAAA 
TGGAACAAGT TATTTTCCAA AAGGCAAACT ATTTCATACT CCTACGTGAA CATCCTTTTA 
CCACAGCCTC AGCCACAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase.
Circulation research115(4)450-9(2014 Aug)
Pandey D,Bhunia A,Oh YJ,Chang F,Bergman Y,Kim JH,Serbo J,Boronina TN,Cole RN,Van Eyk J,Remaley AT,Berkowitz DE,Romer LH

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
EMBO reports13(4)378-85(2012 Apr)
Greene AW,Grenier K,Aguileta MA,Muise S,Farazifard R,Haque ME,McBride HM,Park DS,Fon EA

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

Acute lymphoblastic leukemia-derived dendritic cells express tumor associated antigens: PNPT1, PMPCB, RHAMM, BSG and ERCC1.
Neoplasma56(5)428-34(2009)
Luczynski W,Kowalczuk O,Stasiak-Barmuta A,Ilendo E,Krawczuk-Rybak M,Chyczewski L

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PMPCB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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