ADAMTS2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAMTS2
Entrez Gene ID	9509
Full Name	ADAM metallopeptidase with thrombospondin type 1 motif 2
Synonyms	ADAM-TS2,ADAMTS-2,ADAMTS-3,EDSDERMS,NPI,PC I-NP,PCI-NP,PCINP,PCPNI,PNPI
General protein information	Preferred Names ADAM metallopeptidase with thrombospondin type 1 motif 2 Names A disintegrin and metalloproteinase with thrombospondin motifs 2 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2 procollagen I N-proteinase procollagen I/II amino propeptide-processing enzyme procollagen N-endopeptidase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q35.3
Summary	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016].
Disorder MIM:	604539
Disorder Html:	Ehlers-Danlos syndrome, type VIIC, 225410 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_021599.3	NP_067610.1	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 2 precursor
NM_021599.4	NP_067610.1	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 2 precursor
NM_021599.2	NP_067610.1	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 2 preproprotein
XM_017010063.1	XP_016865552.1	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X1
NM_014244.4	NP_055059.2	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 1 preproprotein
NM_014244.5	NP_055059.2	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 1 preproprotein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ADAMTS2	XP_518147.2
	ADAMTS2	XP_001102920.2
Danio rerio (zebrafish)	adamts22	XP_700384.3
Homo sapiens (human)	ADAMTS2	NP_055059.2
Canis lupus familiaris (dog)	ADAMTS2	XP_848937.1
Gallus gallus (chicken)	ADAMTS2	XP_414611.4
Xenopus tropicalis (tropical clawed frog)	LOC100492431	XP_002933681.2
Bos taurus (cattle)	ADAMTS2	NP_777056.1
Mus musculus (house mouse)	Adamts2	NP_783574.1
Rattus norvegicus (Norway rat)	Adamts2	NP_001131094.1

Gene Ontology
Bibliography

Related articles in PubMed

Expanding the clinical and mutational spectrum of the Ehlers-Danlos syndrome, dermatosparaxis type.
Van Damme T, Colige A, Syx D, Giunta C, Lindert U, Rohrbach M, Aryani O, Alanay Y, Simsek-Kiper P?, Kroes HY, Devriendt K, Thiry M, Symoens S, De Paepe A, Malfait F
Genetics in medicine : official journal of the American College of Medical Genetics18(9)882-91(2016 Sep)

Induction of human ADAMTS-2 gene expression by IL-1? is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells.
Alper M, Aydemir AT, K??kar F
Gene573(2)321-7(2015 Dec)

The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.
Bekhouche M, Colige A
Matrix biology : journal of the International Society for Matrix Biology44-4646-53(2015 May-Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We identified three novel homozygous loss-of-function mutations (c.2927_2928delCT, p.(Pro976Argfs*42); c.669_670dupG, p.(Pro224Argfs*24); and c.2751-2A>T) and one compound heterozygous mutation (c.2T>C, p.? and c.884_887delTGAA, p.(Met295Thrfs26*)) in ADAMTS2 in five patients from four unrelated families
Title: Expanding the clinical and mutational spectrum of the Ehlers-Danlos syndrome, dermatosparaxis type.

IL-1a is a strong positive regulator of ADAMTS-2 and ADAMTS-3 expression.
Title: Induction of human ADAMTS-2 gene expression by IL-1? is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells.

Data indicate that ADAMTS2 and 3 cleave the amino-propeptide of fibrillar collagens and regulate blood vessels homeostasis and lymphangiogenesis. Also, ADAMTS2 deficiency leads to the dermatosparactic type of Ehlers-Danlos syndrome. [review]
Title: The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.

Pathway inhibition studies revealed that ADAMTS-2 upregulation by IL-6 was mediated by JNK pathway.
Title: IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway.

ADAMTS2 was significantly overexpressed in Fibrous dysplasia (FD) tissues, but rarely expressed in normal bone tissues, suggesting that ADAMTS2 could be a potential biomarker for FD
Title: Gene expression profiling of craniofacial fibrous dysplasia reveals ADAMTS2 overexpression as a potential marker.

The following ADAMTS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAMTS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00230	NM_021599.4 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$239.50-$335.30 $479.00
OHu21699	NM_014244.5 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$609.50-$853.30 $1219.00
OHu96199	XM_017010063.1 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
View Old Accession Versions >>
OHu00230	NM_021599.3	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$239.50-$335.30 $479.00
OHu00230	NM_021599.2	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 2 (ADAMTS2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$239.50-$335.30 $479.00
OHu21699	NM_014244.4	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$609.50-$853.30 $1219.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAMTS2 ( NM_021599.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_067610.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu00230
Clone ID Related Accession (Same CDS sequence)	NM_021599.3 , NM_021599.4 , NM_021599.2
Accession Version	NM_021599.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308213.1, AC109479.3, AC010216.8 and BM512469.1. On Feb 24, 2016 this sequence version replaced NM_021599.2. Transcript Variant: This variant (2) lacks several exons and includes an alternate exon in the 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1. Isoform 2 lacks the TSP type-1 domains compared to isoform 1 but may undergo proteolytic processing similar to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK308213.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGT TCAGGCCGGG CGCGGTGGCT CATGCCTGTT ATCCCAGCAC TTTGGGAGGC 
CAAGGTAGGT GGATCGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067610.1
CDS	103..1803
Translation	MDPPAGAARRLLCPALLLLLLLLPPPLLPPPPPPANARLAAAADPPGGPLGHGAERILAVPVRTDAQGRLVSHVVSAATSRAGVRARRAAPVRTPSFPGGNEEEPGSHLFYNVTVFGRDLHLRLRPNARLVAPGATMEWQGEKGTTRVEPLLGSCLYVGDVAGLAEASSVALSNCDGLAGLIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGPQALDTGASLDSLDSLSRALGVLEEHANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDWPALPQLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKFRPGAVAHACYPSTLGGQGRWIA

Target ORF information:

RefSeq Version	NM_021599.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021599.3

ORF Insert Sequence:

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGT TCAGGCCGGG CGCGGTGGCT CATGCCTGTT ATCCCAGCAC TTTGGGAGGC 
CAAGGTAGGT GGATCGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS2 ( NM_021599.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_067610.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu00230
Clone ID Related Accession (Same CDS sequence)	NM_021599.3 , NM_021599.4 , NM_021599.2
Accession Version	NM_021599.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC109479.3, AK308213.1, AC010216.8 and BM512469.1. On May 31, 2019 this sequence version replaced NM_021599.3. Transcript Variant: This variant (2) lacks several exons and includes an alternate exon in the 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1. Isoform 2 lacks the TSP type-1 domains compared to isoform 1 but may undergo proteolytic processing similar to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK308213.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGT TCAGGCCGGG CGCGGTGGCT CATGCCTGTT ATCCCAGCAC TTTGGGAGGC 
CAAGGTAGGT GGATCGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067610.1
CDS	134..1834
Translation	MDPPAGAARRLLCPALLLLLLLLPPPLLPPPPPPANARLAAAADPPGGPLGHGAERILAVPVRTDAQGRLVSHVVSAATSRAGVRARRAAPVRTPSFPGGNEEEPGSHLFYNVTVFGRDLHLRLRPNARLVAPGATMEWQGEKGTTRVEPLLGSCLYVGDVAGLAEASSVALSNCDGLAGLIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGPQALDTGASLDSLDSLSRALGVLEEHANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDWPALPQLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKFRPGAVAHACYPSTLGGQGRWIA

Target ORF information:

RefSeq Version	NM_021599.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021599.4

ORF Insert Sequence:

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGT TCAGGCCGGG CGCGGTGGCT CATGCCTGTT ATCCCAGCAC TTTGGGAGGC 
CAAGGTAGGT GGATCGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS2 ( NM_021599.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_067610.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 2 (ADAMTS2), transcript variant 2, mRNA.

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CloneID	OHu00230
Clone ID Related Accession (Same CDS sequence)	NM_021599.3 , NM_021599.4 , NM_021599.2
Accession Version	NM_021599.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 2 preproprotein
Comment

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGT TCAGGCCGGG CGCGGTGGCT CATGCCTGTT ATCCCAGCAC TTTGGGAGGC 
CAAGGTAGGT GGATCGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_067610.1

Translation

MDPPAGAARRLLCPALLLLLLLLPPPLLPPPPPPANARLAAAADPPGGPLGHGAERILAVPVRTDAQGRLVSHVVSAATSRAGVRARRAAPVRTPSFPGGNEEEPGSHLFYNVTVFGRDLHLRLRPNARLVAPGATMEWQGEKGTTRVEPLLGSCLYVGDVAGLAEASSVALSNCDGLAGLIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGPQALDTGASLDSLDSLSRALGVLEEHANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDWPALPQLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKFRPGAVAHACYPSTLGGQGRWIA

Target ORF information:

RefSeq Version	NM_021599.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 2 (ADAMTS2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021599.2

ORF Insert Sequence:

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGT TCAGGCCGGG CGCGGTGGCT CATGCCTGTT ATCCCAGCAC TTTGGGAGGC 
CAAGGTAGGT GGATCGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS2 ( NM_014244.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055059.2 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 1, mRNA.

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CloneID	OHu21699
Clone ID Related Accession (Same CDS sequence)	NM_014244.4 , NM_014244.5
Accession Version	NM_014244.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA928965.1, AJ003125.1, AC008544.7, AC010216.8 and CA445758.1. This sequence is a reference standard in the RefSeqGene project. On Jul 23, 2010 this sequence version replaced NM_014244.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ003125.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGC ATTGTTTTAA AGGACACTGC ATCTGGCTGA CACCTGACAT CCTCAAACGG 
GACGGCAGCT GGGGCGCTTG GAGTCCGTTT GGCTCCTGCT CACGTACCTG TGGCACGGGC 
GTGAAGTTCA GGACCCGCCA GTGTGACAAC CCACACCCGG CCAACGGGGG CCGCACCTGC 
TCGGGCCTTG CCTACGACTT CCAGCTCTGC AGCCGCCAGG ACTGCCCCGA CTCCCTGGCT 
GACTTCCGCG AGGAGCAGTG CCGCCAGTGG GACCTGTACT TCGAGCACGG CGACGCCCAG 
CACCACTGGC TGCCCCACGA GCACCGGGAT GCCAAGGAGA GATGCCACCT GTACTGCGAG 
TCCAGGGAGA CCGGGGAGGT GGTGTCCATG AAGCGCATGG TGCATGACGG GACGCGCTGC 
TCCTACAAGG ACGCCTTCAG CCTCTGTGTG CGCGGGGACT GCAGGAAGGT GGGCTGTGAC 
GGTGTGATCG GCTCCAGCAA GCAGGAAGAC AAGTGTGGCG TGTGCGGAGG GGACAACAGC 
CACTGCAAAG TGGTCAAGGG CACGTTCACA CGGTCACCCA AGAAGCATGG TTACATCAAG 
ATGTTTGAGA TCCCTGCAGG AGCCAGACAC CTGCTCATTC AGGAGGTAGA CGCCACCAGC 
CACCATCTGG CCGTCAAGAA CCTGGAGACA GGCAAGTTCA TCTTAAATGA AGAGAATGAC 
GTGGATGCCA GTTCCAAAAC CTTCATTGCC ATGGGCGTGG AGTGGGAGTA CAGAGACGAG 
GACGGCCGGG AGACGCTGCA GACCATGGGC CCCCTCCACG GCACCATCAC CGTTCTGGTC 
ATCCCGGTGG GAGACACCCG GGTCTCACTG ACGTACAAAT ACATGATCCA TGAGGACTCA 
CTGAATGTCG ACGACAACAA CGTCCTGGAA GAGGACTCTG TGGTCTACGA GTGGGCCCTG 
AAGAAGTGGT CTCCGTGCTC CAAGCCCTGT GGCGGAGGGT CCCAGTTCAC CAAGTATGGC 
TGCCGCCGGA GGCTGGACCA CAAGATGGTA CACCGTGGCT TCTGTGCCGC CCTCTCGAAG 
CCCAAAGCCA TCCGCAGAGC GTGCAACCCA CAGGAATGCT CCCAGCCAGT GTGGGTCACA 
GGCGAATGGG AGCCATGTAG CCAGACCTGT GGGCGGACAG GCATGCAGGT GCGCTCCGTG 
CGCTGCATTC AGCCGCTACA CGACAACACC ACCCGCTCCG TGCACGCCAA GCACTGCAAT 
GACGCCCGGC CCGAGAGCCG CCGGGCCTGC AGCCGCGAGC TCTGCCCTGG TCGTTGGCGA 
GCCGGGCCCT GGTCCCAGTG CTCAGTAACC TGTGGCAACG GCACCCAGGA GCGGCCAGTG 
CTCTGCCGCA CCGCGGACGA CAGCTTCGGC ATCTGCCAGG AGGAGCGTCC TGAGACAGCG 
AGGACCTGCA GGCTTGGCCC CTGTCCCCGA AACATCTCAG ATCCCTCCAA GAAGAGCTAC 
GTAGTTCAGT GGCTGTCCCG CCCGGACCCC GACTCGCCCA TCCGGAAGAT CTCGTCAAAG 
GGCCACTGCC AAGGCGACAA GTCAATATTC TGTAGGATGG AAGTCTTGTC CCGCTATTGC 
TCCATCCCAG GCTACAACAA GCTGTGCTGC AAGTCCTGTA ACCTGTACAA CAACCTCACC 
AACGTGGAGG GCAGGATAGA GCCACCGCCT GGGAAGCACA ACGACATTGA CGTGTTCATG 
CCTACCCTCC CAGTGCCCAC TGTAGCCATG GAGGTGCGGC CATCACCAAG CACCCCCCTG 
GAGGTCCCTC TCAATGCCTC CAGCACCAAT GCCACAGAGG ATCACCCAGA AACCAATGCC 
GTAGATGAAC CCTACAAAAT CCATGGCCTG GAAGATGAAG TCCAGCCACC CAACCTAATC 
CCTCGACGAC CGAGCCCCTA TGAAAAGACC AGAAACCAAA GAATCCAAGA GCTCATTGAT 
GAGATGCGGA AGAAAGAGAT GCTCGGAAAG TTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055059.2
CDS	103..3738
Translation	MDPPAGAARRLLCPALLLLLLLLPPPLLPPPPPPANARLAAAADPPGGPLGHGAERILAVPVRTDAQGRLVSHVVSAATSRAGVRARRAAPVRTPSFPGGNEEEPGSHLFYNVTVFGRDLHLRLRPNARLVAPGATMEWQGEKGTTRVEPLLGSCLYVGDVAGLAEASSVALSNCDGLAGLIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGPQALDTGASLDSLDSLSRALGVLEEHANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDWPALPQLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKHCFKGHCIWLTPDILKRDGSWGAWSPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYDFQLCSRQDCPDSLADFREEQCRQWDLYFEHGDAQHHWLPHEHRDAKERCHLYCESRETGEVVSMKRMVHDGTRCSYKDAFSLCVRGDCRKVGCDGVIGSSKQEDKCGVCGGDNSHCKVVKGTFTRSPKKHGYIKMFEIPAGARHLLIQEVDATSHHLAVKNLETGKFILNEENDVDASSKTFIAMGVEWEYRDEDGRETLQTMGPLHGTITVLVIPVGDTRVSLTYKYMIHEDSLNVDDNNVLEEDSVVYEWALKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVHRGFCAALSKPKAIRRACNPQECSQPVWVTGEWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHCNDARPESRRACSRELCPGRWRAGPWSQCSVTCGNGTQERPVLCRTADDSFGICQEERPETARTCRLGPCPRNISDPSKKSYVVQWLSRPDPDSPIRKISSKGHCQGDKSIFCRMEVLSRYCSIPGYNKLCCKSCNLYNNLTNVEGRIEPPPGKHNDIDVFMPTLPVPTVAMEVRPSPSTPLEVPLNASSTNATEDHPETNAVDEPYKIHGLEDEVQPPNLIPRRPSPYEKTRNQRIQELIDEMRKKEMLGKF

Target ORF information:

RefSeq Version	NM_014244.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014244.4

ORF Insert Sequence:

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGC ATTGTTTTAA AGGACACTGC ATCTGGCTGA CACCTGACAT CCTCAAACGG 
GACGGCAGCT GGGGCGCTTG GAGTCCGTTT GGCTCCTGCT CACGTACCTG TGGCACGGGC 
GTGAAGTTCA GGACCCGCCA GTGTGACAAC CCACACCCGG CCAACGGGGG CCGCACCTGC 
TCGGGCCTTG CCTACGACTT CCAGCTCTGC AGCCGCCAGG ACTGCCCCGA CTCCCTGGCT 
GACTTCCGCG AGGAGCAGTG CCGCCAGTGG GACCTGTACT TCGAGCACGG CGACGCCCAG 
CACCACTGGC TGCCCCACGA GCACCGGGAT GCCAAGGAGA GATGCCACCT GTACTGCGAG 
TCCAGGGAGA CCGGGGAGGT GGTGTCCATG AAGCGCATGG TGCATGACGG GACGCGCTGC 
TCCTACAAGG ACGCCTTCAG CCTCTGTGTG CGCGGGGACT GCAGGAAGGT GGGCTGTGAC 
GGTGTGATCG GCTCCAGCAA GCAGGAAGAC AAGTGTGGCG TGTGCGGAGG GGACAACAGC 
CACTGCAAAG TGGTCAAGGG CACGTTCACA CGGTCACCCA AGAAGCATGG TTACATCAAG 
ATGTTTGAGA TCCCTGCAGG AGCCAGACAC CTGCTCATTC AGGAGGTAGA CGCCACCAGC 
CACCATCTGG CCGTCAAGAA CCTGGAGACA GGCAAGTTCA TCTTAAATGA AGAGAATGAC 
GTGGATGCCA GTTCCAAAAC CTTCATTGCC ATGGGCGTGG AGTGGGAGTA CAGAGACGAG 
GACGGCCGGG AGACGCTGCA GACCATGGGC CCCCTCCACG GCACCATCAC CGTTCTGGTC 
ATCCCGGTGG GAGACACCCG GGTCTCACTG ACGTACAAAT ACATGATCCA TGAGGACTCA 
CTGAATGTCG ACGACAACAA CGTCCTGGAA GAGGACTCTG TGGTCTACGA GTGGGCCCTG 
AAGAAGTGGT CTCCGTGCTC CAAGCCCTGT GGCGGAGGGT CCCAGTTCAC CAAGTATGGC 
TGCCGCCGGA GGCTGGACCA CAAGATGGTA CACCGTGGCT TCTGTGCCGC CCTCTCGAAG 
CCCAAAGCCA TCCGCAGAGC GTGCAACCCA CAGGAATGCT CCCAGCCAGT GTGGGTCACA 
GGCGAATGGG AGCCATGTAG CCAGACCTGT GGGCGGACAG GCATGCAGGT GCGCTCCGTG 
CGCTGCATTC AGCCGCTACA CGACAACACC ACCCGCTCCG TGCACGCCAA GCACTGCAAT 
GACGCCCGGC CCGAGAGCCG CCGGGCCTGC AGCCGCGAGC TCTGCCCTGG TCGTTGGCGA 
GCCGGGCCCT GGTCCCAGTG CTCAGTAACC TGTGGCAACG GCACCCAGGA GCGGCCAGTG 
CTCTGCCGCA CCGCGGACGA CAGCTTCGGC ATCTGCCAGG AGGAGCGTCC TGAGACAGCG 
AGGACCTGCA GGCTTGGCCC CTGTCCCCGA AACATCTCAG ATCCCTCCAA GAAGAGCTAC 
GTAGTTCAGT GGCTGTCCCG CCCGGACCCC GACTCGCCCA TCCGGAAGAT CTCGTCAAAG 
GGCCACTGCC AAGGCGACAA GTCAATATTC TGTAGGATGG AAGTCTTGTC CCGCTATTGC 
TCCATCCCAG GCTACAACAA GCTGTGCTGC AAGTCCTGTA ACCTGTACAA CAACCTCACC 
AACGTGGAGG GCAGGATAGA GCCACCGCCT GGGAAGCACA ACGACATTGA CGTGTTCATG 
CCTACCCTCC CAGTGCCCAC TGTAGCCATG GAGGTGCGGC CATCACCAAG CACCCCCCTG 
GAGGTCCCTC TCAATGCCTC CAGCACCAAT GCCACAGAGG ATCACCCAGA AACCAATGCC 
GTAGATGAAC CCTACAAAAT CCATGGCCTG GAAGATGAAG TCCAGCCACC CAACCTAATC 
CCTCGACGAC CGAGCCCCTA TGAAAAGACC AGAAACCAAA GAATCCAAGA GCTCATTGAT 
GAGATGCGGA AGAAAGAGAT GCTCGGAAAG TTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS2 ( NM_014244.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_055059.2 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21699
Clone ID Related Accession (Same CDS sequence)	NM_014244.4 , NM_014244.5
Accession Version	NM_014244.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC109479.3, DA928965.1, AJ003125.1, AC008544.7, AC010216.8 and CA445758.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_014244.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ003125.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000251582.12/ ENSP00000251582.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGC ATTGTTTTAA AGGACACTGC ATCTGGCTGA CACCTGACAT CCTCAAACGG 
GACGGCAGCT GGGGCGCTTG GAGTCCGTTT GGCTCCTGCT CACGTACCTG TGGCACGGGC 
GTGAAGTTCA GGACCCGCCA GTGTGACAAC CCACACCCGG CCAACGGGGG CCGCACCTGC 
TCGGGCCTTG CCTACGACTT CCAGCTCTGC AGCCGCCAGG ACTGCCCCGA CTCCCTGGCT 
GACTTCCGCG AGGAGCAGTG CCGCCAGTGG GACCTGTACT TCGAGCACGG CGACGCCCAG 
CACCACTGGC TGCCCCACGA GCACCGGGAT GCCAAGGAGA GATGCCACCT GTACTGCGAG 
TCCAGGGAGA CCGGGGAGGT GGTGTCCATG AAGCGCATGG TGCATGACGG GACGCGCTGC 
TCCTACAAGG ACGCCTTCAG CCTCTGTGTG CGCGGGGACT GCAGGAAGGT GGGCTGTGAC 
GGTGTGATCG GCTCCAGCAA GCAGGAAGAC AAGTGTGGCG TGTGCGGAGG GGACAACAGC 
CACTGCAAAG TGGTCAAGGG CACGTTCACA CGGTCACCCA AGAAGCATGG TTACATCAAG 
ATGTTTGAGA TCCCTGCAGG AGCCAGACAC CTGCTCATTC AGGAGGTAGA CGCCACCAGC 
CACCATCTGG CCGTCAAGAA CCTGGAGACA GGCAAGTTCA TCTTAAATGA AGAGAATGAC 
GTGGATGCCA GTTCCAAAAC CTTCATTGCC ATGGGCGTGG AGTGGGAGTA CAGAGACGAG 
GACGGCCGGG AGACGCTGCA GACCATGGGC CCCCTCCACG GCACCATCAC CGTTCTGGTC 
ATCCCGGTGG GAGACACCCG GGTCTCACTG ACGTACAAAT ACATGATCCA TGAGGACTCA 
CTGAATGTCG ACGACAACAA CGTCCTGGAA GAGGACTCTG TGGTCTACGA GTGGGCCCTG 
AAGAAGTGGT CTCCGTGCTC CAAGCCCTGT GGCGGAGGGT CCCAGTTCAC CAAGTATGGC 
TGCCGCCGGA GGCTGGACCA CAAGATGGTA CACCGTGGCT TCTGTGCCGC CCTCTCGAAG 
CCCAAAGCCA TCCGCAGAGC GTGCAACCCA CAGGAATGCT CCCAGCCAGT GTGGGTCACA 
GGCGAATGGG AGCCATGTAG CCAGACCTGT GGGCGGACAG GCATGCAGGT GCGCTCCGTG 
CGCTGCATTC AGCCGCTACA CGACAACACC ACCCGCTCCG TGCACGCCAA GCACTGCAAT 
GACGCCCGGC CCGAGAGCCG CCGGGCCTGC AGCCGCGAGC TCTGCCCTGG TCGTTGGCGA 
GCCGGGCCCT GGTCCCAGTG CTCAGTAACC TGTGGCAACG GCACCCAGGA GCGGCCAGTG 
CTCTGCCGCA CCGCGGACGA CAGCTTCGGC ATCTGCCAGG AGGAGCGTCC TGAGACAGCG 
AGGACCTGCA GGCTTGGCCC CTGTCCCCGA AACATCTCAG ATCCCTCCAA GAAGAGCTAC 
GTAGTTCAGT GGCTGTCCCG CCCGGACCCC GACTCGCCCA TCCGGAAGAT CTCGTCAAAG 
GGCCACTGCC AAGGCGACAA GTCAATATTC TGTAGGATGG AAGTCTTGTC CCGCTATTGC 
TCCATCCCAG GCTACAACAA GCTGTGCTGC AAGTCCTGTA ACCTGTACAA CAACCTCACC 
AACGTGGAGG GCAGGATAGA GCCACCGCCT GGGAAGCACA ACGACATTGA CGTGTTCATG 
CCTACCCTCC CAGTGCCCAC TGTAGCCATG GAGGTGCGGC CATCACCAAG CACCCCCCTG 
GAGGTCCCTC TCAATGCCTC CAGCACCAAT GCCACAGAGG ATCACCCAGA AACCAATGCC 
GTAGATGAAC CCTACAAAAT CCATGGCCTG GAAGATGAAG TCCAGCCACC CAACCTAATC 
CCTCGACGAC CGAGCCCCTA TGAAAAGACC AGAAACCAAA GAATCCAAGA GCTCATTGAT 
GAGATGCGGA AGAAAGAGAT GCTCGGAAAG TTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055059.2
CDS	134..3769
Translation	MDPPAGAARRLLCPALLLLLLLLPPPLLPPPPPPANARLAAAADPPGGPLGHGAERILAVPVRTDAQGRLVSHVVSAATSRAGVRARRAAPVRTPSFPGGNEEEPGSHLFYNVTVFGRDLHLRLRPNARLVAPGATMEWQGEKGTTRVEPLLGSCLYVGDVAGLAEASSVALSNCDGLAGLIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGPQALDTGASLDSLDSLSRALGVLEEHANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDWPALPQLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKHCFKGHCIWLTPDILKRDGSWGAWSPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYDFQLCSRQDCPDSLADFREEQCRQWDLYFEHGDAQHHWLPHEHRDAKERCHLYCESRETGEVVSMKRMVHDGTRCSYKDAFSLCVRGDCRKVGCDGVIGSSKQEDKCGVCGGDNSHCKVVKGTFTRSPKKHGYIKMFEIPAGARHLLIQEVDATSHHLAVKNLETGKFILNEENDVDASSKTFIAMGVEWEYRDEDGRETLQTMGPLHGTITVLVIPVGDTRVSLTYKYMIHEDSLNVDDNNVLEEDSVVYEWALKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVHRGFCAALSKPKAIRRACNPQECSQPVWVTGEWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHCNDARPESRRACSRELCPGRWRAGPWSQCSVTCGNGTQERPVLCRTADDSFGICQEERPETARTCRLGPCPRNISDPSKKSYVVQWLSRPDPDSPIRKISSKGHCQGDKSIFCRMEVLSRYCSIPGYNKLCCKSCNLYNNLTNVEGRIEPPPGKHNDIDVFMPTLPVPTVAMEVRPSPSTPLEVPLNASSTNATEDHPETNAVDEPYKIHGLEDEVQPPNLIPRRPSPYEKTRNQRIQELIDEMRKKEMLGKF

Target ORF information:

RefSeq Version	NM_014244.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014244.5

ORF Insert Sequence:

ATGGATCCGC CGGCGGGAGC CGCTCGCCGC CTGCTCTGCC CCGCGCTGCT GCTGCTGCTG 
CTGCTGCTGC CGCCGCCGCT CCTGCCGCCG CCGCCGCCGC CCGCGAACGC CAGGCTCGCC 
GCCGCCGCCG ACCCCCCAGG CGGGCCCCTG GGGCACGGAG CGGAGCGCAT CCTGGCGGTG 
CCCGTGCGCA CTGACGCCCA GGGCCGCTTG GTGTCCCACG TGGTGTCGGC AGCTACGTCC 
AGAGCAGGGG TACGAGCCCG CAGGGCCGCC CCGGTCCGGA CCCCGAGCTT CCCCGGAGGC 
AACGAGGAGG AGCCTGGCAG TCACCTCTTC TACAATGTCA CGGTCTTTGG CCGAGACCTG 
CACCTGCGGC TGCGGCCCAA CGCCCGCCTC GTGGCGCCCG GGGCCACTAT GGAGTGGCAG 
GGCGAGAAGG GCACCACCCG CGTGGAGCCC CTGCTCGGGA GCTGTCTCTA CGTCGGAGAC 
GTGGCCGGCC TAGCCGAAGC CTCCTCTGTG GCGCTCAGCA ACTGCGATGG GCTGGCTGGT 
CTGATCCGGA TGGAGGAGGA GGAGTTCTTC ATCGAACCCT TGGAGAAGGG GCTGGCGGCG 
CAGGAGGCTG AGCAAGGCCG TGTGCATGTG GTGTATCGCC GGCCACCCAC GTCCCCTCCT 
CTCGGGGGGC CACAGGCCCT GGACACAGGG GCCTCCCTGG ACAGCCTGGA CAGCCTCAGC 
CGCGCCCTGG GCGTCCTAGA GGAGCACGCC AACAGCTCGA GGCGGAGGGC ACGCAGGCAT 
GCTGCGGACG ATGACTACAA CATCGAGGTC CTGCTGGGCG TGGATGACTC TGTGGTGCAG 
TTCCACGGGA AGGAGCACGT ACAGAAGTAC CTGCTGACAC TCATGAACAT TGTCAATGAA 
ATCTACCATG ACGAGTCCTT GGGTGCCCAC ATCAACGTGG TCCTGGTGCG GATCATCCTC 
CTGAGCTATG GAAAGTCCAT GAGCCTCATC GAGATCGGGA ACCCCTCTCA GAGCCTGGAG 
AATGTCTGCC GCTGGGCCTA CCTCCAGCAG AAGCCAGACA CGGGCCACGA TGAATACCAC 
GATCACGCCA TCTTCCTCAC ACGGCAGGAC TTTGGGCCTT CCGGCATGCA AGGCTATGCT 
CCTGTCACCG GCATGTGCCA TCCGGTCCGC AGCTGCACCC TGAACCATGA GGACGGCTTC 
TCCTCAGCGT TTGTGGTGGC CCATGAGACT GGCCACGTGC TGGGCATGGA GCACGACGGG 
CAGGGCAACC GCTGTGGCGA CGAGGTGCGG CTGGGCAGCA TCATGGCGCC CCTGGTGCAG 
GCCGCCTTCC ACCGCTTCCA CTGGTCCCGC TGCAGCCAGC AGGAGCTGAG CCGCTACCTG 
CACTCCTATG ACTGCCTGCT GGATGACCCC TTCGCCCACG ACTGGCCGGC GCTGCCCCAG 
CTCCCGGGAC TGCACTACTC CATGAACGAG CAATGCCGCT TTGACTTCGG CCTGGGCTAC 
ATGATGTGCA CGGCGTTCCG GACCTTTGAC CCCTGCAAGC AGCTGTGGTG CAGCCATCCT 
GACAACCCCT ACTTTTGCAA GACCAAGAAG GGGCCCCCCT TGGACGGGAC TATGTGTGCA 
CCTGGCAAGC ATTGTTTTAA AGGACACTGC ATCTGGCTGA CACCTGACAT CCTCAAACGG 
GACGGCAGCT GGGGCGCTTG GAGTCCGTTT GGCTCCTGCT CACGTACCTG TGGCACGGGC 
GTGAAGTTCA GGACCCGCCA GTGTGACAAC CCACACCCGG CCAACGGGGG CCGCACCTGC 
TCGGGCCTTG CCTACGACTT CCAGCTCTGC AGCCGCCAGG ACTGCCCCGA CTCCCTGGCT 
GACTTCCGCG AGGAGCAGTG CCGCCAGTGG GACCTGTACT TCGAGCACGG CGACGCCCAG 
CACCACTGGC TGCCCCACGA GCACCGGGAT GCCAAGGAGA GATGCCACCT GTACTGCGAG 
TCCAGGGAGA CCGGGGAGGT GGTGTCCATG AAGCGCATGG TGCATGACGG GACGCGCTGC 
TCCTACAAGG ACGCCTTCAG CCTCTGTGTG CGCGGGGACT GCAGGAAGGT GGGCTGTGAC 
GGTGTGATCG GCTCCAGCAA GCAGGAAGAC AAGTGTGGCG TGTGCGGAGG GGACAACAGC 
CACTGCAAAG TGGTCAAGGG CACGTTCACA CGGTCACCCA AGAAGCATGG TTACATCAAG 
ATGTTTGAGA TCCCTGCAGG AGCCAGACAC CTGCTCATTC AGGAGGTAGA CGCCACCAGC 
CACCATCTGG CCGTCAAGAA CCTGGAGACA GGCAAGTTCA TCTTAAATGA AGAGAATGAC 
GTGGATGCCA GTTCCAAAAC CTTCATTGCC ATGGGCGTGG AGTGGGAGTA CAGAGACGAG 
GACGGCCGGG AGACGCTGCA GACCATGGGC CCCCTCCACG GCACCATCAC CGTTCTGGTC 
ATCCCGGTGG GAGACACCCG GGTCTCACTG ACGTACAAAT ACATGATCCA TGAGGACTCA 
CTGAATGTCG ACGACAACAA CGTCCTGGAA GAGGACTCTG TGGTCTACGA GTGGGCCCTG 
AAGAAGTGGT CTCCGTGCTC CAAGCCCTGT GGCGGAGGGT CCCAGTTCAC CAAGTATGGC 
TGCCGCCGGA GGCTGGACCA CAAGATGGTA CACCGTGGCT TCTGTGCCGC CCTCTCGAAG 
CCCAAAGCCA TCCGCAGAGC GTGCAACCCA CAGGAATGCT CCCAGCCAGT GTGGGTCACA 
GGCGAATGGG AGCCATGTAG CCAGACCTGT GGGCGGACAG GCATGCAGGT GCGCTCCGTG 
CGCTGCATTC AGCCGCTACA CGACAACACC ACCCGCTCCG TGCACGCCAA GCACTGCAAT 
GACGCCCGGC CCGAGAGCCG CCGGGCCTGC AGCCGCGAGC TCTGCCCTGG TCGTTGGCGA 
GCCGGGCCCT GGTCCCAGTG CTCAGTAACC TGTGGCAACG GCACCCAGGA GCGGCCAGTG 
CTCTGCCGCA CCGCGGACGA CAGCTTCGGC ATCTGCCAGG AGGAGCGTCC TGAGACAGCG 
AGGACCTGCA GGCTTGGCCC CTGTCCCCGA AACATCTCAG ATCCCTCCAA GAAGAGCTAC 
GTAGTTCAGT GGCTGTCCCG CCCGGACCCC GACTCGCCCA TCCGGAAGAT CTCGTCAAAG 
GGCCACTGCC AAGGCGACAA GTCAATATTC TGTAGGATGG AAGTCTTGTC CCGCTATTGC 
TCCATCCCAG GCTACAACAA GCTGTGCTGC AAGTCCTGTA ACCTGTACAA CAACCTCACC 
AACGTGGAGG GCAGGATAGA GCCACCGCCT GGGAAGCACA ACGACATTGA CGTGTTCATG 
CCTACCCTCC CAGTGCCCAC TGTAGCCATG GAGGTGCGGC CATCACCAAG CACCCCCCTG 
GAGGTCCCTC TCAATGCCTC CAGCACCAAT GCCACAGAGG ATCACCCAGA AACCAATGCC 
GTAGATGAAC CCTACAAAAT CCATGGCCTG GAAGATGAAG TCCAGCCACC CAACCTAATC 
CCTCGACGAC CGAGCCCCTA TGAAAAGACC AGAAACCAAA GAATCCAAGA GCTCATTGAT 
GAGATGCGGA AGAAAGAGAT GCTCGGAAAG TTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS2 ( XM_017010063.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865552.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant X1, mRNA.

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CloneID	OHu96199
Clone ID Related Accession (Same CDS sequence)	XM_017010063.1
Accession Version	XM_017010063.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3141bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTGGAC CTGATGGTGC CAGCAGGCTG GATGGCAGGG CTGGTCTGAT CCGGATGGAG 
GAGGAGGAGT TCTTCATCGA ACCCTTGGAG AAGGGGCTGG CGGCGCAGGA GGCTGAGCAA 
GGCCGTGTGC ATGTGGTGTA TCGCCGGCCA CCCACGTCCC CTCCTCTCGG GGGGCCACAG 
GCCCTGGACA CAGGGGCCTC CCTGGACAGC CTGGACAGCC TCAGCCGCGC CCTGGGCGTC 
CTAGAGGAGC ACGCCAACAG CTCGAGGCGG AGGGCACGCA GGCATGCTGC GGACGATGAC 
TACAACATCG AGGTCCTGCT GGGCGTGGAT GACTCTGTGG TGCAGTTCCA CGGGAAGGAG 
CACGTACAGA AGTACCTGCT GACACTCATG AACATTGTCA ATGAAATCTA CCATGACGAG 
TCCTTGGGTG CCCACATCAA CGTGGTCCTG GTGCGGATCA TCCTCCTGAG CTATGGAAAG 
TCCATGAGCC TCATCGAGAT CGGGAACCCC TCTCAGAGCC TGGAGAATGT CTGCCGCTGG 
GCCTACCTCC AGCAGAAGCC AGACACGGGC CACGATGAAT ACCACGATCA CGCCATCTTC 
CTCACACGGC AGGACTTTGG GCCTTCCGGC ATGCAAGGCT ATGCTCCTGT CACCGGCATG 
TGCCATCCGG TCCGCAGCTG CACCCTGAAC CATGAGGACG GCTTCTCCTC AGCGTTTGTG 
GTGGCCCATG AGACTGGCCA CGTGCTGGGC ATGGAGCACG ACGGGCAGGG CAACCGCTGT 
GGCGACGAGG TGCGGCTGGG CAGCATCATG GCGCCCCTGG TGCAGGCCGC CTTCCACCGC 
TTCCACTGGT CCCGCTGCAG CCAGCAGGAG CTGAGCCGCT ACCTGCACTC CTATGACTGC 
CTGCTGGATG ACCCCTTCGC CCACGACTGG CCGGCGCTGC CCCAGCTCCC GGGACTGCAC 
TACTCCATGA ACGAGCAATG CCGCTTTGAC TTCGGCCTGG GCTACATGAT GTGCACGGCG 
TTCCGGACCT TTGACCCCTG CAAGCAGCTG TGGTGCAGCC ATCCTGACAA CCCCTACTTT 
TGCAAGACCA AGAAGGGGCC CCCCTTGGAC GGGACTATGT GTGCACCTGG CAAGCATTGT 
TTTAAAGGAC ACTGCATCTG GCTGACACCT GACATCCTCA AACGGGACGG CAGCTGGGGC 
GCTTGGAGTC CGTTTGGCTC CTGCTCACGT ACCTGTGGCA CGGGCGTGAA GTTCAGGACC 
CGCCAGTGTG ACAACCCACA CCCGGCCAAC GGGGGCCGCA CCTGCTCGGG CCTTGCCTAC 
GACTTCCAGC TCTGCAGCCG CCAGGACTGC CCCGACTCCC TGGCTGACTT CCGCGAGGAG 
CAGTGCCGCC AGTGGGACCT GTACTTCGAG CACGGCGACG CCCAGCACCA CTGGCTGCCC 
CACGAGCACC GGGATGCCAA GGAGAGATGC CACCTGTACT GCGAGTCCAG GGAGACCGGG 
GAGGTGGTGT CCATGAAGCG CATGGTGCAT GACGGGACGC GCTGCTCCTA CAAGGACGCC 
TTCAGCCTCT GTGTGCGCGG GGACTGCAGG AAGGTGGGCT GTGACGGTGT GATCGGCTCC 
AGCAAGCAGG AAGACAAGTG TGGCGTGTGC GGAGGGGACA ACAGCCACTG CAAAGTGGTC 
AAGGGCACGT TCACACGGTC ACCCAAGAAG CATGGTTACA TCAAGATGTT TGAGATCCCT 
GCAGGAGCCA GACACCTGCT CATTCAGGAG GTAGACGCCA CCAGCCACCA TCTGGCCGTC 
AAGAACCTGG AGACAGGCAA GTTCATCTTA AATGAAGAGA ATGACGTGGA TGCCAGTTCC 
AAAACCTTCA TTGCCATGGG CGTGGAGTGG GAGTACAGAG ACGAGGACGG CCGGGAGACG 
CTGCAGACCA TGGGCCCCCT CCACGGCACC ATCACCGTTC TGGTCATCCC GGTGGGAGAC 
ACCCGGGTCT CACTGACGTA CAAATACATG ATCCATGAGG ACTCACTGAA TGTCGACGAC 
AACAACGTCC TGGAAGAGGA CTCTGTGGTC TACGAGTGGG CCCTGAAGAA GTGGTCTCCG 
TGCTCCAAGC CCTGTGGCGG AGGGTCCCAG TTCACCAAGT ATGGCTGCCG CCGGAGGCTG 
GACCACAAGA TGGTACACCG TGGCTTCTGT GCCGCCCTCT CGAAGCCCAA AGCCATCCGC 
AGAGCGTGCA ACCCACAGGA ATGCTCCCAG CCAGTGTGGG TCACAGGCGA ATGGGAGCCA 
TGTAGCCAGA CCTGTGGGCG GACAGGCATG CAGGTGCGCT CCGTGCGCTG CATTCAGCCG 
CTACACGACA ACACCACCCG CTCCGTGCAC GCCAAGCACT GCAATGACGC CCGGCCCGAG 
AGCCGCCGGG CCTGCAGCCG CGAGCTCTGC CCTGGTCGTT GGCGAGCCGG GCCCTGGTCC 
CAGTGCTCAG TAACCTGTGG CAACGGCACC CAGGAGCGGC CAGTGCTCTG CCGCACCGCG 
GACGACAGCT TCGGCATCTG CCAGGAGGAG CGTCCTGAGA CAGCGAGGAC CTGCAGGCTT 
GGCCCCTGTC CCCGAAACAT CTCAGATCCC TCCAAGAAGA GCTACGTAGT TCAGTGGCTG 
TCCCGCCCGG ACCCCGACTC GCCCATCCGG AAGATCTCGT CAAAGGGCCA CTGCCAAGGC 
GACAAGTCAA TATTCTGTAG GATGGAAGTC TTGTCCCGCT ATTGCTCCAT CCCAGGCTAC 
AACAAGCTGT GCTGCAAGTC CTGTAACCTG TACAACAACC TCACCAACGT GGAGGGCAGG 
ATAGAGCCAC CGCCTGGGAA GCACAACGAC ATTGACGTGT TCATGCCTAC CCTCCCAGTG 
CCCACTGTAG CCATGGAGGT GCGGCCATCA CCAAGCACCC CCCTGGAGGT CCCTCTCAAT 
GCCTCCAGCA CCAATGCCAC AGAGGATCAC CCAGAAACCA ATGCCGTAGA TGAACCCTAC 
AAAATCCATG GCCTGGAAGA TGAAGTCCAG CCACCCAACC TAATCCCTCG ACGACCGAGC 
CCCTATGAAA AGACCAGAAA CCAAAGAATC CAAGAGCTCA TTGATGAGAT GCGGAAGAAA 
GAGATGCTCG GAAAGTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865552.1
CDS	34..3174
Translation	MGGPDGASRLDGRAGLIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGPQALDTGASLDSLDSLSRALGVLEEHANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDWPALPQLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKHCFKGHCIWLTPDILKRDGSWGAWSPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYDFQLCSRQDCPDSLADFREEQCRQWDLYFEHGDAQHHWLPHEHRDAKERCHLYCESRETGEVVSMKRMVHDGTRCSYKDAFSLCVRGDCRKVGCDGVIGSSKQEDKCGVCGGDNSHCKVVKGTFTRSPKKHGYIKMFEIPAGARHLLIQEVDATSHHLAVKNLETGKFILNEENDVDASSKTFIAMGVEWEYRDEDGRETLQTMGPLHGTITVLVIPVGDTRVSLTYKYMIHEDSLNVDDNNVLEEDSVVYEWALKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVHRGFCAALSKPKAIRRACNPQECSQPVWVTGEWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHCNDARPESRRACSRELCPGRWRAGPWSQCSVTCGNGTQERPVLCRTADDSFGICQEERPETARTCRLGPCPRNISDPSKKSYVVQWLSRPDPDSPIRKISSKGHCQGDKSIFCRMEVLSRYCSIPGYNKLCCKSCNLYNNLTNVEGRIEPPPGKHNDIDVFMPTLPVPTVAMEVRPSPSTPLEVPLNASSTNATEDHPETNAVDEPYKIHGLEDEVQPPNLIPRRPSPYEKTRNQRIQELIDEMRKKEMLGKF

Target ORF information:

RefSeq Version	XM_017010063.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010063.1

ORF Insert Sequence:

ATGGGTGGAC CTGATGGTGC CAGCAGGCTG GATGGCAGGG CTGGTCTGAT CCGGATGGAG 
GAGGAGGAGT TCTTCATCGA ACCCTTGGAG AAGGGGCTGG CGGCGCAGGA GGCTGAGCAA 
GGCCGTGTGC ATGTGGTGTA TCGCCGGCCA CCCACGTCCC CTCCTCTCGG GGGGCCACAG 
GCCCTGGACA CAGGGGCCTC CCTGGACAGC CTGGACAGCC TCAGCCGCGC CCTGGGCGTC 
CTAGAGGAGC ACGCCAACAG CTCGAGGCGG AGGGCACGCA GGCATGCTGC GGACGATGAC 
TACAACATCG AGGTCCTGCT GGGCGTGGAT GACTCTGTGG TGCAGTTCCA CGGGAAGGAG 
CACGTACAGA AGTACCTGCT GACACTCATG AACATTGTCA ATGAAATCTA CCATGACGAG 
TCCTTGGGTG CCCACATCAA CGTGGTCCTG GTGCGGATCA TCCTCCTGAG CTATGGAAAG 
TCCATGAGCC TCATCGAGAT CGGGAACCCC TCTCAGAGCC TGGAGAATGT CTGCCGCTGG 
GCCTACCTCC AGCAGAAGCC AGACACGGGC CACGATGAAT ACCACGATCA CGCCATCTTC 
CTCACACGGC AGGACTTTGG GCCTTCCGGC ATGCAAGGCT ATGCTCCTGT CACCGGCATG 
TGCCATCCGG TCCGCAGCTG CACCCTGAAC CATGAGGACG GCTTCTCCTC AGCGTTTGTG 
GTGGCCCATG AGACTGGCCA CGTGCTGGGC ATGGAGCACG ACGGGCAGGG CAACCGCTGT 
GGCGACGAGG TGCGGCTGGG CAGCATCATG GCGCCCCTGG TGCAGGCCGC CTTCCACCGC 
TTCCACTGGT CCCGCTGCAG CCAGCAGGAG CTGAGCCGCT ACCTGCACTC CTATGACTGC 
CTGCTGGATG ACCCCTTCGC CCACGACTGG CCGGCGCTGC CCCAGCTCCC GGGACTGCAC 
TACTCCATGA ACGAGCAATG CCGCTTTGAC TTCGGCCTGG GCTACATGAT GTGCACGGCG 
TTCCGGACCT TTGACCCCTG CAAGCAGCTG TGGTGCAGCC ATCCTGACAA CCCCTACTTT 
TGCAAGACCA AGAAGGGGCC CCCCTTGGAC GGGACTATGT GTGCACCTGG CAAGCATTGT 
TTTAAAGGAC ACTGCATCTG GCTGACACCT GACATCCTCA AACGGGACGG CAGCTGGGGC 
GCTTGGAGTC CGTTTGGCTC CTGCTCACGT ACCTGTGGCA CGGGCGTGAA GTTCAGGACC 
CGCCAGTGTG ACAACCCACA CCCGGCCAAC GGGGGCCGCA CCTGCTCGGG CCTTGCCTAC 
GACTTCCAGC TCTGCAGCCG CCAGGACTGC CCCGACTCCC TGGCTGACTT CCGCGAGGAG 
CAGTGCCGCC AGTGGGACCT GTACTTCGAG CACGGCGACG CCCAGCACCA CTGGCTGCCC 
CACGAGCACC GGGATGCCAA GGAGAGATGC CACCTGTACT GCGAGTCCAG GGAGACCGGG 
GAGGTGGTGT CCATGAAGCG CATGGTGCAT GACGGGACGC GCTGCTCCTA CAAGGACGCC 
TTCAGCCTCT GTGTGCGCGG GGACTGCAGG AAGGTGGGCT GTGACGGTGT GATCGGCTCC 
AGCAAGCAGG AAGACAAGTG TGGCGTGTGC GGAGGGGACA ACAGCCACTG CAAAGTGGTC 
AAGGGCACGT TCACACGGTC ACCCAAGAAG CATGGTTACA TCAAGATGTT TGAGATCCCT 
GCAGGAGCCA GACACCTGCT CATTCAGGAG GTAGACGCCA CCAGCCACCA TCTGGCCGTC 
AAGAACCTGG AGACAGGCAA GTTCATCTTA AATGAAGAGA ATGACGTGGA TGCCAGTTCC 
AAAACCTTCA TTGCCATGGG CGTGGAGTGG GAGTACAGAG ACGAGGACGG CCGGGAGACG 
CTGCAGACCA TGGGCCCCCT CCACGGCACC ATCACCGTTC TGGTCATCCC GGTGGGAGAC 
ACCCGGGTCT CACTGACGTA CAAATACATG ATCCATGAGG ACTCACTGAA TGTCGACGAC 
AACAACGTCC TGGAAGAGGA CTCTGTGGTC TACGAGTGGG CCCTGAAGAA GTGGTCTCCG 
TGCTCCAAGC CCTGTGGCGG AGGGTCCCAG TTCACCAAGT ATGGCTGCCG CCGGAGGCTG 
GACCACAAGA TGGTACACCG TGGCTTCTGT GCCGCCCTCT CGAAGCCCAA AGCCATCCGC 
AGAGCGTGCA ACCCACAGGA ATGCTCCCAG CCAGTGTGGG TCACAGGCGA ATGGGAGCCA 
TGTAGCCAGA CCTGTGGGCG GACAGGCATG CAGGTGCGCT CCGTGCGCTG CATTCAGCCG 
CTACACGACA ACACCACCCG CTCCGTGCAC GCCAAGCACT GCAATGACGC CCGGCCCGAG 
AGCCGCCGGG CCTGCAGCCG CGAGCTCTGC CCTGGTCGTT GGCGAGCCGG GCCCTGGTCC 
CAGTGCTCAG TAACCTGTGG CAACGGCACC CAGGAGCGGC CAGTGCTCTG CCGCACCGCG 
GACGACAGCT TCGGCATCTG CCAGGAGGAG CGTCCTGAGA CAGCGAGGAC CTGCAGGCTT 
GGCCCCTGTC CCCGAAACAT CTCAGATCCC TCCAAGAAGA GCTACGTAGT TCAGTGGCTG 
TCCCGCCCGG ACCCCGACTC GCCCATCCGG AAGATCTCGT CAAAGGGCCA CTGCCAAGGC 
GACAAGTCAA TATTCTGTAG GATGGAAGTC TTGTCCCGCT ATTGCTCCAT CCCAGGCTAC 
AACAAGCTGT GCTGCAAGTC CTGTAACCTG TACAACAACC TCACCAACGT GGAGGGCAGG 
ATAGAGCCAC CGCCTGGGAA GCACAACGAC ATTGACGTGT TCATGCCTAC CCTCCCAGTG 
CCCACTGTAG CCATGGAGGT GCGGCCATCA CCAAGCACCC CCCTGGAGGT CCCTCTCAAT 
GCCTCCAGCA CCAATGCCAC AGAGGATCAC CCAGAAACCA ATGCCGTAGA TGAACCCTAC 
AAAATCCATG GCCTGGAAGA TGAAGTCCAG CCACCCAACC TAATCCCTCG ACGACCGAGC 
CCCTATGAAA AGACCAGAAA CCAAAGAATC CAAGAGCTCA TTGATGAGAT GCGGAAGAAA 
GAGATGCTCG GAAAGTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expanding the clinical and mutational spectrum of the Ehlers-Danlos syndrome, dermatosparaxis type.
Genetics in medicine : official journal of the American College of Medical Genetics18(9)882-91(2016 Sep)
Van Damme T,Colige A,Syx D,Giunta C,Lindert U,Rohrbach M,Aryani O,Alanay Y,Simsek-Kiper P?,Kroes HY,Devriendt K,Thiry M,Symoens S,De Paepe A,Malfait F

Induction of human ADAMTS-2 gene expression by IL-1? is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells.
Gene573(2)321-7(2015 Dec)
Alper M,Aydemir AT,K??kar F

The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.
Matrix biology : journal of the International Society for Matrix Biology44-4646-53(2015 May-Jul)
Bekhouche M,Colige A

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ADAMTS2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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