MAPK8IP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAPK8IP1
Entrez Gene ID	9479
Full Name	mitogen-activated protein kinase 8 interacting protein 1
Synonyms	IB1,JIP-1,JIP1,PRKM8IP
General protein information	Preferred Names mitogen-activated protein kinase 8 interacting protein 1 Names C-Jun-amino-terminal kinase-interacting protein 1 IB-1 JNK MAP kinase scaffold protein 1 JNK-interacting protein 1 PRKM8 interacting protein islet-brain 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p11.2
Summary	This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq, May 2011].
Disorder MIM:	604641
Disorder Html:	{Diabetes mellitus, noninsulin-dependent}, 125853 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005456.3	NP_005447.1	C-Jun-amino-terminal kinase-interacting protein 1
XM_005253226.3	XP_005253283.1	C-Jun-amino-terminal kinase-interacting protein 1 isoform X1
NM_005456.4	NP_005447.1	C-Jun-amino-terminal kinase-interacting protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	MAPK8IP1	NP_005447.1
Canis lupus familiaris (dog)	MAPK8IP1	XP_005631786.1
Rattus norvegicus (Norway rat)	Mapk8ip1	NP_446229.1
Gallus gallus (chicken)	MAPK8IP1	XP_421126.4
	MAPK8IP1	XP_001113132.1
Danio rerio (zebrafish)	LOC100333948	XP_005172441.1
Bos taurus (cattle)	MAPK8IP1	NP_001095978.1
Pan troglodytes (chimpanzee)	MAPK8IP1	XP_001160866.1
Mus musculus (house mouse)	Mapk8ip1	NP_035292.2
Xenopus tropicalis (tropical clawed frog)	mapk8ip1	XP_002934139.2

Gene Ontology
Bibliography

Related articles in PubMed

A molecular dynamics study of the binary complexes of APP, JIP1, and the cargo binding domain of KLC.
Taylor CA, Miller BR 3rd, Shah SS, Parish CA
Proteins85(2)221-234(2017 Feb)

Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or A? production.
Vagnoni A, Glennon EB, Perkinton MS, Gray EH, Noble W, Miller CC
Human molecular genetics22(22)4646-52(2013 Nov)

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M, , Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr, , Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, H?hn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ, , Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD, , Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, P?rssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN
American journal of human genetics93(2)264-77(2013 Aug)

The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.
van den Berg MC, van Gogh IJ, Smits AM, van Triest M, Dansen TB, Visscher M, Polderman PE, Vliem MJ, Rehmann H, Burgering BM
The Journal of biological chemistry288(30)21729-41(2013 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

All binary complexes (KLC1:APP, KLC1:JIP1, and APP:JIP1) contain conformations with favorable binding free energies indicating that KLC1 and JIP1 may take part in APP transport in Alzheimer's disease patients.
Title: A molecular dynamics study of the binary complexes of APP, JIP1, and the cargo binding domain of KLC.

analysis of the role of JIP1 in APP transport; knockdown of JIP1 did not affect either amyloid precursor protein transport or amyloid-beta peptide production
Title: Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or A? production.

Data show that small GTPase RALA regulates formation of a JIP1 (C-Jun-amino-terminal-interacting protein 1) scaffold complex to propagate JNK signaling toward FOXO4 (forkhead box O transcription factor) in response to reactive oxygen species (ROS).
Title: The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.

In resected pancreatic cancer, carriers of a minor allele for rs3824872 (MAPK8IP1) were associated with a survival advantage compared with noncarriers with an additional 2-year survival if both minor alleles were present.
Title: Survival is associated with genetic variation in inflammatory pathway genes among patients with resected and unresected pancreatic cancer.

Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic beta cell death
Title: Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic ? cell death.

The following MAPK8IP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAPK8IP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18414	NM_005456.4 Latest version!	Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu45104	XM_005253226.3 Latest version!	Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu18414	NM_005456.3	Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAPK8IP1 ( NM_005456.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005447.1 Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), mRNA.

Price & Availability↑

CloneID	OHu18414
Clone ID Related Accession (Same CDS sequence)	NM_005456.3 , NM_005456.4
Accession Version	NM_005456.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	C-Jun-amino-terminal kinase-interacting protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC068470.1, AF074091.1 and AF007134.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_005456.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068470.1, AF074091.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000241014.6/ ENSP00000241014.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGAGC GAGAAAGCGG CGGCCTGGGA GGGGGGGCCG CGTCCCCGCC CGCCGCCTCC 
CCGTTCCTGG GGCTGCACAT CGCTTCGCCT CCCAATTTCA GGCTCACCCA TGACATCAGC 
CTGGAGGAGT TTGAGGATGA AGACCTCTCG GAGATCACTG ATGAGTGTGG CATCAGCTTA 
CAGTGCAAAG ACACCCTGTC CTTACGGCCC CCGCGCGCCG GGCTGCTCTC TGCGGGCGGC 
GGCGGCGCGG GGAGCCGGTT GCAGGCCGAG ATGCTGCAGA TGGACCTGAT CGACGCGACG 
GGGGACACTC CCGGGGCCGA GGACGACGAG GAGGACGACG ACGAGGAGCG CGCGGCCCGG 
CGGCCGGGAG CGGGGCCGCC CAAGGCCGAG TCCGGCCAGG AGCCGGCGTC CCGCGGCCAG 
GGCCAGAGCC AAGGCCAGAG CCAGGGCCCG GGCAGCGGGG ACACGTACCG GCCCAAGCGG 
CCCACCACGC TCAACCTCTT TCCGCAGGTG CCGCGGTCTC AGGACACACT GAATAATAAT 
TCTCTGGGCA AAAAGCACAG TTGGCAGGAT CGGGTGTCTC GATCATCCTC ACCCCTGAAG 
ACAGGGGAGC AGACACCACC GCATGAACAC ATCTGCCTGA GCGATGAGCT GCCCCCCCAG 
AGCGGCCCCG CCCCCACCAC AGATCGAGGC ACCTCCACCG ACAGCCCTTG CCGCCGCAGC 
ACAGCCACCC AGATGGCACC TCCGGGTGGT CCCCCTGCTG CCCCGCCTGG GGGTCGGGGC 
CACTCGCATC GAGACCGAAT CCACTACCAG GCCGATGTGC GACTAGAGGC CACTGAGGAG 
ATCTACCTGA CCCCAGTGCA GAGGCCCCCA GACGCTGCAG AGCCCACCTC CGCCTTCCTG 
CCGCCCACTG AGAGCCGGAT GTCAGTCAGC TCCGATCCAG ACCCTGCCGC CTACCCCTCC 
ACGGCAGGGC GGCCGCACCC CTCCATCAGT GAAGAGGAAG AGGGCTTCGA CTGCCTGTCG 
TCCCCAGAGC GGGCTGAGCC CCCAGGCGGA GGGTGGCGGG GGAGCCTGGG GGAGCCGCCG 
CCACCTCCAC GGGCCTCTCT GAGCTCGGAC ACCAGCGCCC TGTCCTATGA CTCTGTCAAG 
TACACGCTGG TGGTAGATGA GCATGCACAG CTGGAGCTGG TGAGCCTGCG GCCGTGCTTC 
GGAGACTACA GTGACGAGAG TGACTCTGCC ACCGTCTATG ACAACTGTGC CTCCGTCTCC 
TCGCCCTATG AGTCGGCCAT CGGAGAGGAA TATGAGGAGG CCCCGCGGCC CCAGCCCCCT 
GCCTGCCTCT CCGAGGACTC CACGCCTGAT GAACCCGACG TCCATTTCTC CAAGAAATTC 
CTGAACGTCT TCATGAGTGG CCGCTCCCGC TCCTCCAGTG CTGAGTCCTT CGGGCTGTTC 
TCCTGCATCA TCAACGGGGA GGAGCAGGAG CAGACCCACC GGGCCATATT CAGGTTTGTG 
CCTCGACACG AAGACGAACT TGAGCTGGAA GTGGATGACC CTCTGCTAGT GGAGCTCCAG 
GCTGAAGACT ACTGGTACGA GGCCTACAAC ATGCGCACTG GTGCCCGGGG TGTCTTTCCT 
GCCTATTACG CCATCGAGGT CACCAAGGAG CCCGAGCACA TGGCAGCCCT GGCCAAAAAC 
AGTGACTGGG TGGACCAGTT CCGGGTGAAG TTCCTGGGCT CAGTCCAGGT TCCCTATCAC 
AAGGGCAATG ACGTCCTCTG TGCTGCTATG CAAAAGATTG CCACCACCCG CCGGCTCACC 
GTGCACTTTA ACCCGCCCTC CAGCTGTGTC CTGGAGATCA GCGTGCGGGG TGTGAAGATA 
GGCGTCAAGG CCGATGACTC CCAGGAGGCC AAGGGGAATA AATGTAGCCA CTTTTTCCAG 
TTAAAAAACA TCTCTTTCTG CGGATATCAT CCAAAGAACA ACAAGTACTT TGGGTTCATC 
ACCAAGCACC CCGCCGACCA CCGGTTTGCC TGCCACGTCT TTGTGTCTGA AGACTCCACC 
AAAGCCCTGG CAGAGTCCGT GGGGAGAGCA TTCCAGCAGT TCTACAAGCA GTTTGTGGAG 
TACACCTGCC CCACAGAAGA TATCTACCTG GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005447.1
CDS	171..2306
Translation	MAERESGGLGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGGGGAGSRLQAEMLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQSGPAPTTDRGTSTDSPCRRSTATQMAPPGGPPAAPPGGRGHSHRDRIHYQADVRLEATEEIYLTPVQRPPDAAEPTSAFLPPTESRMSVSSDPDPAAYPSTAGRPHPSISEEEEGFDCLSSPERAEPPGGGWRGSLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASVSSPYESAIGEEYEEAPRPQPPACLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE

Target ORF information:

RefSeq Version	NM_005456.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005456.4

ORF Insert Sequence:

ATGGCGGAGC GAGAAAGCGG CGGCCTGGGA GGGGGGGCCG CGTCCCCGCC CGCCGCCTCC 
CCGTTCCTGG GGCTGCACAT CGCTTCGCCT CCCAATTTCA GGCTCACCCA TGACATCAGC 
CTGGAGGAGT TTGAGGATGA AGACCTCTCG GAGATCACTG ATGAGTGTGG CATCAGCTTA 
CAGTGCAAAG ACACCCTGTC CTTACGGCCC CCGCGCGCCG GGCTGCTCTC TGCGGGCGGC 
GGCGGCGCGG GGAGCCGGTT GCAGGCCGAG ATGCTGCAGA TGGACCTGAT CGACGCGACG 
GGGGACACTC CCGGGGCCGA GGACGACGAG GAGGACGACG ACGAGGAGCG CGCGGCCCGG 
CGGCCGGGAG CGGGGCCGCC CAAGGCCGAG TCCGGCCAGG AGCCGGCGTC CCGCGGCCAG 
GGCCAGAGCC AAGGCCAGAG CCAGGGCCCG GGCAGCGGGG ACACGTACCG GCCCAAGCGG 
CCCACCACGC TCAACCTCTT TCCGCAGGTG CCGCGGTCTC AGGACACACT GAATAATAAT 
TCTCTGGGCA AAAAGCACAG TTGGCAGGAT CGGGTGTCTC GATCATCCTC ACCCCTGAAG 
ACAGGGGAGC AGACACCACC GCATGAACAC ATCTGCCTGA GCGATGAGCT GCCCCCCCAG 
AGCGGCCCCG CCCCCACCAC AGATCGAGGC ACCTCCACCG ACAGCCCTTG CCGCCGCAGC 
ACAGCCACCC AGATGGCACC TCCGGGTGGT CCCCCTGCTG CCCCGCCTGG GGGTCGGGGC 
CACTCGCATC GAGACCGAAT CCACTACCAG GCCGATGTGC GACTAGAGGC CACTGAGGAG 
ATCTACCTGA CCCCAGTGCA GAGGCCCCCA GACGCTGCAG AGCCCACCTC CGCCTTCCTG 
CCGCCCACTG AGAGCCGGAT GTCAGTCAGC TCCGATCCAG ACCCTGCCGC CTACCCCTCC 
ACGGCAGGGC GGCCGCACCC CTCCATCAGT GAAGAGGAAG AGGGCTTCGA CTGCCTGTCG 
TCCCCAGAGC GGGCTGAGCC CCCAGGCGGA GGGTGGCGGG GGAGCCTGGG GGAGCCGCCG 
CCACCTCCAC GGGCCTCTCT GAGCTCGGAC ACCAGCGCCC TGTCCTATGA CTCTGTCAAG 
TACACGCTGG TGGTAGATGA GCATGCACAG CTGGAGCTGG TGAGCCTGCG GCCGTGCTTC 
GGAGACTACA GTGACGAGAG TGACTCTGCC ACCGTCTATG ACAACTGTGC CTCCGTCTCC 
TCGCCCTATG AGTCGGCCAT CGGAGAGGAA TATGAGGAGG CCCCGCGGCC CCAGCCCCCT 
GCCTGCCTCT CCGAGGACTC CACGCCTGAT GAACCCGACG TCCATTTCTC CAAGAAATTC 
CTGAACGTCT TCATGAGTGG CCGCTCCCGC TCCTCCAGTG CTGAGTCCTT CGGGCTGTTC 
TCCTGCATCA TCAACGGGGA GGAGCAGGAG CAGACCCACC GGGCCATATT CAGGTTTGTG 
CCTCGACACG AAGACGAACT TGAGCTGGAA GTGGATGACC CTCTGCTAGT GGAGCTCCAG 
GCTGAAGACT ACTGGTACGA GGCCTACAAC ATGCGCACTG GTGCCCGGGG TGTCTTTCCT 
GCCTATTACG CCATCGAGGT CACCAAGGAG CCCGAGCACA TGGCAGCCCT GGCCAAAAAC 
AGTGACTGGG TGGACCAGTT CCGGGTGAAG TTCCTGGGCT CAGTCCAGGT TCCCTATCAC 
AAGGGCAATG ACGTCCTCTG TGCTGCTATG CAAAAGATTG CCACCACCCG CCGGCTCACC 
GTGCACTTTA ACCCGCCCTC CAGCTGTGTC CTGGAGATCA GCGTGCGGGG TGTGAAGATA 
GGCGTCAAGG CCGATGACTC CCAGGAGGCC AAGGGGAATA AATGTAGCCA CTTTTTCCAG 
TTAAAAAACA TCTCTTTCTG CGGATATCAT CCAAAGAACA ACAAGTACTT TGGGTTCATC 
ACCAAGCACC CCGCCGACCA CCGGTTTGCC TGCCACGTCT TTGTGTCTGA AGACTCCACC 
AAAGCCCTGG CAGAGTCCGT GGGGAGAGCA TTCCAGCAGT TCTACAAGCA GTTTGTGGAG 
TACACCTGCC CCACAGAAGA TATCTACCTG GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPK8IP1 ( NM_005456.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005447.1 Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), mRNA.

Price & Availability↑

CloneID	OHu18414
Clone ID Related Accession (Same CDS sequence)	NM_005456.3 , NM_005456.4
Accession Version	NM_005456.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	C-Jun-amino-terminal kinase-interacting protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB473314.1, BC068470.1, AF074091.1 and AF007134.1. This sequence is a reference standard in the RefSeqGene project. On May 14, 2011 this sequence version replaced NM_005456.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068470.1, AF074091.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGC GAGAAAGCGG CGGCCTGGGA GGGGGGGCCG CGTCCCCGCC CGCCGCCTCC 
CCGTTCCTGG GGCTGCACAT CGCTTCGCCT CCCAATTTCA GGCTCACCCA TGACATCAGC 
CTGGAGGAGT TTGAGGATGA AGACCTCTCG GAGATCACTG ATGAGTGTGG CATCAGCTTA 
CAGTGCAAAG ACACCCTGTC CTTACGGCCC CCGCGCGCCG GGCTGCTCTC TGCGGGCGGC 
GGCGGCGCGG GGAGCCGGTT GCAGGCCGAG ATGCTGCAGA TGGACCTGAT CGACGCGACG 
GGGGACACTC CCGGGGCCGA GGACGACGAG GAGGACGACG ACGAGGAGCG CGCGGCCCGG 
CGGCCGGGAG CGGGGCCGCC CAAGGCCGAG TCCGGCCAGG AGCCGGCGTC CCGCGGCCAG 
GGCCAGAGCC AAGGCCAGAG CCAGGGCCCG GGCAGCGGGG ACACGTACCG GCCCAAGCGG 
CCCACCACGC TCAACCTCTT TCCGCAGGTG CCGCGGTCTC AGGACACACT GAATAATAAT 
TCTCTGGGCA AAAAGCACAG TTGGCAGGAT CGGGTGTCTC GATCATCCTC ACCCCTGAAG 
ACAGGGGAGC AGACACCACC GCATGAACAC ATCTGCCTGA GCGATGAGCT GCCCCCCCAG 
AGCGGCCCCG CCCCCACCAC AGATCGAGGC ACCTCCACCG ACAGCCCTTG CCGCCGCAGC 
ACAGCCACCC AGATGGCACC TCCGGGTGGT CCCCCTGCTG CCCCGCCTGG GGGTCGGGGC 
CACTCGCATC GAGACCGAAT CCACTACCAG GCCGATGTGC GACTAGAGGC CACTGAGGAG 
ATCTACCTGA CCCCAGTGCA GAGGCCCCCA GACGCTGCAG AGCCCACCTC CGCCTTCCTG 
CCGCCCACTG AGAGCCGGAT GTCAGTCAGC TCCGATCCAG ACCCTGCCGC CTACCCCTCC 
ACGGCAGGGC GGCCGCACCC CTCCATCAGT GAAGAGGAAG AGGGCTTCGA CTGCCTGTCG 
TCCCCAGAGC GGGCTGAGCC CCCAGGCGGA GGGTGGCGGG GGAGCCTGGG GGAGCCGCCG 
CCACCTCCAC GGGCCTCTCT GAGCTCGGAC ACCAGCGCCC TGTCCTATGA CTCTGTCAAG 
TACACGCTGG TGGTAGATGA GCATGCACAG CTGGAGCTGG TGAGCCTGCG GCCGTGCTTC 
GGAGACTACA GTGACGAGAG TGACTCTGCC ACCGTCTATG ACAACTGTGC CTCCGTCTCC 
TCGCCCTATG AGTCGGCCAT CGGAGAGGAA TATGAGGAGG CCCCGCGGCC CCAGCCCCCT 
GCCTGCCTCT CCGAGGACTC CACGCCTGAT GAACCCGACG TCCATTTCTC CAAGAAATTC 
CTGAACGTCT TCATGAGTGG CCGCTCCCGC TCCTCCAGTG CTGAGTCCTT CGGGCTGTTC 
TCCTGCATCA TCAACGGGGA GGAGCAGGAG CAGACCCACC GGGCCATATT CAGGTTTGTG 
CCTCGACACG AAGACGAACT TGAGCTGGAA GTGGATGACC CTCTGCTAGT GGAGCTCCAG 
GCTGAAGACT ACTGGTACGA GGCCTACAAC ATGCGCACTG GTGCCCGGGG TGTCTTTCCT 
GCCTATTACG CCATCGAGGT CACCAAGGAG CCCGAGCACA TGGCAGCCCT GGCCAAAAAC 
AGTGACTGGG TGGACCAGTT CCGGGTGAAG TTCCTGGGCT CAGTCCAGGT TCCCTATCAC 
AAGGGCAATG ACGTCCTCTG TGCTGCTATG CAAAAGATTG CCACCACCCG CCGGCTCACC 
GTGCACTTTA ACCCGCCCTC CAGCTGTGTC CTGGAGATCA GCGTGCGGGG TGTGAAGATA 
GGCGTCAAGG CCGATGACTC CCAGGAGGCC AAGGGGAATA AATGTAGCCA CTTTTTCCAG 
TTAAAAAACA TCTCTTTCTG CGGATATCAT CCAAAGAACA ACAAGTACTT TGGGTTCATC 
ACCAAGCACC CCGCCGACCA CCGGTTTGCC TGCCACGTCT TTGTGTCTGA AGACTCCACC 
AAAGCCCTGG CAGAGTCCGT GGGGAGAGCA TTCCAGCAGT TCTACAAGCA GTTTGTGGAG 
TACACCTGCC CCACAGAAGA TATCTACCTG GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005447.1
CDS	326..2461
Translation	MAERESGGLGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGGGGAGSRLQAEMLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQSGPAPTTDRGTSTDSPCRRSTATQMAPPGGPPAAPPGGRGHSHRDRIHYQADVRLEATEEIYLTPVQRPPDAAEPTSAFLPPTESRMSVSSDPDPAAYPSTAGRPHPSISEEEEGFDCLSSPERAEPPGGGWRGSLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASVSSPYESAIGEEYEEAPRPQPPACLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE

Target ORF information:

RefSeq Version	NM_005456.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005456.3

ORF Insert Sequence:

ATGGCGGAGC GAGAAAGCGG CGGCCTGGGA GGGGGGGCCG CGTCCCCGCC CGCCGCCTCC 
CCGTTCCTGG GGCTGCACAT CGCTTCGCCT CCCAATTTCA GGCTCACCCA TGACATCAGC 
CTGGAGGAGT TTGAGGATGA AGACCTCTCG GAGATCACTG ATGAGTGTGG CATCAGCTTA 
CAGTGCAAAG ACACCCTGTC CTTACGGCCC CCGCGCGCCG GGCTGCTCTC TGCGGGCGGC 
GGCGGCGCGG GGAGCCGGTT GCAGGCCGAG ATGCTGCAGA TGGACCTGAT CGACGCGACG 
GGGGACACTC CCGGGGCCGA GGACGACGAG GAGGACGACG ACGAGGAGCG CGCGGCCCGG 
CGGCCGGGAG CGGGGCCGCC CAAGGCCGAG TCCGGCCAGG AGCCGGCGTC CCGCGGCCAG 
GGCCAGAGCC AAGGCCAGAG CCAGGGCCCG GGCAGCGGGG ACACGTACCG GCCCAAGCGG 
CCCACCACGC TCAACCTCTT TCCGCAGGTG CCGCGGTCTC AGGACACACT GAATAATAAT 
TCTCTGGGCA AAAAGCACAG TTGGCAGGAT CGGGTGTCTC GATCATCCTC ACCCCTGAAG 
ACAGGGGAGC AGACACCACC GCATGAACAC ATCTGCCTGA GCGATGAGCT GCCCCCCCAG 
AGCGGCCCCG CCCCCACCAC AGATCGAGGC ACCTCCACCG ACAGCCCTTG CCGCCGCAGC 
ACAGCCACCC AGATGGCACC TCCGGGTGGT CCCCCTGCTG CCCCGCCTGG GGGTCGGGGC 
CACTCGCATC GAGACCGAAT CCACTACCAG GCCGATGTGC GACTAGAGGC CACTGAGGAG 
ATCTACCTGA CCCCAGTGCA GAGGCCCCCA GACGCTGCAG AGCCCACCTC CGCCTTCCTG 
CCGCCCACTG AGAGCCGGAT GTCAGTCAGC TCCGATCCAG ACCCTGCCGC CTACCCCTCC 
ACGGCAGGGC GGCCGCACCC CTCCATCAGT GAAGAGGAAG AGGGCTTCGA CTGCCTGTCG 
TCCCCAGAGC GGGCTGAGCC CCCAGGCGGA GGGTGGCGGG GGAGCCTGGG GGAGCCGCCG 
CCACCTCCAC GGGCCTCTCT GAGCTCGGAC ACCAGCGCCC TGTCCTATGA CTCTGTCAAG 
TACACGCTGG TGGTAGATGA GCATGCACAG CTGGAGCTGG TGAGCCTGCG GCCGTGCTTC 
GGAGACTACA GTGACGAGAG TGACTCTGCC ACCGTCTATG ACAACTGTGC CTCCGTCTCC 
TCGCCCTATG AGTCGGCCAT CGGAGAGGAA TATGAGGAGG CCCCGCGGCC CCAGCCCCCT 
GCCTGCCTCT CCGAGGACTC CACGCCTGAT GAACCCGACG TCCATTTCTC CAAGAAATTC 
CTGAACGTCT TCATGAGTGG CCGCTCCCGC TCCTCCAGTG CTGAGTCCTT CGGGCTGTTC 
TCCTGCATCA TCAACGGGGA GGAGCAGGAG CAGACCCACC GGGCCATATT CAGGTTTGTG 
CCTCGACACG AAGACGAACT TGAGCTGGAA GTGGATGACC CTCTGCTAGT GGAGCTCCAG 
GCTGAAGACT ACTGGTACGA GGCCTACAAC ATGCGCACTG GTGCCCGGGG TGTCTTTCCT 
GCCTATTACG CCATCGAGGT CACCAAGGAG CCCGAGCACA TGGCAGCCCT GGCCAAAAAC 
AGTGACTGGG TGGACCAGTT CCGGGTGAAG TTCCTGGGCT CAGTCCAGGT TCCCTATCAC 
AAGGGCAATG ACGTCCTCTG TGCTGCTATG CAAAAGATTG CCACCACCCG CCGGCTCACC 
GTGCACTTTA ACCCGCCCTC CAGCTGTGTC CTGGAGATCA GCGTGCGGGG TGTGAAGATA 
GGCGTCAAGG CCGATGACTC CCAGGAGGCC AAGGGGAATA AATGTAGCCA CTTTTTCCAG 
TTAAAAAACA TCTCTTTCTG CGGATATCAT CCAAAGAACA ACAAGTACTT TGGGTTCATC 
ACCAAGCACC CCGCCGACCA CCGGTTTGCC TGCCACGTCT TTGTGTCTGA AGACTCCACC 
AAAGCCCTGG CAGAGTCCGT GGGGAGAGCA TTCCAGCAGT TCTACAAGCA GTTTGTGGAG 
TACACCTGCC CCACAGAAGA TATCTACCTG GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAPK8IP1 ( XM_005253226.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005253283.1 Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), transcript variant X1, mRNA.

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CloneID	OHu45104
Clone ID Related Accession (Same CDS sequence)	XM_005253226.3
Accession Version	XM_005253226.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2106bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	C-Jun-amino-terminal kinase-interacting protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005253226.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCTGG TGCTGAAGAT GGATTCGAGC CCAGACAATG ACAGCTGGTT GGAGGATCAA 
TGGGAGCGCT GGCTCACCCA TGACATCAGC CTGGAGGAGT TTGAGGATGA AGACCTCTCG 
GAGATCACTG ATGAGTGTGG CATCAGCTTA CAGTGCAAAG ACACCCTGTC CTTACGGCCC 
CCGCGCGCCG GGCTGCTCTC TGCGGGCGGC GGCGGCGCGG GGAGCCGGTT GCAGGCCGAG 
ATGCTGCAGA TGGACCTGAT CGACGCGACG GGGGACACTC CCGGGGCCGA GGACGACGAG 
GAGGACGACG ACGAGGAGCG CGCGGCCCGG CGGCCGGGAG CGGGGCCGCC CAAGGCCGAG 
TCCGGCCAGG AGCCGGCGTC CCGCGGCCAG GGCCAGAGCC AAGGCCAGAG CCAGGGCCCG 
GGCAGCGGGG ACACGTACCG GCCCAAGCGG CCCACCACGC TCAACCTCTT TCCGCAGGTG 
CCGCGGTCTC AGGACACACT GAATAATAAT TCTCTGGGCA AAAAGCACAG TTGGCAGGAT 
CGGGTGTCTC GATCATCCTC ACCCCTGAAG ACAGGGGAGC AGACACCACC GCATGAACAC 
ATCTGCCTGA GCGATGAGCT GCCCCCCCAG AGCGGCCCCG CCCCCACCAC AGATCGAGGC 
ACCTCCACCG ACAGCCCTTG CCGCCGCAGC ACAGCCACCC AGATGGCACC TCCGGGTGGT 
CCCCCTGCTG CCCCGCCTGG GGGTCGGGGC CACTCGCATC GAGACCGAAT CCACTACCAG 
GCCGATGTGC GACTAGAGGC CACTGAGGAG ATCTACCTGA CCCCAGTGCA GAGGCCCCCA 
GACGCTGCAG AGCCCACCTC CGCCTTCCTG CCGCCCACTG AGAGCCGGAT GTCAGTCAGC 
TCCGATCCAG ACCCTGCCGC CTACCCCTCC ACGGCAGGGC GGCCGCACCC CTCCATCAGT 
GAAGAGGAAG AGGGCTTCGA CTGCCTGTCG TCCCCAGAGC GGGCTGAGCC CCCAGGCGGA 
GGGTGGCGGG GGAGCCTGGG GGAGCCGCCG CCACCTCCAC GGGCCTCTCT GAGCTCGGAC 
ACCAGCGCCC TGTCCTATGA CTCTGTCAAG TACACGCTGG TGGTAGATGA GCATGCACAG 
CTGGAGCTGG TGAGCCTGCG GCCGTGCTTC GGAGACTACA GTGACGAGAG TGACTCTGCC 
ACCGTCTATG ACAACTGTGC CTCCGTCTCC TCGCCCTATG AGTCGGCCAT CGGAGAGGAA 
TATGAGGAGG CCCCGCGGCC CCAGCCCCCT GCCTGCCTCT CCGAGGACTC CACGCCTGAT 
GAACCCGACG TCCATTTCTC CAAGAAATTC CTGAACGTCT TCATGAGTGG CCGCTCCCGC 
TCCTCCAGTG CTGAGTCCTT CGGGCTGTTC TCCTGCATCA TCAACGGGGA GGAGCAGGAG 
CAGACCCACC GGGCCATATT CAGGTTTGTG CCTCGACACG AAGACGAACT TGAGCTGGAA 
GTGGATGACC CTCTGCTAGT GGAGCTCCAG GCTGAAGACT ACTGGTACGA GGCCTACAAC 
ATGCGCACTG GTGCCCGGGG TGTCTTTCCT GCCTATTACG CCATCGAGGT CACCAAGGAG 
CCCGAGCACA TGGCAGCCCT GGCCAAAAAC AGTGACTGGG TGGACCAGTT CCGGGTGAAG 
TTCCTGGGCT CAGTCCAGGT TCCCTATCAC AAGGGCAATG ACGTCCTCTG TGCTGCTATG 
CAAAAGATTG CCACCACCCG CCGGCTCACC GTGCACTTTA ACCCGCCCTC CAGCTGTGTC 
CTGGAGATCA GCGTGCGGGG TGTGAAGATA GGCGTCAAGG CCGATGACTC CCAGGAGGCC 
AAGGGGAATA AATGTAGCCA CTTTTTCCAG TTAAAAAACA TCTCTTTCTG CGGATATCAT 
CCAAAGAACA ACAAGTACTT TGGGTTCATC ACCAAGCACC CCGCCGACCA CCGGTTTGCC 
TGCCACGTCT TTGTGTCTGA AGACTCCACC AAAGCCCTGG CAGAGTCCGT GGGGAGAGCA 
TTCCAGCAGT TCTACAAGCA GTTTGTGGAG TACACCTGCC CCACAGAAGA TATCTACCTG 
GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005253283.1
CDS	401..2506
Translation	MQLVLKMDSSPDNDSWLEDQWERWLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGGGGAGSRLQAEMLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQSGPAPTTDRGTSTDSPCRRSTATQMAPPGGPPAAPPGGRGHSHRDRIHYQADVRLEATEEIYLTPVQRPPDAAEPTSAFLPPTESRMSVSSDPDPAAYPSTAGRPHPSISEEEEGFDCLSSPERAEPPGGGWRGSLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASVSSPYESAIGEEYEEAPRPQPPACLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE

Target ORF information:

RefSeq Version	XM_005253226.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005253226.3

ORF Insert Sequence:

ATGCAGCTGG TGCTGAAGAT GGATTCGAGC CCAGACAATG ACAGCTGGTT GGAGGATCAA 
TGGGAGCGCT GGCTCACCCA TGACATCAGC CTGGAGGAGT TTGAGGATGA AGACCTCTCG 
GAGATCACTG ATGAGTGTGG CATCAGCTTA CAGTGCAAAG ACACCCTGTC CTTACGGCCC 
CCGCGCGCCG GGCTGCTCTC TGCGGGCGGC GGCGGCGCGG GGAGCCGGTT GCAGGCCGAG 
ATGCTGCAGA TGGACCTGAT CGACGCGACG GGGGACACTC CCGGGGCCGA GGACGACGAG 
GAGGACGACG ACGAGGAGCG CGCGGCCCGG CGGCCGGGAG CGGGGCCGCC CAAGGCCGAG 
TCCGGCCAGG AGCCGGCGTC CCGCGGCCAG GGCCAGAGCC AAGGCCAGAG CCAGGGCCCG 
GGCAGCGGGG ACACGTACCG GCCCAAGCGG CCCACCACGC TCAACCTCTT TCCGCAGGTG 
CCGCGGTCTC AGGACACACT GAATAATAAT TCTCTGGGCA AAAAGCACAG TTGGCAGGAT 
CGGGTGTCTC GATCATCCTC ACCCCTGAAG ACAGGGGAGC AGACACCACC GCATGAACAC 
ATCTGCCTGA GCGATGAGCT GCCCCCCCAG AGCGGCCCCG CCCCCACCAC AGATCGAGGC 
ACCTCCACCG ACAGCCCTTG CCGCCGCAGC ACAGCCACCC AGATGGCACC TCCGGGTGGT 
CCCCCTGCTG CCCCGCCTGG GGGTCGGGGC CACTCGCATC GAGACCGAAT CCACTACCAG 
GCCGATGTGC GACTAGAGGC CACTGAGGAG ATCTACCTGA CCCCAGTGCA GAGGCCCCCA 
GACGCTGCAG AGCCCACCTC CGCCTTCCTG CCGCCCACTG AGAGCCGGAT GTCAGTCAGC 
TCCGATCCAG ACCCTGCCGC CTACCCCTCC ACGGCAGGGC GGCCGCACCC CTCCATCAGT 
GAAGAGGAAG AGGGCTTCGA CTGCCTGTCG TCCCCAGAGC GGGCTGAGCC CCCAGGCGGA 
GGGTGGCGGG GGAGCCTGGG GGAGCCGCCG CCACCTCCAC GGGCCTCTCT GAGCTCGGAC 
ACCAGCGCCC TGTCCTATGA CTCTGTCAAG TACACGCTGG TGGTAGATGA GCATGCACAG 
CTGGAGCTGG TGAGCCTGCG GCCGTGCTTC GGAGACTACA GTGACGAGAG TGACTCTGCC 
ACCGTCTATG ACAACTGTGC CTCCGTCTCC TCGCCCTATG AGTCGGCCAT CGGAGAGGAA 
TATGAGGAGG CCCCGCGGCC CCAGCCCCCT GCCTGCCTCT CCGAGGACTC CACGCCTGAT 
GAACCCGACG TCCATTTCTC CAAGAAATTC CTGAACGTCT TCATGAGTGG CCGCTCCCGC 
TCCTCCAGTG CTGAGTCCTT CGGGCTGTTC TCCTGCATCA TCAACGGGGA GGAGCAGGAG 
CAGACCCACC GGGCCATATT CAGGTTTGTG CCTCGACACG AAGACGAACT TGAGCTGGAA 
GTGGATGACC CTCTGCTAGT GGAGCTCCAG GCTGAAGACT ACTGGTACGA GGCCTACAAC 
ATGCGCACTG GTGCCCGGGG TGTCTTTCCT GCCTATTACG CCATCGAGGT CACCAAGGAG 
CCCGAGCACA TGGCAGCCCT GGCCAAAAAC AGTGACTGGG TGGACCAGTT CCGGGTGAAG 
TTCCTGGGCT CAGTCCAGGT TCCCTATCAC AAGGGCAATG ACGTCCTCTG TGCTGCTATG 
CAAAAGATTG CCACCACCCG CCGGCTCACC GTGCACTTTA ACCCGCCCTC CAGCTGTGTC 
CTGGAGATCA GCGTGCGGGG TGTGAAGATA GGCGTCAAGG CCGATGACTC CCAGGAGGCC 
AAGGGGAATA AATGTAGCCA CTTTTTCCAG TTAAAAAACA TCTCTTTCTG CGGATATCAT 
CCAAAGAACA ACAAGTACTT TGGGTTCATC ACCAAGCACC CCGCCGACCA CCGGTTTGCC 
TGCCACGTCT TTGTGTCTGA AGACTCCACC AAAGCCCTGG CAGAGTCCGT GGGGAGAGCA 
TTCCAGCAGT TCTACAAGCA GTTTGTGGAG TACACCTGCC CCACAGAAGA TATCTACCTG 
GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A molecular dynamics study of the binary complexes of APP, JIP1, and the cargo binding domain of KLC.
Proteins85(2)221-234(2017 Feb)
Taylor CA,Miller BR 3rd,Shah SS,Parish CA

Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or A? production.
Human molecular genetics22(22)4646-52(2013 Nov)
Vagnoni A,Glennon EB,Perkinton MS,Gray EH,Noble W,Miller CC

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
American journal of human genetics93(2)264-77(2013 Aug)
Cheng CY,Schache M,Ikram MK,Young TL,Guggenheim JA,Vitart V,MacGregor S,Verhoeven VJ,Barathi VA,Liao J,Hysi PG,Bailey-Wilson JE,St Pourcain B,Kemp JP,McMahon G,Timpson NJ,Evans DM,Montgomery GW,Mishra A,Wang YX,Wang JJ,Rochtchina E,Polasek O,Wright AF,Amin N,van Leeuwen EM,Wilson JF,Pennell CE,van Duijn CM,de Jong PT,Vingerling JR,Zhou X,Chen P,Li R,Tay WT,Zheng Y,Chew M,,Burdon KP,Craig JE,Iyengar SK,Igo RP Jr,Lass JH Jr,,Chew EY,Haller T,Mihailov E,Metspalu A,Wedenoja J,Simpson CL,Wojciechowski R,H?hn R,Mirshahi A,Zeller T,Pfeiffer N,Lackner KJ,,Bettecken T,Meitinger T,Oexle K,Pirastu M,Portas L,Nag A,Williams KM,Yonova-Doing E,Klein R,Klein BE,Hosseini SM,Paterson AD,,Makela KM,Lehtimaki T,Kahonen M,Raitakari O,Yoshimura N,Matsuda F,Chen LJ,Pang CP,Yip SP,Yap MK,Meguro A,Mizuki N,Inoko H,Foster PJ,Zhao JH,Vithana E,Tai ES,Fan Q,Xu L,Campbell H,Fleck B,Rudan I,Aung T,Hofman A,Uitterlinden AG,Bencic G,Khor CC,Forward H,P?rssinen O,Mitchell P,Rivadeneira F,Hewitt AW,Williams C,Oostra BA,Teo YY,Hammond CJ,Stambolian D,Mackey DA,Klaver CC,Wong TY,Saw SM,Baird PN

The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.
The Journal of biological chemistry288(30)21729-41(2013 Jul)
van den Berg MC,van Gogh IJ,Smits AM,van Triest M,Dansen TB,Visscher M,Polderman PE,Vliem MJ,Rehmann H,Burgering BM

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MAPK8IP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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