SELENOF cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SELENOF
Entrez Gene ID	9403
Full Name	selenoprotein F
Synonyms	SEP15
General protein information	Preferred Names selenoprotein F Names selenoprotein F 15 kDa selenoprotein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p22.3
Summary	The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2016].
Disorder MIM:	606254

mRNA and Protein(s)

mRNA	Protein	Name
NM_004261.3	NP_004252.2	15 kDa selenoprotein isoform 1 precursor
NM_004261.4	NP_004252.2	selenoprotein F isoform 1 precursor
NM_203341.1	NP_976086.1	15 kDa selenoprotein isoform 2 precursor
NM_203341.2	NP_976086.1	selenoprotein F isoform 2 precursor
NM_004261.5	NP_004252.2	selenoprotein F isoform 1 precursor

Pathways from BioSystems

Homologies

	SEP15	NP_001152888.1
Bos taurus (cattle)	SEP15	NP_001029931.2
Gallus gallus (chicken)	SEP15	NP_001012944.2
Arabidopsis thaliana (thale cress)	AT1G05720	NP_563747.1
Xenopus tropicalis (tropical clawed frog)	sep15	NP_001165182.1
Homo sapiens (human)	SEP15	NP_004252.2
Pan troglodytes (chimpanzee)	SEP15	NP_001139315.1
Rattus norvegicus (Norway rat)	Sep15	NP_579831.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004986	XP_315090.2
Oryza sativa (rice)	Os01g0894500	NP_001045069.1
Canis lupus familiaris (dog)	SEP15	NP_001108232.1
Mus musculus (house mouse)	Sep15	NP_444332.1
Danio rerio (zebrafish)	sep15	NP_840079.1
Drosophila melanogaster (fruit fly)	CG7484	NP_649000.1
Caenorhabditis elegans (roundworm)	Y76B12C.3	NP_500152.1

Gene Ontology
Bibliography

Related articles in PubMed

Correlations of SELENOF and SELENOP genotypes with serum selenium levels and prostate cancer.
Ekoue DN, Ansong E, Liu L, Macias V, Deaton R, Lacher C, Picklo M, Nonn L, Gann PH, Kajdacsy-Balla A, Prins GS, Freeman VL, Diamond AM
The Prostate78(4)279-288(2018 Mar)

SEPP1 and SEP15 gene polymorphisms and susceptibility to breast cancer.
Mohammaddoust S, Salehi Z, Saeidi Saedi H
British journal of biomedical science75(1)36-39(2018 Jan)

Role of SEP15 Gene Polymorphisms in the Time of Progression to AIDS.
Benelli JL, de Medeiros RM, Matte MC, de Melo MG, de Matos Almeida SE, Fiegenbaum M
Genetic testing and molecular biomarkers20(7)383-7(2016 Jul)

The 811 C/T polymorphism in the 3' untranslated region of the selenoprotein 15-kDa (Sep15) gene and breast cancer in Caucasian women.
Watrowski R, Castillo-Tong DC, Fabjani G, Schuster E, Fischer M, Zeillinger R
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(1)1009-15(2016 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The allelic and genotypic frequencies did not differ between rapid and nonrapid progressors; however, the presence of the AA genotype of the rs5859 polymorphism was associated with a shorter time of progression to AIDS compared with GG homozygotes (hazard ratio = 3.62, 95% CI = 1.55-8.43, p = 0.003).
Title: Role of SEP15 Gene Polymorphisms in the Time of Progression to AIDS.

Genotype variation within the 3'-UTR of the SEP 15 gene showed no association with breast cancer risk or clinico-pathological parameters in Caucasian women.
Title: The 811 C/T polymorphism in the 3' untranslated region of the selenoprotein 15-kDa (Sep15) gene and breast cancer in Caucasian women.

Results suggest that SEP15 plays important roles in the regulation of the G1 phase during the cell cycle as well as in cell motility of Chang liver cells offering a novel functional link between the cell cycle and cell motility.
Title: Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells.

Sep15 in Chang liver cells regulates the pathway that antagonizes RhoA/ROCK/MLC-dependent non-apoptotic bleb formation.
Title: Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway.

Concerning rs561104, the serum selenium concentration was higher in CC homozygotes (5.65 +/- 1.11 mug/dL) compared with T carriers (4.88 +/- 1.25 mug/dL, P = .044).
Title: SLC30A3 and SEP15 gene polymorphisms influence the serum concentrations of zinc and selenium in mature adults.

The following SELENOF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SELENOF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13070	NM_004261.5 Latest version!	Homo sapiens selenoprotein F (SELENOF), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13161	NM_203341.2 Latest version!	Homo sapiens selenoprotein F (SELENOF), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu13070	NM_004261.3	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu13161	NM_203341.1	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu13070	NM_004261.4	Homo sapiens selenoprotein F (SELENOF), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SELENOF ( NM_004261.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_004252.2 Homo sapiens selenoprotein F (SELENOF), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13070
Clone ID Related Accession (Same CDS sequence)	NM_004261.3 , NM_004261.4 , NM_004261.5
Accession Version	NM_004261.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-12
Organism	Homo sapiens(human)
Product	selenoprotein F isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU941543.1, BC016359.1 and AK225640.1. On Nov 22, 2018 this sequence version replaced NM_004261.4. Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.84236.1, SRR3476690.1166565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000331835.10/ ENSP00000328729.6 protein contains selenocysteine :: PMID: 9535873, 10945981 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGCTTT TGTTAGGAGT GATAAACCCA AACTGTTCAG AGGACTGCAA 
ATCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA TGGGAACATT 
GCTGAAGAAC TGAGCATTCT CAAATGGAAC ACAGACAGTG TAGAAGAATT CCTGAGTGAA 
AAGTTGGAAC GCATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004252.2
CDS	16..513
Translation	MVAMAAGPSGCLVPAFGLRLLLATVLQAVSAFGAEFSSEACRELGFSSNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCG*KLGRFPQVQAFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLERI

Target ORF information:

RefSeq Version	NM_004261.5
Organism	Homo sapiens(human)
Definition	Homo sapiens selenoprotein F (SELENOF), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004261.5

ORF Insert Sequence:

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGCTTT TGTTAGGAGT GATAAACCCA AACTGTTCAG AGGACTGCAA 
ATCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA TGGGAACATT 
GCTGAAGAAC TGAGCATTCT CAAATGGAAC ACAGACAGTG TAGAAGAATT CCTGAGTGAA 
AAGTTGGAAC GCATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SELENOF ( NM_203341.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_976086.1 Homo sapiens selenoprotein F (SELENOF), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13161
Clone ID Related Accession (Same CDS sequence)	NM_203341.1 , NM_203341.2
Accession Version	NM_203341.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 375bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-12
Organism	Homo sapiens(human)
Product	selenoprotein F isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU941543.1, BC021697.1, BC016359.1 and AK225640.1. On Nov 4, 2016 this sequence version replaced NM_203341.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.105004.1, SRR1803617.76087.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 9535873, 10945981 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA 
TGGGAACATT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_976086.1
CDS	255..629
Translation	MVAMAAGPSGCLVPAFGLRLLLATVLQAVSAFGAEFSSEACRELGFSSNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCG*KLGRFPQVQVCPWFRPCIKAFGRQWEHC

Target ORF information:

RefSeq Version	NM_203341.2
Organism	Homo sapiens(human)
Definition	Homo sapiens selenoprotein F (SELENOF), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_203341.2

ORF Insert Sequence:

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA 
TGGGAACATT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SELENOF ( NM_004261.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004252.2 Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13070
Clone ID Related Accession (Same CDS sequence)	NM_004261.3 , NM_004261.4 , NM_004261.5
Accession Version	NM_004261.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-07-09
Organism	Homo sapiens(Human)
Product	15 kDa selenoprotein isoform 1 precursor
Comment

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGCTTT TGTTAGGAGT GATAAACCCA AACTGTTCAG AGGACTGCAA 
ATCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA TGGGAACATT 
GCTGAAGAAC TGAGCATTCT CAAATGGAAC ACAGACAGTG TAGAAGAATT CCTGAGTGAA 
AAGTTGGAAC GCATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004252.2
Translation	MVAMAAGPSGCLVPAFGLRLLLATVLQAVSAFGAEFSSEACRELGFSSNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCG*KLGRFPQVQAFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLERI

Target ORF information:

RefSeq Version	NM_004261.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004261.3

ORF Insert Sequence:

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGCTTT TGTTAGGAGT GATAAACCCA AACTGTTCAG AGGACTGCAA 
ATCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA TGGGAACATT 
GCTGAAGAAC TGAGCATTCT CAAATGGAAC ACAGACAGTG TAGAAGAATT CCTGAGTGAA 
AAGTTGGAAC GCATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SELENOF ( NM_004261.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004252.2 Homo sapiens selenoprotein F (SELENOF), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13070
Clone ID Related Accession (Same CDS sequence)	NM_004261.3 , NM_004261.4 , NM_004261.5
Accession Version	NM_004261.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-09
Organism	Homo sapiens(human)
Product	selenoprotein F isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU941543.1, BC016359.1 and AK225640.1. On Nov 4, 2016 this sequence version replaced NM_004261.3. Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.84236.1, SRR1163657.377113.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 9535873, 10945981 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGCTTT TGTTAGGAGT GATAAACCCA AACTGTTCAG AGGACTGCAA 
ATCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA TGGGAACATT 
GCTGAAGAAC TGAGCATTCT CAAATGGAAC ACAGACAGTG TAGAAGAATT CCTGAGTGAA 
AAGTTGGAAC GCATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004252.2
CDS	255..752
Translation	MVAMAAGPSGCLVPAFGLRLLLATVLQAVSAFGAEFSSEACRELGFSSNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCG*KLGRFPQVQAFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLERI

Target ORF information:

RefSeq Version	NM_004261.4
Organism	Homo sapiens(human)
Definition	Homo sapiens selenoprotein F (SELENOF), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004261.4

ORF Insert Sequence:

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGCTTT TGTTAGGAGT GATAAACCCA AACTGTTCAG AGGACTGCAA 
ATCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA TGGGAACATT 
GCTGAAGAAC TGAGCATTCT CAAATGGAAC ACAGACAGTG TAGAAGAATT CCTGAGTGAA 
AAGTTGGAAC GCATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SELENOF ( NM_203341.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_976086.1 Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13161
Clone ID Related Accession (Same CDS sequence)	NM_203341.1 , NM_203341.2
Accession Version	NM_203341.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 375bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-07-09
Organism	Homo sapiens(Human)
Product	15 kDa selenoprotein isoform 2 precursor
Comment

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA 
TGGGAACATT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_976086.1
Translation	MVAMAAGPSGCLVPAFGLRLLLATVLQAVSAFGAEFSSEACRELGFSSNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCG*KLGRFPQVQVCPWFRPCIKAFGRQWEHC

Target ORF information:

RefSeq Version	NM_203341.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_203341.1

ORF Insert Sequence:

ATGGTAGCGA TGGCGGCTGG GCCGAGTGGG TGTCTGGTGC CGGCGTTTGG GCTACGGTTG 
TTGTTGGCGA CTGTGCTTCA AGCGGTGTCT GCTTTTGGGG CAGAGTTTTC ATCGGAGGCA 
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTTTGCAGCT CTTGTGATCT TCTCGGACAG 
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT 
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG 
TTCCCTCAAG TCCAAGTATG TCCGTGGTTC AGACCCTGTA TTAAAGCTTT TGGACGACAA 
TGGGAACATT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Correlations of SELENOF and SELENOP genotypes with serum selenium levels and prostate cancer.
The Prostate78(4)279-288(2018 Mar)
Ekoue DN,Ansong E,Liu L,Macias V,Deaton R,Lacher C,Picklo M,Nonn L,Gann PH,Kajdacsy-Balla A,Prins GS,Freeman VL,Diamond AM

SEPP1 and SEP15 gene polymorphisms and susceptibility to breast cancer.
British journal of biomedical science75(1)36-39(2018 Jan)
Mohammaddoust S,Salehi Z,Saeidi Saedi H

Role of SEP15 Gene Polymorphisms in the Time of Progression to AIDS.
Genetic testing and molecular biomarkers20(7)383-7(2016 Jul)
Benelli JL,de Medeiros RM,Matte MC,de Melo MG,de Matos Almeida SE,Fiegenbaum M

The 811 C/T polymorphism in the 3' untranslated region of the selenoprotein 15-kDa (Sep15) gene and breast cancer in Caucasian women.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(1)1009-15(2016 Jan)
Watrowski R,Castillo-Tong DC,Fabjani G,Schuster E,Fischer M,Zeillinger R

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SELENOF cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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