Gene Symbol | GRAP2 |
Entrez Gene ID | 9402 |
Full Name | GRB2-related adaptor protein 2 |
Synonyms | GADS,GRAP-2,GRB2L,GRBLG,GRID,GRPL,GrbX,Grf40,Mona,P38 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]. |
Disorder MIM: |