COG1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	COG1
Entrez Gene ID	9382
Full Name	component of oligomeric golgi complex 1
Synonyms	CDG2G,LDLB
General protein information	Preferred Names component of oligomeric golgi complex 1 Names conserved oligomeric Golgi complex subunit 1 COG complex subunit 1 conserved oligomeric Golgi complex protein 1 low density lipoprotein receptor defect B complementing
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.1
Summary	The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex. [provided by RefSeq, Jul 2008].
Disorder MIM:	606973
Disorder Html:	Congenital disorder of glycosylation, type IIg, 611209 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_018714.3	NP_061184.1	conserved oligomeric Golgi complex subunit 1
NM_018714.2	NP_061184.1	conserved oligomeric Golgi complex subunit 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cog1	NP_038609.3
Gallus gallus (chicken)	COG1	NP_001025878.2
Danio rerio (zebrafish)	cog1	XP_002661206.3
Xenopus tropicalis (tropical clawed frog)	cog1	XP_002935935.2
Pan troglodytes (chimpanzee)	COG1	XP_003315750.2
	COG1	XP_001086027.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001322	XP_551520.3
Arabidopsis thaliana (thale cress)	AT5G16300	NP_197134.1
Homo sapiens (human)	COG1	NP_061184.1
Bos taurus (cattle)	COG1	NP_001179356.1
Rattus norvegicus (Norway rat)	Cog1	NP_001100532.2
Oryza sativa (rice)	Os01g0777000	NP_001044419.1
Canis lupus familiaris (dog)	COG1	XP_005624227.1
Drosophila melanogaster (fruit fly)	CG4848	NP_650162.1

Gene Ontology
Bibliography

Related articles in PubMed

Oxidative stress and hemoglobin-cholesterol adduct in renal patients with different LDL phenotypes.
Miljkovic M, Kotur-Stevuljevic J, Stefanovic A, Zeljkovic A, Vekic J, Gojkovic T, Bogavac-Stanojevic N, Nikolic M, Simic-Ogrizovic S, Spasojevic-Kalimanovska V, Jelic-Ivanovic Z
International urology and nephrology48(10)1683-90(2016 Oct)

Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.
Dechtawewat T, Paemanee A, Roytrakul S, Songprakhon P, Limjindaporn T, Yenchitsomanus PT, Saitornuang S, Puttikhunt C, Kasinrerk W, Malasit P, Noisakran S
Biochimica et biophysica acta1864(9)1270-1280(2016 09)

Cerebrocostomandibular-like syndrome and a mutation in the conserved oligomeric Golgi complex, subunit 1.
Zeevaert R, Foulquier F, Dimitrov B, Reynders E, Van Damme-Lombaerts R, Simeonov E, Annaert W, Matthijs G, Jaeken J
Human molecular genetics18(3)517-24(2009 Feb)

IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex.
Vasile E, Oka T, Ericsson M, Nakamura N, Krieger M
Experimental cell research312(16)3132-41(2006 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chronic renal patients with more atherogenic lipoprotein LDL B phenotype are in advanced state of oxidative stress compared with control subjects.
Title: Oxidative stress and hemoglobin-cholesterol adduct in renal patients with different LDL phenotypes.

This study reports a novel set of Dengue virus (DENV) NS1-interacting host cell proteins in the HepG2 cell line and proposes possible roles for human NEK2, TAO1, and COG1 in DENV infection.
Title: Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.

A novel mutation in COG1 was found in two patients with a cerebrocostomandibular-like syndrome.
Title: Cerebrocostomandibular-like syndrome and a mutation in the conserved oligomeric Golgi complex, subunit 1.

These findings support the proposal that COG is directly involved in controlling vesicular retrograde transport of Golgi resident proteins throughout the Golgi apparatus.
Title: IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex.

Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp
Title: Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp.

The following COG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17958	NM_018714.3 Latest version!	Homo sapiens component of oligomeric golgi complex 1 (COG1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$657.30 $939.00
View Old Accession Versions >>
OHu17958	NM_018714.2	Homo sapiens component of oligomeric golgi complex 1 (COG1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$657.30 $939.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

COG1 ( NM_018714.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061184.1 Homo sapiens component of oligomeric golgi complex 1 (COG1), mRNA.

Price & Availability↑

CloneID	OHu17958
Clone ID Related Accession (Same CDS sequence)	NM_018714.3 , NM_018714.2
Accession Version	NM_018714.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2943bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC097641.6 and BC021985.2. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_018714.2. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1168264.1, SRR1660805.101027.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000299886.9/ ENSP00000299886.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCACCG CGGCAACCTC ACCCGCGCTG AAGCGGCTGG ATCTGCGCGA CCCTGCGGCT 
CTTTTCGAGA CGCATGGAGC GGAGGAGATC CGCGGGCTGG AGCGCCAGGT TCGGGCCGAG 
ATCGAGCACA AGAAGGAGGA GCTGCGGCAG ATGGTGGGCG AACGGTACCG CGACCTGATC 
GAGGCGGCCG ACACCATCGG CCAGATGCGC CGCTGCGCCG TGGGGCTAGT GGACGCCGTG 
AAGGCCACCG ACCAGTACTG CGCCCGCCTC CGCCAGGCCG GCTCGGCCGC GCCCCGGCCA 
CCGCGGGCCC AGCAGCCACA GCAGCCATCC CAGGAGAAGT TCTACAGCAT GGCTGCCCAG 
ATCAAGCTAC TCTTAGAAAT TCCGGAGAAG ATCTGGAGCT CGATGGAAGC CTCTCAGTGT 
CTCCACGCCA CACAGCTCTA CCTGCTCTGC TGCCACCTCC ACAGCCTGCT CCAGCTGGAT 
TCTTCTAGTT CCCGATACAG TCCCGTCCTC TCCCGGTTTC CTATACTCAT CCGGCAGGTG 
GCAGCCGCCA GCCACTTCCG GTCAACTATT CTGCATGAAA GCAAGATGTT GCTCAAATGC 
CAAGGTGTGT CTGACCAAGC TGTGGCCGAG GCCCTGTGCT CTATAATGCT CTTAGAAGAG 
AGTTCTCCTC GCCAAGCCCT CACAGACTTC CTGCTGGCCA GAAAGGCAAC TATTCAGAAA 
CTTCTCAACC AGCCACACCA TGGTGCTGGT ATCAAGGCTC AGATTTGCTC ATTAGTGGAG 
TTGCTGGCCA CCACTCTGAA GCAAGCTCAT GCCCTTTTCT ACACTTTGCC AGAAGGACTG 
CTGCCAGATC CAGCCCTGCC ATGTGGCTTG CTCTTCTCTA CTCTGGAGAC CATCACAGGC 
CAGCATCCTG CCGGAAAGGG CACTGGTGTC CTGCAGGAAG AGATGAAACT CTGCAGCTGG 
TTTAAACACC TGCCAGCATC CATCGTCGAG TTCCAGCCAA CACTCCGAAC CCTTGCACAT 
CCCATCAGTC AGGAATACCT GAAAGACACG CTGCAGAAAT GGATCCACAT GTGTAATGAA 
GACATTAAAA ATGGGATCAC CAACCTGCTC ATGTACGTGA AGAGCATGAA GGGTCTCGCG 
GGAATCCGGG ACGCCATGTG GGAGTTACTT ACCAATGAGT CCACCAATCA CAGCTGGGAT 
GTGCTATGTC GGCGGCTTCT GGAGAAGCCG CTCTTGTTCT GGGAAGATAT GATGCAGCAA 
CTGTTCCTTG ACCGATTACA GACTCTGACA AAAGAAGGCT TTGACTCCAT CTCCAGTAGC 
TCCAAGGAGC TCTTGGTTTC AGCTTTGCAG GAACTTGAAA GCAGCACCAG CAACTCCCCT 
TCAAATAAGC ACATCCACTT TGAGTACAAC ATGTCGCTCT TCCTCTGGTC TGAGAGTCCT 
AATGACCTGC CTTCCGATGC GGCCTGGGTC AGCGTGGCAA ACCGGGGTCA GTTTGCCAGT 
AGCGGCCTCT CCATGAAAGC ACAAGCCATC AGCCCTTGTG TACAGAACTT CTGTTCTGCC 
CTGGATTCTA AGCTGAAGGT TAAACTAGAT GACCTCCTGG CTTACCTCCC CTCTGATGAC 
TCATCACTGC CCAAGGACGT TTCTCCCACA CAGGCCAAGA GTTCTGCCTT TGACAGATAC 
GCAGATGCGG GGACCGTGCA GGAGATGCTG CGGACTCAGT CCGTGGCATG CATCAAGCAC 
ATCGTGGACT GCATCCGGGC AGAGCTACAG AGCATTGAAG AGGGTGTGCA AGGGCAACAG 
GATGCCCTCA ACAGTGCCAA GCTGCACTCA GTTCTTTTCA TGGCCAGACT CTGCCAGTCC 
CTGGGAGAGC TGTGCCCCCA TCTGAAGCAG TGCATCCTGG GAAAATCAGA GAGCTCAGAG 
AAACCAGCAA GGGAGTTTAG GGCTCTGAGA AAACAGGGAA AGGTGAAAAC TCAGGAAATC 
ATTCCTACAC AGGCCAAGTG GCAAGAGGTT AAAGAAGTAC TCCTCCAGCA GAGCGTGATG 
GGCTACCAGG TCTGGAGCAG TGCAGTTGTG AAAGTTTTGA TTCATGGATT CACCCAGTCA 
TTACTTCTAG ATGATGCTGG CTCAGTTCTG GCCACAGCCA CCAGCTGGGA TGAGCTAGAA 
ATTCAGGAGG AGGCAGAGTC TGGCAGCAGT GTCACATCCA AGATCCGACT CCCTGCACAG 
CCGTCCTGGT ATGTACAGTC CTTCCTGTTT AGTTTATGCC AGGAAATTAA TCGGGTTGGA 
GGCCATGCCT TGCCAAAGGT GACATTACAG GAGATGCTGA AAAGCTGTAT GGTTCAAGTA 
GTAGCTGCCT ATGAGAAACT CTCCGAAGAA AAACAGATTA AGAAAGAAGG TGCATTTCCA 
GTCACCCAGA ACCGGGCGCT GCAGCTGCTT TATGATCTGC GTTACCTCAA CATTGTTCTG 
ACAGCCAAGG GTGACGAGGT GAAGAGTGGC CGGAGCAAGC CAGACTCCAG AATTGAGAAA 
GTGACTGACC ACCTGGAAGC CCTCATTGAT CCATTTGACC TGGACGTTTT CACGCCACAC 
CTCAACAGCA ACCTTCATCG CCTGGTGCAG CGAACTTCTG TTCTGTTTGG ATTGGTGACT 
GGTACAGAGA ATCAGCTCGC CCCCCGGAGC AGTACGTTCA ACTCCCAAGA ACCCCATAAC 
ATCCTGCCAC TGGCATCCAG TCAGATCAGG TTTGGACTTC TCCCACTGAG CATGACAAGC 
ACTCGAAAGG CTAAATCAAC CAGAAACATC GAAACAAAAG CTCAGGTTGT CCCCCCGGCA 
CGCTCCACAG CTGGTGACCC GACAGTTCCT GGCTCCTTGT TCAGACAGCT TGTCAGTGAA 
GAAGACAACA CGTCTGCACC TTCATTATTC AAACTTGGCT GGCTCTCTAG TATGACTAAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061184.1
CDS	16..2958
Translation	MATAATSPALKRLDLRDPAALFETHGAEEIRGLERQVRAEIEHKKEELRQMVGERYRDLIEAADTIGQMRRCAVGLVDAVKATDQYCARLRQAGSAAPRPPRAQQPQQPSQEKFYSMAAQIKLLLEIPEKIWSSMEASQCLHATQLYLLCCHLHSLLQLDSSSSRYSPVLSRFPILIRQVAAASHFRSTILHESKMLLKCQGVSDQAVAEALCSIMLLEESSPRQALTDFLLARKATIQKLLNQPHHGAGIKAQICSLVELLATTLKQAHALFYTLPEGLLPDPALPCGLLFSTLETITGQHPAGKGTGVLQEEMKLCSWFKHLPASIVEFQPTLRTLAHPISQEYLKDTLQKWIHMCNEDIKNGITNLLMYVKSMKGLAGIRDAMWELLTNESTNHSWDVLCRRLLEKPLLFWEDMMQQLFLDRLQTLTKEGFDSISSSSKELLVSALQELESSTSNSPSNKHIHFEYNMSLFLWSESPNDLPSDAAWVSVANRGQFASSGLSMKAQAISPCVQNFCSALDSKLKVKLDDLLAYLPSDDSSLPKDVSPTQAKSSAFDRYADAGTVQEMLRTQSVACIKHIVDCIRAELQSIEEGVQGQQDALNSAKLHSVLFMARLCQSLGELCPHLKQCILGKSESSEKPAREFRALRKQGKVKTQEIIPTQAKWQEVKEVLLQQSVMGYQVWSSAVVKVLIHGFTQSLLLDDAGSVLATATSWDELEIQEEAESGSSVTSKIRLPAQPSWYVQSFLFSLCQEINRVGGHALPKVTLQEMLKSCMVQVVAAYEKLSEEKQIKKEGAFPVTQNRALQLLYDLRYLNIVLTAKGDEVKSGRSKPDSRIEKVTDHLEALIDPFDLDVFTPHLNSNLHRLVQRTSVLFGLVTGTENQLAPRSSTFNSQEPHNILPLASSQIRFGLLPLSMTSTRKAKSTRNIETKAQVVPPARSTAGDPTVPGSLFRQLVSEEDNTSAPSLFKLGWLSSMTK

Target ORF information:

RefSeq Version	NM_018714.3
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 1 (COG1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018714.3

ORF Insert Sequence:

ATGGCCACCG CGGCAACCTC ACCCGCGCTG AAGCGGCTGG ATCTGCGCGA CCCTGCGGCT 
CTTTTCGAGA CGCATGGAGC GGAGGAGATC CGCGGGCTGG AGCGCCAGGT TCGGGCCGAG 
ATCGAGCACA AGAAGGAGGA GCTGCGGCAG ATGGTGGGCG AACGGTACCG CGACCTGATC 
GAGGCGGCCG ACACCATCGG CCAGATGCGC CGCTGCGCCG TGGGGCTAGT GGACGCCGTG 
AAGGCCACCG ACCAGTACTG CGCCCGCCTC CGCCAGGCCG GCTCGGCCGC GCCCCGGCCA 
CCGCGGGCCC AGCAGCCACA GCAGCCATCC CAGGAGAAGT TCTACAGCAT GGCTGCCCAG 
ATCAAGCTAC TCTTAGAAAT TCCGGAGAAG ATCTGGAGCT CGATGGAAGC CTCTCAGTGT 
CTCCACGCCA CACAGCTCTA CCTGCTCTGC TGCCACCTCC ACAGCCTGCT CCAGCTGGAT 
TCTTCTAGTT CCCGATACAG TCCCGTCCTC TCCCGGTTTC CTATACTCAT CCGGCAGGTG 
GCAGCCGCCA GCCACTTCCG GTCAACTATT CTGCATGAAA GCAAGATGTT GCTCAAATGC 
CAAGGTGTGT CTGACCAAGC TGTGGCCGAG GCCCTGTGCT CTATAATGCT CTTAGAAGAG 
AGTTCTCCTC GCCAAGCCCT CACAGACTTC CTGCTGGCCA GAAAGGCAAC TATTCAGAAA 
CTTCTCAACC AGCCACACCA TGGTGCTGGT ATCAAGGCTC AGATTTGCTC ATTAGTGGAG 
TTGCTGGCCA CCACTCTGAA GCAAGCTCAT GCCCTTTTCT ACACTTTGCC AGAAGGACTG 
CTGCCAGATC CAGCCCTGCC ATGTGGCTTG CTCTTCTCTA CTCTGGAGAC CATCACAGGC 
CAGCATCCTG CCGGAAAGGG CACTGGTGTC CTGCAGGAAG AGATGAAACT CTGCAGCTGG 
TTTAAACACC TGCCAGCATC CATCGTCGAG TTCCAGCCAA CACTCCGAAC CCTTGCACAT 
CCCATCAGTC AGGAATACCT GAAAGACACG CTGCAGAAAT GGATCCACAT GTGTAATGAA 
GACATTAAAA ATGGGATCAC CAACCTGCTC ATGTACGTGA AGAGCATGAA GGGTCTCGCG 
GGAATCCGGG ACGCCATGTG GGAGTTACTT ACCAATGAGT CCACCAATCA CAGCTGGGAT 
GTGCTATGTC GGCGGCTTCT GGAGAAGCCG CTCTTGTTCT GGGAAGATAT GATGCAGCAA 
CTGTTCCTTG ACCGATTACA GACTCTGACA AAAGAAGGCT TTGACTCCAT CTCCAGTAGC 
TCCAAGGAGC TCTTGGTTTC AGCTTTGCAG GAACTTGAAA GCAGCACCAG CAACTCCCCT 
TCAAATAAGC ACATCCACTT TGAGTACAAC ATGTCGCTCT TCCTCTGGTC TGAGAGTCCT 
AATGACCTGC CTTCCGATGC GGCCTGGGTC AGCGTGGCAA ACCGGGGTCA GTTTGCCAGT 
AGCGGCCTCT CCATGAAAGC ACAAGCCATC AGCCCTTGTG TACAGAACTT CTGTTCTGCC 
CTGGATTCTA AGCTGAAGGT TAAACTAGAT GACCTCCTGG CTTACCTCCC CTCTGATGAC 
TCATCACTGC CCAAGGACGT TTCTCCCACA CAGGCCAAGA GTTCTGCCTT TGACAGATAC 
GCAGATGCGG GGACCGTGCA GGAGATGCTG CGGACTCAGT CCGTGGCATG CATCAAGCAC 
ATCGTGGACT GCATCCGGGC AGAGCTACAG AGCATTGAAG AGGGTGTGCA AGGGCAACAG 
GATGCCCTCA ACAGTGCCAA GCTGCACTCA GTTCTTTTCA TGGCCAGACT CTGCCAGTCC 
CTGGGAGAGC TGTGCCCCCA TCTGAAGCAG TGCATCCTGG GAAAATCAGA GAGCTCAGAG 
AAACCAGCAA GGGAGTTTAG GGCTCTGAGA AAACAGGGAA AGGTGAAAAC TCAGGAAATC 
ATTCCTACAC AGGCCAAGTG GCAAGAGGTT AAAGAAGTAC TCCTCCAGCA GAGCGTGATG 
GGCTACCAGG TCTGGAGCAG TGCAGTTGTG AAAGTTTTGA TTCATGGATT CACCCAGTCA 
TTACTTCTAG ATGATGCTGG CTCAGTTCTG GCCACAGCCA CCAGCTGGGA TGAGCTAGAA 
ATTCAGGAGG AGGCAGAGTC TGGCAGCAGT GTCACATCCA AGATCCGACT CCCTGCACAG 
CCGTCCTGGT ATGTACAGTC CTTCCTGTTT AGTTTATGCC AGGAAATTAA TCGGGTTGGA 
GGCCATGCCT TGCCAAAGGT GACATTACAG GAGATGCTGA AAAGCTGTAT GGTTCAAGTA 
GTAGCTGCCT ATGAGAAACT CTCCGAAGAA AAACAGATTA AGAAAGAAGG TGCATTTCCA 
GTCACCCAGA ACCGGGCGCT GCAGCTGCTT TATGATCTGC GTTACCTCAA CATTGTTCTG 
ACAGCCAAGG GTGACGAGGT GAAGAGTGGC CGGAGCAAGC CAGACTCCAG AATTGAGAAA 
GTGACTGACC ACCTGGAAGC CCTCATTGAT CCATTTGACC TGGACGTTTT CACGCCACAC 
CTCAACAGCA ACCTTCATCG CCTGGTGCAG CGAACTTCTG TTCTGTTTGG ATTGGTGACT 
GGTACAGAGA ATCAGCTCGC CCCCCGGAGC AGTACGTTCA ACTCCCAAGA ACCCCATAAC 
ATCCTGCCAC TGGCATCCAG TCAGATCAGG TTTGGACTTC TCCCACTGAG CATGACAAGC 
ACTCGAAAGG CTAAATCAAC CAGAAACATC GAAACAAAAG CTCAGGTTGT CCCCCCGGCA 
CGCTCCACAG CTGGTGACCC GACAGTTCCT GGCTCCTTGT TCAGACAGCT TGTCAGTGAA 
GAAGACAACA CGTCTGCACC TTCATTATTC AAACTTGGCT GGCTCTCTAG TATGACTAAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COG1 ( NM_018714.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_061184.1 Homo sapiens component of oligomeric golgi complex 1 (COG1), mRNA.

Price & Availability↑

CloneID	OHu17958
Clone ID Related Accession (Same CDS sequence)	NM_018714.3 , NM_018714.2
Accession Version	NM_018714.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2943bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-08
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC097641.6 and BC021985.2. This sequence is a reference standard in the RefSeqGene project. On Nov 18, 2005 this sequence version replaced NM_018714.1. ##Evidence-Data-START## Transcript exon combination :: BC021985.2, SRR1803613.229421.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCACCG CGGCAACCTC ACCCGCGCTG AAGCGGCTGG ATCTGCGCGA CCCTGCGGCT 
CTTTTCGAGA CGCATGGAGC GGAGGAGATC CGCGGGCTGG AGCGCCAGGT TCGGGCCGAG 
ATCGAGCACA AGAAGGAGGA GCTGCGGCAG ATGGTGGGCG AACGGTACCG CGACCTGATC 
GAGGCGGCCG ACACCATCGG CCAGATGCGC CGCTGCGCCG TGGGGCTAGT GGACGCCGTG 
AAGGCCACCG ACCAGTACTG CGCCCGCCTC CGCCAGGCCG GCTCGGCCGC GCCCCGGCCA 
CCGCGGGCCC AGCAGCCACA GCAGCCATCC CAGGAGAAGT TCTACAGCAT GGCTGCCCAG 
ATCAAGCTAC TCTTAGAAAT TCCGGAGAAG ATCTGGAGCT CGATGGAAGC CTCTCAGTGT 
CTCCACGCCA CACAGCTCTA CCTGCTCTGC TGCCACCTCC ACAGCCTGCT CCAGCTGGAT 
TCTTCTAGTT CCCGATACAG TCCCGTCCTC TCCCGGTTTC CTATACTCAT CCGGCAGGTG 
GCAGCCGCCA GCCACTTCCG GTCAACTATT CTGCATGAAA GCAAGATGTT GCTCAAATGC 
CAAGGTGTGT CTGACCAAGC TGTGGCCGAG GCCCTGTGCT CTATAATGCT CTTAGAAGAG 
AGTTCTCCTC GCCAAGCCCT CACAGACTTC CTGCTGGCCA GAAAGGCAAC TATTCAGAAA 
CTTCTCAACC AGCCACACCA TGGTGCTGGT ATCAAGGCTC AGATTTGCTC ATTAGTGGAG 
TTGCTGGCCA CCACTCTGAA GCAAGCTCAT GCCCTTTTCT ACACTTTGCC AGAAGGACTG 
CTGCCAGATC CAGCCCTGCC ATGTGGCTTG CTCTTCTCTA CTCTGGAGAC CATCACAGGC 
CAGCATCCTG CCGGAAAGGG CACTGGTGTC CTGCAGGAAG AGATGAAACT CTGCAGCTGG 
TTTAAACACC TGCCAGCATC CATCGTCGAG TTCCAGCCAA CACTCCGAAC CCTTGCACAT 
CCCATCAGTC AGGAATACCT GAAAGACACG CTGCAGAAAT GGATCCACAT GTGTAATGAA 
GACATTAAAA ATGGGATCAC CAACCTGCTC ATGTACGTGA AGAGCATGAA GGGTCTCGCG 
GGAATCCGGG ACGCCATGTG GGAGTTACTT ACCAATGAGT CCACCAATCA CAGCTGGGAT 
GTGCTATGTC GGCGGCTTCT GGAGAAGCCG CTCTTGTTCT GGGAAGATAT GATGCAGCAA 
CTGTTCCTTG ACCGATTACA GACTCTGACA AAAGAAGGCT TTGACTCCAT CTCCAGTAGC 
TCCAAGGAGC TCTTGGTTTC AGCTTTGCAG GAACTTGAAA GCAGCACCAG CAACTCCCCT 
TCAAATAAGC ACATCCACTT TGAGTACAAC ATGTCGCTCT TCCTCTGGTC TGAGAGTCCT 
AATGACCTGC CTTCCGATGC GGCCTGGGTC AGCGTGGCAA ACCGGGGTCA GTTTGCCAGT 
AGCGGCCTCT CCATGAAAGC ACAAGCCATC AGCCCTTGTG TACAGAACTT CTGTTCTGCC 
CTGGATTCTA AGCTGAAGGT TAAACTAGAT GACCTCCTGG CTTACCTCCC CTCTGATGAC 
TCATCACTGC CCAAGGACGT TTCTCCCACA CAGGCCAAGA GTTCTGCCTT TGACAGATAC 
GCAGATGCGG GGACCGTGCA GGAGATGCTG CGGACTCAGT CCGTGGCATG CATCAAGCAC 
ATCGTGGACT GCATCCGGGC AGAGCTACAG AGCATTGAAG AGGGTGTGCA AGGGCAACAG 
GATGCCCTCA ACAGTGCCAA GCTGCACTCA GTTCTTTTCA TGGCCAGACT CTGCCAGTCC 
CTGGGAGAGC TGTGCCCCCA TCTGAAGCAG TGCATCCTGG GAAAATCAGA GAGCTCAGAG 
AAACCAGCAA GGGAGTTTAG GGCTCTGAGA AAACAGGGAA AGGTGAAAAC TCAGGAAATC 
ATTCCTACAC AGGCCAAGTG GCAAGAGGTT AAAGAAGTAC TCCTCCAGCA GAGCGTGATG 
GGCTACCAGG TCTGGAGCAG TGCAGTTGTG AAAGTTTTGA TTCATGGATT CACCCAGTCA 
TTACTTCTAG ATGATGCTGG CTCAGTTCTG GCCACAGCCA CCAGCTGGGA TGAGCTAGAA 
ATTCAGGAGG AGGCAGAGTC TGGCAGCAGT GTCACATCCA AGATCCGACT CCCTGCACAG 
CCGTCCTGGT ATGTACAGTC CTTCCTGTTT AGTTTATGCC AGGAAATTAA TCGGGTTGGA 
GGCCATGCCT TGCCAAAGGT GACATTACAG GAGATGCTGA AAAGCTGTAT GGTTCAAGTA 
GTAGCTGCCT ATGAGAAACT CTCCGAAGAA AAACAGATTA AGAAAGAAGG TGCATTTCCA 
GTCACCCAGA ACCGGGCGCT GCAGCTGCTT TATGATCTGC GTTACCTCAA CATTGTTCTG 
ACAGCCAAGG GTGACGAGGT GAAGAGTGGC CGGAGCAAGC CAGACTCCAG AATTGAGAAA 
GTGACTGACC ACCTGGAAGC CCTCATTGAT CCATTTGACC TGGACGTTTT CACGCCACAC 
CTCAACAGCA ACCTTCATCG CCTGGTGCAG CGAACTTCTG TTCTGTTTGG ATTGGTGACT 
GGTACAGAGA ATCAGCTCGC CCCCCGGAGC AGTACGTTCA ACTCCCAAGA ACCCCATAAC 
ATCCTGCCAC TGGCATCCAG TCAGATCAGG TTTGGACTTC TCCCACTGAG CATGACAAGC 
ACTCGAAAGG CTAAATCAAC CAGAAACATC GAAACAAAAG CTCAGGTTGT CCCCCCGGCA 
CGCTCCACAG CTGGTGACCC GACAGTTCCT GGCTCCTTGT TCAGACAGCT TGTCAGTGAA 
GAAGACAACA CGTCTGCACC TTCATTATTC AAACTTGGCT GGCTCTCTAG TATGACTAAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061184.1
CDS	37..2979
Translation	MATAATSPALKRLDLRDPAALFETHGAEEIRGLERQVRAEIEHKKEELRQMVGERYRDLIEAADTIGQMRRCAVGLVDAVKATDQYCARLRQAGSAAPRPPRAQQPQQPSQEKFYSMAAQIKLLLEIPEKIWSSMEASQCLHATQLYLLCCHLHSLLQLDSSSSRYSPVLSRFPILIRQVAAASHFRSTILHESKMLLKCQGVSDQAVAEALCSIMLLEESSPRQALTDFLLARKATIQKLLNQPHHGAGIKAQICSLVELLATTLKQAHALFYTLPEGLLPDPALPCGLLFSTLETITGQHPAGKGTGVLQEEMKLCSWFKHLPASIVEFQPTLRTLAHPISQEYLKDTLQKWIHMCNEDIKNGITNLLMYVKSMKGLAGIRDAMWELLTNESTNHSWDVLCRRLLEKPLLFWEDMMQQLFLDRLQTLTKEGFDSISSSSKELLVSALQELESSTSNSPSNKHIHFEYNMSLFLWSESPNDLPSDAAWVSVANRGQFASSGLSMKAQAISPCVQNFCSALDSKLKVKLDDLLAYLPSDDSSLPKDVSPTQAKSSAFDRYADAGTVQEMLRTQSVACIKHIVDCIRAELQSIEEGVQGQQDALNSAKLHSVLFMARLCQSLGELCPHLKQCILGKSESSEKPAREFRALRKQGKVKTQEIIPTQAKWQEVKEVLLQQSVMGYQVWSSAVVKVLIHGFTQSLLLDDAGSVLATATSWDELEIQEEAESGSSVTSKIRLPAQPSWYVQSFLFSLCQEINRVGGHALPKVTLQEMLKSCMVQVVAAYEKLSEEKQIKKEGAFPVTQNRALQLLYDLRYLNIVLTAKGDEVKSGRSKPDSRIEKVTDHLEALIDPFDLDVFTPHLNSNLHRLVQRTSVLFGLVTGTENQLAPRSSTFNSQEPHNILPLASSQIRFGLLPLSMTSTRKAKSTRNIETKAQVVPPARSTAGDPTVPGSLFRQLVSEEDNTSAPSLFKLGWLSSMTK

Target ORF information:

RefSeq Version	NM_018714.2
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 1 (COG1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018714.2

ORF Insert Sequence:

ATGGCCACCG CGGCAACCTC ACCCGCGCTG AAGCGGCTGG ATCTGCGCGA CCCTGCGGCT 
CTTTTCGAGA CGCATGGAGC GGAGGAGATC CGCGGGCTGG AGCGCCAGGT TCGGGCCGAG 
ATCGAGCACA AGAAGGAGGA GCTGCGGCAG ATGGTGGGCG AACGGTACCG CGACCTGATC 
GAGGCGGCCG ACACCATCGG CCAGATGCGC CGCTGCGCCG TGGGGCTAGT GGACGCCGTG 
AAGGCCACCG ACCAGTACTG CGCCCGCCTC CGCCAGGCCG GCTCGGCCGC GCCCCGGCCA 
CCGCGGGCCC AGCAGCCACA GCAGCCATCC CAGGAGAAGT TCTACAGCAT GGCTGCCCAG 
ATCAAGCTAC TCTTAGAAAT TCCGGAGAAG ATCTGGAGCT CGATGGAAGC CTCTCAGTGT 
CTCCACGCCA CACAGCTCTA CCTGCTCTGC TGCCACCTCC ACAGCCTGCT CCAGCTGGAT 
TCTTCTAGTT CCCGATACAG TCCCGTCCTC TCCCGGTTTC CTATACTCAT CCGGCAGGTG 
GCAGCCGCCA GCCACTTCCG GTCAACTATT CTGCATGAAA GCAAGATGTT GCTCAAATGC 
CAAGGTGTGT CTGACCAAGC TGTGGCCGAG GCCCTGTGCT CTATAATGCT CTTAGAAGAG 
AGTTCTCCTC GCCAAGCCCT CACAGACTTC CTGCTGGCCA GAAAGGCAAC TATTCAGAAA 
CTTCTCAACC AGCCACACCA TGGTGCTGGT ATCAAGGCTC AGATTTGCTC ATTAGTGGAG 
TTGCTGGCCA CCACTCTGAA GCAAGCTCAT GCCCTTTTCT ACACTTTGCC AGAAGGACTG 
CTGCCAGATC CAGCCCTGCC ATGTGGCTTG CTCTTCTCTA CTCTGGAGAC CATCACAGGC 
CAGCATCCTG CCGGAAAGGG CACTGGTGTC CTGCAGGAAG AGATGAAACT CTGCAGCTGG 
TTTAAACACC TGCCAGCATC CATCGTCGAG TTCCAGCCAA CACTCCGAAC CCTTGCACAT 
CCCATCAGTC AGGAATACCT GAAAGACACG CTGCAGAAAT GGATCCACAT GTGTAATGAA 
GACATTAAAA ATGGGATCAC CAACCTGCTC ATGTACGTGA AGAGCATGAA GGGTCTCGCG 
GGAATCCGGG ACGCCATGTG GGAGTTACTT ACCAATGAGT CCACCAATCA CAGCTGGGAT 
GTGCTATGTC GGCGGCTTCT GGAGAAGCCG CTCTTGTTCT GGGAAGATAT GATGCAGCAA 
CTGTTCCTTG ACCGATTACA GACTCTGACA AAAGAAGGCT TTGACTCCAT CTCCAGTAGC 
TCCAAGGAGC TCTTGGTTTC AGCTTTGCAG GAACTTGAAA GCAGCACCAG CAACTCCCCT 
TCAAATAAGC ACATCCACTT TGAGTACAAC ATGTCGCTCT TCCTCTGGTC TGAGAGTCCT 
AATGACCTGC CTTCCGATGC GGCCTGGGTC AGCGTGGCAA ACCGGGGTCA GTTTGCCAGT 
AGCGGCCTCT CCATGAAAGC ACAAGCCATC AGCCCTTGTG TACAGAACTT CTGTTCTGCC 
CTGGATTCTA AGCTGAAGGT TAAACTAGAT GACCTCCTGG CTTACCTCCC CTCTGATGAC 
TCATCACTGC CCAAGGACGT TTCTCCCACA CAGGCCAAGA GTTCTGCCTT TGACAGATAC 
GCAGATGCGG GGACCGTGCA GGAGATGCTG CGGACTCAGT CCGTGGCATG CATCAAGCAC 
ATCGTGGACT GCATCCGGGC AGAGCTACAG AGCATTGAAG AGGGTGTGCA AGGGCAACAG 
GATGCCCTCA ACAGTGCCAA GCTGCACTCA GTTCTTTTCA TGGCCAGACT CTGCCAGTCC 
CTGGGAGAGC TGTGCCCCCA TCTGAAGCAG TGCATCCTGG GAAAATCAGA GAGCTCAGAG 
AAACCAGCAA GGGAGTTTAG GGCTCTGAGA AAACAGGGAA AGGTGAAAAC TCAGGAAATC 
ATTCCTACAC AGGCCAAGTG GCAAGAGGTT AAAGAAGTAC TCCTCCAGCA GAGCGTGATG 
GGCTACCAGG TCTGGAGCAG TGCAGTTGTG AAAGTTTTGA TTCATGGATT CACCCAGTCA 
TTACTTCTAG ATGATGCTGG CTCAGTTCTG GCCACAGCCA CCAGCTGGGA TGAGCTAGAA 
ATTCAGGAGG AGGCAGAGTC TGGCAGCAGT GTCACATCCA AGATCCGACT CCCTGCACAG 
CCGTCCTGGT ATGTACAGTC CTTCCTGTTT AGTTTATGCC AGGAAATTAA TCGGGTTGGA 
GGCCATGCCT TGCCAAAGGT GACATTACAG GAGATGCTGA AAAGCTGTAT GGTTCAAGTA 
GTAGCTGCCT ATGAGAAACT CTCCGAAGAA AAACAGATTA AGAAAGAAGG TGCATTTCCA 
GTCACCCAGA ACCGGGCGCT GCAGCTGCTT TATGATCTGC GTTACCTCAA CATTGTTCTG 
ACAGCCAAGG GTGACGAGGT GAAGAGTGGC CGGAGCAAGC CAGACTCCAG AATTGAGAAA 
GTGACTGACC ACCTGGAAGC CCTCATTGAT CCATTTGACC TGGACGTTTT CACGCCACAC 
CTCAACAGCA ACCTTCATCG CCTGGTGCAG CGAACTTCTG TTCTGTTTGG ATTGGTGACT 
GGTACAGAGA ATCAGCTCGC CCCCCGGAGC AGTACGTTCA ACTCCCAAGA ACCCCATAAC 
ATCCTGCCAC TGGCATCCAG TCAGATCAGG TTTGGACTTC TCCCACTGAG CATGACAAGC 
ACTCGAAAGG CTAAATCAAC CAGAAACATC GAAACAAAAG CTCAGGTTGT CCCCCCGGCA 
CGCTCCACAG CTGGTGACCC GACAGTTCCT GGCTCCTTGT TCAGACAGCT TGTCAGTGAA 
GAAGACAACA CGTCTGCACC TTCATTATTC AAACTTGGCT GGCTCTCTAG TATGACTAAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Oxidative stress and hemoglobin-cholesterol adduct in renal patients with different LDL phenotypes.
International urology and nephrology48(10)1683-90(2016 Oct)
Miljkovic M,Kotur-Stevuljevic J,Stefanovic A,Zeljkovic A,Vekic J,Gojkovic T,Bogavac-Stanojevic N,Nikolic M,Simic-Ogrizovic S,Spasojevic-Kalimanovska V,Jelic-Ivanovic Z

Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.
Biochimica et biophysica acta1864(9)1270-1280(2016 09)
Dechtawewat T,Paemanee A,Roytrakul S,Songprakhon P,Limjindaporn T,Yenchitsomanus PT,Saitornuang S,Puttikhunt C,Kasinrerk W,Malasit P,Noisakran S

Cerebrocostomandibular-like syndrome and a mutation in the conserved oligomeric Golgi complex, subunit 1.
Human molecular genetics18(3)517-24(2009 Feb)
Zeevaert R,Foulquier F,Dimitrov B,Reynders E,Van Damme-Lombaerts R,Simeonov E,Annaert W,Matthijs G,Jaeken J

IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex.
Experimental cell research312(16)3132-41(2006 Oct)
Vasile E,Oka T,Ericsson M,Nakamura N,Krieger M

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COG1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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