CAPZA3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CAPZA3
Entrez Gene ID	93661
Full Name	capping actin protein of muscle Z-line alpha subunit 3
Synonyms	CAPPA3,Gsg3,HEL-S-86
General protein information	Preferred Names capping actin protein of muscle Z-line alpha subunit 3 Names F-actin-capping protein subunit alpha-3 CP-alpha-3 CapZ alpha-3 F-actin capping protein alpha-3 subunit capping protein (actin filament) muscle Z-line, alpha 3 epididymis secretory protein Li 86 germ cell-specific protein 3 testis tissue sperm-binding protein Li 73n
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p12.3
Summary	This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility. [provided by RefSeq, Jul 2008].
Disorder MIM:	608722

mRNA and Protein(s)

mRNA	Protein	Name
NM_033328.3	NP_201585.1	F-actin-capping protein subunit alpha-3
NM_033328.2	NP_201585.1	F-actin-capping protein subunit alpha-3

Pathways from BioSystems

Homologies

Homo sapiens (human)	CAPZA3	NP_201585.1
	CAPZA3	XP_001096292.1
Mus musculus (house mouse)	Capza3	NP_031631.3
Gallus gallus (chicken)	CAPZA3	NP_001265047.1
Canis lupus familiaris (dog)	CAPZA3	XP_534875.1
Bos taurus (cattle)	CAPZA3	NP_001035651.1
Pan troglodytes (chimpanzee)	CAPZA3	NP_001233504.1
Rattus norvegicus (Norway rat)	Capza3	NP_058860.2

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association study of the five-factor model of personality in young Korean women.
Kim HN, Roh SJ, Sung YA, Chung HW, Lee JY, Cho J, Shin H, Kim HL
Journal of human genetics58(10)667-74(2013 Oct)

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, , ,
American journal of human genetics85(5)628-42(2009 Nov)

Molecular cloning and characterization of the human orthologue of male germ cell-specific actin capping protein alpha3 (cpalpha3).
Miyagawa Y, Tanaka H, Iguchi N, Kitamura K, Nakamura Y, Takahashi T, Matsumiya K, Okuyama A, Nishimune Y
Molecular human reproduction8(6)531-9(2002 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

Capping protein alpha3 may play a physiologically important role in sperm architecture as well as in fertility of the human male.
Title: Molecular cloning and characterization of the human orthologue of male germ cell-specific actin capping protein alpha3 (cpalpha3).

The following CAPZA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CAPZA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09322	NM_033328.3 Latest version!	Homo sapiens capping actin protein of muscle Z-line subunit alpha 3 (CAPZA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu09322	NM_033328.2	Homo sapiens capping actin protein of muscle Z-line subunit alpha 3 (CAPZA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CAPZA3 ( NM_033328.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_201585.1 Homo sapiens capping actin protein of muscle Z-line subunit alpha 3 (CAPZA3), mRNA.

Price & Availability↑

CloneID	OHu09322
Clone ID Related Accession (Same CDS sequence)	NM_033328.3 , NM_033328.2
Accession Version	NM_033328.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	F-actin-capping protein subunit alpha-3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG772483.1 and AB053259.1. On May 17, 2019 this sequence version replaced NM_033328.2. ##Evidence-Data-START## Transcript is intronless :: GQ472212.1, BC016745.2 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000317658.5/ ENSP00000326238.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACACTTA GCGTGCTGAG CAGGAAGGAC AAGGAAAGAG TAATTCGCAG ACTGTTATTA 
CAGGCCCCTC CAGGGGAATT TGTAAATGCC TTTGATGATC TCTGTCTGCT TATCCGTGAT 
GAAAAACTTA TGCACCACCA AGGTGAGTGT GCAGGCCACC AACACTGCCA AAAATATTCT 
GTACCACTCT GCATCGATGG AAATCCAGTA CTCTTGTCTC ACCACAATGT AATGGGCGAC 
TACCGATTTT TTGACCATCA AAGCAAACTT TCTTTCAAAT ATGACCTGCT TCAAAATCAG 
CTGAAAGACA TCCAAAGTCA TGGTATCATT CAGAATGAGG CAGAATACCT GAGAGTTGTT 
CTTCTGTGCG CCTTAAAACT GTATGTGAAT GACCACTATC CAAAAGGAAA TTGCAACATG 
CTGAGAAAAA CTGTCAAAAG TAAGGAGTAC TTGATAGCTT GCATTGAAGA TCACAACTAT 
GAAACAGGAG AGTGCTGGAA CGGACTTTGG AAATCTAAAT GGATTTTCCA AGTTAACCCA 
TTTCTAACCC AAGTAACGGG AAGAATATTT GTGCAAGCTC ACTTCTTCAG GTGTGTCAAC 
CTTCATATTG AAATATCCAA GGACCTGAAA GAAAGCTTGG AAATAGTTAA CCAAGCTCAA 
CTGGCTCTAA GTTTTGCAAG GCTTGTGGAA GAGCAAGAGA ACAAATTTCA AGCTGCAGTC 
TTGGAAGAAT TACAGGAGTT ATCCAATGAA GCCCTGAGAA AAATTCTACG AAGGGATCTT 
CCAGTGACCC GCACTCTTAT TGACTGGCAC AGGATACTCT CTGACTTGAA TCTGGTGATG 
TATCCTAAAT TAGGATATGT CATTTATTCA AGAAGTGTGT TGTGCAACTG GATAATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_201585.1
CDS	151..1050
Translation	MTLSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCIDGNPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAEYLRVVLLCALKLYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEALRKILRRDLPVTRTLIDWHRILSDLNLVMYPKLGYVIYSRSVLCNWII

Target ORF information:

RefSeq Version	NM_033328.3
Organism	Homo sapiens(human)
Definition	Homo sapiens capping actin protein of muscle Z-line subunit alpha 3 (CAPZA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033328.3

ORF Insert Sequence:

ATGACACTTA GCGTGCTGAG CAGGAAGGAC AAGGAAAGAG TAATTCGCAG ACTGTTATTA 
CAGGCCCCTC CAGGGGAATT TGTAAATGCC TTTGATGATC TCTGTCTGCT TATCCGTGAT 
GAAAAACTTA TGCACCACCA AGGTGAGTGT GCAGGCCACC AACACTGCCA AAAATATTCT 
GTACCACTCT GCATCGATGG AAATCCAGTA CTCTTGTCTC ACCACAATGT AATGGGCGAC 
TACCGATTTT TTGACCATCA AAGCAAACTT TCTTTCAAAT ATGACCTGCT TCAAAATCAG 
CTGAAAGACA TCCAAAGTCA TGGTATCATT CAGAATGAGG CAGAATACCT GAGAGTTGTT 
CTTCTGTGCG CCTTAAAACT GTATGTGAAT GACCACTATC CAAAAGGAAA TTGCAACATG 
CTGAGAAAAA CTGTCAAAAG TAAGGAGTAC TTGATAGCTT GCATTGAAGA TCACAACTAT 
GAAACAGGAG AGTGCTGGAA CGGACTTTGG AAATCTAAAT GGATTTTCCA AGTTAACCCA 
TTTCTAACCC AAGTAACGGG AAGAATATTT GTGCAAGCTC ACTTCTTCAG GTGTGTCAAC 
CTTCATATTG AAATATCCAA GGACCTGAAA GAAAGCTTGG AAATAGTTAA CCAAGCTCAA 
CTGGCTCTAA GTTTTGCAAG GCTTGTGGAA GAGCAAGAGA ACAAATTTCA AGCTGCAGTC 
TTGGAAGAAT TACAGGAGTT ATCCAATGAA GCCCTGAGAA AAATTCTACG AAGGGATCTT 
CCAGTGACCC GCACTCTTAT TGACTGGCAC AGGATACTCT CTGACTTGAA TCTGGTGATG 
TATCCTAAAT TAGGATATGT CATTTATTCA AGAAGTGTGT TGTGCAACTG GATAATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAPZA3 ( NM_033328.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_201585.1 Homo sapiens capping actin protein of muscle Z-line subunit alpha 3 (CAPZA3), mRNA.

Price & Availability↑

CloneID	OHu09322
Clone ID Related Accession (Same CDS sequence)	NM_033328.3 , NM_033328.2
Accession Version	NM_033328.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	F-actin-capping protein subunit alpha-3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG772483.1 and AB053259.1. On May 13, 2003 this sequence version replaced NM_033328.1. ##Evidence-Data-START## Transcript is intronless :: BC016745.2 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACACTTA GCGTGCTGAG CAGGAAGGAC AAGGAAAGAG TAATTCGCAG ACTGTTATTA 
CAGGCCCCTC CAGGGGAATT TGTAAATGCC TTTGATGATC TCTGTCTGCT TATCCGTGAT 
GAAAAACTTA TGCACCACCA AGGTGAGTGT GCAGGCCACC AACACTGCCA AAAATATTCT 
GTACCACTCT GCATCGATGG AAATCCAGTA CTCTTGTCTC ACCACAATGT AATGGGCGAC 
TACCGATTTT TTGACCATCA AAGCAAACTT TCTTTCAAAT ATGACCTGCT TCAAAATCAG 
CTGAAAGACA TCCAAAGTCA TGGTATCATT CAGAATGAGG CAGAATACCT GAGAGTTGTT 
CTTCTGTGCG CCTTAAAACT GTATGTGAAT GACCACTATC CAAAAGGAAA TTGCAACATG 
CTGAGAAAAA CTGTCAAAAG TAAGGAGTAC TTGATAGCTT GCATTGAAGA TCACAACTAT 
GAAACAGGAG AGTGCTGGAA CGGACTTTGG AAATCTAAAT GGATTTTCCA AGTTAACCCA 
TTTCTAACCC AAGTAACGGG AAGAATATTT GTGCAAGCTC ACTTCTTCAG GTGTGTCAAC 
CTTCATATTG AAATATCCAA GGACCTGAAA GAAAGCTTGG AAATAGTTAA CCAAGCTCAA 
CTGGCTCTAA GTTTTGCAAG GCTTGTGGAA GAGCAAGAGA ACAAATTTCA AGCTGCAGTC 
TTGGAAGAAT TACAGGAGTT ATCCAATGAA GCCCTGAGAA AAATTCTACG AAGGGATCTT 
CCAGTGACCC GCACTCTTAT TGACTGGCAC AGGATACTCT CTGACTTGAA TCTGGTGATG 
TATCCTAAAT TAGGATATGT CATTTATTCA AGAAGTGTGT TGTGCAACTG GATAATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_201585.1
CDS	159..1058
Translation	MTLSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCIDGNPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAEYLRVVLLCALKLYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEALRKILRRDLPVTRTLIDWHRILSDLNLVMYPKLGYVIYSRSVLCNWII

Target ORF information:

RefSeq Version	NM_033328.2
Organism	Homo sapiens(human)
Definition	Homo sapiens capping actin protein of muscle Z-line subunit alpha 3 (CAPZA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033328.2

ORF Insert Sequence:

ATGACACTTA GCGTGCTGAG CAGGAAGGAC AAGGAAAGAG TAATTCGCAG ACTGTTATTA 
CAGGCCCCTC CAGGGGAATT TGTAAATGCC TTTGATGATC TCTGTCTGCT TATCCGTGAT 
GAAAAACTTA TGCACCACCA AGGTGAGTGT GCAGGCCACC AACACTGCCA AAAATATTCT 
GTACCACTCT GCATCGATGG AAATCCAGTA CTCTTGTCTC ACCACAATGT AATGGGCGAC 
TACCGATTTT TTGACCATCA AAGCAAACTT TCTTTCAAAT ATGACCTGCT TCAAAATCAG 
CTGAAAGACA TCCAAAGTCA TGGTATCATT CAGAATGAGG CAGAATACCT GAGAGTTGTT 
CTTCTGTGCG CCTTAAAACT GTATGTGAAT GACCACTATC CAAAAGGAAA TTGCAACATG 
CTGAGAAAAA CTGTCAAAAG TAAGGAGTAC TTGATAGCTT GCATTGAAGA TCACAACTAT 
GAAACAGGAG AGTGCTGGAA CGGACTTTGG AAATCTAAAT GGATTTTCCA AGTTAACCCA 
TTTCTAACCC AAGTAACGGG AAGAATATTT GTGCAAGCTC ACTTCTTCAG GTGTGTCAAC 
CTTCATATTG AAATATCCAA GGACCTGAAA GAAAGCTTGG AAATAGTTAA CCAAGCTCAA 
CTGGCTCTAA GTTTTGCAAG GCTTGTGGAA GAGCAAGAGA ACAAATTTCA AGCTGCAGTC 
TTGGAAGAAT TACAGGAGTT ATCCAATGAA GCCCTGAGAA AAATTCTACG AAGGGATCTT 
CCAGTGACCC GCACTCTTAT TGACTGGCAC AGGATACTCT CTGACTTGAA TCTGGTGATG 
TATCCTAAAT TAGGATATGT CATTTATTCA AGAAGTGTGT TGTGCAACTG GATAATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association study of the five-factor model of personality in young Korean women.
Journal of human genetics58(10)667-74(2013 Oct)
Kim HN,Roh SJ,Sung YA,Chung HW,Lee JY,Cho J,Shin H,Kim HL

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballesc? JL,Oliva R

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics85(5)628-42(2009 Nov)
Talmud PJ,Drenos F,Shah S,Shah T,Palmen J,Verzilli C,Gaunt TR,Pallas J,Lovering R,Li K,Casas JP,Sofat R,Kumari M,Rodriguez S,Johnson T,Newhouse SJ,Dominiczak A,Samani NJ,Caulfield M,Sever P,Stanton A,Shields DC,Padmanabhan S,Melander O,Hastie C,Delles C,Ebrahim S,Marmot MG,Smith GD,Lawlor DA,Munroe PB,Day IN,Kivimaki M,Whittaker J,Humphries SE,Hingorani AD,,,

Molecular cloning and characterization of the human orthologue of male germ cell-specific actin capping protein alpha3 (cpalpha3).
Molecular human reproduction8(6)531-9(2002 Jun)
Miyagawa Y,Tanaka H,Iguchi N,Kitamura K,Nakamura Y,Takahashi T,Matsumiya K,Okuyama A,Nishimune Y

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

CAPZA3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報