TGM5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TGM5
Entrez Gene ID	9333
Full Name	transglutaminase 5
Synonyms	PSS2,TGASE5,TGASEX,TGM6,TGMX,TGX
General protein information	Preferred Names transglutaminase 5 Names protein-glutamine gamma-glutamyltransferase 5 TG(X) TGase X TGase-5 transglutaminase V transglutaminase X
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q15.2
Summary	This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009].
Disorder MIM:	603805
Disorder Html:	Peeling skin syndrome 2, 609796 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_004245.3	NP_004236.1	protein-glutamine gamma-glutamyltransferase 5 isoform 2
NM_201631.3	NP_963925.2	protein-glutamine gamma-glutamyltransferase 5 isoform 1
XM_017022729.1	XP_016878218.1	protein-glutamine gamma-glutamyltransferase 5 isoform X1
NM_004245.4	NP_004236.1	protein-glutamine gamma-glutamyltransferase 5 isoform 2
XM_011522230.2	XP_011520532.1	protein-glutamine gamma-glutamyltransferase 5 isoform X1
NM_201631.4	NP_963925.2	protein-glutamine gamma-glutamyltransferase 5 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TGM5	NP_963925.2
Pan troglodytes (chimpanzee)	TGM5	XP_001157235.1
Canis lupus familiaris (dog)	TGM5	XP_005638381.1
Rattus norvegicus (Norway rat)	LOC691932	XP_003749611.1
Xenopus tropicalis (tropical clawed frog)	tgm5	XP_002935579.2
	TGM5	XP_001101645.1
Bos taurus (cattle)	TGM5	NP_001095479.1
Mus musculus (house mouse)	Tgm5	NP_083075.1

Gene Ontology
Bibliography

Related articles in PubMed

Acral peeling skin syndrome resulting from mutations in TGM5.
Ca?ueto J, Bueno E, Rodr?guez-Diaz E, Vicente-D?az MA, ?lvarez-Cuesta CC, Gonzalvo-Rodr?guez P, Gonz?lez-Sarmiento R
Journal of the European Academy of Dermatology and Venereology : JEADV30(3)477-80(2016 Mar)

Novel TGM5 mutations in acral peeling skin syndrome.
van der Velden JJ, van Geel M, Nellen RG, Jonkman MF, McGrath JA, Nanda A, Sprecher E, van Steensel MA, McLean WH, Cassidy AJ
Experimental dermatology24(4)285-9(2015 Apr)

Under-recognition of acral peeling skin syndrome: 59 new cases with 15 novel mutations.
Szczecinska W, Nesteruk D, Wertheim-Tysarowska K, Greenblatt DT, Baty D, Browne F, Liu L, Ozoemena L, Terron-Kwiatkowski A, McGrath JA, Mellerio JE, Morton J, Wo?niak K, Kowalewski C, Has C, Moss C
The British journal of dermatology171(5)1206-10(2014 Nov)

A missense mutation in TGM5 causes acral peeling skin syndrome in a Tunisian family.
Kharfi M, El Fekih N, Ammar D, Jaafoura H, Schwonbeck S, van Steensel MA, Fazaa B, Kamoun MR, Fischer J
The Journal of investigative dermatology129(10)2512-5(2009 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Acral PSS (APSS) (OMIM 609796), typically non-inflammatory, is confined to distal extremities with localized exfoliation of the epidermis. It is caused by mutations in the TGM5 gene, encoding transglutaminase 5[3] or in the CTSA gene, encoding cystatin A and it is inherited in autosomal recessive pattern
Title: Acral peeling skin syndrome resulting from mutations in TGM5.

We report both European and non-European families with acral peeling skin syndrome carrying mutations in the TGM5 gene. In 5 patients, we found 3 novel mutations: c.1001+2_1001+3del, c.1171G>A and c.1498C>T.
Title: Novel TGM5 mutations in acral peeling skin syndrome.

Data trebles the number of TMG5 mutations and provides further evidence that pCly113Cys is a founder mutation in the European population.
Title: Under-recognition of acral peeling skin syndrome: 59 new cases with 15 novel mutations.

study concludes polymorphisms of TGM5, PPAP2B and PSMA4 are not major contributors tonon-small cell lung cancer susceptibility in never-smoking hinese population, this primarily can be attributed to the significantly distinct genetic background of Asian populations from western populations
Title: Association between TGM5, PPAP2B and PSMA4 polymorphisms and NSCLC in never-smoking Chinese population.

Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.
Title: Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.

The following TGM5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGM5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22662	NM_201631.4 Latest version!	Homo sapiens transglutaminase 5 (TGM5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$510.30 $729.00
OHu62701	XM_017022729.1 Latest version!	Homo sapiens transglutaminase 5 (TGM5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu62701	XM_011522230.2 Latest version!	Homo sapiens transglutaminase 5 (TGM5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu01390	NM_004245.4 Latest version!	Homo sapiens transglutaminase 5 (TGM5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu01390	NM_004245.3	Homo sapiens transglutaminase 5 (TGM5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu22662	NM_201631.3	Homo sapiens transglutaminase 5 (TGM5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$510.30 $729.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TGM5 ( NM_201631.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_963925.2 Homo sapiens transglutaminase 5 (TGM5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22662
Clone ID Related Accession (Same CDS sequence)	NM_201631.3 , NM_201631.4
Accession Version	NM_201631.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC119009.1, AK298479.1, AC068724.7, AW467571.1 and CA314704.1. This sequence is a reference standard in the RefSeqGene project. On Nov 4, 2009 this sequence version replaced NM_201631.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC119009.1, AF035960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAAG GGCTAGAAGT GGCCCTCACA GACCTCCAGA GCTCCAGAAA TAATGTGCGG 
CACCACACGG AGGAGATCAC TGTGGACCAC CTGCTTGTTC GCCGGGGCCA GGCCTTCAAC 
CTCACCCTGT ACTTCAGGAA CCGGAGCTTC CAGCCAGGCC TGGACAACAT CATCTTCGTG 
GTTGAAACTG GACCGCTGCC AGACCTGGCC TTGGGGACTC GGGCTGTGTT CAGCCTGGCA 
CGCCATCACA GCCCCAGCCC CTGGATTGCC TGGCTGGAGA CCAATGGGGC CACCTCCACA 
GAGGTGAGCT TGTGCGCTCC TCCCACGGCG GCCGTGGGTC GGTACCTCTT GAAAATCCAC 
ATCGACTCCT TCCAGGGGTC TGTGACGGCC TACCAGCTAG GGGAGTTCAT CCTGCTTTTC 
AATCCCTGGT GCCCAGAGGA TGCTGTCTAC TTGGACAGTG AACCCCAGAG GCAGGAGTAT 
GTCATGAATG ATTATGGCTT CATCTACCAA GGCAGCAAGA ACTGGATCCG CCCATGTCCC 
TGGAACTATG GACAGTTTGA AGACAAAATC ATAGACATCT GCCTGAAGCT GCTAGACAAG 
AGCCTGCACT TCCAGACTGA CCCAGCCACA GACTGTGCTC TGCGGGGAAG CCCCGTCTAC 
GTCAGCAGAG TGGTGTGTGC CATGATCAAC AGCAATGATG ATAATGGGGT GCTCAATGGA 
AACTGGAGTG AGAATTACAC AGACGGCGCC AACCCTGCGG AGTGGACGGG CAGCGTGGCC 
ATCCTGAAGC AGTGGAACGC CACAGGCTGC CAGCCCGTGC GCTACGGGCA ATGCTGGGTC 
TTTGCTGCCG TCATGTGCAC AGTGATGAGG TGTCTGGGGA TCCCTACCCG TGTGATCACC 
AACTTCGACT CTGGCCACGA TACAGATGGA AACCTGATCA TAGATGAGTA TTATGACAAC 
ACAGGCAGGA TTTTGGGGAA TAAGAAGAAG GATACTATCT GGAACTTCCA TGTCTGGAAT 
GAGTGCTGGA TGGCCCGGAA GGATCTGCCC CCTGCATATG GAGGCTGGCA GGTGCTGGAC 
GCCACACCTC AGGAGATGAG CAACGGCGTC TACTGCTGTG GCCCTGCCTC TGTCAGAGCC 
ATCAAAGAAG GAGAAGTGGA CCTGAACTAT GACACGCCCT TTGTGTTTTC GATGGTGAAT 
GCTGACTGCA TGTCCTGGCT CGTCCAGGGA GGGAAGGAGC AGAAGCTTCA CCAGGACACG 
AGTTCTGTTG GCAATTTTAT CAGCACAAAG AGCATCCAGA GTGACGAGCG GGATGACATC 
ACAGAGAACT ACAAGTATGA AGAAGGATCC CTCCAGGAGA GGCAGGTGTT TCTGAAGGCT 
CTGCAGAAGC TGAAGGCTAG AAGCTTCCAT GGCTCCCAAA GAGGAGCAGA GTTGCAACCT 
TCCAGGCCCA CATCACTGAG CCAGGACAGC CCTCGGAGCC TGCATACACC TTCCCTTCGA 
CCCAGTGATG TGGTGCAAGT CTCCCTGAAA TTCAAGCTGC TCGACCCGCC CAACATGGGC 
CAGGATATAT GCTTTGTCCT GCTGGCCCTC AACATGTCCT CCCAGTTCAA GGACCTCAAA 
GTGAACCTGA GTGCCCAGTC TCTGCTGCAC GATGGCAGCC CCCTGTCCCC ATTCTGGCAG 
GACACAGCGT TCATCACACT CTCTCCTAAA GAAGCAAAGA CCTACCCCTG CAAAATCTCC 
TATTCCCAGT ACAGCCAGTA CCTGTCAACA GACAAGCTGA TCCGCATCAG TGCCCTGGGT 
GAAGAGAAAA GCAGTCCTGA GAAAATCCTG GTGAACAAGA TCATCACCTT ATCTTATCCA 
AGCATCACGA TTAATGTTCT AGGAGCAGCC GTTGTGAACC AGCCACTCTC CATACAGGTG 
ATATTTTCAA ACCCCCTCTC GGAGCAGGTT GAGGACTGTG TGCTGACTGT GGAAGGAAGT 
GGCCTCTTCA AGAAACAGCA GAAAGTCTTC CTTGGAGTCC TCAAACCCCA ACACCAAGCA 
AGCATCATTC TGGAGACCGT CCCCTTCAAG AGTGGACAAA GGCAGATCCA AGCTAATATG 
AGAAGCAACA AGTTTAAGGA CATTAAGGGT TACAGGAATG TTTATGTAGA CTTTGCATTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_963925.2
CDS	9..2171
Translation	MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVETGPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHIDSFQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL

Target ORF information:

RefSeq Version	NM_201631.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 5 (TGM5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201631.3

ORF Insert Sequence:

ATGGCCCAAG GGCTAGAAGT GGCCCTCACA GACCTCCAGA GCTCCAGAAA TAATGTGCGG 
CACCACACGG AGGAGATCAC TGTGGACCAC CTGCTTGTTC GCCGGGGCCA GGCCTTCAAC 
CTCACCCTGT ACTTCAGGAA CCGGAGCTTC CAGCCAGGCC TGGACAACAT CATCTTCGTG 
GTTGAAACTG GACCGCTGCC AGACCTGGCC TTGGGGACTC GGGCTGTGTT CAGCCTGGCA 
CGCCATCACA GCCCCAGCCC CTGGATTGCC TGGCTGGAGA CCAATGGGGC CACCTCCACA 
GAGGTGAGCT TGTGCGCTCC TCCCACGGCG GCCGTGGGTC GGTACCTCTT GAAAATCCAC 
ATCGACTCCT TCCAGGGGTC TGTGACGGCC TACCAGCTAG GGGAGTTCAT CCTGCTTTTC 
AATCCCTGGT GCCCAGAGGA TGCTGTCTAC TTGGACAGTG AACCCCAGAG GCAGGAGTAT 
GTCATGAATG ATTATGGCTT CATCTACCAA GGCAGCAAGA ACTGGATCCG CCCATGTCCC 
TGGAACTATG GACAGTTTGA AGACAAAATC ATAGACATCT GCCTGAAGCT GCTAGACAAG 
AGCCTGCACT TCCAGACTGA CCCAGCCACA GACTGTGCTC TGCGGGGAAG CCCCGTCTAC 
GTCAGCAGAG TGGTGTGTGC CATGATCAAC AGCAATGATG ATAATGGGGT GCTCAATGGA 
AACTGGAGTG AGAATTACAC AGACGGCGCC AACCCTGCGG AGTGGACGGG CAGCGTGGCC 
ATCCTGAAGC AGTGGAACGC CACAGGCTGC CAGCCCGTGC GCTACGGGCA ATGCTGGGTC 
TTTGCTGCCG TCATGTGCAC AGTGATGAGG TGTCTGGGGA TCCCTACCCG TGTGATCACC 
AACTTCGACT CTGGCCACGA TACAGATGGA AACCTGATCA TAGATGAGTA TTATGACAAC 
ACAGGCAGGA TTTTGGGGAA TAAGAAGAAG GATACTATCT GGAACTTCCA TGTCTGGAAT 
GAGTGCTGGA TGGCCCGGAA GGATCTGCCC CCTGCATATG GAGGCTGGCA GGTGCTGGAC 
GCCACACCTC AGGAGATGAG CAACGGCGTC TACTGCTGTG GCCCTGCCTC TGTCAGAGCC 
ATCAAAGAAG GAGAAGTGGA CCTGAACTAT GACACGCCCT TTGTGTTTTC GATGGTGAAT 
GCTGACTGCA TGTCCTGGCT CGTCCAGGGA GGGAAGGAGC AGAAGCTTCA CCAGGACACG 
AGTTCTGTTG GCAATTTTAT CAGCACAAAG AGCATCCAGA GTGACGAGCG GGATGACATC 
ACAGAGAACT ACAAGTATGA AGAAGGATCC CTCCAGGAGA GGCAGGTGTT TCTGAAGGCT 
CTGCAGAAGC TGAAGGCTAG AAGCTTCCAT GGCTCCCAAA GAGGAGCAGA GTTGCAACCT 
TCCAGGCCCA CATCACTGAG CCAGGACAGC CCTCGGAGCC TGCATACACC TTCCCTTCGA 
CCCAGTGATG TGGTGCAAGT CTCCCTGAAA TTCAAGCTGC TCGACCCGCC CAACATGGGC 
CAGGATATAT GCTTTGTCCT GCTGGCCCTC AACATGTCCT CCCAGTTCAA GGACCTCAAA 
GTGAACCTGA GTGCCCAGTC TCTGCTGCAC GATGGCAGCC CCCTGTCCCC ATTCTGGCAG 
GACACAGCGT TCATCACACT CTCTCCTAAA GAAGCAAAGA CCTACCCCTG CAAAATCTCC 
TATTCCCAGT ACAGCCAGTA CCTGTCAACA GACAAGCTGA TCCGCATCAG TGCCCTGGGT 
GAAGAGAAAA GCAGTCCTGA GAAAATCCTG GTGAACAAGA TCATCACCTT ATCTTATCCA 
AGCATCACGA TTAATGTTCT AGGAGCAGCC GTTGTGAACC AGCCACTCTC CATACAGGTG 
ATATTTTCAA ACCCCCTCTC GGAGCAGGTT GAGGACTGTG TGCTGACTGT GGAAGGAAGT 
GGCCTCTTCA AGAAACAGCA GAAAGTCTTC CTTGGAGTCC TCAAACCCCA ACACCAAGCA 
AGCATCATTC TGGAGACCGT CCCCTTCAAG AGTGGACAAA GGCAGATCCA AGCTAATATG 
AGAAGCAACA AGTTTAAGGA CATTAAGGGT TACAGGAATG TTTATGTAGA CTTTGCATTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TGM5 ( NM_201631.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_963925.2 Homo sapiens transglutaminase 5 (TGM5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22662
Clone ID Related Accession (Same CDS sequence)	NM_201631.3 , NM_201631.4
Accession Version	NM_201631.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009852.9, BC119009.1, AK298479.1, AC068724.7, AW467571.1 and CA314704.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_201631.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC119009.1, AF035960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000220420.10/ ENSP00000220420.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAAG GGCTAGAAGT GGCCCTCACA GACCTCCAGA GCTCCAGAAA TAATGTGCGG 
CACCACACGG AGGAGATCAC TGTGGACCAC CTGCTTGTTC GCCGGGGCCA GGCCTTCAAC 
CTCACCCTGT ACTTCAGGAA CCGGAGCTTC CAGCCAGGCC TGGACAACAT CATCTTCGTG 
GTTGAAACTG GACCGCTGCC AGACCTGGCC TTGGGGACTC GGGCTGTGTT CAGCCTGGCA 
CGCCATCACA GCCCCAGCCC CTGGATTGCC TGGCTGGAGA CCAATGGGGC CACCTCCACA 
GAGGTGAGCT TGTGCGCTCC TCCCACGGCG GCCGTGGGTC GGTACCTCTT GAAAATCCAC 
ATCGACTCCT TCCAGGGGTC TGTGACGGCC TACCAGCTAG GGGAGTTCAT CCTGCTTTTC 
AATCCCTGGT GCCCAGAGGA TGCTGTCTAC TTGGACAGTG AACCCCAGAG GCAGGAGTAT 
GTCATGAATG ATTATGGCTT CATCTACCAA GGCAGCAAGA ACTGGATCCG CCCATGTCCC 
TGGAACTATG GACAGTTTGA AGACAAAATC ATAGACATCT GCCTGAAGCT GCTAGACAAG 
AGCCTGCACT TCCAGACTGA CCCAGCCACA GACTGTGCTC TGCGGGGAAG CCCCGTCTAC 
GTCAGCAGAG TGGTGTGTGC CATGATCAAC AGCAATGATG ATAATGGGGT GCTCAATGGA 
AACTGGAGTG AGAATTACAC AGACGGCGCC AACCCTGCGG AGTGGACGGG CAGCGTGGCC 
ATCCTGAAGC AGTGGAACGC CACAGGCTGC CAGCCCGTGC GCTACGGGCA ATGCTGGGTC 
TTTGCTGCCG TCATGTGCAC AGTGATGAGG TGTCTGGGGA TCCCTACCCG TGTGATCACC 
AACTTCGACT CTGGCCACGA TACAGATGGA AACCTGATCA TAGATGAGTA TTATGACAAC 
ACAGGCAGGA TTTTGGGGAA TAAGAAGAAG GATACTATCT GGAACTTCCA TGTCTGGAAT 
GAGTGCTGGA TGGCCCGGAA GGATCTGCCC CCTGCATATG GAGGCTGGCA GGTGCTGGAC 
GCCACACCTC AGGAGATGAG CAACGGCGTC TACTGCTGTG GCCCTGCCTC TGTCAGAGCC 
ATCAAAGAAG GAGAAGTGGA CCTGAACTAT GACACGCCCT TTGTGTTTTC GATGGTGAAT 
GCTGACTGCA TGTCCTGGCT CGTCCAGGGA GGGAAGGAGC AGAAGCTTCA CCAGGACACG 
AGTTCTGTTG GCAATTTTAT CAGCACAAAG AGCATCCAGA GTGACGAGCG GGATGACATC 
ACAGAGAACT ACAAGTATGA AGAAGGATCC CTCCAGGAGA GGCAGGTGTT TCTGAAGGCT 
CTGCAGAAGC TGAAGGCTAG AAGCTTCCAT GGCTCCCAAA GAGGAGCAGA GTTGCAACCT 
TCCAGGCCCA CATCACTGAG CCAGGACAGC CCTCGGAGCC TGCATACACC TTCCCTTCGA 
CCCAGTGATG TGGTGCAAGT CTCCCTGAAA TTCAAGCTGC TCGACCCGCC CAACATGGGC 
CAGGATATAT GCTTTGTCCT GCTGGCCCTC AACATGTCCT CCCAGTTCAA GGACCTCAAA 
GTGAACCTGA GTGCCCAGTC TCTGCTGCAC GATGGCAGCC CCCTGTCCCC ATTCTGGCAG 
GACACAGCGT TCATCACACT CTCTCCTAAA GAAGCAAAGA CCTACCCCTG CAAAATCTCC 
TATTCCCAGT ACAGCCAGTA CCTGTCAACA GACAAGCTGA TCCGCATCAG TGCCCTGGGT 
GAAGAGAAAA GCAGTCCTGA GAAAATCCTG GTGAACAAGA TCATCACCTT ATCTTATCCA 
AGCATCACGA TTAATGTTCT AGGAGCAGCC GTTGTGAACC AGCCACTCTC CATACAGGTG 
ATATTTTCAA ACCCCCTCTC GGAGCAGGTT GAGGACTGTG TGCTGACTGT GGAAGGAAGT 
GGCCTCTTCA AGAAACAGCA GAAAGTCTTC CTTGGAGTCC TCAAACCCCA ACACCAAGCA 
AGCATCATTC TGGAGACCGT CCCCTTCAAG AGTGGACAAA GGCAGATCCA AGCTAATATG 
AGAAGCAACA AGTTTAAGGA CATTAAGGGT TACAGGAATG TTTATGTAGA CTTTGCATTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_963925.2
CDS	80..2242
Translation	MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVETGPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHIDSFQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL

Target ORF information:

RefSeq Version	NM_201631.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 5 (TGM5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201631.4

ORF Insert Sequence:

ATGGCCCAAG GGCTAGAAGT GGCCCTCACA GACCTCCAGA GCTCCAGAAA TAATGTGCGG 
CACCACACGG AGGAGATCAC TGTGGACCAC CTGCTTGTTC GCCGGGGCCA GGCCTTCAAC 
CTCACCCTGT ACTTCAGGAA CCGGAGCTTC CAGCCAGGCC TGGACAACAT CATCTTCGTG 
GTTGAAACTG GACCGCTGCC AGACCTGGCC TTGGGGACTC GGGCTGTGTT CAGCCTGGCA 
CGCCATCACA GCCCCAGCCC CTGGATTGCC TGGCTGGAGA CCAATGGGGC CACCTCCACA 
GAGGTGAGCT TGTGCGCTCC TCCCACGGCG GCCGTGGGTC GGTACCTCTT GAAAATCCAC 
ATCGACTCCT TCCAGGGGTC TGTGACGGCC TACCAGCTAG GGGAGTTCAT CCTGCTTTTC 
AATCCCTGGT GCCCAGAGGA TGCTGTCTAC TTGGACAGTG AACCCCAGAG GCAGGAGTAT 
GTCATGAATG ATTATGGCTT CATCTACCAA GGCAGCAAGA ACTGGATCCG CCCATGTCCC 
TGGAACTATG GACAGTTTGA AGACAAAATC ATAGACATCT GCCTGAAGCT GCTAGACAAG 
AGCCTGCACT TCCAGACTGA CCCAGCCACA GACTGTGCTC TGCGGGGAAG CCCCGTCTAC 
GTCAGCAGAG TGGTGTGTGC CATGATCAAC AGCAATGATG ATAATGGGGT GCTCAATGGA 
AACTGGAGTG AGAATTACAC AGACGGCGCC AACCCTGCGG AGTGGACGGG CAGCGTGGCC 
ATCCTGAAGC AGTGGAACGC CACAGGCTGC CAGCCCGTGC GCTACGGGCA ATGCTGGGTC 
TTTGCTGCCG TCATGTGCAC AGTGATGAGG TGTCTGGGGA TCCCTACCCG TGTGATCACC 
AACTTCGACT CTGGCCACGA TACAGATGGA AACCTGATCA TAGATGAGTA TTATGACAAC 
ACAGGCAGGA TTTTGGGGAA TAAGAAGAAG GATACTATCT GGAACTTCCA TGTCTGGAAT 
GAGTGCTGGA TGGCCCGGAA GGATCTGCCC CCTGCATATG GAGGCTGGCA GGTGCTGGAC 
GCCACACCTC AGGAGATGAG CAACGGCGTC TACTGCTGTG GCCCTGCCTC TGTCAGAGCC 
ATCAAAGAAG GAGAAGTGGA CCTGAACTAT GACACGCCCT TTGTGTTTTC GATGGTGAAT 
GCTGACTGCA TGTCCTGGCT CGTCCAGGGA GGGAAGGAGC AGAAGCTTCA CCAGGACACG 
AGTTCTGTTG GCAATTTTAT CAGCACAAAG AGCATCCAGA GTGACGAGCG GGATGACATC 
ACAGAGAACT ACAAGTATGA AGAAGGATCC CTCCAGGAGA GGCAGGTGTT TCTGAAGGCT 
CTGCAGAAGC TGAAGGCTAG AAGCTTCCAT GGCTCCCAAA GAGGAGCAGA GTTGCAACCT 
TCCAGGCCCA CATCACTGAG CCAGGACAGC CCTCGGAGCC TGCATACACC TTCCCTTCGA 
CCCAGTGATG TGGTGCAAGT CTCCCTGAAA TTCAAGCTGC TCGACCCGCC CAACATGGGC 
CAGGATATAT GCTTTGTCCT GCTGGCCCTC AACATGTCCT CCCAGTTCAA GGACCTCAAA 
GTGAACCTGA GTGCCCAGTC TCTGCTGCAC GATGGCAGCC CCCTGTCCCC ATTCTGGCAG 
GACACAGCGT TCATCACACT CTCTCCTAAA GAAGCAAAGA CCTACCCCTG CAAAATCTCC 
TATTCCCAGT ACAGCCAGTA CCTGTCAACA GACAAGCTGA TCCGCATCAG TGCCCTGGGT 
GAAGAGAAAA GCAGTCCTGA GAAAATCCTG GTGAACAAGA TCATCACCTT ATCTTATCCA 
AGCATCACGA TTAATGTTCT AGGAGCAGCC GTTGTGAACC AGCCACTCTC CATACAGGTG 
ATATTTTCAA ACCCCCTCTC GGAGCAGGTT GAGGACTGTG TGCTGACTGT GGAAGGAAGT 
GGCCTCTTCA AGAAACAGCA GAAAGTCTTC CTTGGAGTCC TCAAACCCCA ACACCAAGCA 
AGCATCATTC TGGAGACCGT CCCCTTCAAG AGTGGACAAA GGCAGATCCA AGCTAATATG 
AGAAGCAACA AGTTTAAGGA CATTAAGGGT TACAGGAATG TTTATGTAGA CTTTGCATTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TGM5 ( XM_017022729.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016878218.1 Homo sapiens transglutaminase 5 (TGM5), transcript variant X2, mRNA.

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CloneID	OHu62701
Clone ID Related Accession (Same CDS sequence)	XM_017022729.1 , XM_011522230.2
Accession Version	XM_017022729.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCGGA AGGATCTGCC CCCTGCATAT GGAGGCTGGC AGGTGCTGGA CGCCACACCT 
CAGGAGATGA GCAACGGCGT CTACTGCTGT GGCCCTGCCT CTGTCAGAGC CATCAAAGAA 
GGAGAAGTGG ACCTGAACTA TGACACGCCC TTTGTGTTTT CGATGGTGAA TGCTGACTGC 
ATGTCCTGGC TCGTCCAGGG AGGGAAGGAG CAGAAGCTTC ACCAGGACAC GAGTTCTGTT 
GGCAATTTTA TCAGCACAAA GAGCATCCAG AGTGACGAGC GGGATGACAT CACAGAGAAC 
TACAAGTATG AAGAAGGATC CCTCCAGGAG AGGCAGGTGT TTCTGAAGGC TCTGCAGAAG 
CTGAAGGCTA GAAGCTTCCA TGGCTCCCAA AGAGGAGCAG AGTTGCAACC TTCCAGGCCC 
ACATCACTGA GCCAGGACAG CCCTCGGAGC CTGCATACAC CTTCCCTTCG ACCCAGTGAT 
GTGGTGCAAG TCTCCCTGAA ATTCAAGCTG CTCGACCCGC CCAACATGGG CCAGGATATA 
TGCTTTGTCC TGCTGGCCCT CAACATGTCC TCCCAGTTCA AGGACCTCAA AGTGAACCTG 
AGTGCCCAGT CTCTGCTGCA CGATGGCAGC CCCCTGTCCC CATTCTGGCA GGACACAGCG 
TTCATCACAC TCTCTCCTAA AGAAGCAAAG ACCTACCCCT GCAAAATCTC CTATTCCCAG 
TACAGCCAGT ACCTGTCAAC AGACAAGCTG ATCCGCATCA GTGCCCTGGG TGAAGAGAAA 
AGCAGTCCTG AGAAAATCCT GGTGAACAAG ATCATCACCT TATCTTATCC AAGCATCACG 
ATTAATGTTC TAGGAGCAGC CGTTGTGAAC CAGCCACTCT CCATACAGGT GATATTTTCA 
AACCCCCTCT CGGAGCAGGT TGAGGACTGT GTGCTGACTG TGGAAGGAAG TGGCCTCTTC 
AAGAAACAGC AGAAAGTCTT CCTTGGAGTC CTCAAACCCC AACACCAAGC AAGCATCATT 
CTGGAGACCG TCCCCTTCAA GAGTGGACAA AGGCAGATCC AAGCTAATAT GAGAAGCAAC 
AAGTTTAAGG ACATTAAGGG TTACAGGAAT GTTTATGTAG ACTTTGCATT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016878218.1
CDS	244..1377
Translation	MARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL

Target ORF information:

RefSeq Version	XM_017022729.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 5 (TGM5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022729.1

ORF Insert Sequence:

ATGGCCCGGA AGGATCTGCC CCCTGCATAT GGAGGCTGGC AGGTGCTGGA CGCCACACCT 
CAGGAGATGA GCAACGGCGT CTACTGCTGT GGCCCTGCCT CTGTCAGAGC CATCAAAGAA 
GGAGAAGTGG ACCTGAACTA TGACACGCCC TTTGTGTTTT CGATGGTGAA TGCTGACTGC 
ATGTCCTGGC TCGTCCAGGG AGGGAAGGAG CAGAAGCTTC ACCAGGACAC GAGTTCTGTT 
GGCAATTTTA TCAGCACAAA GAGCATCCAG AGTGACGAGC GGGATGACAT CACAGAGAAC 
TACAAGTATG AAGAAGGATC CCTCCAGGAG AGGCAGGTGT TTCTGAAGGC TCTGCAGAAG 
CTGAAGGCTA GAAGCTTCCA TGGCTCCCAA AGAGGAGCAG AGTTGCAACC TTCCAGGCCC 
ACATCACTGA GCCAGGACAG CCCTCGGAGC CTGCATACAC CTTCCCTTCG ACCCAGTGAT 
GTGGTGCAAG TCTCCCTGAA ATTCAAGCTG CTCGACCCGC CCAACATGGG CCAGGATATA 
TGCTTTGTCC TGCTGGCCCT CAACATGTCC TCCCAGTTCA AGGACCTCAA AGTGAACCTG 
AGTGCCCAGT CTCTGCTGCA CGATGGCAGC CCCCTGTCCC CATTCTGGCA GGACACAGCG 
TTCATCACAC TCTCTCCTAA AGAAGCAAAG ACCTACCCCT GCAAAATCTC CTATTCCCAG 
TACAGCCAGT ACCTGTCAAC AGACAAGCTG ATCCGCATCA GTGCCCTGGG TGAAGAGAAA 
AGCAGTCCTG AGAAAATCCT GGTGAACAAG ATCATCACCT TATCTTATCC AAGCATCACG 
ATTAATGTTC TAGGAGCAGC CGTTGTGAAC CAGCCACTCT CCATACAGGT GATATTTTCA 
AACCCCCTCT CGGAGCAGGT TGAGGACTGT GTGCTGACTG TGGAAGGAAG TGGCCTCTTC 
AAGAAACAGC AGAAAGTCTT CCTTGGAGTC CTCAAACCCC AACACCAAGC AAGCATCATT 
CTGGAGACCG TCCCCTTCAA GAGTGGACAA AGGCAGATCC AAGCTAATAT GAGAAGCAAC 
AAGTTTAAGG ACATTAAGGG TTACAGGAAT GTTTATGTAG ACTTTGCATT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TGM5 ( XM_011522230.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011520532.1 Homo sapiens transglutaminase 5 (TGM5), transcript variant X1, mRNA.

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CloneID	OHu62701
Clone ID Related Accession (Same CDS sequence)	XM_017022729.1 , XM_011522230.2
Accession Version	XM_011522230.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011522230.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCGGA AGGATCTGCC CCCTGCATAT GGAGGCTGGC AGGTGCTGGA CGCCACACCT 
CAGGAGATGA GCAACGGCGT CTACTGCTGT GGCCCTGCCT CTGTCAGAGC CATCAAAGAA 
GGAGAAGTGG ACCTGAACTA TGACACGCCC TTTGTGTTTT CGATGGTGAA TGCTGACTGC 
ATGTCCTGGC TCGTCCAGGG AGGGAAGGAG CAGAAGCTTC ACCAGGACAC GAGTTCTGTT 
GGCAATTTTA TCAGCACAAA GAGCATCCAG AGTGACGAGC GGGATGACAT CACAGAGAAC 
TACAAGTATG AAGAAGGATC CCTCCAGGAG AGGCAGGTGT TTCTGAAGGC TCTGCAGAAG 
CTGAAGGCTA GAAGCTTCCA TGGCTCCCAA AGAGGAGCAG AGTTGCAACC TTCCAGGCCC 
ACATCACTGA GCCAGGACAG CCCTCGGAGC CTGCATACAC CTTCCCTTCG ACCCAGTGAT 
GTGGTGCAAG TCTCCCTGAA ATTCAAGCTG CTCGACCCGC CCAACATGGG CCAGGATATA 
TGCTTTGTCC TGCTGGCCCT CAACATGTCC TCCCAGTTCA AGGACCTCAA AGTGAACCTG 
AGTGCCCAGT CTCTGCTGCA CGATGGCAGC CCCCTGTCCC CATTCTGGCA GGACACAGCG 
TTCATCACAC TCTCTCCTAA AGAAGCAAAG ACCTACCCCT GCAAAATCTC CTATTCCCAG 
TACAGCCAGT ACCTGTCAAC AGACAAGCTG ATCCGCATCA GTGCCCTGGG TGAAGAGAAA 
AGCAGTCCTG AGAAAATCCT GGTGAACAAG ATCATCACCT TATCTTATCC AAGCATCACG 
ATTAATGTTC TAGGAGCAGC CGTTGTGAAC CAGCCACTCT CCATACAGGT GATATTTTCA 
AACCCCCTCT CGGAGCAGGT TGAGGACTGT GTGCTGACTG TGGAAGGAAG TGGCCTCTTC 
AAGAAACAGC AGAAAGTCTT CCTTGGAGTC CTCAAACCCC AACACCAAGC AAGCATCATT 
CTGGAGACCG TCCCCTTCAA GAGTGGACAA AGGCAGATCC AAGCTAATAT GAGAAGCAAC 
AAGTTTAAGG ACATTAAGGG TTACAGGAAT GTTTATGTAG ACTTTGCATT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011520532.1
CDS	220..1353
Translation	MARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL

Target ORF information:

RefSeq Version	XM_011522230.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 5 (TGM5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011522230.2

ORF Insert Sequence:

ATGGCCCGGA AGGATCTGCC CCCTGCATAT GGAGGCTGGC AGGTGCTGGA CGCCACACCT 
CAGGAGATGA GCAACGGCGT CTACTGCTGT GGCCCTGCCT CTGTCAGAGC CATCAAAGAA 
GGAGAAGTGG ACCTGAACTA TGACACGCCC TTTGTGTTTT CGATGGTGAA TGCTGACTGC 
ATGTCCTGGC TCGTCCAGGG AGGGAAGGAG CAGAAGCTTC ACCAGGACAC GAGTTCTGTT 
GGCAATTTTA TCAGCACAAA GAGCATCCAG AGTGACGAGC GGGATGACAT CACAGAGAAC 
TACAAGTATG AAGAAGGATC CCTCCAGGAG AGGCAGGTGT TTCTGAAGGC TCTGCAGAAG 
CTGAAGGCTA GAAGCTTCCA TGGCTCCCAA AGAGGAGCAG AGTTGCAACC TTCCAGGCCC 
ACATCACTGA GCCAGGACAG CCCTCGGAGC CTGCATACAC CTTCCCTTCG ACCCAGTGAT 
GTGGTGCAAG TCTCCCTGAA ATTCAAGCTG CTCGACCCGC CCAACATGGG CCAGGATATA 
TGCTTTGTCC TGCTGGCCCT CAACATGTCC TCCCAGTTCA AGGACCTCAA AGTGAACCTG 
AGTGCCCAGT CTCTGCTGCA CGATGGCAGC CCCCTGTCCC CATTCTGGCA GGACACAGCG 
TTCATCACAC TCTCTCCTAA AGAAGCAAAG ACCTACCCCT GCAAAATCTC CTATTCCCAG 
TACAGCCAGT ACCTGTCAAC AGACAAGCTG ATCCGCATCA GTGCCCTGGG TGAAGAGAAA 
AGCAGTCCTG AGAAAATCCT GGTGAACAAG ATCATCACCT TATCTTATCC AAGCATCACG 
ATTAATGTTC TAGGAGCAGC CGTTGTGAAC CAGCCACTCT CCATACAGGT GATATTTTCA 
AACCCCCTCT CGGAGCAGGT TGAGGACTGT GTGCTGACTG TGGAAGGAAG TGGCCTCTTC 
AAGAAACAGC AGAAAGTCTT CCTTGGAGTC CTCAAACCCC AACACCAAGC AAGCATCATT 
CTGGAGACCG TCCCCTTCAA GAGTGGACAA AGGCAGATCC AAGCTAATAT GAGAAGCAAC 
AAGTTTAAGG ACATTAAGGG TTACAGGAAT GTTTATGTAG ACTTTGCATT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TGM5 ( NM_004245.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004236.1 Homo sapiens transglutaminase 5 (TGM5), transcript variant 2, mRNA.

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CloneID	OHu01390
Clone ID Related Accession (Same CDS sequence)	NM_004245.3 , NM_004245.4
Accession Version	NM_004245.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC119009.1, AK298479.1, AC068724.7, AW467571.1 and CA314704.1. On Nov 4, 2009 this sequence version replaced NM_004245.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2, also referred to as the short form), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF035961.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAAG GGCTAGAAGT GGCCCTCACA GACCTCCAGA GCTCCAGAAA TAATGTGCGG 
CACCACACGG AGGAGATCAC TGTGGACCAC CTGCTTGTTC GCCGGGGCCA GGCCTTCAAC 
CTCACCCTGT ACTTCAGGAA CCGGAGCTTC CAGCCAGGCC TGGACAACAT CATCTTCGTG 
GTTGAAACTG AGGATGCTGT CTACTTGGAC AGTGAACCCC AGAGGCAGGA GTATGTCATG 
AATGATTATG GCTTCATCTA CCAAGGCAGC AAGAACTGGA TCCGCCCATG TCCCTGGAAC 
TATGGACAGT TTGAAGACAA AATCATAGAC ATCTGCCTGA AGCTGCTAGA CAAGAGCCTG 
CACTTCCAGA CTGACCCAGC CACAGACTGT GCTCTGCGGG GAAGCCCCGT CTACGTCAGC 
AGAGTGGTGT GTGCCATGAT CAACAGCAAT GATGATAATG GGGTGCTCAA TGGAAACTGG 
AGTGAGAATT ACACAGACGG CGCCAACCCT GCGGAGTGGA CGGGCAGCGT GGCCATCCTG 
AAGCAGTGGA ACGCCACAGG CTGCCAGCCC GTGCGCTACG GGCAATGCTG GGTCTTTGCT 
GCCGTCATGT GCACAGTGAT GAGGTGTCTG GGGATCCCTA CCCGTGTGAT CACCAACTTC 
GACTCTGGCC ACGATACAGA TGGAAACCTG ATCATAGATG AGTATTATGA CAACACAGGC 
AGGATTTTGG GGAATAAGAA GAAGGATACT ATCTGGAACT TCCATGTCTG GAATGAGTGC 
TGGATGGCCC GGAAGGATCT GCCCCCTGCA TATGGAGGCT GGCAGGTGCT GGACGCCACA 
CCTCAGGAGA TGAGCAACGG CGTCTACTGC TGTGGCCCTG CCTCTGTCAG AGCCATCAAA 
GAAGGAGAAG TGGACCTGAA CTATGACACG CCCTTTGTGT TTTCGATGGT GAATGCTGAC 
TGCATGTCCT GGCTCGTCCA GGGAGGGAAG GAGCAGAAGC TTCACCAGGA CACGAGTTCT 
GTTGGCAATT TTATCAGCAC AAAGAGCATC CAGAGTGACG AGCGGGATGA CATCACAGAG 
AACTACAAGT ATGAAGAAGG ATCCCTCCAG GAGAGGCAGG TGTTTCTGAA GGCTCTGCAG 
AAGCTGAAGG CTAGAAGCTT CCATGGCTCC CAAAGAGGAG CAGAGTTGCA ACCTTCCAGG 
CCCACATCAC TGAGCCAGGA CAGCCCTCGG AGCCTGCATA CACCTTCCCT TCGACCCAGT 
GATGTGGTGC AAGTCTCCCT GAAATTCAAG CTGCTCGACC CGCCCAACAT GGGCCAGGAT 
ATATGCTTTG TCCTGCTGGC CCTCAACATG TCCTCCCAGT TCAAGGACCT CAAAGTGAAC 
CTGAGTGCCC AGTCTCTGCT GCACGATGGC AGCCCCCTGT CCCCATTCTG GCAGGACACA 
GCGTTCATCA CACTCTCTCC TAAAGAAGCA AAGACCTACC CCTGCAAAAT CTCCTATTCC 
CAGTACAGCC AGTACCTGTC AACAGACAAG CTGATCCGCA TCAGTGCCCT GGGTGAAGAG 
AAAAGCAGTC CTGAGAAAAT CCTGGTGAAC AAGATCATCA CCTTATCTTA TCCAAGCATC 
ACGATTAATG TTCTAGGAGC AGCCGTTGTG AACCAGCCAC TCTCCATACA GGTGATATTT 
TCAAACCCCC TCTCGGAGCA GGTTGAGGAC TGTGTGCTGA CTGTGGAAGG AAGTGGCCTC 
TTCAAGAAAC AGCAGAAAGT CTTCCTTGGA GTCCTCAAAC CCCAACACCA AGCAAGCATC 
ATTCTGGAGA CCGTCCCCTT CAAGAGTGGA CAAAGGCAGA TCCAAGCTAA TATGAGAAGC 
AACAAGTTTA AGGACATTAA GGGTTACAGG AATGTTTATG TAGACTTTGC ATTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004236.1
CDS	9..1925
Translation	MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVETEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL

Target ORF information:

RefSeq Version	NM_004245.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 5 (TGM5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004245.3

ORF Insert Sequence:

ATGGCCCAAG GGCTAGAAGT GGCCCTCACA GACCTCCAGA GCTCCAGAAA TAATGTGCGG 
CACCACACGG AGGAGATCAC TGTGGACCAC CTGCTTGTTC GCCGGGGCCA GGCCTTCAAC 
CTCACCCTGT ACTTCAGGAA CCGGAGCTTC CAGCCAGGCC TGGACAACAT CATCTTCGTG 
GTTGAAACTG AGGATGCTGT CTACTTGGAC AGTGAACCCC AGAGGCAGGA GTATGTCATG 
AATGATTATG GCTTCATCTA CCAAGGCAGC AAGAACTGGA TCCGCCCATG TCCCTGGAAC 
TATGGACAGT TTGAAGACAA AATCATAGAC ATCTGCCTGA AGCTGCTAGA CAAGAGCCTG 
CACTTCCAGA CTGACCCAGC CACAGACTGT GCTCTGCGGG GAAGCCCCGT CTACGTCAGC 
AGAGTGGTGT GTGCCATGAT CAACAGCAAT GATGATAATG GGGTGCTCAA TGGAAACTGG 
AGTGAGAATT ACACAGACGG CGCCAACCCT GCGGAGTGGA CGGGCAGCGT GGCCATCCTG 
AAGCAGTGGA ACGCCACAGG CTGCCAGCCC GTGCGCTACG GGCAATGCTG GGTCTTTGCT 
GCCGTCATGT GCACAGTGAT GAGGTGTCTG GGGATCCCTA CCCGTGTGAT CACCAACTTC 
GACTCTGGCC ACGATACAGA TGGAAACCTG ATCATAGATG AGTATTATGA CAACACAGGC 
AGGATTTTGG GGAATAAGAA GAAGGATACT ATCTGGAACT TCCATGTCTG GAATGAGTGC 
TGGATGGCCC GGAAGGATCT GCCCCCTGCA TATGGAGGCT GGCAGGTGCT GGACGCCACA 
CCTCAGGAGA TGAGCAACGG CGTCTACTGC TGTGGCCCTG CCTCTGTCAG AGCCATCAAA 
GAAGGAGAAG TGGACCTGAA CTATGACACG CCCTTTGTGT TTTCGATGGT GAATGCTGAC 
TGCATGTCCT GGCTCGTCCA GGGAGGGAAG GAGCAGAAGC TTCACCAGGA CACGAGTTCT 
GTTGGCAATT TTATCAGCAC AAAGAGCATC CAGAGTGACG AGCGGGATGA CATCACAGAG 
AACTACAAGT ATGAAGAAGG ATCCCTCCAG GAGAGGCAGG TGTTTCTGAA GGCTCTGCAG 
AAGCTGAAGG CTAGAAGCTT CCATGGCTCC CAAAGAGGAG CAGAGTTGCA ACCTTCCAGG 
CCCACATCAC TGAGCCAGGA CAGCCCTCGG AGCCTGCATA CACCTTCCCT TCGACCCAGT 
GATGTGGTGC AAGTCTCCCT GAAATTCAAG CTGCTCGACC CGCCCAACAT GGGCCAGGAT 
ATATGCTTTG TCCTGCTGGC CCTCAACATG TCCTCCCAGT TCAAGGACCT CAAAGTGAAC 
CTGAGTGCCC AGTCTCTGCT GCACGATGGC AGCCCCCTGT CCCCATTCTG GCAGGACACA 
GCGTTCATCA CACTCTCTCC TAAAGAAGCA AAGACCTACC CCTGCAAAAT CTCCTATTCC 
CAGTACAGCC AGTACCTGTC AACAGACAAG CTGATCCGCA TCAGTGCCCT GGGTGAAGAG 
AAAAGCAGTC CTGAGAAAAT CCTGGTGAAC AAGATCATCA CCTTATCTTA TCCAAGCATC 
ACGATTAATG TTCTAGGAGC AGCCGTTGTG AACCAGCCAC TCTCCATACA GGTGATATTT 
TCAAACCCCC TCTCGGAGCA GGTTGAGGAC TGTGTGCTGA CTGTGGAAGG AAGTGGCCTC 
TTCAAGAAAC AGCAGAAAGT CTTCCTTGGA GTCCTCAAAC CCCAACACCA AGCAAGCATC 
ATTCTGGAGA CCGTCCCCTT CAAGAGTGGA CAAAGGCAGA TCCAAGCTAA TATGAGAAGC 
AACAAGTTTA AGGACATTAA GGGTTACAGG AATGTTTATG TAGACTTTGC ATTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TGM5 ( NM_004245.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004236.1 Homo sapiens transglutaminase 5 (TGM5), transcript variant 2, mRNA.

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CloneID	OHu01390
Clone ID Related Accession (Same CDS sequence)	NM_004245.3 , NM_004245.4
Accession Version	NM_004245.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-14
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009852.9, BC119009.1, AK298479.1, AC068724.7, AW467571.1 and CA314704.1. On May 31, 2019 this sequence version replaced NM_004245.3. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2, also referred to as the short form), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF035961.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAAG GGCTAGAAGT GGCCCTCACA GACCTCCAGA GCTCCAGAAA TAATGTGCGG 
CACCACACGG AGGAGATCAC TGTGGACCAC CTGCTTGTTC GCCGGGGCCA GGCCTTCAAC 
CTCACCCTGT ACTTCAGGAA CCGGAGCTTC CAGCCAGGCC TGGACAACAT CATCTTCGTG 
GTTGAAACTG AGGATGCTGT CTACTTGGAC AGTGAACCCC AGAGGCAGGA GTATGTCATG 
AATGATTATG GCTTCATCTA CCAAGGCAGC AAGAACTGGA TCCGCCCATG TCCCTGGAAC 
TATGGACAGT TTGAAGACAA AATCATAGAC ATCTGCCTGA AGCTGCTAGA CAAGAGCCTG 
CACTTCCAGA CTGACCCAGC CACAGACTGT GCTCTGCGGG GAAGCCCCGT CTACGTCAGC 
AGAGTGGTGT GTGCCATGAT CAACAGCAAT GATGATAATG GGGTGCTCAA TGGAAACTGG 
AGTGAGAATT ACACAGACGG CGCCAACCCT GCGGAGTGGA CGGGCAGCGT GGCCATCCTG 
AAGCAGTGGA ACGCCACAGG CTGCCAGCCC GTGCGCTACG GGCAATGCTG GGTCTTTGCT 
GCCGTCATGT GCACAGTGAT GAGGTGTCTG GGGATCCCTA CCCGTGTGAT CACCAACTTC 
GACTCTGGCC ACGATACAGA TGGAAACCTG ATCATAGATG AGTATTATGA CAACACAGGC 
AGGATTTTGG GGAATAAGAA GAAGGATACT ATCTGGAACT TCCATGTCTG GAATGAGTGC 
TGGATGGCCC GGAAGGATCT GCCCCCTGCA TATGGAGGCT GGCAGGTGCT GGACGCCACA 
CCTCAGGAGA TGAGCAACGG CGTCTACTGC TGTGGCCCTG CCTCTGTCAG AGCCATCAAA 
GAAGGAGAAG TGGACCTGAA CTATGACACG CCCTTTGTGT TTTCGATGGT GAATGCTGAC 
TGCATGTCCT GGCTCGTCCA GGGAGGGAAG GAGCAGAAGC TTCACCAGGA CACGAGTTCT 
GTTGGCAATT TTATCAGCAC AAAGAGCATC CAGAGTGACG AGCGGGATGA CATCACAGAG 
AACTACAAGT ATGAAGAAGG ATCCCTCCAG GAGAGGCAGG TGTTTCTGAA GGCTCTGCAG 
AAGCTGAAGG CTAGAAGCTT CCATGGCTCC CAAAGAGGAG CAGAGTTGCA ACCTTCCAGG 
CCCACATCAC TGAGCCAGGA CAGCCCTCGG AGCCTGCATA CACCTTCCCT TCGACCCAGT 
GATGTGGTGC AAGTCTCCCT GAAATTCAAG CTGCTCGACC CGCCCAACAT GGGCCAGGAT 
ATATGCTTTG TCCTGCTGGC CCTCAACATG TCCTCCCAGT TCAAGGACCT CAAAGTGAAC 
CTGAGTGCCC AGTCTCTGCT GCACGATGGC AGCCCCCTGT CCCCATTCTG GCAGGACACA 
GCGTTCATCA CACTCTCTCC TAAAGAAGCA AAGACCTACC CCTGCAAAAT CTCCTATTCC 
CAGTACAGCC AGTACCTGTC AACAGACAAG CTGATCCGCA TCAGTGCCCT GGGTGAAGAG 
AAAAGCAGTC CTGAGAAAAT CCTGGTGAAC AAGATCATCA CCTTATCTTA TCCAAGCATC 
ACGATTAATG TTCTAGGAGC AGCCGTTGTG AACCAGCCAC TCTCCATACA GGTGATATTT 
TCAAACCCCC TCTCGGAGCA GGTTGAGGAC TGTGTGCTGA CTGTGGAAGG AAGTGGCCTC 
TTCAAGAAAC AGCAGAAAGT CTTCCTTGGA GTCCTCAAAC CCCAACACCA AGCAAGCATC 
ATTCTGGAGA CCGTCCCCTT CAAGAGTGGA CAAAGGCAGA TCCAAGCTAA TATGAGAAGC 
AACAAGTTTA AGGACATTAA GGGTTACAGG AATGTTTATG TAGACTTTGC ATTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004236.1
CDS	80..1996
Translation	MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVETEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL

Target ORF information:

RefSeq Version	NM_004245.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 5 (TGM5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004245.4

ORF Insert Sequence:

ATGGCCCAAG GGCTAGAAGT GGCCCTCACA GACCTCCAGA GCTCCAGAAA TAATGTGCGG 
CACCACACGG AGGAGATCAC TGTGGACCAC CTGCTTGTTC GCCGGGGCCA GGCCTTCAAC 
CTCACCCTGT ACTTCAGGAA CCGGAGCTTC CAGCCAGGCC TGGACAACAT CATCTTCGTG 
GTTGAAACTG AGGATGCTGT CTACTTGGAC AGTGAACCCC AGAGGCAGGA GTATGTCATG 
AATGATTATG GCTTCATCTA CCAAGGCAGC AAGAACTGGA TCCGCCCATG TCCCTGGAAC 
TATGGACAGT TTGAAGACAA AATCATAGAC ATCTGCCTGA AGCTGCTAGA CAAGAGCCTG 
CACTTCCAGA CTGACCCAGC CACAGACTGT GCTCTGCGGG GAAGCCCCGT CTACGTCAGC 
AGAGTGGTGT GTGCCATGAT CAACAGCAAT GATGATAATG GGGTGCTCAA TGGAAACTGG 
AGTGAGAATT ACACAGACGG CGCCAACCCT GCGGAGTGGA CGGGCAGCGT GGCCATCCTG 
AAGCAGTGGA ACGCCACAGG CTGCCAGCCC GTGCGCTACG GGCAATGCTG GGTCTTTGCT 
GCCGTCATGT GCACAGTGAT GAGGTGTCTG GGGATCCCTA CCCGTGTGAT CACCAACTTC 
GACTCTGGCC ACGATACAGA TGGAAACCTG ATCATAGATG AGTATTATGA CAACACAGGC 
AGGATTTTGG GGAATAAGAA GAAGGATACT ATCTGGAACT TCCATGTCTG GAATGAGTGC 
TGGATGGCCC GGAAGGATCT GCCCCCTGCA TATGGAGGCT GGCAGGTGCT GGACGCCACA 
CCTCAGGAGA TGAGCAACGG CGTCTACTGC TGTGGCCCTG CCTCTGTCAG AGCCATCAAA 
GAAGGAGAAG TGGACCTGAA CTATGACACG CCCTTTGTGT TTTCGATGGT GAATGCTGAC 
TGCATGTCCT GGCTCGTCCA GGGAGGGAAG GAGCAGAAGC TTCACCAGGA CACGAGTTCT 
GTTGGCAATT TTATCAGCAC AAAGAGCATC CAGAGTGACG AGCGGGATGA CATCACAGAG 
AACTACAAGT ATGAAGAAGG ATCCCTCCAG GAGAGGCAGG TGTTTCTGAA GGCTCTGCAG 
AAGCTGAAGG CTAGAAGCTT CCATGGCTCC CAAAGAGGAG CAGAGTTGCA ACCTTCCAGG 
CCCACATCAC TGAGCCAGGA CAGCCCTCGG AGCCTGCATA CACCTTCCCT TCGACCCAGT 
GATGTGGTGC AAGTCTCCCT GAAATTCAAG CTGCTCGACC CGCCCAACAT GGGCCAGGAT 
ATATGCTTTG TCCTGCTGGC CCTCAACATG TCCTCCCAGT TCAAGGACCT CAAAGTGAAC 
CTGAGTGCCC AGTCTCTGCT GCACGATGGC AGCCCCCTGT CCCCATTCTG GCAGGACACA 
GCGTTCATCA CACTCTCTCC TAAAGAAGCA AAGACCTACC CCTGCAAAAT CTCCTATTCC 
CAGTACAGCC AGTACCTGTC AACAGACAAG CTGATCCGCA TCAGTGCCCT GGGTGAAGAG 
AAAAGCAGTC CTGAGAAAAT CCTGGTGAAC AAGATCATCA CCTTATCTTA TCCAAGCATC 
ACGATTAATG TTCTAGGAGC AGCCGTTGTG AACCAGCCAC TCTCCATACA GGTGATATTT 
TCAAACCCCC TCTCGGAGCA GGTTGAGGAC TGTGTGCTGA CTGTGGAAGG AAGTGGCCTC 
TTCAAGAAAC AGCAGAAAGT CTTCCTTGGA GTCCTCAAAC CCCAACACCA AGCAAGCATC 
ATTCTGGAGA CCGTCCCCTT CAAGAGTGGA CAAAGGCAGA TCCAAGCTAA TATGAGAAGC 
AACAAGTTTA AGGACATTAA GGGTTACAGG AATGTTTATG TAGACTTTGC ATTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Acral peeling skin syndrome resulting from mutations in TGM5.
Journal of the European Academy of Dermatology and Venereology : JEADV30(3)477-80(2016 Mar)
Ca?ueto J,Bueno E,Rodr?guez-Diaz E,Vicente-D?az MA,?lvarez-Cuesta CC,Gonzalvo-Rodr?guez P,Gonz?lez-Sarmiento R

Novel TGM5 mutations in acral peeling skin syndrome.
Experimental dermatology24(4)285-9(2015 Apr)
van der Velden JJ,van Geel M,Nellen RG,Jonkman MF,McGrath JA,Nanda A,Sprecher E,van Steensel MA,McLean WH,Cassidy AJ

Under-recognition of acral peeling skin syndrome: 59 new cases with 15 novel mutations.
The British journal of dermatology171(5)1206-10(2014 Nov)
Szczecinska W,Nesteruk D,Wertheim-Tysarowska K,Greenblatt DT,Baty D,Browne F,Liu L,Ozoemena L,Terron-Kwiatkowski A,McGrath JA,Mellerio JE,Morton J,Wo?niak K,Kowalewski C,Has C,Moss C

A missense mutation in TGM5 causes acral peeling skin syndrome in a Tunisian family.
The Journal of investigative dermatology129(10)2512-5(2009 Oct)
Kharfi M,El Fekih N,Ammar D,Jaafoura H,Schwonbeck S,van Steensel MA,Fazaa B,Kamoun MR,Fischer J

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TGM5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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