MMP20 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MMP20
Entrez Gene ID	9313
Full Name	matrix metallopeptidase 20
Synonyms	AI2A2,MMP-20
General protein information	Preferred Names matrix metallopeptidase 20 Names matrix metalloproteinase-20 enamel metalloproteinase matrix metalloproteinase 20 (enamelysin)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q22.2
Summary	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3. [provided by RefSeq, Aug 2011].
Disorder MIM:	604629
Disorder Html:	Amelogenesis imperfecta, type IIA2, 612529 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_004771.3	NP_004762.2	matrix metalloproteinase-20 preproprotein
NM_004771.4	NP_004762.2	matrix metalloproteinase-20 preproprotein

Pathways from BioSystems

Homologies

Homo sapiens (human)	MMP20	NP_004762.2
Pan troglodytes (chimpanzee)	MMP20	XP_001153208.1
Bos taurus (cattle)	MMP20	NP_776816.1
Danio rerio (zebrafish)	LOC100329766	XP_002664668.3
	MMP20	XP_001097602.1
Canis lupus familiaris (dog)	MMP20	XP_854639.1
Rattus norvegicus (Norway rat)	Mmp20	NP_001100270.1
Mus musculus (house mouse)	Mmp20	NP_038931.1
Xenopus tropicalis (tropical clawed frog)	mmp20	XP_002934967.2

Gene Ontology
Bibliography

Related articles in PubMed

Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk.
Chang X, Zhao Y, Hou C, Glessner J, McDaniel L, Diamond MA, Thomas K, Li J, Wei Z, Liu Y, Guo Y, Mentch FD, Qiu H, Kim C, Evans P, Vaksman Z, Diskin SJ, Attiyeh EF, Sleiman P, Maris JM, Hakonarson H
Nature communications8(1)569(2017 Sep)

MMP20 rs1784418 Protects Certain Populations against Caries.
Filho AV, Calixto MS, Deeley K, Santos N, Rosenblatt A, Vieira AR
Caries research51(1)46-51(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The article data showed that MMP20 rs1784418 C>T (Matrix metalloproteinase 20) appears to protect against dental caries, but its effects are likely to be more marked in certain populations.
Title: MMP20 rs1784418 Protects Certain Populations against Caries.

DSPP-MMP20 pair may play a role in the normal turnover of cell surface proteins and/or repair of pericellular matrix proteins of the basement membranes in the metabolically active duct epithelial system of the nephrons.
Title: Matrix Metalloproteinase 20 Co-expression With Dentin Sialophosphoprotein in Human and Monkey Kidneys.

Levels of matrix metalloproteinases MMP-19 and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC).
Title: High-Level Expression and Prognostic Significance of Matrix Metalloprotease-19 and Matrix Metalloprotease-20 in Human Pancreatic Ductal Adenocarcinoma.

The growth of choroidal neovascularization in AMD would be affected by 2 genes: MMP20, a newly confirmed gene expressed in the retina, and ARMS2/HTRA1, a well-known susceptibility gene for AMD.
Title: MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration.

The expression of MMP20 was lower in calcifying cystic odontogenic tumor when compared to all tumors and cysts.
Title: Immunohistochemical expression of WNT5A and MMPs in odontogenic epithelial tumors and cysts.

The following MMP20 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MMP20 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20263	NM_004771.4 Latest version!	Homo sapiens matrix metallopeptidase 20 (MMP20), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu20263	NM_004771.3	Homo sapiens matrix metallopeptidase 20 (MMP20), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MMP20 ( NM_004771.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004762.2 Homo sapiens matrix metallopeptidase 20 (MMP20), mRNA.

Price & Availability↑

CloneID	OHu20263
Clone ID Related Accession (Same CDS sequence)	NM_004771.3 , NM_004771.4
Accession Version	NM_004771.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-20
Organism	Homo sapiens(human)
Product	matrix metalloproteinase-20 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Y12779.1 and AJ296177.1. This sequence is a reference standard in the RefSeqGene project. On Mar 11, 2004 this sequence version replaced NM_004771.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y12779.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGTGC TCCCTGCATC TGGCCTTGCT GTCTTCCTCA TCATGGCTTT GAAGTTTTCC 
ACTGCAGCCC CCTCCCTAGT TGCAGCCTCC CCCAGGACCT GGAGGAACAA CTACCGCCTC 
GCACAGGCGT ATCTTGACAA ATATTACACA AATAAAGAAG GACACCAGAT TGGTGAGATG 
GTTGCAAGAG GAAGCAATTC CATGATAAGG AAGATTAAGG AGCTACAAGC GTTCTTTGGC 
CTCCAAGTCA CCGGGAAGTT AGACCAGACC ACAATGAACG TGATCAAGAA GCCTCGCTGT 
GGAGTTCCTG ATGTGGCCAA TTATCGCCTC TTCCCTGGTG AACCCAAATG GAAAAAAAAT 
ACTTTGACAT ACAGAATATC TAAATACACA CCTTCCATGA GTTCTGTCGA GGTGGACAAA 
GCAGTGGAGA TGGCCTTGCA GGCCTGGAGT AGCGCCGTCC CTCTGAGCTT TGTCAGAATA 
AACTCAGGAG AAGCGGATAT TATGATATCT TTTGAAAATG GAGATCACGG GGATTCCTAT 
CCATTCGATG GGCCTCGGGG GACTCTAGCC CATGCATTTG CTCCTGGAGA AGGCCTGGGA 
GGAGATACAC ATTTCGACAA TGCTGAGAAG TGGACTATGG GAACGAATGG TTTTAATTTG 
TTTACCGTTG CTGCTCATGA ATTTGGCCAT GCCCTGGGCC TGGCCCATTC CACAGACCCA 
TCAGCACTGA TGTACCCAAC TTATAAGTAC AAGAATCCCT ATGGATTCCA CCTCCCCAAA 
GATGATGTGA AAGGGATCCA GGCATTATAC GGACCTCGGA AAGTATTCCT GGGGAAGCCC 
ACTCTGCCCC ATGCCCCCCA TCACAAGCCA TCCATCCCTG ACCTCTGTGA CTCCAGCTCA 
TCCTTTGACG CTGTGACAAT GCTGGGGAAG GAGCTCCTGC TCTTCAAGGA CCGGATTTTC 
TGGAGACGGC AGGTTCACTT GCGGACAGGA ATTCGGCCCA GCACTATTAC CAGCTCCTTC 
CCCCAGCTCA TGTCCAATGT GGATGCAGCT TACGAAGTGG CTGAGAGGGG CACTGCTTAC 
TTCTTCAAAG GTCCCCACTA CTGGATAACA AGAGGATTCC AAATGCAAGG TCCTCCTCGG 
ACTATTTATG ACTTTGGATT TCCAAGGCAC GTGCAGCAAA TAGATGCTGC TGTCTACCTC 
AGGGAGCCAC AGAAGACCCT TTTCTTTGTG GGAGATGAAT ACTACAGCTA CGACGAAAGG 
AAAAGGAAAA TGGAAAAAGA CTATCCAAAG AATACTGAAG AAGAATTTTC AGGAGTAAAT 
GGCCAAATCG ATGCTGCTGT AGAATTAAAT GGCTACATTT ACTTCTTTTC AGGACCAAAA 
ACATACAAGT ATGACACAGA GAAGGAAGAT GTGGTTAGTG TGGTGAAATC TAGTTCCTGG 
ATTGGTTGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004762.2
CDS	14..1465
Translation	MKVLPASGLAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC

Target ORF information:

RefSeq Version	NM_004771.3
Organism	Homo sapiens(human)
Definition	Homo sapiens matrix metallopeptidase 20 (MMP20), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004771.3

ORF Insert Sequence:

ATGAAGGTGC TCCCTGCATC TGGCCTTGCT GTCTTCCTCA TCATGGCTTT GAAGTTTTCC 
ACTGCAGCCC CCTCCCTAGT TGCAGCCTCC CCCAGGACCT GGAGGAACAA CTACCGCCTC 
GCACAGGCGT ATCTTGACAA ATATTACACA AATAAAGAAG GACACCAGAT TGGTGAGATG 
GTTGCAAGAG GAAGCAATTC CATGATAAGG AAGATTAAGG AGCTACAAGC GTTCTTTGGC 
CTCCAAGTCA CCGGGAAGTT AGACCAGACC ACAATGAACG TGATCAAGAA GCCTCGCTGT 
GGAGTTCCTG ATGTGGCCAA TTATCGCCTC TTCCCTGGTG AACCCAAATG GAAAAAAAAT 
ACTTTGACAT ACAGAATATC TAAATACACA CCTTCCATGA GTTCTGTCGA GGTGGACAAA 
GCAGTGGAGA TGGCCTTGCA GGCCTGGAGT AGCGCCGTCC CTCTGAGCTT TGTCAGAATA 
AACTCAGGAG AAGCGGATAT TATGATATCT TTTGAAAATG GAGATCACGG GGATTCCTAT 
CCATTCGATG GGCCTCGGGG GACTCTAGCC CATGCATTTG CTCCTGGAGA AGGCCTGGGA 
GGAGATACAC ATTTCGACAA TGCTGAGAAG TGGACTATGG GAACGAATGG TTTTAATTTG 
TTTACCGTTG CTGCTCATGA ATTTGGCCAT GCCCTGGGCC TGGCCCATTC CACAGACCCA 
TCAGCACTGA TGTACCCAAC TTATAAGTAC AAGAATCCCT ATGGATTCCA CCTCCCCAAA 
GATGATGTGA AAGGGATCCA GGCATTATAC GGACCTCGGA AAGTATTCCT GGGGAAGCCC 
ACTCTGCCCC ATGCCCCCCA TCACAAGCCA TCCATCCCTG ACCTCTGTGA CTCCAGCTCA 
TCCTTTGACG CTGTGACAAT GCTGGGGAAG GAGCTCCTGC TCTTCAAGGA CCGGATTTTC 
TGGAGACGGC AGGTTCACTT GCGGACAGGA ATTCGGCCCA GCACTATTAC CAGCTCCTTC 
CCCCAGCTCA TGTCCAATGT GGATGCAGCT TACGAAGTGG CTGAGAGGGG CACTGCTTAC 
TTCTTCAAAG GTCCCCACTA CTGGATAACA AGAGGATTCC AAATGCAAGG TCCTCCTCGG 
ACTATTTATG ACTTTGGATT TCCAAGGCAC GTGCAGCAAA TAGATGCTGC TGTCTACCTC 
AGGGAGCCAC AGAAGACCCT TTTCTTTGTG GGAGATGAAT ACTACAGCTA CGACGAAAGG 
AAAAGGAAAA TGGAAAAAGA CTATCCAAAG AATACTGAAG AAGAATTTTC AGGAGTAAAT 
GGCCAAATCG ATGCTGCTGT AGAATTAAAT GGCTACATTT ACTTCTTTTC AGGACCAAAA 
ACATACAAGT ATGACACAGA GAAGGAAGAT GTGGTTAGTG TGGTGAAATC TAGTTCCTGG 
ATTGGTTGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MMP20 ( NM_004771.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004762.2 Homo sapiens matrix metallopeptidase 20 (MMP20), mRNA.

Price & Availability↑

CloneID	OHu20263
Clone ID Related Accession (Same CDS sequence)	NM_004771.3 , NM_004771.4
Accession Version	NM_004771.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	matrix metalloproteinase-20 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000851.4. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_004771.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y12779.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000260228.3/ ENSP00000260228.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGGTGC TCCCTGCATC TGGCCTTGCT GTCTTCCTCA TCATGGCTTT GAAGTTTTCC 
ACTGCAGCCC CCTCCCTAGT TGCAGCCTCC CCCAGGACCT GGAGGAACAA CTACCGCCTC 
GCACAGGCGT ATCTTGACAA ATATTACACA AATAAAGAAG GACACCAGAT TGGTGAGATG 
GTTGCAAGAG GAAGCAATTC CATGATAAGG AAGATTAAGG AGCTACAAGC GTTCTTTGGC 
CTCCAAGTCA CCGGGAAGTT AGACCAGACC ACAATGAACG TGATCAAGAA GCCTCGCTGT 
GGAGTTCCTG ATGTGGCCAA TTATCGCCTC TTCCCTGGTG AACCCAAATG GAAAAAAAAT 
ACTTTGACAT ACAGAATATC TAAATACACA CCTTCCATGA GTTCTGTCGA GGTGGACAAA 
GCAGTGGAGA TGGCCTTGCA GGCCTGGAGT AGCGCCGTCC CTCTGAGCTT TGTCAGAATA 
AACTCAGGAG AAGCGGATAT TATGATATCT TTTGAAAATG GAGATCACGG GGATTCCTAT 
CCATTCGATG GGCCTCGGGG GACTCTAGCC CATGCATTTG CTCCTGGAGA AGGCCTGGGA 
GGAGATACAC ATTTCGACAA TGCTGAGAAG TGGACTATGG GAACGAATGG TTTTAATTTG 
TTTACCGTTG CTGCTCATGA ATTTGGCCAT GCCCTGGGCC TGGCCCATTC CACAGACCCA 
TCAGCACTGA TGTACCCAAC TTATAAGTAC AAGAATCCCT ATGGATTCCA CCTCCCCAAA 
GATGATGTGA AAGGGATCCA GGCATTATAC GGACCTCGGA AAGTATTCCT GGGGAAGCCC 
ACTCTGCCCC ATGCCCCCCA TCACAAGCCA TCCATCCCTG ACCTCTGTGA CTCCAGCTCA 
TCCTTTGACG CTGTGACAAT GCTGGGGAAG GAGCTCCTGC TCTTCAAGGA CCGGATTTTC 
TGGAGACGGC AGGTTCACTT GCGGACAGGA ATTCGGCCCA GCACTATTAC CAGCTCCTTC 
CCCCAGCTCA TGTCCAATGT GGATGCAGCT TACGAAGTGG CTGAGAGGGG CACTGCTTAC 
TTCTTCAAAG GTCCCCACTA CTGGATAACA AGAGGATTCC AAATGCAAGG TCCTCCTCGG 
ACTATTTATG ACTTTGGATT TCCAAGGCAC GTGCAGCAAA TAGATGCTGC TGTCTACCTC 
AGGGAGCCAC AGAAGACCCT TTTCTTTGTG GGAGATGAAT ACTACAGCTA CGACGAAAGG 
AAAAGGAAAA TGGAAAAAGA CTATCCAAAG AATACTGAAG AAGAATTTTC AGGAGTAAAT 
GGCCAAATCG ATGCTGCTGT AGAATTAAAT GGCTACATTT ACTTCTTTTC AGGACCAAAA 
ACATACAAGT ATGACACAGA GAAGGAAGAT GTGGTTAGTG TGGTGAAATC TAGTTCCTGG 
ATTGGTTGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004762.2
CDS	14..1465
Translation	MKVLPASGLAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC

Target ORF information:

RefSeq Version	NM_004771.4
Organism	Homo sapiens(human)
Definition	Homo sapiens matrix metallopeptidase 20 (MMP20), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004771.4

ORF Insert Sequence:

ATGAAGGTGC TCCCTGCATC TGGCCTTGCT GTCTTCCTCA TCATGGCTTT GAAGTTTTCC 
ACTGCAGCCC CCTCCCTAGT TGCAGCCTCC CCCAGGACCT GGAGGAACAA CTACCGCCTC 
GCACAGGCGT ATCTTGACAA ATATTACACA AATAAAGAAG GACACCAGAT TGGTGAGATG 
GTTGCAAGAG GAAGCAATTC CATGATAAGG AAGATTAAGG AGCTACAAGC GTTCTTTGGC 
CTCCAAGTCA CCGGGAAGTT AGACCAGACC ACAATGAACG TGATCAAGAA GCCTCGCTGT 
GGAGTTCCTG ATGTGGCCAA TTATCGCCTC TTCCCTGGTG AACCCAAATG GAAAAAAAAT 
ACTTTGACAT ACAGAATATC TAAATACACA CCTTCCATGA GTTCTGTCGA GGTGGACAAA 
GCAGTGGAGA TGGCCTTGCA GGCCTGGAGT AGCGCCGTCC CTCTGAGCTT TGTCAGAATA 
AACTCAGGAG AAGCGGATAT TATGATATCT TTTGAAAATG GAGATCACGG GGATTCCTAT 
CCATTCGATG GGCCTCGGGG GACTCTAGCC CATGCATTTG CTCCTGGAGA AGGCCTGGGA 
GGAGATACAC ATTTCGACAA TGCTGAGAAG TGGACTATGG GAACGAATGG TTTTAATTTG 
TTTACCGTTG CTGCTCATGA ATTTGGCCAT GCCCTGGGCC TGGCCCATTC CACAGACCCA 
TCAGCACTGA TGTACCCAAC TTATAAGTAC AAGAATCCCT ATGGATTCCA CCTCCCCAAA 
GATGATGTGA AAGGGATCCA GGCATTATAC GGACCTCGGA AAGTATTCCT GGGGAAGCCC 
ACTCTGCCCC ATGCCCCCCA TCACAAGCCA TCCATCCCTG ACCTCTGTGA CTCCAGCTCA 
TCCTTTGACG CTGTGACAAT GCTGGGGAAG GAGCTCCTGC TCTTCAAGGA CCGGATTTTC 
TGGAGACGGC AGGTTCACTT GCGGACAGGA ATTCGGCCCA GCACTATTAC CAGCTCCTTC 
CCCCAGCTCA TGTCCAATGT GGATGCAGCT TACGAAGTGG CTGAGAGGGG CACTGCTTAC 
TTCTTCAAAG GTCCCCACTA CTGGATAACA AGAGGATTCC AAATGCAAGG TCCTCCTCGG 
ACTATTTATG ACTTTGGATT TCCAAGGCAC GTGCAGCAAA TAGATGCTGC TGTCTACCTC 
AGGGAGCCAC AGAAGACCCT TTTCTTTGTG GGAGATGAAT ACTACAGCTA CGACGAAAGG 
AAAAGGAAAA TGGAAAAAGA CTATCCAAAG AATACTGAAG AAGAATTTTC AGGAGTAAAT 
GGCCAAATCG ATGCTGCTGT AGAATTAAAT GGCTACATTT ACTTCTTTTC AGGACCAAAA 
ACATACAAGT ATGACACAGA GAAGGAAGAT GTGGTTAGTG TGGTGAAATC TAGTTCCTGG 
ATTGGTTGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk.
Nature communications8(1)569(2017 Sep)
Chang X,Zhao Y,Hou C,Glessner J,McDaniel L,Diamond MA,Thomas K,Li J,Wei Z,Liu Y,Guo Y,Mentch FD,Qiu H,Kim C,Evans P,Vaksman Z,Diskin SJ,Attiyeh EF,Sleiman P,Maris JM,Hakonarson H

MMP20 rs1784418 Protects Certain Populations against Caries.
Caries research51(1)46-51(2017)
Filho AV,Calixto MS,Deeley K,Santos N,Rosenblatt A,Vieira AR

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MMP20 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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