MS4A1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MS4A1
Entrez Gene ID	931
Full Name	membrane spanning 4-domains A1
Synonyms	B1,Bp35,CD20,CVID5,LEU-16,MS4A2,S7
General protein information	Preferred Names membrane spanning 4-domains A1 Names B-lymphocyte antigen CD20 B-lymphocyte cell-surface antigen B1 CD20 antigen CD20 receptor leukocyte surface antigen Leu-16 membrane-spanning 4-domains, subfamily A, member 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q12.2
Summary	This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008].
Disorder MIM:	112210
Disorder Html:	Immunodeficiency, common variable, 5, 613495 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_152866.2	NP_690605.1	B-lymphocyte antigen CD20
NM_152867.2	NP_690606.1	B-lymphocyte antigen CD20
NM_021950.3	NP_068769.2	B-lymphocyte antigen CD20
NM_152866.3	NP_690605.1	B-lymphocyte antigen CD20

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MS4A1	XP_508461.2
Bos taurus (cattle)	MS4A1	NP_001071322.1
Canis lupus familiaris (dog)	MS4A1	NP_001041493.1
Mus musculus (house mouse)	Ms4a1	NP_031667.1
	MS4A1	XP_001086364.1
Rattus norvegicus (Norway rat)	Ms4a1	NP_001101048.1
Homo sapiens (human)	MS4A1	NP_690605.1

Gene Ontology
Bibliography

Related articles in PubMed

Aberrant expression of CD20 in thyroid cancer and its clinicopathologic significance.
Bychkov A, Jung CK
Human pathology7174-83(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Case Report: primary cutaneous T-cell lymphoma with aberrant CD20 expression.
Title: Primary Cutaneous T-cell Lymphoma with Aberrant Expression of CD20.

PZ-DHA also arrested MDA-MB-231 cell division at the G2/M phase and down-regulated expression of cyclin B1 and cyclin-dependent kinase 1 (CDK1)
Title: Docosahexaenoic acid-acylated phloridzin, a novel polyphenol fatty acid ester derivative, is cytotoxic to breast cancer cells.

Data suggest that insulitis (destruction of pancreatic beta-cells and their ability to produce/secrete insulin) occurs in two distinct profiles in type 1 diabetes; these differ in proportion of CD20-positive B-lymphocytes (relative to CD4-positive T-lymphocytes) present within the infiltrate; greater infiltration of CD20-positive B-lymphocytes leads to more aggressive disease progression.
Title: Differential Insulitic Profiles Determine the Extent of ?-Cell Destruction and the Age at Onset of Type 1 Diabetes.

Limiting the antibody-induced induction of immunosuppressive reactive oxygen species may improve the anti-leukemic efficacy of anti-CD20 therapy in chronic lymphocytic leukemia.
Title: Reactive oxygen species induced by therapeutic CD20 antibodies inhibit natural killer cell-mediated antibody-dependent cellular cytotoxicity against primary CLL cells.

Data indicate that Philadelphia chromosome-positive (Ph-positive) acute lymphoblastic leukemia (ALL) patients who presented with cyclin dependent kinase inhibitor 2A/B (CDKN2A/B) deletion showed a higher rate of CD20 antigen expression.
Title: Correlation between deletion of the CDKN2 gene and tyrosine kinase inhibitor resistance in adult Philadelphia chromosome-positive acute lymphoblastic leukemia.

The following MS4A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MS4A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00965	NM_021950.3 Latest version!	Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu00965	NM_152867.2 Latest version!	Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu00965	NM_152866.3 Latest version!	Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu00965	NM_152866.2	Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MS4A1 ( NM_152866.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_690605.1 Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00965
Clone ID Related Accession (Same CDS sequence)	NM_152866.2 , NM_152867.2 , NM_021950.3 , NM_152866.3
Accession Version	NM_152866.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	B-lymphocyte antigen CD20
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD691924.1, AW504475.1, BC002807.2 and AP001034.5. This sequence is a reference standard in the RefSeqGene project. On Jun 30, 2005 this sequence version replaced NM_152866.1. Transcript Variant: This variant (1) represents the longer transcript variant. Variants 1 and 3 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.27825.1, SRR1163658.295869.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACAACAC CCAGAAATTC AGTAAATGGG ACTTTCCCGG CAGAGCCAAT GAAAGGCCCT 
ATTGCTATGC AATCTGGTCC AAAACCACTC TTCAGGAGGA TGTCTTCACT GGTGGGCCCC 
ACGCAAAGCT TCTTCATGAG GGAATCTAAG ACTTTGGGGG CTGTCCAGAT TATGAATGGG 
CTCTTCCACA TTGCCCTGGG GGGTCTTCTG ATGATCCCAG CAGGGATCTA TGCACCCATC 
TGTGTGACTG TGTGGTACCC TCTCTGGGGA GGCATTATGT ATATTATTTC CGGATCACTC 
CTGGCAGCAA CGGAGAAAAA CTCCAGGAAG TGTTTGGTCA AAGGAAAAAT GATAATGAAT 
TCATTGAGCC TCTTTGCTGC CATTTCTGGA ATGATTCTTT CAATCATGGA CATACTTAAT 
ATTAAAATTT CCCATTTTTT AAAAATGGAG AGTCTGAATT TTATTAGAGC TCACACACCA 
TATATTAACA TATACAACTG TGAACCAGCT AATCCCTCTG AGAAAAACTC CCCATCTACC 
CAATACTGTT ACAGCATACA ATCTCTGTTC TTGGGCATTT TGTCAGTGAT GCTGATCTTT 
GCCTTCTTCC AGGAACTTGT AATAGCTGGC ATCGTTGAGA ATGAATGGAA AAGAACGTGC 
TCCAGACCCA AATCTAACAT AGTTCTCCTG TCAGCAGAAG AAAAAAAAGA ACAGACTATT 
GAAATAAAAG AAGAAGTGGT TGGGCTAACT GAAACATCTT CCCAACCAAA GAATGAAGAA 
GACATTGAAA TTATTCCAAT CCAAGAAGAG GAAGAAGAAG AAACAGAGAC GAACTTTCCA 
GAACCTCCCC AAGATCAGGA ATCCTCACCA ATAGAAAATG ACAGCTCTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690605.1
CDS	417..1310
Translation	MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP

Target ORF information:

RefSeq Version	NM_152866.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152866.2

ORF Insert Sequence:

ATGACAACAC CCAGAAATTC AGTAAATGGG ACTTTCCCGG CAGAGCCAAT GAAAGGCCCT 
ATTGCTATGC AATCTGGTCC AAAACCACTC TTCAGGAGGA TGTCTTCACT GGTGGGCCCC 
ACGCAAAGCT TCTTCATGAG GGAATCTAAG ACTTTGGGGG CTGTCCAGAT TATGAATGGG 
CTCTTCCACA TTGCCCTGGG GGGTCTTCTG ATGATCCCAG CAGGGATCTA TGCACCCATC 
TGTGTGACTG TGTGGTACCC TCTCTGGGGA GGCATTATGT ATATTATTTC CGGATCACTC 
CTGGCAGCAA CGGAGAAAAA CTCCAGGAAG TGTTTGGTCA AAGGAAAAAT GATAATGAAT 
TCATTGAGCC TCTTTGCTGC CATTTCTGGA ATGATTCTTT CAATCATGGA CATACTTAAT 
ATTAAAATTT CCCATTTTTT AAAAATGGAG AGTCTGAATT TTATTAGAGC TCACACACCA 
TATATTAACA TATACAACTG TGAACCAGCT AATCCCTCTG AGAAAAACTC CCCATCTACC 
CAATACTGTT ACAGCATACA ATCTCTGTTC TTGGGCATTT TGTCAGTGAT GCTGATCTTT 
GCCTTCTTCC AGGAACTTGT AATAGCTGGC ATCGTTGAGA ATGAATGGAA AAGAACGTGC 
TCCAGACCCA AATCTAACAT AGTTCTCCTG TCAGCAGAAG AAAAAAAAGA ACAGACTATT 
GAAATAAAAG AAGAAGTGGT TGGGCTAACT GAAACATCTT CCCAACCAAA GAATGAAGAA 
GACATTGAAA TTATTCCAAT CCAAGAAGAG GAAGAAGAAG AAACAGAGAC GAACTTTCCA 
GAACCTCCCC AAGATCAGGA ATCCTCACCA ATAGAAAATG ACAGCTCTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A1 ( NM_152867.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_690606.1 Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu00965
Clone ID Related Accession (Same CDS sequence)	NM_152866.2 , NM_152867.2 , NM_021950.3 , NM_152866.3
Accession Version	NM_152867.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	B-lymphocyte antigen CD20
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003127.2 and AP001034.5. On Sep 27, 2019 this sequence version replaced NM_152867.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK292168.1, SRR1163657.401896.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 5' end.

ATGACAACAC CCAGAAATTC AGTAAATGGG ACTTTCCCGG CAGAGCCAAT GAAAGGCCCT 
ATTGCTATGC AATCTGGTCC AAAACCACTC TTCAGGAGGA TGTCTTCACT GGTGGGCCCC 
ACGCAAAGCT TCTTCATGAG GGAATCTAAG ACTTTGGGGG CTGTCCAGAT TATGAATGGG 
CTCTTCCACA TTGCCCTGGG GGGTCTTCTG ATGATCCCAG CAGGGATCTA TGCACCCATC 
TGTGTGACTG TGTGGTACCC TCTCTGGGGA GGCATTATGT ATATTATTTC CGGATCACTC 
CTGGCAGCAA CGGAGAAAAA CTCCAGGAAG TGTTTGGTCA AAGGAAAAAT GATAATGAAT 
TCATTGAGCC TCTTTGCTGC CATTTCTGGA ATGATTCTTT CAATCATGGA CATACTTAAT 
ATTAAAATTT CCCATTTTTT AAAAATGGAG AGTCTGAATT TTATTAGAGC TCACACACCA 
TATATTAACA TATACAACTG TGAACCAGCT AATCCCTCTG AGAAAAACTC CCCATCTACC 
CAATACTGTT ACAGCATACA ATCTCTGTTC TTGGGCATTT TGTCAGTGAT GCTGATCTTT 
GCCTTCTTCC AGGAACTTGT AATAGCTGGC ATCGTTGAGA ATGAATGGAA AAGAACGTGC 
TCCAGACCCA AATCTAACAT AGTTCTCCTG TCAGCAGAAG AAAAAAAAGA ACAGACTATT 
GAAATAAAAG AAGAAGTGGT TGGGCTAACT GAAACATCTT CCCAACCAAA GAATGAAGAA 
GACATTGAAA TTATTCCAAT CCAAGAAGAG GAAGAAGAAG AAACAGAGAC GAACTTTCCA 
GAACCTCCCC AAGATCAGGA ATCCTCACCA ATAGAAAATG ACAGCTCTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690606.1
CDS	290..1183
Translation	MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP

Target ORF information:

RefSeq Version	NM_152867.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152867.2

ORF Insert Sequence:

ATGACAACAC CCAGAAATTC AGTAAATGGG ACTTTCCCGG CAGAGCCAAT GAAAGGCCCT 
ATTGCTATGC AATCTGGTCC AAAACCACTC TTCAGGAGGA TGTCTTCACT GGTGGGCCCC 
ACGCAAAGCT TCTTCATGAG GGAATCTAAG ACTTTGGGGG CTGTCCAGAT TATGAATGGG 
CTCTTCCACA TTGCCCTGGG GGGTCTTCTG ATGATCCCAG CAGGGATCTA TGCACCCATC 
TGTGTGACTG TGTGGTACCC TCTCTGGGGA GGCATTATGT ATATTATTTC CGGATCACTC 
CTGGCAGCAA CGGAGAAAAA CTCCAGGAAG TGTTTGGTCA AAGGAAAAAT GATAATGAAT 
TCATTGAGCC TCTTTGCTGC CATTTCTGGA ATGATTCTTT CAATCATGGA CATACTTAAT 
ATTAAAATTT CCCATTTTTT AAAAATGGAG AGTCTGAATT TTATTAGAGC TCACACACCA 
TATATTAACA TATACAACTG TGAACCAGCT AATCCCTCTG AGAAAAACTC CCCATCTACC 
CAATACTGTT ACAGCATACA ATCTCTGTTC TTGGGCATTT TGTCAGTGAT GCTGATCTTT 
GCCTTCTTCC AGGAACTTGT AATAGCTGGC ATCGTTGAGA ATGAATGGAA AAGAACGTGC 
TCCAGACCCA AATCTAACAT AGTTCTCCTG TCAGCAGAAG AAAAAAAAGA ACAGACTATT 
GAAATAAAAG AAGAAGTGGT TGGGCTAACT GAAACATCTT CCCAACCAAA GAATGAAGAA 
GACATTGAAA TTATTCCAAT CCAAGAAGAG GAAGAAGAAG AAACAGAGAC GAACTTTCCA 
GAACCTCCCC AAGATCAGGA ATCCTCACCA ATAGAAAATG ACAGCTCTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A1 ( NM_021950.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_068769.2 Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00965
Clone ID Related Accession (Same CDS sequence)	NM_152866.2 , NM_152867.2 , NM_021950.3 , NM_152866.3
Accession Version	NM_021950.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Homo sapiens(human)
Product	B-lymphocyte antigen CD20
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD691924.1, BC002807.2 and AP001034.5. On Jun 30, 2005 this sequence version replaced NM_021950.2. Transcript Variant: This variant (3) lacks a portion of the 5' UTR, compared to variant 1, but encodes the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.223920.1, SRR1163658.424843.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGACAACAC CCAGAAATTC AGTAAATGGG ACTTTCCCGG CAGAGCCAAT GAAAGGCCCT 
ATTGCTATGC AATCTGGTCC AAAACCACTC TTCAGGAGGA TGTCTTCACT GGTGGGCCCC 
ACGCAAAGCT TCTTCATGAG GGAATCTAAG ACTTTGGGGG CTGTCCAGAT TATGAATGGG 
CTCTTCCACA TTGCCCTGGG GGGTCTTCTG ATGATCCCAG CAGGGATCTA TGCACCCATC 
TGTGTGACTG TGTGGTACCC TCTCTGGGGA GGCATTATGT ATATTATTTC CGGATCACTC 
CTGGCAGCAA CGGAGAAAAA CTCCAGGAAG TGTTTGGTCA AAGGAAAAAT GATAATGAAT 
TCATTGAGCC TCTTTGCTGC CATTTCTGGA ATGATTCTTT CAATCATGGA CATACTTAAT 
ATTAAAATTT CCCATTTTTT AAAAATGGAG AGTCTGAATT TTATTAGAGC TCACACACCA 
TATATTAACA TATACAACTG TGAACCAGCT AATCCCTCTG AGAAAAACTC CCCATCTACC 
CAATACTGTT ACAGCATACA ATCTCTGTTC TTGGGCATTT TGTCAGTGAT GCTGATCTTT 
GCCTTCTTCC AGGAACTTGT AATAGCTGGC ATCGTTGAGA ATGAATGGAA AAGAACGTGC 
TCCAGACCCA AATCTAACAT AGTTCTCCTG TCAGCAGAAG AAAAAAAAGA ACAGACTATT 
GAAATAAAAG AAGAAGTGGT TGGGCTAACT GAAACATCTT CCCAACCAAA GAATGAAGAA 
GACATTGAAA TTATTCCAAT CCAAGAAGAG GAAGAAGAAG AAACAGAGAC GAACTTTCCA 
GAACCTCCCC AAGATCAGGA ATCCTCACCA ATAGAAAATG ACAGCTCTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068769.2
CDS	154..1047
Translation	MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP

Target ORF information:

RefSeq Version	NM_021950.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021950.3

ORF Insert Sequence:

ATGACAACAC CCAGAAATTC AGTAAATGGG ACTTTCCCGG CAGAGCCAAT GAAAGGCCCT 
ATTGCTATGC AATCTGGTCC AAAACCACTC TTCAGGAGGA TGTCTTCACT GGTGGGCCCC 
ACGCAAAGCT TCTTCATGAG GGAATCTAAG ACTTTGGGGG CTGTCCAGAT TATGAATGGG 
CTCTTCCACA TTGCCCTGGG GGGTCTTCTG ATGATCCCAG CAGGGATCTA TGCACCCATC 
TGTGTGACTG TGTGGTACCC TCTCTGGGGA GGCATTATGT ATATTATTTC CGGATCACTC 
CTGGCAGCAA CGGAGAAAAA CTCCAGGAAG TGTTTGGTCA AAGGAAAAAT GATAATGAAT 
TCATTGAGCC TCTTTGCTGC CATTTCTGGA ATGATTCTTT CAATCATGGA CATACTTAAT 
ATTAAAATTT CCCATTTTTT AAAAATGGAG AGTCTGAATT TTATTAGAGC TCACACACCA 
TATATTAACA TATACAACTG TGAACCAGCT AATCCCTCTG AGAAAAACTC CCCATCTACC 
CAATACTGTT ACAGCATACA ATCTCTGTTC TTGGGCATTT TGTCAGTGAT GCTGATCTTT 
GCCTTCTTCC AGGAACTTGT AATAGCTGGC ATCGTTGAGA ATGAATGGAA AAGAACGTGC 
TCCAGACCCA AATCTAACAT AGTTCTCCTG TCAGCAGAAG AAAAAAAAGA ACAGACTATT 
GAAATAAAAG AAGAAGTGGT TGGGCTAACT GAAACATCTT CCCAACCAAA GAATGAAGAA 
GACATTGAAA TTATTCCAAT CCAAGAAGAG GAAGAAGAAG AAACAGAGAC GAACTTTCCA 
GAACCTCCCC AAGATCAGGA ATCCTCACCA ATAGAAAATG ACAGCTCTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A1 ( NM_152866.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_690605.1 Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00965
Clone ID Related Accession (Same CDS sequence)	NM_152866.2 , NM_152867.2 , NM_021950.3 , NM_152866.3
Accession Version	NM_152866.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	B-lymphocyte antigen CD20
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD691924.1, AW504475.1, BC002807.2 and AP001034.5. On Sep 27, 2019 this sequence version replaced NM_152866.2. Transcript Variant: This variant (1) represents the longer transcript variant. Variants 1, 2 and 3 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.27825.1, SRR1163658.315584.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACAACAC CCAGAAATTC AGTAAATGGG ACTTTCCCGG CAGAGCCAAT GAAAGGCCCT 
ATTGCTATGC AATCTGGTCC AAAACCACTC TTCAGGAGGA TGTCTTCACT GGTGGGCCCC 
ACGCAAAGCT TCTTCATGAG GGAATCTAAG ACTTTGGGGG CTGTCCAGAT TATGAATGGG 
CTCTTCCACA TTGCCCTGGG GGGTCTTCTG ATGATCCCAG CAGGGATCTA TGCACCCATC 
TGTGTGACTG TGTGGTACCC TCTCTGGGGA GGCATTATGT ATATTATTTC CGGATCACTC 
CTGGCAGCAA CGGAGAAAAA CTCCAGGAAG TGTTTGGTCA AAGGAAAAAT GATAATGAAT 
TCATTGAGCC TCTTTGCTGC CATTTCTGGA ATGATTCTTT CAATCATGGA CATACTTAAT 
ATTAAAATTT CCCATTTTTT AAAAATGGAG AGTCTGAATT TTATTAGAGC TCACACACCA 
TATATTAACA TATACAACTG TGAACCAGCT AATCCCTCTG AGAAAAACTC CCCATCTACC 
CAATACTGTT ACAGCATACA ATCTCTGTTC TTGGGCATTT TGTCAGTGAT GCTGATCTTT 
GCCTTCTTCC AGGAACTTGT AATAGCTGGC ATCGTTGAGA ATGAATGGAA AAGAACGTGC 
TCCAGACCCA AATCTAACAT AGTTCTCCTG TCAGCAGAAG AAAAAAAAGA ACAGACTATT 
GAAATAAAAG AAGAAGTGGT TGGGCTAACT GAAACATCTT CCCAACCAAA GAATGAAGAA 
GACATTGAAA TTATTCCAAT CCAAGAAGAG GAAGAAGAAG AAACAGAGAC GAACTTTCCA 
GAACCTCCCC AAGATCAGGA ATCCTCACCA ATAGAAAATG ACAGCTCTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690605.1
CDS	379..1272
Translation	MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP

Target ORF information:

RefSeq Version	NM_152866.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A1 (MS4A1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152866.3

ORF Insert Sequence:

ATGACAACAC CCAGAAATTC AGTAAATGGG ACTTTCCCGG CAGAGCCAAT GAAAGGCCCT 
ATTGCTATGC AATCTGGTCC AAAACCACTC TTCAGGAGGA TGTCTTCACT GGTGGGCCCC 
ACGCAAAGCT TCTTCATGAG GGAATCTAAG ACTTTGGGGG CTGTCCAGAT TATGAATGGG 
CTCTTCCACA TTGCCCTGGG GGGTCTTCTG ATGATCCCAG CAGGGATCTA TGCACCCATC 
TGTGTGACTG TGTGGTACCC TCTCTGGGGA GGCATTATGT ATATTATTTC CGGATCACTC 
CTGGCAGCAA CGGAGAAAAA CTCCAGGAAG TGTTTGGTCA AAGGAAAAAT GATAATGAAT 
TCATTGAGCC TCTTTGCTGC CATTTCTGGA ATGATTCTTT CAATCATGGA CATACTTAAT 
ATTAAAATTT CCCATTTTTT AAAAATGGAG AGTCTGAATT TTATTAGAGC TCACACACCA 
TATATTAACA TATACAACTG TGAACCAGCT AATCCCTCTG AGAAAAACTC CCCATCTACC 
CAATACTGTT ACAGCATACA ATCTCTGTTC TTGGGCATTT TGTCAGTGAT GCTGATCTTT 
GCCTTCTTCC AGGAACTTGT AATAGCTGGC ATCGTTGAGA ATGAATGGAA AAGAACGTGC 
TCCAGACCCA AATCTAACAT AGTTCTCCTG TCAGCAGAAG AAAAAAAAGA ACAGACTATT 
GAAATAAAAG AAGAAGTGGT TGGGCTAACT GAAACATCTT CCCAACCAAA GAATGAAGAA 
GACATTGAAA TTATTCCAAT CCAAGAAGAG GAAGAAGAAG AAACAGAGAC GAACTTTCCA 
GAACCTCCCC AAGATCAGGA ATCCTCACCA ATAGAAAATG ACAGCTCTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Aberrant expression of CD20 in thyroid cancer and its clinicopathologic significance.
Human pathology7174-83(2018 Jan)
Bychkov A,Jung CK

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MS4A1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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