MRPS36 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MRPS36
Entrez Gene ID	92259
Full Name	mitochondrial ribosomal protein S36
Synonyms	DC47,MRP-S36
General protein information	Preferred Names mitochondrial ribosomal protein S36 Names 28S ribosomal protein S36, mitochondrial S36mt
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q13.2
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008].
Disorder MIM:	611996

mRNA and Protein(s)

mRNA	Protein	Name
NM_033281.5	NP_150597.1	28S ribosomal protein S36, mitochondrial
NM_033281.6	NP_150597.1	28S ribosomal protein S36, mitochondrial

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MRPS36	XP_001145508.1
Canis lupus familiaris (dog)	MRPS36	XP_535262.3
Bos taurus (cattle)	MRPS36	NP_001030515.1
Mus musculus (house mouse)	Mrps36	NP_079645.1
Rattus norvegicus (Norway rat)	Mrps36	NP_001178534.1
Danio rerio (zebrafish)	si:dkey-190g11.7	NP_001107080.1
Xenopus tropicalis (tropical clawed frog)	mrps36	NP_001015969.1
Homo sapiens (human)	MRPS36	NP_150597.1
	MRPS36	XP_001092626.2
Gallus gallus (chicken)	MRPS36	XP_001234565.2

Gene Ontology
Bibliography

Related articles in PubMed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.
Zhang Z, Gerstein M
Genomics81(5)468-80(2003 May)

The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present.
Cavdar Koc E, Burkhart W, Blackburn K, Moseley A, Spremulli LL
The Journal of biological chemistry276(22)19363-74(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following MRPS36 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MRPS36 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29993	NM_033281.6 Latest version!	Homo sapiens mitochondrial ribosomal protein S36 (MRPS36), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29993	NM_033281.5	Homo sapiens mitochondrial ribosomal protein S36 (MRPS36), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MRPS36 ( NM_033281.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_150597.1 Homo sapiens mitochondrial ribosomal protein S36 (MRPS36), mRNA.

Price & Availability↑

CloneID	OHu29993
Clone ID Related Accession (Same CDS sequence)	NM_033281.5 , NM_033281.6
Accession Version	NM_033281.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	28S ribosomal protein S36, mitochondrial
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX951861.1, BC015966.1 and AC145132.2. On Aug 6, 2005 this sequence version replaced NM_033281.4. ##Evidence-Data-START## Transcript exon combination :: ERR279824.6251.1, SRR1660807.297318.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGATGGGCA GCAAGATGGC GTCTGCTAGT AGGGTCGTTC AGGTAGTCAA ACCACACACT 
CCATTAATAA GGTTTCCTGA CAGAAGAGAC AATCCTAAAC CCAATGTATC AGAAGCTTTG 
AGATCAGCAG GGCTACCATC TCACTCTTCT GTAATTTCAC AACATTCTAA AGGAAGTAAA 
TCACCAGATT TGCTGATGTA TCAGGGTCCA CCAGACACTG CAGAAATAAT AAAAACATTA 
CCTCAGAAAT ACAGAAGGAA ACTTGTGTCT CAAGAAGAAA TGGAATTTAT CCAACGTGGA 
GGTCCTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150597.1
CDS	85..396
Translation	MMGSKMASASRVVQVVKPHTPLIRFPDRRDNPKPNVSEALRSAGLPSHSSVISQHSKGSKSPDLLMYQGPPDTAEIIKTLPQKYRRKLVSQEEMEFIQRGGPE

Target ORF information:

RefSeq Version	NM_033281.5
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein S36 (MRPS36), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033281.5

ORF Insert Sequence:

ATGATGGGCA GCAAGATGGC GTCTGCTAGT AGGGTCGTTC AGGTAGTCAA ACCACACACT 
CCATTAATAA GGTTTCCTGA CAGAAGAGAC AATCCTAAAC CCAATGTATC AGAAGCTTTG 
AGATCAGCAG GGCTACCATC TCACTCTTCT GTAATTTCAC AACATTCTAA AGGAAGTAAA 
TCACCAGATT TGCTGATGTA TCAGGGTCCA CCAGACACTG CAGAAATAAT AAAAACATTA 
CCTCAGAAAT ACAGAAGGAA ACTTGTGTCT CAAGAAGAAA TGGAATTTAT CCAACGTGGA 
GGTCCTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MRPS36 ( NM_033281.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_150597.1 Homo sapiens mitochondrial ribosomal protein S36 (MRPS36), mRNA.

Price & Availability↑

CloneID	OHu29993
Clone ID Related Accession (Same CDS sequence)	NM_033281.5 , NM_033281.6
Accession Version	NM_033281.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	28S ribosomal protein S36, mitochondrial
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC015966.1 and AC145132.2. On Nov 22, 2018 this sequence version replaced NM_033281.5. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.195098.1, SRR1660807.297318.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000256441.5/ ENSP00000256441.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGGGCA GCAAGATGGC GTCTGCTAGT AGGGTCGTTC AGGTAGTCAA ACCACACACT 
CCATTAATAA GGTTTCCTGA CAGAAGAGAC AATCCTAAAC CCAATGTATC AGAAGCTTTG 
AGATCAGCAG GGCTACCATC TCACTCTTCT GTAATTTCAC AACATTCTAA AGGAAGTAAA 
TCACCAGATT TGCTGATGTA TCAGGGTCCA CCAGACACTG CAGAAATAAT AAAAACATTA 
CCTCAGAAAT ACAGAAGGAA ACTTGTGTCT CAAGAAGAAA TGGAATTTAT CCAACGTGGA 
GGTCCTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150597.1
CDS	71..382
Translation	MMGSKMASASRVVQVVKPHTPLIRFPDRRDNPKPNVSEALRSAGLPSHSSVISQHSKGSKSPDLLMYQGPPDTAEIIKTLPQKYRRKLVSQEEMEFIQRGGPE

Target ORF information:

RefSeq Version	NM_033281.6
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein S36 (MRPS36), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033281.6

ORF Insert Sequence:

ATGATGGGCA GCAAGATGGC GTCTGCTAGT AGGGTCGTTC AGGTAGTCAA ACCACACACT 
CCATTAATAA GGTTTCCTGA CAGAAGAGAC AATCCTAAAC CCAATGTATC AGAAGCTTTG 
AGATCAGCAG GGCTACCATC TCACTCTTCT GTAATTTCAC AACATTCTAA AGGAAGTAAA 
TCACCAGATT TGCTGATGTA TCAGGGTCCA CCAGACACTG CAGAAATAAT AAAAACATTA 
CCTCAGAAAT ACAGAAGGAA ACTTGTGTCT CAAGAAGAAA TGGAATTTAT CCAACGTGGA 
GGTCCTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.
Genomics81(5)468-80(2003 May)
Zhang Z,Gerstein M

The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present.
The Journal of biological chemistry276(22)19363-74(2001 Jun)
Cavdar Koc E,Burkhart W,Blackburn K,Moseley A,Spremulli LL

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MRPS36 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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