TIMD4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TIMD4
Entrez Gene ID	91937
Full Name	T cell immunoglobulin and mucin domain containing 4
Synonyms	SMUCKLER,TIM4
General protein information	Preferred Names T cell immunoglobulin and mucin domain containing 4 Names T-cell immunoglobulin and mucin domain-containing protein 4 T-cell immunoglobulin mucin receptor 4 T-cell membrane protein 4 TIM-4 TIMD-4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q33.3
Disorder MIM:	610096

mRNA and Protein(s)

mRNA	Protein	Name
XM_017010021.1	XP_016865510.1	T-cell immunoglobulin and mucin domain-containing protein 4 isoform X1
NM_001146726.1	NP_001140198.1	T-cell immunoglobulin and mucin domain-containing protein 4 isoform 2 precursor
NM_138379.3	NP_612388.2	T-cell immunoglobulin and mucin domain-containing protein 4 isoform 1 precursor
NM_001146726.2	NP_001140198.1	T-cell immunoglobulin and mucin domain-containing protein 4 isoform 2 precursor
XM_011534694.3	XP_011532996.1	T-cell immunoglobulin and mucin domain-containing protein 4 isoform X2
NM_138379.2	NP_612388.2	T-cell immunoglobulin and mucin domain-containing protein 4 isoform 1 precursor
XM_011534694.2	XP_011532996.1	T-cell immunoglobulin and mucin domain-containing protein 4 isoform X2
XM_017010021.2	XP_016865510.1	T-cell immunoglobulin and mucin domain-containing protein 4 isoform X1

Pathways from BioSystems

Homologies

	LOC715236	XP_002804642.1
Bos taurus (cattle)	TIMD4	NP_001068788.1
Canis lupus familiaris (dog)	TIMD4	XP_005619313.1
Rattus norvegicus (Norway rat)	Timd4	XP_006246235.1
Gallus gallus (chicken)	TIMD4	NP_001006149.1
Homo sapiens (human)	TIMD4	NP_612388.2
Mus musculus (house mouse)	Timd4	NP_848874.3
Pan troglodytes (chimpanzee)	TIMD4	XP_518057.2

Gene Ontology
Bibliography

Related articles in PubMed

Association between the
Zhang QH, Yin RX, Chen WX, Cao XL, Chen YM
Bioscience reports38(1)(2018 Feb)

Tim-4 expression increases in ischemic stroke patients and is associated with poor outcome.
Xu L, Ye Z, Wang B, Huang Y, Zhou L, Liu C, Chen D, Sun M, Dai F, Guan S, Tang W
Journal of neuroimmunology(2017 Dec)

The significance of TIMD4 expression in clear cell renal cell carcinoma.
Yano H, Motoshima T, Ma C, Pan C, Yamada S, Nakayama T, Kitada S, Fujimoto N, Kamba T, Takeya M, Komohara Y
Medical molecular morphology50(4)220-226(2017 Dec)

Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells.
Sims B, Farrow AL, Williams SD, Bansal A, Krendelchtchikov A, Gu L, Matthews QL
International journal of nanomedicine124823-4833(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study aimed to investigate the association of two TIM-4 SNPs) with systemic lupus erythematosus (SLE)susceptibility in a Chinese Han population.The results imply that GG genotype of the TIM-4 gene at -1419 site might be associated with the disease activity of SLE.
Title: Promoter polymorphisms of the TIM-4 gene are correlated with disease activity in patients with systemic lupus erythematosus.

Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells
Title: Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells.

analysis of the molecular characteristics of both mTIM-4 and hTIM-4 provides a better understanding of the regions of the TIM-4 IgV domain critical for Ebola virus entry
Title: Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry.

Tim-4 expression is closely associated with glioma and may have a regulatory role
Title: Expression of Tim4 in Glioma and its Regulatory Role in LN-18 Glioma Cells.

Data showed up-regulation of TIM-4 in lung cancer tissues and a correlation with poor prognosis. Also, TIM-4 was found to promote growth of lung cancer cells by its interaction with integrin alphavbeta3 through its RGD motif.
Title: TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner.

The following TIMD4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TIMD4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14785	NM_138379.3 Latest version!	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu14632	NM_001146726.2 Latest version!	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu74414	XM_011534694.3 Latest version!	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu96188	XM_017010021.2 Latest version!	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu14632	NM_001146726.1	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu14785	NM_138379.2	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu74414	XM_011534694.2	Homo sapiens T-cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu96188	XM_017010021.1	Homo sapiens T-cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TIMD4 ( NM_138379.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_612388.2 Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14785
Clone ID Related Accession (Same CDS sequence)	NM_138379.3 , NM_138379.2
Accession Version	NM_138379.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	T-cell immunoglobulin and mucin domain-containing protein 4 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008988.1, AC008491.6 and AA843555.1. On Nov 23, 2018 this sequence version replaced NM_138379.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189664.3602.1, SRR5189664.461.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000274532.7/ ENSP00000274532.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG AGTCCAAAGT TTGGGATCTC 
CCATCAACAT CCCACGTGTC AATGTGGAAA ACGAGTGATT CTGTGTCTTC TCCTCAGCCT 
GGAGCATCTG ATACAGCAGT TCCTGAGCAG AACAAAACAA CAAAAACAGG ACAGATGGAT 
GGAATACCCA TGTCAATGAA GAATGAAATG CCCATCTCCC AACTACTGAT GATCATCGCC 
CCCTCCTTGG GATTTGTGCT CTTCGCATTG TTTGTGGCGT TTCTCCTGAG AGGGAAACTC 
ATGGAAACCT ATTGTTCGCA GAAACACACA AGGCTAGACT ACATTGGAGA TAGTAAAAAT 
GTCCTCAATG ACGTGCAGCA TGGAAGGGAA GACGAAGACG GCCTTTTTAC CCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612388.2
CDS	29..1165
Translation	MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSVESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDSVSSPQPGASDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKNVLNDVQHGREDEDGLFTL

Target ORF information:

RefSeq Version	NM_138379.3
Organism	Homo sapiens(human)
Definition	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138379.3

ORF Insert Sequence:

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG AGTCCAAAGT TTGGGATCTC 
CCATCAACAT CCCACGTGTC AATGTGGAAA ACGAGTGATT CTGTGTCTTC TCCTCAGCCT 
GGAGCATCTG ATACAGCAGT TCCTGAGCAG AACAAAACAA CAAAAACAGG ACAGATGGAT 
GGAATACCCA TGTCAATGAA GAATGAAATG CCCATCTCCC AACTACTGAT GATCATCGCC 
CCCTCCTTGG GATTTGTGCT CTTCGCATTG TTTGTGGCGT TTCTCCTGAG AGGGAAACTC 
ATGGAAACCT ATTGTTCGCA GAAACACACA AGGCTAGACT ACATTGGAGA TAGTAAAAAT 
GTCCTCAATG ACGTGCAGCA TGGAAGGGAA GACGAAGACG GCCTTTTTAC CCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIMD4 ( NM_138379.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_612388.2 Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14785
Clone ID Related Accession (Same CDS sequence)	NM_138379.3 , NM_138379.2
Accession Version	NM_138379.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	T-cell immunoglobulin and mucin domain-containing protein 4 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008988.1, AC008491.6 and AA843555.1. On Apr 11, 2009 this sequence version replaced NM_138379.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC008988.1, AK312746.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG AGTCCAAAGT TTGGGATCTC 
CCATCAACAT CCCACGTGTC AATGTGGAAA ACGAGTGATT CTGTGTCTTC TCCTCAGCCT 
GGAGCATCTG ATACAGCAGT TCCTGAGCAG AACAAAACAA CAAAAACAGG ACAGATGGAT 
GGAATACCCA TGTCAATGAA GAATGAAATG CCCATCTCCC AACTACTGAT GATCATCGCC 
CCCTCCTTGG GATTTGTGCT CTTCGCATTG TTTGTGGCGT TTCTCCTGAG AGGGAAACTC 
ATGGAAACCT ATTGTTCGCA GAAACACACA AGGCTAGACT ACATTGGAGA TAGTAAAAAT 
GTCCTCAATG ACGTGCAGCA TGGAAGGGAA GACGAAGACG GCCTTTTTAC CCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612388.2
CDS	58..1194
Translation	MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSVESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDSVSSPQPGASDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKNVLNDVQHGREDEDGLFTL

Target ORF information:

RefSeq Version	NM_138379.2
Organism	Homo sapiens(human)
Definition	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138379.2

ORF Insert Sequence:

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG AGTCCAAAGT TTGGGATCTC 
CCATCAACAT CCCACGTGTC AATGTGGAAA ACGAGTGATT CTGTGTCTTC TCCTCAGCCT 
GGAGCATCTG ATACAGCAGT TCCTGAGCAG AACAAAACAA CAAAAACAGG ACAGATGGAT 
GGAATACCCA TGTCAATGAA GAATGAAATG CCCATCTCCC AACTACTGAT GATCATCGCC 
CCCTCCTTGG GATTTGTGCT CTTCGCATTG TTTGTGGCGT TTCTCCTGAG AGGGAAACTC 
ATGGAAACCT ATTGTTCGCA GAAACACACA AGGCTAGACT ACATTGGAGA TAGTAAAAAT 
GTCCTCAATG ACGTGCAGCA TGGAAGGGAA GACGAAGACG GCCTTTTTAC CCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIMD4 ( NM_001146726.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001140198.1 Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14632
Clone ID Related Accession (Same CDS sequence)	NM_001146726.1 , NM_001146726.2
Accession Version	NM_001146726.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-18
Organism	Homo sapiens(human)
Product	T-cell immunoglobulin and mucin domain-containing protein 4 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008988.1, AC026777.4, AC008491.6 and AA843555.1. Transcript Variant: This variant (2) lacks an exon in the coding region compared to variant 1. The encoded isoform (2) is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301337.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG CATCTGATAC AGCAGTTCCT 
GAGCAGAACA AAACAACAAA AACAGGACAG ATGGATGGAA TACCCATGTC AATGAAGAAT 
GAAATGCCCA TCTCCCAACT ACTGATGATC ATCGCCCCCT CCTTGGGATT TGTGCTCTTC 
GCATTGTTTG TGGCGTTTCT CCTGAGAGGG AAACTCATGG AAACCTATTG TTCGCAGAAA 
CACACAAGGC TAGACTACAT TGGAGATAGT AAAAATGTCC TCAATGACGT GCAGCATGGA 
AGGGAAGACG AAGACGGCCT TTTTACCCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001140198.1
CDS	58..1110
Translation	MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSVESTSADTVLLTSKASDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKNVLNDVQHGREDEDGLFTL

Target ORF information:

RefSeq Version	NM_001146726.1
Organism	Homo sapiens(human)
Definition	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001146726.1

ORF Insert Sequence:

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG CATCTGATAC AGCAGTTCCT 
GAGCAGAACA AAACAACAAA AACAGGACAG ATGGATGGAA TACCCATGTC AATGAAGAAT 
GAAATGCCCA TCTCCCAACT ACTGATGATC ATCGCCCCCT CCTTGGGATT TGTGCTCTTC 
GCATTGTTTG TGGCGTTTCT CCTGAGAGGG AAACTCATGG AAACCTATTG TTCGCAGAAA 
CACACAAGGC TAGACTACAT TGGAGATAGT AAAAATGTCC TCAATGACGT GCAGCATGGA 
AGGGAAGACG AAGACGGCCT TTTTACCCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIMD4 ( NM_001146726.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001140198.1 Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14632
Clone ID Related Accession (Same CDS sequence)	NM_001146726.1 , NM_001146726.2
Accession Version	NM_001146726.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	T-cell immunoglobulin and mucin domain-containing protein 4 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008988.1, AC026777.4, AC008491.6 and AA843555.1. On May 31, 2019 this sequence version replaced NM_001146726.1. Transcript Variant: This variant (2) lacks an exon in the coding region compared to variant 1. The encoded isoform (2) is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301337.1, SRR5189664.20329.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG CATCTGATAC AGCAGTTCCT 
GAGCAGAACA AAACAACAAA AACAGGACAG ATGGATGGAA TACCCATGTC AATGAAGAAT 
GAAATGCCCA TCTCCCAACT ACTGATGATC ATCGCCCCCT CCTTGGGATT TGTGCTCTTC 
GCATTGTTTG TGGCGTTTCT CCTGAGAGGG AAACTCATGG AAACCTATTG TTCGCAGAAA 
CACACAAGGC TAGACTACAT TGGAGATAGT AAAAATGTCC TCAATGACGT GCAGCATGGA 
AGGGAAGACG AAGACGGCCT TTTTACCCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001140198.1
CDS	29..1081
Translation	MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSVESTSADTVLLTSKASDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKNVLNDVQHGREDEDGLFTL

Target ORF information:

RefSeq Version	NM_001146726.2
Organism	Homo sapiens(human)
Definition	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001146726.2

ORF Insert Sequence:

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG CATCTGATAC AGCAGTTCCT 
GAGCAGAACA AAACAACAAA AACAGGACAG ATGGATGGAA TACCCATGTC AATGAAGAAT 
GAAATGCCCA TCTCCCAACT ACTGATGATC ATCGCCCCCT CCTTGGGATT TGTGCTCTTC 
GCATTGTTTG TGGCGTTTCT CCTGAGAGGG AAACTCATGG AAACCTATTG TTCGCAGAAA 
CACACAAGGC TAGACTACAT TGGAGATAGT AAAAATGTCC TCAATGACGT GCAGCATGGA 
AGGGAAGACG AAGACGGCCT TTTTACCCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIMD4 ( XM_011534694.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011532996.1 Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu74414
Clone ID Related Accession (Same CDS sequence)	XM_011534694.3 , XM_011534694.2
Accession Version	XM_011534694.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	T-cell immunoglobulin and mucin domain-containing protein 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011534694.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG AGTCCAAAGT TTGGGATCTC 
CCATCAACAT CCCACGTGTC AATGTGGAAA ACGAGTGATT CTGTGTCTTC TCCTCAGCCT 
GGAGAGATGA GTTCTCACCA TGTTGCCCAG GCTGGTCTCA AATCTCTTGG CCTCAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532996.1
CDS	29..928
Translation	MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSVESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDSVSSPQPGEMSSHHVAQAGLKSLGLK

Target ORF information:

RefSeq Version	XM_011534694.3
Organism	Homo sapiens(human)
Definition	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534694.3

ORF Insert Sequence:

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG AGTCCAAAGT TTGGGATCTC 
CCATCAACAT CCCACGTGTC AATGTGGAAA ACGAGTGATT CTGTGTCTTC TCCTCAGCCT 
GGAGAGATGA GTTCTCACCA TGTTGCCCAG GCTGGTCTCA AATCTCTTGG CCTCAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIMD4 ( XM_011534694.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011532996.1 Homo sapiens T-cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu74414
Clone ID Related Accession (Same CDS sequence)	XM_011534694.3 , XM_011534694.2
Accession Version	XM_011534694.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	T-cell immunoglobulin and mucin domain-containing protein 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534694.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG AGTCCAAAGT TTGGGATCTC 
CCATCAACAT CCCACGTGTC AATGTGGAAA ACGAGTGATT CTGTGTCTTC TCCTCAGCCT 
GGAGAGATGA GTTCTCACCA TGTTGCCCAG GCTGGTCTCA AATCTCTTGG CCTCAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532996.1
CDS	29..928
Translation	MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSVESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDSVSSPQPGEMSSHHVAQAGLKSLGLK

Target ORF information:

RefSeq Version	XM_011534694.2
Organism	Homo sapiens(human)
Definition	Homo sapiens T-cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534694.2

ORF Insert Sequence:

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGA ATCAGAAACT GTCCTCCCCA GTGATTCCTG GAGTAGTGTT 
GAGTCTACTT CTGCTGACAC TGTCCTGCTG ACATCCAAAG AGTCCAAAGT TTGGGATCTC 
CCATCAACAT CCCACGTGTC AATGTGGAAA ACGAGTGATT CTGTGTCTTC TCCTCAGCCT 
GGAGAGATGA GTTCTCACCA TGTTGCCCAG GCTGGTCTCA AATCTCTTGG CCTCAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIMD4 ( XM_017010021.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865510.1 Homo sapiens T-cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu96188
Clone ID Related Accession (Same CDS sequence)	XM_017010021.1 , XM_017010021.2
Accession Version	XM_017010021.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	T-cell immunoglobulin and mucin domain-containing protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGC ATCTGATACA GCAGTTCCTG AGCAGAACAA AACAACAAAA 
ACAGGACAGA TGGATGGAAT ACCCATGTCA ATGAAGAATG AAATGCCCAT CTCCCAACTA 
CTGATGATCA TCGCCCCCTC CTTGGGATTT GTGCTCTTCG CATTGTTTGT GGCGTTTCTC 
CTGAGAGGGA AACTCATGGA AACCTATTGT TCGCAGAAAC ACACAAGGCT AGACTACATT 
GGAGATAGTA AAAATGTCCT CAATGACGTG CAGCATGGAA GGGAAGACGA AGACGGCCTT 
TTTACCCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865510.1
CDS	29..1000
Translation	MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAASDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKNVLNDVQHGREDEDGLFTL

Target ORF information:

RefSeq Version	XM_017010021.1
Organism	Homo sapiens(human)
Definition	Homo sapiens T-cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010021.1

ORF Insert Sequence:

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGC ATCTGATACA GCAGTTCCTG AGCAGAACAA AACAACAAAA 
ACAGGACAGA TGGATGGAAT ACCCATGTCA ATGAAGAATG AAATGCCCAT CTCCCAACTA 
CTGATGATCA TCGCCCCCTC CTTGGGATTT GTGCTCTTCG CATTGTTTGT GGCGTTTCTC 
CTGAGAGGGA AACTCATGGA AACCTATTGT TCGCAGAAAC ACACAAGGCT AGACTACATT 
GGAGATAGTA AAAATGTCCT CAATGACGTG CAGCATGGAA GGGAAGACGA AGACGGCCTT 
TTTACCCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIMD4 ( XM_017010021.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865510.1 Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu96188
Clone ID Related Accession (Same CDS sequence)	XM_017010021.1 , XM_017010021.2
Accession Version	XM_017010021.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	T-cell immunoglobulin and mucin domain-containing protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017010021.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGC ATCTGATACA GCAGTTCCTG AGCAGAACAA AACAACAAAA 
ACAGGACAGA TGGATGGAAT ACCCATGTCA ATGAAGAATG AAATGCCCAT CTCCCAACTA 
CTGATGATCA TCGCCCCCTC CTTGGGATTT GTGCTCTTCG CATTGTTTGT GGCGTTTCTC 
CTGAGAGGGA AACTCATGGA AACCTATTGT TCGCAGAAAC ACACAAGGCT AGACTACATT 
GGAGATAGTA AAAATGTCCT CAATGACGTG CAGCATGGAA GGGAAGACGA AGACGGCCTT 
TTTACCCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865510.1
CDS	29..1000
Translation	MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAASDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKNVLNDVQHGREDEDGLFTL

Target ORF information:

RefSeq Version	XM_017010021.2
Organism	Homo sapiens(human)
Definition	Homo sapiens T cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010021.2

ORF Insert Sequence:

ATGTCCAAAG AACCTCTCAT TCTCTGGCTG ATGATTGAGT TTTGGTGGCT TTACCTGACA 
CCAGTCACTT CAGAGACTGT TGTGACGGAG GTTTTGGGTC ACCGGGTGAC TTTGCCCTGT 
CTGTACTCAT CCTGGTCTCA CAACAGCAAC AGCATGTGCT GGGGGAAAGA CCAGTGCCCC 
TACTCCGGTT GCAAGGAGGC GCTCATCCGC ACTGATGGAA TGAGGGTGAC CTCAAGAAAG 
TCAGCAAAAT ATAGACTTCA GGGGACTATC CCGAGAGGTG ATGTCTCCTT GACCATCTTA 
AACCCCAGTG AAAGTGACAG CGGTGTGTAC TGCTGCCGCA TAGAAGTGCC TGGCTGGTTC 
AACGATGTAA AGATAAACGT GCGCCTGAAT CTACAGAGAG CCTCAACAAC CACGCACAGA 
ACAGCAACCA CCACCACACG CAGAACAACA ACAACAAGCC CCACCACCAC CCGACAAATG 
ACAACAACCC CAGCTGCACT TCCAACAACA GTCGTGACCA CACCCGATCT CACAACCGGA 
ACACCACTCC AGATGACAAC CATTGCCGTC TTCACAACAG CAAACACGTG CCTTTCACTA 
ACCCCAAGCA CCCTTCCGGA GGAAGCCACA GGTCTTCTGA CTCCCGAGCC TTCTAAGGAA 
GGGCCCATCC TCACTGCAGC ATCTGATACA GCAGTTCCTG AGCAGAACAA AACAACAAAA 
ACAGGACAGA TGGATGGAAT ACCCATGTCA ATGAAGAATG AAATGCCCAT CTCCCAACTA 
CTGATGATCA TCGCCCCCTC CTTGGGATTT GTGCTCTTCG CATTGTTTGT GGCGTTTCTC 
CTGAGAGGGA AACTCATGGA AACCTATTGT TCGCAGAAAC ACACAAGGCT AGACTACATT 
GGAGATAGTA AAAATGTCCT CAATGACGTG CAGCATGGAA GGGAAGACGA AGACGGCCTT 
TTTACCCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association between the
Bioscience reports38(1)(2018 Feb)
Zhang QH,Yin RX,Chen WX,Cao XL,Chen YM

Tim-4 expression increases in ischemic stroke patients and is associated with poor outcome.
Journal of neuroimmunology(2017 Dec)
Xu L,Ye Z,Wang B,Huang Y,Zhou L,Liu C,Chen D,Sun M,Dai F,Guan S,Tang W

The significance of TIMD4 expression in clear cell renal cell carcinoma.
Medical molecular morphology50(4)220-226(2017 Dec)
Yano H,Motoshima T,Ma C,Pan C,Yamada S,Nakayama T,Kitada S,Fujimoto N,Kamba T,Takeya M,Komohara Y

Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells.
International journal of nanomedicine124823-4833(2017)
Sims B,Farrow AL,Williams SD,Bansal A,Krendelchtchikov A,Gu L,Matthews QL

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TIMD4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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