HGS cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HGS
Entrez Gene ID	9146
Full Name	hepatocyte growth factor-regulated tyrosine kinase substrate
Synonyms	HRS
General protein information	Preferred Names hepatocyte growth factor-regulated tyrosine kinase substrate Names hepatocyte growth factor-regulated tyrosine kinase substrate human growth factor-regulated tyrosine kinase substrate protein pp110
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.3
Summary	The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010].
Disorder MIM:	604375

mRNA and Protein(s)

mRNA	Protein	Name
XM_024451024.1	XP_024306792.1	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3
XM_017025298.1	XP_016880787.1	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X4
NM_004712.4	NP_004703.1	hepatocyte growth factor-regulated tyrosine kinase substrate
XM_024451025.1	XP_024306793.1	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3
NM_004712.5	NP_004703.1	hepatocyte growth factor-regulated tyrosine kinase substrate
XM_017025297.1	XP_016880786.1	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X2
XM_011525463.2	XP_011523765.1	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1

Pathways from BioSystems

Homologies

	HGS	XP_001111673.1
Bos taurus (cattle)	HGS	NP_001039554.1
Danio rerio (zebrafish)	hgs	NP_956162.1
Caenorhabditis elegans (roundworm)	hgrs-1	NP_501375.2
Canis lupus familiaris (dog)	HGS	XP_005624060.1
Mus musculus (house mouse)	Hgs	NP_001152800.1
Gallus gallus (chicken)	HGS	XP_426233.3
Drosophila melanogaster (fruit fly)	Hrs	NP_525099.3
Pan troglodytes (chimpanzee)	HGS	XP_511742.4
Rattus norvegicus (Norway rat)	Hgs	NP_062260.2
Xenopus tropicalis (tropical clawed frog)	hgs	NP_001016513.1
Homo sapiens (human)	HGS	NP_004703.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008887	XP_319634.4

Gene Ontology
Bibliography

Related articles in PubMed

The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor.
Roux BT, Bauer CC, McNeish AJ, Ward SG, Cottrell GS
Scientific reports7(1)12389(2017 Sep)

ESCRT-0 Component Hrs Promotes Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus in Human Dermal Microvascular Endothelial Cells.
Veettil MV, Kumar B, Ansari MA, Dutta D, Iqbal J, Gjyshi O, Bottero V, Chandran B
Journal of virology90(8)3860-72(2016 Apr)

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

detailed analysis of the subcellular localization and functional significance of Hrs in macropinocytosis-mediated entry of Kaposi's Sarcoma-Associated Herpesvirus
Title: ESCRT-0 Component Hrs Promotes Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus in Human Dermal Microvascular Endothelial Cells.

Results demonstrate the existence of crosstalk between beta-catenin signaling and HGS in two different types of cancer (hepatoblastoma and colorectal).
Title: A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1.

ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
Title: ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.

we identified an interaction between EsxH, which is secreted by the Esx-3 TSSS, and human hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs/Hrs), a component of the endosomal sorting complex required for transport (ESCRT).
Title: Mycobacterium tuberculosis type VII secreted effector EsxH targets host ESCRT to impair trafficking.

the role for tumoral c-Met expression or sMet/HGF levels as upfront selection criterion or predictive biomarkers deserve further study in this emerging area of therapeutic focus in RCC
Title: Targeting the hepatocyte growth factor/c-Met signaling pathway in renal cell carcinoma.

The following HGS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HGS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09360	NM_004712.5 Latest version!	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu104497	XM_024451025.1 Latest version!	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu104497	XM_024451024.1 Latest version!	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu50793	XM_017025297.1 Latest version!	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu62516	XM_011525463.2 Latest version!	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu62517	XM_017025298.1 Latest version!	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu09360	NM_004712.4	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HGS ( NM_004712.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004703.1 Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), mRNA.

Price & Availability↑

CloneID	OHu09360
Clone ID Related Accession (Same CDS sequence)	NM_004712.4 , NM_004712.5
Accession Version	NM_004712.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	hepatocyte growth factor-regulated tyrosine kinase substrate
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR001213.1, BC003565.1 and AI365104.1. On Dec 17, 2010 this sequence version replaced NM_004712.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.240659.1, BC003565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AGGCGACCAG CCAGCTCCTG 
TTGGAGACAG ATTGGGAGTC CATTTTGCAG ATCTGCGACC TGATCCGCCA AGGGGACACA 
CAAGCAAAAT ATGCTGTGAA TTCCATCAAG AAGAAAGTCA ACGACAAGAA CCCACACGTC 
GCCTTGTATG CCCTGGAGGT CATGGAATCT GTGGTAAAGA ACTGTGGCCA GACAGTTCAT 
GATGAGGTGG CCAACAAGCA GACCATGGAG GAGCTGAAGG ACCTGCTGAA GAGACAAGTG 
GAGGTAAACG TCCGTAACAA GATCCTGTAC CTGATCCAGG CCTGGGCGCA TGCCTTCCGG 
AACGAGCCCA AGTACAAGGT GGTCCAGGAC ACCTACCAGA TCATGAAGGT GGAGGGGCAC 
GTCTTTCCAG AATTCAAAGA GAGCGATGCC ATGTTTGCTG CCGAGAGAGC CCCAGACTGG 
GTGGACGCTG AGGAATGCCA CCGCTGCAGG GTGCAGTTCG GGGTGATGAC CCGTAAGCAC 
CACTGCCGGG CGTGTGGGCA GATATTCTGT GGAAAGTGTT CTTCCAAGTA CTCCACCATC 
CCCAAGTTTG GCATCGAGAA GGAGGTGCGC GTGTGTGAGC CCTGCTACGA GCAGCTGAAC 
AGGAAAGCGG AGGGAAAGGC CACTTCCACC ACTGAGCTGC CCCCCGAGTA CCTGACCAGC 
CCCCTGTCTC AGCAGTCCCA GCTGCCCCCC AAGAGGGACG AGACGGCCCT GCAGGAGGAG 
GAGGAGCTGC AGCTGGCCCT GGCGCTGTCA CAGTCAGAGG CGGAGGAGAA GGAGAGGCTG 
AGACAGAAGT CCACGTACAC TTCGTACCCC AAGGCGGAGC CCATGCCCTC GGCCTCCTCA 
GCGCCCCCCG CCAGCAGCCT GTACTCTTCA CCTGTGAACT CGTCGGCGCC TCTGGCTGAG 
GACATCGACC CTGAGCTCGC ACGGTATCTC AACCGGAACT ACTGGGAGAA GAAGCAGGAG 
GAGGCTCGCA AGAGCCCCAC GCCATCTGCG CCCGTGCCCC TGACGGAGCC GGCTGCACAG 
CCTGGGGAAG GGCACGCAGC CCCCACCAAC GTGGTGGAGA ACCCCCTCCC GGAGACAGAC 
TCTCAGCCCA TTCCTCCCTC TGGTGGCCCC TTTAGTGAGC CACAGTTCCA CAATGGCGAG 
TCTGAGGAGA GCCACGAGCA GTTCCTGAAG GCGCTGCAGA ACGCCGTCAC CACCTTCGTG 
AACCGCATGA AGAGTAACCA CATGCGGGGC CGCAGCATCA CCAATGACTC GGCCGTGCTC 
TCACTCTTCC AGTCCATCAA CGGCATGCAC CCGCAGCTGC TGGAGCTGCT CAACCAGCTG 
GACGAGCGCA GGCTGTACTA TGAGGGGCTG CAGGACAAGC TGGCACAGAT CCGCGATGCC 
CGGGGGGCGC TGAGTGCCCT GCGCGAAGAG CACCGGGAGA AGCTTCGCCG GGCAGCCGAG 
GAGGCAGAGC GCCAGCGCCA GATCCAGCTG GCCCAGAAGC TGGAGATAAT GCGGCAGAAG 
AAGCAGGAGT ACCTGGAGGT GCAGAGGCAG CTGGCCATCC AGCGCCTGCA GGAGCAGGAG 
AAGGAGCGGC AGATGCGGCT GGAGCAGCAG AAGCAGACGG TCCAGATGCG CGCGCAGATG 
CCCGCCTTCC CCCTGCCCTA CGCCCAGCTC CAGGCCATGC CCGCAGCCGG AGGTGTGCTC 
TACCAGCCCT CGGGACCAGC CAGCTTCCCC AGCACCTTCA GCCCTGCCGG CTCGGTGGAG 
GGCTCCCCAA TGCACGGCGT GTACATGAGC CAGCCGGCCC CTGCCGCTGG CCCCTACCCC 
AGCATGCCCA GCACTGCGGC TGATCCCAGC ATGGTGAGTG CCTACATGTA CCCAGCAGGG 
GCCACTGGGG CGCAGGCGGC CCCCCAGGCC CAGGCCGGAC CCACCGCCAG CCCCGCTTAC 
TCATCCTACC AGCCTACTCC CACAGCGGGC TACCAGAACG TGGCCTCCCA GGCCCCACAG 
AGCCTCCCGG CCATCTCTCA GCCTCCGCAG TCCAGCACCA TGGGCTACAT GGGGAGCCAG 
TCAGTCTCCA TGGGCTACCA GCCTTACAAC ATGCAGAATC TCATGACCAC CCTCCCAAGC 
CAGGATGCGT CTCTGCCACC CCAGCAGCCC TACATCGCGG GGCAGCAGCC CATGTACCAG 
CAGATGGCAC CCTCTGGCGG TCCCCCCCAG CAGCAGCCCC CCGTGGCCCA GCAACCGCAG 
GCACAGGGGC CGCCGGCACA GGGCAGCGAG GCCCAGCTCA TTTCATTCGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004703.1
CDS	136..2469
Translation	MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD

Target ORF information:

RefSeq Version	NM_004712.4
Organism	Homo sapiens(human)
Definition	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004712.4

ORF Insert Sequence:

ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AGGCGACCAG CCAGCTCCTG 
TTGGAGACAG ATTGGGAGTC CATTTTGCAG ATCTGCGACC TGATCCGCCA AGGGGACACA 
CAAGCAAAAT ATGCTGTGAA TTCCATCAAG AAGAAAGTCA ACGACAAGAA CCCACACGTC 
GCCTTGTATG CCCTGGAGGT CATGGAATCT GTGGTAAAGA ACTGTGGCCA GACAGTTCAT 
GATGAGGTGG CCAACAAGCA GACCATGGAG GAGCTGAAGG ACCTGCTGAA GAGACAAGTG 
GAGGTAAACG TCCGTAACAA GATCCTGTAC CTGATCCAGG CCTGGGCGCA TGCCTTCCGG 
AACGAGCCCA AGTACAAGGT GGTCCAGGAC ACCTACCAGA TCATGAAGGT GGAGGGGCAC 
GTCTTTCCAG AATTCAAAGA GAGCGATGCC ATGTTTGCTG CCGAGAGAGC CCCAGACTGG 
GTGGACGCTG AGGAATGCCA CCGCTGCAGG GTGCAGTTCG GGGTGATGAC CCGTAAGCAC 
CACTGCCGGG CGTGTGGGCA GATATTCTGT GGAAAGTGTT CTTCCAAGTA CTCCACCATC 
CCCAAGTTTG GCATCGAGAA GGAGGTGCGC GTGTGTGAGC CCTGCTACGA GCAGCTGAAC 
AGGAAAGCGG AGGGAAAGGC CACTTCCACC ACTGAGCTGC CCCCCGAGTA CCTGACCAGC 
CCCCTGTCTC AGCAGTCCCA GCTGCCCCCC AAGAGGGACG AGACGGCCCT GCAGGAGGAG 
GAGGAGCTGC AGCTGGCCCT GGCGCTGTCA CAGTCAGAGG CGGAGGAGAA GGAGAGGCTG 
AGACAGAAGT CCACGTACAC TTCGTACCCC AAGGCGGAGC CCATGCCCTC GGCCTCCTCA 
GCGCCCCCCG CCAGCAGCCT GTACTCTTCA CCTGTGAACT CGTCGGCGCC TCTGGCTGAG 
GACATCGACC CTGAGCTCGC ACGGTATCTC AACCGGAACT ACTGGGAGAA GAAGCAGGAG 
GAGGCTCGCA AGAGCCCCAC GCCATCTGCG CCCGTGCCCC TGACGGAGCC GGCTGCACAG 
CCTGGGGAAG GGCACGCAGC CCCCACCAAC GTGGTGGAGA ACCCCCTCCC GGAGACAGAC 
TCTCAGCCCA TTCCTCCCTC TGGTGGCCCC TTTAGTGAGC CACAGTTCCA CAATGGCGAG 
TCTGAGGAGA GCCACGAGCA GTTCCTGAAG GCGCTGCAGA ACGCCGTCAC CACCTTCGTG 
AACCGCATGA AGAGTAACCA CATGCGGGGC CGCAGCATCA CCAATGACTC GGCCGTGCTC 
TCACTCTTCC AGTCCATCAA CGGCATGCAC CCGCAGCTGC TGGAGCTGCT CAACCAGCTG 
GACGAGCGCA GGCTGTACTA TGAGGGGCTG CAGGACAAGC TGGCACAGAT CCGCGATGCC 
CGGGGGGCGC TGAGTGCCCT GCGCGAAGAG CACCGGGAGA AGCTTCGCCG GGCAGCCGAG 
GAGGCAGAGC GCCAGCGCCA GATCCAGCTG GCCCAGAAGC TGGAGATAAT GCGGCAGAAG 
AAGCAGGAGT ACCTGGAGGT GCAGAGGCAG CTGGCCATCC AGCGCCTGCA GGAGCAGGAG 
AAGGAGCGGC AGATGCGGCT GGAGCAGCAG AAGCAGACGG TCCAGATGCG CGCGCAGATG 
CCCGCCTTCC CCCTGCCCTA CGCCCAGCTC CAGGCCATGC CCGCAGCCGG AGGTGTGCTC 
TACCAGCCCT CGGGACCAGC CAGCTTCCCC AGCACCTTCA GCCCTGCCGG CTCGGTGGAG 
GGCTCCCCAA TGCACGGCGT GTACATGAGC CAGCCGGCCC CTGCCGCTGG CCCCTACCCC 
AGCATGCCCA GCACTGCGGC TGATCCCAGC ATGGTGAGTG CCTACATGTA CCCAGCAGGG 
GCCACTGGGG CGCAGGCGGC CCCCCAGGCC CAGGCCGGAC CCACCGCCAG CCCCGCTTAC 
TCATCCTACC AGCCTACTCC CACAGCGGGC TACCAGAACG TGGCCTCCCA GGCCCCACAG 
AGCCTCCCGG CCATCTCTCA GCCTCCGCAG TCCAGCACCA TGGGCTACAT GGGGAGCCAG 
TCAGTCTCCA TGGGCTACCA GCCTTACAAC ATGCAGAATC TCATGACCAC CCTCCCAAGC 
CAGGATGCGT CTCTGCCACC CCAGCAGCCC TACATCGCGG GGCAGCAGCC CATGTACCAG 
CAGATGGCAC CCTCTGGCGG TCCCCCCCAG CAGCAGCCCC CCGTGGCCCA GCAACCGCAG 
GCACAGGGGC CGCCGGCACA GGGCAGCGAG GCCCAGCTCA TTTCATTCGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HGS ( NM_004712.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_004703.1 Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), mRNA.

Price & Availability↑

CloneID	OHu09360
Clone ID Related Accession (Same CDS sequence)	NM_004712.4 , NM_004712.5
Accession Version	NM_004712.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	hepatocyte growth factor-regulated tyrosine kinase substrate
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC003565.1 and AI365104.1. On Nov 22, 2018 this sequence version replaced NM_004712.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.27635.1, D84064.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000329138.9/ ENSP00000331201.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AGGCGACCAG CCAGCTCCTG 
TTGGAGACAG ATTGGGAGTC CATTTTGCAG ATCTGCGACC TGATCCGCCA AGGGGACACA 
CAAGCAAAAT ATGCTGTGAA TTCCATCAAG AAGAAAGTCA ACGACAAGAA CCCACACGTC 
GCCTTGTATG CCCTGGAGGT CATGGAATCT GTGGTAAAGA ACTGTGGCCA GACAGTTCAT 
GATGAGGTGG CCAACAAGCA GACCATGGAG GAGCTGAAGG ACCTGCTGAA GAGACAAGTG 
GAGGTAAACG TCCGTAACAA GATCCTGTAC CTGATCCAGG CCTGGGCGCA TGCCTTCCGG 
AACGAGCCCA AGTACAAGGT GGTCCAGGAC ACCTACCAGA TCATGAAGGT GGAGGGGCAC 
GTCTTTCCAG AATTCAAAGA GAGCGATGCC ATGTTTGCTG CCGAGAGAGC CCCAGACTGG 
GTGGACGCTG AGGAATGCCA CCGCTGCAGG GTGCAGTTCG GGGTGATGAC CCGTAAGCAC 
CACTGCCGGG CGTGTGGGCA GATATTCTGT GGAAAGTGTT CTTCCAAGTA CTCCACCATC 
CCCAAGTTTG GCATCGAGAA GGAGGTGCGC GTGTGTGAGC CCTGCTACGA GCAGCTGAAC 
AGGAAAGCGG AGGGAAAGGC CACTTCCACC ACTGAGCTGC CCCCCGAGTA CCTGACCAGC 
CCCCTGTCTC AGCAGTCCCA GCTGCCCCCC AAGAGGGACG AGACGGCCCT GCAGGAGGAG 
GAGGAGCTGC AGCTGGCCCT GGCGCTGTCA CAGTCAGAGG CGGAGGAGAA GGAGAGGCTG 
AGACAGAAGT CCACGTACAC TTCGTACCCC AAGGCGGAGC CCATGCCCTC GGCCTCCTCA 
GCGCCCCCCG CCAGCAGCCT GTACTCTTCA CCTGTGAACT CGTCGGCGCC TCTGGCTGAG 
GACATCGACC CTGAGCTCGC ACGGTATCTC AACCGGAACT ACTGGGAGAA GAAGCAGGAG 
GAGGCTCGCA AGAGCCCCAC GCCATCTGCG CCCGTGCCCC TGACGGAGCC GGCTGCACAG 
CCTGGGGAAG GGCACGCAGC CCCCACCAAC GTGGTGGAGA ACCCCCTCCC GGAGACAGAC 
TCTCAGCCCA TTCCTCCCTC TGGTGGCCCC TTTAGTGAGC CACAGTTCCA CAATGGCGAG 
TCTGAGGAGA GCCACGAGCA GTTCCTGAAG GCGCTGCAGA ACGCCGTCAC CACCTTCGTG 
AACCGCATGA AGAGTAACCA CATGCGGGGC CGCAGCATCA CCAATGACTC GGCCGTGCTC 
TCACTCTTCC AGTCCATCAA CGGCATGCAC CCGCAGCTGC TGGAGCTGCT CAACCAGCTG 
GACGAGCGCA GGCTGTACTA TGAGGGGCTG CAGGACAAGC TGGCACAGAT CCGCGATGCC 
CGGGGGGCGC TGAGTGCCCT GCGCGAAGAG CACCGGGAGA AGCTTCGCCG GGCAGCCGAG 
GAGGCAGAGC GCCAGCGCCA GATCCAGCTG GCCCAGAAGC TGGAGATAAT GCGGCAGAAG 
AAGCAGGAGT ACCTGGAGGT GCAGAGGCAG CTGGCCATCC AGCGCCTGCA GGAGCAGGAG 
AAGGAGCGGC AGATGCGGCT GGAGCAGCAG AAGCAGACGG TCCAGATGCG CGCGCAGATG 
CCCGCCTTCC CCCTGCCCTA CGCCCAGCTC CAGGCCATGC CCGCAGCCGG AGGTGTGCTC 
TACCAGCCCT CGGGACCAGC CAGCTTCCCC AGCACCTTCA GCCCTGCCGG CTCGGTGGAG 
GGCTCCCCAA TGCACGGCGT GTACATGAGC CAGCCGGCCC CTGCCGCTGG CCCCTACCCC 
AGCATGCCCA GCACTGCGGC TGATCCCAGC ATGGTGAGTG CCTACATGTA CCCAGCAGGG 
GCCACTGGGG CGCAGGCGGC CCCCCAGGCC CAGGCCGGAC CCACCGCCAG CCCCGCTTAC 
TCATCCTACC AGCCTACTCC CACAGCGGGC TACCAGAACG TGGCCTCCCA GGCCCCACAG 
AGCCTCCCGG CCATCTCTCA GCCTCCGCAG TCCAGCACCA TGGGCTACAT GGGGAGCCAG 
TCAGTCTCCA TGGGCTACCA GCCTTACAAC ATGCAGAATC TCATGACCAC CCTCCCAAGC 
CAGGATGCGT CTCTGCCACC CCAGCAGCCC TACATCGCGG GGCAGCAGCC CATGTACCAG 
CAGATGGCAC CCTCTGGCGG TCCCCCCCAG CAGCAGCCCC CCGTGGCCCA GCAACCGCAG 
GCACAGGGGC CGCCGGCACA GGGCAGCGAG GCCCAGCTCA TTTCATTCGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004703.1
CDS	57..2390
Translation	MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD

Target ORF information:

RefSeq Version	NM_004712.5
Organism	Homo sapiens(human)
Definition	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004712.5

ORF Insert Sequence:

ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AGGCGACCAG CCAGCTCCTG 
TTGGAGACAG ATTGGGAGTC CATTTTGCAG ATCTGCGACC TGATCCGCCA AGGGGACACA 
CAAGCAAAAT ATGCTGTGAA TTCCATCAAG AAGAAAGTCA ACGACAAGAA CCCACACGTC 
GCCTTGTATG CCCTGGAGGT CATGGAATCT GTGGTAAAGA ACTGTGGCCA GACAGTTCAT 
GATGAGGTGG CCAACAAGCA GACCATGGAG GAGCTGAAGG ACCTGCTGAA GAGACAAGTG 
GAGGTAAACG TCCGTAACAA GATCCTGTAC CTGATCCAGG CCTGGGCGCA TGCCTTCCGG 
AACGAGCCCA AGTACAAGGT GGTCCAGGAC ACCTACCAGA TCATGAAGGT GGAGGGGCAC 
GTCTTTCCAG AATTCAAAGA GAGCGATGCC ATGTTTGCTG CCGAGAGAGC CCCAGACTGG 
GTGGACGCTG AGGAATGCCA CCGCTGCAGG GTGCAGTTCG GGGTGATGAC CCGTAAGCAC 
CACTGCCGGG CGTGTGGGCA GATATTCTGT GGAAAGTGTT CTTCCAAGTA CTCCACCATC 
CCCAAGTTTG GCATCGAGAA GGAGGTGCGC GTGTGTGAGC CCTGCTACGA GCAGCTGAAC 
AGGAAAGCGG AGGGAAAGGC CACTTCCACC ACTGAGCTGC CCCCCGAGTA CCTGACCAGC 
CCCCTGTCTC AGCAGTCCCA GCTGCCCCCC AAGAGGGACG AGACGGCCCT GCAGGAGGAG 
GAGGAGCTGC AGCTGGCCCT GGCGCTGTCA CAGTCAGAGG CGGAGGAGAA GGAGAGGCTG 
AGACAGAAGT CCACGTACAC TTCGTACCCC AAGGCGGAGC CCATGCCCTC GGCCTCCTCA 
GCGCCCCCCG CCAGCAGCCT GTACTCTTCA CCTGTGAACT CGTCGGCGCC TCTGGCTGAG 
GACATCGACC CTGAGCTCGC ACGGTATCTC AACCGGAACT ACTGGGAGAA GAAGCAGGAG 
GAGGCTCGCA AGAGCCCCAC GCCATCTGCG CCCGTGCCCC TGACGGAGCC GGCTGCACAG 
CCTGGGGAAG GGCACGCAGC CCCCACCAAC GTGGTGGAGA ACCCCCTCCC GGAGACAGAC 
TCTCAGCCCA TTCCTCCCTC TGGTGGCCCC TTTAGTGAGC CACAGTTCCA CAATGGCGAG 
TCTGAGGAGA GCCACGAGCA GTTCCTGAAG GCGCTGCAGA ACGCCGTCAC CACCTTCGTG 
AACCGCATGA AGAGTAACCA CATGCGGGGC CGCAGCATCA CCAATGACTC GGCCGTGCTC 
TCACTCTTCC AGTCCATCAA CGGCATGCAC CCGCAGCTGC TGGAGCTGCT CAACCAGCTG 
GACGAGCGCA GGCTGTACTA TGAGGGGCTG CAGGACAAGC TGGCACAGAT CCGCGATGCC 
CGGGGGGCGC TGAGTGCCCT GCGCGAAGAG CACCGGGAGA AGCTTCGCCG GGCAGCCGAG 
GAGGCAGAGC GCCAGCGCCA GATCCAGCTG GCCCAGAAGC TGGAGATAAT GCGGCAGAAG 
AAGCAGGAGT ACCTGGAGGT GCAGAGGCAG CTGGCCATCC AGCGCCTGCA GGAGCAGGAG 
AAGGAGCGGC AGATGCGGCT GGAGCAGCAG AAGCAGACGG TCCAGATGCG CGCGCAGATG 
CCCGCCTTCC CCCTGCCCTA CGCCCAGCTC CAGGCCATGC CCGCAGCCGG AGGTGTGCTC 
TACCAGCCCT CGGGACCAGC CAGCTTCCCC AGCACCTTCA GCCCTGCCGG CTCGGTGGAG 
GGCTCCCCAA TGCACGGCGT GTACATGAGC CAGCCGGCCC CTGCCGCTGG CCCCTACCCC 
AGCATGCCCA GCACTGCGGC TGATCCCAGC ATGGTGAGTG CCTACATGTA CCCAGCAGGG 
GCCACTGGGG CGCAGGCGGC CCCCCAGGCC CAGGCCGGAC CCACCGCCAG CCCCGCTTAC 
TCATCCTACC AGCCTACTCC CACAGCGGGC TACCAGAACG TGGCCTCCCA GGCCCCACAG 
AGCCTCCCGG CCATCTCTCA GCCTCCGCAG TCCAGCACCA TGGGCTACAT GGGGAGCCAG 
TCAGTCTCCA TGGGCTACCA GCCTTACAAC ATGCAGAATC TCATGACCAC CCTCCCAAGC 
CAGGATGCGT CTCTGCCACC CCAGCAGCCC TACATCGCGG GGCAGCAGCC CATGTACCAG 
CAGATGGCAC CCTCTGGCGG TCCCCCCCAG CAGCAGCCCC CCGTGGCCCA GCAACCGCAG 
GCACAGGGGC CGCCGGCACA GGGCAGCGAG GCCCAGCTCA TTTCATTCGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HGS ( XM_024451024.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306792.1 Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu104497
Clone ID Related Accession (Same CDS sequence)	XM_024451024.1 , XM_024451025.1
Accession Version	XM_024451024.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCTG TGGTAAAGAA CTGTGGCCAG ACAGTTCATG ATGAGGTGGC CAACAAGCAG 
ACCATGGAGG AGCTGAAGGA CCTGCTGAAG AGACAAGTGG AGGTAAACGT CCGTAACAAG 
ATCCTGTACC TGATCCAGGC CTGGGCGCAT GCCTTCCGGA ACGAGCCCAA GTACAAGGTG 
GTCCAGGACA CCTACCAGAT CATGAAGGTG GAGGGGCACG TCTTTCCAGA ATTCAAAGAG 
AGCGATGCCA TGTTTGCTGC CGAGAGAGCC CCAGACTGGG TGGACGCTGA GGAATGCCAC 
CGCTGCAGGG TGCAGTTCGG GGTGATGACC CGTAAGCACC ACTGCCGGGC GTGTGGGCAG 
ATATTCTGTG GAAAGTGTTC TTCCAAGTAC TCCACCATCC CCAAGTTTGG CATCGAGAAG 
GAGGTGCGCG TGTGTGAGCC CTGCTACGAG CAGCTGAACA GGAAAGCGGA GGGAAAGGCC 
ACTTCCACCA CTGAGCTGCC CCCCGAGTAC CTGACCAGCC CCCTGTCTCA GCAGTCCCAG 
CTGCCCCCCA AGAGGGACGA GACGGCCCTG CAGGAGGAGG AGGAGCTGCA GCTGGCCCTG 
GCGCTGTCAC AGTCAGAGGC GGAGGAGAAG GAGAGGCTGA GACAGAAGTC CACGTACACT 
TCGTACCCCA AGGCGGAGCC CATGCCCTCG GCCTCCTCAG CGCCCCCCGC CAGCAGCCTG 
TACTCTTCAC CTGTGAACTC GTCGGCGCCT CTGGCTGAGG ACATCGACCC TGAGCTCGCA 
CGGTATCTCA ACCGGAACTA CTGGGAGAAG AAGCAGGAGG AGGCTCGCAA GAGCCCCACG 
CCATCTGCGC CCGTGCCCCT GACGGAGCCG GCTGCACAGC CTGGGGAAGG GCACGCAGCC 
CCCACCAACG TGGTGGAGAA CCCCCTCCCG GAGACAGACT CTCAGCCCAT TCCTCCCTCT 
GGTGGCCCCT TTAGTGAGCC ACAGTTCCAC AATGGCGAGT CTGAGGAGAG CCACGAGCAG 
TTCCTGAAGG CGCTGCAGAA CGCCGTCACC ACCTTCGTGA ACCGCATGAA GAGTAACCAC 
ATGCGGGGCC GCAGCATCAC CAATGACTCG GCCGTGCTCT CACTCTTCCA GTCCATCAAC 
GGCATGCACC CGCAGCTGCT GGAGCTGCTC AACCAGCTGG ACGAGCGCAG GCTGTACTAT 
GAGGGGCTGC AGGACAAGCT GGCACAGATC CGCGATGCCC GGGGGGCGCT GAGTGCCCTG 
CGCGAAGAGC ACCGGGAGAA GCTTCGCCGG GCAGCCGAGG AGGCAGAGCG CCAGCGCCAG 
ATCCAGCTGG CCCAGAAGCT GGAGATAATG CGGCAGAAGA AGCAGGAGTA CCTGGAGGTG 
CAGAGGCAGC TGGCCATCCA GCGCCTGCAG GAGCAGGAGA AGGAGCGGCA GATGCGGCTG 
GAGCAGCAGA AGCAGACGGT CCAGATGCGC GCGCAGATGC CCGCCTTCCC CCTGCCCTAC 
GCCCAGCTCC AGGCCATGCC CGCAGCCGGA GGTGTGCTCT ACCAGCCCTC GGGACCAGCC 
AGCTTCCCCA GCACCTTCAG CCCTGCCGGC TCGGTGGAGG GCTCCCCAAT GCACGGCGTG 
TACATGAGCC AGCCGGCCCC TGCCGCTGGC CCCTACCCCA GCATGCCCAG CACTGCGGCT 
GATCCCAGCA TGGTGAGTGC CTACATGTAC CCAGCAGGGG CCACTGGGGC GCAGGCGGCC 
CCCCAGGCCC AGGCCGGACC CACCGCCAGC CCCGCTTACT CATCCTACCA GCCTACTCCC 
ACAGCGGGCT ACCAGAACGT GGCCTCCCAG GCCCCACAGA GCCTCCCGGC CATCTCTCAG 
CCTCCGCAGT CCAGCACCAT GGGCTACATG GGGAGCCAGT CAGTCTCCAT GGGCTACCAG 
CCTTACAACA TGCAGAATCT CATGACCACC CTCCCAAGCC AGGATGCGTC TCTGCCACCC 
CAGCAGCCCT ACATCGCGGG GCAGCAGCCC ATGTACCAGC AGATGGCACC CTCTGGCGGT 
CCCCCCCAGC AGCAGCCCCC CGTGGCCCAG CAACCGCAGG CACAGGGGCC GCCGGCACAG 
GGCAGCGAGG CCCAGCTCAT TTCATTCGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306792.1
CDS	842..2974
Translation	MESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD

Target ORF information:

RefSeq Version	XM_024451024.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451024.1

ORF Insert Sequence:

ATGGAATCTG TGGTAAAGAA CTGTGGCCAG ACAGTTCATG ATGAGGTGGC CAACAAGCAG 
ACCATGGAGG AGCTGAAGGA CCTGCTGAAG AGACAAGTGG AGGTAAACGT CCGTAACAAG 
ATCCTGTACC TGATCCAGGC CTGGGCGCAT GCCTTCCGGA ACGAGCCCAA GTACAAGGTG 
GTCCAGGACA CCTACCAGAT CATGAAGGTG GAGGGGCACG TCTTTCCAGA ATTCAAAGAG 
AGCGATGCCA TGTTTGCTGC CGAGAGAGCC CCAGACTGGG TGGACGCTGA GGAATGCCAC 
CGCTGCAGGG TGCAGTTCGG GGTGATGACC CGTAAGCACC ACTGCCGGGC GTGTGGGCAG 
ATATTCTGTG GAAAGTGTTC TTCCAAGTAC TCCACCATCC CCAAGTTTGG CATCGAGAAG 
GAGGTGCGCG TGTGTGAGCC CTGCTACGAG CAGCTGAACA GGAAAGCGGA GGGAAAGGCC 
ACTTCCACCA CTGAGCTGCC CCCCGAGTAC CTGACCAGCC CCCTGTCTCA GCAGTCCCAG 
CTGCCCCCCA AGAGGGACGA GACGGCCCTG CAGGAGGAGG AGGAGCTGCA GCTGGCCCTG 
GCGCTGTCAC AGTCAGAGGC GGAGGAGAAG GAGAGGCTGA GACAGAAGTC CACGTACACT 
TCGTACCCCA AGGCGGAGCC CATGCCCTCG GCCTCCTCAG CGCCCCCCGC CAGCAGCCTG 
TACTCTTCAC CTGTGAACTC GTCGGCGCCT CTGGCTGAGG ACATCGACCC TGAGCTCGCA 
CGGTATCTCA ACCGGAACTA CTGGGAGAAG AAGCAGGAGG AGGCTCGCAA GAGCCCCACG 
CCATCTGCGC CCGTGCCCCT GACGGAGCCG GCTGCACAGC CTGGGGAAGG GCACGCAGCC 
CCCACCAACG TGGTGGAGAA CCCCCTCCCG GAGACAGACT CTCAGCCCAT TCCTCCCTCT 
GGTGGCCCCT TTAGTGAGCC ACAGTTCCAC AATGGCGAGT CTGAGGAGAG CCACGAGCAG 
TTCCTGAAGG CGCTGCAGAA CGCCGTCACC ACCTTCGTGA ACCGCATGAA GAGTAACCAC 
ATGCGGGGCC GCAGCATCAC CAATGACTCG GCCGTGCTCT CACTCTTCCA GTCCATCAAC 
GGCATGCACC CGCAGCTGCT GGAGCTGCTC AACCAGCTGG ACGAGCGCAG GCTGTACTAT 
GAGGGGCTGC AGGACAAGCT GGCACAGATC CGCGATGCCC GGGGGGCGCT GAGTGCCCTG 
CGCGAAGAGC ACCGGGAGAA GCTTCGCCGG GCAGCCGAGG AGGCAGAGCG CCAGCGCCAG 
ATCCAGCTGG CCCAGAAGCT GGAGATAATG CGGCAGAAGA AGCAGGAGTA CCTGGAGGTG 
CAGAGGCAGC TGGCCATCCA GCGCCTGCAG GAGCAGGAGA AGGAGCGGCA GATGCGGCTG 
GAGCAGCAGA AGCAGACGGT CCAGATGCGC GCGCAGATGC CCGCCTTCCC CCTGCCCTAC 
GCCCAGCTCC AGGCCATGCC CGCAGCCGGA GGTGTGCTCT ACCAGCCCTC GGGACCAGCC 
AGCTTCCCCA GCACCTTCAG CCCTGCCGGC TCGGTGGAGG GCTCCCCAAT GCACGGCGTG 
TACATGAGCC AGCCGGCCCC TGCCGCTGGC CCCTACCCCA GCATGCCCAG CACTGCGGCT 
GATCCCAGCA TGGTGAGTGC CTACATGTAC CCAGCAGGGG CCACTGGGGC GCAGGCGGCC 
CCCCAGGCCC AGGCCGGACC CACCGCCAGC CCCGCTTACT CATCCTACCA GCCTACTCCC 
ACAGCGGGCT ACCAGAACGT GGCCTCCCAG GCCCCACAGA GCCTCCCGGC CATCTCTCAG 
CCTCCGCAGT CCAGCACCAT GGGCTACATG GGGAGCCAGT CAGTCTCCAT GGGCTACCAG 
CCTTACAACA TGCAGAATCT CATGACCACC CTCCCAAGCC AGGATGCGTC TCTGCCACCC 
CAGCAGCCCT ACATCGCGGG GCAGCAGCCC ATGTACCAGC AGATGGCACC CTCTGGCGGT 
CCCCCCCAGC AGCAGCCCCC CGTGGCCCAG CAACCGCAGG CACAGGGGCC GCCGGCACAG 
GGCAGCGAGG CCCAGCTCAT TTCATTCGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HGS ( XM_024451025.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306793.1 Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu104497
Clone ID Related Accession (Same CDS sequence)	XM_024451024.1 , XM_024451025.1
Accession Version	XM_024451025.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCTG TGGTAAAGAA CTGTGGCCAG ACAGTTCATG ATGAGGTGGC CAACAAGCAG 
ACCATGGAGG AGCTGAAGGA CCTGCTGAAG AGACAAGTGG AGGTAAACGT CCGTAACAAG 
ATCCTGTACC TGATCCAGGC CTGGGCGCAT GCCTTCCGGA ACGAGCCCAA GTACAAGGTG 
GTCCAGGACA CCTACCAGAT CATGAAGGTG GAGGGGCACG TCTTTCCAGA ATTCAAAGAG 
AGCGATGCCA TGTTTGCTGC CGAGAGAGCC CCAGACTGGG TGGACGCTGA GGAATGCCAC 
CGCTGCAGGG TGCAGTTCGG GGTGATGACC CGTAAGCACC ACTGCCGGGC GTGTGGGCAG 
ATATTCTGTG GAAAGTGTTC TTCCAAGTAC TCCACCATCC CCAAGTTTGG CATCGAGAAG 
GAGGTGCGCG TGTGTGAGCC CTGCTACGAG CAGCTGAACA GGAAAGCGGA GGGAAAGGCC 
ACTTCCACCA CTGAGCTGCC CCCCGAGTAC CTGACCAGCC CCCTGTCTCA GCAGTCCCAG 
CTGCCCCCCA AGAGGGACGA GACGGCCCTG CAGGAGGAGG AGGAGCTGCA GCTGGCCCTG 
GCGCTGTCAC AGTCAGAGGC GGAGGAGAAG GAGAGGCTGA GACAGAAGTC CACGTACACT 
TCGTACCCCA AGGCGGAGCC CATGCCCTCG GCCTCCTCAG CGCCCCCCGC CAGCAGCCTG 
TACTCTTCAC CTGTGAACTC GTCGGCGCCT CTGGCTGAGG ACATCGACCC TGAGCTCGCA 
CGGTATCTCA ACCGGAACTA CTGGGAGAAG AAGCAGGAGG AGGCTCGCAA GAGCCCCACG 
CCATCTGCGC CCGTGCCCCT GACGGAGCCG GCTGCACAGC CTGGGGAAGG GCACGCAGCC 
CCCACCAACG TGGTGGAGAA CCCCCTCCCG GAGACAGACT CTCAGCCCAT TCCTCCCTCT 
GGTGGCCCCT TTAGTGAGCC ACAGTTCCAC AATGGCGAGT CTGAGGAGAG CCACGAGCAG 
TTCCTGAAGG CGCTGCAGAA CGCCGTCACC ACCTTCGTGA ACCGCATGAA GAGTAACCAC 
ATGCGGGGCC GCAGCATCAC CAATGACTCG GCCGTGCTCT CACTCTTCCA GTCCATCAAC 
GGCATGCACC CGCAGCTGCT GGAGCTGCTC AACCAGCTGG ACGAGCGCAG GCTGTACTAT 
GAGGGGCTGC AGGACAAGCT GGCACAGATC CGCGATGCCC GGGGGGCGCT GAGTGCCCTG 
CGCGAAGAGC ACCGGGAGAA GCTTCGCCGG GCAGCCGAGG AGGCAGAGCG CCAGCGCCAG 
ATCCAGCTGG CCCAGAAGCT GGAGATAATG CGGCAGAAGA AGCAGGAGTA CCTGGAGGTG 
CAGAGGCAGC TGGCCATCCA GCGCCTGCAG GAGCAGGAGA AGGAGCGGCA GATGCGGCTG 
GAGCAGCAGA AGCAGACGGT CCAGATGCGC GCGCAGATGC CCGCCTTCCC CCTGCCCTAC 
GCCCAGCTCC AGGCCATGCC CGCAGCCGGA GGTGTGCTCT ACCAGCCCTC GGGACCAGCC 
AGCTTCCCCA GCACCTTCAG CCCTGCCGGC TCGGTGGAGG GCTCCCCAAT GCACGGCGTG 
TACATGAGCC AGCCGGCCCC TGCCGCTGGC CCCTACCCCA GCATGCCCAG CACTGCGGCT 
GATCCCAGCA TGGTGAGTGC CTACATGTAC CCAGCAGGGG CCACTGGGGC GCAGGCGGCC 
CCCCAGGCCC AGGCCGGACC CACCGCCAGC CCCGCTTACT CATCCTACCA GCCTACTCCC 
ACAGCGGGCT ACCAGAACGT GGCCTCCCAG GCCCCACAGA GCCTCCCGGC CATCTCTCAG 
CCTCCGCAGT CCAGCACCAT GGGCTACATG GGGAGCCAGT CAGTCTCCAT GGGCTACCAG 
CCTTACAACA TGCAGAATCT CATGACCACC CTCCCAAGCC AGGATGCGTC TCTGCCACCC 
CAGCAGCCCT ACATCGCGGG GCAGCAGCCC ATGTACCAGC AGATGGCACC CTCTGGCGGT 
CCCCCCCAGC AGCAGCCCCC CGTGGCCCAG CAACCGCAGG CACAGGGGCC GCCGGCACAG 
GGCAGCGAGG CCCAGCTCAT TTCATTCGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306793.1
CDS	351..2483
Translation	MESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD

Target ORF information:

RefSeq Version	XM_024451025.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451025.1

ORF Insert Sequence:

ATGGAATCTG TGGTAAAGAA CTGTGGCCAG ACAGTTCATG ATGAGGTGGC CAACAAGCAG 
ACCATGGAGG AGCTGAAGGA CCTGCTGAAG AGACAAGTGG AGGTAAACGT CCGTAACAAG 
ATCCTGTACC TGATCCAGGC CTGGGCGCAT GCCTTCCGGA ACGAGCCCAA GTACAAGGTG 
GTCCAGGACA CCTACCAGAT CATGAAGGTG GAGGGGCACG TCTTTCCAGA ATTCAAAGAG 
AGCGATGCCA TGTTTGCTGC CGAGAGAGCC CCAGACTGGG TGGACGCTGA GGAATGCCAC 
CGCTGCAGGG TGCAGTTCGG GGTGATGACC CGTAAGCACC ACTGCCGGGC GTGTGGGCAG 
ATATTCTGTG GAAAGTGTTC TTCCAAGTAC TCCACCATCC CCAAGTTTGG CATCGAGAAG 
GAGGTGCGCG TGTGTGAGCC CTGCTACGAG CAGCTGAACA GGAAAGCGGA GGGAAAGGCC 
ACTTCCACCA CTGAGCTGCC CCCCGAGTAC CTGACCAGCC CCCTGTCTCA GCAGTCCCAG 
CTGCCCCCCA AGAGGGACGA GACGGCCCTG CAGGAGGAGG AGGAGCTGCA GCTGGCCCTG 
GCGCTGTCAC AGTCAGAGGC GGAGGAGAAG GAGAGGCTGA GACAGAAGTC CACGTACACT 
TCGTACCCCA AGGCGGAGCC CATGCCCTCG GCCTCCTCAG CGCCCCCCGC CAGCAGCCTG 
TACTCTTCAC CTGTGAACTC GTCGGCGCCT CTGGCTGAGG ACATCGACCC TGAGCTCGCA 
CGGTATCTCA ACCGGAACTA CTGGGAGAAG AAGCAGGAGG AGGCTCGCAA GAGCCCCACG 
CCATCTGCGC CCGTGCCCCT GACGGAGCCG GCTGCACAGC CTGGGGAAGG GCACGCAGCC 
CCCACCAACG TGGTGGAGAA CCCCCTCCCG GAGACAGACT CTCAGCCCAT TCCTCCCTCT 
GGTGGCCCCT TTAGTGAGCC ACAGTTCCAC AATGGCGAGT CTGAGGAGAG CCACGAGCAG 
TTCCTGAAGG CGCTGCAGAA CGCCGTCACC ACCTTCGTGA ACCGCATGAA GAGTAACCAC 
ATGCGGGGCC GCAGCATCAC CAATGACTCG GCCGTGCTCT CACTCTTCCA GTCCATCAAC 
GGCATGCACC CGCAGCTGCT GGAGCTGCTC AACCAGCTGG ACGAGCGCAG GCTGTACTAT 
GAGGGGCTGC AGGACAAGCT GGCACAGATC CGCGATGCCC GGGGGGCGCT GAGTGCCCTG 
CGCGAAGAGC ACCGGGAGAA GCTTCGCCGG GCAGCCGAGG AGGCAGAGCG CCAGCGCCAG 
ATCCAGCTGG CCCAGAAGCT GGAGATAATG CGGCAGAAGA AGCAGGAGTA CCTGGAGGTG 
CAGAGGCAGC TGGCCATCCA GCGCCTGCAG GAGCAGGAGA AGGAGCGGCA GATGCGGCTG 
GAGCAGCAGA AGCAGACGGT CCAGATGCGC GCGCAGATGC CCGCCTTCCC CCTGCCCTAC 
GCCCAGCTCC AGGCCATGCC CGCAGCCGGA GGTGTGCTCT ACCAGCCCTC GGGACCAGCC 
AGCTTCCCCA GCACCTTCAG CCCTGCCGGC TCGGTGGAGG GCTCCCCAAT GCACGGCGTG 
TACATGAGCC AGCCGGCCCC TGCCGCTGGC CCCTACCCCA GCATGCCCAG CACTGCGGCT 
GATCCCAGCA TGGTGAGTGC CTACATGTAC CCAGCAGGGG CCACTGGGGC GCAGGCGGCC 
CCCCAGGCCC AGGCCGGACC CACCGCCAGC CCCGCTTACT CATCCTACCA GCCTACTCCC 
ACAGCGGGCT ACCAGAACGT GGCCTCCCAG GCCCCACAGA GCCTCCCGGC CATCTCTCAG 
CCTCCGCAGT CCAGCACCAT GGGCTACATG GGGAGCCAGT CAGTCTCCAT GGGCTACCAG 
CCTTACAACA TGCAGAATCT CATGACCACC CTCCCAAGCC AGGATGCGTC TCTGCCACCC 
CAGCAGCCCT ACATCGCGGG GCAGCAGCCC ATGTACCAGC AGATGGCACC CTCTGGCGGT 
CCCCCCCAGC AGCAGCCCCC CGTGGCCCAG CAACCGCAGG CACAGGGGCC GCCGGCACAG 
GGCAGCGAGG CCCAGCTCAT TTCATTCGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HGS ( XM_017025297.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016880786.1 Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu50793
Clone ID Related Accession (Same CDS sequence)	XM_017025297.1
Accession Version	XM_017025297.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGACAG ACAAGGCGAC CAGCCAGCTC CTGTTGGAGA CAGATTGGGA GTCCATTTTG 
CAGATCTGCG ACCTGATCCG CCAAGGGGAC ACACAAGCAA AATATGCTGT GAATTCCATC 
AAGAAGAAAG TCAACGACAA GAACCCACAC GTCGCCTTGT ATGCCCTGGA GGTCATGGAA 
TCTGTGGTAA AGAACTGTGG CCAGACAGTT CATGATGAGG TGGCCAACAA GCAGACCATG 
GAGGAGCTGA AGGACCTGCT GAAGAGACAA GTGGAGGTAA ACGTCCGTAA CAAGATCCTG 
TACCTGATCC AGGCCTGGGC GCATGCCTTC CGGAACGAGC CCAAGTACAA GGTGGTCCAG 
GACACCTACC AGATCATGAA GGTGGAGGGG CACGTCTTTC CAGAATTCAA AGAGAGCGAT 
GCCATGTTTG CTGCCGAGAG AGCCCCAGAC TGGGTGGACG CTGAGGAATG CCACCGCTGC 
AGGGTGCAGT TCGGGGTGAT GACCCGTAAG CACCACTGCC GGGCGTGTGG GCAGATATTC 
TGTGGAAAGT GTTCTTCCAA GTACTCCACC ATCCCCAAGT TTGGCATCGA GAAGGAGGTG 
CGCGTGTGTG AGCCCTGCTA CGAGCAGCTG AACAGGAAAG CGGAGGGAAA GGCCACTTCC 
ACCACTGAGC TGCCCCCCGA GTACCTGACC AGCCCCCTGT CTCAGCAGTC CCAGCTGCCC 
CCCAAGAGGG ACGAGACGGC CCTGCAGGAG GAGGAGGAGC TGCAGCTGGC CCTGGCGCTG 
TCACAGTCAG AGGCGGAGGA GAAGGAGAGG CTGAGACAGA AGTCCACGTA CACTTCGTAC 
CCCAAGGCGG AGCCCATGCC CTCGGCCTCC TCAGCGCCCC CCGCCAGCAG CCTGTACTCT 
TCACCTGTGA ACTCGTCGGC GCCTCTGGCT GAGGACATCG ACCCTGAGCT CGCACGGTAT 
CTCAACCGGA ACTACTGGGA GAAGAAGCAG GAGGAGGCTC GCAAGAGCCC CACGCCATCT 
GCGCCCGTGC CCCTGACGGA GCCGGCTGCA CAGCCTGGGG AAGGGCACGC AGCCCCCACC 
AACGTGGTGG AGAACCCCCT CCCGGAGACA GACTCTCAGC CCATTCCTCC CTCTGGTGGC 
CCCTTTAGTG AGCCACAGTT CCACAATGGC GAGTCTGAGG AGAGCCACGA GCAGTTCCTG 
AAGGCGCTGC AGAACGCCGT CACCACCTTC GTGAACCGCA TGAAGAGTAA CCACATGCGG 
GGCCGCAGCA TCACCAATGA CTCGGCCGTG CTCTCACTCT TCCAGTCCAT CAACGGCATG 
CACCCGCAGC TGCTGGAGCT GCTCAACCAG CTGGACGAGC GCAGGCTGTA CTATGAGGGG 
CTGCAGGACA AGCTGGCACA GATCCGCGAT GCCCGGGGGG CGCTGAGTGC CCTGCGCGAA 
GAGCACCGGG AGAAGCTTCG CCGGGCAGCC GAGGAGGCAG AGCGCCAGCG CCAGATCCAG 
CTGGCCCAGA AGCTGGAGAT AATGCGGCAG AAGAAGCAGG AGTACCTGGA GGTGCAGAGG 
CAGCTGGCCA TCCAGCGCCT GCAGGAGCAG GAGAAGGAGC GGCAGATGCG GCTGGAGCAG 
CAGAAGCAGA CGGTCCAGAT GCGCGCGCAG ATGCCCGCCT TCCCCCTGCC CTACGCCCAG 
CTCCAGGCCA TGCCCGCAGC CGGAGGTGTG CTCTACCAGC CCTCGGGACC AGCCAGCTTC 
CCCAGCACCT TCAGCCCTGC CGGCTCGGTG GAGGGCTCCC CAATGCACGG CGTGTACATG 
AGCCAGCCGG CCCCTGCCGC TGGCCCCTAC CCCAGCATGC CCAGCACTGC GGCTGATCCC 
AGCATGGTGA GTGCCTACAT GTACCCAGCA GGGGCCACTG GGGCGCAGGC GGCCCCCCAG 
GCCCAGGCCG GACCCACCGC CAGCCCCGCT TACTCATCCT ACCAGCCTAC TCCCACAGCG 
GGCTACCAGA ACGTGGCCTC CCAGGCCCCA CAGAGCCTCC CGGCCATCTC TCAGCCTCCG 
CAGTCCAGCA CCATGGGCTA CATGGGGAGC CAGTCAGTCT CCATGGGCTA CCAGCCTTAC 
AACATGCAGA ATCTCATGAC CACCCTCCCA AGCCAGGATG CGTCTCTGCC ACCCCAGCAG 
CCCTACATCG CGGGGCAGCA GCCCATGTAC CAGCAGATGG CACCCTCTGG CGGTCCCCCC 
CAGCAGCAGC CCCCCGTGGC CCAGCAACCG CAGGCACAGG GGCCGCCGGC ACAGGGCAGC 
GAGGCCCAGC TCATTTCATT CGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016880786.1
CDS	320..2626
Translation	MMTDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD

Target ORF information:

RefSeq Version	XM_017025297.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017025297.1

ORF Insert Sequence:

ATGATGACAG ACAAGGCGAC CAGCCAGCTC CTGTTGGAGA CAGATTGGGA GTCCATTTTG 
CAGATCTGCG ACCTGATCCG CCAAGGGGAC ACACAAGCAA AATATGCTGT GAATTCCATC 
AAGAAGAAAG TCAACGACAA GAACCCACAC GTCGCCTTGT ATGCCCTGGA GGTCATGGAA 
TCTGTGGTAA AGAACTGTGG CCAGACAGTT CATGATGAGG TGGCCAACAA GCAGACCATG 
GAGGAGCTGA AGGACCTGCT GAAGAGACAA GTGGAGGTAA ACGTCCGTAA CAAGATCCTG 
TACCTGATCC AGGCCTGGGC GCATGCCTTC CGGAACGAGC CCAAGTACAA GGTGGTCCAG 
GACACCTACC AGATCATGAA GGTGGAGGGG CACGTCTTTC CAGAATTCAA AGAGAGCGAT 
GCCATGTTTG CTGCCGAGAG AGCCCCAGAC TGGGTGGACG CTGAGGAATG CCACCGCTGC 
AGGGTGCAGT TCGGGGTGAT GACCCGTAAG CACCACTGCC GGGCGTGTGG GCAGATATTC 
TGTGGAAAGT GTTCTTCCAA GTACTCCACC ATCCCCAAGT TTGGCATCGA GAAGGAGGTG 
CGCGTGTGTG AGCCCTGCTA CGAGCAGCTG AACAGGAAAG CGGAGGGAAA GGCCACTTCC 
ACCACTGAGC TGCCCCCCGA GTACCTGACC AGCCCCCTGT CTCAGCAGTC CCAGCTGCCC 
CCCAAGAGGG ACGAGACGGC CCTGCAGGAG GAGGAGGAGC TGCAGCTGGC CCTGGCGCTG 
TCACAGTCAG AGGCGGAGGA GAAGGAGAGG CTGAGACAGA AGTCCACGTA CACTTCGTAC 
CCCAAGGCGG AGCCCATGCC CTCGGCCTCC TCAGCGCCCC CCGCCAGCAG CCTGTACTCT 
TCACCTGTGA ACTCGTCGGC GCCTCTGGCT GAGGACATCG ACCCTGAGCT CGCACGGTAT 
CTCAACCGGA ACTACTGGGA GAAGAAGCAG GAGGAGGCTC GCAAGAGCCC CACGCCATCT 
GCGCCCGTGC CCCTGACGGA GCCGGCTGCA CAGCCTGGGG AAGGGCACGC AGCCCCCACC 
AACGTGGTGG AGAACCCCCT CCCGGAGACA GACTCTCAGC CCATTCCTCC CTCTGGTGGC 
CCCTTTAGTG AGCCACAGTT CCACAATGGC GAGTCTGAGG AGAGCCACGA GCAGTTCCTG 
AAGGCGCTGC AGAACGCCGT CACCACCTTC GTGAACCGCA TGAAGAGTAA CCACATGCGG 
GGCCGCAGCA TCACCAATGA CTCGGCCGTG CTCTCACTCT TCCAGTCCAT CAACGGCATG 
CACCCGCAGC TGCTGGAGCT GCTCAACCAG CTGGACGAGC GCAGGCTGTA CTATGAGGGG 
CTGCAGGACA AGCTGGCACA GATCCGCGAT GCCCGGGGGG CGCTGAGTGC CCTGCGCGAA 
GAGCACCGGG AGAAGCTTCG CCGGGCAGCC GAGGAGGCAG AGCGCCAGCG CCAGATCCAG 
CTGGCCCAGA AGCTGGAGAT AATGCGGCAG AAGAAGCAGG AGTACCTGGA GGTGCAGAGG 
CAGCTGGCCA TCCAGCGCCT GCAGGAGCAG GAGAAGGAGC GGCAGATGCG GCTGGAGCAG 
CAGAAGCAGA CGGTCCAGAT GCGCGCGCAG ATGCCCGCCT TCCCCCTGCC CTACGCCCAG 
CTCCAGGCCA TGCCCGCAGC CGGAGGTGTG CTCTACCAGC CCTCGGGACC AGCCAGCTTC 
CCCAGCACCT TCAGCCCTGC CGGCTCGGTG GAGGGCTCCC CAATGCACGG CGTGTACATG 
AGCCAGCCGG CCCCTGCCGC TGGCCCCTAC CCCAGCATGC CCAGCACTGC GGCTGATCCC 
AGCATGGTGA GTGCCTACAT GTACCCAGCA GGGGCCACTG GGGCGCAGGC GGCCCCCCAG 
GCCCAGGCCG GACCCACCGC CAGCCCCGCT TACTCATCCT ACCAGCCTAC TCCCACAGCG 
GGCTACCAGA ACGTGGCCTC CCAGGCCCCA CAGAGCCTCC CGGCCATCTC TCAGCCTCCG 
CAGTCCAGCA CCATGGGCTA CATGGGGAGC CAGTCAGTCT CCATGGGCTA CCAGCCTTAC 
AACATGCAGA ATCTCATGAC CACCCTCCCA AGCCAGGATG CGTCTCTGCC ACCCCAGCAG 
CCCTACATCG CGGGGCAGCA GCCCATGTAC CAGCAGATGG CACCCTCTGG CGGTCCCCCC 
CAGCAGCAGC CCCCCGTGGC CCAGCAACCG CAGGCACAGG GGCCGCCGGC ACAGGGCAGC 
GAGGCCCAGC TCATTTCATT CGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HGS ( XM_011525463.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011523765.1 Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu62516
Clone ID Related Accession (Same CDS sequence)	XM_011525463.2
Accession Version	XM_011525463.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011525463.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AGGCGACCAG CCAGCTCCTG 
TTGGAGACAG ATTGGGAGTC CATTTTGCAG ATCTGCGACC TGATCCGCCA AGGGGACACA 
CAAGCAAAAT ATGCTGTGAA TTCCATCAAG AAGAAAGTCA ACGACAAGAA CCCACACGTC 
GCCTTGTATG CCCTGGAGGT CATGGAATCT GTGGTAAAGA ACTGTGGCCA GACAGTTCAT 
GATGAGGTGG CCAACAAGCA GACCATGGAG GAGCTGAAGG ACCTGCTGAA GAGACAAGTG 
GAGGTAAACG TCCGTAACAA GATCCTGTAC CTGATCCAGG CCTGGGCGCA TGCCTTCCGG 
AACGAGCCCA AGTACAAGGT GGTCCAGGAC ACCTACCAGA TCATGAAGGT GGAGGGGCAC 
GTCTTTCCAG AATTCAAAGA GAGCGATGCC ATGTTTGCTG CCGAGAGAGC CCCAGACTGG 
GTGGACGCTG AGGAATGCCA CCGCTGCAGG GTGCAGTTCG GGGTGATGAC CCGTAAGCAC 
CACTGCCGGG CGTGTGGGCA GATATTCTGT GGAAAGTGTT CTTCCAAGTA CTCCACCATC 
CCCAAGTTTG GCATCGAGAA GGAGGTGCGC GTGTGTGAGC CCTGCTACGA GCAGCTGAAC 
AGGAAAGCGG AGGGAAAGGC CACTTCCACC ACTGAGCTGC CCCCCGAGTA CCTGACCAGC 
CCCCTGTCTC AGCAGTCCCA GCTGCCCCCC AAGAGGGACG AGACGGCCCT GCAGGAGGAG 
GAGGAGCTGC AGCTGGCCCT GGCGCTGTCA CAGTCAGAGG CGGAGGAGAA GGAGAGGCTG 
AGACAGAAGT CCACGTACAC TTCGTACCCC AAGGCGGAGC CCATGCCCTC GGCCTCCTCA 
GCGCCCCCCG CCAGCAGCCT GTACTCTTCA CCTGTGAACT CGTCGGCGCC TCTGGCTGAG 
GACATCGACC CTGAGCTCGC ACGGTATCTC AACCGGAACT ACTGGGAGAA GAAGCAGGAG 
GAGGCTCGCA AGAGCCCCAC GCCATCTGCG CCCGTGCCCC TGACGGAGCC GGCTGCACAG 
CCTGGGGAAG GGCACGCAGC CCCCACCAAC GTGGTGGAGA ACCCCCTCCC GGAGACAGAC 
TCTCAGCCCA TTCCTCCCTC TGGTGGCCCC TTTAGTGAGC CACAGTTCCA CAATGGCGAG 
TCTGAGGAGA GCCACGAGCA GTTCCTGAAG GCGCTGCAGA ACGCCGTCAC CACCTTCGTG 
AACCGCATGA AGAGTAACCA CATGCGGGGC CGCAGCATCA CCAATGACTC GGCCGTGCTC 
TCACTCTTCC AGTCCATCAA CGGCATGCAC CCGCAGCTGC TGGAGCTGCT CAACCAGCTG 
GACGAGCGCA GGCTGTACTA TGAGGGGCTG CAGGACAAGC TGGCACAGAT CCGCGATGCC 
CGGGGGGCGC TGAGTGCCCT GCGCGAAGAG CACCGGGAGA AGCTTCGCCG GGCAGCCGAG 
GAGGCAGAGC GCCAGCGCCA GATCCAGCTG GCCCAGAAGC TGGAGATAAT GCGGCAGAAG 
AAGCAGGAGT ACCTGGAGGT GCAGAGGCAG CTGGCCATCC AGCGCCTGCA GGAGCAGGAG 
AAGGAGCGGC AGATGCGGCT GGAGCAGCAG AAGCAGACGG TCCAGATGCG CGCGCAGATG 
CCCGCCTTCC CCCTGCCCTA CGCCCAGCTC CAGGCCATGC CCGCAGCCGG AGGTGTGCTC 
TACCAGCCCT CGGGACCAGC CAGCTTCCCC AGCACCTTCA GCCCTGCCGG CTCGGTGGAG 
GGCTCCCCAA TGCACGGCGT GTACATGAGC CAGCCGGCCC CTGCCGCTGG CCCCTACCCC 
AGCATGCCCA GCACTGCGGC TGATCCCAGC ATGGTGAGTG CCTACATGTA CCCAGCAGGG 
GCCACTGGGG CGCAGGCGGC CCCCCAGGCC CAGGCCGGAC CCACCGCCAG CCCCGCTTAC 
TCATCCTACC AGCCTACTCC CACAGCGGGC TACCAGAACG TGGCCTCCCA GGCCCCACAG 
AGCCTCCCGG CCATCTCTCA GCCTCCGCAG TCCAGCACCA TGGGCTACAT GGGGAGCCAG 
TCAGTCTCCA TGGGCTACCA GCCTTACAAC ATGCAGAATC TCATGACCAC CCTCCCAAGC 
CAGGATGCGT CTCTGCCACC CCAGCAGCCC TACATCGCGG GGCAGCAGCC CATGTACCAG 
CAGGGGGAGA CGCATACCCG AGGCCCCTTC TCAGCAGACA GAACGAGGAC ACAAGTCTCA 
GGGCAGATAC GCGCATCCGC AAGTGTAGAC AGGAAAAACC GTGAATTTAC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011523765.1
CDS	85..2418
Translation	MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQGETHTRGPFSADRTRTQVSGQIRASASVDRKNREFT

Target ORF information:

RefSeq Version	XM_011525463.2
Organism	Homo sapiens(human)
Definition	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011525463.2

ORF Insert Sequence:

ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGACA AGGCGACCAG CCAGCTCCTG 
TTGGAGACAG ATTGGGAGTC CATTTTGCAG ATCTGCGACC TGATCCGCCA AGGGGACACA 
CAAGCAAAAT ATGCTGTGAA TTCCATCAAG AAGAAAGTCA ACGACAAGAA CCCACACGTC 
GCCTTGTATG CCCTGGAGGT CATGGAATCT GTGGTAAAGA ACTGTGGCCA GACAGTTCAT 
GATGAGGTGG CCAACAAGCA GACCATGGAG GAGCTGAAGG ACCTGCTGAA GAGACAAGTG 
GAGGTAAACG TCCGTAACAA GATCCTGTAC CTGATCCAGG CCTGGGCGCA TGCCTTCCGG 
AACGAGCCCA AGTACAAGGT GGTCCAGGAC ACCTACCAGA TCATGAAGGT GGAGGGGCAC 
GTCTTTCCAG AATTCAAAGA GAGCGATGCC ATGTTTGCTG CCGAGAGAGC CCCAGACTGG 
GTGGACGCTG AGGAATGCCA CCGCTGCAGG GTGCAGTTCG GGGTGATGAC CCGTAAGCAC 
CACTGCCGGG CGTGTGGGCA GATATTCTGT GGAAAGTGTT CTTCCAAGTA CTCCACCATC 
CCCAAGTTTG GCATCGAGAA GGAGGTGCGC GTGTGTGAGC CCTGCTACGA GCAGCTGAAC 
AGGAAAGCGG AGGGAAAGGC CACTTCCACC ACTGAGCTGC CCCCCGAGTA CCTGACCAGC 
CCCCTGTCTC AGCAGTCCCA GCTGCCCCCC AAGAGGGACG AGACGGCCCT GCAGGAGGAG 
GAGGAGCTGC AGCTGGCCCT GGCGCTGTCA CAGTCAGAGG CGGAGGAGAA GGAGAGGCTG 
AGACAGAAGT CCACGTACAC TTCGTACCCC AAGGCGGAGC CCATGCCCTC GGCCTCCTCA 
GCGCCCCCCG CCAGCAGCCT GTACTCTTCA CCTGTGAACT CGTCGGCGCC TCTGGCTGAG 
GACATCGACC CTGAGCTCGC ACGGTATCTC AACCGGAACT ACTGGGAGAA GAAGCAGGAG 
GAGGCTCGCA AGAGCCCCAC GCCATCTGCG CCCGTGCCCC TGACGGAGCC GGCTGCACAG 
CCTGGGGAAG GGCACGCAGC CCCCACCAAC GTGGTGGAGA ACCCCCTCCC GGAGACAGAC 
TCTCAGCCCA TTCCTCCCTC TGGTGGCCCC TTTAGTGAGC CACAGTTCCA CAATGGCGAG 
TCTGAGGAGA GCCACGAGCA GTTCCTGAAG GCGCTGCAGA ACGCCGTCAC CACCTTCGTG 
AACCGCATGA AGAGTAACCA CATGCGGGGC CGCAGCATCA CCAATGACTC GGCCGTGCTC 
TCACTCTTCC AGTCCATCAA CGGCATGCAC CCGCAGCTGC TGGAGCTGCT CAACCAGCTG 
GACGAGCGCA GGCTGTACTA TGAGGGGCTG CAGGACAAGC TGGCACAGAT CCGCGATGCC 
CGGGGGGCGC TGAGTGCCCT GCGCGAAGAG CACCGGGAGA AGCTTCGCCG GGCAGCCGAG 
GAGGCAGAGC GCCAGCGCCA GATCCAGCTG GCCCAGAAGC TGGAGATAAT GCGGCAGAAG 
AAGCAGGAGT ACCTGGAGGT GCAGAGGCAG CTGGCCATCC AGCGCCTGCA GGAGCAGGAG 
AAGGAGCGGC AGATGCGGCT GGAGCAGCAG AAGCAGACGG TCCAGATGCG CGCGCAGATG 
CCCGCCTTCC CCCTGCCCTA CGCCCAGCTC CAGGCCATGC CCGCAGCCGG AGGTGTGCTC 
TACCAGCCCT CGGGACCAGC CAGCTTCCCC AGCACCTTCA GCCCTGCCGG CTCGGTGGAG 
GGCTCCCCAA TGCACGGCGT GTACATGAGC CAGCCGGCCC CTGCCGCTGG CCCCTACCCC 
AGCATGCCCA GCACTGCGGC TGATCCCAGC ATGGTGAGTG CCTACATGTA CCCAGCAGGG 
GCCACTGGGG CGCAGGCGGC CCCCCAGGCC CAGGCCGGAC CCACCGCCAG CCCCGCTTAC 
TCATCCTACC AGCCTACTCC CACAGCGGGC TACCAGAACG TGGCCTCCCA GGCCCCACAG 
AGCCTCCCGG CCATCTCTCA GCCTCCGCAG TCCAGCACCA TGGGCTACAT GGGGAGCCAG 
TCAGTCTCCA TGGGCTACCA GCCTTACAAC ATGCAGAATC TCATGACCAC CCTCCCAAGC 
CAGGATGCGT CTCTGCCACC CCAGCAGCCC TACATCGCGG GGCAGCAGCC CATGTACCAG 
CAGGGGGAGA CGCATACCCG AGGCCCCTTC TCAGCAGACA GAACGAGGAC ACAAGTCTCA 
GGGCAGATAC GCGCATCCGC AAGTGTAGAC AGGAAAAACC GTGAATTTAC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HGS ( XM_017025298.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016880787.1 Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu62517
Clone ID Related Accession (Same CDS sequence)	XM_017025298.1
Accession Version	XM_017025298.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1809bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	hepatocyte growth factor-regulated tyrosine kinase substrate isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCGTA AGCACCACTG CCGGGCGTGT GGGCAGATAT TCTGTGGAAA GTGTTCTTCC 
AAGTACTCCA CCATCCCCAA GTTTGGCATC GAGAAGGAGG TGCGCGTGTG TGAGCCCTGC 
TACGAGCAGC TGAACAGGAA AGCGGAGGGA AAGGCCACTT CCACCACTGA GCTGCCCCCC 
GAGTACCTGA CCAGCCCCCT GTCTCAGCAG TCCCAGCTGC CCCCCAAGAG GGACGAGACG 
GCCCTGCAGG AGGAGGAGGA GCTGCAGCTG GCCCTGGCGC TGTCACAGTC AGAGGCGGAG 
GAGAAGGAGA GGCTGAGACA GAAGTCCACG TACACTTCGT ACCCCAAGGC GGAGCCCATG 
CCCTCGGCCT CCTCAGCGCC CCCCGCCAGC AGCCTGTACT CTTCACCTGT GAACTCGTCG 
GCGCCTCTGG CTGAGGACAT CGACCCTGAG CTCGCACGGT ATCTCAACCG GAACTACTGG 
GAGAAGAAGC AGGAGGAGGC TCGCAAGAGC CCCACGCCAT CTGCGCCCGT GCCCCTGACG 
GAGCCGGCTG CACAGCCTGG GGAAGGGCAC GCAGCCCCCA CCAACGTGGT GGAGAACCCC 
CTCCCGGAGA CAGACTCTCA GCCCATTCCT CCCTCTGGTG GCCCCTTTAG TGAGCCACAG 
TTCCACAATG GCGAGTCTGA GGAGAGCCAC GAGCAGTTCC TGAAGGCGCT GCAGAACGCC 
GTCACCACCT TCGTGAACCG CATGAAGAGT AACCACATGC GGGGCCGCAG CATCACCAAT 
GACTCGGCCG TGCTCTCACT CTTCCAGTCC ATCAACGGCA TGCACCCGCA GCTGCTGGAG 
CTGCTCAACC AGCTGGACGA GCGCAGGCTG TACTATGAGG GGCTGCAGGA CAAGCTGGCA 
CAGATCCGCG ATGCCCGGGG GGCGCTGAGT GCCCTGCGCG AAGAGCACCG GGAGAAGCTT 
CGCCGGGCAG CCGAGGAGGC AGAGCGCCAG CGCCAGATCC AGCTGGCCCA GAAGCTGGAG 
ATAATGCGGC AGAAGAAGCA GGAGTACCTG GAGGTGCAGA GGCAGCTGGC CATCCAGCGC 
CTGCAGGAGC AGGAGAAGGA GCGGCAGATG CGGCTGGAGC AGCAGAAGCA GACGGTCCAG 
ATGCGCGCGC AGATGCCCGC CTTCCCCCTG CCCTACGCCC AGCTCCAGGC CATGCCCGCA 
GCCGGAGGTG TGCTCTACCA GCCCTCGGGA CCAGCCAGCT TCCCCAGCAC CTTCAGCCCT 
GCCGGCTCGG TGGAGGGCTC CCCAATGCAC GGCGTGTACA TGAGCCAGCC GGCCCCTGCC 
GCTGGCCCCT ACCCCAGCAT GCCCAGCACT GCGGCTGATC CCAGCATGGT GAGTGCCTAC 
ATGTACCCAG CAGGGGCCAC TGGGGCGCAG GCGGCCCCCC AGGCCCAGGC CGGACCCACC 
GCCAGCCCCG CTTACTCATC CTACCAGCCT ACTCCCACAG CGGGCTACCA GAACGTGGCC 
TCCCAGGCCC CACAGAGCCT CCCGGCCATC TCTCAGCCTC CGCAGTCCAG CACCATGGGC 
TACATGGGGA GCCAGTCAGT CTCCATGGGC TACCAGCCTT ACAACATGCA GAATCTCATG 
ACCACCCTCC CAAGCCAGGA TGCGTCTCTG CCACCCCAGC AGCCCTACAT CGCGGGGCAG 
CAGCCCATGT ACCAGCAGAT GGCACCCTCT GGCGGTCCCC CCCAGCAGCA GCCCCCCGTG 
GCCCAGCAAC CGCAGGCACA GGGGCCGCCG GCACAGGGCA GCGAGGCCCA GCTCATTTCA 
TTCGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016880787.1
CDS	541..2349
Translation	MTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD

Target ORF information:

RefSeq Version	XM_017025298.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017025298.1

ORF Insert Sequence:

ATGACCCGTA AGCACCACTG CCGGGCGTGT GGGCAGATAT TCTGTGGAAA GTGTTCTTCC 
AAGTACTCCA CCATCCCCAA GTTTGGCATC GAGAAGGAGG TGCGCGTGTG TGAGCCCTGC 
TACGAGCAGC TGAACAGGAA AGCGGAGGGA AAGGCCACTT CCACCACTGA GCTGCCCCCC 
GAGTACCTGA CCAGCCCCCT GTCTCAGCAG TCCCAGCTGC CCCCCAAGAG GGACGAGACG 
GCCCTGCAGG AGGAGGAGGA GCTGCAGCTG GCCCTGGCGC TGTCACAGTC AGAGGCGGAG 
GAGAAGGAGA GGCTGAGACA GAAGTCCACG TACACTTCGT ACCCCAAGGC GGAGCCCATG 
CCCTCGGCCT CCTCAGCGCC CCCCGCCAGC AGCCTGTACT CTTCACCTGT GAACTCGTCG 
GCGCCTCTGG CTGAGGACAT CGACCCTGAG CTCGCACGGT ATCTCAACCG GAACTACTGG 
GAGAAGAAGC AGGAGGAGGC TCGCAAGAGC CCCACGCCAT CTGCGCCCGT GCCCCTGACG 
GAGCCGGCTG CACAGCCTGG GGAAGGGCAC GCAGCCCCCA CCAACGTGGT GGAGAACCCC 
CTCCCGGAGA CAGACTCTCA GCCCATTCCT CCCTCTGGTG GCCCCTTTAG TGAGCCACAG 
TTCCACAATG GCGAGTCTGA GGAGAGCCAC GAGCAGTTCC TGAAGGCGCT GCAGAACGCC 
GTCACCACCT TCGTGAACCG CATGAAGAGT AACCACATGC GGGGCCGCAG CATCACCAAT 
GACTCGGCCG TGCTCTCACT CTTCCAGTCC ATCAACGGCA TGCACCCGCA GCTGCTGGAG 
CTGCTCAACC AGCTGGACGA GCGCAGGCTG TACTATGAGG GGCTGCAGGA CAAGCTGGCA 
CAGATCCGCG ATGCCCGGGG GGCGCTGAGT GCCCTGCGCG AAGAGCACCG GGAGAAGCTT 
CGCCGGGCAG CCGAGGAGGC AGAGCGCCAG CGCCAGATCC AGCTGGCCCA GAAGCTGGAG 
ATAATGCGGC AGAAGAAGCA GGAGTACCTG GAGGTGCAGA GGCAGCTGGC CATCCAGCGC 
CTGCAGGAGC AGGAGAAGGA GCGGCAGATG CGGCTGGAGC AGCAGAAGCA GACGGTCCAG 
ATGCGCGCGC AGATGCCCGC CTTCCCCCTG CCCTACGCCC AGCTCCAGGC CATGCCCGCA 
GCCGGAGGTG TGCTCTACCA GCCCTCGGGA CCAGCCAGCT TCCCCAGCAC CTTCAGCCCT 
GCCGGCTCGG TGGAGGGCTC CCCAATGCAC GGCGTGTACA TGAGCCAGCC GGCCCCTGCC 
GCTGGCCCCT ACCCCAGCAT GCCCAGCACT GCGGCTGATC CCAGCATGGT GAGTGCCTAC 
ATGTACCCAG CAGGGGCCAC TGGGGCGCAG GCGGCCCCCC AGGCCCAGGC CGGACCCACC 
GCCAGCCCCG CTTACTCATC CTACCAGCCT ACTCCCACAG CGGGCTACCA GAACGTGGCC 
TCCCAGGCCC CACAGAGCCT CCCGGCCATC TCTCAGCCTC CGCAGTCCAG CACCATGGGC 
TACATGGGGA GCCAGTCAGT CTCCATGGGC TACCAGCCTT ACAACATGCA GAATCTCATG 
ACCACCCTCC CAAGCCAGGA TGCGTCTCTG CCACCCCAGC AGCCCTACAT CGCGGGGCAG 
CAGCCCATGT ACCAGCAGAT GGCACCCTCT GGCGGTCCCC CCCAGCAGCA GCCCCCCGTG 
GCCCAGCAAC CGCAGGCACA GGGGCCGCCG GCACAGGGCA GCGAGGCCCA GCTCATTTCA 
TTCGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor.
Scientific reports7(1)12389(2017 Sep)
Roux BT,Bauer CC,McNeish AJ,Ward SG,Cottrell GS

ESCRT-0 Component Hrs Promotes Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus in Human Dermal Microvascular Endothelial Cells.
Journal of virology90(8)3860-72(2016 Apr)
Veettil MV,Kumar B,Ansari MA,Dutta D,Iqbal J,Gjyshi O,Bottero V,Chandran B

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

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HGS cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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