Gene Symbol | ARHGEF1 |
Entrez Gene ID | 9138 |
Full Name | Rho guanine nucleotide exchange factor 1 |
Synonyms | GEF1,LBCL2,LSC,P115-RHOGEF,SUB1.5 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |