ATP6V0D1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATP6V0D1
Entrez Gene ID	9114
Full Name	ATPase H+ transporting V0 subunit d1
Synonyms	ATP6D,ATP6DV,P39,VATX,VMA6,VPATPD
General protein information	Preferred Names ATPase H+ transporting V0 subunit d1 Names V-type proton ATPase subunit d 1 32 kDa accessory protein ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 H(+)-transporting two-sector ATPase, subunit D V-ATPase 40 KDa accessory protein V-ATPase AC39 subunit V-ATPase subunit d 1 V-ATPase, subunit D vacuolar proton pump subunit d 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q22.1
Summary	This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008].
Disorder MIM:	607028

mRNA and Protein(s)

mRNA	Protein	Name
NM_004691.5	NP_004682.2	V-type proton ATPase subunit d 1
XM_011523445.1	XP_011521747.1	V-type proton ATPase subunit d 1 isoform X1
XM_011523446.1	XP_011521748.1	V-type proton ATPase subunit d 1 isoform X1
XM_011523444.1	XP_011521746.1	V-type proton ATPase subunit d 1 isoform X1
NM_004691.4	NP_004682.2	V-type proton ATPase subunit d 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Atp6v0d1	NP_038505.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000721	XP_311260.4
Saccharomyces cerevisiae (baker's yeast)	VMA6	NP_013552.3
Xenopus tropicalis (tropical clawed frog)	atp6v0d1	NP_001017310.1
Homo sapiens (human)	ATP6V0D1	NP_004682.2
Arabidopsis thaliana (thale cress)	AT3G28710	NP_189512.1
Arabidopsis thaliana (thale cress)	AT3G28715	NP_189513.1
Pan troglodytes (chimpanzee)	ATP6V0D1	XP_001163837.1
Canis lupus familiaris (dog)	ATP6V0D1	XP_536816.2
Bos taurus (cattle)	ATP6V0D1	NP_776930.1
Gallus gallus (chicken)	ATP6V0D1	XP_414041.1
Caenorhabditis elegans (roundworm)	vha-16	NP_491515.2
Kluyveromyces lactis	KLLA0B04752g	XP_451745.1
Eremothecium gossypii	AGOS_AER146C	NP_985005.2
Magnaporthe oryzae (rice blast fungus)	MGG_07007	XP_003709765.1
Neurospora crassa	NCU03395	XP_956842.1
Rattus norvegicus (Norway rat)	Atp6v0d1	NP_001011927.1
Danio rerio (zebrafish)	atp6v0d1	NP_955914.1
Drosophila melanogaster (fruit fly)	VhaAC39-1	NP_570080.1
Schizosaccharomyces pombe (fission yeast)	vma6	NP_594237.1
Oryza sativa (rice)	Os01g0587000	NP_001043429.1

Gene Ontology
Bibliography

Related articles in PubMed

The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels.
Miles AL, Burr SP, Grice GL, Nathan JA
eLife6(2017 03)

Expression, purification and characterization of human vacuolar-type H(+)-ATPase subunit d1 and d2 in Escherichia coli.
Lim H, Cheong HK, Rho JR, Hyun JK, Kim YJ
Protein expression and purification9825-31(2014 Jun)

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.
H?hn A, Sittig A, Jung T, Grimm S, Grune T
Free radical biology & medicine53(9)1760-9(2012 Nov)

A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo.
Chen Y, Wu B, Xu L, Li H, Xia J, Yin W, Li Z, Shi D, Li S, Lin S, Shu X, Pei D
Cell research22(2)333-45(2012 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The secondary structures of d1 and d2 subunits were highly similar, but the relative stability against thermal stress was higher for d1 than d2.
Title: Expression, purification and characterization of human vacuolar-type H(+)-ATPase subunit d1 and d2 in Escherichia coli.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

two adjacent enhancers inside the first intron of the neighboring (1.4 kb downstream) ATPase gene (ATP6V0D1) modulate the human AgRP promoter with profound spatiotemporal variation
Title: Control elements in the neighboring ATPase gene influence spatiotemporal expression of the human agouti-related protein.

Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia
Title: Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.

The following ATP6V0D1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP6V0D1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18928	NM_004691.5 Latest version!	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu62487	XM_011523446.1 Latest version!	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu62487	XM_011523444.1 Latest version!	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu62487	XM_011523445.1 Latest version!	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
View Old Accession Versions >>
OHu18928	NM_004691.4	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATP6V0D1 ( NM_004691.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_004682.2 Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), mRNA.

Price & Availability↑

CloneID	OHu18928
Clone ID Related Accession (Same CDS sequence)	NM_004691.5 , NM_004691.4
Accession Version	NM_004691.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit d 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC008861.2 and BM677562.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_004691.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.175846.1, SRR3476690.332825.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000290949.8/ ENSP00000290949.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGTTCT TCCCGGAGCT TTACTTTAAC GTGGACAATG GCTACTTGGA GGGACTGGTG 
CGCGGCCTGA AGGCCGGGGT GCTCAGCCAG GCCGACTACC TCAACCTGGT GCAGTGCGAG 
ACGCTAGAGG ACTTGAAACT GCATCTGCAG AGCACTGATT ATGGTAACTT CCTGGCCAAC 
GAGGCATCAC CTCTGACGGT GTCAGTCATC GATGACCGGC TCAAGGAGAA GATGGTGGTG 
GAGTTCCGCC ACATGAGGAA CCATGCCTAT GAGCCACTCG CCAGCTTCCT AGACTTCATT 
ACTTACAGTT ACATGATCGA CAACGTGATC CTGCTCATCA CAGGCACGCT GCACCAGCGC 
TCCATCGCTG AGCTCGTGCC CAAGTGCCAC CCACTAGGCA GCTTCGAGCA GATGGAGGCC 
GTGAACATTG CTCAGACACC TGCTGAGCTC TACAATGCCA TTCTGGTGGA CACGCCTCTT 
GCGGCTTTTT TCCAGGACTG CATTTCAGAG CAGGACCTTG ACGAGATGAA CATCGAGATC 
ATCCGCAACA CCCTCTACAA GGCCTACCTG GAGTCCTTCT ACAAGTTCTG CACCCTACTG 
GGCGGGACTA CGGCTGATGC CATGTGCCCC ATCCTGGAGT TTGAAGCAGA CCGCCGCGCC 
TTCATCATCA CCATCAATTC TTTCGGCACA GAGCTGTCCA AAGAGGACCG TGCCAAGCTC 
TTTCCACACT GTGGGCGGCT CTACCCTGAG GGCCTGGCGC AGCTGGCTCG GGCTGACGAC 
TATGAACAGG TCAAGAACGT GGCCGATTAC TACCCGGAGT ACAAGCTGCT CTTCGAGGGT 
GCAGGTAGCA ACCCTGGAGA CAAGACGCTG GAGGACCGAT TCTTTGAGCA CGAGGTAAAG 
CTGAACAAGT TGGCCTTCCT GAACCAGTTC CACTTTGGTG TCTTCTATGC CTTCGTGAAG 
CTCAAGGAGC AGGAGTGTCG CAACATCGTG TGGATCGCTG AATGTATCGC CCAGCGCCAC 
CGCGCCAAAA TCGACAACTA CATCCCTATC TTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004682.2
CDS	72..1127
Translation	MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLTVSVIDDRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF

Target ORF information:

RefSeq Version	NM_004691.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004691.5

ORF Insert Sequence:

ATGTCGTTCT TCCCGGAGCT TTACTTTAAC GTGGACAATG GCTACTTGGA GGGACTGGTG 
CGCGGCCTGA AGGCCGGGGT GCTCAGCCAG GCCGACTACC TCAACCTGGT GCAGTGCGAG 
ACGCTAGAGG ACTTGAAACT GCATCTGCAG AGCACTGATT ATGGTAACTT CCTGGCCAAC 
GAGGCATCAC CTCTGACGGT GTCAGTCATC GATGACCGGC TCAAGGAGAA GATGGTGGTG 
GAGTTCCGCC ACATGAGGAA CCATGCCTAT GAGCCACTCG CCAGCTTCCT AGACTTCATT 
ACTTACAGTT ACATGATCGA CAACGTGATC CTGCTCATCA CAGGCACGCT GCACCAGCGC 
TCCATCGCTG AGCTCGTGCC CAAGTGCCAC CCACTAGGCA GCTTCGAGCA GATGGAGGCC 
GTGAACATTG CTCAGACACC TGCTGAGCTC TACAATGCCA TTCTGGTGGA CACGCCTCTT 
GCGGCTTTTT TCCAGGACTG CATTTCAGAG CAGGACCTTG ACGAGATGAA CATCGAGATC 
ATCCGCAACA CCCTCTACAA GGCCTACCTG GAGTCCTTCT ACAAGTTCTG CACCCTACTG 
GGCGGGACTA CGGCTGATGC CATGTGCCCC ATCCTGGAGT TTGAAGCAGA CCGCCGCGCC 
TTCATCATCA CCATCAATTC TTTCGGCACA GAGCTGTCCA AAGAGGACCG TGCCAAGCTC 
TTTCCACACT GTGGGCGGCT CTACCCTGAG GGCCTGGCGC AGCTGGCTCG GGCTGACGAC 
TATGAACAGG TCAAGAACGT GGCCGATTAC TACCCGGAGT ACAAGCTGCT CTTCGAGGGT 
GCAGGTAGCA ACCCTGGAGA CAAGACGCTG GAGGACCGAT TCTTTGAGCA CGAGGTAAAG 
CTGAACAAGT TGGCCTTCCT GAACCAGTTC CACTTTGGTG TCTTCTATGC CTTCGTGAAG 
CTCAAGGAGC AGGAGTGTCG CAACATCGTG TGGATCGCTG AATGTATCGC CCAGCGCCAC 
CGCGCCAAAA TCGACAACTA CATCCCTATC TTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V0D1 ( NM_004691.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004682.2 Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), mRNA.

Price & Availability↑

CloneID	OHu18928
Clone ID Related Accession (Same CDS sequence)	NM_004691.5 , NM_004691.4
Accession Version	NM_004691.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit d 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI552108.1, BC008861.2 and BM677562.1. This sequence is a reference standard in the RefSeqGene project. On Jan 27, 2006 this sequence version replaced NM_004691.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.64831.1, BC008861.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTTCT TCCCGGAGCT TTACTTTAAC GTGGACAATG GCTACTTGGA GGGACTGGTG 
CGCGGCCTGA AGGCCGGGGT GCTCAGCCAG GCCGACTACC TCAACCTGGT GCAGTGCGAG 
ACGCTAGAGG ACTTGAAACT GCATCTGCAG AGCACTGATT ATGGTAACTT CCTGGCCAAC 
GAGGCATCAC CTCTGACGGT GTCAGTCATC GATGACCGGC TCAAGGAGAA GATGGTGGTG 
GAGTTCCGCC ACATGAGGAA CCATGCCTAT GAGCCACTCG CCAGCTTCCT AGACTTCATT 
ACTTACAGTT ACATGATCGA CAACGTGATC CTGCTCATCA CAGGCACGCT GCACCAGCGC 
TCCATCGCTG AGCTCGTGCC CAAGTGCCAC CCACTAGGCA GCTTCGAGCA GATGGAGGCC 
GTGAACATTG CTCAGACACC TGCTGAGCTC TACAATGCCA TTCTGGTGGA CACGCCTCTT 
GCGGCTTTTT TCCAGGACTG CATTTCAGAG CAGGACCTTG ACGAGATGAA CATCGAGATC 
ATCCGCAACA CCCTCTACAA GGCCTACCTG GAGTCCTTCT ACAAGTTCTG CACCCTACTG 
GGCGGGACTA CGGCTGATGC CATGTGCCCC ATCCTGGAGT TTGAAGCAGA CCGCCGCGCC 
TTCATCATCA CCATCAATTC TTTCGGCACA GAGCTGTCCA AAGAGGACCG TGCCAAGCTC 
TTTCCACACT GTGGGCGGCT CTACCCTGAG GGCCTGGCGC AGCTGGCTCG GGCTGACGAC 
TATGAACAGG TCAAGAACGT GGCCGATTAC TACCCGGAGT ACAAGCTGCT CTTCGAGGGT 
GCAGGTAGCA ACCCTGGAGA CAAGACGCTG GAGGACCGAT TCTTTGAGCA CGAGGTAAAG 
CTGAACAAGT TGGCCTTCCT GAACCAGTTC CACTTTGGTG TCTTCTATGC CTTCGTGAAG 
CTCAAGGAGC AGGAGTGTCG CAACATCGTG TGGATCGCTG AATGTATCGC CCAGCGCCAC 
CGCGCCAAAA TCGACAACTA CATCCCTATC TTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004682.2
CDS	101..1156
Translation	MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLTVSVIDDRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF

Target ORF information:

RefSeq Version	NM_004691.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004691.4

ORF Insert Sequence:

ATGTCGTTCT TCCCGGAGCT TTACTTTAAC GTGGACAATG GCTACTTGGA GGGACTGGTG 
CGCGGCCTGA AGGCCGGGGT GCTCAGCCAG GCCGACTACC TCAACCTGGT GCAGTGCGAG 
ACGCTAGAGG ACTTGAAACT GCATCTGCAG AGCACTGATT ATGGTAACTT CCTGGCCAAC 
GAGGCATCAC CTCTGACGGT GTCAGTCATC GATGACCGGC TCAAGGAGAA GATGGTGGTG 
GAGTTCCGCC ACATGAGGAA CCATGCCTAT GAGCCACTCG CCAGCTTCCT AGACTTCATT 
ACTTACAGTT ACATGATCGA CAACGTGATC CTGCTCATCA CAGGCACGCT GCACCAGCGC 
TCCATCGCTG AGCTCGTGCC CAAGTGCCAC CCACTAGGCA GCTTCGAGCA GATGGAGGCC 
GTGAACATTG CTCAGACACC TGCTGAGCTC TACAATGCCA TTCTGGTGGA CACGCCTCTT 
GCGGCTTTTT TCCAGGACTG CATTTCAGAG CAGGACCTTG ACGAGATGAA CATCGAGATC 
ATCCGCAACA CCCTCTACAA GGCCTACCTG GAGTCCTTCT ACAAGTTCTG CACCCTACTG 
GGCGGGACTA CGGCTGATGC CATGTGCCCC ATCCTGGAGT TTGAAGCAGA CCGCCGCGCC 
TTCATCATCA CCATCAATTC TTTCGGCACA GAGCTGTCCA AAGAGGACCG TGCCAAGCTC 
TTTCCACACT GTGGGCGGCT CTACCCTGAG GGCCTGGCGC AGCTGGCTCG GGCTGACGAC 
TATGAACAGG TCAAGAACGT GGCCGATTAC TACCCGGAGT ACAAGCTGCT CTTCGAGGGT 
GCAGGTAGCA ACCCTGGAGA CAAGACGCTG GAGGACCGAT TCTTTGAGCA CGAGGTAAAG 
CTGAACAAGT TGGCCTTCCT GAACCAGTTC CACTTTGGTG TCTTCTATGC CTTCGTGAAG 
CTCAAGGAGC AGGAGTGTCG CAACATCGTG TGGATCGCTG AATGTATCGC CCAGCGCCAC 
CGCGCCAAAA TCGACAACTA CATCCCTATC TTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V0D1 ( XM_011523445.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011521747.1 Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu62487
Clone ID Related Accession (Same CDS sequence)	XM_011523445.1 , XM_011523446.1 , XM_011523444.1
Accession Version	XM_011523445.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit d 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGTGG AGTTCCGCCA CATGAGGAAC CATGCCTATG AGCCACTCGC CAGCTTCCTA 
GACTTCATTA CTTACAGTTA CATGATCGAC AACGTGATCC TGCTCATCAC AGGCACGCTG 
CACCAGCGCT CCATCGCTGA GCTCGTGCCC AAGTGCCACC CACTAGGCAG CTTCGAGCAG 
ATGGAGGCCG TGAACATTGC TCAGACACCT GCTGAGCTCT ACAATGCCAT TCTGGTGGAC 
ACGCCTCTTG CGGCTTTTTT CCAGGACTGC ATTTCAGAGC AGGACCTTGA CGAGATGAAC 
ATCGAGATCA TCCGCAACAC CCTCTACAAG GCCTACCTGG AGTCCTTCTA CAAGTTCTGC 
ACCCTACTGG GCGGGACTAC GGCTGATGCC ATGTGCCCCA TCCTGGAGTT TGAAGCAGAC 
CGCCGCGCCT TCATCATCAC CATCAATTCT TTCGGCACAG AGCTGTCCAA AGAGGACCGT 
GCCAAGCTCT TTCCACACTG TGGGCGGCTC TACCCTGAGG GCCTGGCGCA GCTGGCTCGG 
GCTGACGACT ATGAACAGGT CAAGAACGTG GCCGATTACT ACCCGGAGTA CAAGCTGCTC 
TTCGAGGGTG CAGGTAGCAA CCCTGGAGAC AAGACGCTGG AGGACCGATT CTTTGAGCAC 
GAGGTAAAGC TGAACAAGTT GGCCTTCCTG AACCAGTTCC ACTTTGGTGT CTTCTATGCC 
TTCGTGAAGC TCAAGGAGCA GGAGTGTCGC AACATCGTGT GGATCGCTGA ATGTATCGCC 
CAGCGCCACC GCGCCAAAAT CGACAACTAC ATCCCTATCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011521747.1
CDS	452..1276
Translation	MVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF

Target ORF information:

RefSeq Version	XM_011523445.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011523445.1

ORF Insert Sequence:

ATGGTGGTGG AGTTCCGCCA CATGAGGAAC CATGCCTATG AGCCACTCGC CAGCTTCCTA 
GACTTCATTA CTTACAGTTA CATGATCGAC AACGTGATCC TGCTCATCAC AGGCACGCTG 
CACCAGCGCT CCATCGCTGA GCTCGTGCCC AAGTGCCACC CACTAGGCAG CTTCGAGCAG 
ATGGAGGCCG TGAACATTGC TCAGACACCT GCTGAGCTCT ACAATGCCAT TCTGGTGGAC 
ACGCCTCTTG CGGCTTTTTT CCAGGACTGC ATTTCAGAGC AGGACCTTGA CGAGATGAAC 
ATCGAGATCA TCCGCAACAC CCTCTACAAG GCCTACCTGG AGTCCTTCTA CAAGTTCTGC 
ACCCTACTGG GCGGGACTAC GGCTGATGCC ATGTGCCCCA TCCTGGAGTT TGAAGCAGAC 
CGCCGCGCCT TCATCATCAC CATCAATTCT TTCGGCACAG AGCTGTCCAA AGAGGACCGT 
GCCAAGCTCT TTCCACACTG TGGGCGGCTC TACCCTGAGG GCCTGGCGCA GCTGGCTCGG 
GCTGACGACT ATGAACAGGT CAAGAACGTG GCCGATTACT ACCCGGAGTA CAAGCTGCTC 
TTCGAGGGTG CAGGTAGCAA CCCTGGAGAC AAGACGCTGG AGGACCGATT CTTTGAGCAC 
GAGGTAAAGC TGAACAAGTT GGCCTTCCTG AACCAGTTCC ACTTTGGTGT CTTCTATGCC 
TTCGTGAAGC TCAAGGAGCA GGAGTGTCGC AACATCGTGT GGATCGCTGA ATGTATCGCC 
CAGCGCCACC GCGCCAAAAT CGACAACTAC ATCCCTATCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V0D1 ( XM_011523446.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011521748.1 Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu62487
Clone ID Related Accession (Same CDS sequence)	XM_011523445.1 , XM_011523446.1 , XM_011523444.1
Accession Version	XM_011523446.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit d 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGTGG AGTTCCGCCA CATGAGGAAC CATGCCTATG AGCCACTCGC CAGCTTCCTA 
GACTTCATTA CTTACAGTTA CATGATCGAC AACGTGATCC TGCTCATCAC AGGCACGCTG 
CACCAGCGCT CCATCGCTGA GCTCGTGCCC AAGTGCCACC CACTAGGCAG CTTCGAGCAG 
ATGGAGGCCG TGAACATTGC TCAGACACCT GCTGAGCTCT ACAATGCCAT TCTGGTGGAC 
ACGCCTCTTG CGGCTTTTTT CCAGGACTGC ATTTCAGAGC AGGACCTTGA CGAGATGAAC 
ATCGAGATCA TCCGCAACAC CCTCTACAAG GCCTACCTGG AGTCCTTCTA CAAGTTCTGC 
ACCCTACTGG GCGGGACTAC GGCTGATGCC ATGTGCCCCA TCCTGGAGTT TGAAGCAGAC 
CGCCGCGCCT TCATCATCAC CATCAATTCT TTCGGCACAG AGCTGTCCAA AGAGGACCGT 
GCCAAGCTCT TTCCACACTG TGGGCGGCTC TACCCTGAGG GCCTGGCGCA GCTGGCTCGG 
GCTGACGACT ATGAACAGGT CAAGAACGTG GCCGATTACT ACCCGGAGTA CAAGCTGCTC 
TTCGAGGGTG CAGGTAGCAA CCCTGGAGAC AAGACGCTGG AGGACCGATT CTTTGAGCAC 
GAGGTAAAGC TGAACAAGTT GGCCTTCCTG AACCAGTTCC ACTTTGGTGT CTTCTATGCC 
TTCGTGAAGC TCAAGGAGCA GGAGTGTCGC AACATCGTGT GGATCGCTGA ATGTATCGCC 
CAGCGCCACC GCGCCAAAAT CGACAACTAC ATCCCTATCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011521748.1
CDS	224..1048
Translation	MVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF

Target ORF information:

RefSeq Version	XM_011523446.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011523446.1

ORF Insert Sequence:

ATGGTGGTGG AGTTCCGCCA CATGAGGAAC CATGCCTATG AGCCACTCGC CAGCTTCCTA 
GACTTCATTA CTTACAGTTA CATGATCGAC AACGTGATCC TGCTCATCAC AGGCACGCTG 
CACCAGCGCT CCATCGCTGA GCTCGTGCCC AAGTGCCACC CACTAGGCAG CTTCGAGCAG 
ATGGAGGCCG TGAACATTGC TCAGACACCT GCTGAGCTCT ACAATGCCAT TCTGGTGGAC 
ACGCCTCTTG CGGCTTTTTT CCAGGACTGC ATTTCAGAGC AGGACCTTGA CGAGATGAAC 
ATCGAGATCA TCCGCAACAC CCTCTACAAG GCCTACCTGG AGTCCTTCTA CAAGTTCTGC 
ACCCTACTGG GCGGGACTAC GGCTGATGCC ATGTGCCCCA TCCTGGAGTT TGAAGCAGAC 
CGCCGCGCCT TCATCATCAC CATCAATTCT TTCGGCACAG AGCTGTCCAA AGAGGACCGT 
GCCAAGCTCT TTCCACACTG TGGGCGGCTC TACCCTGAGG GCCTGGCGCA GCTGGCTCGG 
GCTGACGACT ATGAACAGGT CAAGAACGTG GCCGATTACT ACCCGGAGTA CAAGCTGCTC 
TTCGAGGGTG CAGGTAGCAA CCCTGGAGAC AAGACGCTGG AGGACCGATT CTTTGAGCAC 
GAGGTAAAGC TGAACAAGTT GGCCTTCCTG AACCAGTTCC ACTTTGGTGT CTTCTATGCC 
TTCGTGAAGC TCAAGGAGCA GGAGTGTCGC AACATCGTGT GGATCGCTGA ATGTATCGCC 
CAGCGCCACC GCGCCAAAAT CGACAACTAC ATCCCTATCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V0D1 ( XM_011523444.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011521746.1 Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu62487
Clone ID Related Accession (Same CDS sequence)	XM_011523445.1 , XM_011523446.1 , XM_011523444.1
Accession Version	XM_011523444.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit d 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGTGG AGTTCCGCCA CATGAGGAAC CATGCCTATG AGCCACTCGC CAGCTTCCTA 
GACTTCATTA CTTACAGTTA CATGATCGAC AACGTGATCC TGCTCATCAC AGGCACGCTG 
CACCAGCGCT CCATCGCTGA GCTCGTGCCC AAGTGCCACC CACTAGGCAG CTTCGAGCAG 
ATGGAGGCCG TGAACATTGC TCAGACACCT GCTGAGCTCT ACAATGCCAT TCTGGTGGAC 
ACGCCTCTTG CGGCTTTTTT CCAGGACTGC ATTTCAGAGC AGGACCTTGA CGAGATGAAC 
ATCGAGATCA TCCGCAACAC CCTCTACAAG GCCTACCTGG AGTCCTTCTA CAAGTTCTGC 
ACCCTACTGG GCGGGACTAC GGCTGATGCC ATGTGCCCCA TCCTGGAGTT TGAAGCAGAC 
CGCCGCGCCT TCATCATCAC CATCAATTCT TTCGGCACAG AGCTGTCCAA AGAGGACCGT 
GCCAAGCTCT TTCCACACTG TGGGCGGCTC TACCCTGAGG GCCTGGCGCA GCTGGCTCGG 
GCTGACGACT ATGAACAGGT CAAGAACGTG GCCGATTACT ACCCGGAGTA CAAGCTGCTC 
TTCGAGGGTG CAGGTAGCAA CCCTGGAGAC AAGACGCTGG AGGACCGATT CTTTGAGCAC 
GAGGTAAAGC TGAACAAGTT GGCCTTCCTG AACCAGTTCC ACTTTGGTGT CTTCTATGCC 
TTCGTGAAGC TCAAGGAGCA GGAGTGTCGC AACATCGTGT GGATCGCTGA ATGTATCGCC 
CAGCGCCACC GCGCCAAAAT CGACAACTAC ATCCCTATCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011521746.1
CDS	319..1143
Translation	MVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF

Target ORF information:

RefSeq Version	XM_011523444.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V0 subunit d1 (ATP6V0D1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011523444.1

ORF Insert Sequence:

ATGGTGGTGG AGTTCCGCCA CATGAGGAAC CATGCCTATG AGCCACTCGC CAGCTTCCTA 
GACTTCATTA CTTACAGTTA CATGATCGAC AACGTGATCC TGCTCATCAC AGGCACGCTG 
CACCAGCGCT CCATCGCTGA GCTCGTGCCC AAGTGCCACC CACTAGGCAG CTTCGAGCAG 
ATGGAGGCCG TGAACATTGC TCAGACACCT GCTGAGCTCT ACAATGCCAT TCTGGTGGAC 
ACGCCTCTTG CGGCTTTTTT CCAGGACTGC ATTTCAGAGC AGGACCTTGA CGAGATGAAC 
ATCGAGATCA TCCGCAACAC CCTCTACAAG GCCTACCTGG AGTCCTTCTA CAAGTTCTGC 
ACCCTACTGG GCGGGACTAC GGCTGATGCC ATGTGCCCCA TCCTGGAGTT TGAAGCAGAC 
CGCCGCGCCT TCATCATCAC CATCAATTCT TTCGGCACAG AGCTGTCCAA AGAGGACCGT 
GCCAAGCTCT TTCCACACTG TGGGCGGCTC TACCCTGAGG GCCTGGCGCA GCTGGCTCGG 
GCTGACGACT ATGAACAGGT CAAGAACGTG GCCGATTACT ACCCGGAGTA CAAGCTGCTC 
TTCGAGGGTG CAGGTAGCAA CCCTGGAGAC AAGACGCTGG AGGACCGATT CTTTGAGCAC 
GAGGTAAAGC TGAACAAGTT GGCCTTCCTG AACCAGTTCC ACTTTGGTGT CTTCTATGCC 
TTCGTGAAGC TCAAGGAGCA GGAGTGTCGC AACATCGTGT GGATCGCTGA ATGTATCGCC 
CAGCGCCACC GCGCCAAAAT CGACAACTAC ATCCCTATCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels.
eLife6(2017 03)
Miles AL,Burr SP,Grice GL,Nathan JA

Expression, purification and characterization of human vacuolar-type H(+)-ATPase subunit d1 and d2 in Escherichia coli.
Protein expression and purification9825-31(2014 Jun)
Lim H,Cheong HK,Rho JR,Hyun JK,Kim YJ

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.
Free radical biology & medicine53(9)1760-9(2012 Nov)
H?hn A,Sittig A,Jung T,Grimm S,Grune T

A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo.
Cell research22(2)333-45(2012 Feb)
Chen Y,Wu B,Xu L,Li H,Xia J,Yin W,Li Z,Shi D,Li S,Lin S,Shu X,Pei D

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ATP6V0D1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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