TBX19 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TBX19
Entrez Gene ID	9095
Full Name	T-box 19
Synonyms	TBS19,TPIT,dJ747L4.1
General protein information	Preferred Names T-box 19 Names T-box transcription factor TBX19 T-box factor, pituitary T-box protein 19 TBS 19
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q24.2
Summary	This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008].
Disorder MIM:	604614
Disorder Html:	Adrenocorticotropic hormone deficiency, 201400 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005149.2	NP_005140.1	T-box transcription factor TBX19
NM_005149.3	NP_005140.1	T-box transcription factor TBX19

Pathways from BioSystems

Homologies

Homo sapiens (human)	TBX19	NP_005140.1
Pan troglodytes (chimpanzee)	TBX19	XP_001174854.1
Canis lupus familiaris (dog)	TBX19	NP_001005758.1
Bos taurus (cattle)	TBX19	NP_001069131.1
Mus musculus (house mouse)	Tbx19	NP_114394.1
Gallus gallus (chicken)	TBX19	NP_990281.1
	TBX19	XP_001092175.1
Danio rerio (zebrafish)	LOC100538180	XP_003198807.1

Gene Ontology
Bibliography

Related articles in PubMed

TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis.
Ando J, Saito M, Imai JI, Ito E, Yanagisawa Y, Honma R, Saito K, Tachibana K, Momma T, Ohki S, Ohtake T, Watanabe S, Waguri S, Kono K, Takenoshita S
Fukushima journal of medical science63(3)141-151(2017 Dec)

Identification of TPIT and other novel autoantigens in lymphocytic hypophysitis: immunoscreening of a pituitary cDNA library and development of immunoprecipitation assays.
Smith CJ, Bensing S, Burns C, Robinson PJ, Kasperlik-Zaluska AA, Scott RJ, K?mpe O, Crock PA
European journal of endocrinology166(3)391-8(2012 Mar)

Phenotypic homogeneity and genotypic variability in a large series of congenital isolated ACTH-deficiency patients with TPIT gene mutations.
Couture C, Saveanu A, Barlier A, Carel JC, Fassnacht M, Fl?ck CE, Houang M, Maes M, Phan-Hug F, Enjalbert A, Drouin J, Brue T, Vallette S
The Journal of clinical endocrinology and metabolism97(3)E486-95(2012 Mar)

The Ets factor Etv1 interacts with Tpit protein for pituitary pro-opiomelanocortin (POMC) gene transcription.
Budry L, Couture C, Balsalobre A, Drouin J
The Journal of biological chemistry286(28)25387-96(2011 Jul)

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
Ehret GB, O'Connor AA, Weder A, Cooper RS, Chakravarti A
European journal of human genetics : EJHG17(12)1650-7(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TPIT is identified as a target autoantigen in 10.5% of patients with lymphocytic hypophysitis.
Title: Identification of TPIT and other novel autoantigens in lymphocytic hypophysitis: immunoscreening of a pituitary cDNA library and development of immunoprecipitation assays.

Identification of nine new TPIT mutations in a large series of congenital isolated ACTH-deficiency patients.
Title: Phenotypic homogeneity and genotypic variability in a large series of congenital isolated ACTH-deficiency patients with TPIT gene mutations.

The coordinate expression of Etv1 with POMC cell differentiation and its interaction with the highly cell-restricted Tpit factor indicate that Etv1 participates in a combinatorial code for pituitary cell-specific gene expression.
Title: The Ets factor Etv1 interacts with Tpit protein for pituitary pro-opiomelanocortin (POMC) gene transcription.

Observational study of gene-disease association. (HuGE Navigator)
Title: Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.

The following TBX19 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TBX19 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18433	NM_005149.3 Latest version!	Homo sapiens T-box transcription factor 19 (TBX19), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu18433	NM_005149.2	Homo sapiens T-box 19 (TBX19), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TBX19 ( NM_005149.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005140.1 Homo sapiens T-box 19 (TBX19), mRNA.

Price & Availability↑

CloneID	OHu18433
Clone ID Related Accession (Same CDS sequence)	NM_005149.2 , NM_005149.3
Accession Version	NM_005149.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	T-box transcription factor TBX19
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ010277.1 and AK091404.1. This sequence is a reference standard in the RefSeqGene project. On Mar 22, 2008 this sequence version replaced NM_005149.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ010277.1, BC093664.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGA GTGAGCTGGG CACTCGGAAG CCCAGCGATG GCACTGTTTC TCATCTGCTC 
AATGTGGTGG AGAGTGAGCT TCAGGCAGGG AGGGAAAAAG GCGACCCTAC GGAGAAGCAA 
CTTCAGATCA TCCTGGAGGA TGCACCTCTC TGGCAGAGAT TCAAGGAAGT CACTAATGAG 
ATGATTGTGA CCAAGAATGG CAGACGGATG TTTCCAGTCC TAAAGATTAG TGTCACAGGG 
TTGGACCCCA ATGCCATGTA CTCCCTCCTG CTGGACTTTG TCCCTACGGA CAGTCACCGC 
TGGAAGTACG TCAACGGGGA ATGGGTGCCC GCTGGCAAGC CAGAGGTCTC CAGCCACAGC 
TGCGTCTACA TTCACCCGGA CTCCCCCAAC TTTGGGGCCC ACTGGATGAA AGCTCCCATC 
TCCTTCAGCA AAGTGAAGCT GACCAACAAG CTCAATGGAG GCGGGCAGAT AATGTTGAAT 
TCTCTGCATA AATATGAACC CCAGGTTCAC ATAGTGCGTG TTGGAAGTGC CCATCGAATG 
GTAACAAACT GCTCCTTCCC TGAAACCCAG TTCATAGCCG TGACTGCCTA TCAGAATGAG 
GAGATAACGG CTCTCAAAAT CAAGTACAAT CCTTTTGCCA AAGCCTTCTT GGATGCCAAG 
GAAAGAAATC ACCTAAGAGA CGTACCGGAG GCTATCTCTG AGAGCCAGCA TGTGACCTAT 
TCTCACTTGG GAGGCTGGAT CTTTTCCAAT CCAGATGGAG TGTGCACAGC AGGAAACTCC 
AATTACCAGT ATGCCGCTCC TCTGCCTCTG CCTGCTCCCC ACACCCACCA TGGCTGTGAG 
CACTATTCGG GTCTCCGAGG ACACCGGCAG GCTCCCTACC CTTCTGCGTA CATGCACAGA 
AACCATTCTC CCTCAGTGAA TTTGATAGAA AGCTCAAGCA ATAATCTGCA AGTTTTCTCG 
GGACCTGACA GCTGGACTTC CTTATCCTCC ACACCCCATG CCAGCATCCT GTCTGTACCC 
CACACCAACG GACCAATCAA TCCAGGGCCC AGCCCCTACC CGTGCCTGTG GACCATCAGC 
AATGGTGCCG GAGGCCCCAG TGGGCCAGGC CCGGAGGTGC ACGCCAGCAC CCCAGGAGCA 
TTTCTCCTCG GAAACCCAGC TGTGACTTCA CCCCCTTCTG TGCTCTCCAC CCAAGCACCC 
ACTTCGGCTG GTGTGGAGGT TCTGGGGGAG CCCTCGCTAA CCAGCATTGC TGTGTCCACC 
TGGACAGCAG TGGCCTCGCA TCCCTTCGCG GGCTGGGGTG GCCCAGGAGC GGGTGGGCAC 
CATTCTCCTT CCTCACTGGA TGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005140.1
CDS	52..1398
Translation	MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVSTWTAVASHPFAGWGGPGAGGHHSPSSLDG

Target ORF information:

RefSeq Version	NM_005149.2
Organism	Homo sapiens(human)
Definition	Homo sapiens T-box 19 (TBX19), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005149.2

ORF Insert Sequence:

ATGGCCATGA GTGAGCTGGG CACTCGGAAG CCCAGCGATG GCACTGTTTC TCATCTGCTC 
AATGTGGTGG AGAGTGAGCT TCAGGCAGGG AGGGAAAAAG GCGACCCTAC GGAGAAGCAA 
CTTCAGATCA TCCTGGAGGA TGCACCTCTC TGGCAGAGAT TCAAGGAAGT CACTAATGAG 
ATGATTGTGA CCAAGAATGG CAGACGGATG TTTCCAGTCC TAAAGATTAG TGTCACAGGG 
TTGGACCCCA ATGCCATGTA CTCCCTCCTG CTGGACTTTG TCCCTACGGA CAGTCACCGC 
TGGAAGTACG TCAACGGGGA ATGGGTGCCC GCTGGCAAGC CAGAGGTCTC CAGCCACAGC 
TGCGTCTACA TTCACCCGGA CTCCCCCAAC TTTGGGGCCC ACTGGATGAA AGCTCCCATC 
TCCTTCAGCA AAGTGAAGCT GACCAACAAG CTCAATGGAG GCGGGCAGAT AATGTTGAAT 
TCTCTGCATA AATATGAACC CCAGGTTCAC ATAGTGCGTG TTGGAAGTGC CCATCGAATG 
GTAACAAACT GCTCCTTCCC TGAAACCCAG TTCATAGCCG TGACTGCCTA TCAGAATGAG 
GAGATAACGG CTCTCAAAAT CAAGTACAAT CCTTTTGCCA AAGCCTTCTT GGATGCCAAG 
GAAAGAAATC ACCTAAGAGA CGTACCGGAG GCTATCTCTG AGAGCCAGCA TGTGACCTAT 
TCTCACTTGG GAGGCTGGAT CTTTTCCAAT CCAGATGGAG TGTGCACAGC AGGAAACTCC 
AATTACCAGT ATGCCGCTCC TCTGCCTCTG CCTGCTCCCC ACACCCACCA TGGCTGTGAG 
CACTATTCGG GTCTCCGAGG ACACCGGCAG GCTCCCTACC CTTCTGCGTA CATGCACAGA 
AACCATTCTC CCTCAGTGAA TTTGATAGAA AGCTCAAGCA ATAATCTGCA AGTTTTCTCG 
GGACCTGACA GCTGGACTTC CTTATCCTCC ACACCCCATG CCAGCATCCT GTCTGTACCC 
CACACCAACG GACCAATCAA TCCAGGGCCC AGCCCCTACC CGTGCCTGTG GACCATCAGC 
AATGGTGCCG GAGGCCCCAG TGGGCCAGGC CCGGAGGTGC ACGCCAGCAC CCCAGGAGCA 
TTTCTCCTCG GAAACCCAGC TGTGACTTCA CCCCCTTCTG TGCTCTCCAC CCAAGCACCC 
ACTTCGGCTG GTGTGGAGGT TCTGGGGGAG CCCTCGCTAA CCAGCATTGC TGTGTCCACC 
TGGACAGCAG TGGCCTCGCA TCCCTTCGCG GGCTGGGGTG GCCCAGGAGC GGGTGGGCAC 
CATTCTCCTT CCTCACTGGA TGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TBX19 ( NM_005149.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005140.1 Homo sapiens T-box transcription factor 19 (TBX19), mRNA.

Price & Availability↑

CloneID	OHu18433
Clone ID Related Accession (Same CDS sequence)	NM_005149.2 , NM_005149.3
Accession Version	NM_005149.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	T-box transcription factor TBX19
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL009051.1, AJ010277.1 and AK091404.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_005149.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ010277.1, BC093664.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367821.8/ ENSP00000356795.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCATGA GTGAGCTGGG CACTCGGAAG CCCAGCGATG GCACTGTTTC TCATCTGCTC 
AATGTGGTGG AGAGTGAGCT TCAGGCAGGG AGGGAAAAAG GCGACCCTAC GGAGAAGCAA 
CTTCAGATCA TCCTGGAGGA TGCACCTCTC TGGCAGAGAT TCAAGGAAGT CACTAATGAG 
ATGATTGTGA CCAAGAATGG CAGACGGATG TTTCCAGTCC TAAAGATTAG TGTCACAGGG 
TTGGACCCCA ATGCCATGTA CTCCCTCCTG CTGGACTTTG TCCCTACGGA CAGTCACCGC 
TGGAAGTACG TCAACGGGGA ATGGGTGCCC GCTGGCAAGC CAGAGGTCTC CAGCCACAGC 
TGCGTCTACA TTCACCCGGA CTCCCCCAAC TTTGGGGCCC ACTGGATGAA AGCTCCCATC 
TCCTTCAGCA AAGTGAAGCT GACCAACAAG CTCAATGGAG GCGGGCAGAT AATGTTGAAT 
TCTCTGCATA AATATGAACC CCAGGTTCAC ATAGTGCGTG TTGGAAGTGC CCATCGAATG 
GTAACAAACT GCTCCTTCCC TGAAACCCAG TTCATAGCCG TGACTGCCTA TCAGAATGAG 
GAGATAACGG CTCTCAAAAT CAAGTACAAT CCTTTTGCCA AAGCCTTCTT GGATGCCAAG 
GAAAGAAATC ACCTAAGAGA CGTACCGGAG GCTATCTCTG AGAGCCAGCA TGTGACCTAT 
TCTCACTTGG GAGGCTGGAT CTTTTCCAAT CCAGATGGAG TGTGCACAGC AGGAAACTCC 
AATTACCAGT ATGCCGCTCC TCTGCCTCTG CCTGCTCCCC ACACCCACCA TGGCTGTGAG 
CACTATTCGG GTCTCCGAGG ACACCGGCAG GCTCCCTACC CTTCTGCGTA CATGCACAGA 
AACCATTCTC CCTCAGTGAA TTTGATAGAA AGCTCAAGCA ATAATCTGCA AGTTTTCTCG 
GGACCTGACA GCTGGACTTC CTTATCCTCC ACACCCCATG CCAGCATCCT GTCTGTACCC 
CACACCAACG GACCAATCAA TCCAGGGCCC AGCCCCTACC CGTGCCTGTG GACCATCAGC 
AATGGTGCCG GAGGCCCCAG TGGGCCAGGC CCGGAGGTGC ACGCCAGCAC CCCAGGAGCA 
TTTCTCCTCG GAAACCCAGC TGTGACTTCA CCCCCTTCTG TGCTCTCCAC CCAAGCACCC 
ACTTCGGCTG GTGTGGAGGT TCTGGGGGAG CCCTCGCTAA CCAGCATTGC TGTGTCCACC 
TGGACAGCAG TGGCCTCGCA TCCCTTCGCG GGCTGGGGTG GCCCAGGAGC GGGTGGGCAC 
CATTCTCCTT CCTCACTGGA TGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005140.1
CDS	215..1561
Translation	MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVSTWTAVASHPFAGWGGPGAGGHHSPSSLDG

Target ORF information:

RefSeq Version	NM_005149.3
Organism	Homo sapiens(human)
Definition	Homo sapiens T-box transcription factor 19 (TBX19), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005149.3

ORF Insert Sequence:

ATGGCCATGA GTGAGCTGGG CACTCGGAAG CCCAGCGATG GCACTGTTTC TCATCTGCTC 
AATGTGGTGG AGAGTGAGCT TCAGGCAGGG AGGGAAAAAG GCGACCCTAC GGAGAAGCAA 
CTTCAGATCA TCCTGGAGGA TGCACCTCTC TGGCAGAGAT TCAAGGAAGT CACTAATGAG 
ATGATTGTGA CCAAGAATGG CAGACGGATG TTTCCAGTCC TAAAGATTAG TGTCACAGGG 
TTGGACCCCA ATGCCATGTA CTCCCTCCTG CTGGACTTTG TCCCTACGGA CAGTCACCGC 
TGGAAGTACG TCAACGGGGA ATGGGTGCCC GCTGGCAAGC CAGAGGTCTC CAGCCACAGC 
TGCGTCTACA TTCACCCGGA CTCCCCCAAC TTTGGGGCCC ACTGGATGAA AGCTCCCATC 
TCCTTCAGCA AAGTGAAGCT GACCAACAAG CTCAATGGAG GCGGGCAGAT AATGTTGAAT 
TCTCTGCATA AATATGAACC CCAGGTTCAC ATAGTGCGTG TTGGAAGTGC CCATCGAATG 
GTAACAAACT GCTCCTTCCC TGAAACCCAG TTCATAGCCG TGACTGCCTA TCAGAATGAG 
GAGATAACGG CTCTCAAAAT CAAGTACAAT CCTTTTGCCA AAGCCTTCTT GGATGCCAAG 
GAAAGAAATC ACCTAAGAGA CGTACCGGAG GCTATCTCTG AGAGCCAGCA TGTGACCTAT 
TCTCACTTGG GAGGCTGGAT CTTTTCCAAT CCAGATGGAG TGTGCACAGC AGGAAACTCC 
AATTACCAGT ATGCCGCTCC TCTGCCTCTG CCTGCTCCCC ACACCCACCA TGGCTGTGAG 
CACTATTCGG GTCTCCGAGG ACACCGGCAG GCTCCCTACC CTTCTGCGTA CATGCACAGA 
AACCATTCTC CCTCAGTGAA TTTGATAGAA AGCTCAAGCA ATAATCTGCA AGTTTTCTCG 
GGACCTGACA GCTGGACTTC CTTATCCTCC ACACCCCATG CCAGCATCCT GTCTGTACCC 
CACACCAACG GACCAATCAA TCCAGGGCCC AGCCCCTACC CGTGCCTGTG GACCATCAGC 
AATGGTGCCG GAGGCCCCAG TGGGCCAGGC CCGGAGGTGC ACGCCAGCAC CCCAGGAGCA 
TTTCTCCTCG GAAACCCAGC TGTGACTTCA CCCCCTTCTG TGCTCTCCAC CCAAGCACCC 
ACTTCGGCTG GTGTGGAGGT TCTGGGGGAG CCCTCGCTAA CCAGCATTGC TGTGTCCACC 
TGGACAGCAG TGGCCTCGCA TCCCTTCGCG GGCTGGGGTG GCCCAGGAGC GGGTGGGCAC 
CATTCTCCTT CCTCACTGGA TGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis.
Fukushima journal of medical science63(3)141-151(2017 Dec)
Ando J,Saito M,Imai JI,Ito E,Yanagisawa Y,Honma R,Saito K,Tachibana K,Momma T,Ohki S,Ohtake T,Watanabe S,Waguri S,Kono K,Takenoshita S

Identification of TPIT and other novel autoantigens in lymphocytic hypophysitis: immunoscreening of a pituitary cDNA library and development of immunoprecipitation assays.
European journal of endocrinology166(3)391-8(2012 Mar)
Smith CJ,Bensing S,Burns C,Robinson PJ,Kasperlik-Zaluska AA,Scott RJ,K?mpe O,Crock PA

Phenotypic homogeneity and genotypic variability in a large series of congenital isolated ACTH-deficiency patients with TPIT gene mutations.
The Journal of clinical endocrinology and metabolism97(3)E486-95(2012 Mar)
Couture C,Saveanu A,Barlier A,Carel JC,Fassnacht M,Fl?ck CE,Houang M,Maes M,Phan-Hug F,Enjalbert A,Drouin J,Brue T,Vallette S

The Ets factor Etv1 interacts with Tpit protein for pituitary pro-opiomelanocortin (POMC) gene transcription.
The Journal of biological chemistry286(28)25387-96(2011 Jul)
Budry L,Couture C,Balsalobre A,Drouin J

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
European journal of human genetics : EJHG17(12)1650-7(2009 Dec)
Ehret GB,O'Connor AA,Weder A,Cooper RS,Chakravarti A

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TBX19 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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